In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid β-peptide of APP

Free Radical Biology and Medicine

Volumn 48, Issue 1, 2010, Pages 136-144

  Butterfield, D Allan ^a   Galvan, Veronica ^b   Lange, Miranda Bader ^a   Tang, Huidong ^b   Sowell, Renã A ^a   Spilman, Patricia ^b   Fombonne, Joanna ^b   Gorostiza, Olivia ^b   Zhang, Junli ^b   Sultana, Rukhsana ^a   Bredesen, Dale E ^b,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer disease; Amyloid peptide; Free radicals; In vivo oxidative stress in brain; Methionine residue; Transgenic mouse model of Alzheimer disease

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; LEUCINE; METHIONINE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MICROGLIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SENILE PLAQUE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; MALE; MAZE LEARNING; METHIONINE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDATIVE STRESS;

ANIMALIA; MAMMALIA; MUS; MUS MUSCULUS;

EID: 74149091007     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.10.035     Document Type: Article

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