Transient Expression of Wild-type or Mitochondrially Targeted Bcl-2 Induces Apoptosis, whereas Transient Expression of Endoplasmic Reticulum-targeted Bcl-2 Is Protective against Bax-induced Cell Death

Journal of Biological Chemistry

Volumn 276, Issue 47, 2001, Pages 44117-44128

  Wang, Nancy S ^c   Unkila, Mikko T ^a   Reineks, Edmunds Z ^c   Distelhorst, Clark W ^b  

^a Hormos Medical Ltd   (Finland)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; ENZYME INHIBITION; PROTEINS;

CELL DEATH;

BIOCHEMISTRY;

CASPASE 3; MEMBRANE PROTEIN; PROTEIN BAX; PROTEIN BCL 2; BAX PROTEIN, HUMAN; ONCOPROTEIN; PRIMER DNA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL NUCLEUS MEMBRANE; CELL PROTECTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; CELL LINE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

APOPTOSIS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; DNA PRIMERS; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0035941360     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101958200     Document Type: Article

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