Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells

Carcinogenesis

Volumn 30, Issue 2, 2009, Pages 197-204

  Jiang, Chen Chen ^a   Mao, Zhi Gang ^a   Avery Kiejda, Kelly A ^a   Wade, Margaret ^a   Hersey, Peter ^a   Zhang, Xu Dong ^a  

^a NEWCASTLE MATER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CALPASTATIN; CALPEPTIN; CASPASE 4; CASPASE 7; CISPLATIN; DOXORUBICIN; GLUCOSE REGULATED PROTEIN 78; MESSENGER RNA; SMALL INTERFERING RNA; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ISOLATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; RNA INTERFERENCE;

ANTINEOPLASTIC AGENTS; CALPAIN; CASPASE 7; CASPASE 9; CASPASES, INITIATOR; CELL LINE, TUMOR; CISPLATIN; DNA-BINDING PROTEINS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; HEAT-SHOCK PROTEINS; HUMANS; MELANOMA; MOLECULAR CHAPERONES; PROTEIN FOLDING; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 60149083508     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn220     Document Type: Article

References (45)

1. Soengas,M.S. et al. (2003) Apoptosis and melanoma chemoresistance. Oncogene, 22, 3138-3151.
2. Hersey,P. et al. (2006) Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model. Int. Rev. Cytol., 251, 131-158.
3. Harding,H.P. et al. (2002) Transcriptional and translational control in the mammalian unfolded protein response. Annu. Rev. Cell Dev. Biol., 18, 575-599.
4. Zhang,K. et al. (2004) Signaling the unfolded protein response from the endoplasmic reticulum. J. Biol. Chem., 279, 25935-25938.
5. Schroder,M. et al. (2005) The mammalian unfolded protein response. Annu. Rev. Biochem., 74, 739-789.
6. Ferri,K.F. et al. (2001) Organelle-specific initiation of cell death pathways. Nat. Cell Biol., 3, E255-E263.
7. Boyce,M. et al. (2006) Cellular response to endoplasmic reticulum stress: A matter of life or death. Cell Death Differ., 13, 363-373.
8. McCullough,K.D. et al. (2001) Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol. Cell. Biol., 21, 1249-1259.
9. Li,J. et al. (2006) Endoplasmic reticulum stress-induced apoptosis: Multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J. Biol. Chem., 281, 7260-7270.
10. Hitomi,J. et al. (2004) Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and abeta-induced cell death. J. Cell Biol., 165, 347-356.
11. Obeng,E.A. et al. (2005) Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis. J. Biol. Chem., 280, 29578-29587.
12. Saleh,M. et al. (2006) Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature, 440, 1064-1068.
13. Jiang,C.C. et al. (2007) Inhibition of MEK/ERK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis by enhancing caspase-4 activation. Cancer Res., 67, 9750-9761.
14. Lee,A.S. (2007) GRP78 induction in cancer: Therapeutic and prognostic implications. Cancer Res., 67, 3496-3499.
15. Ma,Y. et al. (2004) The role of the unfolded protein response in tumour development: Friend or foe? Nat. Rev. Cancer, 4, 966-977.
16. Rutkowski,D.T. et al. (2006) Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol., 4, e374.
17. Rutkowski,D.T. et al. (2007) That which does not kill me makes me stronger: Adapting to chronic ER stress. Trends Biochem. Sci., 32, 469-476.
18. Reddy,R.K. et al. (2003) Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J. Biol. Chem., 278, 20915-20924.
19. Pyrko,P. et al. (2007) The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res., 67, 9809-9816.
20. Mandic,A. et al. (2003) Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling. J. Biol. Chem. 278, 9100-9106.
21. Zhang,X.D. et al. (1999) Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res., 59, 2747-2753.
22. Nguyen,D.T. et al. (2001) Regulation of TRAIL induced apoptosis of fresh melanoma isolates. Clin. Cancer Res., 7, 966s-973s.
23. Jiang,C.C. et al. (2007) Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response. Cancer Res., 67, 5880-5888.
24. Zhang,X.D. et al. (2006) Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin. Clin. Cancer Res., 12, 1355-1364.
25. Chen,L.H. et al. (2007) Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response. Carcinogenesis, 28, 2328-2336.
26. Del Bello,B. et al. (2007) Cross-talk between calpain and caspase-3/-7 in cisplatin-induced apoptosis of melanoma cells: A major role of calpain inhibition in cell death protection and p53 status. Oncogene, 26, 2717-2726.
27. Hirota,M. et al. (2006) Quantitative measurement of spliced XBP1 mRNA as an indicator of endoplasmic reticulum stress. J. Toxicol. Sci., 31, 149-156.
28. Koong,A.C. et al. (2006) Targeting XBP-1 as a novel anti-cancer strategy. Cancer Biol. Ther., 5, 756-759.
29. Li,J. et al. (2006) Stress induction of GRP78/BiP and its role in cancer. Curr. Mol. Med., 6, 45-54.
30. Lee,A.S. (2005) The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress. Methods, 35, 373-381.
31. Finck,S.J. et al. (1983) LDH and melanoma. Cancer, 51, 840-843.
32. Hersey,P. et al. (2008) Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma. Pigment Cell Melanoma Res., 21, 358-367.
33. Denoyelle,C. et al. (2006) Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat. Cell Biol., 8, 1053-1063.
34. Fisher,D.E. (1994) Apoptosis in cancer therapy: Crossing the threshold. Cell, 78, 539-542.
35. Nawrocki,S.T. et al. (2005) Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res., 65, 11658-11666.
36. Hall,M.D. et al. (2008) The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy. Annu. Rev. Pharmacol. Toxicol., 48, 495-535.
37. Frank,N.Y. et al. (2005) ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res., 65 4320-4333.
38. Salvesen,G.S. et al. (2008) Caspase mechanisms. Adv. Exp. Med. Biol., 615, 13-23.
39. Nakagawa,T. et al. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature, 403, 98-103.
40. Yoneda,T. et al. (2001) Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J. Biol. Chem., 276, 13935-13940.
41. Mann,M.J. et al. (2006) UPR activation alters chemosensitivity of tumor cells. Cancer Biol. Ther., 5, 736-740.
42. Hu,P. et al. (2004) Critical role of endogenous Akt/IAPs and MEK1/ ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J. Biol. Chem., 279, 49420-49429.
43. Stahl,J.M. et al. (2004) Deregulated Akt3 activity promotes development of malignant melanoma. Cancer Res., 64, 7002-7010.
44. Ermakova,S.P. et al. (2006) (-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78. Cancer Res., 66, 9260-9269.
45. Park,H.R. et al. (2004) Effect on tumor cells of blocking survival response to glucose deprivation. J. Natl Cancer Inst., 96, 1300-1310.