-
1
-
-
0242585476
-
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis
-
H. Aguilaniu, L. Gustafsson, M. Rigoulet, and T. Nystrom Asymmetric inheritance of oxidatively damaged proteins during cytokinesis Science 299 2003 1751 1753
-
(2003)
Science
, vol.299
, pp. 1751-1753
-
-
Aguilaniu, H.1
Gustafsson, L.2
Rigoulet, M.3
Nystrom, T.4
-
2
-
-
0030841350
-
Protein oxidation in aging, disease, and oxidative stress
-
B.S. Berlett, and E.R. Stadtman Protein oxidation in aging, disease, and oxidative stress J. Biol. Chem. 272 1997 20313 20316
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20313-20316
-
-
Berlett, B.S.1
Stadtman, E.R.2
-
3
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
G. Blander, and L. Guarente The Sir2 family of protein deacetylases Annu. Rev. Biochem. 73 2004 417 435
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
4
-
-
0141866708
-
Superoxide dismutase 1 knock-down induces senescence in human fibroblasts
-
G. Blander, R.M. de Oliveira, C.M. Conboy, M. Haigis, and L. Guarente Superoxide dismutase 1 knock-down induces senescence in human fibroblasts J. Biol. Chem. 278 2003 38966 38969
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38966-38969
-
-
Blander, G.1
De Oliveira, R.M.2
Conboy, C.M.3
Haigis, M.4
Guarente, L.5
-
5
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
M. Bluher, B.B. Kahn, and C.R. Kahn Extended longevity in mice lacking the insulin receptor in adipose tissue Science 299 2003 572 574
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Bluher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
6
-
-
0141531999
-
Metabolic network control of oxidative phosphorylation: Multiple roles of inorganic phosphate
-
S. Bose, S. French, F.J. Evans, F. Joubert, and R.S. Balaban Metabolic network control of oxidative phosphorylation: multiple roles of inorganic phosphate J. Biol. Chem. 278 2003 39155 39165
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39155-39165
-
-
Bose, S.1
French, S.2
Evans, F.J.3
Joubert, F.4
Balaban, R.S.5
-
7
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
A. Boveris, and B. Chance The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen Biochem. J. 134 1973 707 716
-
(1973)
Biochem. J.
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
8
-
-
0015363173
-
The cellular production of hydrogen peroxide
-
A. Boveris, N. Oshino, and B. Chance The cellular production of hydrogen peroxide Biochem. J. 128 1972 617 630
-
(1972)
Biochem. J.
, vol.128
, pp. 617-630
-
-
Boveris, A.1
Oshino, N.2
Chance, B.3
-
9
-
-
0036757226
-
No reduction of energy metabolism in Clk mutants
-
B.P. Braeckman, K. Houthoofd, K. Brys, I. Lenaerts, A. De Vreese, S. Van Eygen, H. Raes, and J.R. Vanfleteren No reduction of energy metabolism in Clk mutants Mech. Ageing Dev. 123 2002 1447 1456
-
(2002)
Mech. Ageing Dev.
, vol.123
, pp. 1447-1456
-
-
Braeckman, B.P.1
Houthoofd, K.2
Brys, K.3
Lenaerts, I.4
De Vreese, A.5
Van Eygen, S.6
Raes, H.7
Vanfleteren, J.R.8
-
10
-
-
0033785071
-
Uncoupling to survive? the role of mitochondrial inefficiency in ageing
-
M.D. Brand Uncoupling to survive? The role of mitochondrial inefficiency in ageing Exp. Gerontol. 35 2000 811 820
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 811-820
-
-
Brand, M.D.1
-
11
-
-
4043147798
-
Mitochondrial superoxide: Production, biological effects, and activation of uncoupling proteins
-
M.D. Brand, C. Affourtit, T.C. Esteves, K. Green, A.J. Lambert, S. Miwa, J.L. Pakay, and N. Parker Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins Free Radic. Biol. Med. 37 2004 755 767
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 755-767
-
-
Brand, M.D.1
Affourtit, C.2
Esteves, T.C.3
Green, K.4
Lambert, A.J.5
Miwa, S.6
Pakay, J.L.7
Parker, N.8
-
12
-
-
0343340109
-
Clk-1, mitochondria, and physiological rates
-
R. Branicky, C. Benard, and S. Hekimi clk-1, mitochondria, and physiological rates Bioessays 22 2000 48 56
-
(2000)
Bioessays
, vol.22
, pp. 48-56
-
-
Branicky, R.1
Benard, C.2
Hekimi, S.3
-
13
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
A. Brunet, L.B. Sweeney, J.F. Sturgill, K.F. Chua, P.L. Greer, Y. Lin, H. Tran, S.E. Ross, R. Mostoslavsky, and H.Y. Cohen Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2004 2011 2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
14
-
-
0016719078
-
The reaction between the superoxide anion radical and cytochrome c
-
J. Butler, G.G. Jayson, and A.J. Swallow The reaction between the superoxide anion radical and cytochrome c Biochim. Biophys. Acta 408 1975 215 222
-
(1975)
Biochim. Biophys. Acta
, vol.408
, pp. 215-222
-
-
Butler, J.1
Jayson, G.G.2
Swallow, A.J.3
-
15
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
E. Cadenas, and K.J. Davies Mitochondrial free radical generation, oxidative stress, and aging Free Radic. Biol. Med. 29 2000 222 230
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
16
-
-
0036138596
-
Mitochondrial ROS metabolism: Modulation by uncoupling proteins
-
L. Casteilla, M. Rigoulet, and L. Penicaud Mitochondrial ROS metabolism: modulation by uncoupling proteins IUBMB Life 52 2001 181 188
-
(2001)
IUBMB Life
, vol.52
, pp. 181-188
-
-
Casteilla, L.1
Rigoulet, M.2
Penicaud, L.3
-
17
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
B. Chance, H. Sies, and A. Boveris Hydroperoxide metabolism in mammalian organs Physiol. Rev. 59 1979 527 605
-
(1979)
Physiol. Rev.
