메뉴 건너뛰기




Volumn 13, Issue 4, 2011, Pages 223-250

Oxidative stress and β-amyloid protein in Alzheimer's disease

Author keywords

Alzheimer's disease; B Amyloid protein; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CHEMOKINE; CLIOQUINOL; GAMMA SECRETASE; INTERLEUKIN 1; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SECRETASE; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84855866955     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-011-8155-9     Document Type: Review
Times cited : (231)

References (411)
  • 1
    • 0141761461 scopus 로고    scopus 로고
    • Role of cytokines in neurological disorders
    • DOI 10.2174/0929867033456918
    • Aarli, J. A. (2003). Role of cytokines in neurological disorders. Current Medicinal Chemistry, 10, 1931-1937. (Pubitemid 37139055)
    • (2003) Current Medicinal Chemistry , vol.10 , Issue.19 , pp. 1931-1937
    • Aarli, J.A.1
  • 3
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • DOI 10.1038/nrn1824
    • Abbott, N. J., Ronnback, L., & Hansson, E. (2006). Astrocyte-endothelial interactions at the blood-brain barrier. Nature Reviews. Neuroscience, 7, 41-53. (Pubitemid 41828930)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.1 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 4
    • 1642499152 scopus 로고    scopus 로고
    • β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase
    • DOI 10.1523/JNEUROSCI.4042-03.2004
    • Abramov, A. Y., Canevari, L., & Duchen, M. R. (2004). Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. Journal of Neuroscience, 24, 565-575. (Pubitemid 38112390)
    • (2004) Journal of Neuroscience , vol.24 , Issue.2 , pp. 565-575
    • Abramov, A.Y.1    Canevari, L.2    Duchen, M.R.3
  • 6
    • 0029312921 scopus 로고
    • Aging, disease and nerve cell death
    • discussion 1197-1203
    • Agid, Y. (1995). Aging, disease and nerve cell death. Bulletin de l'Académie Nationale de Médecine, 179, 1193-1203 (discussion 1197-1203).
    • (1995) Bulletin de L'Académie Nationale de Médecine , vol.179 , pp. 1193-1203
    • Agid, Y.1
  • 7
    • 77957970155 scopus 로고    scopus 로고
    • Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease
    • Agostinho, P., Cunha, R. A., & Oliveira, C. (2010). Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease. Current Pharmaceutical Design, 16, 2766-2778.
    • (2010) Current Pharmaceutical Design , vol.16 , pp. 2766-2778
    • Agostinho, P.1    Cunha, R.A.2    Oliveira, C.3
  • 10
    • 0030657456 scopus 로고    scopus 로고
    • Oxidative modification of glutamine synthetase by amyloid beta peptide
    • Aksenov, M. Y., Aksenova, M. V., Carney, J. M., & Butterfield, D. A. (1997). Oxidative modification of glutamine synthetase by amyloid beta peptide. Free Radical Research, 27, 267-281. (Pubitemid 27474886)
    • (1997) Free Radical Research , vol.27 , Issue.3 , pp. 267-281
    • Aksenov, M.Y.1    Aksenova, M.V.2    Carney, J.M.3    Butterfield, D.A.4
  • 12
    • 0023237250 scopus 로고
    • Blood-brain barrier in Alzheimer dementia and in non-demented elderly. An immunocytochemical study
    • DOI 10.1007/BF00693782
    • Alafuzoff, I., Adolfsson, R., Grundke-Iqbal, I., & Winblad, B. (1987). Blood-brain barrier in Alzheimer dementia and in non-demented elderly. An immunocytochemical study. Acta Neuropathologica, 73, 160-166. (Pubitemid 17060012)
    • (1987) Acta Neuropathologica , vol.73 , Issue.2 , pp. 160-166
    • Alafuzoff, I.1    Adolfsson, R.2    Grundke-Iqbal, I.3    Winblad, B.4
  • 14
    • 46749158750 scopus 로고    scopus 로고
    • The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration
    • Alberghina, L., & Colangelo, A. M. (2006). The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration. BMC Neuroscience, 7(Suppl 1), S2.
    • (2006) BMC Neuroscience , vol.7 , Issue.SUPPL. 1
    • Alberghina, L.1    Colangelo, A.M.2
  • 16
    • 79551662777 scopus 로고    scopus 로고
    • Oxidative stress induced-metabolic imbalance, mitochondrial failure, and cellular hypoperfusion as primary pathogenetic factors for the development of Alzheimer disease which can be used as a alternate and successful drug treatment strategy: Past, present and future
    • Aliev, G. (2011). Oxidative stress induced-metabolic imbalance, mitochondrial failure, and cellular hypoperfusion as primary pathogenetic factors for the development of Alzheimer disease which can be used as a alternate and successful drug treatment strategy: Past, present and future. CNS & Neurological Disorders Drug Targets, 10, 147-148.
    • (2011) CNS & Neurological Disorders Drug Targets , vol.10 , pp. 147-148
    • Aliev, G.1
  • 17
    • 0035975602 scopus 로고    scopus 로고
    • Selective increases in cytokine expression in the rat brain in response to striatal injection of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1
    • DOI 10.1016/S0169-328X(01)00211-X, PII S0169328X0100211X
    • Allan, S. M., Harrison, D. C., Read, S., Collins, B., Parsons, A. A., Philpott, K., et al. (2001). Selective increases incytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionate and interleukin-1. Brain Research. Molecular Brain Research, 93, 180-189. (Pubitemid 32925178)
    • (2001) Molecular Brain Research , vol.93 , Issue.2 , pp. 180-189
    • Allan, S.M.1    Harrison, D.C.2    Read, S.3    Collins, B.4    Parsons, A.A.5    Philpott, K.6    Rothwell, N.J.7
  • 18
    • 65449158394 scopus 로고    scopus 로고
    • Antioxidants attenuate hyperglycaemia-mediated brain endothelial cell dysfunction and blood-brain barrier hyperpermeability
    • Allen, C. L., & Bayraktutan, U. (2009a). Antioxidants attenuate hyperglycaemia-mediated brain endothelial cell dysfunction and blood-brain barrier hyperpermeability. Diabetes, Obesity & Metabolism, 11, 480-490.
    • (2009) Diabetes, Obesity & Metabolism , vol.11 , pp. 480-490
    • Allen, C.L.1    Bayraktutan, U.2
  • 19
    • 77449152992 scopus 로고    scopus 로고
    • Oxidative stress and its role in the pathogenesis of ischaemic stroke
    • Allen, C. L., & Bayraktutan, U. (2009b). Oxidative stress and its role in the pathogenesis of ischaemic stroke. International Journal of Stroke, 4, 461-470.
    • (2009) International Journal of Stroke , vol.4 , pp. 461-470
    • Allen, C.L.1    Bayraktutan, U.2
  • 22
    • 33750323814 scopus 로고    scopus 로고
    • In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: Relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders
    • DOI 10.1016/j.freeradbiomed.2006.09.002, PII S0891584906005636
    • Ansari, M. A., Joshi, G., Huang, Q., Opii, W. O., Abdul, H. M., Sultana, R., et al. (2006). In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: Relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders. Free Radical Biology and Medicine, 41, 1694-1703. (Pubitemid 44634240)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.11 , pp. 1694-1703
    • Ansari, M.A.1    Joshi, G.2    Huang, Q.3    Opii, W.O.4    Abdul, H.M.5    Sultana, R.6    Butterfield, D.A.7
  • 23
    • 75949121583 scopus 로고    scopus 로고
    • Oxidative stress in the progression of Alzheimer disease in the frontal cortex
    • Ansari, M. A., & Scheff, S. W. (2010). Oxidative stress in the progression of Alzheimer disease in the frontal cortex. Journal of Neuropathology and Experimental Neurology, 69, 155-167.
    • (2010) Journal of Neuropathology and Experimental Neurology , vol.69 , pp. 155-167
    • Ansari, M.A.1    Scheff, S.W.2
  • 24
    • 4744369310 scopus 로고    scopus 로고
    • Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology
    • DOI 10.1016/j.ijdevneu.2004.07.006, PII S0736574804000929, Molecular Mechanisms of Neurodegeneration and Neuroprotection
    • Apelt, J., Bigl, M., Wunderlich, P., & Schliebs, R. (2004). Agingrelated increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology. International Journal of Developmental Neuroscience, 22, 475-484. (Pubitemid 39311436)
    • (2004) International Journal of Developmental Neuroscience , vol.22 , Issue.7 , pp. 475-484
    • Apelt, J.1    Bigl, M.2    Wunderlich, P.3    Schliebs, R.4
  • 25
    • 0035831189 scopus 로고    scopus 로고
    • β-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
    • DOI 10.1016/S0006-8993(00)03176-0, PII S0006899300031760
    • Apelt, J., & Schliebs, R. (2001). Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. Brain Research, 894, 21-30. (Pubitemid 32197594)
    • (2001) Brain Research , vol.894 , Issue.1 , pp. 21-30
    • Apelt, J.1    Schliebs, R.2
  • 28
    • 3042586648 scopus 로고    scopus 로고
    • Inflammatory mediator and β-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E
    • DOI 10.1016/j.freeradbiomed.2004.04.007, PII S0891584904003107
    • Ayasolla, K., Khan, M., Singh, A. K., & Singh, I. (2004). Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. Free Radical Biology and Medicine, 37, 325-338. (Pubitemid 38833999)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.3 , pp. 325-338
    • Ayasolla, K.1    Khan, M.2    Singh, A.K.3    Singh, I.4
  • 29
    • 78651497015 scopus 로고    scopus 로고
    • Characterization and use of human brain microvascular endothelial cells to examine beta-amyloid exchange in the blood-brain barrier
    • Bachmeier, C., Mullan, M., & Paris, D. (2010). Characterization and use of human brain microvascular endothelial cells to examine beta-amyloid exchange in the blood-brain barrier. Cytotechnology, 62, 519-529.
    • (2010) Cytotechnology , vol.62 , pp. 519-529
    • Bachmeier, C.1    Mullan, M.2    Paris, D.3
  • 30
    • 0029852887 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-β peptide (1-40)
    • Backstrom, J. R., Lim, G. P., Cullen, M. J., & Tokes, Z. A. (1996). Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40). Journal of Neuroscience, 16, 7910-7919. (Pubitemid 26405054)
    • (1996) Journal of Neuroscience , vol.16 , Issue.24 , pp. 7910-7919
    • Backstrom, J.R.1    Lim, G.P.2    Cullen, M.J.3    Tokes, Z.A.4
  • 31
    • 0033961320 scopus 로고    scopus 로고
    • Chemokines and their receptors in neurobiology: Perspectives in physiology and homeostasis
    • DOI 10.1016/S0165-5728(99)00266-0, PII S0165572899002660
    • Bacon, K. B., & Harrison, J. K. (2000). Chemokines and their receptors in neurobiology: Perspectives in physiology and homeostasis. Journal of Neuroimmunology, 104, 92-97. (Pubitemid 30100542)
    • (2000) Journal of Neuroimmunology , vol.104 , Issue.1 , pp. 92-97
    • Bacon, K.B.1    Harrison, J.K.2
  • 32
    • 39249083317 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease
    • Bader Lange, M. L., Cenini, G., Piroddi, M., Abdul, H. M., Sultana, R., Galli, F., et al. (2008). Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiology of Diseases, 29, 456-464.
    • (2008) Neurobiology of Diseases , vol.29 , pp. 456-464
    • Bader Lange, M.L.1    Cenini, G.2    Piroddi, M.3    Abdul, H.M.4    Sultana, R.5    Galli, F.6
  • 33
    • 77549087405 scopus 로고    scopus 로고
    • Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) 9 PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: Relevance to Alzheimer disease
    • Bader Lange, M. L., St. Clair, D., Markesbery, W. R., Studzinski, C. M., Murphy, M. P., & Butterfield, D. A. (2010). Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) 9 PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: Relevance to Alzheimer disease. Neurobiology of Diseases, 38, 104-115.
    • (2010) Neurobiology of Diseases , vol.38 , pp. 104-115
    • Bader Lange, M.L.1    St. Clair, D.2    Markesbery, W.R.3    Studzinski, C.M.4    Murphy, M.P.5    Butterfield, D.A.6
  • 34
    • 0035984815 scopus 로고    scopus 로고
    • Brain clearance of Alzheimer's amyloid-β40 in the squirrel monkey: A SPECT study in a primate model of cerebral amyloid angiopathy
    • DOI 10.1080/10611860290031831
    • Bading, J. R., Yamada, S., Mackic, J. B., Kirkman, L., Miller, C., Calero, M., et al. (2002). Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: A SPECT study in a primate model of cerebral amyloid angiopathy. Journal of Drug Targeting, 10, 359-368. (Pubitemid 34746318)
    • (2002) Journal of Drug Targeting , vol.10 , Issue.4 , pp. 359-368
    • Bading, J.R.1    Yamada, S.2    Mackic, J.B.3    Kirkman, L.4    Miller, C.5    Calero, M.6    Ghiso, J.7    Frangione, B.8    Zlokovic, B.V.9
  • 35
  • 38
    • 78651074925 scopus 로고    scopus 로고
    • Depletion of CXCR2 inhibits gamma-secretase activity and amyloid-beta production in a murine model of Alzheimer's disease
    • Bakshi, P., Margenthaler, E., Reed, J., Crawford, F., & Mullan, M. (2011). Depletion of CXCR2 inhibits gamma-secretase activity and amyloid-beta production in a murine model of Alzheimer's disease. Cytokine, 53, 163-169.
    • (2011) Cytokine , vol.53 , pp. 163-169
    • Bakshi, P.1    Margenthaler, E.2    Reed, J.3    Crawford, F.4    Mullan, M.5
  • 40
    • 0027421612 scopus 로고
    • β-Amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimer's disease
    • DOI 10.1111/j.1749-6632.1993.tb23045.x
    • Barger, S. W., Smith-Swintosky, V. L., Rydel, R. E., & Mattson, M. P. (1993). Beta-amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimer's disease. Annals of the New York Academy of Sciences, 695, 158-164. (Pubitemid 23348254)
    • (1993) Annals of the New York Academy of Sciences , vol.695 , pp. 158-164
    • Barger, S.W.1    Smith-Swintosky, V.L.2    Rydel, R.E.3    Mattson, M.P.4
  • 41
    • 53749102630 scopus 로고    scopus 로고
    • Therapeutic strategies for Alzheimer's disease
    • Barten, D. M., & Albright, C. F. (2008). Therapeutic strategies for Alzheimer's disease. Molecular Neurobiology, 37, 171-186.
    • (2008) Molecular Neurobiology , vol.37 , pp. 171-186
    • Barten, D.M.1    Albright, C.F.2
  • 42
    • 0026776682 scopus 로고
    • Morphological differentiation and proteoglycan synthesis regulate Alzheimer amyloid precursor protein processing in PC-12 and human astrocyte cultures
    • Baskin, F., Rosenberg, R. N., & Davis, R. M. (1992). Morphological differentiation and proteoglycan synthesis regulate Alzheimer amyloid precursor protein processing in PC-12 and human astrocyte cultures. Journal of Neuroscience Research, 32, 274-279.
    • (1992) Journal of Neuroscience Research , vol.32 , pp. 274-279
    • Baskin, F.1    Rosenberg, R.N.2    Davis, R.M.3
  • 43
    • 33646236326 scopus 로고    scopus 로고
    • Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: Synergistic action of estrogen metabolite and ligands of death receptor family
    • Basu, A., Castle, V. P., Bouziane, M., Bhalla, K., & Haldar, S. (2006). Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: Synergistic action of estrogen metabolite and ligands of death receptor family. Cancer Research, 66, 4309-4318.
    • (2006) Cancer Research , vol.66 , pp. 4309-4318
    • Basu, A.1    Castle, V.P.2    Bouziane, M.3    Bhalla, K.4    Haldar, S.5
  • 44
    • 0032865258 scopus 로고    scopus 로고
    • Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients
    • DOI 10.1006/exnr.1999.7151
    • Battaini, F., Pascale, A., Lucchi, L., Pasinetti, G. M., & Govoni, S. (1999). Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients. Experimental Neurology, 159, 559-564. (Pubitemid 29485243)
    • (1999) Experimental Neurology , vol.159 , Issue.2 , pp. 559-564
    • Battaini, F.1    Pascale, A.2    Lucchi, L.3    Pasinetti, G.M.4    Govoni, S.5
  • 45
    • 33745917384 scopus 로고    scopus 로고
    • A vicious circle: Role of oxidative stress, intraneuronal Aβ and Cu in Alzheimer's disease
    • Bayer, T. A., Schafer, S., Breyhan, H., Wirths, O., Treiber, C., & Multhaup, G. (2006). A vicious circle: Role of oxidative stress, intraneuronal Abeta and Cu in Alzheimer's disease. Clinical Neuropathology, 25, 163-171. (Pubitemid 44047901)
    • (2006) Clinical Neuropathology , vol.25 , Issue.4 , pp. 163-171
    • Bayer, T.A.1    Schafer, S.2    Breyhan, H.3    Wirths, O.4    Treiber, C.5    Multhaup, G.6
  • 46
    • 0036254698 scopus 로고    scopus 로고
    • Oxidative nerve cell death in Alzheimer's disease and stroke: Antioxidants as neuroprotective compounds
    • DOI 10.1515/BC.2002.053
    • Behl, C., & Moosmann, B. (2002). Oxidative nerve cell death in Alzheimer's disease and stroke: Antioxidants as neuroprotective compounds. Biological Chemistry, 383, 521-536. (Pubitemid 34506288)
    • (2002) Biological Chemistry , vol.383 , Issue.3-4 , pp. 521-536
    • Behl, C.1    Moosmann, B.2
  • 47
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • Bell, R. D., & Zlokovic, B. V. (2009). Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathologica, 118, 103-113.
    • (2009) Acta Neuropathologica , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 48
    • 2342420427 scopus 로고    scopus 로고
    • Oxygen, reactive oxygen species and tissue damage
    • DOI 10.2174/1381612043384664
    • Bergamini, C. M., Gambetti, S., Dondi, A., & Cervellati, C. (2004). Oxygen, reactive oxygen species and tissue damage. Current Pharmaceutical Design, 10, 1611-1626. (Pubitemid 38559774)
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.14 , pp. 1611-1626
    • Bergamini, C.M.1    Gambetti, S.2    Dondi, A.3    Cervellati, C.4
  • 49
    • 34547438627 scopus 로고    scopus 로고
    • Smoking, oxidative stress and cardiovascular diseases-do anti-oxidative therapies fail?
    • DOI 10.2174/092986707781058959
    • Bernhard, D., & Wang, X. L. (2007). Smoking, oxidative stress and cardiovascular diseases - do anti-oxidative therapies fail? Current Medicinal Chemistry, 14, 1703-1712. (Pubitemid 47163408)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.16 , pp. 1703-1712
    • Bernhard, D.1    Wang, X.L.2
  • 50
    • 50249135503 scopus 로고    scopus 로고
    • Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
    • Bezprozvanny, I., & Mattson, M. P. (2008). Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends in Neurosciences, 31, 454-463.
    • (2008) Trends in Neurosciences , vol.31 , pp. 454-463
    • Bezprozvanny, I.1    Mattson, M.P.2
  • 51
    • 0036848054 scopus 로고    scopus 로고
    • Nitronyl nitroxides, a novel group of protective agents against oxidative stress in endothelial cells forming the blood-brain barrier
    • DOI 10.1016/S0028-3908(02)00180-6, PII S0028390802001806
    • Blasig, I. E., Mertsch, K., & Haseloff, R. F. (2002). Nitronyl nitroxides, a novel group of protective agents against oxidative stress in endothelial cells forming the blood-brain barrier. Neuropharmacology, 43, 1006-1014. (Pubitemid 35341236)
    • (2002) Neuropharmacology , vol.43 , Issue.6 , pp. 1006-1014
    • Blasig, I.E.1    Mertsch, K.2    Haseloff, R.F.3
  • 52
    • 0025734299 scopus 로고
    • The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease
    • Blass, J. P., & Gibson, G. E. (1991). The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease. Revue Neurologique (Paris), 147, 513-525.
    • (1991) Revue Neurologique (Paris) , vol.147 , pp. 513-525
    • Blass, J.P.1    Gibson, G.E.2
  • 53
    • 0024357791 scopus 로고
    • Focusing on IL 1-promotion of β-amyloid precursor protein synthesis as an early event in Alzheimer's disease
    • DOI 10.1016/0197-4580(89)90077-8
    • Blume, A. J., & Vitek, M. P. (1989). Focusing on IL-1-promotion of beta-amyloid precursor protein synthesis as an early event in Alzheimer's disease. Neurobiology of Aging, 10, 406-408 (discussion 404-412). (Pubitemid 19245428)
    • (1989) Neurobiology of Aging , vol.10 , Issue.5 , pp. 406-408
    • Blume, A.J.1    Vitek, M.P.2
  • 54
    • 77955917442 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer disease: A possibility for prevention
    • Bonda, D. J., Wang, X., Perry, G., Nunomura, A., Tabaton, M., Zhu, X., et al. (2010). Oxidative stress in Alzheimer disease: A possibility for prevention. Neuropharmacology, 59, 290-294.
