-
1
-
-
0037638809
-
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
-
P.S. Aisen, K.A. Schafer, M. Grundman, E. Pfeiffer, M. Sano and K.L. Davis, Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial, JAMA 289 (2003), 2819-2826.
-
(2003)
JAMA
, vol.289
, pp. 2819-2826
-
-
Aisen, P.S.1
Schafer, K.A.2
Grundman, M.3
Pfeiffer, E.4
Sano, M.5
Davis, K.L.6
-
2
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
H. Akiyama, S. Barger, S. Barnum, B. Bradt, J. Bauer, G.M. Cole, N.R. Cooper, P. Eikelenboom, M. Emmerling, B.L. Fiebich, C.E. Finch, S. Frautschy, W.S. Griffin, H. Hampel, M. Hull, G. Landreth, L. Lue, R. Mrak, I.R. Mackenzie, P.L. McGeer, M.K. O'Banion, J. Pachter, G. Pasinetti, C. Plata-Salaman, J. Rogers, R. Rydel, Y. Shen, W. Streit, R. Strohmeyer, I. Tooyoma, F.L. Van Muiswinkel, R. Veerhuis, D. Walker, S. Webster, B. Wegrzyniak, G. Wenk and T. Wyss-Coray, Inflammation and Alzheimer's disease, Neurobiol Aging 21 (2000), 383-421.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
Cooper, N.R.7
Eikelenboom, P.8
Emmerling, M.9
Fiebich, B.L.10
Finch, C.E.11
Frautschy, S.12
Griffin, W.S.13
Hampel, H.14
Hull, M.15
Landreth, G.16
Lue, L.17
Mrak, R.18
Mackenzie, I.R.19
McGeer, P.L.20
O'Banion, M.K.21
Pachter, J.22
Pasinetti, G.23
Plata-Salaman, C.24
Rogers, J.25
Rydel, R.26
Shen, Y.27
Streit, W.28
Strohmeyer, R.29
Tooyoma, I.30
Van Muiswinkel, F.L.31
Veerhuis, R.32
Walker, D.33
Webster, S.34
Wegrzyniak, B.35
Wenk, G.36
Wyss-Coray, T.37
more..
-
3
-
-
0032978006
-
Overexpression of tumour necrosis factor alpha in the brain of transgenic mice differentially alters nerve growth factor levels and choline acetyltransferase activity
-
L. Aloe, M. Fiore, L. Probert, P. Turrini and P. Tirassa, Overexpression of tumour necrosis factor alpha in the brain of transgenic mice differentially alters nerve growth factor levels and choline acetyltransferase activity, Cytokine 11 (1999), 45-54.
-
(1999)
Cytokine
, vol.11
, pp. 45-54
-
-
Aloe, L.1
Fiore, M.2
Probert, L.3
Turrini, P.4
Tirassa, P.5
-
4
-
-
0037363169
-
Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide
-
J.M. Andersen, O. Myhre, H. Aarnes, T.A. Vestad and F. Fonnum, Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide, Free Radic Res 37 (2003), 269-279.
-
(2003)
Free Radic Res
, vol.37
, pp. 269-279
-
-
Andersen, J.M.1
Myhre, O.2
Aarnes, H.3
Vestad, T.A.4
Fonnum, F.5
-
5
-
-
17444435925
-
Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid
-
Y. Ando, T. Brannstrom, K. Uchida, N. Nyhlin, B. Nasman, O. Suhr, T. Yamashita, T. Olsson, M. El Salhy, M. Uchino and M. Ando, Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid, J Neurol Sci 156 (1998), 172-176.
-
(1998)
J Neurol Sci
, vol.156
, pp. 172-176
-
-
Ando, Y.1
Brannstrom, T.2
Uchida, K.3
Nyhlin, N.4
Nasman, B.5
Suhr, O.6
Yamashita, T.7
Olsson, T.8
El Salhy, M.9
Uchino, M.10
Ando, M.11
-
6
-
-
0031784348
-
Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
P.K. Andrus, T.J. Fleck, M.E. Gurney and E.D. Hall, Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis, J Neurochem 71 (1998), 2041-2048.
-
(1998)
J Neurochem
, vol.71
, pp. 2041-2048
-
-
Andrus, P.K.1
Fleck, T.J.2
Gurney, M.E.3
Hall, E.D.4
-
7
-
-
0031149081
-
Altered apolipoprotein E secretion in cytokine treated human astrocyte cultures
-
F. Baskin, G.M. Smith, J.A. Fosmire and R.N. Rosenberg, Altered apolipoprotein E secretion in cytokine treated human astrocyte cultures, J Neurol Sci 148 (1997), 15-18.
-
(1997)
J Neurol Sci
, vol.148
, pp. 15-18
-
-
Baskin, F.1
Smith, G.M.2
Fosmire, J.A.3
Rosenberg, R.N.4
-
9
-
-
0030851761
-
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
-
M.F. Beal, R.J. Ferrante, S.E. Browne, R.T. Matthews, N.W. Kowall and R.H. Brown Jr, Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis, Ann Neurol 42 (1997), 644-654.
-
(1997)
Ann Neurol
, vol.42
, pp. 644-654
-
-
Beal, M.F.1
Ferrante, R.J.2
Browne, S.E.3
Matthews, R.T.4
Kowall, N.W.5
Brown Jr., R.H.6
-
10
-
-
0032621790
-
TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs
-
I. Blasko, F. Marx, E. Steiner, T. Hartmann and B. Grubeck-Loebenstein, TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs, FASEB J 13 (1999), 63-68.
-
(1999)
FASEB J
, vol.13
, pp. 63-68
-
-
Blasko, I.1
Marx, F.2
Steiner, E.3
Hartmann, T.4
Grubeck-Loebenstein, B.5
-
11
-
-
0034961104
-
Amyotrophic lateral sclerosis: Pathogenesis
-
R.H. Brown, Jr. and W. Robberecht, Amyotrophic lateral sclerosis: pathogenesis, Semen Neurol 21 (2001), 131-139.
-
(2001)
Semen Neurol
, vol.21
, pp. 131-139
-
-
Brown Jr., R.H.1
Robberecht, W.2
-
12
-
-
0030806228
-
Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
-
L.I. Bruijn, M.F. Beal, M.W. Becher, J.B. Schulz, RC. Wong, D.L. Price and D.W. Cleveland, Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant, Proc Natl Acad Sci USA 94 (1997), 7606-7611.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7606-7611
-
-
Bruijn, L.I.1
Beal, M.F.2
Becher, M.W.3
Schulz, J.B.4
Wong, R.C.5
Price, D.L.6
Cleveland, D.W.7
-
13
-
-
0036451446
-
Molecular and functional dissection of TGF-beta1-induced cerebrovascular abnormalities in transgenic mice
-
M. Buckwalter, J.P. Pepper, R.F. Gaertner, D. Von Euw, P. Lacombe and T. Wyss-Coray, Molecular and functional dissection of TGF-beta1-induced cerebrovascular abnormalities in transgenic mice, Ann N Y Acad Sci 977 (2002), 87-95.