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
18
-
-
4744373181
-
Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria
-
10.1074/jbc.M407707200.
-
T.S. Chang, C.S. Cho, S. Park, S. Yu, S.W. Kang, and S.G. Rhee Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria J. Biol. Chem. 279 2004 41975 41984 10.1074/jbc.M407707200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41975-41984
-
-
Chang, T.S.1
Cho, C.S.2
Park, S.3
Yu, S.4
Kang, S.W.5
Rhee, S.G.6
-
19
-
-
0141815741
-
Production of reactive oxygen species by mitochondria: Central role of complex III
-
Q. Chen, E.J. Vazquez, S. Moghaddas, C.L. Hoppel, and E.J. Lesnefsky Production of reactive oxygen species by mitochondria: central role of complex III J. Biol. Chem. 278 2003 36027 36031
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36027-36031
-
-
Chen, Q.1
Vazquez, E.J.2
Moghaddas, S.3
Hoppel, C.L.4
Lesnefsky, E.J.5
-
20
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
D.J. Clancy, D. Gems, L.G. Harshman, S. Oldham, H. Stocker, E. Hafen, S.J. Leevers, and L. Partridge Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein Science 292 2001 104 106
-
(2001)
Science
, vol.292
, pp. 104-106
-
-
Clancy, D.J.1
Gems, D.2
Harshman, L.G.3
Oldham, S.4
Stocker, H.5
Hafen, E.6
Leevers, S.J.7
Partridge, L.8
-
21
-
-
2942748080
-
The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila
-
S. Cvejic, Z. Zhu, S.J. Felice, Y. Berman, and X.Y. Huang The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila Nat. Cell Biol. 6 2004 540 546
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 540-546
-
-
Cvejic, S.1
Zhu, Z.2
Felice, S.J.3
Berman, Y.4
Huang, X.Y.5
-
22
-
-
0037380667
-
Hypoxia-induced endocytosis of Na, K-ATPase in aveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-zeta
-
L.A. Dada, N.S. Chandel, K.M. Ridge, C. Pedemonte, A.M. Bertorello, and J.I. Sznajder Hypoxia-induced endocytosis of Na, K-ATPase in aveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-zeta J. Clin. Invest. 111 2003 1057 1064
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1057-1064
-
-
Dada, L.A.1
Chandel, N.S.2
Ridge, K.M.3
Pedemonte, C.4
Bertorello, A.M.5
Sznajder, J.I.6
-
23
-
-
0037221445
-
Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases
-
J.M. Denu Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases Trends Biochem. Sci. 28 2003 41 48
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 41-48
-
-
Denu, J.M.1
-
24
-
-
0037147103
-
Rates of behavior and aging specified by mitochondrial function during development
-
A. Dillin, A.L. Hsu, N. Arantes-Oliveira, J. Lehrer-Graiwer, H. Hsin, A.G. Fraser, R.S. Kamath, J. Ahringer, and C. Kenyon Rates of behavior and aging specified by mitochondrial function during development Science 298 2002 2398 2401
-
(2002)
Science
, vol.298
, pp. 2398-2401
-
-
Dillin, A.1
Hsu, A.L.2
Arantes-Oliveira, N.3
Lehrer-Graiwer, J.4
Hsin, H.5
Fraser, A.G.6
Kamath, R.S.7
Ahringer, J.8
Kenyon, C.9
-
25
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
K.S. Echtay, D. Roussel, J. St-Pierre, M.B. Jekabsons, S. Cadenas, J.A. Stuart, J.A. Harper, S.J. Roebuck, A. Morrison, and S. Pickering Superoxide activates mitochondrial uncoupling proteins Nature 415 2002 96 99
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
Jekabsons, M.B.4
Cadenas, S.5
Stuart, J.A.6
Harper, J.A.7
Roebuck, S.J.8
Morrison, A.9
Pickering, S.10
-
26
-
-
0031030678
-
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1
-
J.J. Ewbank, T.M. Barnes, B. Lakowski, M. Lussier, H. Bussey, and S. Hekimi Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1 Science 275 1997 980 983
-
(1997)
Science
, vol.275
, pp. 980-983
-
-
Ewbank, J.J.1
Barnes, T.M.2
Lakowski, B.3
Lussier, M.4
Bussey, H.5
Hekimi, S.6
-
27
-
-
0033118981
-
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans
-
S. Felkai, J.J. Ewbank, J. Lemieux, J.C. Labbe, G.G. Brown, and S. Hekimi CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans EMBO J. 18 1999 1783 1792
-
(1999)
EMBO J.
