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Volumn 99, Issue 9, 2006, Pages 924-932

Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells

Author keywords

Apoptosis; Atherosclerosis; Diabetes; Electrophilic lipids; Endothelial cells; Environmental tobacco smoke; Hypertension; Mitochondria; Prostaglandins; Redox signaling; Thiols

Indexed keywords

FREE RADICAL; LIPID; NITROGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

EID: 33750475625     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000248212.86638.e9     Document Type: Review
Times cited : (290)

References (126)
  • 1
    • 0026631158 scopus 로고
    • The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis
    • Parthasarathy S, Steinberg D, Witztum JL. The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis. Annu Rev Med. 1992;43:219-225.
    • (1992) Annu Rev Med , vol.43 , pp. 219-225
    • Parthasarathy, S.1    Steinberg, D.2    Witztum, J.L.3
  • 3
    • 0036803249 scopus 로고    scopus 로고
    • Nanotransducers in cellular redox signaling: Modification of thiols by reactive oxygen and nitrogen species
    • Cooper CE, Patel RP, Brookes PS, Darley-Usmar VM. Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species. Trends Biochem Sci. 2002;27:489-492.
    • (2002) Trends Biochem Sci , vol.27 , pp. 489-492
    • Cooper, C.E.1    Patel, R.P.2    Brookes, P.S.3    Darley-Usmar, V.M.4
  • 5
    • 0348109425 scopus 로고    scopus 로고
    • Reactive oxygen species in the vasculature: Molecular and cellular mechanisms
    • Taniyama Y, Griendling KK. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension. 2003;42:1075-1081.
    • (2003) Hypertension , vol.42 , pp. 1075-1081
    • Taniyama, Y.1    Griendling, K.K.2
  • 6
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol Rev. 2002;82:47-95.
    • (2002) Physiol Rev , vol.82 , pp. 47-95
    • Droge, W.1
  • 7
    • 0033068858 scopus 로고    scopus 로고
    • Reactive oxygen species and the control of vasomotor tone
    • Somers MJ, Harrison DG. Reactive oxygen species and the control of vasomotor tone. Curr Hypertens Rep. 1999;1:102-108.
    • (1999) Curr Hypertens Rep , vol.1 , pp. 102-108
    • Somers, M.J.1    Harrison, D.G.2
  • 9
    • 0346731072 scopus 로고    scopus 로고
    • Nitric oxide and cell signaling: Modulation of redox tone and protein modification
    • Landar A, Darley-Usmar VM. Nitric oxide and cell signaling: modulation of redox tone and protein modification. Amino Acids. 2003;25:313-321.
    • (2003) Amino Acids , vol.25 , pp. 313-321
    • Landar, A.1    Darley-Usmar, V.M.2
  • 12
  • 14
    • 28444432412 scopus 로고    scopus 로고
    • Is there a future for antioxidants in atherogenesis?
    • Brigelius-Flohe R, Kluth D, Banning A. Is there a future for antioxidants in atherogenesis? Mol Nutr Food Res. 2005;49:1083-1089.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 1083-1089
    • Brigelius-Flohe, R.1    Kluth, D.2    Banning, A.3
  • 17
    • 2142695733 scopus 로고    scopus 로고
    • Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic
    • Warner TD, Mitchell JA. Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. FASEB J. 2004;18:790-804.
    • (2004) FASEB J , vol.18 , pp. 790-804
    • Warner, T.D.1    Mitchell, J.A.2
  • 18
    • 84889339053 scopus 로고    scopus 로고
    • The covalent advantage: A new paradigm for cell signaling by thiol reactive lipid oxidation products
    • Dalle-Donne I, Scalone A, Butterfield DA, eds. Indianapolis, Ind: John Wiley & Sons Inc
    • Dickinson DA, Darley-Usmar VM, Landar A. The covalent advantage: a new paradigm for cell signaling by thiol reactive lipid oxidation products. In: Dalle-Donne I, Scalone A, Butterfield DA, eds. Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases. Indianapolis, Ind: John Wiley & Sons Inc; 2006.
    • (2006) Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases
    • Dickinson, D.A.1    Darley-Usmar, V.M.2    Landar, A.3
  • 19
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol. 2004;4:181-189.
    • (2004) Nat Rev Immunol , vol.4 , pp. 181-189
    • Lambeth, J.D.1
  • 20
    • 0032930417 scopus 로고    scopus 로고
    • Mammalian nitric oxide synthases
    • Stuehr DJ. Mammalian nitric oxide synthases. Biochim Biophys Acta. 1999;1411:217-230.