-
(2002)
Ann N Y Acad Sci
, vol.977
, pp. 87-95
-
-
Buckwalter, M.1
Pepper, J.P.2
Gaertner, R.F.3
Von Euw, D.4
Lacombe, P.5
Wyss-Coray, T.6
-
14
-
-
0028094017
-
Transforming growth factor beta in Alzheimer's disease
-
C.C. Chao, S. Hu, W.H. Frey, T.A. Ala, W.W. Tourtellotte and P.K. Peterson, Transforming growth factor beta in Alzheimer's disease, Clin Diagn Lab Immunol 1 (1994), 109-110.
-
(1994)
Clin Diagn Lab Immunol
, vol.1
, pp. 109-110
-
-
Chao, C.C.1
Hu, S.2
Frey, W.H.3
Ala, T.A.4
Tourtellotte, W.W.5
Peterson, P.K.6
-
15
-
-
0030250758
-
Neuroglial-mediated immununoinflammatory responses in Alzheimer's disease: Complement activation and therapeutic approaches
-
S. Chen, R.C. Frederickson and K.R. Brunden, Neuroglial-mediated immununoinflammatory responses in Alzheimer's disease: complement activation and therapeutic approaches, Neurobiol Aging 17 (1996), 781-787.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 781-787
-
-
Chen, S.1
Frederickson, R.C.2
Brunden, K.R.3
-
16
-
-
0023642584
-
Production of superoxide anions by a CNS macrophage, the microglia
-
C.A. Colton and D.L. Gilbert, Production of superoxide anions by a CNS macrophage, the microglia, FEBS Lett 223 (1987), 284-288.
-
(1987)
FEBS Lett
, vol.223
, pp. 284-288
-
-
Colton, C.A.1
Gilbert, D.L.2
-
17
-
-
0030833449
-
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite
-
J.P. Crow, J.B. Sampson, Y. Zhuang, J.A. Thompson and J.S. Beckman, Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite, J Neurochem 69 (1997), 1936-1944.
-
(1997)
J Neurochem
, vol.69
, pp. 1936-1944
-
-
Crow, J.P.1
Sampson, J.B.2
Zhuang, Y.3
Thompson, J.A.4
Beckman, J.S.5
-
18
-
-
0028889206
-
Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1
-
S. Das and H. Potter, Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1, Neuron 14 (1995), 447-456.
-
(1995)
Neuron
, vol.14
, pp. 447-456
-
-
Das, S.1
Potter, H.2
-
19
-
-
0032983334
-
2 forming NADPH oxidase in microglia, monocytes and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease
-
2 forming NADPH oxidase in microglia, monocytes and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease, J Biol Chem 274 (1999), 15493-15499.
-
(1999)
J Biol Chem
, vol.274
, pp. 15493-15499
-
-
Del Bianca, V.1
Dusi, S.2
Bianchini, E.3
Dal Pra, I.4
Rossi, F.5
-
20
-
-
0019993831
-
Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study
-
P. Eikelenboom and F.C. Stam, Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study, Acta Neuropathol (Berl) 57 (1982), 239-242.
-
(1982)
Acta Neuropathol (Berl)
, vol.57
, pp. 239-242
-
-
Eikelenboom, P.1
Stam, F.C.2
-
21
-
-
0030250852
-
The role of complement and activated microglia in the pathogenesis of Alzheimer's disease
-
P. Eikelenboom and R. Veerhuis, The role of complement and activated microglia in the pathogenesis of Alzheimer's disease, Neurobiol Aging 17 (1996), 673-680.
-
(1996)
Neurobiol Aging
, vol.17
, pp. 673-680
-
-
Eikelenboom, P.1
Veerhuis, R.2
-
22
-
-
0035500386
-
Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
-
J.L. Elliott, Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis, Brain Res Mol Brain Res 95 (2001), 172-178.
-
(2001)
Brain Res Mol Brain Res
, vol.95
, pp. 172-178
-
-
Elliott, J.L.1
-
23
-
-
0025807206
-
Elevated circulating TNF levels in Alzheimer's disease
-
H. Fillit, W.H. Ding and L. Buee, Elevated circulating TNF levels in Alzheimer's disease, Neurosci Lett 129 (1991), 318-320.
-
(1991)
Neurosci Lett
, vol.129
, pp. 318-320
-
-
Fillit, H.1
Ding, W.H.2
Buee, L.3
-
24
-
-
0035686083
-
Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology
-
S.A. Frautschy, W. Hu, P. Kim, S.A. Miller, T. Chu, M.E. Harris-White and G.M. Cole, Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology, Neurobiol Aging 22 (2001), 993-1005.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 993-1005
-
-
Frautschy, S.A.1
Hu, W.2
Kim, P.3
Miller, S.A.4
Chu, T.5
Harris-White, M.E.6
Cole, G.M.7
-
25
-
-
1842407161
-
Inhibition of ICE slows ALS in mice
-
R.M. Friedlander, R.H. Brown, V. Gagliardini, J. Wang and J. Yuan, Inhibition of ICE slows ALS in mice, Nature 388 (1997), 31.
-
(1997)
Nature
, vol.388
, pp. 31
-
-
Friedlander, R.M.1
Brown, R.H.2
Gagliardini, V.3
Wang, J.4
Yuan, J.5
-
26
-
-
0025005862
-
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
-
J.Y. Fu, J.L. Masferrer, K. Seibert, A. Raz and P. Needleman, The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes, J Biol Chem 265 (1990), 16737-16740.
-
(1990)
J Biol Chem
, vol.265
, pp. 16737-16740
-
-
Fu, J.Y.1
Masferrer, J.L.2
Seibert, K.3
Raz, A.4
Needleman, P.5
-
27
-
-
0035976575
-
Prostaglandins and leukotrienes: Advances in eicosanoid biology
-
C.D. Funk, Prostaglandins and leukotrienes: Advances in eicosanoid biology, Science 294 (2001), 1871-1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
28
-
-
0005775566
-
Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells
-
D. Goldgaber, H.W. Harris, T. Hla, T. Maciag, R.J. Donnelly, J.S. Jacobsen, M.P. Vitek and D.C. Gajdusek, Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells, Proc Natl Acad Sci USA 86 (1989), 7606-7610.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7606-7610
-
-
Goldgaber, D.1
Harris, H.W.2
Hla, T.3
Maciag, T.4
Donnelly, R.J.5
Jacobsen, J.S.6
Vitek, M.P.7
Gajdusek, D.C.8
-
29
-
-
0029902166
-
Evidence of neuronal oxidative damage in Alzheimer's disease
-
P.F. Good, P. Werner, A. Hsu, C.W. Olanow and D.P. Perl, Evidence of neuronal oxidative damage in Alzheimer's disease, Am J Pathol 149 (1996), 21-28.