, vol.18
, pp. 1783-1792
-
-
Felkai, S.1
Ewbank, J.J.2
Lemieux, J.3
Labbe, J.C.4
Brown, G.G.5
Hekimi, S.6
-
28
-
-
0035515923
-
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
-
J. Feng, F. Bussiere, and S. Hekimi Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans Dev. Cell 1 2001 633 644
-
(2001)
Dev. Cell
, vol.1
, pp. 633-644
-
-
Feng, J.1
Bussiere, F.2
Hekimi, S.3
-
29
-
-
0037376674
-
Oxidant signals and oxidative stress
-
T. Finkel Oxidant signals and oxidative stress Curr. Opin. Cell Biol. 15 2003 247 254
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 247-254
-
-
Finkel, T.1
-
30
-
-
0000050242
-
Detection of free radicals generated during enzymic oxidations by the initiation of sulfite oxidation
-
I. Fridovich, and P. Handler Detection of free radicals generated during enzymic oxidations by the initiation of sulfite oxidation J. Biol. Chem. 236 1961 1836 1840
-
(1961)
J. Biol. Chem.
, vol.236
, pp. 1836-1840
-
-
Fridovich, I.1
Handler, P.2
-
31
-
-
0035929367
-
The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2
-
M.L. Genova, B. Ventura, G. Giuliano, C. Bovina, G. Formiggini, C.G. Parenti, and G. Lenaz The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2 FEBS Lett. 505 2001 364 368
-
(2001)
FEBS Lett.
, vol.505
, pp. 364-368
-
-
Genova, M.L.1
Ventura, B.2
Giuliano, G.3
Bovina, C.4
Formiggini, G.5
Parenti, C.G.6
Lenaz, G.7
-
32
-
-
3142749712
-
Long-lived Drosophila with overexpressed dFOXO in adult fat body
-
M.E. Giannakou, M. Goss, M.A. Junger, E. Hafen, S.J. Leevers, and L. Partridge Long-lived Drosophila with overexpressed dFOXO in adult fat body Science 305 2004 361
-
(2004)
Science
, vol.305
, pp. 361
-
-
Giannakou, M.E.1
Goss, M.2
Junger, M.A.3
Hafen, E.4
Leevers, S.J.5
Partridge, L.6
-
33
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
D. Harman Aging: a theory based on free radical and radiation chemistry J. Gerontol. 11 1956 298 300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
34
-
-
2942615439
-
Mitochondrial oxidative stress can lead to nuclear hypermutability
-
P. Hartman, R. Ponder, H.H. Lo, and N. Ishii Mitochondrial oxidative stress can lead to nuclear hypermutability Mech. Ageing Dev. 125 2004 417 420
-
(2004)
Mech. Ageing Dev.
, vol.125
, pp. 417-420
-
-
Hartman, P.1
Ponder, R.2
Lo, H.H.3
Ishii, N.4
-
35
-
-
2442649129
-
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors
-
W. He, F.J. Miao, D.C. Lin, R.T. Schwandner, Z. Wang, J. Gao, J.L. Chen, H. Tian, and L. Ling Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors Nature 429 2004 188 193
-
(2004)
Nature
, vol.429
, pp. 188-193
-
-
He, W.1
Miao, F.J.2
Lin, D.C.3
Schwandner, R.T.4
Wang, Z.5
Gao, J.6
Chen, J.L.7
Tian, H.8
Ling, L.9
-
36
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
M. Holzenberger, J. Dupont, B. Ducos, P. Leneuve, A. Geloen, P.C. Even, P. Cervera, and Y. Le Bouc IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice Nature 421 2003 182 187
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Even, P.C.6
Cervera, P.7
Le Bouc, Y.8
-
37
-
-
3543062946
-
Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster
-
A.J. Hulbert, D.J. Clancy, W. Mair, B.P. Braeckman, D. Gems, and L. Partridge Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster Exp. Gerontol. 39 2004 1137 1143
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 1137-1143
-
-
Hulbert, A.J.1
Clancy, D.J.2
Mair, W.3
Braeckman, B.P.4
Gems, D.5
Partridge, L.6
-
38
-
-
0032514466
-
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
-
N. Ishii, M. Fujii, P.S. Hartman, M. Tsuda, K. Yasuda, N. Senoo-Matsuda, S. Yanase, D. Ayusawa, and K. Suzuki A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes Nature 394 1998 694 697
-
(1998)
Nature
, vol.394
, pp. 694-697
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
39
-
-
0034769530
-
Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans
-
T.E. Johnson, E. de Castro, S. Hegi de Castro, J. Cypser, S. Henderson, and P. Tedesco Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans Exp. Gerontol. 36 2001 1609 1617
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 1609-1617
-
-
Johnson, T.E.1
De Castro, E.2
Hegi De Castro, S.3
Cypser, J.4
Henderson, S.5
Tedesco, P.6
-
40
-
-
0346688697
-
NADH enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP): Applications to enzyme and mitochondrial reaction kinetics, in vitro
-
F. Joubert, H.M. Fales, H. Wen, C.A. Combs, and R.S. Balaban NADH enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP): applications to enzyme and mitochondrial reaction kinetics, in vitro Biophys. J. 86 2004 629 645
-
(2004)
Biophys. J.
