메뉴 건너뛰기




Volumn 1, Issue 1, 2010, Pages

C-Abl phosphorylation of Δnp63α is critical for cell viability

Author keywords

c Abl; cisplatin; p63; Yes associated protein

Indexed keywords

ABELSON KINASE; CISPLATIN; MUTANT PROTEIN; PROTEIN P53; PROTEIN YAP; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ISOPROTEIN; NUCLEAR PROTEIN; TP63 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; YY1AP1 PROTEIN, HUMAN;

EID: 77954784171     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2009.15     Document Type: Review
Times cited : (47)

References (40)
  • 3
    • 0032161624 scopus 로고    scopus 로고
    • P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominantnegative activities. Mol Cell 1998; 2: 305-316. (Pubitemid 128379271)
    • (1998) Molecular Cell , vol.2 , Issue.3 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9
  • 4
    • 0033594491 scopus 로고    scopus 로고
    • P63 is a p53 homologue required for limb and epidermal morphogenesis
    • DOI 10.1038/19531
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999; 398: 708-713. (Pubitemid 29197649)
    • (1999) Nature , vol.398 , Issue.6729 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.-J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 9
    • 17444390129 scopus 로고    scopus 로고
    • Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
    • DOI 10.1016/j.ccr.2005.02.019
    • Flores ER, Sengupta S, Miller JB, Newman JJ, Bronson R, Crowley D et al. Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell 2005; 7: 363-373. (Pubitemid 40544653)
    • (2005) Cancer Cell , vol.7 , Issue.4 , pp. 363-373
    • Flores, E.R.1    Sengupta, S.2    Miller, J.B.3    Newman, J.J.4    Bronson, R.5    Crowley, D.6    Yang, A.7    McKeon, F.8    Jacks, T.9
  • 10
    • 0037041392 scopus 로고    scopus 로고
    • P63 and p73 are required for p53-dependent apoptosis in response to DNA damage
    • DOI 10.1038/416560a
    • Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F et al. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 2002; 416: 560-564. (Pubitemid 34288861)
    • (2002) Nature , vol.416 , Issue.6880 , pp. 560-564
    • Flores, E.R.1    Tsai, K.Y.2    Crowley, D.3    Sengupta, S.4    Yang, A.5    McKeon, F.6    Jacks, T.7
  • 11
    • 33646798450 scopus 로고    scopus 로고
    • P53/p63/p73 isoforms: An orchestra of isoforms to harmonise cell differentiation and response to stress
    • Murray-Zmijewski F, Lane DP, Bourdon JC. p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ 2006; 13: 962-972.
    • (2006) Cell Death Differ , vol.13 , pp. 962-972
    • Murray-Zmijewski, F.1    Lane, D.P.2    Bourdon, J.C.3
  • 12
    • 53549134949 scopus 로고    scopus 로고
    • TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
    • Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC et al. TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev 2008; 22: 2677-2691.
    • (2008) Genes Dev , vol.22 , pp. 2677-2691
    • Tomasini, R.1    Tsuchihara, K.2    Wilhelm, M.3    Fujitani, M.4    Rufini, A.5    Cheung, C.C.6
  • 13
    • 0033600240 scopus 로고    scopus 로고
    • Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
    • Agami R, Blandino G, Oren M, Shaul Y. Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature 1999; 399: 809-813.
    • (1999) Nature , vol.399 , pp. 809-813
    • Agami, R.1    Blandino, G.2    Oren, M.3    Shaul, Y.4
  • 14
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • DOI 10.1038/21690
    • Gong JG, Costanzo A, Yang HQ, Melino G, Kaelin Jr WG, Levrero M et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 1999; 399: 806-809. (Pubitemid 29293179)
