Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: Potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine

Journal of Neurochemistry

Volumn 102, Issue 3, 2007, Pages 753-760

  Chan, Amy ^a   Shea, Thomas B ^a  

^a University of Massachusetts Lowell   (United States)

Author keywords

Abeta; Alzheimer's disease; Apolipoprotein E; Folate; Gamma secretase; Presenilin; S adenosylmethionine

Indexed keywords

ABETALIPOPROTEIN; ALPHA TOCOPHEROL; APOLIPOPROTEIN E; FOLIC ACID; GAMMA SECRETASE; IRON; LIPOPROTEIN; PRESENILIN 1; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG POTENTIATION; ENZYME ACTIVITY; FOLIC ACID DEFICIENCY; GENETIC RISK; HOMOZYGOSITY; HYPERLIPOPROTEINEMIA TYPE 3; MOUSE; NERVE DEGENERATION; NEUROCHEMISTRY; NONHUMAN; NUTRITIONAL ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK ASSESSMENT; SCORING SYSTEM; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOLIPOPROTEINS E; BRAIN; DIETARY SUPPLEMENTS; FOLIC ACID DEFICIENCY; FOOD, FORMULATED; IRON, DIETARY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; PRESENILINS; S-ADENOSYLMETHIONINE; UP-REGULATION; VITAMIN E DEFICIENCY;

MURINAE; MUS; MUS MUSCULUS;

EID: 34447305738     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04589.x     Document Type: Article

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