, vol.86
, pp. 629-645
-
-
Joubert, F.1
Fales, H.M.2
Wen, H.3
Combs, C.A.4
Balaban, R.S.5
-
41
-
-
11144245002
-
Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1
-
E.B. Kayser, M.M. Sedensky, P.G. Morgan, and C.L. Hoppel Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1 J. Biol. Chem. 279 2004 54479 54486
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54479-54486
-
-
Kayser, E.B.1
Sedensky, M.M.2
Morgan, P.G.3
Hoppel, C.L.4
-
42
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
G.J. Kops, T.B. Dansen, P.E. Polderman, I. Saarloos, K.W. Wirtz, P.J. Coffer, T.T. Huang, J.L. Bos, R.H. Medema, and B.M. Burgering Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress Nature 419 2002 316 321
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
Huang, T.T.7
Bos, J.L.8
Medema, R.H.9
Burgering, B.M.10
-
43
-
-
0036903625
-
Complex I-mediated reactive oxygen species generation: Modulation by cytochrome c and NAD(P)+ oxidation-reduction state
-
Y. Kushnareva, A.N. Murphy, and A. Andreyev Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state Biochem. J. 368 2002 545 553
-
(2002)
Biochem. J.
, vol.368
, pp. 545-553
-
-
Kushnareva, Y.1
Murphy, A.N.2
Andreyev, A.3
-
44
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
J.D. Lambeth NOX enzymes and the biology of reactive oxygen Nat. Rev. Immunol. 4 2004 181 189
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
45
-
-
2442719045
-
Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster
-
G.N. Landis, D. Abdueva, D. Skvortsov, J. Yang, B.E. Rabin, J. Carrick, S. Tavare, and J. Tower Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster Proc. Natl. Acad. Sci. USA 101 2004 7663 7668
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7663-7668
-
-
Landis, G.N.1
Abdueva, D.2
Skvortsov, D.3
Yang, J.4
Rabin, B.E.5
Carrick, J.6
Tavare, S.7
Tower, J.8
-
46
-
-
0037016442
-
Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q
-
P.L. Larsen, and C.F. Clarke Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q Science 295 2002 120 123
-
(2002)
Science
, vol.295
, pp. 120-123
-
-
Larsen, P.L.1
Clarke, C.F.2
-
47
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
A.C. Lee, B.E. Fenster, H. Ito, K. Takeda, N.S. Bae, T. Hirai, Z.X. Yu, V.J. Ferrans, B.H. Howard, and T. Finkel Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species J. Biol. Chem. 274 1999 7936 7940
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
48
-
-
0037466652
-
DAF-16 target genes that control C. elegans life-span and metabolism
-
S.S. Lee, S. Kennedy, A.C. Tolonen, and G. Ruvkun DAF-16 target genes that control C. elegans life-span and metabolism Science 300 2003 644 647
-
(2003)
Science
, vol.300
, pp. 644-647
-
-
Lee, S.S.1
Kennedy, S.2
Tolonen, A.C.3
Ruvkun, G.4
-
49
-
-
0037228016
-
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
-
S.S. Lee, R.Y. Lee, A.G. Fraser, R.S. Kamath, J. Ahringer, and G. Ruvkun A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity Nat. Genet. 33 2003 40 48
-
(2003)
Nat. Genet.
, vol.33
, pp. 40-48
-
-
Lee, S.S.1
Lee, R.Y.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Ruvkun, G.6
-
50
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Y.J. Lin, L. Seroude, and S. Benzer Extended life-span and stress resistance in the Drosophila mutant methuselah Science 282 1998 943 946
-
(1998)
Science
, vol.282
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
51
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
S.J. Lin, M. Kaeberlein, A.A. Andalis, L.A. Sturtz, P.A. Defossez, V.C. Culotta, G.R. Fink, and L. Guarente Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration Nature 418 2002 344 348
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
52
-
-
0036319021
-
Generation of reactive oxygen species by the mitochondrial electron transport chain
-
Y. Liu, G. Fiskum, and D. Schubert Generation of reactive oxygen species by the mitochondrial electron transport chain J. Neurochem. 80 2002 780 787
-
(2002)
J. Neurochem.
, vol.80
, pp. 780-787
-
-
Liu, Y.1
Fiskum, G.2
Schubert, D.3
-
53
-
-
0000466588
-
Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria
-
G. Loschen, L. Flohe, and B. Chance Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria FEBS Lett. 18 1971 261 264
-
(1971)
FEBS Lett.