    • (2010) Neuropharmacology , vol.59 , pp. 290-294
    • Bonda, D.J.1    Wang, X.2    Perry, G.3    Nunomura, A.4    Tabaton, M.5    Zhu, X.6
  • 55
    • 33748780095 scopus 로고    scopus 로고
    • Role of complement in neurodegeneration and neuroinflammation
    • DOI 10.1016/j.molimm.2006.03.007, PII S0161589006001222
    • Bonifati, D. M., & Kishore, U. (2007). Role of complement in neurodegeneration and neuroinflammation. Molecular Immunology, 44, 999-1010. (Pubitemid 44414994)
    • (2007) Molecular Immunology , vol.44 , Issue.5 , pp. 999-1010
    • Bonifati, D.M.1    Kishore, U.2
  • 59
    • 34248178463 scopus 로고    scopus 로고
    • Differential regulation of BACE1 promoter activity by nuclear factor-κB in neurons and glia upon exposure to β-amyloid peptides
    • DOI 10.1002/jnr.21252
    • Bourne, K. Z., Ferrari, D. C., Lange-Dohna, C., Rossner, S., Wood, T. G., & Perez-Polo, J. R. (2007). Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides. Journal of Neuroscience Research, 85, 1194-1204. (Pubitemid 46724363)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.6 , pp. 1194-1204
    • Bourne, K.Z.1    Ferrari, D.C.2    Lange-Dohna, C.3    Rossner, S.4    Wood, T.G.5    Perez-Polo, J.R.6
  • 60
    • 33745990556 scopus 로고    scopus 로고
    • Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Aβ(1-42): Implications for Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2005.07.001, PII S0197458005001909
    • Boyd-Kimball, D., Poon, H. F., Lynn, B. C., Cai, J., Pierce, W. M., Jr., Klein, J. B., et al. (2006). Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Abeta(1-42): Implications for Alzheimer's disease. Neurobiology of Aging, 27, 1239-1249. (Pubitemid 44067304)
    • (2006) Neurobiology of Aging , vol.27 , Issue.9 , pp. 1239-1249
    • Boyd-Kimball, D.1    Poon, H.F.2    Lynn, B.C.3    Cai, J.4    Pierce Jr., W.M.5    Klein, J.B.6    Ferguson, J.7    Link, C.D.8    Butterfield, D.A.9
  • 61
    • 0032479929 scopus 로고    scopus 로고
    • Complement-dependent proinflammatory properties of the Alzheimer's disease β-peptide
    • DOI 10.1084/jem.188.3.431
    • Bradt, B. M., Kolb, W. P., & Cooper, N. R. (1998). Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide. Journal of Experimental Medicine, 188, 431-438. (Pubitemid 28369133)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.3 , pp. 431-438
    • Bradt, B.M.1    Kolb, W.P.2    Cooper, N.R.3
  • 62
    • 77956933314 scopus 로고    scopus 로고
    • Soluble TNF receptors are associated with Abeta metabolism and conversion to dementia in subjects with mild cognitive impairment
    • Buchhave, P., Zetterberg, H., Blennow, K., Minthon, L., Janciauskiene, S., & Hansson, O. (2010). Soluble TNF receptors are associated with Abeta metabolism and conversion to dementia in subjects with mild cognitive impairment. Neurobiology of Aging, 31, 1877-1884.
    • (2010) Neurobiology of Aging , vol.31 , pp. 1877-1884
    • Buchhave, P.1    Zetterberg, H.2    Blennow, K.3    Minthon, L.4    Janciauskiene, S.5    Hansson, O.6
  • 63
    • 77955270739 scopus 로고    scopus 로고
    • Beta-amyloid precursor protein metabolism: Focus on the functions and degradation of its intracellular domain
    • Buoso, E., Lanni, C., Schettini, G., Govoni, S., & Racchi, M. (2010). Beta-amyloid precursor protein metabolism: Focus on the functions and degradation of its intracellular domain. Pharmacological Research, 62, 308-317.
    • (2010) Pharmacological Research , vol.62 , pp. 308-317
    • Buoso, E.1    Lanni, C.2    Schettini, G.3    Govoni, S.4    Racchi, M.5
  • 64
    • 0036860349 scopus 로고    scopus 로고
    • Metal complexing agents as therapies for Alzheimer's disease
    • DOI 10.1016/S0197-4580(02)00120-3, PII S0197458002001203
    • Bush, A. I. (2002). Metal complexing agents as therapies for Alzheimer's disease. Neurobiology of Aging, 23, 1031-1038. (Pubitemid 35447784)
    • (2002) Neurobiology of Aging , vol.23 , Issue.6 , pp. 1031-1038
    • Bush, A.I.1
  • 65
    • 8744276616 scopus 로고    scopus 로고
    • Amyloid β-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain
    • Butterfield, D. A., & Boyd-Kimball, D. (2004). Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurode-generation found in Alzheimer disease brain. Brain Pathology, 14, 426-432. (Pubitemid 39524972)
    • (2004) Brain Pathology , vol.14 , Issue.4 , pp. 426-432
    • Butterfield, D.A.1    Boyd-Kimball, D.2
  • 66
    • 74149091007 scopus 로고    scopus 로고
    • In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP
    • Butterfield, D. A., Galvan, V., Lange, M. B., Tang, H., Sowell, R. A., Spilman, P., et al. (2010a). In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP. Free Radical Biology and Medicine, 48, 136-144.
    • (2010) Free Radical Biology and Medicine , vol.48 , pp. 136-144
    • Butterfield, D.A.1    Galvan, V.2    Lange, M.B.3    Tang, H.4    Sowell, R.A.5    Spilman, P.6
  • 67
    • 0036592636 scopus 로고    scopus 로고
    • Amyloid β-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists
    • Butterfield, D. A., Griffin, S., Munch, G., & Pasinetti, G. M. (2002). Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. Journal of Alzheimer's Disease, 4, 193-201. (Pubitemid 35006051)
    • (2002) Journal of Alzheimer's Disease , vol.4 , Issue.3 , pp. 193-201
    • Butterfield, D.A.1    Griffin, S.2    Munch, G.3    Pasinetti, G.M.4
  • 68
    • 77954497959 scopus 로고    scopus 로고
    • Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: Many pathways to neurodegeneration
    • Butterfield, D. A., Hardas, S. S., & Lange, M. L. (2010b). Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: Many pathways to neurodegeneration. Journal of Alzheimer's Disease, 20, 369-393.
    • (2010) Journal of Alzheimer's Disease , vol.20 , pp. 369-393
    • Butterfield, D.A.1    Hardas, S.S.2    Lange, M.L.3
  • 69
    • 0036591849 scopus 로고    scopus 로고
    • Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress
    • DOI 10.1016/S0891-5849(02)00794-3, PII S0891584902007943
    • Butterfield, D. A., & Lauderback, C. M. (2002). Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radical Biology and Medicine, 32, 1050-1060. (Pubitemid 34603342)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.11 , pp. 1050-1060
    • Butterfield D.Allan1    Lauderback, C.M.2
  • 70
    • 0043172479 scopus 로고    scopus 로고
    • The glutamatergic system and Alzheimer's disease: Therapeutic implications
    • DOI 10.2165/00023210-200317090-00004
    • Butterfield, D. A., & Pocernich, C. B. (2003). The glutamatergic system and Alzheimer's disease: Therapeutic implications. CNS Drugs, 17, 641-652. (Pubitemid 36920542)
    • (2003) CNS Drugs , vol.17 , Issue.9 , pp. 641-652
    • Butterfield, D.A.1    Pocernich, C.B.2
  • 71
    • 34547102265 scopus 로고    scopus 로고
    • Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
    • DOI 10.1016/j.freeradbiomed.2007.05.037, PII S0891584907003929
    • Butterfield, D. A., Reed, T., Newman, S. F., & Sultana, R. (2007). Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment. Free Radical Biology and Medicine, 43, 658-677. (Pubitemid 47102132)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.5 , pp. 658-677
    • Butterfield, D.A.1    Reed, T.2    Newman, S.F.3    Sultana, R.4
  • 72
    • 34547131835 scopus 로고    scopus 로고
    • A novel modulatory mechanism of transforming growth factor-β signaling through decorin and LRP-1
    • DOI 10.1074/jbc.M700243200
    • Cabello-Verrugio, C., & Brandan, E. (2007). A novel modulatory mechanism of transforming growth factor-beta signaling through decorin and LRP-1. The Journal of Biological Chemistry, 282, 18842-18850. (Pubitemid 47100183)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.26 , pp. 18842-18850
    • Cabello-Verrugio, C.1    Brandan, E.2
  • 73
    • 0029151132 scopus 로고
    • Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency
    • Calingasan, N. Y., Baker, H., Sheu, K. F., & Gibson, G. E. (1995). Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency. Experimental Neurology, 134, 64-72.
    • (1995) Experimental Neurology , vol.134 , pp. 64-72
    • Calingasan, N.Y.1    Baker, H.2    Sheu, K.F.3    Gibson, G.E.4
  • 74
    • 40849135716 scopus 로고    scopus 로고
    • Apoptotic mechanisms involved in neurodegenerative diseases: Experimental and therapeutic approaches
    • DOI 10.1358/mf.2008.30.1.1090962
    • Camins, A., Pallas, M., & Silvestre, J. S. (2008). Apoptotic mechanisms involved in neurodegenerative diseases: Experimental and therapeutic approaches. Methods and Findings in Experimental and Clinical Pharmacology, 30, 43-65. (Pubitemid 351397455)
    • (2008) Methods and Findings in Experimental and Clinical Pharmacology , vol.30 , Issue.1 , pp. 43-65
    • Camins, A.1    Pallas, M.2    Silvestre, J.S.3
  • 75
    • 0027135969 scopus 로고
    • Divergent transforming growth factor-β effects on IL-6 regulation of acute phase plasma proteins in rat hepatoma cells
    • Campos, S. P., Wang, Y., Koj, A., & Baumann, H. (1993). Divergent transforming growth factor-beta effects on IL-6 regulation of acute phase plasma proteins in rat hepatoma cells. Journal of Immunology, 151, 7128-7137. (Pubitemid 24001087)
    • (1993) Journal of Immunology , vol.151 , Issue.12 , pp. 7128-7137
    • Campos, S.P.1    Wang, Y.2    Koj, A.3    Baumann, H.4
  • 76
    • 79955470208 scopus 로고    scopus 로고
    • Matrix metalloproteinases are associated with increased blood-brain barrier opening in vascular cognitive impairment
    • Candelario-Jalil, E., Thompson, J., Taheri, S., Grossetete, M., Adair, J. C., Edmonds, E., et al. (2011). Matrix metalloproteinases are associated with increased blood-brain barrier opening in vascular cognitive impairment. Stroke, 42, 1345-1350.
    • (2011) Stroke , vol.42 , pp. 1345-1350
    • Candelario-Jalil, E.1    Thompson, J.2    Taheri, S.3    Grossetete, M.4    Adair, J.C.5    Edmonds, E.6
  • 77
    • 77950212895 scopus 로고    scopus 로고
    • Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: Therapeutic implications
    • Candore, G., Bulati, M., Caruso, C., Castiglia, L., Colonna-Romano, G., Di Bona, D., et al. (2010). Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: Therapeutic implications. Rejuvenation Research, 13, 301-313.
    • (2010) Rejuvenation Research , vol.13 , pp. 301-313
    • Candore, G.1    Bulati, M.2    Caruso, C.3    Castiglia, L.4    Colonna-Romano, G.5    Di Bona, D.6
  • 80
    • 0035783530 scopus 로고    scopus 로고
    • Role of nuclear factor kappa B in neuropathological mechanisms
    • Cechetto, D. F. (2001). Role of nuclear factor kappa B in neuropathological mechanisms. Progress in Brain Research, 132, 391-404.
    • (2001) Progress in Brain Research , vol.132 , pp. 391-404
    • Cechetto, D.F.1
  • 81
    • 45049086702 scopus 로고    scopus 로고
    • Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease
    • Cenini, G., Sultana, R., Memo, M., & Butterfield, D. A. (2008a). Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease. Free Radical Biology and Medicine, 45, 81-85.
    • (2008) Free Radical Biology and Medicine , vol.45 , pp. 81-85
    • Cenini, G.1    Sultana, R.2    Memo, M.3    Butterfield, D.A.4
  • 82
    • 44149095262 scopus 로고    scopus 로고
    • Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE,in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease
    • DOI 10.1111/j.1582-4934.2008.00163.x
    • Cenini, G., Sultana, R., Memo, M., & Butterfield, D. A. (2008b). Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease. Journal of Cellular and Molecular Medicine, 12, 987-994. (Pubitemid 351718076)
    • (2008) Journal of Cellular and Molecular Medicine , vol.12 , Issue.3 , pp. 987-994
    • Cenini, G.1    Sultana, R.2    Memo, M.3    Butterfield, D.A.4
  • 83
    • 34447305738 scopus 로고    scopus 로고
    • Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: Potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine
    • DOI 10.1111/j.1471-4159.2007.04589.x
    • Chan, A., & Shea, T. B. (2007). Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine. Journal of Neurochemistry, 102, 753-760. (Pubitemid 47057297)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.3 , pp. 753-760
    • Chan, A.1    Shea, T.B.2
  • 84
  • 85
    • 51849150799 scopus 로고    scopus 로고
    • Lipid peroxidation up-regulates BACE1 expression in vivo: A possible early event of amyloidogenesis in Alzheimer's disease
    • Chen, L., Na, R., Gu, M., Richardson, A., & Ran, Q. (2008). Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease. Journal of Neurochemistry, 107, 197-207.
    • (2008) Journal of Neurochemistry , vol.107 , pp. 197-207
    • Chen, L.1    Na, R.2    Gu, M.3    Richardson, A.4    Ran, Q.5
  • 86
    • 38349143353 scopus 로고    scopus 로고
    • RAGE: A potential target for Abeta-mediated cellular perturbation in Alzheimer's disease
    • Chen, X., Walker, D. G., Schmidt, A. M., Arancio, O., Lue, L. F., & Yan, S. D. (2007). RAGE: A potential target for Abeta-mediated cellular perturbation in Alzheimer's disease. Current Molecular Medicine, 7, 735-742.
    • (2007) Current Molecular Medicine , vol.7 , pp. 735-742
    • Chen, X.1    Walker, D.G.2    Schmidt, A.M.3    Arancio, O.4    Lue, L.F.5    Yan, S.D.6
  • 87
    • 84856459283 scopus 로고    scopus 로고
    • Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
    • Chen, C. H., Zhou, W., Liu, S., Deng, Y., Cai, F., Tone, M., et al. (2011). Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease. The International Journal of Neuropsychopharmacology, 18, 1-14.
    • (2011) The International Journal of Neuropsychopharmacology , vol.18 , pp. 1-14
    • Chen, C.H.1    Zhou, W.2    Liu, S.3    Deng, Y.4    Cai, F.5    Tone, M.6
  • 89
    • 0031976021 scopus 로고    scopus 로고
    • Neurodegeneration induced by MoMuLV-ts1 and increased expression of Fas and TNF-α in the central nervous system
    • DOI 10.1016/S0006-8993(97)00929-3, PII S0006899397009293
    • Choe, W., Stoica, G., Lynn, W., & Wong, P. K. (1998). Neurodegeneration induced by MoMuLV-ts1 and increased expression of Fas and TNF-alpha in the central nervous system. Brain Research, 779, 1-8. (Pubitemid 28039933)
    • (1998) Brain Research , vol.779 , Issue.1-2 , pp. 1-8
    • Choe, W.1    Stoica, G.2    Lynn, W.3    Wong, P.K.Y.4
  • 90
    • 0036889732 scopus 로고    scopus 로고
    • Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-α production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein
    • DOI 10.1016/S0165-5728(02)00349-1, PII S0165572802003491
    • Chong, Y. H., Shin, S. A., Lee, H. J., Kang, J. H., & Suh, Y. H. (2002). Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein. Journal of Neuroimmunology, 133, 160-174. (Pubitemid 35346738)
    • (2002) Journal of Neuroimmunology , vol.133 , Issue.1-2 , pp. 160-174
    • Chong, Y.H.1    Shin, S.A.2    Lee, H.J.3    Kang, J.H.L.4    Suh, Y.-H.5
  • 91
    • 0033954991 scopus 로고    scopus 로고
    • Oxidative stress and Alzheimer disease
    • Christen, Y. (2000). Oxidative stress and Alzheimer disease. American Journal of Clinical Nutrition, 71, 621S-629S. (Pubitemid 30061247)
    • (2000) American Journal of Clinical Nutrition , vol.71 , Issue.2
    • Christen, Y.1
  • 93
    • 57649217285 scopus 로고    scopus 로고
    • The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology
    • Cole, S. L., & Vassar, R. (2008). The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology. The Journal of Biological Chemistry, 283, 29621-29625.
    • (2008) The Journal of Biological Chemistry , vol.283 , pp. 29621-29625
    • Cole, S.L.1    Vassar, R.2
  • 94
    • 71049194220 scopus 로고    scopus 로고
    • Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease
    • Combarros, O., van Duijn, C. M., Hammond, N., Belbin, O., Arias-Vasquez, A., Cortina-Borja, M., et al. (2009). Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease. Journal of Neuroinflammation, 6, 22.
    • (2009) Journal of Neuroinflammation , vol.6 , pp. 22
    • Combarros, O.1    Van Duijn, C.M.2    Hammond, N.3    Belbin, O.4    Arias-Vasquez, A.5    Cortina-Borja, M.6
  • 95
    • 0034651101 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Inhibition of β- amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists
    • Combs, C. K., Johnson, D. E., Karlo, J. C., Cannady, S. B., & Landreth, G. E. (2000). Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. Journal of Neuroscience, 20, 558-567. (Pubitemid 30225558)
    • (2000) Journal of Neuroscience , vol.20 , Issue.2 , pp. 558-567
    • Combs, C.K.1    Johnson, D.E.2    Karlo, J.C.3    Cannady, S.B.4    Landreth, G.E.5
  • 96
    • 0035866060 scopus 로고    scopus 로고
    • β-amyloid stimulation of microglia anti monocytes results in TNFα-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
    • Combs, C. K., Karlo, J. C., Kao, S. C., & Landreth, G. E. (2001). Beta-amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. Journal of Neuroscience, 21, 1179-1188. (Pubitemid 32128763)
    • (2001) Journal of Neuroscience , vol.21 , Issue.4 , pp. 1179-1188
    • Combs, C.K.1    Colleen Karlo, J.2    Kao, S.-C.3    Landreth, G.E.4
  • 97
    • 0343924385 scopus 로고    scopus 로고
    • 2- adrenoceptor binding in the hippocampus following transient global forebrain ischaemia in the rat
    • DOI 10.1016/S0306-4522(97)00321-7, PII S0306452297003217
    • Conway, E. L., Gundlach, A. L., & Craven, J. A. (1998). Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195 binding in relation to imidazoline-I2-receptor and alpha 2-adrenoceptor binding in the hippocampus following transient global forebrain ischaemia in the rat. Neuroscience, 82, 805-817. (Pubitemid 27479619)
    • (1998) Neuroscience , vol.82 , Issue.3 , pp. 805-817
    • Conway, E.L.1    Gundlach, A.L.2    Craven, J.A.3
  • 98
    • 0031958152 scopus 로고    scopus 로고
    • Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease
    • DOI 10.1016/S0197-4580(98)00042-6, PII S0197458098000426
    • Cotman, C. W. (1998). Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease. Neurobiology of Aging, 19, S29-S32. (Pubitemid 28178934)
    • (1998) Neurobiology of Aging , vol.19 , Issue.SUPPL. 1
    • Cotman, C.W.1
  • 100
    • 78649863208 scopus 로고    scopus 로고
    • Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease
    • Cui, J. G., Li, Y. Y., Zhao, Y., Bhattacharjee, S., & Lukiw, W. J. (2010). Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease. The Journal of Biological Chemistry, 285, 38951-38960.
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 38951-38960
    • Cui, J.G.1    Li, Y.Y.2    Zhao, Y.3    Bhattacharjee, S.4    Lukiw, W.J.5
  • 101
    • 34547920377 scopus 로고    scopus 로고
    • Oxidative stress, lipid rafts, and macrophage reprogramming
    • DOI 10.1089/ars.2007.1670
    • Cuschieri, J., & Maier, R. V. (2007). Oxidative stress, lipid rafts, and macrophage reprogramming. Antioxidants & Redox Signaling, 9, 1485-1497. (Pubitemid 47260438)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.9 , pp. 1485-1497
    • Cuschieri, J.1    Maier, R.V.2
  • 102
    • 0030637444 scopus 로고    scopus 로고
    • Les metalloproteinases de la matrice extracellulaire (MMP): Structure et activite
    • Cuvelier, A., Kuntz, C., Sesboue, R., Muir, J. F., & Martin, J. P. (1997). Metalloproteinases in the extracellular matrix: Structure and activity. Revue des Maladies Respiratoires, 14, 1-10. (Pubitemid 27104046)
    • (1997) Revue des Maladies Respiratoires , vol.14 , Issue.1 , pp. 1-10
    • Cuvelier, A.1    Kuntz, C.2    Sesboue, R.3    Muir, J.F.4    Martin, J.P.5
  • 103
    • 65349119198 scopus 로고    scopus 로고
    • Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an 'Alzheimer brain' (review)
    • Dal Pra, I., Chiarini, A., Pacchiana, R., Chakravarthy, B., Whitfield, J. F., & Armato, U. (2008). Emerging concepts of how beta-amyloid proteins and pro-inflammatory cytokines might collaborate to produce an 'Alzheimer brain' (review). Molecular Medicine Reports, 1, 173-178.
    • (2008) Molecular Medicine Reports , vol.1 , pp. 173-178
    • Dal Pra, I.1    Chiarini, A.2    Pacchiana, R.3    Chakravarthy, B.4    Whitfield, J.F.5    Armato, U.6
  • 104
    • 34249672242 scopus 로고    scopus 로고
    • Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
    • DOI 10.1074/jbc.M607483200
    • De Felice, F.G., Velasco, P. T., Lambert, M.P., Viola, K., Fernandez, S. J., Ferreira, S. T., et al. (2007). Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. The Journal of Biological Chemistry, 282, 11590-11601. (Pubitemid 47100810)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.15 , pp. 11590-11601
    • De Felice, F.G.1    Velasco, P.T.2    Lambert, M.P.3    Viola, K.4    Fernandez, S.J.5    Ferreira, S.T.6    Klein, W.L.7
  • 105
    • 0033903441 scopus 로고    scopus 로고
    • Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease
    • de la Monte, S. M., Luong, T., Neely, T. R., Robinson, D., & Wands, J. R. (2000). Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease. Laboratory Investigation, 80, 1323-1335. (Pubitemid 30637072)
    • (2000) Laboratory Investigation , vol.80 , Issue.8 , pp. 1323-1335
    • De La Monte, S.M.1    Luong, T.2    Neely, T.R.3    Robinson, D.4    Wands, J.R.5
  • 106
    • 0027314240 scopus 로고
    • Can disturbed brain microcirculation cause Alzheimer's disease?
