-
1
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO. The biochemistry of apoptosis. Nature 2000; 407:770-6.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
2
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997; 89:175-84. (Pubitemid 27199890)
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
3
-
-
0035976991
-
CAD/DFF40 Nuclease Is Dispensable for High Molecular Weight DNA Cleavage and Stage I Chromatin Condensation in Apoptosis
-
DOI 10.1074/jbc.M108844200
-
Samejima K, Tone S, Earnshaw WC. CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis. J Biol Chem 2001; 276:45427-32. (Pubitemid 37391341)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.48
, pp. 45427-45432
-
-
Samejima, K.1
Tone, S.2
Earnshaw, W.C.3
-
4
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996; 184:1331-41.
-
(1996)
J Exp Med
, vol.184
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Hirsch, T.4
Marchetti, P.5
Macho, A.6
-
5
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397:441-6.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
-
6
-
-
36849028692
-
AIF-mediated programmed necrosis: A highly regulated way to die
-
Boujrad H, Gubkina O, Robert N, Krantic S, Susin SA. AIF-mediated programmed necrosis: a highly regulated way to die. Cell Cycle 2007; 6:2612-9.
-
(2007)
Cell Cycle
, vol.6
, pp. 2612-2619
-
-
Boujrad, H.1
Gubkina, O.2
Robert, N.3
Krantic, S.4
Susin, S.A.5
-
7
-
-
33847134493
-
Apoptosis-inducing factor: A matter of neuron life and death
-
Krantic S, Mechawar N, Reix S, Quirion R. Apoptosis-inducing factor: a matter of neuron life and death. Prog Neurobiol 2007; 81:179-96.
-
(2007)
Prog Neurobiol
, vol.81
, pp. 179-196
-
-
Krantic, S.1
Mechawar, N.2
Reix, S.3
Quirion, R.4
-
8
-
-
2442621492
-
Role of AIF in caspase-dependent and caspase-independent cell death
-
Cregan SP, Dawson VL, Slack RS. Role of AIF in caspase-dependent and caspase-independent cell death. Oncogene 2004; 23:2785-96.
-
(2004)
Oncogene
, vol.23
, pp. 2785-2796
-
-
Cregan, S.P.1
Dawson, V.L.2
Slack, R.S.3
-
9
-
-
0036323443
-
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
-
Cregan SP, Fortin A, MacLaurin JG, Callaghan SM, Cecconi F, Yu SW, et al. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J Cell Biol 2002; 158:507-17.
-
(2002)
J Cell Biol
, vol.158
, pp. 507-517
-
-
Cregan, S.P.1
Fortin, A.2
MacLaurin, J.G.3
Callaghan, S.M.4
Cecconi, F.5
Yu, S.W.6
-
10
-
-
17844394478
-
Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space
-
Otera H, Ohsakaya S, Nagaura Z, Ishihara N, Mihara K. Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space. EMBO J 2005; 24:1375-86.
-
(2005)
EMBO J
, vol.24
, pp. 1375-1386
-
-
Otera, H.1
Ohsakaya, S.2
Nagaura, Z.3
Ishihara, N.4
Mihara, K.5
-
11
-
-
27344458981
-
Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release
-
Yuste VJ, Moubarak RS, Delettre C, Bras M, Sancho P, Robert N, et al. Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release. Cell Death Differ 2005; 12:1445-8.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1445-1448
-
-
Yuste, V.J.1
Moubarak, R.S.2
Delettre, C.3
Bras, M.4
Sancho, P.5
Robert, N.6
-
12
-
-
14844328621
-
Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria
-
Polster BM, Basanez G, Etxebarria A, Hardwick JM, Nicholls DG. Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem 2005; 280:6447-54.
-
(2005)
J Biol Chem
, vol.280
, pp. 6447-6454
-
-
Polster, B.M.1
Basanez, G.2
Etxebarria, A.3
Hardwick, J.M.4
Nicholls, D.G.5
-
13
-
-
38549123294
-
Therapeutic potential of AIF-mediated caspase-independent programmed cell death
-
Lorenzo HK, Susin SA. Therapeutic potential of AIF-mediated caspase-independent programmed cell death. Drug Resist Updat 2007; 10:235-55.
-
(2007)
Drug Resist Updat
, vol.10
, pp. 235-255
-
-
Lorenzo, H.K.1
Susin, S.A.2
-
14
-
-
0034698733
-
Two distinct pathways leading to nuclear apoptosis
-
Susin SA, Daugas E, Ravagnan L, Samejima K, Zamzami N, Loeffler M, et al. Two distinct pathways leading to nuclear apoptosis. J Exp Med 2000; 192:571-80.
