Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

Journal of Clinical Investigation

Volumn 106, Issue 9, 2000, Pages 1127-1137

  Guicciardi, M Eugenia ^a   Deussing, Jan ^b   Miyoshi, Hideyuki ^a   Bronk, Steven F ^a   Svingen, Phyllis A ^a   Peters, Christoph ^b   Kaufmann, Scott H ^a   Gores, Gregory J ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CATHEPSIN B; CYTOCHROME C; DACTINOMYCIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME RELEASE; GENE DELETION; LIVER CELL; LIVER CYTOSOL; LIVER INJURY; LYSOSOME; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0033756474     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI9914     Document Type: Article

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