Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

EMBO Journal

Volumn 22, Issue 17, 2003, Pages 4385-4399

  Arnoult, Damien ^a   Gaume, Brigitte ^a   Karbowski, Mariusz ^a   Sharpe, Juanita C ^a   Cecconi, Francesco ^b   Youle, Richard J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

AIF; Cytochrome c; Diablo; EndoG; HtrA2; Omi; Smac

Indexed keywords

APOPTOSIS INDUCING FACTOR; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CYTOCHROME C; ENDONUCLEASE G; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL DEATH; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MAMMAL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NEMATODE; OUTER MEMBRANE; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CAENORHABDITIS ELEGANS; CARRIER PROTEINS; CASPASES; CYTOCHROME C GROUP; DNA FRAGMENTATION; ENDODEOXYRIBONUCLEASES; ENZYME ACTIVATION; FLAVOPROTEINS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PERMEABILITY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; STAUROSPORINE;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; MAMMALIA; NEMATODA;

EID: 0042237031     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg423     Document Type: Article

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