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 217-230
    • Stuehr, D.J.1
  • 21
    • 28444496362 scopus 로고    scopus 로고
    • Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila
    • Mandal S, Guptan P, Owusu-Ansah E, Banerjee U. Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila. Dev Cell. 2005;9:843-854.
    • (2005) Dev Cell , vol.9 , pp. 843-854
    • Mandal, S.1    Guptan, P.2    Owusu-Ansah, E.3    Banerjee, U.4
  • 22
    • 0030774231 scopus 로고    scopus 로고
    • Differential effect of hydrogen peroxide and superoxide anion on apoptosis and proliferation of vascular smooth muscle cells
    • Li PF, Dietz R, von Harsdorf R. Differential effect of hydrogen peroxide and superoxide anion on apoptosis and proliferation of vascular smooth muscle cells. Circulation. 1997;96:3602-3609.
    • (1997) Circulation , vol.96 , pp. 3602-3609
    • Li, P.F.1    Dietz, R.2    Von Harsdorf, R.3
  • 24
    • 0034873185 scopus 로고    scopus 로고
    • Reactive oxygen species as intracellular messengers during cell growth and differentiation
    • Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem. 2001;11:173-186.
    • (2001) Cell Physiol Biochem , vol.11 , pp. 173-186
    • Sauer, H.1    Wartenberg, M.2    Hescheler, J.3
  • 25
    • 0038025936 scopus 로고    scopus 로고
    • Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia
    • Schafer M, Schafer C, Ewald N, Piper HM, Noll T. Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circ Res. 2003;92:1010-1015.
    • (2003) Circ Res , vol.92 , pp. 1010-1015
    • Schafer, M.1    Schafer, C.2    Ewald, N.3    Piper, H.M.4    Noll, T.5
  • 26
    • 0024325974 scopus 로고
    • Role of biologically modified low-density lipoprotein in atherosclerosis
    • Carew TE. Role of biologically modified low-density lipoprotein in atherosclerosis. Am J Cardiol. 1989;64:18G-22G.
    • (1989) Am J Cardiol , vol.64
    • Carew, T.E.1
  • 29
    • 0344185338 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein and 15-deoxy-Delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells
    • Ceaser EK, Ramachandran A, Levonen AL, Darley-Usmar VM. Oxidized low-density lipoprotein and 15-deoxy-Delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. Am J Physiol Heart Circ Physiol. 2003;285:H2298-H2308.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Ceaser, E.K.1    Ramachandran, A.2    Levonen, A.L.3    Darley-Usmar, V.M.4
  • 30
    • 33744972513 scopus 로고    scopus 로고
    • Mitochondrial protein oxidation and degradation in response to oxidative stress and aging
    • Bulteau AL, Szweda LI, Friguet B. Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Exp Gerontol. 2006;41:653-657.
    • (2006) Exp Gerontol , vol.41 , pp. 653-657
    • Bulteau, A.L.1    Szweda, L.I.2    Friguet, B.3
  • 31
    • 2542505678 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial DNA mutations in human aging
    • Wei YH. Oxidative stress and mitochondrial DNA mutations in human aging. Proc Soc Exp Biol Med. 1998;217:53-63.
    • (1998) Proc Soc Exp Biol Med , vol.217 , pp. 53-63
    • Wei, Y.H.1
  • 32
    • 16844369889 scopus 로고    scopus 로고
    • Nuclear and mitochondrial DNA repair: Similar pathways?
    • Larsen NB, Rasmussen M, Rasmussen LJ. Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion. 2005;5:89-108.
    • (2005) Mitochondrion , vol.5 , pp. 89-108
    • Larsen, N.B.1    Rasmussen, M.2    Rasmussen, L.J.3
  • 33
    • 18044383110 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiovascular disease
    • Ballinger SW. Mitochondrial dysfunction in cardiovascular disease. Free Radic Biol Med. 2005;38:1278-1295.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1278-1295
    • Ballinger, S.W.1
  • 34
    • 0026671245 scopus 로고
    • Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease
    • Corral-Debrinski M, Shoffner JM, Lott MT, Wallace DC. Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease. Mutat Res. 1992;275:169-180.
    • (1992) Mutat Res , vol.275 , pp. 169-180
    • Corral-Debrinski, M.1    Shoffner, J.M.2    Lott, M.T.3    Wallace, D.C.4
  • 36
    • 0035282772 scopus 로고    scopus 로고
    • How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology
    • Murphy MP. How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology. Biochim Biophys Acta. 2001;1504:1-11.
