-
1
-
-
20244364226
-
Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice
-
12020956 10.1016/S0165-5728(02)00050-4 1:CAS:528:DC%2BD38XjvVaqtrY%3D
-
N Abbas I Bednar E Mix S Marie D Paterson A Ljungberg C Morris B Winblad A Nordberg J Zhu 2002 Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice J Neuroimmunol 126 50 57 12020956 10.1016/S0165-5728(02)00050-4 1:CAS:528:DC%2BD38XjvVaqtrY%3D
-
(2002)
J Neuroimmunol
, vol.126
, pp. 50-57
-
-
Abbas, N.1
Bednar, I.2
Mix, E.3
Marie, S.4
Paterson, D.5
Ljungberg, A.6
Morris, C.7
Winblad, B.8
Nordberg, A.9
Zhu, J.10
-
2
-
-
0038452658
-
Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity
-
12832532 1:CAS:528:DC%2BD3sXltlent7s%3D
-
AY Abramov L Canevari MR Duchen 2003 Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity J Neurosci 23 5088 5095 12832532 1:CAS:528:DC%2BD3sXltlent7s%3D
-
(2003)
J Neurosci
, vol.23
, pp. 5088-5095
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
3
-
-
34249058674
-
Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial
-
ADAPT Research Group. 17460158 10.1212/01.wnl.0000260269.93245.d2 1:CAS:528:DC%2BD2sXltl2itrY%3D
-
ADAPT Research Group CG Lyketsos JC Breitner RC Green BK Martin C Meinert S Piantadosi M Sabbagh 2007 Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial Neurology 68 1800 1808 17460158 10.1212/01.wnl.0000260269.93245.d2 1:CAS:528:DC%2BD2sXltl2itrY%3D
-
(2007)
Neurology
, vol.68
, pp. 1800-1808
-
-
Lyketsos, C.G.1
Breitner, J.C.2
Green, R.C.3
Martin, B.K.4
Meinert, C.5
Piantadosi, S.6
Sabbagh, M.7
-
4
-
-
0037475148
-
In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malono nitrile
-
12617976 10.1016/S0306-4522(02)00907-7 1:CAS:528:DC%2BD3sXhs1KhsrY%3D
-
ED Agdeppa V Kepe A Petri N Satyamurthy J Liu SC Huang GW Small GM Cole JR Barrio 2003 In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2- naphthyl]ethylidene)malono nitrile Neuroscience 117 723 730 12617976 10.1016/S0306-4522(02)00907-7 1:CAS:528:DC%2BD3sXhs1KhsrY%3D
-
(2003)
Neuroscience
, vol.117
, pp. 723-730
-
-
Agdeppa, E.D.1
Kepe, V.2
Petri, A.3
Satyamurthy, N.4
Liu, J.5
Huang, S.C.6
Small, G.W.7
Cole, G.M.8
Barrio, J.R.9
-
5
-
-
36448994709
-
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
-
18026097 10.1038/nn2014 1:CAS:528:DC%2BD2sXhtlKltLbP
-
B Ajami JL Bennett C Krieger W Tetzlaff FM Rossi 2007 Local self-renewal can sustain CNS microglia maintenance and function throughout adult life Nat Neurosci 10 1538 1543 18026097 10.1038/nn2014 1:CAS:528:DC%2BD2sXhtlKltLbP
-
(2007)
Nat Neurosci
, vol.10
, pp. 1538-1543
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
Tetzlaff, W.4
Rossi, F.M.5
-
6
-
-
0034081386
-
Lower counts of astroglia and activated microglia in patients with Alzheimer's disease with regular use of non-steroidal anti-inflammatory drugs
-
12214109 1:CAS:528:DC%2BD3MXkslOrtg%3D%3D
-