-
(1996)
Am J Pathol
, vol.149
, pp. 21-28
-
-
Good, P.F.1
Werner, P.2
Hsu, A.3
Olanow, C.W.4
Perl, D.P.5
-
30
-
-
0001360461
-
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
-
W.S. Griffin, L.C. Stanley, C. Ling, L. White, V. MacLeod, L.J. Perrot, C.L. White 3rd and C. Araoz, Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease, Proc Natl Acad Sci USA 86 (1989), 7611-7615.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7611-7615
-
-
Griffin, W.S.1
Stanley, L.C.2
Ling, C.3
White, L.4
MacLeod, V.5
Perrot, L.J.6
White III, C.L.7
Araoz, C.8
-
31
-
-
0028926976
-
Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution
-
W.S. Griffin, J.G. Sheng, G.W. Roberts and R.E. Mrak, Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution, J Neuropathol Exp Neurol 54 (1995), 276-281.
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 276-281
-
-
Griffin, W.S.1
Sheng, J.G.2
Roberts, G.W.3
Mrak, R.E.4
-
32
-
-
0037101616
-
Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis
-
J.T. Guo, J. Yu, D. Grass, F.C. de Beer and M.S. Kindy, Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis, J Neurosci 22 (2002), 5900-5909.
-
(2002)
J Neurosci
, vol.22
, pp. 5900-5909
-
-
Guo, J.T.1
Yu, J.2
Grass, D.3
De Beer, F.C.4
Kindy, M.S.5
-
33
-
-
0036163923
-
Familial amyotrophic lateral sclerosis
-
C.K. Hand and G.A. Rouleau, Familial amyotrophic lateral sclerosis, Muscle Nerve 25 (2002), 135-159.
-
(2002)
Muscle Nerve
, vol.25
, pp. 135-159
-
-
Hand, C.K.1
Rouleau, G.A.2
-
34
-
-
0037023277
-
Inducible nitric oxide synthase and argininosuccinate synthetase: Co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with beta-amyloid 1-42 in vitro
-
J. Haas, B. Storch-Hagenlocher, A. Biessmann and B. Wildemann, Inducible nitric oxide synthase and argininosuccinate synthetase: co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with beta-amyloid 1-42 in vitro, Neurosci Lett 322 (2002), 121-125.
-
(2002)
Neurosci Lett
, vol.322
, pp. 121-125
-
-
Haas, J.1
Storch-Hagenlocher, B.2
Biessmann, A.3
Wildemann, B.4
-
35
-
-
0028180518
-
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
-
K. Hensley, J.M. Carney, M.P. Mattson, M. Aksenova, M. Harris, J.F. Wu, R.A. Floyd and D.A. Butterfield, A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease, Proc Natl Acad Sci USA 91 (1994), 3270-3274.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
36
-
-
0041833409
-
Message and protein-level elevation of tumor necrosis factor α (TNFα) and TNFα-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis
-
in press
-
K. Hensley, J. Fedynychyn, S. Ferrel, R.A. Floyd, B. Gordon, P. Grammas, L. Hamdheydari, M. Mhatre, S. Mou, Q.N. Pye, C. Stewart, M. West, S. West and K. Williamson. Message and protein-level elevation of tumor necrosis factor α (TNFα) and TNFα-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis, Neurobiology of Disease (in press).
-
Neurobiology of Disease
-
-
Hensley, K.1
Fedynychyn, J.2
Ferrel, S.3
Floyd, R.A.4
Gordon, B.5
Grammas, P.6
Hamdheydari, L.7
Mhatre, M.8
Mou, S.9
Pye, Q.N.10
Stewart, C.11
West, M.12
West, S.13
Williamson, K.14
-
37
-
-
0036062628
-
Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
-
K. Hensley, R.A. Floyd, B. Gordon, S. Mou, Q.N. Pye, C.A. Stewart, M. West and K.S. Williamson, Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis, J Neurochem 82 (2002), 365-374.
-
(2002)
J Neurochem
, vol.82
, pp. 365-374
-
-
Hensley, K.1
Floyd, R.A.2
Gordon, B.3
Mou, S.4
Pye, Q.N.5
Stewart, C.A.6
West, M.7
Williamson, K.S.8
-
38
-
-
0032531735
-
Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation
-
K. Hensley, M.L. Maidt, Z. Yu, H. Sang, W.R. Markesbery and R.A. Floyd, Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation, J Neurosci 18 (1998), 8126-8132.
-
(1998)
J Neurosci
, vol.18
, pp. 8126-8132
-
-
Hensley, K.1
Maidt, M.L.2
Yu, Z.3
Sang, H.4
Markesbery, W.R.5
Floyd, R.A.6
-
39
-
-
0031010334
-
Nitric oxide and derived species as toxic agents in stroke, AIDS dementia, and chronic neurodegenerative disorders
-
K. Hensley, T. Tabatabaie, C.A. Stewart, Q. Pye and R.A. Floyd, Nitric oxide and derived species as toxic agents in stroke, AIDS dementia, and chronic neurodegenerative disorders, Chem Res Taxicol 10 (1997), 527-532.
-
(1997)
Chem Res Taxicol
, vol.10
, pp. 527-532
-
-
Hensley, K.1
Tabatabaie, T.2
Stewart, C.A.3
Pye, Q.4
Floyd, R.A.5
-
40
-
-
0033178889
-
Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease
-
L. Ho, C. Pieroni, D. Winger, D.P. Purohit, P.S. Aisen and G.M. Pasinetti, Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease, J Neurosci Res 57 (1999), 295-303.
-
(1999)
J Neurosci Res
, vol.57
, pp. 295-303
-
-
Ho, L.1
Pieroni, C.2
Winger, D.3
Purohit, D.P.4
Aisen, P.S.5
Pasinetti, G.M.6
-
41
-
-
18344414746
-
The Abeta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
X. Huang, C.S. Atwood, M.A. Hartshorn, G. Multhaup, L.E. Goldstein, R.C. Scarpa, M.P. Cuajungco, D.N. Gray, J. Lim, R.D. Moir, R.E. Tanzi and A.I. Bush, The Abeta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction, Biochemistry 38 (1999), 7609-7616.
-
(1999)
Biochemistry
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
42
-
-
0027294984
-
Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs
-
N. Hudson, M. Balsitis, S. Everitt and C.J. Hawkey, Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs, Gut 34 (1993), 742-747.
-
(1993)
Gut
, vol.34
, pp. 742-747
-
-
Hudson, N.1
Balsitis, M.2
Everitt, S.3
Hawkey, C.J.4
-
43
-
-
0035936004
-
Nonsteroidal anti-inflammatory drugs and risk of Alzheimer's disease
-
B.A. in t'Veld, A. Ruitenberg, A. Hofman, L.J. Launer, C.M. van Duijn, T. Stijnen, M.M. Breteler and B.H. Stricker, Nonsteroidal anti-inflammatory drugs and risk of Alzheimer's disease, N Engl J Med 345 (2001), 1515-1521.