    • (2001) Biochim Biophys Acta , vol.1504 , pp. 1-11
    • Murphy, M.P.1
  • 38
    • 0032799751 scopus 로고    scopus 로고
    • Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes
    • Miro O, Alonso JR, Jarreta D, Casademont J, Urbano-Marquez A, Cardellach F. Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes. Carcinogenesis. 1999;20:1331-1336.
    • (1999) Carcinogenesis , vol.20 , pp. 1331-1336
    • Miro, O.1    Alonso, J.R.2    Jarreta, D.3    Casademont, J.4    Urbano-Marquez, A.5    Cardellach, F.6
  • 39
    • 0042736338 scopus 로고    scopus 로고
    • Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain
    • Alonso JR, Cardellach F, Lopez S, Casademont J, Miro O. Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain. Pharmacol Toxicol. 2003;93:142-146.
    • (2003) Pharmacol Toxicol , vol.93 , pp. 142-146
    • Alonso, J.R.1    Cardellach, F.2    Lopez, S.3    Casademont, J.4    Miro, O.5
  • 40
    • 0033557111 scopus 로고    scopus 로고
    • Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging - Smoking enhances oxidative stress on the aged tissues
    • Lee HC, Lim ML, Lu CY, Liu VW, Fahn HJ, Zhang C, Nagley P, Wei YH. Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging - smoking enhances oxidative stress on the aged tissues. Arch Biochem Biophys. 1999;362:309-316.
    • (1999) Arch Biochem Biophys , vol.362 , pp. 309-316
    • Lee, H.C.1    Lim, M.L.2    Lu, C.Y.3    Liu, V.W.4    Fahn, H.J.5    Zhang, C.6    Nagley, P.7    Wei, Y.H.8
  • 42
    • 31144469322 scopus 로고    scopus 로고
    • Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors
    • Desouki MM, Kulawiec M, Bansal S, Das GM, Singh KK. Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors. Cancer Biol Ther. 2005;4:1367-1373.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1367-1373
    • Desouki, M.M.1    Kulawiec, M.2    Bansal, S.3    Das, G.M.4    Singh, K.K.5
  • 43
    • 10844232037 scopus 로고    scopus 로고
    • Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in apolipoprotein E-/- mice fed a chow diet
    • Yang Z, Knight CA, Mamerow MM, Vickers K, Penn A, Postlethwait EM, Ballinger SW. Prenatal environmental tobacco smoke exposure promotes adult atherogenesis and mitochondrial damage in apolipoprotein E-/- mice fed a chow diet. Circulation. 2004;110:3715-3720.
    • (2004) Circulation , vol.110 , pp. 3715-3720
    • Yang, Z.1    Knight, C.A.2    Mamerow, M.M.3    Vickers, K.4    Penn, A.5    Postlethwait, E.M.6    Ballinger, S.W.7
  • 44
    • 0031879438 scopus 로고    scopus 로고
    • Formation and retention of cotinine during placental transfer of nicotine in human placental cotyledon
    • Sastry BV, Chance MB, Hemontolor ME, Goddijn-Wessel TA. Formation and retention of cotinine during placental transfer of nicotine in human placental cotyledon. Pharmacology. 1998;57:104-116.
    • (1998) Pharmacology , vol.57 , pp. 104-116
    • Sastry, B.V.1    Chance, M.B.2    Hemontolor, M.E.3    Goddijn-Wessel, T.A.4
  • 47
    • 24144464489 scopus 로고    scopus 로고
    • Production of reactive oxygen species in brain mitochondria: Contribution by electron transport chain and nonelectron transport chain sources
    • Adam-Vizi V. Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and nonelectron transport chain sources. Antioxid Redox Signal. 2005;7:1140-1149.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1140-1149
    • Adam-Vizi, V.1
  • 48
    • 0030969868 scopus 로고    scopus 로고
    • Superoxide production by the mitochondrial respiratory chain
    • Turrens JF. Superoxide production by the mitochondrial respiratory chain. Biosci Rep. 1997;17:3-8.
    • (1997) Biosci Rep , vol.17 , pp. 3-8
    • Turrens, J.F.1
  • 49
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • Turrens JF. Mitochondrial formation of reactive oxygen species. J Physiol. 2003;552:335-344.
    • (2003) J Physiol , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 50
    • 16844373745 scopus 로고    scopus 로고
    • Reactive oxygen species production in the mitochondrial matrix: Implications for the mechanism of mitochondrial mutation accumulation
    • de Grey AD. Reactive oxygen species production in the mitochondrial matrix: implications for the mechanism of mitochondrial mutation accumulation. Rejuvenation Res. 2005;8:13-17.
