-
1
-
-
77952952903
-
The role of Bcl-2 family proteins in chronic lymphocytic leukaemia
-
Buggins AG, Pepper CJ. The role of Bcl-2 family proteins in chronic lymphocytic leukaemia. Leuk Res. 2010; 34(7):837-42.
-
(2010)
Leuk Res
, vol.34
, Issue.7
, pp. 837-842
-
-
Buggins, A.G.1
Pepper, C.J.2
-
2
-
-
28944432804
-
Multidrug resistance/ P-glycoprotein and breast cancer: Review and meta-analysis
-
Clarke R, Leonessa F, Trock B. Multidrug resistance/ P-glycoprotein and breast cancer: review and meta-analysis. Semin Oncol. 2005; 32(6 Suppl 7):S9-15.
-
(2005)
Semin Oncol
, vol.32
, Issue.6 SUPPL 7
-
-
Clarke, R.1
Leonessa, F.2
Trock, B.3
-
3
-
-
62149113710
-
Relevance of multidrug resistance in the age of targeted therapy
-
Türk D, Szakács G. Relevance of multidrug resistance in the age of targeted therapy. Curr Opin Drug Discov Devel. 2009; 12(2):246-52.
-
(2009)
Curr Opin Drug Discov Devel
, vol.12
, Issue.2
, pp. 246-252
-
-
Türk, D.1
Szakács, G.2
-
4
-
-
2542491777
-
The role of ABC transporters in drug resistance, metabolism and toxicity
-
Glavinas, H., Krajcsi, P., Cserepes, J., Sarkadi, B. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv. 2004; 1(1) 27-42.
-
(2004)
Curr Drug Deliv
, vol.1
, Issue.1
, pp. 27-42
-
-
Glavinas, H.1
Krajcsi, P.2
Cserepes, J.3
Sarkadi, B.4
-
5
-
-
33646371709
-
Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drug-resistant tumors: Current views and new therapeutic prospective
-
Roberti A, La Sala D, Cinti C. Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drug-resistant tumors: current views and new therapeutic prospective. J Cell Physiol. 2006; 207 (3) 571-81.
-
(2006)
J Cell Physiol
, vol.207
, Issue.3
, pp. 571-581
-
-
Roberti, A.1
la Sala, D.2
Cinti, C.3
-
6
-
-
39049148397
-
Cellular FLICE-like inhibitory protein (C-FLIP): A novel target for cancer therapy
-
Safa AR, Day TW, Wu CH. Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy. Curr Cancer Drug Targets. 2008; 8 (1):37-46.
-
(2008)
Curr Cancer Drug Targets
, vol.8
, Issue.1
, pp. 37-46
-
-
Safa, A.R.1
Day, T.W.2
Wu, C.H.3
-
7
-
-
34248584499
-
Phosphorylation of RNA helicase A by DNA-dependent protein kinase is indispensable for expression of the MDR1 gene product P-glycoprotein in multidrug-resistant human leukemia cells
-
Zhong X, Safa AR. Phosphorylation of RNA helicase A by DNA-dependent protein kinase is indispensable for expression of the MDR1 gene product P-glycoprotein in multidrug-resistant human leukemia cells. Biochemistry. 2007; 46 (19):5766-75.
-
(2007)
Biochemistry
, vol.46
, Issue.19
, pp. 5766-5775
-
-
Zhong, X.1
Safa, A.R.2
-
8
-
-
77950672853
-
The structure and functions of P-glycoprotein
-
Li Y, Yuan H, Yang K, Xu W, Tang W, Li X. The structure and functions of P-glycoprotein. Curr Med Chem. 2010; 17(8):786-800.
-
(2010)
Curr Med Chem
, vol.17
, Issue.8
, pp. 786-800
-
-
Li, Y.1
Yuan, H.2
Yang, K.3
Xu, W.4
Tang, W.5
Li, X.6
-
9
-
-
1142274315
-
Apoptosis in cancer--implications for therapy
-
Schulze-Bergkamen H, Krammer PH. Apoptosis in cancer--implications for therapy. Semin Oncol. 2004; 31(1):90-119.
-
(2004)
Semin Oncol
, vol.31
, Issue.1
, pp. 90-119
-
-
Schulze-Bergkamen, H.1
Krammer, P.H.2
-
10
-
-
77949436262
-
The role of apoptosis in cancer development and treatment: Focusing on the development and treatment of hematologic malignancies
-
Zivny J, Klener P Jr, Pytlik R, Andera L. The role of apoptosis in cancer development and treatment: focusing on the development and treatment of hematologic malignancies. Curr Pharm Des. 2010; 16(1):11-33.