I Alafuzoff M Overmyer S Helisalmi H Soininen 2000 Lower counts of astroglia and activated microglia in patients with Alzheimer's disease with regular use of non-steroidal anti-inflammatory drugs J Alzheimers Dis 2 37 46 12214109 1:CAS:528:DC%2BD3MXkslOrtg%3D%3D
-
(2000)
J Alzheimers Dis
, vol.2
, pp. 37-46
-
-
Alafuzoff, I.1
Overmyer, M.2
Helisalmi, S.3
Soininen, H.4
-
7
-
-
77749336627
-
Amyloid-{beta} aggregates cause alterations of astrocytic metabolic phenotype: Impact on neuronal viability
-
20203192 10.1523/JNEUROSCI.5098-09.2010 1:CAS:528:DC%2BC3cXjtFahtbY%3D
-
I Allaman M Gavillet M Belanger T Laroche D Viertl HA Lashuel PJ Magistretti 2010 Amyloid-{beta} aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability J Neurosci 30 3326 3338 20203192 10.1523/JNEUROSCI.5098-09.2010 1:CAS:528:DC%2BC3cXjtFahtbY%3D
-
(2010)
J Neurosci
, vol.30
, pp. 3326-3338
-
-
Allaman, I.1
Gavillet, M.2
Belanger, M.3
Laroche, T.4
Viertl, D.5
Lashuel, H.A.6
Magistretti, P.J.7
-
8
-
-
0033018506
-
Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
10349851 10.1046/j.1471-4159.1999.0722415.x 1:CAS:528:DyaK1MXjsV2hsLs%3D
-
G Almer S Vukosavic N Romero S Przedborski 1999 Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis J Neurochem 72 2415 2425 10349851 10.1046/j.1471-4159.1999. 0722415.x 1:CAS:528:DyaK1MXjsV2hsLs%3D
-
(1999)
J Neurochem
, vol.72
, pp. 2415-2425
-
-
Almer, G.1
Vukosavic, S.2
Romero, N.3
Przedborski, S.4
-
9
-
-
0035132167
-
Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
-
11220737 10.1002/1531-8249(20010201)49:2 <176::AID-ANA37>3.0.CO;2-X 1:CAS:528:DC%2BD3MXhsVymur4%3D
-
G Almer C Guegan P Teismann A Naini G Rosoklija AP Hays C Chen S Przedborski 2001 Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis Ann Neurol 49 176 185 11220737 10.1002/1531-8249(20010201)49:2<176::AID-ANA37>3.0.CO;2-X 1:CAS:528:DC%2BD3MXhsVymur4%3D
-
(2001)
Ann Neurol
, vol.49
, pp. 176-185
-
-
Almer, G.1
Guegan, C.2
Teismann, P.3
Naini, A.4
Rosoklija, G.5
Hays, A.P.6
Chen, C.7
Przedborski, S.8
-
10
-
-
0026760984
-
Production of hemolymphopoietic cytokines (Il-6, Il-8, colony-stimulating factors) by normal human astrocytes in response to Il-1-beta and tumor-necrosis-factor-alpha
-
1382099 1:CAS:528:DyaK3sXitVKqtQ%3D%3D
-
F Aloisi A Care G Borsellino P Gallo S Rosa A Bassani A Cabibbo U Testa G Levi C Peschle 1992 Production of hemolymphopoietic cytokines (Il-6, Il-8, colony-stimulating factors) by normal human astrocytes in response to Il-1-beta and tumor-necrosis-factor-alpha J Immunol 149 2358 2366 1382099 1:CAS:528:DyaK3sXitVKqtQ%3D%3D
-
(1992)
J Immunol
, vol.149
, pp. 2358-2366
-
-
Aloisi, F.1
Care, A.2
Borsellino, G.3
Gallo, P.4
Rosa, S.5
Bassani, A.6
Cabibbo, A.7
Testa, U.8
Levi, G.9
Peschle, C.10
-
11
-
-
0033029151
-
TGF-beta(1), regulation of Alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: MRNA stabilization
-
10407185 10.1016/S0169-328X(99)00158-8 1:CAS:528:DyaK1MXks1Ghtro%3D
-
FM Amara A Junaid RR Clough BH Liang 1999 TGF-beta(1), regulation of Alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization Mol Brain Res 71 42 49 10407185 10.1016/S0169-328X(99)00158-8 1:CAS:528:DyaK1MXks1Ghtro%3D