    • de la Torre, J. C., & Mussivand, T. (1993). Can disturbed brain microcirculation cause Alzheimer's disease? Neurological Research, 15, 146-153. (Pubitemid 23166998)
    • (1993) Neurological Research , vol.15 , Issue.3 , pp. 146-153
    • De La Torre, J.C.1    Mussivand, T.2
  • 107
    • 65649105035 scopus 로고    scopus 로고
    • Clearance of amyloid-beta peptide across the blood-brain barrier: Implication for therapies in Alzheimer's disease
    • Deane, R., Bell, R. D., Sagare, A., & Zlokovic, B. V. (2009). Clearance of amyloid-beta peptide across the blood-brain barrier: Implication for therapies in Alzheimer's disease. CNS & Neurological Disorders Drug Targets, 8, 16-30.
    • (2009) CNS & Neurological Disorders Drug Targets , vol.8 , pp. 16-30
    • Deane, R.1    Bell, R.D.2    Sagare, A.3    Zlokovic, B.V.4
  • 109
    • 57449084208 scopus 로고    scopus 로고
    • ApoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain
    • Deane, R., Sagare, A., Hamm, K., Parisi, M., Lane, S., Finn, M. B., et al. (2008a). apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. Journal of Clinical Investigation, 118, 4002-4013.
    • (2008) Journal of Clinical Investigation , vol.118 , pp. 4002-4013
    • Deane, R.1    Sagare, A.2    Hamm, K.3    Parisi, M.4    Lane, S.5    Finn, M.B.6
  • 110
    • 48949117577 scopus 로고    scopus 로고
    • The role of the cell surface LRP and soluble LRP in blood-brain barrier Aβ clearance in Alzheimer's disease
    • DOI 10.2174/138161208784705487
    • Deane, R., Sagare, A., & Zlokovic, B. V. (2008b). The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease. Current Pharmaceutical Design, 14, 1601-1605. (Pubitemid 352002987)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.16 , pp. 1601-1605
    • Dearie, R.1    Sagare, A.2    Zlokovic, B.V.3
  • 111
    • 7644225312 scopus 로고    scopus 로고
    • RAGE (Yin) versus LRP (Yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier
    • DOI 10.1161/01.STR.0000143452.85382.d1
    • Deane, R., Wu, Z., & Zlokovic, B. V. (2004). RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier. Stroke, 35, 2628-2631. (Pubitemid 39458354)
    • (2004) Stroke , vol.35 , Issue.SUPPL. 1 , pp. 2628-2631
    • Deane, R.1    Wu, Z.2    Zlokovic, B.V.3
  • 113
    • 0028946146 scopus 로고
    • Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and beta-amyloid production in cultures
    • Del Bo, R., Angeretti, N., Lucca, E., De Simoni, M. G., & Forloni, G. (1995). Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and beta-amyloid production in cultures. Neuroscience Letters, 188, 70-74.
    • (1995) Neuroscience Letters , vol.188 , pp. 70-74
    • Del Bo, R.1    Angeretti, N.2    Lucca, E.3    De Simoni, M.G.4    Forloni, G.5
  • 114
    • 1642570212 scopus 로고    scopus 로고
    • Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons
    • DOI 10.1073/pnas.0307349101
    • Del Villar, K., & Miller, C. A. (2004). Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America, 101, 4210-4215. (Pubitemid 38405908)
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , Issue.12 , pp. 4210-4215
    • Del Villar, K.1    Miller, C.A.2
  • 115
    • 33747417084 scopus 로고    scopus 로고
    • Integrin-matrix interactions in the cerebral microvasculature
    • DOI 10.1161/01.ATV.0000232525.65682.a2, PII 0004360520060900000007
    • del Zoppo, G. J., & Milner, R. (2006). Integrin-matrix interactions in the cerebral microvasculature. Arteriosclerosis, Thrombosis, and Vascular Biology, 26, 1966-1975. (Pubitemid 44253776)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.9 , pp. 1966-1975
    • Del Zoppo, G.J.1    Milner, R.2
  • 117
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson, D. W., Lee, S. C., Mattiace, L. A., Yen, S. H., & Brosnan, C. (1993). Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia, 7, 75-83.
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4    Brosnan, C.5
  • 118
    • 0033874108 scopus 로고    scopus 로고
    • Proinflammatory cytokines
    • Dinarello, C. A. (2000). Proinflammatory cytokines. Chest, 118, 503-508. (Pubitemid 30637822)
    • (2000) Chest , vol.118 , Issue.2 , pp. 503-508
    • Dinarello, C.A.1
  • 120
    • 41949101345 scopus 로고    scopus 로고
    • Apolipoprotein E, amyloid-β, and blood-brain barrier permeability in Alzheimer disease
    • DOI 10.1097/NEN.0b013e31816a0dc8, PII 0000507220080400000001
    • Donahue, J. E., & Johanson, C. E. (2008). Apolipoprotein E, amyloid-beta, and blood-brain barrier permeability in Alzheimer disease. Journal of Neuropathology and Experimental Neurology, 67, 261-270. (Pubitemid 351507482)
    • (2008) Journal of Neuropathology and Experimental Neurology , vol.67 , Issue.4 , pp. 261-270
    • Donahue, J.E.1    Johanson, C.E.2
  • 122
    • 58649099395 scopus 로고    scopus 로고
    • Ageassociated oxidative damage to the p62 promoter: Implications for Alzheimer disease
    • Du, Y., Wooten, M. C., Gearing, M., & Wooten, M. W. (2009). Ageassociated oxidative damage to the p62 promoter: Implications for Alzheimer disease. Free Radical Biology and Medicine, 46, 492-501.
    • (2009) Free Radical Biology and Medicine , vol.46 , pp. 492-501
    • Du, Y.1    Wooten, M.C.2    Gearing, M.3    Wooten, M.W.4
  • 123
    • 80051665640 scopus 로고    scopus 로고
    • Neuroprotective strategies involving ROS in Alzheimer disease
    • Dumont, M., & Beal, M. F. (2010). Neuroprotective strategies involving ROS in Alzheimer disease. Free Radical Biology & Medicine, 51, 1014-1026.
    • (2010) Free Radical Biology & Medicine , vol.51 , pp. 1014-1026
    • Dumont, M.1    Beal, M.F.2
  • 124
    • 67349143998 scopus 로고    scopus 로고
    • Classification and basic pathology of Alzheimer disease
    • Duyckaerts, C., Delatour, B., & Potier, M. C. (2009). Classification and basic pathology of Alzheimer disease. Acta Neuropathologica, 118, 5-36.
    • (2009) Acta Neuropathologica , vol.118 , pp. 5-36
    • Duyckaerts, C.1    Delatour, B.2    Potier, M.C.3
  • 126
    • 79951882202 scopus 로고    scopus 로고
    • Zebrafish model of the blood-brain barrier: Morphological and permeability studies
    • Eliceiri, B. P., Gonzalez, A. M., & Baird, A. (2011). Zebrafish model of the blood-brain barrier: Morphological and permeability studies. Methods in Molecular Biology, 686, 371-378.
    • (2011) Methods in Molecular Biology , vol.686 , pp. 371-378
    • Eliceiri, B.P.1    Gonzalez, A.M.2    Baird, A.3
  • 127
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A Review of Programmed Cell Death
    • DOI 10.1080/01926230701320337, PII 779478428
    • Elmore, S. (2007). Apoptosis: A review of programmed cell death. Toxicologic Pathology, 35, 495-516. (Pubitemid 46911891)
    • (2007) Toxicologic Pathology , vol.35 , Issue.4 , pp. 495-516
    • Elmore, S.1
  • 128
    • 77951647591 scopus 로고    scopus 로고
    • RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
    • Fang, F., Lue, L. F., Yan, S., Xu, H., Luddy, J. S., Chen, D., et al. (2010). RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease. FASEB J, 24, 1043-1055.
    • (2010) FASEB J , vol.24 , pp. 1043-1055
    • Fang, F.1    Lue, L.F.2    Yan, S.3    Xu, H.4    Luddy, J.S.5    Chen, D.6
  • 130
  • 132
    • 71849103796 scopus 로고    scopus 로고
    • Biomarkers of inflammation and amyloid-beta phagocytosis in patients at risk of Alzheimer disease
    • Fiala, M., & Veerhuis, R. (2010). Biomarkers of inflammation and amyloid-beta phagocytosis in patients at risk of Alzheimer disease. Experimental Gerontology, 45, 57-63.
    • (2010) Experimental Gerontology , vol.45 , pp. 57-63
    • Fiala, M.1    Veerhuis, R.2
  • 134
  • 135
    • 78650462753 scopus 로고    scopus 로고
    • Alzheimer's disease: A general introduction and pathomechanism
    • Finder, V. H. (2010). Alzheimer's disease: A general introduction and pathomechanism. Journal of Alzheimer's Disease, 22(Suppl 3), 5-19.
    • (2010) Journal of Alzheimer's Disease , vol.22 , Issue.SUPPL. 3 , pp. 5-19
    • Finder, V.H.1
  • 137
    • 3242712276 scopus 로고    scopus 로고
    • Redox signaling: Thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers
    • DOI 10.1152/ajpcell.00516.2003
    • Forman, H. J., Fukuto, J. M., & Torres, M. (2004). Redox signaling: Thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers. American Journal of Physiology, 287, C246-C256. (Pubitemid 38955213)
    • (2004) American Journal of Physiology - Cell Physiology , vol.287 , Issue.2
    • Forman, H.J.1    Fukuto, J.M.2    Torres, M.3
  • 138
    • 0028171110 scopus 로고
    • Non-fibrillar beta-amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease
    • Frackowiak, J., Zoltowska, A., & Wisniewski, H. M. (1994). Non-fibrillar beta-amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease. Journal of Neuropathology and Experimental Neurology, 53, 637-645.
    • (1994) Journal of Neuropathology and Experimental Neurology , vol.53 , pp. 637-645
    • Frackowiak, J.1    Zoltowska, A.2    Wisniewski, H.M.3
  • 139
    • 33646408493 scopus 로고    scopus 로고
    • Regulatory dendritic cells act as regulators of acute lethal systemic inflammatory response
    • Fujita, S., Seino, K., Sato, K., Sato, Y., Eizumi, K., Yamashita, N., et al. (2006). Regulatory dendritic cells act as regulators of acute lethal systemic inflammatory response. Blood, 107, 3656-3664.
    • (2006) Blood , vol.107 , pp. 3656-3664
    • Fujita, S.1    Seino, K.2    Sato, K.3    Sato, Y.4    Eizumi, K.5    Yamashita, N.6
  • 140
    • 77955281765 scopus 로고    scopus 로고
    • Activated astroglia during chronic inflammation in Alzheimer's disease - Do they neglect their neurosupportive roles?
    • Fuller, S., Steele, M., & Munch, G. (2010). Activated astroglia during chronic inflammation in Alzheimer's disease - do they neglect their neurosupportive roles? Mutation Research, 690, 40-49.
    • (2010) Mutation Research , vol.690 , pp. 40-49
    • Fuller, S.1    Steele, M.2    Munch, G.3
  • 141
    • 77951689435 scopus 로고    scopus 로고
    • Biomarkers of oxidative damage and inflammation in Alzheimer's disease
    • Galasko, D., & Montine, T. J. (2010). Biomarkers of oxidative damage and inflammation in Alzheimer's disease. Biomarkers in Medicine, 4, 27-36.
    • (2010) Biomarkers in Medicine , vol.4 , pp. 27-36
    • Galasko, D.1    Montine, T.J.2
  • 143
    • 0041304626 scopus 로고    scopus 로고
    • El daño nuclear neuronal se correlaciona con la detección in situ de los factores de transcripción c-Jun, factor nuclear κb, p53 y Par-4 en la enfermedad de Alzheimer
    • Garcia-Ospina, G. P., Jimenez-Del Rio, M., Lopera, F., & Velez-Pardo, C. (2003). Neuronal DNA damage correlates with a positive detection of c-Jun, nuclear factor kB, p53 and Par-4 transcription factors in Alzheimer's disease. Revista de Neurologia, 36, 1004-1010. (Pubitemid 36899381)
    • (2003) Revista de Neurologia , vol.36 , Issue.11 , pp. 1004-1010
    • Garcia-Ospina, G.P.1    Jimenez-Del Rio, M.2    Lopera, F.3    Velez-Pardo, C.4
  • 144
    • 1842483365 scopus 로고    scopus 로고
    • Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility
    • Garrido, N., Meseguer, M., Simon, C., Pellicer, A., & Remohi, J. (2004). Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian Journal of Andrology, 6, 59-65. (Pubitemid 38418340)
    • (2004) Asian Journal of Andrology , vol.6 , Issue.1 , pp. 59-65
    • Garrido, N.1    Meseguer, M.2    Simon, C.3    Pellicer, A.4    Remohi, J.5
  • 145
    • 0035194622 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia
    • Gasche, Y., Copin, J. C., Sugawara, T., Fujimura, M., & Chan, P. H. (2001). Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism, 21, 1393-1400. (Pubitemid 33120943)
    • (2001) Journal of Cerebral Blood Flow and Metabolism , vol.21 , Issue.12 , pp. 1393-1400
    • Gasche, Y.1    Copin, J.-C.2    Sugawara, T.3    Fujimura, M.4    Chan, P.H.5
  • 146
    • 0037305211 scopus 로고    scopus 로고
    • Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y
    • Gasic-Milenkovic, J., Loske, C., & Munch, G. (2003). Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y. Journal of Alzheimer's Disease, 5, 25-30. (Pubitemid 36422848)
    • (2003) Journal of Alzheimer's Disease , vol.5 , Issue.1 , pp. 25-30
    • Gasic-Milenkovic, J.1    Loske, C.2    Munch, G.3
  • 147
    • 0036959504 scopus 로고    scopus 로고
    • Regulation of promoter activity of the APP gene by cytokines and growth factors: Implications in Alzheimer's disease
    • Ge, Y. W., & Lahiri, D. K. (2002). Regulation of promoter activity of the APP gene by cytokines and growth factors: Implications in Alzheimer's disease. Annals of the New York Academy of Sciences, 973, 463-467. (Pubitemid 36125054)
    • (2002) Annals of the New York Academy of Sciences , vol.973 , pp. 463-467
    • Ge, Y.-W.1    Lahiri, D.K.2
  • 148
    • 67049134478 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer disease
    • Gella, A., & Durany, N. (2009). Oxidative stress in Alzheimer disease. Cell Adhesion & Migration, 3, 88-93.
    • (2009) Cell Adhesion & Migration , vol.3 , pp. 88-93
    • Gella, A.1    Durany, N.2
  • 150
    • 33749161414 scopus 로고    scopus 로고
    • Deposition of iron and β-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets
    • DOI 10.1111/j.1471-4159.2006.04079.x
    • Ghribi, O., Golovko, M. Y., Larsen, B., Schrag, M., & Murphy, E. J. (2006). Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets. Journal of Neurochemistry, 99, 438-449. (Pubitemid 44477201)
    • (2006) Journal of Neurochemistry , vol.99 , Issue.2 , pp. 438-449
    • Ghribi, O.1    Golovko, M.Y.2    Larsen, B.3    Schrag, M.4    Murphy, E.J.5
  • 151
    • 0030009314 scopus 로고    scopus 로고
    • BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells
    • Giardino, I., Edelstein, D., & Brownlee, M. (1996). BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells. Journal of Clinical Investigation, 97, 1422-1428. (Pubitemid 26097031)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.6 , pp. 1422-1428
    • Giardino, I.1    Edelstein, D.2    Brownlee, M.3
  • 152
    • 0033382224 scopus 로고    scopus 로고
    • Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits
    • Gibson, G. E., Park, L. C., Zhang, H., Sorbi, S., & Calingasan, N. Y. (1999). Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits. Annals of the New York Academy of Sciences, 893, 79-94. (Pubitemid 30038069)
    • (1999) Annals of the New York Academy of Sciences , vol.893 , pp. 79-94
    • Gibson, G.E.1    Park, L.C.H.2    Zhang, H.3    Sorbi, S.4    Calingasan, N.Y.5
  • 153
    • 0034986361 scopus 로고    scopus 로고
    • Oxidative stress induced-neurodegenerative diseases: The need for antioxidants that penetrate the blood brain barrier
    • DOI 10.1016/S0028-3908(01)00019-3, PII S0028390801000193
    • Gilgun-Sherki, Y., Melamed, E., & Offen, D. (2001). Oxidative stress induced-neurodegenerative diseases: The need for antioxidants that penetrate the blood brain barrier. Neuropharmacology, 40, 959-975. (Pubitemid 32530602)
    • (2001) Neuropharmacology , vol.40 , Issue.8 , pp. 959-975
    • Gilgun-Sherki, Y.1    Melamed, E.2    Offen, D.3
  • 154
    • 0141673405 scopus 로고    scopus 로고
    • Antioxidant treatment in Alzheimer's disease: Current state
    • DOI 10.1385/JMN:21:1:1
    • Gilgun-Sherki, Y., Melamed, E., & Offen, D. (2003). Antioxidant treatment in Alzheimer's disease: Current state. Journal of Molecular Neuroscience, 21, 1-11. (Pubitemid 37204866)
    • (2003) Journal of Molecular Neuroscience , vol.21 , Issue.1 , pp. 1-11
    • Gilgun-Sherki, Y.1    Melamed, E.2    Offen, D.3
  • 155
    • 0029665123 scopus 로고    scopus 로고
    • Apoptosis and metastasis: A superior resistance of metastatic cancer cells to programmed cell death
    • DOI 10.1016/0304-3835(96)04112-2
    • Glinsky, G. V., & Glinsky, V. V. (1996). Apoptosis and metastasis: A superior resistance of metastatic cancer cells to programmed cell death. Cancer Letters, 101, 43-51. (Pubitemid 26060191)
    • (1996) Cancer Letters , vol.101 , Issue.1 , pp. 43-51
    • Glinsky, G.V.1    Glinsky, V.V.2
  • 156
    • 0036732407 scopus 로고    scopus 로고
    • Inflammation takes on Alzheimer disease
    • DOI 10.1038/nm0902-936
    • Golde, T. E. (2002). Inflammation takes on Alzheimer disease. Nature Medicine, 8, 936-938. (Pubitemid 35033689)
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 936-938
    • Golde, T.E.1
  • 158
    • 33644869901 scopus 로고    scopus 로고
    • Inflammation and neurodegenerative diseases
    • Griffin, W. S. (2006). Inflammation and neurodegenerative diseases. American Journal of Clinical Nutrition, 83, 470S-474S. (Pubitemid 44713221)
    • (2006) American Journal of Clinical Nutrition , vol.83 , Issue.2
    • Griffin, W.S.T.1
  • 159
    • 0033863718 scopus 로고    scopus 로고
    • Aged garlic extract suppresses lipid peroxidation induced by β-amyloid in PC12 cells [1]
    • Griffin, B., Selassie, M., & Gwebu, E. T. (2000). Aged garlic extract suppresses lipid peroxidation induced by beta-amyloid in PC12 cells. In Vitro Cellular & Developmental Biology. Animal, 36, 279-280. (Pubitemid 30619590)
    • (2000) Vitro Cellular and Developmental Biology - Animal , vol.36 , Issue.5 , pp. 279-280
    • Griffin, B.1    Selassie, M.2    Gwebu, E.T.3
  • 160
    • 0028167986 scopus 로고
    • Microglial interleukin-1 alpha expression in human head injury: Correlations with neuronal and neuritic beta-amyloid precursor protein expression
    • Griffin, W. S., Sheng, J. G., Gentleman, S. M., Graham, D. I., Mrak, R. E., & Roberts, G. W. (1994). Microglial interleukin-1 alpha expression in human head injury: Correlations with neuronal and neuritic beta-amyloid precursor protein expression. Neuroscience Letters, 176, 133-136.
    • (1994) Neuroscience Letters , vol.176 , pp. 133-136
    • Griffin, W.S.1    Sheng, J.G.2    Gentleman, S.M.3    Graham, D.I.4    Mrak, R.E.5    Roberts, G.W.6
  • 161
  • 162
    • 0036084541 scopus 로고    scopus 로고
    • Antioxidant strategies for Alzheimer's disease
    • DOI 10.1079/PNS2002146
    • Grundman, M., & Delaney, P. (2002). Antioxidant strategies for Alzheimer's disease. Proceedings of the Nutrition Society, 61, 191-202. (Pubitemid 34665793)
    • (2002) Proceedings of the Nutrition Society , vol.61 , Issue.2 , pp. 191-202
    • Grundman, M.1    Delaney, P.2
  • 163
    • 80053121818 scopus 로고    scopus 로고
    • Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability
    • Gu, Y., Dee, C. M., & Shen, J. (2011a). Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability. Frontiers in Bioscience (Scholar Edition), 3, 1216-1231.