-
(2010)
Curr Pharm Des
, vol.16
, Issue.1
, pp. 11-33
-
-
Zivny, J.1
Klener Jr., P.2
Pytlik, R.3
Andera, L.4
-
11
-
-
43449108570
-
Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia
-
Del Poeta G, Bruno A, Del Principe MI, Venditti A, Maurillo L, Buccisano F, Stasi R, Neri B, Luciano F, Siniscalchi A, de Fabritiis P, Amadori S. Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia. Curr Cancer Drug Targets. 2008; 8(3):207-22.
-
(2008)
Curr Cancer Drug Targets
, vol.8
, Issue.3
, pp. 207-222
-
-
del Poeta, G.1
Bruno, A.2
del Principe, M.I.3
Venditti, A.4
Maurillo, L.5
Buccisano, F.6
Stasi, R.7
Neri, B.8
Luciano, F.9
Siniscalchi, A.10
de Fabritiis, P.11
Amadori, S.12
-
12
-
-
43249093771
-
Therapeutic targeting of death pathways in cancer: Mechanisms for activating cell death in cancer cells
-
Tan TT, White E. Therapeutic targeting of death pathways in cancer: mechanisms for activating cell death in cancer cells. Adv Exp Med Biol. 2008; 615:81-104.
-
(2008)
Adv Exp Med Biol
, vol.615
, pp. 81-104
-
-
Tan, T.T.1
White, E.2
-
13
-
-
62449166171
-
Is TRAIL the holy grail of cancer therapy?
-
Is TRAIL the holy grail of cancer therapy? Newsom-Davis T, Prieske S, Walczak H. Apoptosis 2009; 14(4): 607-23.
-
(2009)
Apoptosis
, vol.14
, Issue.4
, pp. 607-623
-
-
Newsom-Davis, T.1
Prieske, S.2
Walczak, H.3
-
14
-
-
77649181792
-
Death receptors: Targets for cancer therapy
-
Mahmood Z, Shukla Y. Death receptors: targets for cancer therapy. Exp Cell Res. 2010; 316(6): 887-99.
-
(2010)
Exp Cell Res
, vol.316
, Issue.6
, pp. 887-899
-
-
Mahmood, Z.1
Shukla, Y.2
-
15
-
-
70350057568
-
Apoptosis in cancer: Key molecular signaling pathways and therapy targets
-
Burz C, Berindan-Neagoe I, Balacescu O, Irimie A. Apoptosis in cancer: key molecular signaling pathways and therapy targets. Acta Oncol. 2009; 48(6):811-21.
-
(2009)
Acta Oncol
, vol.48
, Issue.6
, pp. 811-821
-
-
Burz, C.1
Berindan-Neagoe, I.2
Balacescu, O.3
Irimie, A.4
-
16
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
Ashkenazi, A. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer. 2002; 2(6):420-30.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.6
, pp. 420-430
-
-
Ashkenazi, A.1
-
17
-
-
56549112480
-
C-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells
-
Day TW, Huang S, Safa AR. c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells. Biochem Pharmacol. 2008; 76(12):1694-704.
-
(2008)
Biochem Pharmacol
, vol.76
, Issue.12
, pp. 1694-1704
-
-
Day, T.W.1
Huang, S.2
Safa, A.R.3
-
18
-
-
77649341399
-
Playing the DISC: Turning on TRAIL death receptor-mediated apoptosis in cancer
-
Pennarun B, Meijer A, de Vries EG, Kleibeuker JH, Kruyt F, de Jong S. Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancer. Biochim Biophys Acta. 2010; 1805 (2):123-40.
-
(2010)
Biochim Biophys Acta
, vol.1805
, Issue.2
, pp. 123-140
-
-
Pennarun, B.1
Meijer, A.2
de Vries, E.G.3
Kleibeuker, J.H.4
Kruyt, F.5
de Jong, S.6
-
19
-
-
33744517489
-
Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis
-
Muppidi JR, Lobito AA, Ramaswamy M, Yang JK, Wang L, Wu H, Siegel RM. Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis. Cell Death Differ. 2006; 13(10):1641-50.
-
(2006)
Cell Death Differ
, vol.13
, Issue.10
, pp. 1641-1650
-
-
Muppidi, J.R.1
Lobito, A.A.2
Ramaswamy, M.3
Yang, J.K.4
Wang, L.5
Wu, H.6
Siegel, R.M.7
-
20
-
-
70449491806
-
Emerging role of tumour necrosis factor-related apoptosisinducing ligand (TRAIL) as a key regulator of inflammatory responses
-
Collison A, Foster PS, Mattes J.Emerging role of tumour necrosis factor-related apoptosisinducing ligand (TRAIL) as a key regulator of inflammatory responses. Clin Exp Pharmacol Physiol. 2009; 36(11):1049-53.
