메뉴 건너뛰기




Volumn 148, Issue 1-2, 2004, Pages 162-171

Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines

Author keywords

Alzheimer's disease; IL 1 ; IL 4; IL 6; PBMC; TNF

Indexed keywords

CHOLINESTERASE INHIBITOR; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 10744222732     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2003.11.003     Document Type: Article
Times cited : (117)

References (47)
  • 1
    • 20244364226 scopus 로고    scopus 로고
    • Up-regulation of the inflammatory cytokines IFN-g and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice
    • Abbas N., Bednar I., Mix E., Marie S., Paterson D., Ljungberg A., Morris C. Up-regulation of the inflammatory cytokines IFN-g and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice. J. Neuroimmunol. 126:2002;50-57.
    • (2002) J. Neuroimmunol. , vol.126 , pp. 50-57
    • Abbas, N.1    Bednar, I.2    Mix, E.3    Marie, S.4    Paterson, D.5    Ljungberg, A.6    Morris, C.7
  • 2
    • 0026638409 scopus 로고
    • Inflammatory cytokines within the central nervous system: Source, function, and mechanism of action
    • Benveniste E.N. Inflammatory cytokines within the central nervous system: source, function, and mechanism of action. Am. J. Physiol. 363:1992;C1-C16.
    • (1992) Am. J. Physiol. , vol.363
    • Benveniste, E.N.1
  • 5
    • 0027197996 scopus 로고
    • Neuroprotective role of IL-4 against activated microglia
    • Chao C.C., Molitor T.W., Hu S. Neuroprotective role of IL-4 against activated microglia. J. Immunol. 151:1993;1473-1481.
    • (1993) J. Immunol. , vol.151 , pp. 1473-1481
    • Chao, C.C.1    Molitor, T.W.2    Hu, S.3
  • 6
    • 0029620390 scopus 로고
    • Interleukin-1 and tumour necrosis factor-alpha synergistically mediate neurotoxicity: Involvement of nitric oxide and of N-methyl-D-aspartate receptors
    • Chao C.C., Hu S., Ehrlich L., Peterson P.K. Interleukin-1 and tumour necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors. Brain Behav. Immun. 9:1995;355-365.
    • (1995) Brain Behav. Immun. , vol.9 , pp. 355-365
    • Chao, C.C.1    Hu, S.2    Ehrlich, L.3    Peterson, P.K.4
  • 7
    • 0025015691 scopus 로고
    • Interleukin-4 and interleukin-1 receptor antagonist down-regulate interleukin-1 and tumour necrosis factor (TNF) generation in macrophages
    • Conti P., Dempsey R.A. Interleukin-4 and interleukin-1 receptor antagonist down-regulate interleukin-1 and tumour necrosis factor (TNF) generation in macrophages. Int. J. Immunopathol. Pharmacol. 2:1990;I-II.
    • (1990) Int. J. Immunopathol. Pharmacol. , vol.2
    • Conti, P.1    Dempsey, R.A.2
  • 8
    • 0028946146 scopus 로고
    • Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures
    • Del Bo R., Angeretti N., Lucca E., De Simoni M.G., Forloni G. Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures. Neurosci. Lett. 188:1995;70-74.
    • (1995) Neurosci. Lett. , vol.188 , pp. 70-74
    • Del Bo, R.1    Angeretti, N.2    Lucca, E.3    De Simoni, M.G.4    Forloni, G.5
  • 10
    • 0031471921 scopus 로고    scopus 로고
    • Role of pro- and anti-inflammatory cytokines during inflammation: Experimental and clinical findings
    • Dinarello C.A. Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings. J. Biol. Regul. Homeost. Agents. 11:1997;91-103.
    • (1997) J. Biol. Regul. Homeost. Agents , vol.11 , pp. 91-103
    • Dinarello, C.A.1
  • 11
    • 0032981238 scopus 로고    scopus 로고
    • Unchanged levels of interleukins, neopterin, interferon-gamma and tumour necrosis factor-alpha in cerebrospinal fluid of patients with dementia of the Alzheimer type
    • Engelborghs S., De Brabander M., De Cree J., D'Hooge R., Geerts H., Verhaegen H., De Deyn P.P. Unchanged levels of interleukins, neopterin, interferon-gamma and tumour necrosis factor-alpha in cerebrospinal fluid of patients with dementia of the Alzheimer type. Neurochem. Int. 34:1999;523-530.
    • (1999) Neurochem. Int. , vol.34 , pp. 523-530