    • (2011) Frontiers in Bioscience (Scholar Edition) , vol.3 , pp. 1216-1231
    • Gu, Y.1    Dee, C.M.2    Shen, J.3
  • 165
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • DOI 10.1038/4789
    • Guo, Q., Fu, W., Sopher, B. L., Miller, M. W., Ware, C. B., Martin, G. M., et al. (1999). Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nature Medicine, 5, 101-106. (Pubitemid 29051006)
    • (1999) Nature Medicine , vol.5 , Issue.1 , pp. 101-106
    • Guo, Q.1    Fu, W.2    Sopher, B.L.3    Miller, M.W.4    Ware, C.B.5    Martin, G.M.6    Mattson, M.P.7
  • 166
    • 33745862737 scopus 로고    scopus 로고
    • An assessment of the role of reactive oxygen species and redox signaling in norepinephrineinduced apoptosis and hypertrophy of H9c2 cardiac myoblasts
    • Gupta, M. K., Neelakantan, T. V., Sanghamitra, M., Tyagi, R. K., Dinda, A., Maulik, S., et al. (2006). An assessment of the role of reactive oxygen species and redox signaling in norepinephrineinduced apoptosis and hypertrophy of H9c2 cardiac myoblasts. Antioxidants & Redox Signaling, 8, 1081-1093.
    • (2006) Antioxidants & Redox Signaling , vol.8 , pp. 1081-1093
    • Gupta, M.K.1    Neelakantan, T.V.2    Sanghamitra, M.3    Tyagi, R.K.4    Dinda, A.5    Maulik, S.6
  • 167
    • 33750475625 scopus 로고    scopus 로고
    • Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells
    • DOI 10.1161/01.RES.0000248212.86638.e9, PII 0000301220061027000005
    • Gutierrez, J., Ballinger, S. W., Darley-Usmar, V. M., & Landar, A. (2006). Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells. Circulation Research, 99, 924-932. (Pubitemid 44657795)
    • (2006) Circulation Research , vol.99 , Issue.9 , pp. 924-932
    • Gutierrez, J.1    Ballinger, S.W.2    Darley-Usmar, V.M.3    Landar, A.4
  • 168
    • 0036829062 scopus 로고    scopus 로고
    • Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors
    • DOI 10.1016/S0898-6568(02)00053-0, PII S0898656802000530
    • Haddad, J. J. (2002). Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors. Cellular Signalling, 14, 879-897. (Pubitemid 35247561)
    • (2002) Cellular Signalling , vol.14 , Issue.11 , pp. 879-897
    • Haddad, J.J.1
  • 169
    • 0037318947 scopus 로고    scopus 로고
    • Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: Role for hypoxia-inducible factor-1α
    • DOI 10.1186/cc1840
    • Haddad, J. J. (2003). Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: Role for hypoxia-inducible factor-1alpha. Critical Care, 7, 47-54. (Pubitemid 36204269)
    • (2003) Critical Care , vol.7 , Issue.1 , pp. 47-54
    • Haddad, J.J.1
  • 170
    • 34047114464 scopus 로고    scopus 로고
    • Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction
    • DOI 10.1111/j.1471-4159.2006.04393.x
    • Haorah, J., Ramirez, S. H., Schall, K., Smith, D., Pandya, R., & Persidsky, Y. (2007). Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction. Journal of Neurochemistry, 101, 566-576. (Pubitemid 46525283)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.2 , pp. 566-576
    • Haorah, J.1    Ramirez, S.H.2    Schall, K.3    Smith, D.4    Pandya, R.5    Persidsky, Y.6
  • 171
    • 33845915580 scopus 로고    scopus 로고
    • Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: Contribution of hyperglycaemia and matrix metalloproteinases
    • DOI 10.1007/s00125-006-0485-z
    • Hawkins, B. T., Lundeen, T. F., Norwood, K. M., Brooks, H. L., & Egleton, R. D. (2007). Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: Contribution of hyperglycaemia and matrix metalloproteinases. Diabetologia, 50, 202-211. (Pubitemid 46035869)
    • (2007) Diabetologia , vol.50 , Issue.1 , pp. 202-211
    • Hawkins, B.T.1    Lundeen, T.F.2    Norwood, K.M.3    Brooks, H.L.4    Egleton, R.D.5
  • 172
    • 33644872474 scopus 로고    scopus 로고
    • Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells
    • DOI 10.1074/jbc.M507367200
    • Heimlich, G., & Cidlowski, J. A. (2006). Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells. The Journal of Biological Chemistry, 281, 2232-2241. (Pubitemid 43845814)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.4 , pp. 2232-2241
    • Heimlich, G.1    Cidlowski, J.A.2
  • 173
    • 56149092961 scopus 로고    scopus 로고
    • Survival in Alzheimer disease: A multiethnic, population-based study of incident cases
    • Helzner, E. P., Scarmeas, N., Cosentino, S., Tang, M. X., Schupf, N., & Stern, Y. (2008). Survival in Alzheimer disease: A multiethnic, population-based study of incident cases. Neurology, 71, 1489-1495.
    • (2008) Neurology , vol.71 , pp. 1489-1495
    • Helzner, E.P.1    Scarmeas, N.2    Cosentino, S.3    Tang, M.X.4    Schupf, N.5    Stern, Y.6
  • 174
    • 33847613885 scopus 로고    scopus 로고
    • Inflammatory processes in Alzheimer's disease
    • DOI 10.1016/j.jneuroim.2006.11.017, PII S016557280600470X, Inflammation, Neurodegeneration and Neuroprotection in the Central Nervous System
    • Heneka, M. T., & O'Banion, M. K. (2007). Inflammatory processes in Alzheimer's disease. Journal of Neuroimmunology, 184, 69-91. (Pubitemid 46365992)
    • (2007) Journal of Neuroimmunology , vol.184 , Issue.1-2 , pp. 69-91
    • Heneka, M.T.1    O'Banion, M.K.2
  • 176
    • 33947640544 scopus 로고    scopus 로고
    • On the relation of oxidative stress to neuroinflammation: Lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
    • Hensley, K., Mhatre, M., Mou, S., Pye, Q. N., Stewart, C., West, M., et al. (2006). On the relation of oxidative stress to neuroinflammation: Lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. Antioxidants & Redox Signaling, 8, 2075-2087. (Pubitemid 46489632)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.11-12 , pp. 2075-2087
    • Hensley, K.1    Mhatre, M.2    Mou, S.3    Pye, Q.N.4    Stewart, C.5    West, M.6    Williamson, K.S.7
  • 177
    • 0034807447 scopus 로고    scopus 로고
    • Protective effect of 4′,5-dihydroxy-3′,6,7-trimethoxyflavone from Artemisia asiatica against Aβ-induced oxidative stress in PC12 cells
    • Heo, H. J., Cho, H. Y., Hong, B., Kim, H. K., Kim, E. K., Kim, B. G., et al. (2001). Protective effect of 4',5-dihydroxy-3',6,7-trimethoxyflavone from Artemisia asiatica against Abeta-induced oxidative stress in PC12 cells. Amyloid, 8, 194-201. (Pubitemid 32911605)
    • (2001) Amyloid , vol.8 , Issue.3 , pp. 194-201
    • Heo, H.-J.1    Cho, H.-Y.2    Hong, B.3    Kim, H.-K.4    Kim, E.-K.5    Kim, B.-G.6    Shin, D.-H.7
  • 178
    • 37049014488 scopus 로고    scopus 로고
    • Plasma aminothiol compounds, but not serum tumor necrosis factor receptor II and soluble receptor for advanced glycation end products, are related to the cognitive impairment in Alzheimer's disease and mild cognitive impairment patients
    • DOI 10.1159/000110641
    • Hernanz, A., De la Fuente, M., Navarro, M., & Frank, A. (2007). Plasma aminothiol compounds, but not serum tumor necrosis factor receptor II and soluble receptor for advanced glycation end products, are related to the cognitive impairment in Alzheimer's disease and mild cognitive impairment patients. Neuroimmunomodulation, 14, 163-167. (Pubitemid 350249112)
    • (2007) NeuroImmunoModulation , vol.14 , Issue.3-4 , pp. 163-167
    • Hernanz, A.1    De La Fuente, M.2    Navarro, M.3    Frank, A.4
  • 179
    • 71549171964 scopus 로고    scopus 로고
    • Reduction of cerebral oxidative stress following environmental enrichment in mice with Alzheimerlike pathology
    • Herring, A., Blome, M., Ambree, O., Sachser, N., Paulus, W., & Keyvani, K. (2010). Reduction of cerebral oxidative stress following environmental enrichment in mice with Alzheimerlike pathology. Brain Pathology, 20, 166-175.
    • (2010) Brain Pathology , vol.20 , pp. 166-175
    • Herring, A.1    Blome, M.2    Ambree, O.3    Sachser, N.4    Paulus, W.5    Keyvani, K.6
  • 181
    • 67349230450 scopus 로고    scopus 로고
    • Downregulation of LRP1 [correction of LPR1] at the blood-brain barrier in streptozotocin-induced diabetic mice
    • Hong, H., Liu, L. P., Liao, J. M., Wang, T. S., Ye, F. Y., Wu, J., et al. (2009). Downregulation of LRP1 [correction of LPR1] at the blood-brain barrier in streptozotocin-induced diabetic mice. Neuropharmacology, 56, 1054-1059.
    • (2009) Neuropharmacology , vol.56 , pp. 1054-1059
    • Hong, H.1    Liu, L.P.2    Liao, J.M.3    Wang, T.S.4    Ye, F.Y.5    Wu, J.6
  • 182
    • 77957321489 scopus 로고    scopus 로고
    • Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease
    • Horstmann, S., Budig, L., Gardner, H., Koziol, J., Deuschle, M., Schilling, C., et al. (2010). Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with Alzheimer's disease. International Psychogeriatrics, 22, 966-972.
    • (2010) International Psychogeriatrics , vol.22 , pp. 966-972
    • Horstmann, S.1    Budig, L.2    Gardner, H.3    Koziol, J.4    Deuschle, M.5    Schilling, C.6
  • 183
    • 1842504323 scopus 로고    scopus 로고
    • Redox-active metals, oxidative stress, and Alzheimer's disease pathology
    • DOI 10.1196/annals.1306.012
    • Huang, X., Moir, R. D., Tanzi, R. E., Bush, A. I., & Rogers, J. T. (2004). Redox-active metals, oxidative stress, and Alzheimer's disease pathology. Annals of the New York Academy of Sciences, 1012, 153-163. (Pubitemid 38453522)
    • (2004) Annals of the New York Academy of Sciences , vol.1012 , pp. 153-163
    • Huang, X.1    Moir, R.D.2    Tanzi, R.E.3    Bush, A.I.4    Rogers, J.T.5
  • 187
    • 67849099661 scopus 로고    scopus 로고
    • Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition
    • Jaeger, L. B., Dohgu, S., Hwang, M. C., Farr, S. A., Murphy, M. P., Fleegal-DeMotta, M. A., et al. (2009a). Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition. Journal of Alzheimer's Disease, 17, 553-570.
    • (2009) Journal of Alzheimer's Disease , vol.17 , pp. 553-570
    • Jaeger, L.B.1    Dohgu, S.2    Hwang, M.C.3    Farr, S.A.4    Murphy, M.P.5    Fleegal-DeMotta, M.A.6
  • 188
    • 63249094657 scopus 로고    scopus 로고
    • Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: A mechanism for inflammation in the progression of Alzheimer's disease
    • Jaeger, L. B., Dohgu, S., Sultana, R., Lynch, J. L., Owen, J. B., Erickson, M. A., et al. (2009b). Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: A mechanism for inflammation in the progression of Alzheimer's disease. Brain, Behavior, and Immunity, 23, 507-517.
    • (2009) Brain, Behavior, and Immunity , vol.23 , pp. 507-517
    • Jaeger, L.B.1    Dohgu, S.2    Sultana, R.3    Lynch, J.L.4    Owen, J.B.5    Erickson, M.A.6
  • 189
    • 53549086409 scopus 로고    scopus 로고
    • Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis
    • Jeynes, B., & Provias, J. (2008). Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis. Current Alzheimer Research, 5, 432-437.
    • (2008) Current Alzheimer Research , vol.5 , pp. 432-437
    • Jeynes, B.1    Provias, J.2
  • 190
    • 0035082722 scopus 로고    scopus 로고
    • Amyloid β40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice
    • Ji, Y., Permanne, B., Sigurdsson, E. M., Holtzman, D. M., & Wisniewski, T. (2001). Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice. Journal of Alzheimer's Disease, 3, 23-30. (Pubitemid 32238247)
    • (2001) Journal of Alzheimer's Disease , vol.3 , Issue.1 , pp. 23-30
    • Ji, Y.1    Permanne, B.2    Sigurdsson, E.M.3    Holtzman, D.M.4    Wisniewski, T.5
  • 191
    • 19544371396 scopus 로고    scopus 로고
    • Matrix metalloproteinases and free radicals in cerebral ischemia
    • DOI 10.1016/j.freeradbiomed.2005.03.033, PII S0891584905001905
    • Jian Liu, K., & Rosenberg, G. A. (2005). Matrix metalloproteinases and free radicals in cerebral ischemia. Free Radical Biology and Medicine, 39, 71-80. (Pubitemid 40733117)
    • (2005) Free Radical Biology and Medicine , vol.39 , Issue.1 , pp. 71-80
    • Liu, K.J.1    Rosenberg, G.A.2
  • 192
    • 1642407666 scopus 로고    scopus 로고
    • Interleukin-1β Induces A Reactive Astroglial Phenotype Via Deactivation of the Rho GTPase-Rock Axis
    • DOI 10.1523/JNEUROSCI.4789-03.2004
    • John, G. R., Chen, L., Rivieccio, M. A., Melendez-Vasquez, C. V., Hartley, A., & Brosnan, C. F. (2004). Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. Journal of Neuroscience, 24, 2837-2845. (Pubitemid 38380962)
    • (2004) Journal of Neuroscience , vol.24 , Issue.11 , pp. 2837-2845
    • John, G.R.1    Chen, L.2    Rivieccio, M.A.3    Melendez-Vasquez, C.V.4    Hartley, A.5    Brosnan, C.F.6
  • 195
    • 15244360536 scopus 로고    scopus 로고
    • 2 or 2,2-azobis-(2-amidinopropane) dihydrochloride by the glutathione mimetic tricyclodecan-9-yl-xanthogenate
    • DOI 10.1016/j.freeradbiomed.2004.12.027
    • 2 or 2,2-azobis-(2-amidinopropane) dihydrochloride by the glutathione mimetic tricyclodecan-9-ylxanthogenate. Free Radical Biology and Medicine, 38, 1023-1031. (Pubitemid 40386548)
    • (2005) Free Radical Biology and Medicine , vol.38 , Issue.8 , pp. 1023-1031
    • Joshi, G.1    Sultana, R.2    Perluigi, M.3    Butterfield, D.A.4
  • 196
    • 0030663141 scopus 로고    scopus 로고
    • Cerebrovascular degeneration is related to amyloid-β protein deposition in Alzheimer's disease
    • DOI 10.1111/j.1749-6632.1997.tb48478.x
    • Kalaria, R. N. (1997). Cerebrovascular degeneration is related to amyloid-beta protein deposition in Alzheimer's disease. Annals of the New York Academy of Sciences, 826, 263-271. (Pubitemid 27478048)
    • (1997) Annals of the New York Academy of Sciences , vol.826 , pp. 263-271
    • Kalaria, R.N.1
  • 197
    • 0036130159 scopus 로고    scopus 로고
    • Small vessel disease and alzheimer's dementia: Pathological considerations
    • DOI 10.1159/000049150
    • Kalaria, R. N. (2002). Small vessel disease and Alzheimer's dementia: Pathological considerations. Cerebrovascular Diseases, 13(Suppl 2), 48-52. (Pubitemid 34233909)
    • (2002) Cerebrovascular Diseases , vol.13 , Issue.SUPPL. 2 , pp. 48-52
    • Kalaria, R.N.1
  • 198
    • 0024419325 scopus 로고
    • Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease
    • Kalaria, R. N., & Harik, S. I. (1989). Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease. Journal of Neurochemistry, 53, 1083-1088. (Pubitemid 19238473)
    • (1989) Journal of Neurochemistry , vol.53 , Issue.4 , pp. 1083-1088
    • Kalaria, R.N.1    Harik, S.I.2
  • 199
    • 78650821446 scopus 로고    scopus 로고
    • Apoptosis to autophagy switch triggered by the MHC class III-encoded receptor for advanced glycation endproducts (RAGE)
    • Kang, R., Tang, D., Loze, M. T., & Zeh, H. J. (2011). Apoptosis to autophagy switch triggered by the MHC class III-encoded receptor for advanced glycation endproducts (RAGE). Autophagy, 7, 91-93.
    • (2011) Autophagy , vol.7 , pp. 91-93
    • Kang, R.1    Tang, D.2    Loze, M.T.3    Zeh, H.J.4
  • 200
    • 0036591863 scopus 로고    scopus 로고
    • Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid β-peptide (1-42)
    • DOI 10.1016/S0891-5849(02)00821-3, PII S0891584902008213
    • Kanski, J., Aksenova, M., Schoneich, C., & Butterfield, D. A. (2002). Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide. Free Radical Biology and Medicine, 32, 1205-1211. (Pubitemid 34603357)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.11 , pp. 1205-1211
    • Kanski, J.1    Aksenova, M.2    Schoneich, C.3    Butterfield D.Allan4
  • 201
    • 0025665181 scopus 로고
    • The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease
    • Kawai, M., Kalaria, R. N., Harik, S. I., & Perry, G. (1990). The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. American Journal of Pathology, 137, 1435-1446.
    • (1990) American Journal of Pathology , vol.137 , pp. 1435-1446
    • Kawai, M.1    Kalaria, R.N.2    Harik, S.I.3    Perry, G.4
  • 202
    • 33846036424 scopus 로고    scopus 로고
    • Alzheimer's and dementia in the oldest-old: A century of challenges
    • DOI 10.2174/156720506779025233
    • Kawas, C. H., & Corrada, M. M. (2006). Alzheimer's and dementia in the oldest-old: A century of challenges. Current Alzheimer Research, 3, 411-419. (Pubitemid 46066420)
    • (2006) Current Alzheimer Research , vol.3 , Issue.5 , pp. 411-419
    • Kawas, C.H.1    Corrada, M.M.2
  • 203
    • 33746768939 scopus 로고    scopus 로고
    • Effects of phosphatidylserine supplementation on exercising humans
    • DOI 10.2165/00007256-200636080-00003
    • Kingsley, M. (2006). Effects of phosphatidylserine supplementation on exercising humans. Sports Medicine, 36, 657-669. (Pubitemid 44161955)
    • (2006) Sports Medicine , vol.36 , Issue.8 , pp. 657-669
    • Kingsley, M.1
  • 204
    • 0031893259 scopus 로고    scopus 로고
    • Functional activation of glial cells in early and delayed episodes of the brain damage
    • Kitamura, Y. (1998). Functional activation of glial cells in early and delayed episodes of the brain damage. Nippon Yakurigaku Zasshi, 111, 147-156. (Pubitemid 28143992)
    • (1998) Folia Pharmacologica Japonica , vol.111 , Issue.3 , pp. 147-156
    • Kitamura, Y.1
  • 205
    • 0031056029 scopus 로고    scopus 로고
    • Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α
    • DOI 10.1016/S0006-8993(96)01229-2, PII S0006899396012292
    • Klegeris, A., Walker, D. G., & McGeer, P. L. (1997). Interaction of Alzheimer beta-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha. Brain Research, 747, 114-121. (Pubitemid 27063805)
    • (1997) Brain Research , vol.747 , Issue.1 , pp. 114-121
    • Klegeris, A.1    Walker, D.G.2    McGeer, P.L.3
  • 206
    • 12844271615 scopus 로고    scopus 로고
    • Correlation between astrocyte apoptosis and Alzheimer changes in gray matter lesions in Alzheimer's disease
    • Kobayashi, K., Hayashi, M., Nakano, H., Shimazaki, M., Sugimori, K., & Koshino, Y. (2004). Correlation between astrocyte apoptosis and Alzheimer changes in gray matter lesions in Alzheimer's disease. Journal of Alzheimer's Disease, 6, 623-632 (discussion 673-681). (Pubitemid 40164168)
    • (2004) Journal of Alzheimer's Disease , vol.6 , Issue.6 , pp. 623-632
    • Kobayashi, K.1    Hayashi, M.2    Nakano, H.3    Shimazaki, M.4    Sugimori, K.5    Koshino, Y.6
  • 207
    • 0034309865 scopus 로고    scopus 로고
    • Long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: Stimulation of NGF and TrkA immunoreactivities in astroglia but not in microglia
    • DOI 10.1016/S0736-5748(99)00111-2, PII S0736574899001112
    • Koczyk, D., & Oderfeld-Nowak, B. (2000). Long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: Stimulation of NGF and TrkA immunoreactivities in astroglia but not in microglia. International Journal of Developmental Neuroscience, 18, 591-606. (Pubitemid 30407000)
    • (2000) International Journal of Developmental Neuroscience , vol.18 , Issue.6 , pp. 591-606
    • Koczyk, D.1    Oderfeld-Nowak, B.2
  • 209
    • 79960295989 scopus 로고    scopus 로고
    • Cell signaling and receptors with resorcinols and flavonoids: Redox, reactive oxygen species, and physiological effects
    • Kovacic, P., & Somanathan, R. (2011). Cell signaling and receptors with resorcinols and flavonoids: Redox, reactive oxygen species, and physiological effects. Journal of Receptor and Signal Transduction Research, 31, 265-270.
