메뉴 건너뛰기




Volumn 45, Issue 1, 2010, Pages 57-63

Biomarkers of inflammation and amyloid-β phagocytosis in patients at risk of Alzheimer disease

Author keywords

Alzheimer disease biomarkers; Amyloid beta; Astrocyte; Complement; Inflammation; Macrophage; Microglia; Neuron; Phagocytosis; Serum amyloid P

Indexed keywords

AMYLOID BETA PROTEIN; ANTIINFLAMMATORY AGENT; CHEMOKINE; COMPLEMENT; CYTOKINE; IMMUNOSTIMULATING AGENT; TRANSCRIPTOME;

EID: 71849103796     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2009.08.003     Document Type: Review
Times cited : (43)

References (44)
  • 4
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • Blennow K., and Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol. 2 (2003) 605-613
    • (2003) Lancet Neurol. , vol.2 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 5
    • 49049096562 scopus 로고    scopus 로고
    • Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
    • Boland B., Kumar A., Lee S., Platt F.M., Wegiel J., Yu W.H., and Nixon R.A. Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci. 28 (2008) 6926-6937
    • (2008) J. Neurosci. , vol.28 , pp. 6926-6937
    • Boland, B.1    Kumar, A.2    Lee, S.3    Platt, F.M.4    Wegiel, J.5    Yu, W.H.6    Nixon, R.A.7
  • 6
    • 28044466172 scopus 로고    scopus 로고
    • Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I
    • Carro E., Spuch C., Trejo J.L., Antequera D., and Torres-Aleman I. Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I. J. Neurosci. 25 (2005) 10884-10893
    • (2005) J. Neurosci. , vol.25 , pp. 10884-10893
    • Carro, E.1    Spuch, C.2    Trejo, J.L.3    Antequera, D.4    Torres-Aleman, I.5
  • 7
    • 0037010289 scopus 로고    scopus 로고
    • Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling
    • Colangelo V., Schurr J., Ball M.J., Pelaez R.P., Bazan N.G., and Lukiw W.J. Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling. J. Neurosci. Res. 70 (2002) 462-473
    • (2002) J. Neurosci. Res. , vol.70 , pp. 462-473
    • Colangelo, V.1    Schurr, J.2    Ball, M.J.3    Pelaez, R.P.4    Bazan, N.G.5    Lukiw, W.J.6
  • 11
    • 65649105035 scopus 로고    scopus 로고
    • Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease
    • Deane R., Bell R.D., Sagare A., and Zlokovic B.V. Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease. CNS Neurol. Disord. Drug Targets 8 (2009) 16-30
    • (2009) CNS Neurol. Disord. Drug Targets , vol.8 , pp. 16-30
    • Deane, R.1    Bell, R.D.2    Sagare, A.3    Zlokovic, B.V.4
  • 12
    • 0030250852 scopus 로고    scopus 로고
    • The role of complement and activated microglia in the pathogenesis of Alzheimer's disease
    • Eikelenboom P., and Veerhuis R. The role of complement and activated microglia in the pathogenesis of Alzheimer's disease. Neurobiol. Aging 17 (1996) 673-680
    • (1996) Neurobiol. Aging , vol.17 , pp. 673-680
    • Eikelenboom, P.1    Veerhuis, R.2
  • 13
    • 62549122091 scopus 로고    scopus 로고
    • Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly
    • Fagan A.M., Head D., Shah A.R., Marcus D., Mintun M., Morris J.C., and Holtzman D.M. Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly. Ann. Neurol. 65 (2009) 176-183
    • (2009) Ann. Neurol. , vol.65 , pp. 176-183
    • Fagan, A.M.1    Head, D.2    Shah, A.R.3    Marcus, D.4    Mintun, M.5    Morris, J.C.6    Holtzman, D.M.7
  • 14
    • 33947223454 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
    • Fagan A.M., Roe C.M., Xiong C., Mintun M.A., Morris J.C., and Holtzman D.M. Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch. Neurol. 64 (2007) 343-349
    • (2007) Arch. Neurol. , vol.64 , pp. 343-349
    • Fagan, A.M.1    Roe, C.M.2    Xiong, C.3    Mintun, M.A.4    Morris, J.C.5    Holtzman, D.M.6
  • 15
    • 33947281600 scopus 로고    scopus 로고
    • Minocycline does not affect amyloid beta phagocytosis by human microglial cells
    • Familian A., Eikelenboom P., and Veerhuis R. Minocycline does not affect amyloid beta phagocytosis by human microglial cells. Neurosci. Lett. 416 (2007) 87-91
    • (2007) Neurosci. Lett. , vol.416 , pp. 87-91
    • Familian, A.1    Eikelenboom, P.2    Veerhuis, R.3
  • 17
    • 0002314983 scopus 로고    scopus 로고
    • Macrophages infiltrate brain and express COX-2 and iNOS in Alzheimer's disease and AIDS
    • Fiala M., Liu N.Q., Reddy S., and Graves M.C. Macrophages infiltrate brain and express COX-2 and iNOS in Alzheimer's disease and AIDS. Alzheimer's Reports 4 (2001) 1-7
    • (2001) Alzheimer's Reports , vol.4 , pp. 1-7
    • Fiala, M.1    Liu, N.Q.2    Reddy, S.3    Graves, M.C.4
  • 19
    • 0037000396 scopus 로고    scopus 로고
    • Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier
    • Fiala M., Liu Q.N., Sayre J., Pop V., Brahmandam V., Graves M.C., and Vinters H.V. Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier. Eur. J. Clin. Invest. 32 (2002) 360-371