-
(2000)
J Exp Med
, vol.192
, pp. 571-580
-
-
Susin, S.A.1
Daugas, E.2
Ravagnan, L.3
Samejima, K.4
Zamzami, N.5
Loeffler, M.6
-
15
-
-
0036263870
-
The crystal structure of the mouse apoptosis-inducing factor AIF
-
Mate MJ, Ortiz-Lombardia M, Boitel B, Haouz A, Tello D, Susin SA, et al. The crystal structure of the mouse apoptosis-inducing factor AIF. Nat Struct Biol 2002; 9:442-6.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 442-446
-
-
Mate, M.J.1
Ortiz-Lombardia, M.2
Boitel, B.3
Haouz, A.4
Tello, D.5
Susin, S.A.6
-
16
-
-
18544371050
-
DNA binding is required for the apoptogenic action of apoptosis inducing factor
-
Ye H, Cande C, Stephanou NC, Jiang S, Gurbuxani S, Larochette N, et al. DNA binding is required for the apoptogenic action of apoptosis inducing factor. Nat Struct Biol 2002; 9:680-4.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 680-684
-
-
Ye, H.1
Cande, C.2
Stephanou, N.C.3
Jiang, S.4
Gurbuxani, S.5
Larochette, N.6
-
17
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135:1311-23.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
-
18
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNFalpha
-
He S, Wang L, Miao L, Wang T, Du F, Zhao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNFalpha. Cell 2009; 137:1100-11.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
-
19
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137:1112-23.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
-
20
-
-
67649526000
-
Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos
-
Wang Y, Dawson VL, Dawson TM. Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos. Exp Neurol 2009; 218:193-202.
-
(2009)
Exp Neurol
, vol.218
, pp. 193-202
-
-
Wang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
21
-
-
34347344991
-
Sequential Activation of Poly(ADP-Ribose) Polymerase 1, Calpains and Bax Is Essential in Apoptosis-Inducing Factor-Mediated Programmed Necrosis
-
Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, et al. Sequential Activation of Poly(ADP-Ribose) Polymerase 1, Calpains and Bax Is Essential in Apoptosis-Inducing Factor-Mediated Programmed Necrosis. Mol Cell Biol 2007; 27:4844-62.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4844-4862
-
-
Moubarak, R.S.1
Yuste, V.J.2
Artus, C.3
Bouharrour, A.4
Greer, P.A.5
Menissier-de Murcia, J.6
-
22
-
-
77951975356
-
AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX
-
Artus C, Boujrad H, Bouharrour A, Brunelle MN, Hoos S, Yuste VJ, et al. AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX. EMBO J 2010; 29:1585-99.
-
(2010)
EMBO J
, vol.29
, pp. 1585-1599
-
-
Artus, C.1
Boujrad, H.2
Bouharrour, A.3
Brunelle, M.N.4
Hoos, S.5
Yuste, V.J.6
-
23
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002; 297:259-63.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
-
24
-
-
2442624618
-
Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
-
Alano CC, Ying W, Swanson RA. Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J Biol Chem 2004; 279:18895-902.
-
(2004)
J Biol Chem
, vol.279
, pp. 18895-18902
-
-
Alano, C.C.1
Ying, W.2
Swanson, R.A.3
-
25
-
-
10844264632
-
Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: Reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria
-
Kang YH, Yi MJ, Kim MJ, Park MT, Bae S, Kang CM, et al. Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: Reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res 2004; 64:8960-7.
-
(2004)
Cancer Res
, vol.64
, pp. 8960-8967
-
-
Kang, Y.H.1
Yi, M.J.2
Kim, M.J.3
Park, M.T.4
Bae, S.5
Kang, C.M.6
-
26
-
-
33646827842
-
Poly(ADP-ribose) Polymerase-1 Signaling to Mitochondria in Necrotic Cell Death Requires RIP1/TRAF2-mediated JNK1 Activation
-
Xu Y, Huang S, Liu ZG, Han J. Poly(ADP-ribose) Polymerase-1 Signaling to Mitochondria in Necrotic Cell Death Requires RIP1/TRAF2-mediated JNK1 Activation. J Biol Chem 2006; 281:8788-95.