    • (2011) Journal of Receptor and Signal Transduction Research , vol.31 , pp. 265-270
    • Kovacic, P.1    Somanathan, R.2
  • 210
    • 0031565991 scopus 로고    scopus 로고
    • Paired helical filament morphology varies with intracellular location in Alzheimer's disease brain
    • DOI 10.1016/S0304-3940(97)00876-8, PII S0304394097008768
    • Kurt, M. A., Davies, D. C., & Kidd, M. (1997). Paired helical filament morphology varies with intracellular location in Alzheimer's disease brain. Neuroscience Letters, 239, 41-44. (Pubitemid 28055845)
    • (1997) Neuroscience Letters , vol.239 , Issue.1 , pp. 41-44
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3
  • 212
    • 5644232990 scopus 로고    scopus 로고
    • Mechanisms involved in the blood-brain barrier increased permeability induced by Phoneutria nigriventer spider venom in rats
    • DOI 10.1016/j.brainres.2004.08.055, PII S0006899304013411
    • Le Sueur, L. P., Collares-Buzato, C. B., & da Cruz-Hofling, M. A. (2004). Mechanisms involved in the blood-brain barrier increased permeability induced by Phoneutria nigriventer spider venom in rats. Brain Research, 1027, 38-47. (Pubitemid 39370993)
    • (2004) Brain Research , vol.1027 , Issue.1-2 , pp. 38-47
    • Le Sueur, L.P.1    Collares-Buzato, C.B.2    Alice Da Cruz-Hofling, M.3
  • 213
    • 0034703594 scopus 로고    scopus 로고
    • Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease
    • DOI 10.1016/S0304-3940(00)01418-X, PII S030439400001418X
    • Leake, A., Morris, C. M., & Whateley, J. (2000). Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease. Neuroscience Letters, 291, 201-203. (Pubitemid 30657926)
    • (2000) Neuroscience Letters , vol.291 , Issue.3 , pp. 201-203
    • Leake, A.1    Morris, C.M.2    Whateley, J.3
  • 214
    • 28744445475 scopus 로고    scopus 로고
    • Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain
    • DOI 10.1159/000088929
    • Lecanu, L., Greeson, J., & Papadopoulos, V. (2006). Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain. Pharmacology, 76, 19-33. (Pubitemid 41759058)
    • (2006) Pharmacology , vol.76 , Issue.1 , pp. 19-33
    • Lecanu, L.1    Greeson, J.2    Papadopoulos, V.3
  • 215
    • 0030924310 scopus 로고    scopus 로고
    • Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation
    • DOI 10.1073/pnas.94.10.5422
    • Lee, R. K., Araki, W., & Wurtman, R. J. (1997). Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation. Proceedings of the National Academy of Sciences of the United States of America, 94, 5422-5426. (Pubitemid 27214799)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.10 , pp. 5422-5426
    • Lee, R.K.K.1    Araki, W.2    Wurtman, R.J.3
  • 217
    • 14844311199 scopus 로고    scopus 로고
    • The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells
    • Lee, E. O., Kang, J. L., & Chong, Y. H. (2005). The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells. The Journal of Biological Chemistry, 280, 7845-7853.
    • (2005) The Journal of Biological Chemistry , vol.280 , pp. 7845-7853
    • Lee, E.O.1    Kang, J.L.2    Chong, Y.H.3
  • 218
    • 57249111794 scopus 로고    scopus 로고
    • Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress
    • Lee, K. W., Kim, J. B., Seo, J. S., Kim, T. K., Im, J. Y., Baek, I. S., et al. (2009). Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress. Journal of Neurochemistry, 108, 165-175.
    • (2009) Journal of Neurochemistry , vol.108 , pp. 165-175
    • Lee, K.W.1    Kim, J.B.2    Seo, J.S.3    Kim, T.K.4    Im, J.Y.5    Baek, I.S.6
  • 219
    • 77956861159 scopus 로고    scopus 로고
    • PPARgamma inhibits inflammatory reaction in oxidative stress induced human diploid fibloblast
    • Lee, Y. H., Lee, N. H., Bhattarai, G., Yun, J. S., Kim, T. I., Jhee, E. C., et al. (2010b). PPARgamma inhibits inflammatory reaction in oxidative stress induced human diploid fibloblast. Cell Biochemistry and Function, 28, 490-496.
    • (2010) Cell Biochemistry and Function , vol.28 , pp. 490-496
    • Lee, Y.H.1    Lee, N.H.2    Bhattarai, G.3    Yun, J.S.4    Kim, T.I.5    Jhee, E.C.6
  • 220
  • 221
    • 33747448625 scopus 로고    scopus 로고
    • Studies on the first described Alzheimer's disease amyloid β mutant, the Dutch variant
    • Levy, E., Prelli, F., & Frangione, B. (2006). Studies on the first described Alzheimer's disease amyloid beta mutant, the Dutch variant. Journal of Alzheimer's Disease, 9, 329-339. (Pubitemid 44253327)
    • (2006) Journal of Alzheimer's Disease , vol.9 , Issue.SUPPL. 3 , pp. 329-339
    • Levy, E.1    Prelli, F.2    Frangione, B.3
  • 222
    • 23844457609 scopus 로고    scopus 로고
    • Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain
    • DOI 10.1111/j.1742-4658.2005.04833.x
    • Li, X., Alafuzoff, I., Soininen, H., Winblad, B., & Pei, J. J. (2005). Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain. FEBS J, 272, 4211-4220. (Pubitemid 41160927)
    • (2005) FEBS Journal , vol.272 , Issue.16 , pp. 4211-4220
    • Li, X.1    Alafuzoff, I.2    Soininen, H.3    Winblad, B.4    Pei, J.-J.5
  • 224
    • 76749099393 scopus 로고    scopus 로고
    • Degradation of soluble and fibrillar amyloid beta-protein by matrix metalloproteinase (MT1-MMP) in vitro
    • Liao, M. C., & Van Nostrand, W. E. (2010). Degradation of soluble and fibrillar amyloid beta-protein by matrix metalloproteinase (MT1-MMP) in vitro. Biochemistry, 49, 1127-1136.
    • (2010) Biochemistry , vol.49 , pp. 1127-1136
    • Liao, M.C.1    Van Nostrand, W.E.2
  • 225
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., & Cole, G. M. (2001a). The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. Journal of Neuroscience, 21, 8370-8377. (Pubitemid 33051435)
    • (2001) Journal of Neuroscience , vol.21 , Issue.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 227
    • 0034633801 scopus 로고    scopus 로고
    • Involvement of oxidative stress, NF-IL-6, and RANTES expression in dengue-2-virus-infected human liver cells
    • Lin, Y. L., Liu, C. C., Chuang, J. I., Lei, H. Y., Yeh, T. M., Lin, Y. S., et al. (2000). Involvement of oxidative stress, NF-IL-6, and RANTES expression in dengue-2-virus-infected human liver cells. Virology, 276, 114-126.
    • (2000) Virology , vol.276 , pp. 114-126
    • Lin, Y.L.1    Liu, C.C.2    Chuang, J.I.3    Lei, H.Y.4    Yeh, T.M.5    Lin, Y.S.6
  • 228
    • 77952413110 scopus 로고    scopus 로고
    • Transport of Alzheimer disease amyloid-beta-binding D-amino acid peptides across an in vitro blood-brain barrier model
    • Liu, H., Funke, S. A., & Willbold, D. (2010). Transport of Alzheimer disease amyloid-beta-binding D-amino acid peptides across an in vitro blood-brain barrier model. Rejuvenation Research, 13, 210-213.
    • (2010) Rejuvenation Research , vol.13 , pp. 210-213
    • Liu, H.1    Funke, S.A.2    Willbold, D.3
  • 229
    • 67650444350 scopus 로고    scopus 로고
    • Upregulation of RAGE at the blood-brain barrier in streptozotocin-induced diabetic mice
    • Liu, L. P., Hong, H., Liao, J. M., Wang, T. S., Wu, J., Chen, S. S., et al. (2009a). Upregulation of RAGE at the blood-brain barrier in streptozotocin-induced diabetic mice. Synapse, 63, 636-642.
    • (2009) Synapse , vol.63 , pp. 636-642
    • Liu, L.P.1    Hong, H.2    Liao, J.M.3    Wang, T.S.4    Wu, J.5    Chen, S.S.6
  • 232
    • 33748450699 scopus 로고    scopus 로고
    • Oxidative stress: Apoptosis in neuronal injury
    • DOI 10.2174/156720506778249515
    • Loh, K. P., Huang, S. H., De Silva, R., Tan, B. K., & Zhu, Y. Z. (2006). Oxidative stress: Apoptosis in neuronal injury. Current Alzheimer Research, 3, 327-337. (Pubitemid 44351476)
    • (2006) Current Alzheimer Research , vol.3 , Issue.4 , pp. 327-337
    • Kok, P.L.1    Shan, H.H.2    De Silva, R.3    Tan, B.K.H.4    Yi, Z.Z.5
  • 234
    • 0032924640 scopus 로고    scopus 로고
    • Oxidative stress in brain ischemia
    • Love, S. (1999). Oxidative stress in brain ischemia. Brain Pathology, 9, 119-131. (Pubitemid 29056523)
    • (1999) Brain Pathology , vol.9 , Issue.1 , pp. 119-131
    • Love, S.1
  • 235
    • 19944424142 scopus 로고    scopus 로고
    • Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease
    • DOI 10.2174/1568007054038210
    • Lue, L. F., Yan, S. D., Stern, D. M., & Walker, D. G. (2005). Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease. Current Drug Targets. CNS and Neurological Disorders, 4, 249-266. (Pubitemid 40754161)
    • (2005) Current Drug Targets: CNS and Neurological Disorders , vol.4 , Issue.3 , pp. 249-266
    • Lue, L.-F.1    Yan, S.D.2    Stern, D.M.3    Walker, D.G.4
  • 236
    • 0034233474 scopus 로고    scopus 로고
    • Oxidative processes in Alzheimer's disease: The role of Aβ-metal interactions
    • DOI 10.1016/S0531-5565(00)00112-1, PII S0531556500001121
    • Lynch, T., Cherny, R. A., & Bush, A. I. (2000). Oxidative processes in Alzheimer's disease: The role of abeta-metal interactions. Experimental Gerontology, 35, 445-451. (Pubitemid 30665820)
    • (2000) Experimental Gerontology , vol.35 , Issue.4 , pp. 445-451
    • Lynch, T.1    Cherny, R.A.2    Bush, A.I.3
  • 237
    • 0023302279 scopus 로고
    • The relationship of astrocyte activation and fibrous gliosis to the development of Alzheimer type I cells in Wilson disease
    • Ma, G. J. (1987). The relationship of astrocyte activation and fibrous gliosis to the development of Alzheimer type I cells in Wilson disease. Zhonghua Bing Li Xue Za Zhi, 16, 7-10.
    • (1987) Zhonghua Bing Li Xue za Zhi , vol.16 , pp. 7-10
    • Ma, G.J.1
  • 241
    • 79251544549 scopus 로고    scopus 로고
    • Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: Implications for early detection and therapy
    • Marchesi, V. T. (2011). Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: Implications for early detection and therapy. FASEB J, 25, 5-13.
    • (2011) FASEB J , vol.25 , pp. 5-13
    • Marchesi, V.T.1
  • 242
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery, W. R., & Carney, J. M. (1999). Oxidative alterations in Alzheimer's disease. Brain Pathology, 9, 133-146. (Pubitemid 29056524)
    • (1999) Brain Pathology , vol.9 , Issue.1 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 243
    • 58849147059 scopus 로고    scopus 로고
    • Metalloproteinase's activity and oxidative stress in mild cognitive impairment and Alzheimer's disease
    • Martin-Aragon, S., Bermejo-Bescos, P., Benedi, J., Felici, E., Gil, P., Ribera, J. M., et al. (2009). Metalloproteinase's activity and oxidative stress in mild cognitive impairment and Alzheimer's disease. Neurochemical Research, 34, 373-378.
    • (2009) Neurochemical Research , vol.34 , pp. 373-378
    • Martin-Aragon, S.1    Bermejo-Bescos, P.2    Benedi, J.3    Felici, E.4    Gil, P.5    Ribera, J.M.6
  • 244
    • 0032524290 scopus 로고    scopus 로고
    • Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis
    • DOI 10.1074/jbc.273.20.12548
    • Masliah, E., Raber, J., Alford, M., Mallory, M., Mattson, M. P., Yang, D., et al. (1998). Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis. The Journal of Biological Chemistry, 273, 12548-12554. (Pubitemid 28240630)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.20 , pp. 12548-12554
    • Masliah, E.1    Raber, J.2    Alford, M.3    Mallory, M.4    Mattson, M.P.5    Yang, D.6    Wong, D.7    Mucke, L.8
  • 245
    • 53949085542 scopus 로고    scopus 로고
    • Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades
    • Matos, M., Augusto, E., Oliveira, C. R., & Agostinho, P. (2008). Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogen-activated protein kinase cascades. Neuroscience, 156, 898-910.
    • (2008) Neuroscience , vol.156 , pp. 898-910
    • Matos, M.1    Augusto, E.2    Oliveira, C.R.3    Agostinho, P.4
  • 246
    • 0028650421 scopus 로고
    • Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise
    • Mattson, M. P. (1994). Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise. Annals of the New York Academy of Sciences, 747, 50-76.
    • (1994) Annals of the New York Academy of Sciences , vol.747 , pp. 50-76
    • Mattson, M.P.1
  • 247
    • 0042536471 scopus 로고    scopus 로고
    • Neuronal and glial calcium signaling in Alzheimer's disease
    • DOI 10.1016/S0143-4160(03)00128-3
    • Mattson, M. P., & Chan, S. L. (2003). Neuronal and glial calcium signaling in Alzheimer's disease. Cell Calcium, 34, 385-397. (Pubitemid 37021231)
    • (2003) Cell Calcium , vol.34 , Issue.4-5 , pp. 385-397
    • Mattson, M.P.1    Chan, S.L.2
  • 248
    • 0026570528 scopus 로고
    • Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson, M. P., Cheng, B., Davis, D., Bryant, K., Lieberburg, I., & Rydel, R. E. (1992). Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. Journal of Neuroscience, 12, 376-389.
    • (1992) Journal of Neuroscience , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 249
    • 0033396991 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases
    • Mattson, M. P., Pedersen, W. A., Duan, W., Culmsee, C., & Camandola, S. (1999). Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Annals of the New York Academy of Sciences, 893, 154-175. (Pubitemid 30038074)
    • (1999) Annals of the New York Academy of Sciences , vol.893 , pp. 154-175
    • Mattson, M.P.1    Pedersen, W.A.2    Duan, W.3    Culmsee, C.4    Camandola, S.5
  • 250
    • 62249094525 scopus 로고    scopus 로고
    • Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology
    • McAlpine, F. E., Lee, J. K., Harms, A. S., Ruhn, K. A., Blurton-Jones, M., Hong, J., et al. (2009). Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Diseases, 34, 163-177.
    • (2009) Neurobiology of Diseases , vol.34 , pp. 163-177
    • McAlpine, F.E.1    Lee, J.K.2    Harms, A.S.3    Ruhn, K.A.4    Blurton-Jones, M.5    Hong, J.6
  • 252
    • 0028942798 scopus 로고
    • Inhibition of cytokine activation processes in vitro by tenidap, a novel anti-inflammatory agent
    • McNiff, P. A., Laliberte, R. E., Svensson, L., Pazoles, C. J., & Gabel, C. A. (1995). Inhibition of cytokine activation processes in vitro by tenidap, a novel anti-inflammatory agent. Cytokine, 7, 196-208.
    • (1995) Cytokine , vol.7 , pp. 196-208
    • McNiff, P.A.1    Laliberte, R.E.2    Svensson, L.3    Pazoles, C.J.4    Gabel, C.A.5
  • 254
    • 0034237388 scopus 로고    scopus 로고
    • Induction of cytokines in glial cells surrounding cortical β-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology
    • DOI 10.1016/S0736-5748(00)00012-5, PII S0736574800000125
    • Mehlhorn, G., Hollborn, M., & Schliebs, R. (2000). Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology. International Journal of Developmental Neuroscience, 18, 423-431. (Pubitemid 30243072)
    • (2000) International Journal of Developmental Neuroscience , vol.18 , Issue.4-5 , pp. 423-431
    • Mehlhorn, G.1    Hollborn, M.2    Schliebs, R.3
  • 255
    • 2342417953 scopus 로고    scopus 로고
    • Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: Common links and potential therapeutic targets
    • Mhatre, M., Floyd, R. A., & Hensley, K. (2004). Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: Common links and potential therapeutic targets. Journal of Alzheimer's Disease, 6, 147-157. (Pubitemid 38560250)
    • (2004) Journal of Alzheimer's Disease , vol.6 , Issue.2 , pp. 147-157
    • Mhatrea, M.1    Floyd, R.A.2    Hensley, K.3
  • 256
    • 70449393799 scopus 로고    scopus 로고
    • Specific human astrocyte subtype revealed by affinity purified GFAP antibody; unpurified serum cross-reacts with neurofilament-L in Alzheimer
    • Middeldorp, J., van den Berge, S. A., Aronica, E., Speijer, D., & Hol, E. M. (2009). Specific human astrocyte subtype revealed by affinity purified GFAP antibody; unpurified serum cross-reacts with neurofilament-L in Alzheimer. PLoS One, 4, e7663.
    • (2009) PLoS One , vol.4
    • Middeldorp, J.1    Van Den Berge, S.A.2    Aronica, E.3    Speijer, D.4    Hol, E.M.5
  • 258
    • 0034643895 scopus 로고    scopus 로고
    • Oxidative stress induces intracellular accumulation of amyloid β- protein (Aβ) in human neuroblastoma cells
    • DOI 10.1021/bi000169p
    • Misonou, H., Morishima-Kawashima, M., & Ihara, Y. (2000). Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells. Biochemistry, 39, 6951-6959. (Pubitemid 30390389)
    • (2000) Biochemistry , vol.39 , Issue.23 , pp. 6951-6959
    • Misonou, H.1    Morishima-Kawashima, M.2    Ihara, Y.3
  • 259
    • 77956899143 scopus 로고    scopus 로고
    • Vascular pathology in Alzheimer's disease
    • Miyakawa, T. (2010). Vascular pathology in Alzheimer's disease. Psychogeriatrics, 10, 39-44.
    • (2010) Psychogeriatrics , vol.10 , pp. 39-44
    • Miyakawa, T.1
  • 260
    • 70350345529 scopus 로고    scopus 로고
    • Matrix metalloproteinases-2 and -3 are reduced in cerebrospinal fluid with low beta-amyloid1-42 levels
    • Mlekusch, R., & Humpel, C. (2009). Matrix metalloproteinases-2 and -3 are reduced in cerebrospinal fluid with low beta-amyloid1-42 levels. Neuroscience Letters, 466, 135-138.
    • (2009) Neuroscience Letters , vol.466 , pp. 135-138
    • Mlekusch, R.1    Humpel, C.2
  • 263
    • 0035696282 scopus 로고    scopus 로고
    • The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease
    • DOI 10.1016/S0197-4580(01)00293-7, PII S0197458001002937
    • Mrak, R. E., & Griffinbc, W. S. (2001). The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease. Neurobiology of Aging, 22, 915-922. (Pubitemid 34066559)
    • (2001) Neurobiology of Aging , vol.22 , Issue.6 , pp. 915-922
    • Mrak, R.E.1    Griffin, W.S.T.2
  • 264
    • 33750159885 scopus 로고    scopus 로고
    • Amyloid precursor protein and BACE function as oligomers
    • DOI 10.1159/000095266
    • Multhaup, G. (2006). Amyloid precursor protein and BACE function as oligomers. Neurodegenerative Diseases, 3, 270-274. (Pubitemid 44600314)
    • (2006) Neurodegenerative Diseases , vol.3 , Issue.4-5 , pp. 270-274
    • Multhaup, G.1
  • 265
    • 44949138575 scopus 로고    scopus 로고
    • Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury
    • Nadler, Y., Alexandrovich, A., Grigoriadis, N., Hartmann, T., Rao, K. S., Shohami, E., et al. (2008). Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury. Glia, 56, 552-567.
    • (2008) Glia , vol.56 , pp. 552-567
    • Nadler, Y.1    Alexandrovich, A.2    Grigoriadis, N.3    Hartmann, T.4    Rao, K.S.5    Shohami, E.6
  • 266
    • 42149125510 scopus 로고    scopus 로고
    • Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease
    • DOI 10.2174/156720508783954785
    • Nalivaeva, N. N., Fisk, L. R., Belyaev, N. D., & Turner, A. J. (2008). Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease. Current Alzheimer Research, 5, 212-224. (Pubitemid 351536346)
    • (2008) Current Alzheimer Research , vol.5 , Issue.2 , pp. 212-224
    • Nalivaeva, N.N.1    Fisk, L.R.2    Belyaev, N.D.3    Turner, A.J.4
  • 267
    • 23944444792 scopus 로고    scopus 로고
    • Peroxynitrite production and NOS expression in astrocytes U373MG incubated with lipoproteins from Alzheimer patients
    • DOI 10.1016/j.brainres.2005.06.025, PII S0006899305008930
    • Nanetti, L., Vignini, A., Moroni, C., Bartolini, M., Luzzi, S., Provinciali, L., et al. (2005). Peroxynitrite production and NOS expression in astrocytes U373MG incubated with lipoproteins from Alzheimer patients. Brain Research, 1054, 38-44. (Pubitemid 41188127)
    • (2005) Brain Research , vol.1054 , Issue.1 , pp. 38-44
    • Nanetti, L.1    Vignini, A.2    Moroni, C.3    Bartolini, M.4    Luzzi, S.5    Provinciali, L.6    Mazzanti, L.7
  • 268
    • 0028030129 scopus 로고
    • Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis
    • Newby, A. C., Southgate, K. M., & Davies, M. (1994). Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis. Basic Research in Cardiology, 89(Suppl 1), 59-70. (Pubitemid 24314598)
    • (1994) Basic Research in Cardiology, Supplement , vol.89 , Issue.1 , pp. 59-70
    • Newby, A.C.1    Southgate, K.M.2    Davies, M.3
  • 270
    • 67650729358 scopus 로고    scopus 로고
    • Lipid peroxidation: Physiological levels and dual biological effects
    • Niki, E. (2009). Lipid peroxidation: physiological levels and dual biological effects. Free Radical Biology and Medicine, 47, 469-484.