    • (1999) Nature , vol.399 , Issue.6738 , pp. 806-809
    • Gong, J.1    Costanzo, A.2    Yang, H.-Q.3    Mellno, G.4    Kaelin Jr., W.G.5    Levrero, M.6    Wang, J.Y.J.7
  • 15
    • 34548014527 scopus 로고    scopus 로고
    • How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?
    • DOI 10.1038/sj.cdd.4402196, PII 4402196
    • Olsson A, Manzl C, Strasser A, Villunger A. How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? Cell Death Differ 2007; 14: 1561-1575. (Pubitemid 47278842)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.9 , pp. 1561-1575
    • Olsson, A.1    Manzl, C.2    Strasser, A.3    Villunger, A.4
  • 17
    • 0033536230 scopus 로고    scopus 로고
    • Mdm2 binds p73α without targeting degradation
    • DOI 10.1038/sj.onc.1202781
    • Balint E, Bates S, Vousden KH. Mdm2 binds p73 alpha without targeting degradation. Oncogene 1999; 18: 3923-3929. (Pubitemid 29361329)
    • (1999) Oncogene , vol.18 , Issue.27 , pp. 3923-3929
    • Balint, E.1    Bates, S.2    Vousden, K.H.3
  • 20
    • 0035805487 scopus 로고    scopus 로고
    • Physical interaction with Yes-associated protein enhances p73 transcriptional activity
    • Strano S, Munarriz E, Rossi M, Castagnoli L, Shaul Y, Sacchi A et al. Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem 2001; 276: 15164-15173.
    • (2001) J Biol Chem , vol.276 , pp. 15164-15173
    • Strano, S.1    Munarriz, E.2    Rossi, M.3    Castagnoli, L.4    Shaul, Y.5    Sacchi, A.6
  • 21
    • 0037249343 scopus 로고    scopus 로고
    • Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
    • DOI 10.1016/S1097-2765(02)00776-1
    • Basu S, Totty NF, Irwin MS, Sudol M, Downward J. Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell 2003; 11: 11-23. (Pubitemid 36126587)
    • (2003) Molecular Cell , vol.11 , Issue.1 , pp. 11-23
    • Basu, S.1    Totty, N.F.2    Irwin, M.S.3    Sudol, M.4    Downward, J.5
  • 22
    • 57749084642 scopus 로고    scopus 로고
    • PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop
    • Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G et al. PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell 2008; 32: 803-814.
    • (2008) Mol Cell , vol.32 , pp. 803-814
    • Lapi, E.1    Di Agostino, S.2    Donzelli, S.3    Gal, H.4    Domany, E.5    Rechavi, G.6
  • 23
    • 38949123978 scopus 로고    scopus 로고
    • Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage
    • DOI 10.1016/j.molcel.2007.12.022, PII S1097276508000646
    • Levy D, Adamovich Y, Reuven N, Shaul Y. Yap1 phosphorylation by c-Abl is a critical step in selective activation of pro-apoptotic genes in response to DNA damage. Mol Cell 2008; 29: 350-361. (Pubitemid 351215937)
    • (2008) Molecular Cell , vol.29 , Issue.3 , pp. 350-361
    • Levy, D.1    Adamovich, Y.2    Reuven, N.3    Shaul, Y.4
  • 25
    • 37349005990 scopus 로고    scopus 로고
    • Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis [3]
    • DOI 10.1038/sj.cdd.4402226, PII 4402226, Special issue on Tumor stress, cell death and the ensuing immune response
    • Danovi SA, Rossi M, Gudmundsdottir K, Yuan M, Melino G, Basu S. Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis. Cell Death Differ 2008; 15: 217-219. (Pubitemid 350286191)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.1 , pp. 217-219
    • Danovi, S.A.1    Rossi, M.2    Gudmundsdottir, K.3    Yuan, M.4    Melino, G.5    Basu, S.6
  • 26
    • 33947382284 scopus 로고    scopus 로고