, vol.18
, pp. 261-264
-
-
Loschen, G.1
Flohe, L.2
Chance, B.3
-
54
-
-
0035382613
-
Cytochrome C oxidase and the regulation of oxidative phosphorylation
-
B. Ludwig, E. Bender, S. Arnold, M. Huttemann, I. Lee, and B. Kadenbach Cytochrome C oxidase and the regulation of oxidative phosphorylation ChemBioChem 2 2001 392 403
-
(2001)
ChemBioChem
, vol.2
, pp. 392-403
-
-
Ludwig, B.1
Bender, E.2
Arnold, S.3
Huttemann, M.4
Lee, I.5
Kadenbach, B.6
-
55
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
J. Luo, A.Y. Nikolaev, S. Imai, D. Chen, F. Su, A. Shiloh, L. Guarente, and W. Gu Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 107 2001 137 148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
56
-
-
0242552555
-
Influence of induced reactive oxygen species in p53-mediated cell fate decisions
-
S. Macip, M. Igarashi, P. Berggren, J. Yu, S.W. Lee, and S.A. Aaronson Influence of induced reactive oxygen species in p53-mediated cell fate decisions Mol. Cell. Biol. 23 2003 8576 8585
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8576-8585
-
-
MacIp, S.1
Igarashi, M.2
Berggren, P.3
Yu, J.4
Lee, S.W.5
Aaronson, S.A.6
-
57
-
-
1842440378
-
Is defective electron transport at the hub of aging?
-
E. Maklashina, and B.A. Ackrell Is defective electron transport at the hub of aging? Aging Cell 3 2004 21 27
-
(2004)
Aging Cell
, vol.3
, pp. 21-27
-
-
Maklashina, E.1
Ackrell, B.A.2
-
58
-
-
0037452882
-
Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies
-
J.H. Marden, B. Rogina, K.L. Montooth, and S.L. Helfand Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies Proc. Natl. Acad. Sci. USA 100 2003 3369 3373
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3369-3373
-
-
Marden, J.H.1
Rogina, B.2
Montooth, K.L.3
Helfand, S.L.4
-
59
-
-
0842267618
-
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging
-
S.A. McCarroll, C.T. Murphy, S. Zou, S.D. Pletcher, C.S. Chin, Y.N. Jan, C. Kenyon, C.I. Bargmann, and H. Li Comparing genomic expression patterns across species identifies shared transcriptional profile in aging Nat. Genet. 36 2004 197 204
-
(2004)
Nat. Genet.
, vol.36
, pp. 197-204
-
-
McCarroll, S.A.1
Murphy, C.T.2
Zou, S.3
Pletcher, S.D.4
Chin, C.S.5
Jan, Y.N.6
Kenyon, C.7
Bargmann, C.I.8
Li, H.9
-
60
-
-
0014691242
-
Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
-
J.M. McCord, and I. Fridovich Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein) J. Biol. Chem. 244 1969 6049 6055
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
61
-
-
0042631524
-
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
-
J. McElwee, K. Bubb, and J.H. Thomas Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16 Aging Cell 2 2003 111 121
-
(2003)
Aging Cell
, vol.2
, pp. 111-121
-
-
McElwee, J.1
Bubb, K.2
Thomas, J.H.3
-
62
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
E. Migliaccio, M. Giorgio, S. Mele, G. Pelicci, P. Reboldi, P.P. Pandolfi, L. Lanfrancone, and P.G. Pelicci The p66shc adaptor protein controls oxidative stress response and life span in mammals Nature 402 1999 309 313
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
63
-
-
0017138542
-
Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster
-
J. Miquel, P.R. Lundgren, K.G. Bensch, and H. Atlan Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster Mech. Ageing Dev. 5 1976 347 370
-
(1976)
Mech. Ageing Dev.
, vol.5
, pp. 347-370
-
-
Miquel, J.1
Lundgren, P.R.2
Bensch, K.G.3
Atlan, H.4
-
64
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
C.T. Murphy, S.A. McCarroll, C.I. Bargmann, A. Fraser, R.S. Kamath, J. Ahringer, H. Li, and C. Kenyon Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans Nature 424 2003 277 283
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
65
-
-
0037452461
-
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
C. Napoli, I. Martin-Padura, F. de Nigris, M. Giorgio, G. Mansueto, P. Somma, M. Condorelli, G. Sica, G. De Rosa, and P. Pelicci Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet Proc. Natl. Acad. Sci. USA 100 2003 2112 2116
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2112-2116
-
-
Napoli, C.1
Martin-Padura, I.2
De Nigris, F.3
Giorgio, M.4
Mansueto, G.5
Somma, P.6
Condorelli, M.7
Sica, G.8
De Rosa, G.9
Pelicci, P.10
-
66
-
-
0037192473
-
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
-
S. Nemoto, and T. Finkel Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway Science 295 2002 2450 2452
-
(2002)
Science
, vol.295
, pp. 2450-2452
-
-
Nemoto, S.1
Finkel, T.2
-
67
-
-
0033826520
-
Role for mitochondrial oxidants as regulators of cellular metabolism
-
S. Nemoto, K. Takeda, Z.X. Yu, V.J. Ferrans, and T. Finkel Role for mitochondrial oxidants as regulators of cellular metabolism Mol. Cell. Biol. 20 2000 7311 7318
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7311-7318
-
-
Nemoto, S.1
Takeda, K.2
Yu, Z.X.3
Ferrans, V.J.4
Finkel, T.5
-
68
-
-
2942564591
-
Sirtuins: Sir2-related NAD-dependent protein deacetylases
-
B.J. North, and E. Verdin Sirtuins: Sir2-related NAD-dependent protein deacetylases Genome Biol. 5 2004 224
-
(2004)
Genome Biol.
