Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

Biochemical Journal

Volumn 407, Issue 1, 2007, Pages 49-59

  Van Den Berghe, Peter V E ^a   Folmer, Dineke E ^a   Malingré, Helga E M ^a   Van Beurden, Ellen ^a   Klomp, Adriana E M ^a   Van De Sluis, Bart ^a   Merkx, Maarten ^b   Berger, Ruud ^a   Klomp, Leo W J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Copper biosensor; Copper transporter 1 (Ctr1); Copper transporter 2 (Ctr2); Copper uptake; Metallothionein; Zinc

Indexed keywords

COPPER BIOSENSORS; COPPER TRANSPORTER 1 (CTR1); COPPER TRANSPORTER 2 (CTR2); COPPER UPTAKE; METALLOTHIONEIN;

CELL CULTURE; CELL MEMBRANES; COMPLEXATION; COPPER; MOLECULAR WEIGHT;

ENZYMES;

COPPER; LUCIFERASE; MENKES PROTEIN; METALLOTHIONEIN I; WILSON DISEASE PROTEIN;

ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COPPER METABOLISM; CROSS LINKING; ENDOSOME; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LYSOSOME; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; CELL MEMBRANE; CELLS, CULTURED; COPPER; CYTOSOL; ENDOSOMES; HELA CELLS; HUMANS; LYSOSOMES; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; TRANSFECTION;

EID: 35148829094     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070705     Document Type: Article

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