Interleukin-1β Induces A Reactive Astroglial Phenotype Via Deactivation of the Rho GTPase-Rock Axis

Journal of Neuroscience

Volumn 24, Issue 11, 2004, Pages 2837-2845

  John, Gareth R ^a,b   Chen, Lanfen ^b   Rivieccio, Mark A ^b   Melendez Vasquez, Carmen V ^c   Hartley, Adam ^b   Brosnan, Celia F ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocyte; Focal adhesions; Inflammation; Interleukin; Myosin; RhoA

Indexed keywords

ADAPTOR PROTEIN; EZRIN; FOCAL ADHESION KINASE; INTERLEUKIN 1BETA; MOESIN; MYOSIN; MYOSIN LIGHT CHAIN; RADIXIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; DNA BINDING PROTEIN; ENZYME INHIBITOR; ETV5 PROTEIN, HUMAN; INTERLEUKIN 1; PROTEIN SERINE THREONINE KINASE; RHO KINASE; RHO-ASSOCIATED KINASE; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

ARTICLE; ASTROCYTOSIS; BRAIN INJURY; CELL MIGRATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME MECHANISM; FETUS; FOCAL ADHESION; HUMAN; HUMAN CELL; INFLAMMATION; MACROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SCAR; ASTROCYTE; CELL CULTURE; CELL MOTION; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TIME; ULTRASTRUCTURE;

ASTROCYTES; CELL MOVEMENT; CELLS, CULTURED; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FETUS; FOCAL ADHESIONS; HUMANS; INTERLEUKIN-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHENOTYPE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 1642407666     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4789-03.2004     Document Type: Article

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