-
(2006)
J Biol Chem
, vol.281
, pp. 8788-8795
-
-
Xu, Y.1
Huang, S.2
Liu, Z.G.3
Han, J.4
-
27
-
-
33845317242
-
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
-
Yu SW, Andrabi SA, Wang H, Kim NS, Poirier GG, Dawson TM, et al. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc Natl Acad Sci USA 2006; 103:18314-9.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18314-18319
-
-
Yu, S.W.1
Andrabi, S.A.2
Wang, H.3
Kim, N.S.4
Poirier, G.G.5
Dawson, T.M.6
-
28
-
-
1342326780
-
MNNG induces dramatic DNA damage and nonapoptotic changes in cervical carcinoma HeLa cells
-
Wsierska-Gadek J, Gueorguieva M, Wojciechowski J. MNNG induces dramatic DNA damage and nonapoptotic changes in cervical carcinoma HeLa cells. Ann N Y Acad Sci 2003; 1010:278-82.
-
(2003)
Ann N Y Acad Sci
, vol.1010
, pp. 278-282
-
-
Wsierska-Gadek, J.1
Gueorguieva, M.2
Wojciechowski, J.3
-
30
-
-
26244461881
-
Targeting poly(ADP-ribosyl)ation: A promising approach in cancer therapy
-
Haince JF, Rouleau M, Hendzel MJ, Masson JY, Poirier GG. Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy. Trends Mol Med 2005; 11:456-63.
-
(2005)
Trends Mol Med
, vol.11
, pp. 456-463
-
-
Haince, J.F.1
Rouleau, M.2
Hendzel, M.J.3
Masson, J.Y.4
Poirier, G.G.5
-
31
-
-
0034733928
-
Poly(ADP-ribose) polymerase-1: What have we learned from the deficient mouse model?
-
Shall S, de Murcia G. Poly(ADP-ribose) polymerase-1: What have we learned from the deficient mouse model? Mutat Res 2000; 460:1-15.
-
(2000)
Mutat Res
, vol.460
, pp. 1-15
-
-
Shall, S.1
De Murcia, G.2
-
32
-
-
0037469097
-
Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax
-
Toyota H, Yanase N, Yoshimoto T, Moriyama M, Sudo T, Mizuguchi J. Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax. Cancer Lett 2003; 189:221-30.
-
(2003)
Cancer Lett
, vol.189
, pp. 221-230
-
-
Toyota, H.1
Yanase, N.2
Yoshimoto, T.3
Moriyama, M.4
Sudo, T.5
Mizuguchi, J.6
-
33
-
-
1642565065
-
The p18 truncated form of Bax behaves like a Bcl-2 homology domain 3-only protein
-
Cartron PF, Oliver L, Juin P, Meflah K, Vallette FM. The p18 truncated form of Bax behaves like a Bcl-2 homology domain 3-only protein. J Biol Chem 2004; 279:11503-12.
-
(2004)
J Biol Chem
, vol.279
, pp. 11503-11512
-
-
Cartron, P.F.1
Oliver, L.2
Juin, P.3
Meflah, K.4
Vallette, F.M.5
-
34
-
-
0141481980
-
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis and a cathepsin-like protease may rapidly degrade p18 Bax
-
Cao X, Deng X, May WS. Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis and a cathepsin-like protease may rapidly degrade p18 Bax. Blood 2003; 102:2605-14.
-
(2003)
Blood
, vol.102
, pp. 2605-2614
-
-
Cao, X.1
Deng, X.2
May, W.S.3
-
35
-
-
0029854806
-
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: Contributory roles of both protease families in neuronal apoptosis
-
Nath R, Raser KJ, Stafford D, Hajimohammadreza I, Posner A, Allen H, et al. Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: Contributory roles of both protease families in neuronal apoptosis. Biochem J 1996; 319:683-90.
-
(1996)
Biochem J
, vol.319
, pp. 683-690
-
-
Nath, R.1
Raser, K.J.2
Stafford, D.3
Hajimohammadreza, I.4
Posner, A.5
Allen, H.6
-
36
-
-
0038337815
-
The calpain system
-
Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system. Physiol Rev 2003; 83:731-801.