    • (2005) Rejuvenation Res , vol.8 , pp. 13-17
    • De Grey, A.D.1
  • 51
    • 9144249116 scopus 로고    scopus 로고
    • Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: Implications for mitochondrial redox regulation and antioxidant DEFENSE
    • Beer SM, Taylor ER, Brown SE, Dahm CC, Costa NJ, Runswick MJ, Murphy MP. Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE. J Biol Chem. 2004;279:47939-47951.
    • (2004) J Biol Chem , vol.279 , pp. 47939-47951
    • Beer, S.M.1    Taylor, E.R.2    Brown, S.E.3    Dahm, C.C.4    Costa, N.J.5    Runswick, M.J.6    Murphy, M.P.7
  • 53
    • 0042526012 scopus 로고    scopus 로고
    • Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes
    • Teshima Y, Akao M, Jones SP, Marban E. Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ Res. 2003;93:192-200.
    • (2003) Circ Res , vol.93 , pp. 192-200
    • Teshima, Y.1    Akao, M.2    Jones, S.P.3    Marban, E.4
  • 55
    • 3142543756 scopus 로고    scopus 로고
    • Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: Protective role of endogenous nitric oxide
    • Matsunaga T, Kotamraju S, Kalivendi SV, Dhanasekaran A, Joseph J, Kalyanaraman B. Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: protective role of endogenous nitric oxide. J Biol Chem. 2004;279:28614-28624.
    • (2004) J Biol Chem , vol.279 , pp. 28614-28624
    • Matsunaga, T.1    Kotamraju, S.2    Kalivendi, S.V.3    Dhanasekaran, A.4    Joseph, J.5    Kalyanaraman, B.6
  • 56
    • 0037033039 scopus 로고    scopus 로고
    • Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants
    • Echtay KS, Murphy MP, Smith RA, Talbot DA, Brand MD. Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants. J Biol Chem. 2002;277:47129-47135.
    • (2002) J Biol Chem , vol.277 , pp. 47129-47135
    • Echtay, K.S.1    Murphy, M.P.2    Smith, R.A.3    Talbot, D.A.4    Brand, M.D.5
  • 58
    • 4043161974 scopus 로고    scopus 로고
    • Mitochondrial redox control of matrix metalloproteinases
    • Nelson KK, Melendez JA. Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med. 2004;37:768-784.
    • (2004) Free Radic Biol Med , vol.37 , pp. 768-784
    • Nelson, K.K.1    Melendez, J.A.2
  • 59
    • 0037907756 scopus 로고    scopus 로고
    • Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain
    • Chang SH, Garcia J, Melendez JA, Kilberg MS, Agarwal A. Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain. Biochem J. 2003;371:877-885.
    • (2003) Biochem J , vol.371 , pp. 877-885
    • Chang, S.H.1    Garcia, J.2    Melendez, J.A.3    Kilberg, M.S.4    Agarwal, A.5
  • 60
    • 4344716628 scopus 로고    scopus 로고
    • Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines
    • Gurgul E, Lortz S, Tiedge M, Jorns A, Lenzen S. Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines. Diabetes. 2004;53:2271-2280.
    • (2004) Diabetes , vol.53 , pp. 2271-2280
    • Gurgul, E.1    Lortz, S.2    Tiedge, M.3    Jorns, A.4    Lenzen, S.5
  • 62
    • 0032738983 scopus 로고    scopus 로고
    • Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase
    • Go YM, Patel RP, Maland MC, Park H, Beckman JS, Darley-Usmar VM, Jo H. Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase. Am J Physiol. 1999;277:H1647-H1653.
    • (1999) Am J Physiol , vol.277
    • Go, Y.M.1    Patel, R.P.2    Maland, M.C.3    Park, H.4    Beckman, J.S.5    Darley-Usmar, V.M.6    Jo, H.7
  • 63
    • 0141706665 scopus 로고    scopus 로고
    • Activation of 5′-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite
    • Zou MH, Hou XY, Shi CM, Kirkpatick S, Liu F, Goldman MH, Cohen RA. Activation of 5′-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. J Biol Chem. 2003;278:34003-34010.
    • (2003) J Biol Chem , vol.278 , pp. 34003-34010
    • Zou, M.H.1    Hou, X.Y.2    Shi, C.M.3    Kirkpatick, S.4    Liu, F.5    Goldman, M.H.6    Cohen, R.A.7
  • 69
    • 14044250955 scopus 로고    scopus 로고
    • Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport
    • Shao B, Bergt C, Fu X, Green P, Voss JC, Oda MN, Oram JF, Heinecke JW. Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport. J Biol Chem. 2005;280:5983-5993.