, vol.5
, pp. 224
-
-
North, B.J.1
Verdin, E.2
-
69
-
-
0026754226
-
Intrinsic signal changes accompanying sensory stimulation: Functional brain mapping with magnetic resonance imaging
-
S. Ogawa, D.W. Tank, R. Menon, J.M. Ellermann, S.G. Kim, H. Merkle, and K. Ugurbil Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging Proc. Natl. Acad. Sci. USA 89 1992 5951 5955
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5951-5955
-
-
Ogawa, S.1
Tank, D.W.2
Menon, R.3
Ellermann, J.M.4
Kim, S.G.5
Merkle, H.6
Ugurbil, K.7
-
70
-
-
0020491044
-
The cytochrome c peroxidase activity of cytochrome oxidase
-
Y. Orii The cytochrome c peroxidase activity of cytochrome oxidase J. Biol. Chem. 257 1982 9246 9248
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 9246-9248
-
-
Orii, Y.1
-
71
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
W.C. Orr, and R.S. Sohal Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster Science 263 1994 1128 1130
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
72
-
-
0038712734
-
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster
-
W.C. Orr, R.J. Mockett, J.J. Benes, and R.S. Sohal Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster J. Biol. Chem. 278 2003 26418 26422
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26418-26422
-
-
Orr, W.C.1
Mockett, R.J.2
Benes, J.J.3
Sohal, R.S.4
-
73
-
-
2942584910
-
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential
-
F. Orsini, E. Migliaccio, M. Moroni, C. Contursi, V.A. Raker, D. Piccini, I. Martin-Padura, G. Pelliccia, M. Trinei, and M. Bono The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential J. Biol. Chem. 279 2004 25689 25695
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25689-25695
-
-
Orsini, F.1
Migliaccio, E.2
Moroni, M.3
Contursi, C.4
Raker, V.A.5
Piccini, D.6
Martin-Padura, I.7
Pelliccia, G.8
Trinei, M.9
Bono, M.10
-
74
-
-
0017405185
-
Low oxygen concentration extends the lifespan of cultured human diploid cells
-
L. Packer, and K. Fuehr Low oxygen concentration extends the lifespan of cultured human diploid cells Nature 267 1977 423 425
-
(1977)
Nature
, vol.267
, pp. 423-425
-
-
Packer, L.1
Fuehr, K.2
-
75
-
-
0031864164
-
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
-
T.L. Parkes, A.J. Elia, D. Dickinson, A.J. Hilliker, J.P. Phillips, and G.L. Boulianne Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons Nat. Genet. 19 1998 171 174
-
(1998)
Nat. Genet.
, vol.19
, pp. 171-174
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Phillips, J.P.5
Boulianne, G.L.6
-
76
-
-
0003693103
-
-
University of London Press London
-
R. Pearl The Rate of Living 1928 University of London Press London
-
(1928)
The Rate of Living
-
-
Pearl, R.1
-
77
-
-
0348107409
-
The TCA cycle and tumorigenesis: The examples of fumarate hydratase and succinate dehydrogenase
-
P.J. Pollard, N.C. Wortham, and I.P. Tomlinson The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase Ann. Med. 35 2003 632 639
-
(2003)
Ann. Med.
, vol.35
, pp. 632-639
-
-
Pollard, P.J.1
Wortham, N.C.2
Tomlinson, I.P.3
-
78
-
-
4344566857
-
Murine models of life span extension
-
August 4, 2004
-
Quarrie, J.K., and Riabowol, K.T. (2004). Murine models of life span extension. Sci. Aging Knowledge Environ. 31, August 4, 2004, re5.
-
(2004)
Sci. Aging Knowledge Environ.