    • Engelborghs, S.1    De Brabander, M.2    De Cree, J.3    D'Hooge, R.4    Geerts, H.5    Verhaegen, H.6    De Deyn, P.P.7
  • 13
    • 0016823810 scopus 로고
    • Mini-mental state: A practical methods for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., McHug P.R. Mini-mental state: a practical methods for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12:1975;189-198.
    • (1975) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHug, P.R.3
  • 15
    • 0034957469 scopus 로고    scopus 로고
    • Is anti-cholinesterase therapy of Alzheimer's disease delaying progression?
    • Giacobini E. Is anti-cholinesterase therapy of Alzheimer's disease delaying progression? Aging. 13:2001;247-254.
    • (2001) Aging , vol.13 , pp. 247-254
    • Giacobini, E.1
  • 17
    • 0028926976 scopus 로고
    • Interleukin-1 expression in different plaque types in AD: Significance in plaque evolution
    • Griffin W.S.T., Sheng J.G., Roberts G.W., Mrak R.E. Interleukin-1 expression in different plaque types in AD: significance in plaque evolution. J. Neuropathol. Exp. Neurol. 54:1995;276-281.
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 276-281
    • Griffin, W.S.T.1    Sheng, J.G.2    Roberts, G.W.3    Mrak, R.E.4
  • 18
    • 0000999931 scopus 로고
    • Potential anti-inflammatory effects of interleukin 4: Suppression of human monocyte tumour necrosis factor alpha, interleukin 1 and prostaglandin E2
    • Hart P.H., Vitti G.F., Buegess D.R., Whitty G.A., Piccoli D.S., Hamilton J.A. Potential anti-inflammatory effects of interleukin 4: suppression of human monocyte tumour necrosis factor alpha, interleukin 1 and prostaglandin E2. Proc. Natl. Acad. Sci. U. S. A. 86:1989;3803-3807.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 3803-3807
    • Hart, P.H.1    Vitti, G.F.2    Buegess, D.R.3    Whitty, G.A.4    Piccoli, D.S.5    Hamilton, J.A.6
  • 19
    • 0029051259 scopus 로고
    • Interleukin-6 is present in early stage of plaque formation and is restricted to the brains of Alzheimer's disease patients
    • Huell M., Strauss S., Volk B., Berger M., Bauer J. Interleukin-6 is present in early stage of plaque formation and is restricted to the brains of Alzheimer's disease patients. Acta Neuropathol. (Berl.). 89:1995;544-551.
    • (1995) Acta Neuropathol. (Berl.) , vol.89 , pp. 544-551
    • Huell, M.1    Strauss, S.2    Volk, B.3    Berger, M.4    Bauer, J.5
  • 23
    • 0037470612 scopus 로고    scopus 로고
    • The lymphocytic cholinergic system and its biological function
    • Kawashima K., Fujii T. The lymphocytic cholinergic system and its biological function. Life Sci. 72:2003;2101-2109.
    • (2003) Life Sci. , vol.72 , pp. 2101-2109
    • Kawashima, K.1    Fujii, T.2
  • 24
    • 0032406078 scopus 로고    scopus 로고
    • Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: Interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumour necrosis factor-alpha, the soluble tumour necrosis factor receptors I and II, and alpha1-antichymotrypsin
    • Lanzrein A.S., Johnston C.M., Perry V.H., Jobst K.A., King E.M., Smith A.D. Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumour necrosis factor-alpha, the soluble tumour necrosis factor receptors I and II, and alpha1-antichymotrypsin. Alzheimer Dis. Assoc. Disord. 12:1998;215-227.
    • (1998) Alzheimer Dis. Assoc. Disord. , vol.12 , pp. 215-227
    • Lanzrein, A.S.1    Johnston, C.M.2    Perry, V.H.3    Jobst, K.A.4    King, E.M.5    Smith, A.D.6
  • 25
    • 0034032594 scopus 로고    scopus 로고
    • Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells
    • Ledeboer A., Breve J.J., Poole S., Tilders F.J., Van Dam A.M. Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Glia. 30:2000;134-142.
    • (2000) Glia , vol.30 , pp. 134-142
    • Ledeboer, A.1    Breve, J.J.2    Poole, S.3    Tilders, F.J.4    Van Dam, A.M.5
  • 26
    • 0028924973 scopus 로고
    • Interleukin-4 inhibits the expression of tumour necrosis factors alpha and beta, interleukins-1 beta and -6 and interferon-gamma