    • (2005) J Biol Chem , vol.280 , pp. 5983-5993
    • Shao, B.1    Bergt, C.2    Fu, X.3    Green, P.4    Voss, J.C.5    Oda, M.N.6    Oram, J.F.7    Heinecke, J.W.8
  • 71
    • 19644368345 scopus 로고    scopus 로고
    • Nitric oxide: Orchestrating hypoxia regulation through mitochondrial respiration and the endoplasmic reticulum stress response
    • Xu W, Charles IG, Moncada S. Nitric oxide: orchestrating hypoxia regulation through mitochondrial respiration and the endoplasmic reticulum stress response. Cell Res. 2005;15:63-65.
    • (2005) Cell Res , vol.15 , pp. 63-65
    • Xu, W.1    Charles, I.G.2    Moncada, S.3
  • 72
    • 0345731024 scopus 로고    scopus 로고
    • Control of the nitric oxide-cytochrome c oxidase signaling pathway under pathological and physiological conditions
    • Shiva S, Darley-Usmar VM. Control of the nitric oxide-cytochrome c oxidase signaling pathway under pathological and physiological conditions. IUBMB Life. 2003;55:585-590.
    • (2003) IUBMB Life , vol.55 , pp. 585-590
    • Shiva, S.1    Darley-Usmar, V.M.2
  • 73
    • 11144356896 scopus 로고    scopus 로고
    • Docking of endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane: A pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria
    • Gao S, Chen J, Brodsky SV, Huang H, Adler S, Lee JH, Dhadwal N, Cohen-Gould L, Gross SS, Goligorsky MS. Docking of endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane: a pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria. J Biol Chem. 2004;279:15968-15974.
    • (2004) J Biol Chem , vol.279 , pp. 15968-15974
    • Gao, S.1    Chen, J.2    Brodsky, S.V.3    Huang, H.4    Adler, S.5    Lee, J.H.6    Dhadwal, N.7    Cohen-Gould, L.8    Gross, S.S.9    Goligorsky, M.S.10
  • 74
    • 0742323115 scopus 로고    scopus 로고
    • Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells
    • Dedkova EN, Ji X, Lipsius SL, Blatter LA. Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells. Am J Physiol Cell Physiol. 2004;286:C406-C415.
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Dedkova, E.N.1    Ji, X.2    Lipsius, S.L.3    Blatter, L.A.4
  • 75
    • 10244222287 scopus 로고    scopus 로고
    • Mitochondrial nitric-oxide synthase: Enzyme expression, characterization, and regulation
    • Haynes V, Elfering S, Traaseth N, Giulivi C. Mitochondrial nitric-oxide synthase: enzyme expression, characterization, and regulation. J Bioenerg Biomembr. 2004;36:341-346.
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 341-346
    • Haynes, V.1    Elfering, S.2    Traaseth, N.3    Giulivi, C.4
  • 76
    • 0347747971 scopus 로고    scopus 로고
    • Changes in NO bioavailability regulate cardiac O2 consumption: Control by intramitochondrial SOD2 and intracellular myoglobin
    • Li W, Jue T, Edwards J, Wang X, Hintze TH. Changes in NO bioavailability regulate cardiac O2 consumption: control by intramitochondrial SOD2 and intracellular myoglobin. Am J Physiol Heart Circ Physiol. 2004;286:H47-H54.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Li, W.1    Jue, T.2    Edwards, J.3    Wang, X.4    Hintze, T.H.5
  • 78
    • 0035793178 scopus 로고    scopus 로고
    • The biological lifetime of nitric oxide: Implications for the perivascular dynamics of NO and O2
    • Thomas DD, Liu X, Kantrow SP, Lancaster JR Jr. The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2. Proc Natl Acad Sci U S A. 2001;98:355-360.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 355-360
    • Thomas, D.D.1    Liu, X.2    Kantrow, S.P.3    Lancaster Jr., J.R.4
  • 79
    • 0036513249 scopus 로고    scopus 로고
    • Does nitric oxide modulate mitochondrial energy generation and apoptosis?
    • Moncada S, Erusalimsky JD. Does nitric oxide modulate mitochondrial energy generation and apoptosis? Nat Rev Mol Cell Biol. 2002;3:214-220.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 214-220
    • Moncada, S.1    Erusalimsky, J.D.2
  • 83
    • 33645806282 scopus 로고    scopus 로고
    • S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells
    • Clavreul N, Adachi T, Pimental DR, Ido Y, Schoneich C, Cohen RA. S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells. FASEB J. 2006;20:518-520.