, vol.31
-
-
Quarrie, J.K.1
Riabowol, K.T.2
-
79
-
-
0025719056
-
Detection of catalase in rat heart mitochondria
-
R. Radi, J.F. Turrens, L.Y. Chang, K.M. Bush, J.D. Crapo, and B.A. Freeman Detection of catalase in rat heart mitochondria J. Biol. Chem. 266 1991 22028 22034
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22028-22034
-
-
Radi, R.1
Turrens, J.F.2
Chang, L.Y.3
Bush, K.M.4
Crapo, J.D.5
Freeman, B.A.6
-
80
-
-
0041440219
-
A metabolic model for life span determination in Caenorhabditis elegans
-
S. Rea, and T.E. Johnson A metabolic model for life span determination in Caenorhabditis elegans Dev. Cell 5 2003 197 203
-
(2003)
Dev. Cell
, vol.5
, pp. 197-203
-
-
Rea, S.1
Johnson, T.E.2
-
81
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
C. Richter, J.W. Park, and B.N. Ames Normal oxidative damage to mitochondrial and nuclear DNA is extensive Proc. Natl. Acad. Sci. USA 85 1988 6465 6467
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
82
-
-
0022233869
-
Organization of Krebs tricarboxylic acid cycle enzymes in mitochondria
-
J.B. Robinson Jr., and P.A. Srere Organization of Krebs tricarboxylic acid cycle enzymes in mitochondria J. Biol. Chem. 260 1985 10800 10805
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 10800-10805
-
-
Robinson Jr., J.B.1
Srere, P.A.2
-
83
-
-
0034671596
-
Extended life-span conferred by cotransporter gene mutations in Drosophila
-
B. Rogina, R.A. Reenan, S.P. Nilsen, and S.L. Helfand Extended life-span conferred by cotransporter gene mutations in Drosophila Science 290 2000 2137 2140
-
(2000)
Science
, vol.290
, pp. 2137-2140
-
-
Rogina, B.1
Reenan, R.A.2
Nilsen, S.P.3
Helfand, S.L.4
-
84
-
-
0035834789
-
A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans
-
N. Senoo-Matsuda, K. Yasuda, M. Tsuda, T. Ohkubo, S. Yoshimura, H. Nakazawa, P.S. Hartman, and N. Ishii A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans J. Biol. Chem. 276 2001 41553 41558
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41553-41558
-
-
Senoo-Matsuda, N.1
Yasuda, K.2
Tsuda, M.3
Ohkubo, T.4
Yoshimura, S.5
Nakazawa, H.6
Hartman, P.S.7
Ishii, N.8
-
85
-
-
0037470062
-
Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening
-
V. Serra, T. von Zglinicki, M. Lorenz, and G. Saretzki Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening J. Biol. Chem. 278 2003 6824 6830
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6824-6830
-
-
Serra, V.1
Von Zglinicki, T.2
Lorenz, M.3
Saretzki, G.4
-
86
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
M. Serrano, A.W. Lin, M.E. McCurrach, D. Beach, and S.W. Lowe Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a Cell 88 1997 593 602
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
87
-
-
0345600235
-
Redox regulation of germline and vulval development in Caenorhabditis elegans
-
Y. Shibata, R. Branicky, I.O. Landaverde, and S. Hekimi Redox regulation of germline and vulval development in Caenorhabditis elegans Science 302 2003 1779 1782
-
(2003)
Science
, vol.302
, pp. 1779-1782
-
-
Shibata, Y.1
Branicky, R.2
Landaverde, I.O.3
Hekimi, S.4
-
89
-
-
7044239977
-
Uncoupled and surviving: Individual mice with high metabolism have greater mitochondrial uncoupling and live longer
-
J.R. Speakman, D.A. Talbot, C. Selman, S. Snart, J.S. McLaren, P. Redman, E. Krol, D.M. Jackson, M.S. Johnson, and M.D. Brand Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer Aging Cell 3 2004 87 95
-
(2004)
Aging Cell
, vol.3
, pp. 87-95
-
-
Speakman, J.R.1
Talbot, D.A.2
Selman, C.3
Snart, S.4
McLaren, J.S.5
Redman, P.6
Krol, E.7
Jackson, D.M.8
Johnson, M.S.9
Brand, M.D.10
-
90
-
-
0034693690
-
Are mitochondria a permanent source of reactive oxygen species?
-
K. Staniek, and H. Nohl Are mitochondria a permanent source of reactive oxygen species? Biochim. Biophys. Acta 1460 2000 268 275
-
(2000)
Biochim. Biophys. Acta
, vol.1460
, pp. 268-275
-
-
Staniek, K.1
Nohl, H.2
-
91
-
-
0037160091
-
Topology of superoxide production from different sites in the mitochondrial electron transport chain
-
J. St-Pierre, J.A. Buckingham, S.J. Roebuck, and M.D. Brand Topology of superoxide production from different sites in the mitochondrial electron transport chain J. Biol. Chem. 277 2002 44784 44790
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44784-44790
-
-
St-Pierre, J.1
Buckingham, J.A.2
Roebuck, S.J.3
Brand, M.D.4
-
92
-
-
0032908347
-
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies
-
J. Sun, and J. Tower FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies Mol. Cell. Biol. 19 1999 216 228
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 216-228
-
-
Sun, J.1
Tower, J.2
-
93
-
-
0037336905
-
Characterization of the human heart mitochondrial proteome
-
S.W. Taylor, E. Fahy, B. Zhang, G.M. Glenn, D.E. Warnock, S. Wiley, A.N. Murphy, S.P. Gaucher, R.A. Capaldi, B.W. Gibson, and S.S. Ghosh Characterization of the human heart mitochondrial proteome Nat. Biotechnol. 21 2003 281 286
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 281-286
-
-
Taylor, S.W.1
Fahy, E.2
Zhang, B.3
Glenn, G.M.4
Warnock, D.E.5
Wiley, S.6
Murphy, A.N.7
Gaucher, S.P.8
Capaldi, R.A.9
Gibson, B.W.10
Ghosh, S.S.11
-
94
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
A. Trifunovic, A. Wredenberg, M. Falkenberg, J.N. Spelbrink, A.T. Rovio, C.E. Bruder, Y.M. Bohlooly, S. Gidlof, A. Oldfors, and R. Wibom Premature ageing in mice expressing defective mitochondrial DNA polymerase Nature 429 2004 417 423
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
-
95
-
-
85047695800
-
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
-
M. Trinei, M. Giorgio, A. Cicalese, S. Barozzi, A. Ventura, E. Migliaccio, E. Milia, I.M. Padura, V.A. Raker, and M. Maccarana A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis Oncogene 21 2002 3872 3878
-
(2002)
Oncogene
, vol.21
, pp. 3872-3878
-
-
Trinei, M.1
Giorgio, M.2
Cicalese, A.3
Barozzi, S.4
Ventura, A.5
Migliaccio, E.6
Milia, E.7
Padura, I.M.8
Raker, V.A.9
MacCarana, M.10
-
96
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
J.F. Turrens Mitochondrial formation of reactive oxygen species J. Physiol. 552 2003 335 344
-
(2003)