    • The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73
    • DOI 10.1038/sj.cdd.4402063, PII 4402063
    • Levy D, Adamovich Y, Reuven N, Shaul Y. The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death Differ 2007; 14: 743-751. (Pubitemid 46444512)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.4 , pp. 743-751
    • Levy, D.1    Adamovich, Y.2    Reuven, N.3    Shaul, Y.4
  • 27
    • 19644387170 scopus 로고    scopus 로고
    • Role of c-Abl in the DNA damage stress response
    • DOI 10.1038/sj.cr.7290261
    • Shaul Y, Ben-Yehoyada M. Role of c-Abl in the DNA damage stress response. Cell Res 2005; 15: 33-35. (Pubitemid 41653962)
    • (2005) Cell Research , vol.15 , Issue.1 , pp. 33-35
    • Shaul, Y.1    Ben-Yehoyada, M.2
  • 28
    • 0037169351 scopus 로고    scopus 로고
    • Autoinhibition of c-Abl
    • DOI 10.1016/S0092-8674(02)00623-2
    • Pluk H, Dorey K, Superti-Furga G. Autoinhibition of c-Abl. Cell 2002; 108: 247-259. (Pubitemid 34161144)
    • (2002) Cell , vol.108 , Issue.2 , pp. 247-259
    • Pluk, H.1    Dorey, K.2    Superti-Furga, G.3
  • 31
    • 30344450404 scopus 로고    scopus 로고
    • P63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
    • DOI 10.1016/j.ccr.2005.12.013, PII S1535610805003946
    • Rocco JW, Leong CO, Kuperwasser N, DeYoung MP, Ellisen LW. p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis. Cancer Cell 2006; 9: 45-56. (Pubitemid 43069510)
    • (2006) Cancer Cell , vol.9 , Issue.1 , pp. 45-56
    • Rocco, J.W.1    Leong, C.-O.2    Kuperwasser, N.3    DeYoung, M.P.4    Ellisen, L.W.5
  • 32
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996; 2: 561-566.
    • (1996) Nat Med , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3    Ohno, S.4    Segal, G.M.5    Fanning, S.6
  • 34
    • 33750378033 scopus 로고    scopus 로고
    • Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma
    • DOI 10.1158/0008-5472.CAN-06-1619
    • DeYoung MP, Johannessen CM, Leong CO, Faquin W, Rocco JW, Ellisen LW. Tumorspecific p73 up-regulation mediates p63 dependence in squamous cell carcinoma. Cancer Res 2006; 66: 9362-9368. (Pubitemid 44623630)
    • (2006) Cancer Research , vol.66 , Issue.19 , pp. 9362-9368
    • DeYoung, M.P.1    Johannessen, C.M.2    Leong, C.-O.3    Faquin, W.4    Rocco, J.W.5    Ellisen, L.W.6
  • 35
    • 34248166978 scopus 로고    scopus 로고
    • The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers
    • DOI 10.1172/JCI30866
    • Leong CO, Vidnovic N, DeYoung MP, Sgroi D, Ellisen LW. The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers. J Clin Invest 2007; 117: 1370-1380. (Pubitemid 46718425)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1370-1380
    • Leong, C.-O.1    Vidnovic, N.2    DeYoung, M.P.3    Sgroi, D.4    Ellisen, L.W.5
  • 36
    • 70350506325 scopus 로고    scopus 로고
    • Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death
    • Gonfloni S, Di Tella L, Caldarola S, Cannata SM, Klinger FG, Di Bartolomeo C et al. Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med 2009; 15: 1179-1185.
    • (2009) Nat Med , vol.15 , pp. 1179-1185
    • Gonfloni, S.1    Di Tella, L.2    Caldarola, S.3    Cannata, S.M.4    Klinger, F.G.5    Di Bartolomeo, C.6
  • 37
    • 47949106116 scopus 로고    scopus 로고
    • Activated c-Abl tyrosine kinase in malignant solid tumors
    • Lin J, Arlinghaus R. Activated c-Abl tyrosine kinase in malignant solid tumors. Oncogene 2008; 27: 4385-4391.
    • (2008) Oncogene , vol.27 , pp. 4385-4391
    • Lin, J.1    Arlinghaus, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.