Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2,-3,-6,-7,-8, and -10 in a caspase-9-dependent manner

Journal of Cell Biology

Volumn 144, Issue 2, 1999, Pages 281-292

  Slee, Elizabeth A ^a   Harte, Mary T ^a   Kluck, Ruth M ^b   Wolf, Beni B ^b   Casiano, Carlos A ^c   Newmeyer, Donald D ^b   Wang, Hong Gang ^d   Reed, John C ^d   Nicholson, Donald W ^e   Alnemri, Emad S ^f   Green, Douglas R ^b   Martin, Seamus J ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d BURNHAM INSTITUTE   (United States)

^e MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apaf 1; Apoptosis; Caspases; Cell free; Cytochrome C

Indexed keywords

ADAPTOR PROTEIN; CASPASE; CASPASE 3; CYTOCHROME C; INTERLEUKIN 1BETA CONVERTING ENZYME;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEPLETION; ENZYME ACTIVATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CASPASE 10; CASPASE 2; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; CASPASES; CELL EXTRACTS; CYTOCHROME C GROUP; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; RABBITS;

EID: 0033601746     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.144.2.281     Document Type: Article

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