Subcellular targets of cisplatin cytotoxicity: An integrated view

Pharmacology and Therapeutics

Volumn 136, Issue 1, 2012, Pages 35-55

  Sancho Martínez, Sandra M ^b,c,d   Prieto García, Laura ^b,c   Prieto, Marta ^b,c,d   López Novoa, José M ^b,c,d   López Hernández, Francisco J ^a,b,c,d  

^a HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^b INSTITUTO DE INVESTIGACIÓN BIOMÉDICA DE SALAMANCA IBSAL   (Spain)

^c UNIVERSITY OF SALAMANCA   (Spain)

^d Section of Nephrology   (Spain)

Author keywords

Apoptosis; Bcl 2; Cisplatin; Cytotoxicity; Mitochondria; Necrosis

Indexed keywords

CARBOPLATIN; CISPLATIN; OXALIPLATIN;

APOPTOSIS; CELL DEATH; CELL INTERACTION; CELL MEMBRANE; CELL MIGRATION; CELL NUCLEUS; CELL ORGANELLE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CYTOSKELETON; CYTOTOXICITY; DNA DAMAGE; DRUG BINDING; DRUG MECHANISM; DRUG TARGETING; DRUG TRANSPORT; ENDOPLASMIC RETICULUM STRESS; GENOTOXICITY; HUMAN; INNER EAR; KIDNEY TUBULE; LYSOSOME; MACROMOLECULE; MITOCHONDRION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CELL NUCLEUS; CISPLATIN; CYTOSKELETON; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; HUMANS; LYSOSOMES; MITOCHONDRIA;

EID: 84865576732     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.07.003     Document Type: Review

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