    • (2006) FASEB J , vol.20 , pp. 518-520
    • Clavreul, N.1    Adachi, T.2    Pimental, D.R.3    Ido, Y.4    Schoneich, C.5    Cohen, R.A.6
  • 84
    • 33646573080 scopus 로고    scopus 로고
    • Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells
    • Xie Z, Dong Y, Zhang M, Cui MZ, Cohen RA, Riek U, Neumann D, Schlattner U, Zou MH. Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells. J Biol Chem. 2006;281:6366-6375.
    • (2006) J Biol Chem , vol.281 , pp. 6366-6375
    • Xie, Z.1    Dong, Y.2    Zhang, M.3    Cui, M.Z.4    Cohen, R.A.5    Riek, U.6    Neumann, D.7    Schlattner, U.8    Zou, M.H.9
  • 85
    • 20944442518 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II
    • Kimura S, Zhang GX, Nishiyama A, Shokoji T, Yao L, Fan YY, Rahman M, Suzuki T, Maeta H, Abe Y. Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II. Hypertension. 2005;45:860-866.
    • (2005) Hypertension , vol.45 , pp. 860-866
    • Kimura, S.1    Zhang, G.X.2    Nishiyama, A.3    Shokoji, T.4    Yao, L.5    Fan, Y.Y.6    Rahman, M.7    Suzuki, T.8    Maeta, H.9    Abe, Y.10
  • 86
    • 1542298924 scopus 로고    scopus 로고
    • Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF
    • Krieg T, Cui L, Qin Q, Cohen MV, Downey JM. Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF. J Mol Cell Cardiol. 2004;36:435-443.
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 435-443
    • Krieg, T.1    Cui, L.2    Qin, Q.3    Cohen, M.V.4    Downey, J.M.5
  • 87
    • 0035078341 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (beta) in fetal hepatocytes
    • Herrera B, Alvarez AM, Sanchez A, Fernandez M, Roncero C, Benito M, Fabregat I. Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (beta) in fetal hepatocytes. FASEB J. 2001;15:741-751.
    • (2001) FASEB J , vol.15 , pp. 741-751
    • Herrera, B.1    Alvarez, A.M.2    Sanchez, A.3    Fernandez, M.4    Roncero, C.5    Benito, M.6    Fabregat, I.7
  • 89
    • 0032783530 scopus 로고    scopus 로고
    • Mitochondrial glutathione modulates TNF-alpha-induced endothelial cell dysfunction
    • Chen KH, Reece LM, Leary JF. Mitochondrial glutathione modulates TNF-alpha-induced endothelial cell dysfunction. Free Radic Biol Med. 1999;27:100-109.
    • (1999) Free Radic Biol Med , vol.27 , pp. 100-109
    • Chen, K.H.1    Reece, L.M.2    Leary, J.F.3
  • 90
    • 4544225647 scopus 로고    scopus 로고
    • Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling
    • Chen K, Thomas SR, Albano A, Murphy MP, Keaney JF Jr. Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem. 2004;279:35079-35086.
    • (2004) J Biol Chem , vol.279 , pp. 35079-35086
    • Chen, K.1    Thomas, S.R.2    Albano, A.3    Murphy, M.P.4    Keaney Jr., J.F.5
  • 91
    • 0033826520 scopus 로고    scopus 로고
    • Role for mitochondrial oxidants as regulators of cellular metabolism
    • Nemoto S, Takeda K, Yu ZX, Ferrans VJ, Finkel T. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000;20:7311-7318.
    • (2000) Mol Cell Biol , vol.20 , pp. 7311-7318
    • Nemoto, S.1    Takeda, K.2    Yu, Z.X.3    Ferrans, V.J.4    Finkel, T.5
  • 92
    • 14644418500 scopus 로고    scopus 로고
    • Mitochondria-derived reactive oxygen species and vascular MAP kinases: Comparison of angiotensin II and diazoxide
    • Kimura S, Zhang GX, Nishiyama A, Shokoji T, Yao L, Fan YY, Rahman M, Abe Y. Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide. Hypertension. 2005;45:438-444.
    • (2005) Hypertension , vol.45 , pp. 438-444
    • Kimura, S.1    Zhang, G.X.2    Nishiyama, A.3    Shokoji, T.4    Yao, L.5    Fan, Y.Y.6    Rahman, M.7    Abe, Y.8
  • 93
    • 0037127305 scopus 로고    scopus 로고
    • Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response
    • Chang SH, Barbosa-Tessmann I, Chen C, Kilberg MS, Agarwal A. Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response. J Biol Chem. 2002;277:1933-1940.