-
(2003)
Physiol Rev
, vol.83
, pp. 731-801
-
-
Goll, D.E.1
Thompson, V.F.2
Li, H.3
Wei, W.4
Cong, J.5
-
37
-
-
33751239138
-
Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors
-
Sanges D, Comitato A, Tammaro R, Marigo V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci USA 2006; 103:17366-71.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17366-17371
-
-
Sanges, D.1
Comitato, A.2
Tammaro, R.3
Marigo, V.4
-
38
-
-
33748939906
-
CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells
-
DOI 10.1038/sj.onc.1209581, PII 1209581
-
Artus C, Maquarre E, Moubarak RS, Delettre C, Jasmin C, Susin SA, et al. CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells. Oncogene 2006; 25:5741-51. (Pubitemid 44435251)
-
(2006)
Oncogene
, vol.25
, Issue.42
, pp. 5741-5751
-
-
Artus, C.1
Maquarre, E.2
Moubarak, R.S.3
Delettre, C.4
Jasmin, C.5
Susin, S.A.6
Robert-Lezenes, J.7
-
39
-
-
34548431366
-
Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury
-
DOI 10.1523/JNEUROSCI.2826-07.2007
-
Cao G, Xing J, Xiao X, Liou AK, Gao Y, Yin XM, et al. Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury. J Neurosci 2007; 27:9278-93. (Pubitemid 47358221)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.35
, pp. 9278-9293
-
-
Cao, G.1
Xing, J.2
Xiao, X.3
Liou, A.K.F.4
Gao, Y.5
Yin, X.-M.6
Clark, R.S.B.7
Graham, S.H.8
Chen, J.9
-
40
-
-
0036850312
-
Bid, Bax and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana T, Mackey MR, Perkins G, Ellisman MH, Latterich M, Schneiter R, et al. Bid, Bax and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 2002; 111:331-42.
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
-
41
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
DOI 10.1016/j.molcel.2005.02.003
-
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, et al. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 2005; 17:525-35. (Pubitemid 40269117)
-
(2005)
Molecular Cell
, vol.17
, Issue.4
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
Newmeyer, D.D.7
-
42
-
-
33748961826
-
Mitochondria as the target of the pro-apoptotic protein Bax
-
Er E, Oliver L, Cartron PF, Juin P, Manon S, Vallette FM. Mitochondria as the target of the pro-apoptotic protein Bax. Biochim Biophys Acta 2006.
-
(2006)
Biochim Biophys Acta
-
-
Er, E.1
Oliver, L.2
Cartron, P.F.3
Juin, P.4
Manon, S.5
Vallette, F.M.6
-
43
-
-
14644441669
-
Newcomers in the process of mitochondrial permeabilization
-
Lucken-Ardjomande S, Martinou JC. Newcomers in the process of mitochondrial permeabilization. J Cell Sci 2005; 118:473-83.
-
(2005)
J Cell Sci
, vol.118
, pp. 473-483
-
-
Lucken-Ardjomande, S.1
Martinou, J.C.2
-
44
-
-
0034523818
-
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
-
DOI 10.1038/sj.cdd.4400783
-
Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000; 7:1166-73. (Pubitemid 32042223)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.12
, pp. 1166-1173
-
-
Korsmeyer, S.J.1
Wei, M.C.2
Saito, M.3
Weiler, S.4
Oh, K.J.5
Schlesinger, P.H.6
-
45
-
-
33746827856
-
Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration
-
DOI 10.1073/pnas.0603007103
-
Munoz-Pinedo C, Guio-Carrion A, Goldstein JC, Fitzgerald P, Newmeyer DD, Green DR. Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration. Proc Natl Acad Sci USA 2006; 103:11573-8. (Pubitemid 44182493)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.31
, pp. 11573-11578
-
-
Munoz-Pinedo, C.1
Guio-Carrion, A.2
Goldstein, J.C.3
Fitzgerald, P.4
Newmeyer, D.D.5
Green, D.R.6
-
46
-
-
10644244369
-
AIF deficiency compromises oxidative phosphorylation
-
Vahsen N, Cande C, Briere JJ, Benit P, Joza N, Larochette N, et al. AIF deficiency compromises oxidative phosphorylation. EMBO J 2004; 23:4679-89.
-
(2004)
EMBO J
, vol.23
, pp. 4679-4689
-
-
Vahsen, N.1
Cande, C.2
Briere, J.J.3
Benit, P.4
Joza, N.5
Larochette, N.6
-
47
-
-
10244241834
-
Deadly conversations: Nuclear-mitochondrial cross-talk
-
Dawson VL, Dawson TM. Deadly conversations: nuclear-mitochondrial cross-talk. J Bioenerg Biomembr 2004; 36:287-94.
