Inflammatory mechanisms in Alzheimer's disease: Inhibition of β- amyloid-stimulated proinflammatory responses and neurotoxicity by PPARγ agonists

Journal of Neuroscience

Volumn 20, Issue 2, 2000, Pages 558-567

  Combs, Colin K ^a   Johnson, Derrick E ^a   Karlo, J Colleen ^a   Cannady, Steven B ^a   Landreth, Gary E ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; COX 2; Cyclooxygenase; Cytokines; IL 6; Inflammation; Microgila; Neurotoxicity; NSAIDs; PPAR ; Signal transduction; THP 1 monocytes; TNF ; Tyrosine kinase; amyloid

Indexed keywords

AMYLOID BETA PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROTEIN TYROSINE KINASE; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; LIGAND BINDING; MACROPHAGE ACTIVATION; MICROGLIA; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0034651101     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-02-00558.2000     Document Type: Article

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