LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

Neurobiology of Aging

Volumn 32, Issue 12, 2011, Pages 2323.e1-2323.e11

  Pflanzner, Thorsten ^a   Janko, Maren C ^a   André Dohmen, Bettina ^a   Reuss, Stefan ^a   Weggen, Sascha ^b   Roebroek, Anton J M ^c   Kuhlmann, Christoph R W ^a   Pietrzik, Claus U ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Alzheimer's disease; Amyloid ; Blood brain barrier; Low density lipoprotein receptor related protein 1; NPxYxxL motif; Transcytosis

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; CONTROLLED STUDY; ENDOCYTOSIS; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; TRANSCYTOSIS;

EID: 80053652475     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.05.025     Document Type: Article

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