TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

Journal of Clinical Investigation

Volumn 110, Issue 6, 2002, Pages 835-842

  Ramesh, Ganesan ^a   Brian Reeves, W ^a,b,c  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; ILOMASTAT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PENTOXIFYLLINE; RANTES; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; KIDNEY INJURY; LEUKOCYTE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY;

ANIMALS; ANTINEOPLASTIC AGENTS; CHEMOKINES; CISPLATIN; CYTOKINES; DIPEPTIDES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; KIDNEY; KIDNEY FAILURE, ACUTE; MALE; MICE; MICE, KNOCKOUT; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036738517     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200215606     Document Type: Article

References (49)

1. Clinical development of platinum complexes in cancer therapy: An historical perspective and an update
2. Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity
3. Critical subcellular targets of cisplatin and related platinum analogs in rat renal proximal tubule cells
4. Adverse effects of anti-tumor drug, cisplatin, on rat kidney mitochrondria: Disturbances in glutathione peroxidase activity
5. The role of oxygen free radicals in cisplatin-induced acute renal failure in rats
6. Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells
7. Mechanisms of death induced by cisplatin in proximal tubular eipthelial cells: Apoptosis vs. necrosis
8. 1
9. Cell biology and molecular mechanisms of injury in ischemic acute renal failure
10. + T cell as a major pathogenic factor in ischemic acute renal failure
11. Protection from toxicant-mediated renal injury in the rat with anti-CD54 antibody
12. Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury
13. In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity
14. Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis
15. Manganese superoxide dismutase attenuates cisplatin-induced renal injury: Importance of superoxide
16. Nuclear factor-kB: A pivotal transcription factor in chronic inflammatory diseases
17. Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
18. Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure
19. Anti-body to intercellular adhesion molecule-1 protects the kidney against ischemic injury
20. Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice
21. Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme
22. TNFα
23. Pentoxyfylline efficacy in the treatment of intermittent claudication
24. Differential regulation of TNFα, IL-1β, IL-6, IL-8, TNFβ, and IL-10 by pentoxifylline
25. Tumor necrosis factor-alpha converting enzyme
26. A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
27. Assessment of cisplatin-induced nephrotoxicity by microarray technology
28. GP130-signaling cytokines and of the chemokine MIP-2 in murine renal inschemia-reperfusion injury
29. The cytokine-adhension molecule cascade in ischemia/reperfusion injury of the rat kidney
30. Chemokine and chemokine receptor expression in a novel human mesangial cell line
31. Chemotactic factors and renal inflammation
32. Effect of neutrophil depletion on ischemic renal injury in the rat
33. IL-10
34. Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion
35. Involvement of endogenous interleukin-10 and tumor necrosis factor-α in renal ischemia-reperfusion injury
36. Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase
37. Induction of heme oxygenase in toxic renal injury: A protective role in cisplatin nephrotoxicity in the rat
38. 2) injury
39. α-melanocyte-simulating hormone and interleukin-10 do not protect the kidney against mercuric chloride-induced injury
40. 2-induced acute renal failure
41. Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure
42. 1 renal epirhelial cells
43. The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but nor necrosis of renal epithelial cells
44. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
45. Overexpression of catalase in the mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to tumor necrosis factor-alpha-induced apoptosis
46. Role of free radicals and catalytic metal ions in human disease: An overview
47. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1
48. Modulation of tumor necrosis factor by reactive oxygen metabolites
49. IL-1 and TNF independent pathways mediate ICAM-1/VCAM-1 up-regulation in ischemia reperfusion injury