    • Lee J.D., Rhoades K., Economou J.S. Interleukin-4 inhibits the expression of tumour necrosis factors alpha and beta, interleukins-1 beta and -6 and interferon-gamma. Immunol. Cell Biol. 73:1995;57-61.
    • (1995) Immunol. Cell Biol. , vol.73 , pp. 57-61
    • Lee, J.D.1    Rhoades, K.2    Economou, J.S.3
  • 27
    • 0033966340 scopus 로고    scopus 로고
    • Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: Peripheral inflammation or signals from the brain?
    • Licastro F., Pedrini S., Caputo L., Annoni G., Davis L.J., Ferri C., Casadei V., Grimaldi L.M. Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain? J. Neuroimmunol. 103:2000;97-102.
    • (2000) J. Neuroimmunol. , vol.103 , pp. 97-102
    • Licastro, F.1    Pedrini, S.2    Caputo, L.3    Annoni, G.4    Davis, L.J.5    Ferri, C.6    Casadei, V.7    Grimaldi, L.M.8
  • 28
    • 0032964511 scopus 로고    scopus 로고
    • Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy an Alzheimer disease (AD) individuals
    • Lombardi V.R.M., Garcia M., Rey L., Cacabelos R. Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy an Alzheimer disease (AD) individuals. J. Neuroimmunol. 97:1999;163-171.
    • (1999) J. Neuroimmunol. , vol.97 , pp. 163-171
    • Lombardi, V.R.M.1    Garcia, M.2    Rey, L.3    Cacabelos, R.4
  • 29
    • 0030827642 scopus 로고    scopus 로고
    • Association of vascular amyloid beta and cells of the mononuclear phagocyte system in hereditary cerebral hemorrhage with amyloidosis (Dutch) and Alzheimer disease
    • Maat-Schieman M.L., van Duinen S.G., Rozemuller A.J., Haan J., Ross R.A. Association of vascular amyloid beta and cells of the mononuclear phagocyte system in hereditary cerebral hemorrhage with amyloidosis (Dutch) and Alzheimer disease. J. Neuropathol. Exp. Neurol. 56:1997;273-284.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 273-284
    • Maat-Schieman, M.L.1    Van Duinen, S.G.2    Rozemuller, A.J.3    Haan, J.4    Ross, R.A.5
  • 31
    • 0032891880 scopus 로고    scopus 로고
    • Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with β-amyloid [25-35]
    • Meda L., Baron P., Prat E., Scarpini E., Scarlato G., Cassatela M.A., Rossi F. Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with β-amyloid [25-35]. J. Neuroimmunol. 93:1999;45-52.
    • (1999) J. Neuroimmunol. , vol.93 , pp. 45-52
    • Meda, L.1    Baron, P.2    Prat, E.3    Scarpini, E.4    Scarlato, G.5    Cassatela, M.A.6    Rossi, F.7
  • 32
    • 0031878352 scopus 로고    scopus 로고
    • Quantitative intracellular cytokine measurement: Age-related changes in proinflammatory cytokine production
    • O'Mahony L., Holland J., Jackson J., Feighery C., Hennessy T.P., Mealy K. Quantitative intracellular cytokine measurement: age-related changes in proinflammatory cytokine production. Clin. Exp. Immunol. 113:1998;213-219.
    • (1998) Clin. Exp. Immunol. , vol.113 , pp. 213-219
    • O'Mahony, L.1    Holland, J.2    Jackson, J.3    Feighery, C.4    Hennessy, T.P.5    Mealy, K.6
  • 36
    • 0031809196 scopus 로고    scopus 로고
    • Effects of an anti-IL-10 monoclonal antibody on rIFNbeta-1b-mediated immune modulation. Relevance to multiple sclerosis
    • Porrini A.M., De Luca G., Gambi D., Reder A.T. Effects of an anti-IL-10 monoclonal antibody on rIFNbeta-1b-mediated immune modulation. Relevance to multiple sclerosis. J. Neuroimmunol. 81:1998;109-115.
    • (1998) J. Neuroimmunol. , vol.81 , pp. 109-115
    • Porrini, A.M.1    De Luca, G.2    Gambi, D.3    Reder, A.T.4
  • 37
    • 0030583248 scopus 로고    scopus 로고
    • Synergistic induction of nitric oxide by β-amyloid and cytokines in astrocytes
    • Rossi F., Bianchini E. Synergistic induction of nitric oxide by β-amyloid and cytokines in astrocytes. Biochem. Biophys. Res. Commun. 225:1996;474-478.
    • (1996) Biochem. Biophys. Res. Commun. , vol.225 , pp. 474-478
    • Rossi, F.1    Bianchini, E.2
  • 38
    • 0028869476 scopus 로고
    • Cytokines and the nervous system: II. Actions and mechanisms of action