-
(1999)
Mol Brain Res
, vol.71
, pp. 42-49
-
-
Amara, F.M.1
Junaid, A.2
Clough, R.R.3
Liang, B.H.4
-
12
-
-
0034643832
-
Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists: The Cache County study
-
10851364 1:CAS:528:DC%2BD3cXksVGisr8%3D
-
JC Anthony JC Breitner PP Zandi MR Meyer I Jurasova MC Norton SV Stone 2000 Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists: the Cache County study Neurology 54 2066 2071 10851364 1:CAS:528: DC%2BD3cXksVGisr8%3D
-
(2000)
Neurology
, vol.54
, pp. 2066-2071
-
-
Anthony, J.C.1
Breitner, J.C.2
Zandi, P.P.3
Meyer, M.R.4
Jurasova, I.5
Norton, M.C.6
Stone, S.V.7
-
13
-
-
0035831189
-
Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
-
11245811 10.1016/S0006-8993(00)03176-0 1:CAS:528:DC%2BD3MXhs1eitrk%3D
-
J Apelt R Schliebs 2001 Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology Brain Res 894 21 30 11245811 10.1016/S0006-8993(00)03176-0 1:CAS:528:DC%2BD3MXhs1eitrk%3D
-
(2001)
Brain Res
, vol.894
, pp. 21-30
-
-
Apelt, J.1
Schliebs, R.2
-
14
-
-
0034932973
-
C-terminal fragment of amyloid precursor protein induces astrocytosis
-
11432978 10.1046/j.1471-4159.2001.00370.x 1:CAS:528:DC%2BD3MXltVymu7s%3D
-
JH Bach HS Chae JC Rah MW Lee CH Park SH Choi JK Choi SH Lee YS Kim KY Kim WB Lee YH Suh SS Kim 2001 C-terminal fragment of amyloid precursor protein induces astrocytosis J Neurochem 78 109 120 11432978 10.1046/j.1471-4159.2001. 00370.x 1:CAS:528:DC%2BD3MXltVymu7s%3D
-
(2001)
J Neurochem
, vol.78
, pp. 109-120
-
-
Bach, J.H.1
Chae, H.S.2
Rah, J.C.3
Lee, M.W.4
Park, C.H.5
Choi, S.H.6
Choi, J.K.7
Lee, S.H.8
Kim, Y.S.9
Kim, K.Y.10
Lee, W.B.11
Suh, Y.H.12
Kim, S.S.13
-
15
-
-
0033213637
-
PPAR gamma is required for placental, cardiac, and adipose tissue development
-
10549290 10.1016/S1097-2765(00)80209-9 1:CAS:528:DyaK1MXntFCgsLY%3D
-
Y Barak MC Nelson ES Ong YZ Jones P Ruiz-Lozano KR Chien A Koder RM Evans 1999 PPAR gamma is required for placental, cardiac, and adipose tissue development Mol Cell 4 585 595 10549290 10.1016/S1097-2765(00)80209-9 1:CAS:528:DyaK1MXntFCgsLY%3D
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.M.8
-
16
-
-
0030610645
-
Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein e
-
9278049 10.1038/42257 1:CAS:528:DyaK2sXlslagsrY%3D
-
SW Barger AD Harmon 1997 Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E Nature 388 878 881 9278049 10.1038/42257 1:CAS:528:DyaK2sXlslagsrY%3D
-
(1997)
Nature
, vol.388
, pp. 878-881
-
-
Barger, S.W.1
Harmon, A.D.2
-
17
-
-
0027421612
-
Beta-amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimers-disease
-
1:CAS:528:DyaK2cXltFaltQ%3D%3D
-
SW Barger VL Smithswintosky RE Rydel MP Mattson 1993 Beta-amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimers-disease Alzheimers Dis: Amyloid Precusor Proteins, Signal Transduct, Neuronal Transplant 695 158 164 1:CAS:528:DyaK2cXltFaltQ%3D%3D
