Induction of p21(WAF1/CIP1/SD11) in kidney tubule cells affects the course of cisplatin-induced acute renal failure

Journal of Clinical Investigation

Volumn 101, Issue 4, 1998, Pages 777-782

  Megyesi, Judit ^a   Safirstein, Robert L ^a   Price, Peter M ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Apoptosis; Cell cycle; Cyclin dependent kinase; DNA damage; Necrosis

Indexed keywords

BROXURIDINE; CISPLATIN; CYCLINE; DNA; MESSENGER RNA; NITROGEN; PROTEIN P21; UREA; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ACUTE KIDNEY FAILURE; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; GENE; GENE DELETION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY FUNCTION; KIDNEY TUBULE CELL; MALE; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SOUTHERN BLOTTING; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; CYTOLOGY; GENETICS; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; UREA NITROGEN BLOOD LEVEL;

ANIMALS; BLOOD UREA NITROGEN; CELL CYCLE; CISPLATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; GENE DELETION; KIDNEY FAILURE, ACUTE; KIDNEY TUBULES; MALE; MICE;

EID: 0032519006     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1497     Document Type: Article

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