Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

Journal of Biological Chemistry

Volumn 274, Issue 30, 1999, Pages 21155-21161

  Kirsch, David G ^a   Doseff, Andrea ^b   Chau, B Nelson ^a   Dae Sik, Lim ^a,d   De Souza Pinto, Nadja C ^c   Hansford, Richard ^c   Kastan, Michael B ^a,d   Lazebnik, Yuri A ^b   Hardwick, J Marie ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Watson School of Biological Sciences   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOCHROME C; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IONIZING RADIATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN SECRETION;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CRICETINAE; CYTOCHROME C GROUP; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; SUBSTRATE SPECIFICITY;

CRICETINAE; MINK CELL FOCUS-FORMING VIRUS;

EID: 0033597785     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.30.21155     Document Type: Article

References (46)

1. Salvesen, G. S., and Dixit, V. M. (1997) Cell 91, 443-446
2. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A. Roy, S., Vaillancourt, J. P. Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
3. Boldin, M. P., Goncharov, T. M., Goltsev, Y. V., and Wallach, D. (1996) Cell 85, 803-815
4. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 85, 817-827
5. Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14486-14491
6. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998) Cell 94, 481-490
7. Li, H., Zhu, H., Xu, C.-j., and Yuan, J. (1998) Cell 94, 491-501
8. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cell 91, 497-489
9. Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M. C., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. D., and Wong, W. W. (1997) J. Biol. Chem. 272, 9677-9682
10. Duan, H., and Dixit, V. M. (1997) Nature 385, 86-89
11. Takahashi, A., Alnemri, E. S., Lazebnik, Y. A., Fernandes-Alnemri, T., Litwack, G., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., and Earnshaw, W. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8395-8400
12. Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karaauyama, H., Rakic, P., and Flavell, R. (1996) Nature 384, 368-372
13. Woo, M., Hakem, R., Soengas, M. S., Duncan, G. S., Shahinian, A., Kagi, D., Hakem, A., McCurrach, M., Khoo, W., Kaufmann, S. A., Senaldi, G., Howard, T., Lowe, S. W., and Mak, T. W. (1998) Genes Dev. 12, 806-819
14. Janicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998) J. Biol. Chem. 273, 9357-9360
15. Liu, X., Zou, H., Slaughter, C., and Wang, X. (1997) Cell 89, 175-184
16. Sakahira, H., Enari, M., and Nagata, S. (1998) Nature 391, 96-99
17. Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., and Nagata, S. (1998) Nature 391, 43-50
18. Zhivotovsky, B., Burgess, D. H., Vanags, D. M., and Orrenius, S. (1997) Biochem. Biophys. Res. Commun. 230, 481-488
19. Levkau, B., Koyama, H., Raines, E. W., Clurman, B. E., Herren, B., Orth, K., Roberts, J. M., and Ross, R. (1998) Mol. Cell 1, 553-563
20. Rudel, T., and Bokoch., G. M. (1997) Science 276, 1571-1574
21. Kothakota, S., Azuma, T., Reinhard, C., Klippel, A., Tang, J., Chu, K. T., Mcgarry, T. J., Kirschner, M. W., Koths, K., Kwiatkowski, D. J., and Williams L. T. (1997) Science 278, 294-298
22. Cheng, E. H.-Y., Kirsch, D. G., Clem, R. J., Ravi, R., Kastan, M. B., Bedi, A., Ueno K., and Hardwick, J. M. (1997) Science 278, 1966-1968
23. Grandgirard, D., Studer, E., Monney, L., Belser, T., Fellay, I., Borner, C., and Michel, M. R. (1998) EMBO J. 17, 1268-1278
24. Clem, R. J., Cheng, E. H.-Y., Karp, C. L., Kirsch, D. G., Ueno, K., Takahashi, A., Kastan, M. B., Griffin, D. E., Earnshaw, W. C., Veliuona, M. A., and Hardwick, J. M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 554-559
25. Widmann, C., Gibson, S., and Johnson, G. L. (1998) J. Biol. Chem. 273, 7141-7147
26. Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A., and Yuan J. (1993) Cell 75, 653-660
27. Cheng, E. H.-Y., Nicholas, J., Bellows, D. S., Hayward, G. S., Guo, H.-G., Reitz, M. S., and Hardwick, J. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 690-694
28. Lim, D.-S., Kirsch, D. G., Canman, C. E., Ahn, J.-H., Ziv, Y. Newman, L. S., Darnell, R. B., Shiloh, Y., and Kastan, M. B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 10146-10151
29. Fearnhead, H. O., McCurrach, M. E., O'Neill, J., Zhang, K., Lowe, S. W., and Lazebnik, Y. A. (1997) Genes Dev. 11, 1266-1276
30. Goldman, S. C., Chen, C. Y., Lansing, T. J., Gilmer, T. M., and Kastan, M. B. (1996) Am. J. Pathol. 148, 1381-1385
31. Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., and Fornace, A. J. (1992) Cell 71, 587-597
32. Rosse, T., Olivier, R., Monney, L., Rager, M., Conus, S., Fellay, I., Jansen, B., and Borner, C. (1998) Nature 391, 496-499
33. Hirata, H., Takahashi, A., Kobayashi, S., Yonehara, S., Sawai, H, Okazaki, T., Yamamoto, K., and Sasada, M. (1998) J. Exp. Med. 187, 587-600
34. Tanaka, S., Louie, D. C., Kant, J. A., and Reed, J. C. (1992) Blood 79,229-237
35. Wood, D. E., Thomas, A., Devi, L. A., Berman, Y., Beavis, R. C., Reed, J. C., and Newcomb, E. W. (1998) Oncogene 17, 1069-1078
36. Thomas, A., El Rouby, S., Reed, J. C., Krajewski, S., Silber, R., Potmesil, M., and Newcomb, E. W. (1996) Oncogene 12, 1055-1062
37. Maravei, D. V., Trbovich, A. M., Perez, G. I., Tilly, K. I., Talanian, R. V., Wong, W. W., and Tilly, J. L. (1997) Cell Death Differ. 4, 707-712
38. Li, F., Srinivasan, A., Wang, Y., Armstrong, R. C., Tomaselli, K. J., and Fritz, L. C. (1997) J. Biol. Chem. 272, 30299-30305
39. Reed, J. C. (1997) Nature 387, 773-776
40. Liu, X., Kin, C. N., Yang, J., Jemmerson, R., and Wang, X. (1996) Cell 86, 147-157
41. Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. (1997) Science 275, 1132-1136
42. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., and Wang, X. (1997) Science 275, 1129-1132
43. Hanada, M., Aimé-Sempé, C., Sato, T., and Reed, J. C. (1995) J. Biol. Chem. 270, 11962-11969
44. Hunter, J. J., Bond, B. L., and Parslow, T. G. (1996) Mol. Cell. Biol. 16, 877-883
45. Huang, D. C. S., Adams, J. M., and Cory, S. (1998) EMBO J. 17, 1029-1039
46. Tsujimoto, Y., and Croce, C. M. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 5214-5218