-
(2001)
N Engl J Med
, vol.345
, pp. 1515-1521
-
-
In T'Veld, B.A.1
Ruitenberg, A.2
Hofman, A.3
Launer, L.J.4
Van Duijn, C.M.5
Stijnen, T.6
Breteler, M.M.7
Stricker, B.H.8
-
44
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
C. Jiang, A.T. Ting and B. Seed, PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines, Nature 391 (1998), 82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
45
-
-
0028178458
-
Beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain
-
H. Jiang, D. Burdick, C.G. Glabe, C.W. Cotman and AJ. Tenner, Beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain, J Immunol 152 (1994), 5050-5059.
-
(1994)
J Immunol
, vol.152
, pp. 5050-5059
-
-
Jiang, H.1
Burdick, D.2
Glabe, C.G.3
Cotman, C.W.4
Tenner, A.J.5
-
46
-
-
0030911815
-
Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs
-
J.Y. Jouzeau, B. Terlain, A. Abid, E. Nedelec and P. Netter, Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs, Drugs 53 (1997), 563-582.
-
(1997)
Drugs
, vol.53
, pp. 563-582
-
-
Jouzeau, J.Y.1
Terlain, B.2
Abid, A.3
Nedelec, E.4
Netter, P.5
-
47
-
-
0028990941
-
APOE-4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism
-
M.I. Kamboh, D.K. Sanghera, R.E. Ferrell and S.T. DeKosky, APOE-4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism, Nat Genet 10 (1995), 486-488.
-
(1995)
Nat Genet
, vol.10
, pp. 486-488
-
-
Kamboh, M.I.1
Sanghera, D.K.2
Ferrell, R.E.3
DeKosky, S.T.4
-
48
-
-
0030795049
-
Beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate
-
A. Klegeris and P.L. McGeer, Beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate, J Neurosci Res 49 (1997), 229-235.
-
(1997)
J Neurosci Res
, vol.49
, pp. 229-235
-
-
Klegeris, A.1
McGeer, P.L.2
-
49
-
-
0036753450
-
Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity
-
A. Klegeris and P.L. McGeer, Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity, Neurobiol Aging 23 (2002), 787-794.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 787-794
-
-
Klegeris, A.1
McGeer, P.L.2
-
50
-
-
0030756459
-
Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
V. Kostic, V. Jackson-Lewis, E de Bilbao, M. Dubois-Dauphin and S. Przedborski, Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis, Science 277 (1997), 559-562.
-
(1997)
Science
, vol.277
, pp. 559-562
-
-
Kostic, V.1
Jackson-Lewis, V.2
De Bilbao, E.3
Dubois-Dauphin, M.4
Przedborski, S.5
-
51
-
-
0029665941
-
Activation of phospholipase A2 by amyloid beta-peptides in vitro
-
J.Y. Lehtonen, J.M. Holopainen and P.K. Kinnunen, Activation of phospholipase A2 by amyloid beta-peptides in vitro, Biochemistry 35 (1996), 9407-9414.
-
(1996)
Biochemistry
, vol.35
, pp. 9407-9414
-
-
Lehtonen, J.Y.1
Holopainen, J.M.2
Kinnunen, P.K.3
-
52
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
M. Li, V.O. Ona, C. Guegan, M. Chen, V. Jackson-Lewis, L.J. Andrews, A.J. Olszewski, P.E. Stieg, J.P. Lee, S. Przedborski and R.M. Friedlander, Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model, Science 288 (2000), 335-339.
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Ona, V.O.2
Guegan, C.3
Chen, M.4
Jackson-Lewis, V.5
Andrews, L.J.6
Olszewski, A.J.7
Stieg, P.E.8
Lee, J.P.9
Przedborski, S.10
Friedlander, R.M.11
-
53
-
-
0033993523
-
Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression
-
Y. Li, L. Liu, J. Kang, J.G. Sheng, S.W. Barger, R.E. Mrak and W.S. Griffin, Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression, J Neurosci 20 (2000), 149-155.
-
(2000)
J Neurosci
, vol.20
, pp. 149-155
-
-
Li, Y.1
Liu, L.2
Kang, J.3
Sheng, J.G.4
Barger, S.W.5
Mrak, R.E.6
Griffin, W.S.7
-
54
-
-
0035691115
-
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
-
G.P. Lim, F. Yang, T. Chu, E. Gahtan, O. Ubeda, W. Beech, J.B. Overmier, K. Hsiao-Ashec, S.A. Frautschy and G.M. Cole, Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice, Neurobiol Aging 22 (2001), 983-991.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 983-991
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Gahtan, E.4
Ubeda, O.5
Beech, W.6
Overmier, J.B.7
Hsiao-Ashec, K.8
Frautschy, S.A.9
Cole, G.M.10
-
55
-
-
0034948192
-
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro
-
L.F. Lue, R. Rydel, E.F. Brigham, L.B. Yang, H. Hampel, G.M. Murphy Jr, L. Brachova, S.D. Yan, D.G. Walker, Y. Shen and J. Rogers, Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro, Glia 35 (2001), 72-79.
-
(2001)
Glia
, vol.35
, pp. 72-79
-
-
Lue, L.F.1
Rydel, R.2
Brigham, E.F.3
Yang, L.B.4
Hampel, H.5
Murphy Jr., G.M.6
Brachova, L.7
Yan, S.D.8
Walker, D.G.9
Shen, Y.10
Rogers, J.11
-
56
-
-
16044366720
-
Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein
-
T.J. Lyons, H. Liu, J.J. Goto, A. Nersissian, J.A. Roe, J.A. Graden, C. Cafe, L.M. Ellerby, D.E. Bredesen, E.B. Gralla and J. Valentine, Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein, Proc Natl Acad Sci USA 93 (1996), 12240-12244.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12240-12244
-
-
Lyons, T.J.1
Liu, H.2
Goto, J.J.3
Nersissian, A.4
Roe, J.A.5
Graden, J.A.6
Cafe, C.7
Ellerby, L.M.8
Bredesen, D.E.9
Gralla, E.B.10
Valentine, J.11
-
57
-
-
0031900411
-
Nonsteroidal antiinflammatory drug use and Alzheimer-type pathology in aging
-
I.R. Mackenzie and D.G. Munoz, Nonsteroidal antiinflammatory drug use and Alzheimer-type pathology in aging, Neurology 50 (1998), 986-990.
-
(1998)
Neurology
, vol.50
, pp. 986-990
-
-
Mackenzie, I.R.1
Munoz, D.G.2
-
58
-
-
0033937951
-
Putative role of neuronal 5-lipoxygenase in an aging brain
-
H. Manev, T. Uz, K. Sugaya and T. Qu, Putative role of neuronal 5-lipoxygenase in an aging brain, FASEB J 14 (2000), 1464-1469.
-
(2000)
FASEB J
, vol.14
, pp. 1464-1469
-
-
Manev, H.1
Uz, T.2
Sugaya, K.3
Qu, T.4
-
59
-
-
0032902974
-
Oxidative alterations in Alzheimer's disease
-
W.R. Markesbery and J.M. Carney, Oxidative alterations in Alzheimer's disease, Brain Pathol 9 (1999), 133-146.
