Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis

International Journal of Cancer

Volumn 122, Issue 10, 2008, Pages 2210-2222

  Liu, Lei ^a   Xing, Da ^a   Chen, Wei R ^a,b   Chen, Tongsheng ^a   Pei, Yihui ^a   Gao, Xuejuan ^a  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF CENTRAL OKLAHOMA   (United States)

Author keywords

Apoptosis; Bid; Calpain; Caspase 8; Cisplatin

Indexed keywords

BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CALPAIN; CALPEPTIN; CASPASE 2; CASPASE 3; CASPASE 8; CISPLATIN; CYTOCHROME C; PD 150606; PROTEIN BID; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BID PROTEIN, HUMAN; CASPASE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ADENOCARCINOMA; CELL CULTURE; CLINICAL TRIAL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; LUNG TUMOR; METABOLISM; MULTICENTER STUDY; PATHOLOGY; WESTERN BLOTTING;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOTTING, WESTERN; CALPAIN; CASPASES; CISPLATIN; CYTOCHROMES C; HUMANS; LUNG NEOPLASMS; MITOCHONDRIA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 42149164851     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23378     Document Type: Article

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