-
(2009)
Clin Exp Pharmacol Physiol
, vol.36
, Issue.11
, pp. 1049-1053
-
-
Collison, A.1
Foster, P.S.2
Mattes, J.3
-
21
-
-
34547104357
-
The death receptor DR5 is involved in TRAIL-mediated human osteoclast apoptosis
-
Colucci S, Brunetti G, Cantatore FP, Oranger A, Mori G, Pignataro P, Tamma R, Grassi FR, Zallone A, Grano M. The death receptor DR5 is involved in TRAIL-mediated human osteoclast apoptosis. Apoptosis. 2007; 12(9):1623-32.
-
(2007)
Apoptosis
, vol.12
, Issue.9
, pp. 1623-1632
-
-
Colucci, S.1
Brunetti, G.2
Cantatore, F.P.3
Oranger, A.4
Mori, G.5
Pignataro, P.6
Tamma, R.7
Grassi, F.R.8
Zallone, A.9
Grano, M.10
-
22
-
-
33745658614
-
P-glycoprotein enhances TRAILtriggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5
-
Park SJ, Wu CH, Choi MR, Najafi F, Emami A, Safa AR. P-glycoprotein enhances TRAILtriggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5. Biochem Pharmacol. 2006; 72(3):293-307.
-
(2006)
Biochem Pharmacol
, vol.72
, Issue.3
, pp. 293-307
-
-
Park, S.J.1
Wu, C.H.2
Choi, M.R.3
Najafi, F.4
Emami, A.5
Safa, A.R.6
-
23
-
-
47549090609
-
TRAIL recombinant adenovirus triggers robust apoptosis in multidrug- resistant HL-60/Vinc cells preferentially through death receptor DR5
-
Wu CH, Kao CH, Safa AR. TRAIL recombinant adenovirus triggers robust apoptosis in multidrug- resistant HL-60/Vinc cells preferentially through death receptor DR5. Hum Gene Ther. 2008; 19(7): 731-43.
-
(2008)
Hum Gene Ther
, vol.19
, Issue.7
, pp. 731-743
-
-
Wu, C.H.1
Kao, C.H.2
Safa, A.R.3
-
24
-
-
69249087342
-
Osteoprotegerin production by breast cancer cells is suppressed by dexamethasone and confers resistance against TRAIL-induced apoptosis
-
Rachner TD, Benad P, Rauner M, Goettsch C, Singh SK, Schoppet M, Hofbauer LC. Osteoprotegerin production by breast cancer cells is suppressed by dexamethasone and confers resistance against TRAIL-induced apoptosis. J Cell Biochem. 2009; 108(1):106-16.
-
(2009)
J Cell Biochem
, vol.108
, Issue.1
, pp. 106-116
-
-
Rachner, T.D.1
Benad, P.2
Rauner, M.3
Goettsch, C.4
Singh, S.K.5
Schoppet, M.6
Hofbauer, L.C.7
-
25
-
-
77953726947
-
Inhibition of tissue transglutaminase sensitizes TRAIL-resistant lung cancer cells through upregulation of death receptor 5
-
Frese-Schaper M, Schardt JA, Sakai T, Carboni GL, Schmid RA, Frese S. Inhibition of tissue transglutaminase sensitizes TRAIL-resistant lung cancer cells through upregulation of death receptor 5. FEBS Lett. 2010; 584(13):2867-71.
-
(2010)
FEBS Lett
, vol.584
, Issue.13
, pp. 2867-2871
-
-
Frese-Schaper, M.1
Schardt, J.A.2
Sakai, T.3
Carboni, G.L.4
Schmid, R.A.5
Frese, S.6
-
26
-
-
77950814683
-
HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells
-
Schüler S, Fritsche P, Diersch S, Arlt A, Schmid RM, Saur D, Schneider G. HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells. Mol Cancer. 2010; 9:80.
-
(2010)
Mol Cancer
, vol.9
, pp. 80
-
-
Schüler, S.1
Fritsche, P.2
Diersch, S.3
Arlt, A.4
Schmid, R.M.5
Saur, D.6
Schneider, G.7
-
27
-
-
77951043153
-
The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced apoptosis by activating p8/ CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis
-
Pellerito O, Calvaruso G, Portanova P, De Blasio A, Santulli A, Vento R, Tesoriere G, Giuliano M. The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced apoptosis by activating p8/ CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis. Mol Pharmacol. 2010; 77(5):854-63.
-
(2010)
Mol Pharmacol
, vol.77
, Issue.5
, pp. 854-863
-
-
Pellerito, O.1
Calvaruso, G.2
Portanova, P.3
de Blasio, A.4
Santulli, A.5
Vento, R.6
Tesoriere, G.7
Giuliano, M.8
-
28
-
-
48549103399
-
CAAT/ enhancer binding protein homologous proteindependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells
-
Lin YD, Chen S, Yue P, Zou W, Benbrook DM, Liu S, Le TC, Berlin KD, Khuri FR, Sun SY. CAAT/ enhancer binding protein homologous proteindependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells. Cancer Res. 2008; 68(13):5335-44.