    • Rothwell N.J., Hopkins S.J. Cytokines and the nervous system: II. Actions and mechanisms of action. Trends Neurosci. 18:1995;130-136.
    • (1995) Trends Neurosci. , vol.18 , pp. 130-136
    • Rothwell, N.J.1    Hopkins, S.J.2
  • 39
    • 0007692414 scopus 로고    scopus 로고
    • In vivo, and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis
    • Sheng J.G., Ito K., Skinner R.D., Mrak R.E., Rovnaghi C.R., van Eldik L.J., Griffin W.S.T. In vivo, and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis. Neurobiol. Aging. 17:1996;761-766.
    • (1996) Neurobiol. Aging , vol.17 , pp. 761-766
    • Sheng, J.G.1    Ito, K.2    Skinner, R.D.3    Mrak, R.E.4    Rovnaghi, C.R.5    Van Eldik, L.J.6    Griffin, W.S.T.7
  • 41
    • 0036018238 scopus 로고    scopus 로고
    • TH1/TH2 cytokines in the central nervous system
    • Sredni-Kenigsbuch D. TH1/TH2 cytokines in the central nervous system. Int. J. Neurosci. 112:2002;665-703.
    • (2002) Int. J. Neurosci. , vol.112 , pp. 665-703
    • Sredni-Kenigsbuch, D.1
  • 42
    • 0035255055 scopus 로고    scopus 로고
    • IL-4, IL-10 and IL-13 modulate A-beta(1-42)-induced cytokine and chemokines production in primary murine microglia and a human cell line
    • Szcepanik A.M., Funes S., Petko W., Ringheim G.E. IL-4, IL-10 and IL-13 modulate A-beta(1-42)-induced cytokine and chemokines production in primary murine microglia and a human cell line. J. Neuroimmunol. 113:2001;49-62.
    • (2001) J. Neuroimmunol. , vol.113 , pp. 49-62
    • Szcepanik, A.M.1    Funes, S.2    Petko, W.3    Ringheim, G.E.4
  • 43
    • 0035085610 scopus 로고    scopus 로고
    • Amyloid-beta peptide fragment p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo
    • Szczepanik A.M., Rampe D., Ringheim G.E. Amyloid-beta peptide fragment p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo. J. Neurochem. 77:2001;304-317.
    • (2001) J. Neurochem. , vol.77 , pp. 304-317
    • Szczepanik, A.M.1    Rampe, D.2    Ringheim, G.E.3
  • 44
    • 0035803879 scopus 로고    scopus 로고
    • Peripheral blood lymphocytes muscarinic cholinergic receptor subtypes in Alzheimer's disease: A marker of cholinergic dysfunction?
    • Tayebati S.K., Amenta F., Amici S., El-Assouad D., Gallai V., Ricci A., Parnetti L. Peripheral blood lymphocytes muscarinic cholinergic receptor subtypes in Alzheimer's disease: a marker of cholinergic dysfunction? J. Neuroimmunol. 121:2001;126-131.
    • (2001) J. Neuroimmunol. , vol.121 , pp. 126-131
    • Tayebati, S.K.1    Amenta, F.2    Amici, S.3    El-Assouad, D.4    Gallai, V.5    Ricci, A.6    Parnetti, L.7
  • 45
    • 0025133545 scopus 로고
    • Interleukin-4 (IL-4) inhibits secretion of IL-1beta, tumour necrosis factor alpha, and IL-6 by human monocytes
    • te Velde A.A., Huijbens R.J., Heije K., de Vries J.E., Figdor C.G. Interleukin-4 (IL-4) inhibits secretion of IL-1beta, tumour necrosis factor alpha, and IL-6 by human monocytes. Blood. 76:1990;1392-1397.
    • (1990) Blood , vol.76 , pp. 1392-1397
    • Te Velde, A.A.1    Huijbens, R.J.2    Heije, K.3    De Vries, J.E.4    Figdor, C.G.5
  • 46
    • 0035859879 scopus 로고    scopus 로고
    • A 1-year, randomized, placebo-controlled study of Donepezil in patients with mild to moderate AD
    • Winblad B., Engedal K., Soininen H. A 1-year, randomized, placebo-controlled study of Donepezil in patients with mild to moderate AD. Neurology. 57:2001;489-495.
    • (2001) Neurology , vol.57 , pp. 489-495
    • Winblad, B.1    Engedal, K.2    Soininen, H.3
  • 47
    • 0033982028 scopus 로고    scopus 로고
    • Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia
    • Yates S.L., Burgess L.H., Kocsis-Angle J., Antal J.M., Dority M.D., Embury P.B., Piotrkowski A.M., Brunden K.R. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J. Neurochem. 74:2000;1017-1025.
    • (2000) J. Neurochem. , vol.74 , pp. 1017-1025
    • Yates, S.L.1    Burgess, L.H.2    Kocsis-Angle, J.3    Antal, J.M.4    Dority, M.D.5    Embury, P.B.6    Piotrkowski, A.M.7    Brunden, K.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.