-
(2004)
J Bioenerg Biomembr
, vol.36
, pp. 287-294
-
-
Dawson, V.L.1
Dawson, T.M.2
-
48
-
-
69149109036
-
AIF: Not just an apoptosis-inducing factor
-
Joza N, Pospisilik JA, Hangen E, Hanada T, Modjtahedi N, Penninger JM, et al. AIF: not just an apoptosis-inducing factor. Ann N Y Acad Sci 2009; 1171:2-11.
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 2-11
-
-
Joza, N.1
Pospisilik, J.A.2
Hangen, E.3
Hanada, T.4
Modjtahedi, N.5
Penninger, J.M.6
-
49
-
-
33748341710
-
Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis
-
Cheung EC, Joza N, Steenaart NA, McClellan KA, Neuspiel M, McNamara S, et al. Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis. EMBO J 2006; 25:4061-73.
-
(2006)
EMBO J
, vol.25
, pp. 4061-4073
-
-
Cheung, E.C.1
Joza, N.2
Steenaart, N.A.3
McClellan, K.A.4
Neuspiel, M.5
McNamara, S.6
-
50
-
-
33646554500
-
AIFsh, a novel apoptosis-inducing factor (AIF) pro-apoptotic isoform with potential pathological relevance in human cancer
-
DOI 10.1074/jbc.M509884200
-
Delettre C, Yuste VJ, Moubarak RS, Bras M, Lesbordes-Brion JC, Petres S, et al. AIFsh, a Novel Apoptosis-inducing Factor (AIF) Pro-apoptotic Isoform with Potential Pathological Relevance in Human Cancer. J Biol Chem 2006; 281:6413-27. (Pubitemid 43847573)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.10
, pp. 6413-6427
-
-
Delettre, C.1
Yuste, V.J.2
Moubarak, R.S.3
Bras, M.4
Lesbordes-Brion, J.-C.5
Petres, S.6
Bellalou, J.7
Susin, S.A.8
-
51
-
-
33745864801
-
Identification and characterization of AIFsh2, a mitochondrial apoptosis-inducing factor (AIF) isoform with NADH oxidase activity
-
DOI 10.1074/jbc.M601751200
-
Delettre C, Yuste VJ, Moubarak RS, Bras M, Robert N, Susin SA. Identification and Characterization of AIFsh2, a Mitochondrial Apoptosis-inducing Factor (AIF) Isoform with NADH Oxidase Activity. J Biol Chem 2006; 281:18507-18. (Pubitemid 44035510)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.27
, pp. 18507-18518
-
-
Delettre, C.1
Yuste, V.J.2
Moubarak, R.S.3
Bras, M.4
Robert, N.5
Susin, S.A.6
-
52
-
-
1642491755
-
Mitochondrial effectors in caspase-independent cell death
-
DOI 10.1016/S0014-5793(03)01464-9
-
Lorenzo HK, Susin SA. Mitochondrial effectors in caspase-independent cell death. FEBS Lett 2004; 557:14-20. (Pubitemid 38115862)
-
(2004)
FEBS Letters
, vol.557
, Issue.1-3
, pp. 14-20
-
-
Lorenzo, H.K.1
Susin, S.A.2
-
53
-
-
0035844170
-
NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor
-
DOI 10.1074/jbc.M010498200
-
Miramar MD, Costantini P, Ravagnan L, Saraiva LM, Haouzi D, Brothers G, et al. NADH oxidase activity of mitochondrial apoptosis-inducing factor. J Biol Chem 2001; 276:16391-8. (Pubitemid 37391685)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.19
, pp. 16391-16398
-
-
Miramar, M.D.1
Costantini, P.2
Ravagnan, L.3
Saraiva, L.M.4
Haouzi, D.5
Brothers, G.6
Penninger, J.M.7
Peleato, M.L.8
Kroemer, G.9
Susin, S.A.10
-
54
-
-
27444441304
-
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis
-
DOI 10.1074/jbc.M504015200
-
Yuste VJ, Sanchez-Lopez I, Sole C, Moubarak RS, Bayascas JR, Dolcet X, et al. The contribution of apoptosis-inducing factor, caspase-activated DNase and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA. J Biol Chem 2005; 280:35670-83. (Pubitemid 41532760)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35670-35683
-
-
Yuste, V.J.1
Sanchez-Lopez, I.2
Sole, C.3
Moubarak, R.S.4
Bayascas, J.R.5
Dolcet, X.6
Encinas, M.7
Susin, S.A.8
Comella, J.X.9
-
55
-
-
10044224443
-
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death
-
Wang H, Yu SW, Koh DW, Lew J, Coombs C, Bowers W, et al. Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. J Neurosci 2004; 24:10963-73.