-
(1999)
Brain Pathol
, vol.9
, pp. 133-146
-
-
Markesbery, W.R.1
Carney, J.M.2
-
60
-
-
0030961544
-
Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia
-
D.R. McDonald, K.R. Brunden and G.E. Landreth, Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia, J Neurosci 17 (1997), 2284-2294.
-
(1997)
J Neurosci
, vol.17
, pp. 2284-2294
-
-
McDonald, D.R.1
Brunden, K.R.2
Landreth, G.E.3
-
61
-
-
0024317005
-
Activation of the classical complement pathway in brain tissue of Alzheimer patients
-
P.L. McGeer, H. Aldyama, S. Itagaki and E.G. McGeer, Activation of the classical complement pathway in brain tissue of Alzheimer patients, Neurosci Lett 107 (1989), 341-346.
-
(1989)
Neurosci Lett
, vol.107
, pp. 341-346
-
-
McGeer, P.L.1
Aldyama, H.2
Itagaki, S.3
McGeer, E.G.4
-
62
-
-
0024442083
-
Immune system response in Alzheimer's disease
-
P.L. McGeer, H. Akiyama, S. Itagaki and E.G. McGeer, Immune system response in Alzheimer's disease, Can J Neurol Sci 16 (1989), 516-527.
-
(1989)
Can J Neurol Sci
, vol.16
, pp. 516-527
-
-
McGeer, P.L.1
Akiyama, H.2
Itagaki, S.3
McGeer, E.G.4
-
63
-
-
0023633015
-
Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
-
P.L. McGeer, S. Itagaki, H. Tago and E.G. McGeer, Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR, Neurosci Lett 79 (1987), 195-200.
-
(1987)
Neurosci Lett
, vol.79
, pp. 195-200
-
-
McGeer, P.L.1
Itagaki, S.2
Tago, H.3
McGeer, E.G.4
-
64
-
-
0025332027
-
Antiinflammatory drugs and Alzheimer's disease
-
P.L. McGeer, E.G. McGeer, J. Rogers and J. Sibley, Antiinflammatory drugs and Alzheimer's disease, Lancet 335 (1990), 1037.
-
(1990)
Lancet
, vol.335
, pp. 1037
-
-
McGeer, P.L.1
McGeer, E.G.2
Rogers, J.3
Sibley, J.4
-
65
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
P.L. McGeer, M. Schulzer and E.G. McGeer, Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies, Neurology 47 (1996), 425-432.
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
66
-
-
0035835451
-
Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: A case-control study
-
S.M. McCusker, M.D. Curran, K.B. Dynan, C.D. McCullagh, D.D. Urquhart, D. Middleton, C.C. Patterson, S.P. McIlroy and A.P. Passmore, Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study, Lancet 357 (2001), 436-439.
-
(2001)
Lancet
, vol.357
, pp. 436-439
-
-
McCusker, S.M.1
Curran, M.D.2
Dynan, K.B.3
McCullagh, C.D.4
Urquhart, D.D.5
Middleton, D.6
Patterson, C.C.7
McIlroy, S.P.8
Passmore, A.P.9
-
67
-
-
0035690720
-
Glial activation in Alzheimer's disease: The role of Abeta and its associated proteins
-
L. Meda, P. Baron and G. Scarlato, Glial activation in Alzheimer's disease: the role of Abeta and its associated proteins, Neurobiol Aging 22 (2001), 885-893.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 885-893
-
-
Meda, L.1
Baron, P.2
Scarlato, G.3
-
68
-
-
0030210955
-
Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells
-
L. Meda, S. Bernasconi, C. Bonaiuto, S. Sozzani, D. Zhou, L. Otvos Jr, A. Mantovani, F. Rossi and M.A. Cassatella, Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells, J Immunol 157 (1996), 1213-1218.
-
(1996)
J Immunol
, vol.157
, pp. 1213-1218
-
-
Meda, L.1
Bernasconi, S.2
Bonaiuto, C.3
Sozzani, S.4
Zhou, D.5
Otvos Jr., L.6
Mantovani, A.7
Rossi, F.8
Cassatella, M.A.9
-
69
-
-
0034053173
-
Association of interleukin-1 gene polymorphisms with Alzheimer's disease
-
J.A. Nicoll, R.E. Mrak, D.I. Graham, J. Stewart, G. Wilcock, S. MacGowan, M.M. Esiri, L.S. Murray, D. Dewar, S. Love, T. Moss and W.S. Griffin, Association of interleukin-1 gene polymorphisms with Alzheimer's disease, Ann Neurol 47 (2000), 365-368.
-
(2000)
Ann Neurol
, vol.47
, pp. 365-368
-
-
Nicoll, J.A.1
Mrak, R.E.2
Graham, D.I.3
Stewart, J.4
Wilcock, G.5
MacGowan, S.6
Esiri, M.M.7
Murray, L.S.8
Dewar, D.9
Love, S.10
Moss, T.11
Griffin, W.S.12
-
70
-
-
0032914896
-
A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease
-
A. Papassotiropoulos, M. Bagli, F. Jessen, T.A. Bayer, W. Maier, M.L. Rao and R. Heun, A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease, Ann Neurol 45 (1999), 666-668.
-
(1999)
Ann Neurol
, vol.45
, pp. 666-668
-
-
Papassotiropoulos, A.1
Bagli, M.2
Jessen, F.3
Bayer, T.A.4
Maier, W.5
Rao, M.L.6
Heun, R.7
-
71
-
-
0034278927
-
Expression of nitric oxide synthase isoforms in spinal cord in amyotrophic lateral sclerosis
-
R.K. Phul, P.J. Shaw, P.G. Ince and M.E. Smith, Expression of nitric oxide synthase isoforms in spinal cord in amyotrophic lateral sclerosis, Amyotroph Lateral Scler Other Motor Neuron Disord 1 (2000), 259-267.
-
(2000)
Amyotroph Lateral Scler Other Motor Neuron Disord
, vol.1
, pp. 259-267
-
-
Phul, R.K.1
Shaw, P.J.2
Ince, P.G.3
Smith, M.E.4
-
72
-
-
0037389393
-
A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
-
P.N. Pompl, L. Ho, M. Bianchi, T. Mcmanus, W. Gin and G.M. Pasinetti, A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis, The FASEB Journal 17 (2003), 725-727.
-
(2003)
The FASEB Journal
, vol.17
, pp. 725-727
-
-
Pompl, P.N.1
Ho, L.2
Bianchi, M.3
Mcmanus, T.4
Gin, W.5
Pasinetti, G.M.6
-
73
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
A. Pramatarova, J. Laganiere, J. Roussel, K. Brisebois and G.A. Rouleau, Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment, J Neurosci 21 (2001), 3369-3374.