    • (2009) Free Radical Biology and Medicine , vol.47 , pp. 469-484
    • Niki, E.1
  • 271
    • 33748451468 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease
    • DOI 10.2174/156720506778249489
    • Onyango, I. G., & Khan, S. M. (2006). Oxidative stress, mitochondrial dysfunction, and stress signaling in Alzheimer's disease. Current Alzheimer Research, 3, 339-349. (Pubitemid 44351477)
    • (2006) Current Alzheimer Research , vol.3 , Issue.4 , pp. 339-349
    • Onyango, I.G.1    Khand, S.M.2
  • 272
    • 0017295228 scopus 로고
    • Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia
    • Op den Velde, W., & Stam, F. C. (1976). Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Journal of the American Geriatrics Society, 24, 12-16.
    • (1976) Journal of the American Geriatrics Society , vol.24 , pp. 12-16
    • Op Den Velde, W.1    Stam, F.C.2
  • 273
    • 33847325683 scopus 로고    scopus 로고
    • Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)-2′,3′-dideoxycytidine (ddC): Relevance to HIV-dementia
    • DOI 10.1016/j.expneurol.2006.09.010, PII S0014488606005498
    • Opii, W. O., Sultana, R., Abdul, H. M., Ansari, M. A., Nath, A., & Butterfield, D. A. (2007). Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)-2',3'-dideoxycytidine (ddC): Relevance to HIV-dementia. Experimental Neurology, 204, 29-38. (Pubitemid 46330254)
    • (2007) Experimental Neurology , vol.204 , Issue.1 , pp. 29-38
    • Opii, W.O.1    Sultana, R.2    Abdul, H.M.3    Ansari, M.A.4    Nath, A.5    Butterfield, D.A.6
  • 274
    • 1842767259 scopus 로고    scopus 로고
    • Mitochondrial regulation of apoptotic cell death
    • DOI 10.1016/j.toxlet.2003.12.017, PII S037842740300479X
    • Orrenius, S. (2004). Mitochondrial regulation of apoptotic cell death. Toxicology Letters, 149, 19-23. (Pubitemid 38469816)
    • (2004) Toxicology Letters , vol.149 , Issue.1-3 , pp. 19-23
    • Orrenius, S.1
  • 275
    • 78049386757 scopus 로고    scopus 로고
    • Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: Implications for Abeta accumulation in AD brain
    • Owen, J. B., Sultana, R., Aluise, C. D., Erickson, M. A., Price, T. O., Bu, G., et al. (2010). Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: Implications for Abeta accumulation in AD brain. Free Radical Biology and Medicine, 49, 1798-1803.
    • (2010) Free Radical Biology and Medicine , vol.49 , pp. 1798-1803
    • Owen, J.B.1    Sultana, R.2    Aluise, C.D.3    Erickson, M.A.4    Price, T.O.5    Bu, G.6
  • 277
    • 58149380018 scopus 로고    scopus 로고
    • From aging to Alzheimer's disease: Unveiling "the switch," with the senescence-accelerated mouse model (SAMP8)
    • Pallas, M., Camins, A., Smith, M. A., Perry, G., Lee, H. G., & Casadesus, G. (2008). From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). Journal of Alzheimer's Disease, 15, 615-624.
    • (2008) Journal of Alzheimer's Disease , vol.15 , pp. 615-624
    • Pallas, M.1    Camins, A.2    Smith, M.A.3    Perry, G.4    Lee, H.G.5    Casadesus, G.6
  • 278
    • 0036734997 scopus 로고    scopus 로고
    • Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide
    • Pan, W., Solomon, B., Maness, L. M., & Kastin, A. J. (2002). Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide. Experimental Biology and Medicine (Maywood), 227, 609-615.
    • (2002) Experimental Biology and Medicine (Maywood) , vol.227 , pp. 609-615
    • Pan, W.1    Solomon, B.2    Maness, L.M.3    Kastin, A.J.4
  • 279
    • 0030788993 scopus 로고    scopus 로고
    • Cysteine proteinases are responsible for characteristic transketolase alterations in Alzheimer fibroblasts
    • DOI 10.1002/(SICI)1097-4652(199707)172:1<63::AID-JCP7>3.0.CO;2-B
    • Paoletti, F., Mocali, A., & Tombaccini, D. (1997). Cysteine proteinases are responsible for characteristic transketolase alterations in Alzheimer fibroblasts. Journal of Cellular Physiology, 172, 63-68. (Pubitemid 27283348)
    • (1997) Journal of Cellular Physiology , vol.172 , Issue.1 , pp. 63-68
    • Paoletti, F.1    Mocali, A.2    Tombaccini, D.3
  • 280
    • 0035691010 scopus 로고    scopus 로고
    • Genetics of interleukin 6: Implications for Alzheimer's disease
    • DOI 10.1016/S0197-4580(01)00294-9, PII S0197458001002949
    • Papassotiropoulos, A., Hock, C., & Nitsch, R. M. (2001). Genetics of interleukin 6: Implications for Alzheimer's disease. Neurobiology of Aging, 22, 863-871. (Pubitemid 34066553)
    • (2001) Neurobiology of Aging , vol.22 , Issue.6 , pp. 863-871
    • Papassotiropoulos, A.1    Hock, C.2    Nitsch, R.M.3
  • 281
    • 0023835388 scopus 로고
    • Does the brain's gatekeeper falter in aging?
    • Pardridge, W. M. (1988). Does the brain's gatekeeper falter in aging? Neurobiology of Aging, 9, 44-46.
    • (1988) Neurobiology of Aging , vol.9 , pp. 44-46
    • Pardridge, W.M.1
  • 282
    • 0034745636 scopus 로고    scopus 로고
    • Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro
    • DOI 10.1046/j.1471-4159.2001.00112.x
    • Parks, J. K., Smith, T. S., Trimmer, P. A., Bennett, J. P., Jr., & Parker, W. D., Jr. (2001). Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. Journal of Neurochemistry, 76, 1050-1056. (Pubitemid 32167378)
    • (2001) Journal of Neurochemistry , vol.76 , Issue.4 , pp. 1050-1056
    • Parks, J.K.1    Smith, T.S.2    Trimmer, P.A.3    Bennett Jr., J.P.4    Davis Parker, W.Jr.5
  • 283
    • 0029989339 scopus 로고    scopus 로고
    • Immune and inflammatory responses in TNFα-deficient mice: A critical requirement for TNFα in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
    • DOI 10.1084/jem.184.4.1397
    • Pasparakis, M., Alexopoulou, L., Episkopou, V., & Kollias, G. (1996). Immune and inflammatory responses in TNF alpha-deficient mice: A critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. Journal of Experimental Medicine, 184, 1397-1411. (Pubitemid 26354696)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.4 , pp. 1397-1411
    • Pasparakis, M.1    Alexopoulou, L.2    Episkopou, V.3    Kollias, G.4
  • 284
    • 0036680051 scopus 로고    scopus 로고
    • Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s
    • DOI 10.1016/S0300-483X(02)00193-2, PII S0300483X02001932
    • Pattison, D. I., Dean, R. T., & Davies, M. J. (2002). Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s. Toxicology, 177, 23-37. (Pubitemid 34786242)
    • (2002) Toxicology , vol.177 , Issue.1 , pp. 23-37
    • Pattison, D.I.1    Dean, R.T.2    Davies, M.J.3
  • 285
    • 0031723106 scopus 로고    scopus 로고
    • Matrix metalloproteinases contribute to the blood-brain barrier disruption during bacterial meningitis
    • DOI 10.1002/ana.410440404
    • Paul, R., Lorenzl, S., Koedel, U., Sporer, B., Vogel, U., Frosch, M., et al. (1998). Matrix metalloproteinases contribute to the bloodbrain barrier disruption during bacterial meningitis. Annals of Neurology, 44, 592-600. (Pubitemid 28477846)
    • (1998) Annals of Neurology , vol.44 , Issue.4 , pp. 592-600
    • Paul, R.1    Lorenzl, S.2    Koedel, U.3    Sporer, B.4    Vogel, U.5    Frosch, M.6    Pfister, H.-W.7
  • 286
    • 0032571932 scopus 로고    scopus 로고
    • Genetiska faktorer ligger ofta bakom Alzheimers sjukdom: Stor tvillingstudie skall klarlägga sambanden arv-miljö
    • Pedersen, N. L., Berg, S., Johansson, B., Johansson, K., Viitanen, M., Winblad, B., et al. (1998). Genetic factors are often found in Alzheimer disease. An extensive twin study to clarify the heredity-environment relationship. Lakartidningen, 95, 2585-2588. (Pubitemid 128641139)
    • (1998) Lakartidningen , Issue.22 , pp. 2585-2588
    • Pedersen, N.L.1    Berg, S.2    Johansson, B.3    Johansson, K.4    Viitanen, M.5    Winblad, B.6    Gatz, M.7
  • 287
    • 0033022771 scopus 로고    scopus 로고
    • Involvement of oxidative stress on the impairment of energy metabolism induced by Aβ peptides on PC12 cells: Protection by antioxidants
    • DOI 10.1006/nbdi.1999.0241
    • Pereira, C., Santos, M. S., & Oliveira, C. (1999). Involvement of oxidative stress on the impairment of energy metabolism induced by A beta peptides on PC12 cells: Protection by antioxidants. Neurobiology of Diseases, 6, 209-219. (Pubitemid 29297822)
    • (1999) Neurobiology of Disease , vol.6 , Issue.3 , pp. 209-219
    • Pereira, C.1    Santos, M.S.2    Oliveira, C.3
  • 288
    • 80053652475 scopus 로고    scopus 로고
    • LRP1 mediates bidirectional transcytosis of amyloid-beta across the blood-brain barrier
    • doi:10.1016/j.neurobiolaging.2010. 05.025
    • Pflanzner, T., Janko, M. C., Andre-Dohmen, B., Reuss, S., Weggen, S., Roebroek, A. J., et al. (2010). LRP1 mediates bidirectional transcytosis of amyloid-beta across the blood-brain barrier. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2010. 05.025.
    • (2010) Neurobiology of Aging
    • Pflanzner, T.1    Janko, M.C.2    Andre-Dohmen, B.3    Reuss, S.4    Weggen, S.5    Roebroek, A.J.6
  • 289
    • 0025992417 scopus 로고
    • In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
    • Pike, C. J., Walencewicz, A. J., Glabe, C. G., & Cotman, C. W. (1991). In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Research, 563, 311-314.
    • (1991) Brain Research , vol.563 , pp. 311-314
    • Pike, C.J.1    Walencewicz, A.J.2    Glabe, C.G.3    Cotman, C.W.4
  • 290
    • 14644419663 scopus 로고    scopus 로고
    • Ultraviolet radiation and skin aging: Roles of reactive oxygen species, inflammation and protease activation, and strategies for prevention of inflammation-induced matrix degradation - A review
    • DOI 10.1111/j.1467-2494.2004.00241.x
    • Pillai, S., Oresajo, C., & Hayward, J. (2005). Ultraviolet radiation and skin aging: Roles of reactive oxygen species, inflammation and protease activation, and strategies for prevention of inflammation-induced matrix degradation - A review. International Journal of Cosmetic Science, 27, 17-34. (Pubitemid 40313411)
    • (2005) International Journal of Cosmetic Science , vol.27 , Issue.1 , pp. 17-34
    • Pillai, S.1    Oresajo, C.2    Hayward, J.3
  • 292
    • 0026865423 scopus 로고
    • Structural and functional changes of blood-brain barrier and indication of prion amyloid filaments in experimental amyotrophic leucospongiosis
    • Poleshchuk, N. N., Votyakov, V. I., Ilkevich Yu, G., Duboiskaya, G. P., Grigoriev, D. G., & Kolomiets, N. D. (1992). Structural and functional changes of blood-brain barrier and indication of prion amyloid filaments in experimental amyotrophic leucospongiosis. Acta Virologica, 36, 293-303.
    • (1992) Acta Virologica , vol.36 , pp. 293-303
    • Poleshchuk, N.N.1    Votyakov, V.I.2    Ilkevich, Yu.G.3    Duboiskaya, G.P.4    Grigoriev, D.G.5    Kolomiets, N.D.6
  • 294
    • 0035875690 scopus 로고    scopus 로고
    • Increased lipid peroxidation precedes amyloid plaque formation in an animal model of alzheimer amyloidosis
    • Pratico, D., Uryu, K., Leight, S., Trojanoswki, J. Q., & Lee, V. M. (2001). Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. Journal of Neuroscience, 21, 4183-4187. (Pubitemid 32538543)
    • (2001) Journal of Neuroscience , vol.21 , Issue.12 , pp. 4183-4187
    • Pratico, D.1    Uryu, K.2    Leight, S.3    Trojanoswki, J.Q.4    Lee, V.M.-Y.5
  • 296
    • 67650153191 scopus 로고    scopus 로고
    • Involvement of ROS in BBB dysfunction
    • Pun, P. B., Lu, J., & Moochhala, S. (2009). Involvement of ROS in BBB dysfunction. Free Radical Research, 43, 348-364.
    • (2009) Free Radical Research , vol.43 , pp. 348-364
    • Pun, P.B.1    Lu, J.2    Moochhala, S.3
  • 297
    • 0037193473 scopus 로고    scopus 로고
    • Intrinsic and extrinsic pathway signaling during neuronal apoptosis: Lessons from the analysis of mutant mice
    • DOI 10.1083/jcb.200110108
    • Putcha, G. V., Harris, C. A., Moulder, K. L., Easton, R. M., Thompson, C. B., & Johnson, E. M., Jr. (2002). Intrinsic and extrinsic pathway signaling during neuronal apoptosis: Lessons from the analysis of mutant mice. Journal of Cell Biology, 157, 441-453. (Pubitemid 34839808)
    • (2002) Journal of Cell Biology , vol.157 , Issue.3 , pp. 441-453
    • Putcha, G.V.1    Harris, C.A.2    Moulder, K.L.3    Easton, R.M.4    Thompson, C.B.5    Johnson Jr., E.M.6
  • 299
    • 0032744796 scopus 로고    scopus 로고
    • Spatiotemporal progression of neuro-degeneration and glia activation in the wobbler neuropathy of the mouse
    • Rathke-Hartlieb, S., Schmidt, V. C., Jockusch, H., Schmitt-John, T., & Bartsch, J. W. (1999). Spatiotemporal progression of neuro-degeneration and glia activation in the wobbler neuropathy of the mouse. Neuroreport, 10, 3411-3416.
    • (1999) Neuroreport , vol.10 , pp. 3411-3416
    • Rathke-Hartlieb, S.1    Schmidt, V.C.2    Jockusch, H.3    Schmitt-John, T.4    Bartsch, J.W.5
  • 300
    • 78049450207 scopus 로고    scopus 로고
    • Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury
    • Readnower, R. D., Chavko, M., Adeeb, S., Conroy, M. D., Pauly, J. R., McCarron, R. M., et al. (2010). Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury. Journal of Neuroscience Research, 88, 3530-3539.
    • (2010) Journal of Neuroscience Research , vol.88 , pp. 3530-3539
    • Readnower, R.D.1    Chavko, M.2    Adeeb, S.3    Conroy, M.D.4    Pauly, J.R.5    McCarron, R.M.6
  • 301
    • 10744222732 scopus 로고    scopus 로고
    • Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines
    • DOI 10.1016/j.jneuroim.2003.11.003
    • Reale, M., Iarlori, C., Gambi, F., Feliciani, C., Salone, A., Toma, L., et al. (2004). Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines. Journal of Neuroimmunology, 148, 162-171. (Pubitemid 38229569)
    • (2004) Journal of Neuroimmunology , vol.148 , Issue.1-2 , pp. 162-171
    • Reale, M.1    Iarlori, C.2    Gambi, F.3    Feliciani, C.4    Salone, A.5    Toma, L.6    DeLuca, G.7    Salvatore, M.8    Conti, P.9    Gambi, D.10
  • 302
    • 40849120274 scopus 로고    scopus 로고
    • Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease
    • Reed, T., Perluigi, M., Sultana, R., Pierce, W. M., Klein, J. B., Turner, D. M., et al. (2008). Redox proteomic identification of 4-hydroxy-2-nonenal- modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease. Neurobiology of Diseases, 30, 107-120.
    • (2008) Neurobiology of Diseases , vol.30 , pp. 107-120
    • Reed, T.1    Perluigi, M.2    Sultana, R.3    Pierce, W.M.4    Klein, J.B.5    Turner, D.M.6
  • 303
    • 0027693553 scopus 로고
    • Interactions of the pineal hormone melatonin with oxygen-centered free radicals: A brief review
    • Reiter, R. J. (1993). Interactions of the pineal hormone melatonin with oxygen-centered free radicals: A brief review. Brazilian Journal of Medical and Biological Research, 26, 1141-1155.
    • (1993) Brazilian Journal of Medical and Biological Research , vol.26 , pp. 1141-1155
    • Reiter, R.J.1
  • 304
    • 59149101704 scopus 로고    scopus 로고
    • Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: Riboregulation against neural oxidative damage in Alzheimer's disease
    • Rogers, J. T., Bush, A. I., Cho, H. H., Smith, D. H., Thomson, A. M., Friedlich, A. L., et al. (2008). Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: Riboregulation against neural oxidative damage in Alzheimer's disease. Biochemical Society Transactions, 36, 1282-1287.
    • (2008) Biochemical Society Transactions , vol.36 , pp. 1282-1287
    • Rogers, J.T.1    Bush, A.I.2    Cho, H.H.3    Smith, D.H.4    Thomson, A.M.5    Friedlich, A.L.6
  • 305
    • 3442888291 scopus 로고    scopus 로고
    • Metal and inflammatory targets for Alzheimer's disease
    • DOI 10.2174/1389450043345272
    • Rogers, J. T., & Lahiri, D. K. (2004). Metal and inflammatory targets for Alzheimer's disease. Current Drug Targets, 5, 535-551. (Pubitemid 39004428)
    • (2004) Current Drug Targets , vol.5 , Issue.6 , pp. 535-551
    • Rogers, J.T.1    Lahiri, D.K.2
  • 306
    • 0036547481 scopus 로고    scopus 로고
    • Inhibition of BACE, a promising approach to Alzheimer's disease therapy
    • Roggo, S. (2002). Inhibition of BACE, a promising approach to Alzheimer's disease therapy. Current Topics in Medicinal Chemistry, 2, 359-370.
    • (2002) Current Topics in Medicinal Chemistry , vol.2 , pp. 359-370
    • Roggo, S.1
  • 307
    • 77953946746 scopus 로고    scopus 로고
    • Mechanisms involved in the modulation of astroglial resistance to oxidative stress induced by activated microglia: Antioxidative systems, peroxide elimination, radical generation, lipid peroxidation
    • Rohl, C., Armbrust, E., Herbst, E., Jess, A., Gulden, M., Maser, E., et al. (2010). Mechanisms involved in the modulation of astroglial resistance to oxidative stress induced by activated microglia: Antioxidative systems, peroxide elimination, radical generation, lipid peroxidation. Neurotoxicity Research, 17, 317-331.
    • (2010) Neurotoxicity Research , vol.17 , pp. 317-331
    • Rohl, C.1    Armbrust, E.2    Herbst, E.3    Jess, A.4    Gulden, M.5    Maser, E.6
  • 309
    • 0031693557 scopus 로고    scopus 로고
    • Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain
    • Rosenberg, G. A., Estrada, E. Y., & Dencoff, J. E. (1998). Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke, 29, 2189-2195. (Pubitemid 28443538)
    • (1998) Stroke , vol.29 , Issue.10 , pp. 2189-2195
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3
  • 312
    • 13244264935 scopus 로고    scopus 로고
    • Alzheimer's disease β-secretase BACE1 is not a neuron-specific enzyme
    • DOI 10.1111/j.1471-4159.2004.02857.x
    • Rossner, S., Lange-Dohna, C., Zeitschel, U., & Perez-Polo, J. R. (2005). Alzheimer's disease beta-secretase BACE1 is not a neuronspecific enzyme. Journal of Neurochemistry, 92, 226-234. (Pubitemid 40194014)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.2 , pp. 226-234
    • Rossner, S.1    Lange-Dohna, C.2    Zeitschel, U.3    Perez-Polo, J.R.4
  • 313
    • 0034830488 scopus 로고    scopus 로고
    • Caspases, apoptosis, and Alzheimer disease: Causation, correlation, and confusion
    • Roth, K. A. (2001). Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion. Journal of Neuropathology and Experimental Neurology, 60, 829-838.
    • (2001) Journal of Neuropathology and Experimental Neurology , vol.60 , pp. 829-838
    • Roth, K.A.1
  • 314
    • 33646050649 scopus 로고    scopus 로고
    • Oligodendrocytes damage in Alzheimer's disease: Beta amyloid toxicity and inflammation
    • Roth, A. D., Ramirez, G., Alarcon, R., & Von Bernhardi, R. (2005). Oligodendrocytes damage in Alzheimer's disease: Beta amyloid toxicity and inflammation. Biological Research, 38, 381-387.
    • (2005) Biological Research , vol.38 , pp. 381-387
    • Roth, A.D.1    Ramirez, G.2    Alarcon, R.3    Von Bernhardi, R.4
  • 315
    • 79953205141 scopus 로고    scopus 로고
    • Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: Roles for F-actin and GPR30
    • Rowlands, D. J., Chapple, S., Siow, R. C., & Mann, G. E. (2011). Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: Roles for F-actin and GPR30. Hypertension, 57, 833-840.