    • (2002) J Biol Chem , vol.277 , pp. 1933-1940
    • Chang, S.H.1    Barbosa-Tessmann, I.2    Chen, C.3    Kilberg, M.S.4    Agarwal, A.5
  • 94
    • 0346093889 scopus 로고    scopus 로고
    • A radical explanation for glucose-induced beta cell dysfunction
    • Brownlee M. A radical explanation for glucose-induced beta cell dysfunction. J Clin Invest. 2003;112:1788-1790.
    • (2003) J Clin Invest , vol.112 , pp. 1788-1790
    • Brownlee, M.1
  • 95
    • 28044432087 scopus 로고    scopus 로고
    • Role of nitric oxide in diabetic complications
    • Cohen RA. Role of nitric oxide in diabetic complications. Am J Ther. 2005;12:499-502.
    • (2005) Am J Ther , vol.12 , pp. 499-502
    • Cohen, R.A.1
  • 96
    • 33746750605 scopus 로고    scopus 로고
    • Maternally transmitted diabetes mellitus associated with the mitochondrial tRNA(Leu(UUR)) A3243G mutation in a four-generation Han Chinese family
    • Lu J, Wang D, Li R, Li W, Ji J, Zhao J, Ye W, Yang L, Qian Y, Zhu Y, Guan MX. Maternally transmitted diabetes mellitus associated with the mitochondrial tRNA(Leu(UUR)) A3243G mutation in a four-generation Han Chinese family. Biochem Biophys Res Commun. 2006;348:115-119.
    • (2006) Biochem Biophys Res Commun , vol.348 , pp. 115-119
    • Lu, J.1    Wang, D.2    Li, R.3    Li, W.4    Ji, J.5    Zhao, J.6    Ye, W.7    Yang, L.8    Qian, Y.9    Zhu, Y.10    Guan, M.X.11
  • 97
    • 33745779229 scopus 로고    scopus 로고
    • Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function
    • de Andrade PB, Rubi B, Frigerio F, van den Ouweland JM, Maassen JA, Maechler P. Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function. Diabetologia. 2006;49:1816-1826.
    • (2006) Diabetologia , vol.49 , pp. 1816-1826
    • De Andrade, P.B.1    Rubi, B.2    Frigerio, F.3    Van Den Ouweland, J.M.4    Maassen, J.A.5    Maechler, P.6
  • 99
    • 33645765312 scopus 로고    scopus 로고
    • Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
    • Rolo AP, Palmeira CM. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol. 2006;212:167-178.
    • (2006) Toxicol Appl Pharmacol , vol.212 , pp. 167-178
    • Rolo, A.P.1    Palmeira, C.M.2
  • 100
    • 0842328003 scopus 로고    scopus 로고
    • Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes
    • Green K, Brand MD, Murphy MP. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes. 2004;53(suppl 1):S110-S118.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Green, K.1    Brand, M.D.2    Murphy, M.P.3
  • 102
  • 103
    • 33744465025 scopus 로고    scopus 로고
    • Mitochondria damage checkpoint, aging, and cancer
    • Singh KK. Mitochondria damage checkpoint, aging, and cancer. Ann N Y Acad Sci. 2006;1067:182-190.
    • (2006) Ann N Y Acad Sci , vol.1067 , pp. 182-190
    • Singh, K.K.1
  • 104
    • 32544443022 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human neoplasia
    • Czarnecka AM, Golik P, Bartnik E. Mitochondrial DNA mutations in human neoplasia. J Appl Genet. 2006;47:67-78.
    • (2006) J Appl Genet , vol.47 , pp. 67-78
    • Czarnecka, A.M.1    Golik, P.2    Bartnik, E.3
  • 105
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004;84:1381-1478.
    • (2004) Physiol Rev , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney Jr., J.F.2
  • 107
    • 0035750333 scopus 로고    scopus 로고
    • Heme oxygenase as an intrinsic defense system in vascular wall: Implication against atherogenesis
    • Ishikawa K, Maruyama Y. Heme oxygenase as an intrinsic defense system in vascular wall: implication against atherogenesis. J Atheroscler Thromb. 2001;8:63-70.
    • (2001) J Atheroscler Thromb , vol.8 , pp. 63-70
    • Ishikawa, K.1    Maruyama, Y.2
  • 108
    • 0037084283 scopus 로고    scopus 로고
    • Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: Protection against quinone-mediated oxidative stress
    • Moellering DR, Levonen AL, Go YM, Patel RP, Dickinson DA, Forman HJ, Darley-Usmar VM. Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress. Biochem J. 2002;362:51-59.
