Cisplatin-induced apoptotic cell death in mouse hybrid neurons is blocked by antioxidants through suppression of cisplatin-mediated accumulation of p53 but not of Fas/Fas ligand

Journal of Neurochemistry

Volumn 75, Issue 3, 2000, Pages 946-953

  Park, Sun Ah ^a,b   Choi, Kyeong Sook ^a,b   Bang, Jung Hee ^a,b   Huh, Kyoon ^a,b   Kim, Seung U ^a,b,c  

^a Ajou University School of Medicine   (South Korea)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antioxidants; Apoptosis; Cisplatin; Fas; Fas ligand; Hybrid neuron; N Acetylcysteine; p21; p53; Trolox

Indexed keywords

ANTIOXIDANT; CISPLATIN; FAS LIGAND; PROTEIN; PROTEIN P53; TROLOX C;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; HYBRID CELL; IMMUNOBLOTTING; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; ANTIGENS, CD95; ANTIOXIDANTS; APOPTOSIS; CELL NUCLEUS; CELL SURVIVAL; CHROMANS; CISPLATIN; DNA FRAGMENTATION; FAS LIGAND PROTEIN; GANGLIA, SPINAL; HYBRID CELLS; KINETICS; MEMBRANE GLYCOPROTEINS; MICE; NEUROBLASTOMA; NEURONS, AFFERENT; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033840566     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0750946.x     Document Type: Article

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