J. Physiol.
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
97
-
-
0020335388
-
Hyperoxia increases H2O2 release by lung mitochondria and microsomes
-
J.F. Turrens, B.A. Freeman, and J.D. Crapo Hyperoxia increases H2O2 release by lung mitochondria and microsomes Arch. Biochem. Biophys. 217 1982 411 421
-
(1982)
Arch. Biochem. Biophys.
, vol.217
, pp. 411-421
-
-
Turrens, J.F.1
Freeman, B.A.2
Crapo, J.D.3
-
98
-
-
0021996572
-
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
-
J.F. Turrens, A. Alexandre, and A.L. Lehninger Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria Arch. Biochem. Biophys. 237 1985 408 414
-
(1985)
Arch. Biochem. Biophys.
, vol.237
, pp. 408-414
-
-
Turrens, J.F.1
Alexandre, A.2
Lehninger, A.L.3
-
99
-
-
0030087733
-
Rate of aerobic metabolism and superoxide production rate potential in the nematode Caenorhabditis elegans
-
J.R. Vanfleteren, and A. De Vreese Rate of aerobic metabolism and superoxide production rate potential in the nematode Caenorhabditis elegans J. Exp. Zool. 274 1996 93 100
-
(1996)
J. Exp. Zool.
, vol.274
, pp. 93-100
-
-
Vanfleteren, J.R.1
De Vreese, A.2
-
100
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
H. Van Remmen, Y. Ikeno, M. Hamilton, M. Pahlavani, N. Wolf, S.R. Thorpe, N.L. Alderson, J.W. Baynes, C.J. Epstein, and T.T. Huang Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging Physiol. Genomics 16 2003 29 37
-
(2003)
Physiol. Genomics
, vol.16
, pp. 29-37
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
Pahlavani, M.4
Wolf, N.5
Thorpe, S.R.6
Alderson, N.L.7
Baynes, J.W.8
Epstein, C.J.9
Huang, T.T.10
-
101
-
-
0024515401
-
Developmental regulation of energy metabolism in Caenorhabditis elegans
-
W.G. Wadsworth, and D.L. Riddle Developmental regulation of energy metabolism in Caenorhabditis elegans Dev. Biol. 132 1989 167 173
-
(1989)
Dev. Biol.
, vol.132
, pp. 167-173
-
-
Wadsworth, W.G.1
Riddle, D.L.2
-
102
-
-
3142668925
-
Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl
-
D.W. Walker, and S. Benzer Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl Proc. Natl. Acad. Sci. USA 101 2004 10290 10295
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10290-10295
-
-
Walker, D.W.1
Benzer, S.2
-
103
-
-
0242362732
-
JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila
-
M.C. Wang, D. Bohmann, and H. Jasper JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila Dev. Cell 5 2003 811 816
-
(2003)
Dev. Cell
, vol.5
, pp. 811-816
-
-
Wang, M.C.1
Bohmann, D.2
Jasper, H.3
-
104
-
-
0037157824
-
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
-
E. Werner, and Z. Werb Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases J. Cell Biol. 158 2002 357 368
-
(2002)
J. Cell Biol.
, vol.158
, pp. 357-368
-
-
Werner, E.1
Werb, Z.2
-
105
-
-
0023759565
-
The potential diagram for oxygen at pH 7
-
P.M. Wood The potential diagram for oxygen at pH 7 Biochem. J. 253 1988 287 289
-
(1988)
Biochem. J.
, vol.253
, pp. 287-289
-
-
Wood, P.M.1
-
106
-
-
10344229445
-
Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
-
C. Wu, I. Miloslavskaya, S. Demontis, R. Maestro, and K. Galaktionov Regulation of cellular response to oncogenic and oxidative stress by Seladin-1 Nature 432 2004 640 645
-
(2004)
Nature
, vol.432
, pp. 640-645
-
-
Wu, C.1
Miloslavskaya, I.2
Demontis, S.3
Maestro, R.4
Galaktionov, K.5
-
107
-
-
0037418550
-
The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: The secret unlocked
-
T. Yagi, and A. Matsuno-Yagi The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: the secret unlocked Biochemistry 42 2003 2266 2274
-
(2003)
Biochemistry
, vol.42
, pp. 2266-2274
-
-
Yagi, T.1
Matsuno-Yagi, A.2
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