-
(2004)
J Neurosci
, vol.24
, pp. 10963-10973
-
-
Wang, H.1
Yu, S.W.2
Koh, D.W.3
Lew, J.4
Coombs, C.5
Bowers, W.6
-
56
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
DOI 10.1101/gad.1199904
-
Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004; 18:1272-82. (Pubitemid 38720595)
-
(2004)
Genes and Development
, vol.18
, Issue.11
, pp. 1272-1282
-
-
Zong, W.-X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.-Q.4
Thompson, C.B.5
-
57
-
-
67649491430
-
Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos)
-
Wang Y, Kim NS, Li X, Greer PA, Koehler RC, Dawson VL, et al. Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos). J Neurochem 2009; 110:687-96.
-
(2009)
J Neurochem
, vol.110
, pp. 687-696
-
-
Wang, Y.1
Kim, N.S.2
Li, X.3
Greer, P.A.4
Koehler, R.C.5
Dawson, V.L.6
-
58
-
-
33845301167
-
Poly(ADP-ribose) (PAR) polymer is a death signal
-
Andrabi SA, Kim NS, Yu SW, Wang H, Koh DW, Sasaki M, et al. Poly(ADP-ribose) (PAR) polymer is a death signal. Proc Natl Acad Sci USA 2006; 103:18308-13.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18308-18313
-
-
Andrabi, S.A.1
Kim, N.S.2
Yu, S.W.3
Wang, H.4
Koh, D.W.5
Sasaki, M.6
-
59
-
-
4644307600
-
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase
-
DOI 10.1038/sj.bjp.0705914
-
Fonfria E, Marshall IC, Benham CD, Boyfield I, Brown JD, Hill K, et al. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase. Br J Pharmacol 2004; 143:186-92. (Pubitemid 39280038)
-
(2004)
British Journal of Pharmacology
, vol.143
, Issue.1
, pp. 186-192
-
-
Fonfria, E.1
Marshall, I.C.B.2
Benham, C.D.3
Boyfield, I.4
Brown, J.D.5
Hill, K.6
Hughes, J.P.7
Skaper, S.D.8
McNulty, S.9
-
60
-
-
54049118472
-
The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes
-
Buelow B, Song Y, Scharenberg AM. The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes. J Biol Chem 2008; 283:24571-83.
-
(2008)
J Biol Chem
, vol.283
, pp. 24571-24583
-
-
Buelow, B.1
Song, Y.2
Scharenberg, A.M.3
-
61
-
-
33646554494
-
The role of TRP channels in oxidative stress-induced cell death
-
Miller BA. The role of TRP channels in oxidative stress-induced cell death. J Membr Biol 2006; 209:31-41.
-
(2006)
J Membr Biol
, vol.209
, pp. 31-41
-
-
Miller, B.A.1
-
62
-
-
57149136324
-
GammaH2AX and cancer
-
Bonner WM, Redon CE, Dickey JS, Nakamura AJ, Sedelnikova OA, Solier S, et al. GammaH2AX and cancer. Nat Rev Cancer 2008; 8:957-67.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 957-967
-
-
Bonner, W.M.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Sedelnikova, O.A.5
Solier, S.6
-
63
-
-
0036531895
-
Histone H2A variants H2AX and H2AZ
-
DOI 10.1016/S0959-437X(02)00282-4
-
Redon C, Pilch D, Rogakou E, Sedelnikova O, Newrock K, Bonner W. Histone H2A variants H2AX and H2AZ. Curr Opin Genet Dev 2002; 12:162-9. (Pubitemid 34219488)
-
(2002)
Current Opinion in Genetics and Development
, vol.12
, Issue.2
, pp. 162-169
-
-
Redon, C.1
Pilch, D.2
Rogakou, E.3
Sedelnikova, O.4
Newrock, K.5
Bonner, W.6
-
64
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273:5858-68.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
65
-
-
0041732381
-
Characteristics of gamma-H2AX foci at DNA double-strand breaks sites
-
DOI 10.1139/o03-042
-
Pilch DR, Sedelnikova OA, Redon C, Celeste A, Nussenzweig A, Bonner WM. Characteristics of gamma-H2AX foci at DNA double-strand breaks sites. Biochem Cell Biol 2003; 81:123-9. (Pubitemid 37076234)
-
(2003)
Biochemistry and Cell Biology
, vol.81
, Issue.3
, pp. 123-129
-
-
Pilch, D.R.1
Sedelnikova, O.A.2
Redon, C.3
Celeste, A.4
Nussenzweig, A.5
Bonner, W.M.6
-
66
-
-
0141740426
-
Focusing on foci: H2AX and the recruitment of DNA-damage response factors
-
Fernandez-Capetillo O, Celeste A, Nussenzweig A. Focusing on foci: H2AX and the recruitment of DNA-damage response factors. Cell Cycle 2003; 2:426-7.