-
(2001)
J Neurosci
, vol.21
, pp. 3369-3374
-
-
Pramatarova, A.1
Laganiere, J.2
Roussel, J.3
Brisebois, K.4
Rouleau, G.A.5
-
74
-
-
0035726544
-
Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse
-
X. Qiao, D.J. Cummins and S.M. Paul, Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse, Eur J Neurosci 14 (2001), 474-482.
-
(2001)
Eur J Neurosci
, vol.14
, pp. 474-482
-
-
Qiao, X.1
Cummins, D.J.2
Paul, S.M.3
-
75
-
-
0036845314
-
Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species
-
L. Qin, Y. Liu, C. Cooper, B. Liu, B. Wilson and J.S. Hong, Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species, J Neurochem 83 (2002), 973-983.
-
(2002)
J Neurochem
, vol.83
, pp. 973-983
-
-
Qin, L.1
Liu, Y.2
Cooper, C.3
Liu, B.4
Wilson, B.5
Hong, J.S.6
-
76
-
-
0034991806
-
5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease
-
T. Qu, R. Manev and H. Manev, 5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease, J Neuropsychiatry Clin Neurosci 13 (2001), 304-305.
-
(2001)
J Neuropsychiatry Clin Neurosci
, vol.13
, pp. 304-305
-
-
Qu, T.1
Manev, R.2
Manev, H.3
-
77
-
-
0028896679
-
Nonsteroidal anti-inflammatory drugs in Alzheimer's disease
-
J.B. Rich, D.X. Rasmusson, M.F. Folstein, K.A. Carson, C. Kawas and J. Brandt, Nonsteroidal anti-inflammatory drugs in Alzheimer's disease, Neurology 45 (1995), 51-55.
-
(1995)
Neurology
, vol.45
, pp. 51-55
-
-
Rich, J.B.1
Rasmusson, D.X.2
Folstein, M.F.3
Carson, K.A.4
Kawas, C.5
Brandt, J.6
-
78
-
-
0033559005
-
Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture
-
K.A. Robinson, C.A. Stewart, Q.N. Pye, X. Nguyen, L. Kenney, S. Salzman, R.A. Floyd and K. Hensley, Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture, J Neurosci Res 55 (1999), 724-732.
-
(1999)
J Neurosci Res
, vol.55
, pp. 724-732
-
-
Robinson, K.A.1
Stewart, C.A.2
Pye, Q.N.3
Nguyen, X.4
Kenney, L.5
Salzman, S.6
Floyd, R.A.7
Hensley, K.8
-
79
-
-
0026447529
-
Complement activation by beta-amyloid in Alzheimer disease
-
J. Rogers, N.R. Cooper, S. Webster, J. Schultz, P.L. McGeer, S.D. Styren, W.H. Civin, L. Brachova, B. Bradt and P. Ward, Complement activation by beta-amyloid in Alzheimer disease, Proc Natl Acad Sci USA 89 (1992), 10016-10020.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10016-10020
-
-
Rogers, J.1
Cooper, N.R.2
Webster, S.3
Schultz, J.4
McGeer, P.L.5
Styren, S.D.6
Civin, W.H.7
Brachova, L.8
Bradt, B.9
Ward, P.10
-
80
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
J. Rogers, L.C. Kirby, S.R. Hempelman, D.L. Berry, P.L. McGeer, A.W. Kaszniak, J. Zalinski, M. Cofield, L. Mansukhani and P. Willson, Clinical trial of indomethacin in Alzheimer's disease, Neurology 43 (1993), 1609-1611.
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
Berry, D.L.4
McGeer, P.L.5
Kaszniak, A.W.6
Zalinski, J.7
Cofield, M.8
Mansukhani, L.9
Willson, P.10
-
81
-
-
0344405677
-
Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration
-
C. Rozenfeld, R. Martinez, R.T. Figueiredo, M.T. Bozza, F.R. Lima, A.L. Pires, P.M. Silva, A. Bonomo, J. Lannes-Vieira, W. De Souza and V. Moura-Neto, Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration, Infect Immun 71 (2003), 2047-2057.
-
(2003)
Infect Immun
, vol.71
, pp. 2047-2057
-
-
Rozenfeld, C.1
Martinez, R.2
Figueiredo, R.T.3
Bozza, M.T.4
Lima, F.R.5
Pires, A.L.6
Silva, P.M.7
Bonomo, A.8
Lannes-Vieira, J.9
De Souza, W.10
Moura-Neto, V.11
-
82
-
-
0003012239
-
Results of a double-blind, randomized, placebo-controlled study of celecoxib in the treatment of Alzheimer's disease
-
Stockholm, April
-
S. Sainati, D. Ingram, G. Talwalker and G. Geis, Results of a double-blind, randomized, placebo-controlled study of celecoxib in the treatment of Alzheimer's disease. Sixth International Stockholm/Springfield Symposium on Advances in Alzheimer Therapy, Stockholm, April 2000.
-
(2000)
Sixth International Stockholm/Springfield Symposium on Advances in Alzheimer Therapy
-
-
Sainati, S.1
Ingram, D.2
Talwalker, G.3
Geis, G.4
-
83
-
-
0031613831
-
Leukotrienes: Lipid bioeffectors of inflammatory reactions
-
A. Sala, S. Zarini and M. Bolla, Leukotrienes: lipid bioeffectors of inflammatory reactions, Biochemistry (Mosc) 63 (1998), 84-92.
-
(1998)
Biochemistry (Mosc)
, vol.63
, pp. 84-92
-
-
Sala, A.1
Zarini, S.2
Bolla, M.3
-
84
-
-
0021321159
-
Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid, and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets
-
H. Salari, P. Braquet and P. Borgeat, Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid, and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets, Prostaglandins Leukot Med 13 (1984), 53-60.
-
(1984)
Prostaglandins Leukot Med
, vol.13
, pp. 53-60
-
-
Salari, H.1
Braquet, P.2
Borgeat, P.3
-
85
-
-
0242609178
-
Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
-
M. Sastre, I. Dewachter, G.E. Landreth, T.M. Willson, T. Klockgether, F. van Leuven and M.T. Heneka, Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase, J Neurosci 23 (2003), 9796-9804.
-
(2003)
J Neurosci
, vol.23
, pp. 9796-9804
-
-
Sastre, M.1
Dewachter, I.2
Landreth, G.E.3
Willson, T.M.4
Klockgether, T.5
Van Leuven, F.6
Heneka, M.T.7
-
86
-
-
0033551547
-
A double-blind placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease
-
S. Scharf, A. Mander, A. Ugoni, F. Vajda and N. Christophidis, A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease, Neurology 53 (1999), 197-201.
-
(1999)
Neurology
, vol.53
, pp. 197-201
-
-
Scharf, S.1
Mander, A.2
Ugoni, A.3
Vajda, F.4
Christophidis, N.5
-
87
-
-
0035877077
-
Complement activation by neurofibrillary tangles in Alzheimer's disease
-
Y. Shen, L. Lue, L. Yang, A. Roher, Y. Kuo, R. Strohmeyer, W.J. Goux, V. Lee, G.V. Johnson, S.D. Webster, N.R. Cooper, B. Bradt and J. Rogers, Complement activation by neurofibrillary tangles in Alzheimer's disease, Neurosci Lett 305 (2001), 165-168.