    • (2011) Hypertension , vol.57 , pp. 833-840
    • Rowlands, D.J.1    Chapple, S.2    Siow, R.C.3    Mann, G.E.4
  • 316
    • 4444360155 scopus 로고    scopus 로고
    • Interaction between matrix metalloproteinase 3 and the ε4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns
    • DOI 10.1016/j.neulet.2004.06.027, PII S0304394004007621
    • Saarela, M. S., Lehtimaki, T., Rinne, J. O., Hervonen, A., Jylha, M., Roytta, M., et al. (2004). Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns. Neuroscience Letters, 367, 336-339. (Pubitemid 39178608)
    • (2004) Neuroscience Letters , vol.367 , Issue.3 , pp. 336-339
    • Saarela, M.S.1    Lehtimaki, T.2    Rinne, J.O.3    Hervonen, A.4    Jylha, M.5    Roytta, M.6    Ahonen, J.-P.7    Mattila, K.M.8
  • 317
    • 70450196497 scopus 로고    scopus 로고
    • Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: Data from an association study
    • Saiz, P. A., Garcia-Portilla, M. P., Florez, G., Corcoran, P., Arango, C., Morales, B., et al. (2009). Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: Data from an association study. Alcoholism, Clinical and Experimental Research, 33, 2147-2153.
    • (2009) Alcoholism, Clinical and Experimental Research , vol.33 , pp. 2147-2153
    • Saiz, P.A.1    Garcia-Portilla, M.P.2    Florez, G.3    Corcoran, P.4    Arango, C.5    Morales, B.6
  • 319
    • 44949140698 scopus 로고    scopus 로고
    • Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle
    • Schmidt, J., Barthel, K., Wrede, A., Salajegheh, M., Bahr, M., & Dalakas, M. C. (2008). Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. Brain, 131, 1228-1240.
    • (2008) Brain , vol.131 , pp. 1228-1240
    • Schmidt, J.1    Barthel, K.2    Wrede, A.3    Salajegheh, M.4    Bahr, M.5    Dalakas, M.C.6
  • 320
    • 0029882671 scopus 로고    scopus 로고
    • RAGE: A novel cellular receptor for advanced glycation end products
    • Schmidt, A. M., Hori, O., Cao, R., Yan, S. D., Brett, J., Wautier, J. L., et al. (1996). RAGE: A novel cellular receptor for advanced glycation end products. Diabetes, 45(Suppl 3), S77-S80.
    • (1996) Diabetes , vol.45 , Issue.SUPPL. 3
    • Schmidt, A.M.1    Hori, O.2    Cao, R.3    Yan, S.D.4    Brett, J.5    Wautier, J.L.6
  • 321
    • 0033009614 scopus 로고    scopus 로고
    • Cerebrovascular involvement in systemic AA and AL amyloidosis: A clear haematogenic pattern
    • DOI 10.1007/s004280050383
    • Schroder, R., & Linke, R. P. (1999). Cerebrovascular involvement in systemic AA and AL amyloidosis: A clear haematogenic pattern. Virchows Archiv, 434, 551-560. (Pubitemid 29281315)
    • (1999) Virchows Archiv , vol.434 , Issue.6 , pp. 551-560
    • Schroder, R.1    Linke, R.P.2
  • 322
    • 0034799913 scopus 로고    scopus 로고
    • Glia-related pathomechanisms in Alzheimer's disease: A therapeutic target?
    • DOI 10.1016/S0047-6374(01)00343-8, PII S0047637401003438
    • Schubert, P., Ogata, T., Marchini, C., & Ferroni, S. (2001). Gliarelated pathomechanisms in Alzheimer's disease: A therapeutic target? Mechanisms of Ageing and Development, 123, 47-57. (Pubitemid 32972258)
    • (2001) Mechanisms of Ageing and Development , vol.123 , Issue.1 , pp. 47-57
    • Schubert, P.1    Ogata, T.2    Marchini, C.3    Ferroni, S.4
  • 323
    • 0032460149 scopus 로고    scopus 로고
    • Interfering with the pathologic activation of microglial cells and astrocytes in dementia
    • Schubert, P., & Rudolphi, K. (1998). Interfering with the pathologic activation of microglial cells and astrocytes in dementia. Alzheimer Disease and Associated Disorders, 12(Suppl 2), S21-S28. (Pubitemid 29108223)
    • (1998) Alzheimer Disease and Associated Disorders , vol.12 , Issue.SUPPL. 2
    • Schubert, P.1    Rudolphi, K.2
  • 324
  • 325
  • 326
    • 78449279609 scopus 로고    scopus 로고
    • Quercetin regulates insulin like growth factor signaling and induces intrinsic and extrinsic pathway mediated apoptosis in androgen independent prostate cancer cells (PC-3)
    • Senthilkumar, K., Elumalai, P., Arunkumar, R., Banudevi, S., Gunadharini, N. D., Sharmila, G., et al. (2010). Quercetin regulates insulin like growth factor signaling and induces intrinsic and extrinsic pathway mediated apoptosis in androgen independent prostate cancer cells (PC-3). Molecular and Cellular Biochemistry, 344, 173-184.
    • (2010) Molecular and Cellular Biochemistry , vol.344 , pp. 173-184
    • Senthilkumar, K.1    Elumalai, P.2    Arunkumar, R.3    Banudevi, S.4    Gunadharini, N.D.5    Sharmila, G.6
  • 328
    • 34548555711 scopus 로고    scopus 로고
    • Genetics of Alzheimer's disease. A rapidly evolving field
    • The Multifaceted Aspects of Alzheimer's Disease: From Social to Molecular Problems
    • Serretti, A., Olgiati, P., & De Ronchi, D. (2007). Genetics of Alzheimer's disease. A rapidly evolving field. Journal of Alzheimer's Disease, 12, 73-92. (Pubitemid 47396303)
    • (2007) Journal of Alzheimer's Disease , vol.12 , Issue.1 , pp. 73-92
    • Serretti, A.1    Olgiati, P.2    De Ronchi, D.3
  • 329
    • 42649084052 scopus 로고    scopus 로고
    • The role of interleukin-1 in neuroinflammation and Alzheimer disease: An evolving perspective
    • Shaftel, S. S., Griffin, W. S., & O'Banion, M. K. (2008). The role of interleukin-1 in neuroinflammation and Alzheimer disease: An evolving perspective. Journal of Neuroinflammation, 5, 7.
    • (2008) Journal of Neuroinflammation , vol.5 , pp. 7
    • Shaftel, S.S.1    Griffin, W.S.2    O'Banion, M.K.3
  • 330
    • 0028341702 scopus 로고
    • Elevated interleukin-6 secretion levels by mononuclear cells of Alzheimer's patients
    • DOI 10.1016/0304-3940(94)90003-5
    • Shalit, F., Sredni, B., Stern, L., Kott, E., & Huberman, M. (1994). Elevated interleukin-6 secretion levels by mononuclear cells of Alzheimer's patients. Neuroscience Letters, 174, 130-132. (Pubitemid 24199480)
    • (1994) Neuroscience Letters , vol.174 , Issue.2 , pp. 130-132
    • Shalit, F.1    Sredni, B.2    Stern, L.3    Kott, E.4    Huberman, M.5
  • 331
    • 0030725725 scopus 로고    scopus 로고
    • Astrocyte-apolipoprotein E associations in senile plaques in Alzheimer disease and vascular lesions: A regional immunohistochemical study
    • Shao, Y., Gearing, M., & Mirra, S. S. (1997). Astrocyte- apolipoprotein E associations in senile plaques in Alzheimer disease and vascular lesions: A regional immunohistochemical study. Journal of Neuropathology and Experimental Neurology, 56, 376-381. (Pubitemid 27465020)
    • (1997) Journal of Neuropathology and Experimental Neurology , vol.56 , Issue.4 , pp. 376-381
    • Shao, Y.1    Gearing, M.2    Mirra, S.S.3
  • 333
    • 64449083752 scopus 로고    scopus 로고
    • Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease
    • Sheng, B., Gong, K., Niu, Y., Liu, L., Yan, Y., Lu, G., et al. (2009). Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease. Free Radical Biology and Medicine, 46, 1362-1375.
    • (2009) Free Radical Biology and Medicine , vol.46 , pp. 1362-1375
    • Sheng, B.1    Gong, K.2    Niu, Y.3    Liu, L.4    Yan, Y.5    Lu, G.6
  • 334
    • 0030778215 scopus 로고    scopus 로고
    • + astrocytes with neurofibrillary tangle stages
    • Sheng, J. G., Mrak, R. E., & Griffin, W. S. (1997). Glial-neuronal interactions in Alzheimer disease: Progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages. Journal of Neuropathology and Experimental Neurology, 56, 285-290. (Pubitemid 27461169)
    • (1997) Journal of Neuropathology and Experimental Neurology , vol.56 , Issue.3 , pp. 285-290
    • Sheng, J.G.1    Mrak, R.E.2    Griffin, W.S.T.3
  • 335
    • 37349049243 scopus 로고    scopus 로고
    • Oxidative stress and transcriptional regulation in Alzheimer disease
    • DOI 10.1097/WAD.0b013e31815721c3, PII 0000209320071000000004
    • Shi, Q., & Gibson, G. E. (2007). Oxidative stress and transcriptional regulation in Alzheimer disease. Alzheimer Disease and Associated Disorders, 21, 276-291. (Pubitemid 350307432)
    • (2007) Alzheimer Disease and Associated Disorders , vol.21 , Issue.4 , pp. 276-291
    • Shi, Q.1    Gibson, G.E.2
  • 336
    • 14644444518 scopus 로고    scopus 로고
    • Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2004.09.004
    • Shibata, N., Ohnuma, T., Higashi, S., Usui, C., Ohkubo, T., Kitajima, A., et al. (2005). Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease. Neurobiology of Aging, 26, 1011-1014. (Pubitemid 40312664)
    • (2005) Neurobiology of Aging , vol.26 , Issue.7 , pp. 1011-1014
    • Shibata, N.1    Ohnuma, T.2    Higashi, S.3    Usui, C.4    Ohkubo, T.5    Kitajima, A.6    Ueki, A.7    Nagao, M.8    Arai, H.9
  • 337
    • 0032458543 scopus 로고    scopus 로고
    • Intracellular receptors for activated C-kinase in the postmortem human brain: No alteration in Alzheimer disease
    • Shimohama, S., Kamiya, S., Taniguchi, T., & Kimura, J. (1998). Intracellular receptors for activated C-kinase in the postmortem human brain: No alteration in Alzheimer disease. Alzheimer Disease and Associated Disorders, 12, 384-386. (Pubitemid 29050756)
    • (1998) Alzheimer Disease and Associated Disorders , vol.12 , Issue.4 , pp. 384-386
    • Shimohama, S.1    Kamiya, S.2    Taniguchi, T.3    Kimura, J.4
  • 338
    • 80052689551 scopus 로고    scopus 로고
    • Fluorescent analysis of the cell-selective Alzheimer's disease Abeta peptide surface membrane binding: Influence of membrane components
    • doi:10.4061/2011/917629
    • Simakova, O., & Arispe, N. J. (2011). Fluorescent analysis of the cell-selective Alzheimer's disease Abeta peptide surface membrane binding: Influence of membrane components. International Journal of Alzheimer's Disease. doi:10.4061/2011/917629.
    • (2011) International Journal of Alzheimer's Disease
    • Simakova, O.1    Arispe, N.J.2
  • 339
    • 34547624611 scopus 로고    scopus 로고
    • Supply and demand in cerebral energy metabolism: The role of nutrient transporters
    • DOI 10.1038/sj.jcbfm.9600521, PII 9600521
    • Simpson, I. A., Carruthers, A., & Vannucci, S. J. (2007). Supply and demand in cerebral energy metabolism: The role of nutrient transporters. Journal of Cerebral Blood Flow and Metabolism, 27, 1766-1791. (Pubitemid 47624552)
    • (2007) Journal of Cerebral Blood Flow and Metabolism , vol.27 , Issue.11 , pp. 1766-1791
    • Simpson, I.A.1    Carruthers, A.2    Vannucci, S.J.3
  • 340
    • 73949134382 scopus 로고    scopus 로고
    • Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain
    • Simpson, J. E., Ince, P. G., Haynes, L. J., Theaker, R., Gelsthorpe, C., Baxter, L., et al. (2010a). Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain. Neuropathology and Applied Neurobiology, 36, 25-40.
    • (2010) Neuropathology and Applied Neurobiology , vol.36 , pp. 25-40
    • Simpson, J.E.1    Ince, P.G.2    Haynes, L.J.3    Theaker, R.4    Gelsthorpe, C.5    Baxter, L.6
  • 341
  • 342
    • 77957256030 scopus 로고    scopus 로고
    • Role of by-products of lipid oxidation in Alzheimer's disease brain: A focus on acrolein
    • Singh, M., Nam, D. T., Arseneault, M., & Ramassamy, C. (2010). Role of by-products of lipid oxidation in Alzheimer's disease brain: A focus on acrolein. Journal of Alzheimer's Disease, 21, 741-756.
    • (2010) Journal of Alzheimer's Disease , vol.21 , pp. 741-756
    • Singh, M.1    Nam, D.T.2    Arseneault, M.3    Ramassamy, C.4
  • 343
    • 0028985799 scopus 로고
    • Role of the beta-amyloid protein in Alzheimer's disease
    • Sisodia, S. S., & Price, D. L. (1995). Role of the beta-amyloid protein in Alzheimer's disease. FASEB J, 9, 366-370.
    • (1995) FASEB J , vol.9 , pp. 366-370
    • Sisodia, S.S.1    Price, D.L.2
  • 344
    • 3342945136 scopus 로고    scopus 로고
    • Elevated serum levels of the apoptosis related molecules TNF-α, Fas/Apo-1 and Bcl-2 in oral lichen planus
    • DOI 10.1111/j.1600-0714.2004.00221.x
    • Sklavounou-Andrikopoulou, A., Chrysomali, E., Iakovou, M., Garinis, G. A., & Karameris, A. (2004). Elevated serum levels of the apoptosis related molecules TNF-alpha, Fas/Apo-1 and Bcl-2 in oral lichen planus. Journal of Oral Pathology and Medicine, 33, 386-390. (Pubitemid 38988192)
    • (2004) Journal of Oral Pathology and Medicine , vol.33 , Issue.7 , pp. 386-390
    • Sklavounou-Andrikopoulou, A.1    Chrysomali, E.2    Iakovou, M.3    Garinis, G.A.4    Karameris, A.5
  • 346
    • 34547147090 scopus 로고    scopus 로고
    • The redox chemistry of the Alzheimer's disease amyloid βpeptide
    • DOI 10.1016/j.bbamem.2007.02.002, PII S0005273607000387
    • Smith, D. G., Cappai, R., & Barnham, K. J. (2007). The redox chemistry of the Alzheimer's disease amyloid beta peptide. Biochimica et Biophysica Acta, 1768, 1976-1990. (Pubitemid 47125850)
    • (2007) Biochimica et Biophysica Acta - Biomembranes , vol.1768 , Issue.8 , pp. 1976-1990
    • Smith, D.G.1    Cappai, R.2    Barnham, K.J.3
  • 348
    • 0028170846 scopus 로고
    • Glutamate, beta-amyloid precursor proteins, and calcium mediated neurofibrillary degeneration
    • Smith-Swintosky, V. L., & Mattson, M. P. (1994). Glutamate, beta-amyloid precursor proteins, and calcium mediated neurofibrillary degeneration. Journal of Neural Transmission. Supplementum, 44, 29-45. (Pubitemid 24372886)
    • (1994) Journal of Neural Transmission, Supplement , Issue.44 , pp. 29-45
    • Smith-Swintosky, V.L.1    Mattson, M.P.2
  • 349
    • 66949146836 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease
    • Sokolova, A., Hill, M. D., Rahimi, F., Warden, L. A., Halliday, G. M., & Shepherd, C. E. (2009). Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease. Brain Pathology, 19, 392-398.
    • (2009) Brain Pathology , vol.19 , pp. 392-398
    • Sokolova, A.1    Hill, M.D.2    Rahimi, F.3    Warden, L.A.4    Halliday, G.M.5    Shepherd, C.E.6
  • 351
    • 0034881033 scopus 로고    scopus 로고
    • Oxidative stress and protein aggregation during biological aging
    • DOI 10.1016/S0531-5565(01)00139-5, PII S0531556501001395
    • Squier, T. C. (2001). Oxidative stress and protein aggregation during biological aging. Experimental Gerontology, 36, 1539-1550. (Pubitemid 32768730)
    • (2001) Experimental Gerontology , vol.36 , Issue.9 , pp. 1539-1550
    • Squier, T.C.1
  • 353
    • 33645830313 scopus 로고    scopus 로고
    • Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease
    • Standridge, J. B. (2006). Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease. Current Alzheimer Research, 3, 95-108.
    • (2006) Current Alzheimer Research , vol.3 , pp. 95-108
    • Standridge, J.B.1
  • 355
    • 0035693363 scopus 로고    scopus 로고
    • Chemokines and Alzheimer's disease
    • DOI 10.1016/S0197-4580(01)00290-1, PII S0197458001002901
    • Streit, W. J., Conde, J. R., & Harrison, J. K. (2001). Chemokines and Alzheimer's disease. Neurobiology of Aging, 22, 909-913. (Pubitemid 34066558)
    • (2001) Neurobiology of Aging , vol.22 , Issue.6 , pp. 909-913
    • Streit, W.J.1    Conde, J.R.2    Harrison, J.K.3
  • 356
    • 77049106382 scopus 로고    scopus 로고
    • Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy
    • Strongin, A. Y. (2010). Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy. Biochimica et Biophysica Acta, 1803, 133-141.
    • (2010) Biochimica et Biophysica Acta , vol.1803 , pp. 133-141
    • Strongin, A.Y.1
  • 357
    • 37149006484 scopus 로고    scopus 로고
    • Alterations of some membrane transport proteins in Alzheimer's disease: Role of amyloid beta-peptide
    • Sultana, R., & Butterfield, D. A. (2008). Alterations of some membrane transport proteins in Alzheimer's disease: Role of amyloid beta-peptide. Molecular BioSystems, 4, 36-41.
    • (2008) Molecular BioSystems , vol.4 , pp. 36-41
    • Sultana, R.1    Butterfield, D.A.2
  • 358
    • 70449411818 scopus 로고    scopus 로고
    • Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment
    • Sultana, R., & Butterfield, D. A. (2009). Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment. Journal of Bioenergetics and Biomembranes, 41, 441-446.
    • (2009) Journal of Bioenergetics and Biomembranes , vol.41 , pp. 441-446
    • Sultana, R.1    Butterfield, D.A.2
  • 359
    • 2442457913 scopus 로고    scopus 로고
    • Protective effect of the xanthate, D609, on Alzheimer's amyloid β-peptide (1-42)-induced oxidative stress in primary neuronal cells
    • DOI 10.1080/1071576042000206478
    • Sultana, R., Newman, S., Mohmmad-Abdul, H., Keller, J. N., & Butterfield, D. A. (2004). Protective effect of the xanthate, D609, on Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress in primary neuronal cells. Free Radical Research, 38, 449-458. (Pubitemid 38618366)
    • (2004) Free Radical Research , vol.38 , Issue.5 , pp. 449-458
    • Sultana, R.1    Newman, S.2    Mohmmad-Abdul, H.3    Keller, J.N.4    Butterfield, D.A.5
  • 360
    • 33645089917 scopus 로고    scopus 로고
    • Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach
    • Sultana, R., Poon, H. F., Cai, J., Pierce, W. M., Merchant, M., Klein, J. B., et al. (2006). Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiology of Diseases, 22, 76-87.
    • (2006) Neurobiology of Diseases , vol.22 , pp. 76-87
    • Sultana, R.1    Poon, H.F.2    Cai, J.3    Pierce, W.M.4    Merchant, M.5    Klein, J.B.6
  • 362
    • 9644275598 scopus 로고    scopus 로고
    • Modulation of nuclear factor-κB activity by indomethacin influences Aβ levels but not Aβ precursor protein metabolism in a model of Alzheimer's disease
    • Sung, S., Yang, H., Uryu, K., Lee, E. B., Zhao, L., Shineman, D., et al. (2004). Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. American Journal of Pathology, 165, 2197-2206. (Pubitemid 39578396)
    • (2004) American Journal of Pathology , vol.165 , Issue.6 , pp. 2197-2206
    • Sung, S.1    Yang, H.2    Uryu, K.3    Lee, E.B.4    Zhao, L.5    Shineman, D.6    Trojanowski, J.Q.7    Lee, V.M.-Y.8    Pratico, D.9
  • 363
    • 0035255055 scopus 로고    scopus 로고
    • IL-4, IL-10 and IL-13 modulate Aβ(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
    • DOI 10.1016/S0165-5728(00)00404-5, PII S0165572800004045
    • Szczepanik, A. M., Funes, S., Petko, W., & Ringheim, G. E. (2001a). IL-4, IL-10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line. Journal of Neuroimmunology, 113, 49-62. (Pubitemid 32008670)
    • (2001) Journal of Neuroimmunology , vol.113 , Issue.1 , pp. 49-62
    • Szczepanik, A.M.1    Funes, S.2    Petko, W.3    Ringheim, G.E.4
  • 364
    • 0035085610 scopus 로고    scopus 로고
    • Amyloid-β peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo
    • DOI 10.1046/j.1471-4159.2001.00240.x
    • Szczepanik, A. M., Rampe, D., & Ringheim, G. E. (2001b). Amyloidbeta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. Journal of Neurochemistry, 77, 304-317. (Pubitemid 32245104)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.1 , pp. 304-317
    • Szczepanik, A.M.1    Rampe, D.2    Ringheim, G.E.3
  • 365
    • 38049098793 scopus 로고    scopus 로고
    • Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein
    • Tamagno, E., Guglielmotto, M., Aragno, M., Borghi, R., Autelli, R., Giliberto, L., et al. (2008). Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. Journal of Neurochemistry, 104, 683-695.
