Ca2+-Induced Apoptosis Through Calcineurin Dephosphorylation of BAD

Science

Volumn 284, Issue 5412, 1999, Pages 339-343

  Wang, Hong Gang ^a,b   Pathan, Nuzhat ^a   Ethell, Iryna M ^a   Krajewski, Stanislaw ^a   Yamaguchi, Yu ^a   Shibasaki, Futoshi ^c   McKeon, Frank ^c   Bobo, Tanya ^d   Franke, Thomas F ^d   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAD PROTEIN, HUMAN; BAD PROTEIN, RAT; BCL2L1 PROTEIN, HUMAN; BCL2L1 PROTEIN, RAT; CALCINEURIN; CALCIUM; CARRIER PROTEIN; ENZYME INHIBITOR; GLUTAMIC ACID; HYBRID PROTEIN; PROTEIN; PROTEIN 14 3 3; PROTEIN BAD; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN SERINE THREONINE KINASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL LINE; CHEMISTRY; CYTOLOGY; DIMERIZATION; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; HIPPOCAMPUS; HUMAN; METABOLISM; MITOCHONDRION; NERVE CELL; PHOSPHORYLATION; RAT;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; CALCINEURIN; CALCIUM; CARRIER PROTEINS; CELL LINE; CELLS, CULTURED; DIMERIZATION; ENZYME INHIBITORS; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; MITOCHONDRIA; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TYROSINE 3-MONOOXYGENASE;

EID: 0033537768     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.284.5412.339     Document Type: Article

References (3)

1. A. Rao, C. Luo, P. Hogan, Annu. Rev. Immunol. 15, 707 (1997).
2. F. Shibasaki, F. McKeon, J. Cell Biol. 131, 735 (1995);
3. F. Shibasaki, E. Kondo, T. Akagi, F. McKeon, Nature 386, 728 (1997).