-
(1993)
Alzheimers Dis: Amyloid Precusor Proteins, Signal Transduct, Neuronal Transplant
, vol.695
, pp. 158-164
-
-
Barger, S.W.1
Smithswintosky, V.L.2
Rydel, R.E.3
Mattson, M.P.4
-
18
-
-
0029033167
-
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: Evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation
-
7568127 10.1073/pnas.92.20.9328 1:CAS:528:DyaK2MXosVWltbg%3D
-
SW Barger D Horster K Furukawa Y Goodman J Krieglstein MP Mattson 1995 Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation Proc Natl Acad Sci USA 92 9328 9332 7568127 10.1073/pnas.92.20.9328 1:CAS:528:DyaK2MXosVWltbg%3D
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9328-9332
-
-
Barger, S.W.1
Horster, D.2
Furukawa, K.3
Goodman, Y.4
Krieglstein, J.5
Mattson, M.P.6
-
19
-
-
3142655659
-
Microglia kill amyloid-beta(1-42) damaged neurons by a CD14-dependent process
-
15194867 10.1097/01.wnr.0000132203.76836.16 1:CAS:528: DC%2BD2cXksl2ns70%3D
-
C Bate R Veerhuis P Eikelenboom A Williarns 2004 Microglia kill amyloid-beta(1-42) damaged neurons by a CD14-dependent process Neuroreport 15 1427 1430 15194867 10.1097/01.wnr.0000132203.76836.16 1:CAS:528: DC%2BD2cXksl2ns70%3D
-
(2004)
Neuroreport
, vol.15
, pp. 1427-1430
-
-
Bate, C.1
Veerhuis, R.2
Eikelenboom, P.3
Williarns, A.4
-
21
-
-
0031686954
-
Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: A case-control study in Rochester, Minnesota, 1980 through 1984
-
9787743 10.4065/73.10.951 1:STN:280:DyaK1M%2FgsVSisw%3D%3D
-
CM Beard SC Waring PC O'Brien LT Kurland E Kokmen 1998 Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: a case-control study in Rochester, Minnesota, 1980 through 1984 Mayo Clin Proc 73 951 955 9787743 10.4065/73.10.951 1:STN:280:DyaK1M%2FgsVSisw%3D%3D
-
(1998)
Mayo Clin Proc
, vol.73
, pp. 951-955
-
-
Beard, C.M.1
Waring, S.C.2
O'Brien, P.C.3
Kurland, L.T.4
Kokmen, E.5
-
22
-
-
8744228195
-
Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice
-
15345711 10.1074/jbc.M409544200 1:CAS:528:DC%2BD2cXptFejs74%3D
-
V Beglopoulos X Sun CA Saura CA Lemere RD Kim J Shen 2004 Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice J Biol Chem 279 46907 46914 15345711 10.1074/jbc.M409544200 1:CAS:528:DC%2BD2cXptFejs74%3D
-
(2004)
J Biol Chem
, vol.279
, pp. 46907-46914
-
-
Beglopoulos, V.1
Sun, X.2
Saura, C.A.3
Lemere, C.A.4
Kim, R.D.5
Shen, J.6
-
23
-
-
67349142021
-
Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
-
19319544 10.1007/s00401-009-0522-3 1:CAS:528:DC%2BD1MXmt1ahu7g%3D
-
RD Bell BV Zlokovic 2009 Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease Acta Neuropathol 118 103 113 19319544 10.1007/s00401-009-0522-3 1:CAS:528:DC%2BD1MXmt1ahu7g%3D
-
(2009)
Acta Neuropathol
, vol.118
, pp. 103-113
-
-
Bell, R.D.1
Zlokovic, B.V.2
-
24
-
-
0034802570
-
Immunological aspects of microglia: Relevance to Alzheimer's disease
-
11578773 10.1016/S0197-0186(01)00045-6 1:CAS:528:DC%2BD3MXntVymu78%3D
-