-
(2001)
Neurosci Lett
, vol.305
, pp. 165-168
-
-
Shen, Y.1
Lue, L.2
Yang, L.3
Roher, A.4
Kuo, Y.5
Strohmeyer, R.6
Goux, W.J.7
Lee, V.8
Johnson, G.V.9
Webster, S.D.10
Cooper, N.R.11
Bradt, B.12
Rogers, J.13
-
88
-
-
0042835437
-
Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APP-swe transgenic mice
-
J.G. Sheng, S.H. Bora, G. Xu, D.R. Borchelt, D.L. Price and V.E. Koliatsos, Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APP-swe transgenic mice, Neurobiol Dis 14 (2003), 133-145.
-
(2003)
Neurobiol Dis
, vol.14
, pp. 133-145
-
-
Sheng, J.G.1
Bora, S.H.2
Xu, G.3
Borchelt, D.R.4
Price, D.L.5
Koliatsos, V.E.6
-
89
-
-
0034879046
-
Effect of nordihydroguaiaretic acid on behavioral impairment and neuronal cell death after forebrain ischemia
-
Y. Shishido, M. Furushiro, S. Hashimoto and T. Yokokura, Effect of nordihydroguaiaretic acid on behavioral impairment and neuronal cell death after forebrain ischemia, Pharmacol Biochem Behav 69 (2001), 469-474.
-
(2001)
Pharmacol Biochem Behav
, vol.69
, pp. 469-474
-
-
Shishido, Y.1
Furushiro, M.2
Hashimoto, S.3
Yokokura, T.4
-
90
-
-
0034321972
-
Curcumin inhibits lipoxygenase by binding to its central cavity: Theoretical and X-ray evidence
-
E. Skrzypczak-Jankun, N.P. McCabe, S.H. Selman and J. Jankun, Curcumin inhibits lipoxygenase by binding to its central cavity: Theoretical and X-ray evidence, Int J Mol Med 6 (2000), 521-526.
-
(2000)
Int J Mol Med
, vol.6
, pp. 521-526
-
-
Skrzypczak-Jankun, E.1
McCabe, N.P.2
Selman, S.H.3
Jankun, J.4
-
91
-
-
0030897133
-
Risk of Alzheimer's disease and duration of NSAID use
-
W.F. Stewart, C. Kawas, M. Corrada and E.J. Metter, Risk of Alzheimer's disease and duration of NSAID use, Neurology 48 (1997), 626-632.
-
(1997)
Neurology
, vol.48
, pp. 626-632
-
-
Stewart, W.F.1
Kawas, C.2
Corrada, M.3
Metter, E.J.4
-
92
-
-
0031558654
-
Neuronal DNA damage precedes tangle formation and is associated with upregulation of nitrotyrosine in Alzheimer's disease brain
-
J.H. Su, G. Deng and C.W. Cotman, Neuronal DNA damage precedes tangle formation and is associated with upregulation of nitrotyrosine in Alzheimer's disease brain, Brain Res 774 (1997), 193-199.
-
(1997)
Brain Res
, vol.774
, pp. 193-199
-
-
Su, J.H.1
Deng, G.2
Cotman, C.W.3
-
93
-
-
0034101592
-
New antiinflammatory treatment strategy in Alzheimer's disease
-
K. Sugaya, T. Uz, V. Kumar and H. Manev, New antiinflammatory treatment strategy in Alzheimer's disease, Jpn J Pharmacol 82 (2000), 85-94.
-
(2000)
Jpn J Pharmacol
, vol.82
, pp. 85-94
-
-
Sugaya, K.1
Uz, T.2
Kumar, V.3
Manev, H.4
-
94
-
-
0037524251
-
Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis
-
E. Tamagno, M. Parola, M. Guglielmotto, G. Santoro, P. Bardini, L. Marra, M. Tabaton and O. Danni, Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis, Free Radic Biol Med 35 (2003), 45-58.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 45-58
-
-
Tamagno, E.1
Parola, M.2
Guglielmotto, M.3
Santoro, G.4
Bardini, P.5
Marra, L.6
Tabaton, M.7
Danni, O.8
-
95
-
-
0032868874
-
Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia
-
E. Tarkowski, K. Blennow, A. Wallin and A. Tarkowski, Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia, J Clin Immunol 19 (1999), 223-230.
-
(1999)
J Clin Immunol
, vol.19
, pp. 223-230
-
-
Tarkowski, E.1
Blennow, K.2
Wallin, A.3
Tarkowski, A.4
-
96
-
-
0033009113
-
Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis
-
H. Tohgi, T. Abe, K. Yamazaki, T. Murata, E. Ishizaki and C. Isobe, Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis, Ann Neurol 46 (1999), 129-131.
-
(1999)
Ann Neurol
, vol.46
, pp. 129-131
-
-
Tohgi, H.1
Abe, T.2
Yamazaki, K.3
Murata, T.4
Ishizaki, E.5
Isobe, C.6
-
97
-
-
2642693710
-
Aging associated up-regulation of neuronal 5-lipoxygenase expression: Putative role in neuronal vulnerability
-
T. Uz, C. Pesold, P. Longone and H. Manev, Aging associated up-regulation of neuronal 5-lipoxygenase expression: Putative role in neuronal vulnerability, FASEB J 12 (1998), 439-449.
-
(1998)
FASEB J
, vol.12
, pp. 439-449
-
-
Uz, T.1
Pesold, C.2
Longone, P.3
Manev, H.4
-
98
-
-
0027450057
-
Transforming growth factor-beta lis in plaques in Alzheimer's and Down pathologies
-
E.A. van der Wal, F. Gomez-Pinnilla and C.W. Cotman, Transforming growth factor-beta lis in plaques in Alzheimer's and Down pathologies, Neuroreport 4 (1993), 69-72.
-
(1993)
Neuroreport
, vol.4
, pp. 69-72
-
-
Van Der Wal, E.A.1
Gomez-Pinnilla, F.2
Cotman, C.W.3
-
99
-
-
0029971210
-
Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity
-
EL. Van Muiswinkel, R. Veerhuis and P. Eikelenboom, Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity, J Neurochem 66 (1996), 2468-2476.
-
(1996)
J Neurochem
, vol.66
, pp. 2468-2476
-
-
Van Muiswinkel, E.L.1
Veerhuis, R.2
Eikelenboom, P.3
-
100
-
-
0030978135
-
Charge-based binding of complement component Clq to the Alzheimer amyloid beta-peptide
-
S. Webster, B. Bonnell and J. Rogers, Charge-based binding of complement component Clq to the Alzheimer amyloid beta-peptide, Am J Pathol 150 (1997), 1531-1536.