    • (2002) Eur. J. Clin. Invest. , vol.32 , pp. 360-371
    • Fiala, M.1    Liu, Q.N.2    Sayre, J.3    Pop, V.4    Brahmandam, V.5    Graves, M.C.6    Vinters, H.V.7
  • 20
    • 18144415471 scopus 로고    scopus 로고
    • Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease
    • Fox N.C., Black R.S., Gilman S., Rossor M.N., Griffith S.G., Jenkins L., and Koller M. Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease. Neurology 64 (2005) 1563-1572
    • (2005) Neurology , vol.64 , pp. 1563-1572
    • Fox, N.C.1    Black, R.S.2    Gilman, S.3    Rossor, M.N.4    Griffith, S.G.5    Jenkins, L.6    Koller, M.7
  • 21
    • 28344439699 scopus 로고    scopus 로고
    • Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease
    • Hoozemans J.J., van Haastert E.S., Veerhuis R., Arendt T., Scheper W., Eikelenboom P., and Rozemuller A.J. Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease. J. Neuroinflammation 2 (2005) 27
    • (2005) J. Neuroinflammation , vol.2 , pp. 27
    • Hoozemans, J.J.1    van Haastert, E.S.2    Veerhuis, R.3    Arendt, T.4    Scheper, W.5    Eikelenboom, P.6    Rozemuller, A.J.7
  • 22
    • 33644541112 scopus 로고    scopus 로고
    • Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology
    • Hoozemans J.J., Veerhuis R., Rozemuller J.M., and Eikelenboom P. Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology. Int. J. Dev. Neurosci. 24 (2006) 157-165
    • (2006) Int. J. Dev. Neurosci. , vol.24 , pp. 157-165
    • Hoozemans, J.J.1    Veerhuis, R.2    Rozemuller, J.M.3    Eikelenboom, P.4
  • 26
    • 0034074287 scopus 로고    scopus 로고
    • Elevation of CD69+ monocyte/macrophages in patients with Alzheimer's disease [In Process Citation]
    • Kusdra L., Rempel H., Yaffe K., and Pulliam L. Elevation of CD69+ monocyte/macrophages in patients with Alzheimer's disease [In Process Citation]. Immunobiology 202 (2000) 26-33
    • (2000) Immunobiology , vol.202 , pp. 26-33
    • Kusdra, L.1    Rempel, H.2    Yaffe, K.3    Pulliam, L.4
  • 28
    • 15944377414 scopus 로고    scopus 로고
    • Amyloid beta degradation: a challenging task for brain peptidases
    • Morelli L., Bulloj A., Leal M.C., and Castano E.M. Amyloid beta degradation: a challenging task for brain peptidases. Subcell Biochem. 38 (2005) 129-145
    • (2005) Subcell Biochem. , vol.38 , pp. 129-145
    • Morelli, L.1    Bulloj, A.2    Leal, M.C.3    Castano, E.M.4
  • 29
    • 67650741983 scopus 로고    scopus 로고
    • Binding and uptake of A beta1-42 by primary human astrocytes in vitro
    • Nielsen H.M., Veerhuis R., Holmqvist B., and Janciauskiene S. Binding and uptake of A beta1-42 by primary human astrocytes in vitro. Glia 57 (2009) 978-988
    • (2009) Glia , vol.57 , pp. 978-988
    • Nielsen, H.M.1    Veerhuis, R.2    Holmqvist, B.3    Janciauskiene, S.4
  • 31
    • 11444250354 scopus 로고    scopus 로고
    • Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study
    • Riley K.P., Snowdon D.A., Desrosiers M.F., and Markesbery W.R. Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study. Neurobiol. Aging 26 (2005) 341-347
    • (2005) Neurobiol. Aging , vol.26 , pp. 341-347
    • Riley, K.P.1    Snowdon, D.A.2    Desrosiers, M.F.3    Markesbery, W.R.4
  • 32
    • 33745252827 scopus 로고    scopus 로고
    • Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients
    • Rota E., Bellone G., Rocca P., Bergamasco B., Emanuelli G., and Ferrero P. Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients. Neurol. Sci. 27 (2006) 33-39
    • (2006) Neurol. Sci. , vol.27 , pp. 33-39
    • Rota, E.1    Bellone, G.2    Rocca, P.3    Bergamasco, B.4    Emanuelli, G.5    Ferrero, P.6
  • 34
    • 70049096490 scopus 로고    scopus 로고
    • Schuitemaker, A., Dik, M.G., Veerhuis, R., Scheltens, P., Schoonenboom, N.S., Hack, C.E., Blankenstein, M.A., Jonker, C., 2008. Inflammatory markers in AD and MCI patients with different biomarker profiles. Neurobiol. Aging. doi:10.1016/j.neurobiolaging.2008.01.014.
    • Schuitemaker, A., Dik, M.G., Veerhuis, R., Scheltens, P., Schoonenboom, N.S., Hack, C.E., Blankenstein, M.A., Jonker, C., 2008. Inflammatory markers in AD and MCI patients with different biomarker profiles. Neurobiol. Aging. doi:10.1016/j.neurobiolaging.2008.01.014.
  • 35
    • 33947287762 scopus 로고    scopus 로고
    • Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment
    • Simonsen A.H., McGuire J., Hansson O., Zetterberg H., Podust V.N., Davies H.A., Waldemar G., Minthon L., and Blennow K. Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment. Arch. Neurol. 64 (2007) 366-370
    • (2007) Arch. Neurol. , vol.64 , pp. 366-370
    • Simonsen, A.H.1    McGuire, J.2    Hansson, O.3    Zetterberg, H.4    Podust, V.N.5    Davies, H.A.6    Waldemar, G.7    Minthon, L.8    Blennow, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.