-
(2003)
Cell Cycle
, vol.2
, pp. 426-427
-
-
Fernandez-Capetillo, O.1
Celeste, A.2
Nussenzweig, A.3
-
67
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
DOI 10.1038/ncb1004
-
Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 2003; 5:675-9. (Pubitemid 36818091)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.7
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
Bonner, R.F.7
Bonner, W.M.8
Nussenzweig, A.9
-
68
-
-
33745487368
-
Cell Apoptosis: Requirement of H2AX in DNA Ladder Formation, but Not for the Activation of Caspase-3
-
DOI 10.1016/j.molcel.2006.05.023, PII S1097276506003388
-
Lu C, Zhu F, Cho YY, Tang F, Zykova T, Ma WY, et al. Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3. Mol Cell 2006; 23:121-32. (Pubitemid 43963445)
-
(2006)
Molecular Cell
, vol.23
, Issue.1
, pp. 121-132
-
-
Lu, C.1
Zhu, F.2
Cho, Y.-Y.3
Tang, F.4
Zykova, T.5
Ma, W.-Y.6
Bode, A.M.7
Dong, Z.8
-
69
-
-
0034737439
-
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
-
DOI 10.1074/jbc.275.13.9390
-
Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J Biol Chem 2000; 275:9390-5. (Pubitemid 30185164)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.13
, pp. 9390-9395
-
-
Rogakou, E.P.1
Nieves-Neira, W.2
Boon, C.3
Pommier, Y.4
Bonner, W.M.5
-
72
-
-
33745934311
-
H2AX is a target of the JNK signaling pathway that is required for apoptotic DNA fragmentation
-
Sluss HK, Davis RJ. H2AX is a target of the JNK signaling pathway that is required for apoptotic DNA fragmentation. Mol Cell 2006; 23:152-3.
-
(2006)
Mol Cell
, vol.23
, pp. 152-153
-
-
Sluss, H.K.1
Davis, R.J.2
-
73
-
-
0037159784
-
Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
-
Wang X, Yang C, Chai J, Shi Y, Xue D. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science 2002; 298:1587-92.
-
(2002)
Science
, vol.298
, pp. 1587-1592
-
-
Wang, X.1
Yang, C.2
Chai, J.3
Shi, Y.4
Xue, D.5
-
74
-
-
34447529458
-
BUB1 mediation of caspase-independent mitotic death determines cell fate
-
DOI 10.1083/jcb.200702134
-
Niikura Y, Dixit A, Scott R, Perkins G, Kitagawa K. BUB1 mediation of caspase-independent mitotic death determines cell fate. J Cell Biol 2007; 178:283-96. (Pubitemid 47076464)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.2
, pp. 283-296
-
-
Niikura, Y.1
Dixit, A.2
Scott, R.3
Perkins, G.4
Kitagawa, K.5
-
75
-
-
0030972976
-
Native recombinant cyclophilins A, B and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis
-
Montague JW, Hughes FM Jr, Cidlowski JA. Native recombinant cyclophilins A, B and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. J Biol Chem 1997; 272:6677-84.
-
(1997)
J Biol Chem
, vol.272
, pp. 6677-6684
-
-
Montague, J.W.1
Hughes Jr., F.M.2
Cidlowski, J.A.3
-
76
-
-
34547759778
-
Cyclophilin a participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia
-
Zhu C, Wang X, Deinum J, Huang Z, Gao J, Modjtahedi N, et al. Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia. J Exp Med 2007; 204:1741-8.
-
(2007)
J Exp Med
, vol.204
, pp. 1741-1748
-
-
Zhu, C.1
Wang, X.2
Deinum, J.3
Huang, Z.4
Gao, J.5
Modjtahedi, N.6
-
77
-
-
1542426641
-
AIF and cyclophilin a cooperate in apoptosis-associated chromatinolysis
-
Cande C, Vahsen N, Kouranti I, Schmitt E, Daugas E, Spahr C, et al. AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogene 2004; 23:1514-21.
