Retinoid-related molecules require caspase 9 for the effective release of Smac and the rapid induction of apoptosis

Cell Death and Differentiation

Volumn 11, Issue 2, 2004, Pages 154-164

  Lopez Hernandez, F J ^a   Ortiz, M A ^a   Piedrafita, F J ^a  

^a SIDNEY KIMMEL CANCER CENTER   (United States)

Author keywords

Caspase 9; Growth arrest; Retinoids; Smac

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; MITOCHONDRIAL ENZYME; MX 2870 1; MX 781; PROTEIN BCL 2; PROTEIN BCL XL; RETINOID DERIVATIVE; RETINOID X RECEPTOR; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER THERAPY; CATALYSIS; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME RELEASE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MUTANT; PRIORITY JOURNAL; PROTEIN SECRETION;

APOPTOSIS; BCL-X PROTEIN; CARRIER PROTEINS; CASPASE 2; CASPASE 9; CASPASES; CELL CYCLE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; KINETICS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RETINOIDS;

EID: 0742272017     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401329     Document Type: Article

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