-
(1997)
Am J Pathol
, vol.150
, pp. 1531-1536
-
-
Webster, S.1
Bonnell, B.2
Rogers, J.3
-
101
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity
-
S. Weggen, J.L. Eriksen, P. Das, S.A. Sagi, R. Wang, C.U. Pietrzik, K.A. Findlay, T.E. Smith, M.P. Murphy, T. Bulter, D.E. Kang, N. Marquez-Sterling, T.E. Golde and E.H. Koo, A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity, Nature 414 (2001), 212-216.
-
(2001)
Nature
, vol.414
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrzik, C.U.6
Findlay, K.A.7
Smith, T.E.8
Murphy, M.P.9
Bulter, T.10
Kang, D.E.11
Marquez-Sterling, N.12
Golde, T.E.13
Koo, E.H.14
-
102
-
-
1642292361
-
The toxicity of tumor necrosis factor-alpha upon cholinergic neurons within the nucleus basalis and the role of norepinephrine in the regulation of inflammation: Implications for Alzheimer's disease
-
G.L. Wenk, K. McGann, B. Hauss-Wegrzyniak and S. Rosi, The toxicity of tumor necrosis factor-alpha upon cholinergic neurons within the nucleus basalis and the role of norepinephrine in the regulation of inflammation: implications for Alzheimer's disease, Neuroscience 121 (2003), 719-729.
-
(2003)
Neuroscience
, vol.121
, pp. 719-729
-
-
Wenk, G.L.1
McGann, K.2
Hauss-Wegrzyniak, B.3
Rosi, S.4
-
103
-
-
0037030657
-
Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean 12-human and 15-human lipoxygenase
-
S. Whitman, M. Gezginci, B.N. Timmermann and T.R. Holman, Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean 12-human and 15-human lipoxygenase, J Med Chem 45 (2002), 2659-2666.
-
(2002)
J Med Chem
, vol.45
, pp. 2659-2666
-
-
Whitman, S.1
Gezginci, M.2
Timmermann, B.N.3
Holman, T.R.4
-
104
-
-
0035783744
-
Antiinflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia
-
A. Wong, S. Dukic-Stefanovic, J. Gasic-Milenkovic, R. Schinzel, H. Wiesinger, P. Riederer and G. Munch, Antiinflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia, Eur J Neurosci 14 (2001), 1961-1967.
-
(2001)
Eur J Neurosci
, vol.14
, pp. 1961-1967
-
-
Wong, A.1
Dukic-Stefanovic, S.2
Gasic-Milenkovic, J.3
Schinzel, R.4
Wiesinger, H.5
Riederer, P.6
Munch, G.7
-
105
-
-
0034644753
-
Tumor necrosis factor alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade
-
C.H. Woo, Y.W. Eom, M.H. Yoo, H.J. You, H.J. Han, W.K. Song, Y.J. Yoo, J.S. Chun and J.H. Kim, Tumor necrosis factor alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade, J Biol Chem 275 (2000), 32357-32362.
-
(2000)
J Biol Chem
, vol.275
, pp. 32357-32362
-
-
Woo, C.H.1
Eom, Y.W.2
Yoo, M.H.3
You, H.J.4
Han, H.J.5
Song, W.K.6
Yoo, Y.J.7
Chun, J.S.8
Kim, J.H.9
-
106
-
-
0034103604
-
Alzheimer's disease-like cerebrovascular pathology in transforming growth factor-beta 1 transgenic mice and functional metabolic correlates
-
T. Wyss-Coray, C. Lin, D. von Euw, E. Masliah, L. Mucke and P. Lacombe, Alzheimer's disease-like cerebrovascular pathology in transforming growth factor-beta 1 transgenic mice and functional metabolic correlates, Ann N Y Acad Sci 903 (2000), 317-323.
-
(2000)
Ann N Y Acad Sci
, vol.903
, pp. 317-323
-
-
Wyss-Coray, T.1
Lin, C.2
Von Euw, D.3
Masliah, E.4
Mucke, L.5
Lacombe, P.6
-
107
-
-
0029595394
-
Transcriptional Roles of Nuclear Factor B and Nuclear Factor-Interleukin-6 in the Tumor Necrosis Factor-Dependent Inducoon of Cyclooxygenase-2 in MC3T3-E1 Cells
-
K. Yamamoto, T. Arakawa, N. Ueda and S. Yamamoto, Transcriptional Roles of Nuclear Factor B and Nuclear Factor-Interleukin-6 in the Tumor Necrosis Factor-Dependent Inducoon of Cyclooxygenase-2 in MC3T3-E1 Cells, J Biol Chem 270 (1995), 31315-31320.
-
(1995)
J Biol Chem
, vol.270
, pp. 31315-31320
-
-
Yamamoto, K.1
Arakawa, T.2
Ueda, N.3
Yamamoto, S.4
-
108
-
-
0041921071
-
Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease
-
Q. Yan, J. Zhang, H. Liu, S. Babu-Khan, R. Vassar, A.L. Biere, M. Citron and Landreth, Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease, J Neurosci 23 (2003), 7504-7509.
-
(2003)
J Neurosci
, vol.23
, pp. 7504-7509
-
-
Yan, Q.1
Zhang, J.2
Liu, H.3
Babu-Khan, S.4
Vassar, R.5
Biere, A.L.6
Citron, M.7
Landreth8
-
109
-
-
0029939471
-
A gain-of-function of an amyotrophic lateral sclerosis-associated Cu, Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide
-
M.B. Yim, J.H. Kang, H.S. Yim, H.S. Kwak, P.B. Chock and E.R. Stadtman, A gain-of-function of an amyotrophic lateral sclerosis-associated Cu, Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide, Proc Natl Acad Sci USA 93 (1996), 5709-5714.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5709-5714
-
-
Yim, M.B.1
Kang, J.H.2
Yim, H.S.3
Kwak, H.S.4
Chock, P.B.5
Stadtman, E.R.6
-
110
-
-
0036269810
-
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
-
T. Yoshihara, S. Ishigaki, M. Yamamoto, Y. Liang, J. Niwa, H. Takeuchi, M. Doyu and G. Sobue, Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis, J Neurochem 80 (2002), 158-167.
-
(2002)
J Neurochem
, vol.80
, pp. 158-167
-
-
Yoshihara, T.1
Ishigaki, S.2
Yamamoto, M.3
Liang, Y.4
Niwa, J.5
Takeuchi, H.6
Doyu, M.7
Sobue, G.8
-
111
-
-
0037289757
-
The induction of the TNFalpha death domain-signaling pathway in Alzheimer's disease brain
-
M. Zhao, D.H. Cribbs, A.J. Anderson, B.J. Cummings, J.H. Su, A.J. Wasserman and C.W. Cotman, The induction of the TNFalpha death domain-signaling pathway in Alzheimer's disease brain, Neurochem Res 28 (2003), 307-318.
-
(2003)
Neurochem Res
, vol.28
, pp. 307-318
-
-
Zhao, M.1
Cribbs, D.H.2
Anderson, A.J.3
Cummings, B.J.4
Su, J.H.5
Wasserman, A.J.6
Cotman, C.W.7
|