-
(2004)
Oncogene
, vol.23
, pp. 1514-1521
-
-
Cande, C.1
Vahsen, N.2
Kouranti, I.3
Schmitt, E.4
Daugas, E.5
Spahr, C.6
-
78
-
-
33645026198
-
Physical interaction of apoptosis-inducing factor with DNA and RNA
-
Vahsen N, Cande C, Dupaigne P, Giordanetto F, Kroemer RT, Herker E, et al. Physical interaction of apoptosis-inducing factor with DNA and RNA. Oncogene 2006; 25:1763-74.
-
(2006)
Oncogene
, vol.25
, pp. 1763-1774
-
-
Vahsen, N.1
Cande, C.2
Dupaigne, P.3
Giordanetto, F.4
Kroemer, R.T.5
Herker, E.6
-
79
-
-
52949109178
-
Histone H2AX is a critical factor for cellular protection against DNA alkylating agents
-
Meador JA, Zhao M, Su Y, Narayan G, Geard CR, Balajee AS. Histone H2AX is a critical factor for cellular protection against DNA alkylating agents. Oncogene 2008; 27:5662-71.
-
(2008)
Oncogene
, vol.27
, pp. 5662-5671
-
-
Meador, J.A.1
Zhao, M.2
Su, Y.3
Narayan, G.4
Geard, C.R.5
Balajee, A.S.6
-
81
-
-
76149132685
-
Generic binding sites, generic DNA-binding domains: Where does specific promoter recognition come from?
-
Georges AB, Benayoun BA, Caburet S, Veitia RA. Generic binding sites, generic DNA-binding domains: where does specific promoter recognition come from? FASEB J 24:346-56.
-
FASEB J
, vol.24
, pp. 346-356
-
-
Georges, A.B.1
Benayoun, B.A.2
Caburet, S.3
Veitia, R.A.4
-
82
-
-
0033596980
-
An APAF-1. cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou H, Li Y, Liu X, Wang X. An APAF-1. cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 1999; 274:11549-56. (Pubitemid 129518401)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.17
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
83
-
-
0034105784
-
Apaf-1 oligomerizes into biologically active ~700-kDa and inactive ~1.4-MDa apoptosome complexes
-
DOI 10.1074/jbc.275.9.6067
-
Cain K, Bratton SB, Langlais C, Walker G, Brown DG, Sun XM, et al. Apaf-1 oligomerizes into biologically active approximately 700 kDa and inactive approximately 1.4-MDa apoptosome complexes. J Biol Chem 2000; 275:6067-70. (Pubitemid 30129888)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.9
, pp. 6067-6070
-
-
Cain, K.1
Bratton, S.B.2
Langlais, C.3
Walker, G.4
Brown, D.G.5
Sun, X.-M.6
Cohen, G.M.7
-
84
-
-
0037925454
-
CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation
-
Parrish JZ, Yang C, Shen B, Xue D. CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation. EMBO J 2003; 22:3451-60.
-
(2003)
EMBO J
, vol.22
, pp. 3451-3460
-
-
Parrish, J.Z.1
Yang, C.2
Shen, B.3
Xue, D.4
-
85
-
-
0348109491
-
Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity
-
DOI 10.1016/j.nbd.2003.08.008
-
Yu SW, Wang H, Dawson TM, Dawson VL. Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity. Neurobiol Dis 2003; 14:303-17. (Pubitemid 37543510)
-
(2003)
Neurobiology of Disease
, vol.14
, Issue.3
, pp. 303-317
-
-
Yu, S.-W.1
Wang, H.2
Dawson, T.M.3
Dawson, V.L.4
-
86
-
-
19444374556
-
Mediation of cell death by poly(ADP-ribose) polymerase-1
-
Koh DW, Dawson TM, Dawson VL. Mediation of cell death by poly(ADP-ribose) polymerase-1. Pharmacol Res 2005; 52:5-14.
-
(2005)
Pharmacol Res
, vol.52
, pp. 5-14
-
-
Koh, D.W.1
Dawson, T.M.2
Dawson, V.L.3
-
87
-
-
33746285812
-
Information-driven protein-DNA docking using HADDOCK: It is a matter of flexibility
-
van Dijk M, van Dijk AD, Hsu V, Boelens R, Bonvin AM. Information-driven protein-DNA docking using HADDOCK: it is a matter of flexibility. Nucleic Acids Res 2006; 34:3317-25.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3317-3325
-
-
Van Dijk, M.1
Van Dijk, A.D.2
Hsu, V.3
Boelens, R.4
Bonvin, A.M.5
|