    • (2008) Journal of Neurochemistry , vol.104 , pp. 683-695
    • Tamagno, E.1    Guglielmotto, M.2    Aragno, M.3    Borghi, R.4    Autelli, R.5    Giliberto, L.6
  • 367
    • 67049171648 scopus 로고    scopus 로고
    • Neuronal protein trafficking associated with Alzheimer disease: From APP and BACE1 to glutamate receptors
    • Tang, B. L. (2009). Neuronal protein trafficking associated with Alzheimer disease: From APP and BACE1 to glutamate receptors. Cell Adhesion & Migration, 3, 118-128.
    • (2009) Cell Adhesion & Migration , vol.3 , pp. 118-128
    • Tang, B.L.1
  • 368
    • 0032868874 scopus 로고    scopus 로고
    • Intracerebral production of tumor necrosis factor-α, a local neuroprotective agent, in Alzheimer disease and vascular dementia
    • DOI 10.1023/A:1020568013953
    • Tarkowski, E., Blennow, K., Wallin, A., & Tarkowski, A. (1999). Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia. Journal of Clinical Immunology, 19, 223-230. (Pubitemid 29409451)
    • (1999) Journal of Clinical Immunology , vol.19 , Issue.4 , pp. 223-230
    • Tarkowski, E.1    Blennow, K.2    Wallin, A.3    Tarkowski, A.4
  • 369
    • 0030607145 scopus 로고    scopus 로고
    • Enhancement of immunoreactivity for NF-κB in the hippocampal formation and cerebral cortex of Alzheimer's disease
    • DOI 10.1016/0006-8993(96)00310-1
    • Terai, K., Matsuo, A., & McGeer, P. L. (1996). Enhancement of immunoreactivity for NF-kappa B in the hippocampal formation and cerebral cortex of Alzheimer's disease. Brain Research, 735, 159-168. (Pubitemid 26336632)
    • (1996) Brain Research , vol.735 , Issue.1 , pp. 159-168
    • Terai, K.1    Matsuo, A.2    McGeer, P.L.3
  • 370
  • 371
    • 77952429592 scopus 로고    scopus 로고
    • Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiency
    • Tibolla, G., Norata, G. D., Meda, C., Arnaboldi, L., Uboldi, P., Piazza, F., et al. (2010). Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiency. Atherosclerosis, 210, 78-87.
    • (2010) Atherosclerosis , vol.210 , pp. 78-87
    • Tibolla, G.1    Norata, G.D.2    Meda, C.3    Arnaboldi, L.4    Uboldi, P.5    Piazza, F.6
  • 372
    • 34547435817 scopus 로고    scopus 로고
    • Neuroinflammation and regulation of glial glutamate uptake in neurological disorders
    • DOI 10.1002/jnr.21325
    • Tilleux, S., & Hermans, E. (2007). Neuroinflammation and regulation of glial glutamate uptake in neurological disorders. Journal of Neuroscience Research, 85, 2059-2070. (Pubitemid 47172138)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.10 , pp. 2059-2070
    • Tilleux, S.1    Hermans, E.2
  • 373
    • 0028101778 scopus 로고
    • Characteristic transketolase alterations in dermal fibroblasts of Alzheimer patients are modulated by culture conditions
    • DOI 10.1006/exmp.1994.1013
    • Tombaccini, D., Mocali, A., & Paoletti, F. (1994). Characteristic transketolase alterations in dermal fibroblasts of Alzheimer patients are modulated by culture conditions. Experimental and Molecular Pathology, 60, 140-146. (Pubitemid 24287210)
    • (1994) Experimental and Molecular Pathology , vol.60 , Issue.2 , pp. 140-146
    • Tombaccini, D.1    Mocali, A.2    Paoletti, F.3
  • 374
    • 34447650944 scopus 로고    scopus 로고
    • Expression of macrophage inflammatory protein 1-α is elevated in Alzheimer's vessels and is regulated by oxidative stress
    • Tripathy, D., Thirumangalakudi, L., & Grammas, P. (2007). Expression of macrophage inflammatory protein 1-alpha is elevated in Alzheimer's vessels and is regulated by oxidative stress. Journal of Alzheimer's Disease, 11, 447-455. (Pubitemid 47094015)
    • (2007) Journal of Alzheimer's Disease , vol.11 , Issue.4 , pp. 447-455
    • Tripathy, D.1    Thirumangalakudi, L.2    Grammas, P.3
  • 375
    • 0024453786 scopus 로고
    • The astrocyte-endothelial interface in cerebellar astrocytoma
    • Uematsu, Y., Hirano, A., Kawano, H., & Llena, J. F. (1989). The astrocyte-endothelial interface in cerebellar astrocytoma. No Shinkei Geka, 17, 999-1004. (Pubitemid 19279598)
    • (1989) Neurological Surgery , vol.17 , Issue.11 , pp. 999-1004
    • Uematsu, Y.1    Hirano, A.2    Kawano, H.3    Llena, J.F.4
  • 376
    • 0037038816 scopus 로고    scopus 로고
    • β-secretase (BACE) as a drug target for Alzheimer's disease
    • DOI 10.1016/S0169-409X(02)00157-6, PII S0169409X02001576
    • Vassar, R. (2002). Beta-secretase (BACE) as a drug target for Alzheimer's disease. Advanced Drug Delivery Reviews, 54, 1589-1602. (Pubitemid 35346833)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.12 , pp. 1589-1602
    • Vassar, R.1
  • 377
    • 4344630985 scopus 로고    scopus 로고
    • BACE1: The beta-secretase enzyme in Alzheimer's disease
    • Vassar, R. (2004). BACE1: The beta-secretase enzyme in Alzheimer's disease. Journal of Molecular Neuroscience, 23, 105-114.
    • (2004) Journal of Molecular Neuroscience , vol.23 , pp. 105-114
    • Vassar, R.1
  • 378
    • 0033595706 scopus 로고    scopus 로고
    • Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., et al. (1999). Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science, 286, 735-741.
    • (1999) Science , vol.286 , pp. 735-741
    • Vassar, R.1    Bennett, B.D.2    Babu-Khan, S.3    Kahn, S.4    Mendiaz, E.A.5    Denis, P.6
  • 381
    • 0025041392 scopus 로고
    • Involvement of free radicals in dementia of the Alzheimer type: A hypothesis
    • DOI 10.1016/0197-4580(90)90119-K
    • Volicer, L., & Crino, P. B. (1990). Involvement of free radicals in dementia of the Alzheimer type: A hypothesis. Neurobiology of Aging, 11, 567-571. (Pubitemid 20297151)
    • (1990) Neurobiology of Aging , vol.11 , Issue.5 , pp. 567-571
    • Volicer, L.1    Crino, P.B.2
  • 382
    • 78650685650 scopus 로고    scopus 로고
    • Beta-amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease
    • Wan, L., Nie, G., Zhang, J., Luo, Y., Zhang, P., Zhang, Z., et al. (2011). Beta-amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease. Free Radical Biology and Medicine, 50, 122-129.
    • (2011) Free Radical Biology and Medicine , vol.50 , pp. 122-129
    • Wan, L.1    Nie, G.2    Zhang, J.3    Luo, Y.4    Zhang, P.5    Zhang, Z.6
  • 383
    • 77955918642 scopus 로고    scopus 로고
    • The interleukin-6 gene-572C/G promoter polymorphism modifies Alzheimer's risk in APOE epsilon 4 carriers
    • Wang, M., & Jia, J. (2010). The interleukin-6 gene-572C/G promoter polymorphism modifies Alzheimer's risk in APOE epsilon 4 carriers. Neuroscience Letters, 482, 260-263.
    • (2010) Neuroscience Letters , vol.482 , pp. 260-263
    • Wang, M.1    Jia, J.2
  • 385
    • 0028981561 scopus 로고
    • Neurotoxicity of A beta amyloid protein in vitro is not altered by calcium channel blockade
    • Whitson, J. S., & Appel, S. H. (1995). Neurotoxicity of A beta amyloid protein in vitro is not altered by calcium channel blockade. Neurobiology of Aging, 16, 5-10.
    • (1995) Neurobiology of Aging , vol.16 , pp. 5-10
    • Whitson, J.S.1    Appel, S.H.2
  • 386
    • 0028244469 scopus 로고
    • Activation of adult human derived microglia by myelin phagocytosis in vitro
    • DOI 10.1002/jnr.490380409
    • Williams, K., Ulvestad, E., Waage, A., Antel, J. P., & McLaurin, J. (1994). Activation of adult human derived microglia by myelin phagocytosis in vitro. Journal of Neuroscience Research, 38, 433-443. (Pubitemid 24209433)
    • (1994) Journal of Neuroscience Research , vol.38 , Issue.4 , pp. 433-443
    • Williams, K.1    Ulvestad, E.2    Waage, A.3    Antel, J.P.4    McLaurin, J.5
  • 387
    • 78751671052 scopus 로고    scopus 로고
    • Sources of variability in estimates of the prevalence of Alzheimer's disease in the United States
    • Wilson, R. S., Weir, D. R., Leurgans, S. E., Evans, D. A., Hebert, L. E., Langa, K. M., et al. (2011). Sources of variability in estimates of the prevalence of Alzheimer's disease in the United States. Alzheimers Dementia, 7, 74-79.
    • (2011) Alzheimers Dementia , vol.7 , pp. 74-79
    • Wilson, R.S.1    Weir, D.R.2    Leurgans, S.E.3    Evans, D.A.4    Hebert, L.E.5    Langa, K.M.6
  • 388
    • 0035976590 scopus 로고    scopus 로고
    • Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease
    • DOI 10.1016/S0006-8993(01)02872-4, PII S0006899301028724
    • Wong, A., Luth, H. J., Deuther-Conrad, W., Dukic-Stefanovic, S., Gasic-Milenkovic, J., Arendt, T., et al. (2001). Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease. Brain Research, 920, 32-40. (Pubitemid 33086777)
    • (2001) Brain Research , vol.920 , Issue.1-2 , pp. 32-40
    • Wong, A.1    Luth, H.-J.2    Deuther-Conrad, W.3    Dukic-Stefanovic, S.4    Gasic-Milenkovic, J.5    Arendt, T.6    Munch, G.7
  • 389
    • 0032572973 scopus 로고    scopus 로고
    • Programmed cell death
    • DOI 10.1097/00007890-199809270-00001
    • Woodle, E. S., & Kulkarni, S. (1998). Programmed cell death. Transplantation, 66, 681-691. (Pubitemid 28460101)
    • (1998) Transplantation , vol.66 , Issue.6 , pp. 681-691
    • Woodle, E.S.1    Kulkarni, S.2
  • 390
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: Driving force, bystander or beneficial response?
    • DOI 10.1038/nm1484, PII NM1484
    • Wyss-Coray, T. (2006). Inflammation in Alzheimer disease: Driving force, bystander or beneficial response? Nature Medicine, 12, 1005-1015. (Pubitemid 44353380)
    • (2006) Nature Medicine , vol.12 , Issue.9 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 391
    • 0032917904 scopus 로고    scopus 로고
    • Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
    • Xia, M. Q., & Hyman, B. T. (1999). Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. Journal of Neurovirology, 5, 32-41. (Pubitemid 29051876)
    • (1999) Journal of NeuroVirology , vol.5 , Issue.1 , pp. 32-41
    • Xia, M.1    Hyman, B.T.2
  • 392
    • 0031848322 scopus 로고    scopus 로고
    • Immunohistochemical study of the β-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains
    • Xia, M. Q., Qin, S. X., Wu, L. J., Mackay, C. R., & Hyman, B. T. (1998). Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains. American Journal of Pathology, 153, 31-37. (Pubitemid 28317504)
    • (1998) American Journal of Pathology , vol.153 , Issue.1 , pp. 31-37
    • Xia, M.1    Qin, S.2    Wu, L.3    Mackay, C.R.4    Hyman, B.T.5
  • 393
    • 33947512432 scopus 로고    scopus 로고
    • Interferon-γ and tumor necrosis factor-α regulate amyloid-β plaque deposition and β-secretase expression in Swedish mutant APP transgenic mice
    • DOI 10.2353/ajpath.2007.060378
    • Yamamoto, M., Kiyota, T., Horiba, M., Buescher, J. L., Walsh, S. M., Gendelman, H. E., et al. (2007). Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice. American Journal of Pathology, 170, 680-692. (Pubitemid 47339404)
    • (2007) American Journal of Pathology , vol.170 , Issue.2 , pp. 680-692
    • Yamamoto, M.1    Kiyota, T.2    Horiba, M.3    Buescher, J.L.4    Walsh, S.M.5    Gendelman, H.E.6    Ikezu, T.7
  • 394
    • 67649739088 scopus 로고    scopus 로고
    • RAGE and Alzheimer's disease: A progression factor for amyloid-beta-induced cellular perturbation?
    • Yan, S. D., Bierhaus, A., Nawroth, P. P., & Stern, D. M. (2009). RAGE and Alzheimer's disease: A progression factor for amyloid-beta-induced cellular perturbation? Journal of Alzheimer's Disease, 16, 833-843.
    • (2009) Journal of Alzheimer's Disease , vol.16 , pp. 833-843
    • Yan, S.D.1    Bierhaus, A.2    Nawroth, P.P.3    Stern, D.M.4
  • 395
    • 0034986151 scopus 로고    scopus 로고
    • Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid
    • Yan, J. J., Cho, J. Y., Kim, H. S., Kim, K. L., Jung, J. S., Huh, S. O., et al. (2001). Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid. British Journal of Pharmacology, 133, 89-96.
    • (2001) British Journal of Pharmacology , vol.133 , pp. 89-96
    • Yan, J.J.1    Cho, J.Y.2    Kim, H.S.3    Kim, K.L.4    Jung, J.S.5    Huh, S.O.6
  • 396
    • 54149084726 scopus 로고    scopus 로고
    • Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia
    • Yan, F. L., Zheng, Y., & Zhao, F. D. (2008). Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia. Acta Neuropathologica, 116, 529-535.
    • (2008) Acta Neuropathologica , vol.116 , pp. 529-535
    • Yan, F.L.1    Zheng, Y.2    Zhao, F.D.3
  • 397
    • 0032544526 scopus 로고    scopus 로고
    • Upregulation of amyloid precursor protein gene promoter in rat primary hippocampal neurons by phorbol ester, IL-1 and retinoic acid, but not by reactive oxygen species
    • DOI 10.1016/S0169-328X(98)00164-8, PII S0169328X98001648
    • Yang, Y., Quitschke, W. W., & Brewer, G. J. (1998a). Upregulation of amyloid precursor protein gene promoter in rat primary hippocampal neurons by phorbol ester, IL-1 and retinoic acid, but not by reactive oxygen species. Brain Research. Molecular Brain Research, 60, 40-49. (Pubitemid 28433193)
    • (1998) Molecular Brain Research , vol.60 , Issue.1 , pp. 40-49
    • Yang, Y.1    Quitschke, W.W.2    Brewer, G.J.3
  • 398
    • 0031930313 scopus 로고    scopus 로고
    • Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease
    • Yang, F., Sun, X., Beech, W., Teter, B., Wu, S., Sigel, J., et al. (1998b). Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. American Journal of Pathology, 152, 379-389. (Pubitemid 28106384)
    • (1998) American Journal of Pathology , vol.152 , Issue.2 , pp. 379-389
    • Yang, F.1    Sun, X.2    Beech, W.3    Teter, B.4    Wu, S.5    Sigel, J.6    Vinters, H.V.7    Frautschy, S.A.8    Cole, G.M.9
  • 399
    • 18044392303 scopus 로고    scopus 로고
    • Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis
    • Yao, Y., Chinnici, C., Tang, H., Trojanowski, J. Q., Lee, V. M., & Pratico, D. (2004). Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis. Journal of Neuroinflammation, 1, 21.
    • (2004) Journal of Neuroinflammation , vol.1 , pp. 21
    • Yao, Y.1    Chinnici, C.2    Tang, H.3    Trojanowski, J.Q.4    Lee, V.M.5    Pratico, D.6
  • 400
    • 0033133579 scopus 로고    scopus 로고
    • In vitro and in vivo oxidative stress associated with Alzheimer's amyloid β-peptide (1-42)
    • DOI 10.1016/S0197-4580(99)00056-1, PII S0197458099000561
    • Yatin, S. M., Varadarajan, S., Link, C. D., & Butterfield, D. A. (1999). In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta-peptide (1-42). Neurobiology of Aging, 20, 325-330 (discussion 339-342). (Pubitemid 29525418)
    • (1999) Neurobiology of Aging , vol.20 , Issue.3 , pp. 325-330
    • Yatin, S.M.1    Varadarajan, S.2    Link, C.D.3    Butterfield, D.A.4
  • 401
    • 0033950591 scopus 로고    scopus 로고
    • Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain
    • Yoshiyama, Y., Asahina, M., & Hattori, T. (2000). Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain. Acta Neuropathologica, 99, 91-95. (Pubitemid 30093413)
    • (2000) Acta Neuropathologica , vol.99 , Issue.2 , pp. 91-95
    • Yoshiyama, Y.1    Asahina, M.2    Hattori, T.3
  • 402
    • 77952048948 scopus 로고    scopus 로고
    • Evidence for the involvement of apoptosis-inducing factor-mediated caspase-independent neuronal death in Alzheimer disease
    • Yu, W., Mechawar, N., Krantic, S., & Quirion, R. (2010). Evidence for the involvement of apoptosis-inducing factor-mediated caspase-independent neuronal death in Alzheimer disease. American Journal of Pathology, 176, 2209-2218.
    • (2010) American Journal of Pathology , vol.176 , pp. 2209-2218
    • Yu, W.1    Mechawar, N.2    Krantic, S.3    Quirion, R.4
  • 403
    • 58149101483 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases
    • Zhang, L., Bukulin, M., Kojro, E., Roth, A., Metz, V. V., Fahrenholz, F., et al. (2008). Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases. The Journal of Biological Chemistry, 283, 35507-35516.
    • (2008) The Journal of Biological Chemistry , vol.283 , pp. 35507-35516
    • Zhang, L.1    Bukulin, M.2    Kojro, E.3    Roth, A.4    Metz, V.V.5    Fahrenholz, F.6
  • 404
    • 67349092442 scopus 로고    scopus 로고
    • Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice
    • Zhang, X., Luhrs, K. J., Ryff, K. A., Malik, W. T., Driscoll, M. J., & Culver, B. (2009). Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice. Neuroscience, 161, 53-58.
    • (2009) Neuroscience , vol.161 , pp. 53-58
    • Zhang, X.1    Luhrs, K.J.2    Ryff, K.A.3    Malik, W.T.4    Driscoll, M.J.5    Culver, B.6
  • 405
    • 78349309457 scopus 로고    scopus 로고
    • Angiotensin II induced cerebral microvascular inflammation and increased blood-brain barrier permeability via oxidative stress
    • Zhang, M., Mao, Y., Ramirez, S. H., Tuma, R. F., & Chabrashvili, T. (2010). Angiotensin II induced cerebral microvascular inflammation and increased blood-brain barrier permeability via oxidative stress. Neuroscience, 171, 852-858.
    • (2010) Neuroscience , vol.171 , pp. 852-858
    • Zhang, M.1    Mao, Y.2    Ramirez, S.H.3    Tuma, R.F.4    Chabrashvili, T.5
  • 407
    • 0037289757 scopus 로고    scopus 로고
    • The induction of the TNFα death domain signaling pathway in Alzheimer's disease brain
    • DOI 10.1023/A:1022337519035
    • Zhao, M., Cribbs, D. H., Anderson, A. J., Cummings, B. J., Su, J. H., Wasserman, A. J., et al. (2003). The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain. Neurochemical Research, 28, 307-318. (Pubitemid 36207354)
    • (2003) Neurochemical Research , vol.28 , Issue.2 , pp. 307-318
    • Zhao, M.1    Cribbs, D.H.2    Anderson, A.J.3    Cummings, B.J.4    Su, J.H.5    Wasserman, A.J.6    Cotman, C.W.7
  • 409
    • 0037629304 scopus 로고    scopus 로고
    • Inflammation and proinflammatory cytokine production, but no demyelination of facial nerves, in experimental autoimmune neuritis in Lewis rats
    • DOI 10.1016/S0165-5728(03)00178-4
    • Zhu, W., Mix, E., & Zhu, J. (2003). Inflammation and proinflammatory cytokine production, but no demyelination of facial nerves, in experimental autoimmune neuritis in Lewis rats. Journal of Neuroimmunology, 140, 97-101. (Pubitemid 36836094)
    • (2003) Journal of Neuroimmunology , vol.140 , Issue.1-2 , pp. 97-101
    • Zhu, W.1    Mix, E.2    Zhu, J.3
  • 410
    • 78149255128 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid beta-peptide elimination from the brain
    • Zlokovic, B. V., Deane, R., Sagare, A. P., Bell, R. D., & Winkler, E. A. (2010). Low-density lipoprotein receptor-related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid beta-peptide elimination from the brain. Journal of Neurochemistry, 115, 1077-1089.
    • (2010) Journal of Neurochemistry , vol.115 , pp. 1077-1089
    • Zlokovic, B.V.1    Deane, R.2    Sagare, A.P.3    Bell, R.D.4    Winkler, E.A.5
  • 411
    • 41549101387 scopus 로고    scopus 로고
    • Proteasome subunit proteins and neuropathology in tauopathies and synucleinopathies: Consequences for proteomic analyses
    • DOI 10.1002/pmic.200700679
    • Zouambia, M., Fischer, D. F., Hobo, B., De Vos, R. A., Hol, E. M., Varndell, I. M., et al. (2008). Proteasome subunit proteins and neuropathology in tauopathies and synucleinopathies: Consequences for proteomic analyses. Proteomics, 8, 1221-1236. (Pubitemid 351462928)
    • (2008) Proteomics , vol.8 , Issue.6 , pp. 1221-1236
    • Zouambia, M.1    Fischer, D.F.2    Hobo, B.3    De Vos, R.A.I.4    Hol, E.M.5    Varndell, I.M.6    Sheppard, P.W.7    Van Leeuwen, F.W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.