-
(2008)
Cancer Res
, vol.68
, Issue.13
, pp. 5335-5344
-
-
Lin, Y.D.1
Chen, S.2
Yue, P.3
Zou, W.4
Benbrook, D.M.5
Liu, S.6
Le, T.C.7
Berlin, K.D.8
Khuri, F.R.9
Sun, S.Y.10
-
29
-
-
39449093377
-
Acetyl-keto-betaboswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells
-
Lu M, Xia L, Hua H, Jing Y. Acetyl-keto-betaboswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells. Cancer Res. 2008; 68(4):1180-86.
-
(2008)
Cancer Res
, vol.68
, Issue.4
, pp. 1180-1186
-
-
Lu, M.1
Xia, L.2
Hua, H.3
Jing, Y.4
-
30
-
-
0141705424
-
Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis- inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo
-
Singh TR, Shankar S, Chen X, Asim M, Srivastava RK. Synergistic interactions of chemotherapeutic drugs and tumor necrosis factor-related apoptosis- inducing ligand/Apo-2 ligand on apoptosis and on regression of breast carcinoma in vivo. Cancer Res. 2003; 63(17):5390-400.
-
(2003)
Cancer Res
, vol.63
, Issue.17
, pp. 5390-5400
-
-
Singh, T.R.1
Shankar, S.2
Chen, X.3
Asim, M.4
Srivastava, R.K.5
-
32
-
-
58149330604
-
Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells
-
Wilson TR, McEwan M, McLaughlin K, Le Cloren nec C, Allen WL, Fennell DA, Johnston PG, Longley DB. Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells. Oncogene. 2009; 28 (1):63-72.
-
(2009)
Oncogene
, vol.28
, Issue.1
, pp. 63-72
-
-
Wilson, T.R.1
McEwan, M.2
McLaughlin, K.3
le Cloren, N.C.4
Allen, W.L.5
Fennell, D.A.6
Johnston, P.G.7
Longley, D.B.8
-
33
-
-
77956702972
-
Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation
-
Apr 16. [Epub ahead of print]
-
Maas C, Verbrugge I, de Vries E, Savich G, van de Kooij LW, Tait SW, Borst J. Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation. Cell Death Differ. 2010 Apr 16. [Epub ahead of print]
-
(2010)
Cell Death Differ
-
-
Maas, C.1
Verbrugge, I.2
de Vries, E.3
Savich, G.4
van de Kooij, L.W.5
Tait, S.W.6
Borst, J.7
-
34
-
-
77951923949
-
Ricci JE Mitochondrial control of caspase-dependent and independent cell death
-
Pradelli LA, Bénéteau M, Ricci JE Mitochondrial control of caspase-dependent and independent cell death. Cell Mol Life Sci. 2010; 67(10):1589-97.
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.10
, pp. 1589-1597
-
-
Pradelli, L.A.1
Bénéteau, M.2
-
35
-
-
70450205079
-
Apoptosis and human diseases: Mitochondrion damage and lethal role of released cytochrome c as proapoptotic protein
-
Caroppi P, Sinibaldi F, Fiorucci L, Santucci R. Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome c as proapoptotic protein. Curr Med Chem. 2009; 16(31):4058-65.
-
(2009)
Curr Med Chem
, vol.16
, Issue.31
, pp. 4058-4065
-
-
Caroppi, P.1
Sinibaldi, F.2
Fiorucci, L.3
Santucci, R.4
-
36
-
-
77956414973
-
Phase I doseescalation study of recombinant human Apo2L/ TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer
-
Herbst RS, Eckhardt SG, Kurzrock R, Ebbinghaus S, O'Dwyer PJ, Gordon MS, Novotny W, Goldwasser MA, Tohnya TM, Lum BL, Ashkenazi A, Jubb AM, Mendelson DS. Phase I doseescalation study of recombinant human Apo2L/ TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer. J Clin Oncol. 2010;28(17):2839-46.
-
(2010)
J Clin Oncol
, vol.28
, Issue.17
, pp. 2839-2846
-
-
Herbst, R.S.1
Eckhardt, S.G.2
Kurzrock, R.3
Ebbinghaus, S.4
O'Dwyer, P.J.5
Gordon, M.S.6
Novotny, W.7
Goldwasser, M.A.8
Tohnya, T.M.9
Lum, B.L.10
Ashkenazi, A.11
Jubb, A.M.12
Mendelson, D.S.13
|