    • (2002) Biochem J , vol.362 , pp. 51-59
    • Moellering, D.R.1    Levonen, A.L.2    Go, Y.M.3    Patel, R.P.4    Dickinson, D.A.5    Forman, H.J.6    Darley-Usmar, V.M.7
  • 109
    • 0037423812 scopus 로고    scopus 로고
    • Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements
    • Bea F, Hudson FN, Chait A, Kavanagh TJ, Rosenfeld ME. Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements. Circ Res. 2003;92:386-393.
    • (2003) Circ Res , vol.92 , pp. 386-393
    • Bea, F.1    Hudson, F.N.2    Chait, A.3    Kavanagh, T.J.4    Rosenfeld, M.E.5
  • 110
    • 0142012164 scopus 로고    scopus 로고
    • Detoxification of electrophilic compounds by glutathione S-transferase catalysis: Determinants of individual response to chemical carcinogens and chemotherapeutic drugs?
    • Coles BF, Kadlubar FF. Detoxification of electrophilic compounds by glutathione S-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs? Biofactors. 2003;17:115-130.
    • (2003) Biofactors , vol.17 , pp. 115-130
    • Coles, B.F.1    Kadlubar, F.F.2
  • 111
    • 0037454012 scopus 로고    scopus 로고
    • Association of polymorphism in glutamatecysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction
    • Koide S, Kugiyama K, Sugiyama S, Nakamura S, Fukushima H, Honda O, Yoshimura M, Ogawa H. Association of polymorphism in glutamatecysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction. J Am Coll Cardiol. 2003;41:539-545.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 539-545
    • Koide, S.1    Kugiyama, K.2    Sugiyama, S.3    Nakamura, S.4    Fukushima, H.5    Honda, O.6    Yoshimura, M.7    Ogawa, H.8
  • 114
    • 0035078313 scopus 로고    scopus 로고
    • Increased DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype
    • Izzotti A, Cartiglia C, Lewtas J, De Flora S. Increased DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype. FASEB J. 2001;15:752-757.
    • (2001) FASEB J , vol.15 , pp. 752-757
    • Izzotti, A.1    Cartiglia, C.2    Lewtas, J.3    De Flora, S.4
  • 120
    • 0037155868 scopus 로고    scopus 로고
    • 15-Deoxy-Delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes
    • Shibata T, Kondo M, Osawa T, Shibata N, Kobayashi M, Uchida K. 15-Deoxy-Delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. J Biol Chem. 2002;277:10459-10466.
    • (2002) J Biol Chem , vol.277 , pp. 10459-10466
    • Shibata, T.1    Kondo, M.2    Osawa, T.3    Shibata, N.4    Kobayashi, M.5    Uchida, K.6
  • 121
    • 0041922325 scopus 로고    scopus 로고
    • The isoprostanes: Unique products of arachidonic acid oxidation-a review
    • Fam SS, Morrow JD. The isoprostanes: unique products of arachidonic acid oxidation-a review. Curr Med Chem. 2003;10:1723-1740.
    • (2003) Curr Med Chem , vol.10 , pp. 1723-1740
    • Fam, S.S.1    Morrow, J.D.2
  • 122
    • 0037428454 scopus 로고    scopus 로고
    • Electrophilic prostaglandins and lipid aldehydes repress redox sensitive transcription factors p53 and HIF by impairing the selenoprotein thioredoxin reductase
    • Moos PJ, Edes K, Cassidy P, Massuda E, Fitzpatrick FA. Electrophilic prostaglandins and lipid aldehydes repress redox sensitive transcription factors p53 and HIF by impairing the selenoprotein thioredoxin reductase. J Biol Chem. 2003;278:745-750.
    • (2003) J Biol Chem , vol.278 , pp. 745-750
    • Moos, P.J.1    Edes, K.2    Cassidy, P.3    Massuda, E.4    Fitzpatrick, F.A.5
  • 124
    • 33645459848 scopus 로고    scopus 로고
    • Identification of novel protein targets for modification by 15-deoxy-delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton
    • Stamatakis K, Sanchez-Gomez FJ, Perez-Sala D. Identification of novel protein targets for modification by 15-deoxy-delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton. J Am Soc Nephrol. 2006;17:89-98.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 89-98
    • Stamatakis, K.1    Sanchez-Gomez, F.J.2    Perez-Sala, D.3
  • 125
    • 0038342017 scopus 로고    scopus 로고
    • Oxidative stress, exercise, and antioxidant supplementation
    • Urso ML, Clarkson PM. Oxidative stress, exercise, and antioxidant supplementation. Toxicology. 2003;189:41-54.
    • (2003) Toxicology , vol.189 , pp. 41-54
    • Urso, M.L.1    Clarkson, P.M.2


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