Antioxidants attenuate hyperglycaemia-mediated brain endothelial cell dysfunction and blood-brain barrier hyperpermeability

Diabetes, Obesity and Metabolism

Volumn 11, Issue 5, 2009, Pages 480-490

  Allen, C L ^a   Bayraktutan, Ulvi ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Blood brain barrier; Endothelium; Hyperglycaemia; Oxidative stress; Vascular disease

Indexed keywords

ANTIOXIDANT; APOCYNIN; ASCORBIC ACID; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLUTATHIONE PEROXIDASE; INTERCELLULAR ADHESION MOLECULE 1; MANGANESE 5,10,15,20 TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN PENTACHLORIDE; MANGANESE 5,10,15,20 TETRAKIS(4 BENZOIC ACID)PORPHYRIN; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRITE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TIOPRONIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; COCULTURE; CONTROLLED STUDY; ELECTRIC RESISTANCE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MEMBRANE PERMEABILITY; MICROVASCULATURE; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY;

EID: 65449158394     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2008.00987.x     Document Type: Article

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