Interaction between matrix metalloproteinase 3 and the ε4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns

Neuroscience Letters

Volumn 367, Issue 3, 2004, Pages 336-339

  Saarela, Marika S ^a   Lehtimäki, Terho ^a   Rinne, Juha O ^b   Hervonen, Antti ^c   Jylhä, Marja ^c   Röyttä, Matias ^b   Ahonen, Jukka Pekka ^a,d   Mattila, Kari M ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF TAMPERE   (Finland)

^d TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Alzheimer's disease; Genotype; Matrix metalloproteinase; Parkinson's disease; Polymerase chain reaction; Polymorphism

Indexed keywords

APOLIPOPROTEIN E; STROMELYSIN;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN INTERACTION; RISK ASSESSMENT;

AGED; AGED, 80 AND OVER; ALANINE; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; FEMALE; FINLAND; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; ODDS RATIO; POLYMORPHISM, GENETIC; RISK;

EID: 4444360155     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.06.027     Document Type: Article

References (16)

1. Deb S., Gottschall P.E. Increased production of matrix metalloproteinases in enriched astrocyte and mixed hippocampal cultures treated with beta-amyloid peptides. J. Neurochem. 66:1996;1641-1647
2. Dunleavey L., Beyzade S., Ye S. Rapid genotype analysis of the matrix metalloproteinase-1 gene 1G/2G polymorphism that is associated with risk of cancer. Matrix Biol. 19:2000;175-177
3. Gnasso A., Motti C., Irace C., Carallo C., Liberatoscioli L., Bernardini S., Massoud R., Mattioli P.L., Federici G., Cortese C. Genetic variation in human stromelysin gene promoter and common carotid geometry in healthy male subjects. Arterioscler. Thromb. Vasc. Biol. 20:2000;1600-1605
4. Gottschall P.E., Deb S. Regulation of matrix metalloproteinase expressions in astrocytes. Neuroimmunomodulation. 3:1996;69-75
5. Hixson J.E., Vernier D.T. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J. Lipid Res. 31:1990;545-548
6. Leake A., Morris C.M., Whateley J. Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease. Neurosci. Lett. 291:2000;201-203
7. Lorenzl S., Albers D.S., LeWitt P.A., Chirichigno J.W., Hilgenberg S.L., Cudkowicz M.E., Beal M.F. Tissue inhibitors of matrix metalloproteinases are elevated in cerebrospinal fluid of neurodegenerative diseases. J. Neurol. Sci. 207:2003;71-76
8. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 34:1984;939-944
9. Mirra S.S., Heyman A., McKeel D., Sumi S.M., Crain B.J., Brownlee L.M., Vogel F.S., Hughes J.P., van Belle G., Berg L. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486
10. Peltonen L., Pekkarinen P., Aaltonen J. Messages from an isolate: lessons from the Finnish gene pool. Biol. Chem. Hoppe Seyler. 376:1995;697-704
11. Rebeck G.W., Reiter J.S., Strickland D.K., Hyman B.T. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron. 11:1993;575-580
12. Rutter J.L., Mitchell T.I., Buttice G., Meyers J., Gusella J.F., Ozelius L.J., Brinckerhoff C.E. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription. Cancer Res. 58:1998;5321-5325
13. Schmechel D.E., Saunders A.M., Strittmatter W.J., Crain B.J., Hulette C.M., Joo S.H., Pericak-Vance M.A., Goldgaber D., Roses A.D. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA. 90:1993;9649-9653
14. Ye S. Polymorphism in matrix metalloproteinase gene promoters: implication in regulation of gene expression and susceptibility of various diseases. Matrix Biol. 19:2000;623-629
15. Ye S., Eriksson P., Hamsten A., Kurkinen M., Humphries S.E., Henney A.M. Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression. J. Biol. Chem. 271:1996;13055-13060
16. Yoshiyama Y., Asahina M., Hattori T. Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain. Acta Neuropathol. (Berl.). 99:2000;91-95