The glucose-regulated proteins: Stress induction and clinical applications

Trends in Biochemical Sciences

Volumn 26, Issue 8, 2001, Pages 504-510

  Lee, Amy S ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; UNCLASSIFIED DRUG;

CANCER CHEMOTHERAPY; CELL SURVIVAL; ENDOPLASMIC RETICULUM; GENE THERAPY; GENETIC TRANSCRIPTION; HUMAN; IMMUNOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN INDUCTION; REVIEW; STRESS;

ANIMALS; GENE EXPRESSION REGULATION; GENE THERAPY; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOTHERAPY; MEMBRANE PROTEINS; NEOPLASMS; OXIDATIVE STRESS; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC;

EID: 0035423875     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)01908-9     Document Type: Review

References (58)

1. Role of the heat shock response and molecular chaperones in oncogenesis and cell death
2. Mammalian stress response: Induction of the glucose-regulated protein family
3. The glucose-regulated proteins (GRP78 and GRP94): Functions, gene regulation, and applications
4. Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
5. Glucose depletion accounts for the induction of two transformation-sensitive membrane proteins in Rous Sarcoma virus-transformed chick embryo fibroblasts
6. 2+-ATPase inhibitor thapsigargin
7. Interaction of ethanol with inducers of glucose-regulated stress proteins. Ethanol potentiates inducers of grp78 transcription
8. Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78
9. Glucose-regulated protein 78 (GRP78) is elevated in embryonic mouse heart and induced following hypoglycemic stress
10. Induction of glucose-regulated protein 78 in rat uterine glandular epithelium during uterine sensitization for the decidual cell reaction
11. Induction of glucose-regulated protein (glucose-regulated protein 78/BiP and glucose-regulated protein 94) and heat shock protein 70 transcripts in the immature rat brain following status epilepticus
12. Use of the glucose-starvation inducible grp78 promoter in suicide gene therapy of murine fibrosarcoma
13. Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells
14. Conservation and divergence of the yeast and mammalian unfolded protein response. Activation of specific mammalian endoplasmic reticulum stress element of the grp78/BiP promoter by yeast Hac1
15. The sarco/endoplasmic reticulum calcium-ATPase 2β is an endoplasmic reticulum stress-inducible protein
16. The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response
17. IRE1 and efferent signaling from the endoplasmic reticulum
18. Involvement of c-Fos in signaling grp78 induction following ER calcium release
19. Mechanism for the suppression of the mammalian stress response by genistein, an anticancer phytoestrogen from soy
20. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors
21. The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex
22. Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress
23. NF-Y, a CCAAT box-binding protein, is one of the trans-acting factors necessary for the response of the murine ERp72 gene to protein traffic
24. Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6α and 6β that activates the mammalian unfolded protein response
25. 2+ depletion and formation of aberrant proteins: Activation of the conserved stress-inducible grp core promoter element by the human nuclear factor YY1
26. Suppression of grp78 core promoter element-mediated stress induction by the dbpA and dbpB (YB-1) cold shock domain proteins
27. Identification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: Its autoregulation by stress and interaction with ATF6
28. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
29. Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic
30. Brefeldin A as a regulator of grp78 gene expression in mammalian cells
31. ATF6 as a transcription activator of the endoplasmic reticulum stress element: Thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1
32. p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6
33. Endoplasmic reticulum oxidoreductin 1-lβ (ERO1-Lβ), a human gene induced in the course of the unfolded protein response
34. Adapt78 protects cells against stress damage and suppresses cell growth
35. The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins
36. Activation of the unfolded protein response pathway induces human asparagine synthetase gene expression
37. Generation of a mammalian cell line deficient in glucose-regulated protein stress induction through targeted ribozyme driven by a stress-inducible promoter
38. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME
39. Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction
40. 2+ disturbances, and cell death in renal epithelial cells
41. Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins
42. 2+-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis
43. Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells
44. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
45. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
46. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression
47. The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome
48. Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions
49. p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2
50. Drug resistance mediated by cellular stress response to the microenvironment of solid tumors
51. Increased sensitivity of human colon cancer cells to DNA cross-linking agents after GRP78 up-regulation
52. CD91: A receptor for heat shock protein gp96
53. Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: A pilot study
54. Characterization of heat shock protein 110 and glucose regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity
55. Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter
56. Glucose regulated protein induction and cellular resistance to oxidative stress mediated by porphyrin photosensitization
57. The protein disulphide-isomerase family: Unravelling a string of folds
58. Glycoprotein folding in the endoplasmic reticulum: A tale of three chaperones?