EN Benveniste VT Nguyen GM O'Keefe 2001 Immunological aspects of microglia: relevance to Alzheimer's disease Neurochem Int 39 381 391 11578773 10.1016/S0197-0186(01)00045-6 1:CAS:528:DC%2BD3MXntVymu78%3D
-
(2001)
Neurochem Int
, vol.39
, pp. 381-391
-
-
Benveniste, E.N.1
Nguyen, V.T.2
O'Keefe, G.M.3
-
25
-
-
0033370498
-
Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice
-
10674423 10.1016/S0197-4580(99)00065-2 1:CAS:528:DC%2BD3cXosFSjuw%3D%3D
-
WC Benzing JR Wujek EK Ward D Shaffer KH Ashe SG Younkin KR Brunden 1999 Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice Neurobiol Aging 20 581 589 10674423 10.1016/S0197-4580(99)00065-2 1:CAS:528:DC%2BD3cXosFSjuw%3D%3D
-
(1999)
Neurobiol Aging
, vol.20
, pp. 581-589
-
-
Benzing, W.C.1
Wujek, J.R.2
Ward, E.K.3
Shaffer, D.4
Ashe, K.H.5
Younkin, S.G.6
Brunden, K.R.7
-
26
-
-
0034960228
-
CXCR4-activated astrocyte glutamate release via TNFalpha: Amplification by microglia triggers neurotoxicity
-
11426226 10.1038/89490 1:CAS:528:DC%2BD3MXltVSrsb4%3D
-
P Bezzi M Domercq L Brambilla R Galli D Schols E De Clercq A Vescovi G Bagetta G Kollias J Meldolesi A Volterra 2001 CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity Nat Neurosci 4 702 710 11426226 10.1038/89490 1:CAS:528: DC%2BD3MXltVSrsb4%3D
-
(2001)
Nat Neurosci
, vol.4
, pp. 702-710
-
-
Bezzi, P.1
Domercq, M.2
Brambilla, L.3
Galli, R.4
Schols, D.5
De Clercq, E.6
Vescovi, A.7
Bagetta, G.8
Kollias, G.9
Meldolesi, J.10
Volterra, A.11
-
27
-
-
0035783991
-
Neuron-astrocyte cross-talk during synaptic transmission: Physiological and neuropathological implications
-
Bezzi P, Domercq M, Vesce S, Volterra A (2001b) Neuron-astrocyte cross-talk during synaptic transmission: physiological and neuropathological implications. Prog Brain Res 132:255-265
-
(2001)
Prog Brain Res
, vol.132
, pp. 255-265
-
-
Bezzi, P.1
Domercq, M.2
Vesce, S.3
Volterra, A.4
-
28
-
-
3843129633
-
PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis
-
15293276 10.1002/ana.20179 1:CAS:528:DC%2BD2cXnt1enurg%3D
-
M Bilak L Wu Q Wang N Haughey K Conant C St Hillaire K Andreasson 2004 PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis Ann Neurol 56 240 248 15293276 10.1002/ana.20179 1:CAS:528:DC%2BD2cXnt1enurg%3D
-
(2004)
Ann Neurol
, vol.56
, pp. 240-248
-
-
Bilak, M.1
Wu, L.2
Wang, Q.3
Haughey, N.4
Conant, K.5
St Hillaire, C.6
Andreasson, K.7
-
29
-
-
0032621790
-
TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs
-
9872930 1:CAS:528:DyaK1MXlt1ygug%3D%3D
-
I Blasko F Marx E Steiner T Hartmann B Grubeck-Loebenstein 1999 TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs FASEB J 13 63 68 9872930 1:CAS:528: DyaK1MXlt1ygug%3D%3D
-
(1999)
FASEB J
, vol.13
, pp. 63-68
-
-
Blasko, I.1
Marx, F.2
Steiner, E.3
Hartmann, T.4
Grubeck-Loebenstein, B.5
-
30
-
-
0034523456
-
Costimulatory effects of interferon-gamma and interleukin-1beta or tumor necrosis factor alpha on the synthesis of Abeta1-40 and Abeta1-42 by human astrocytes
-
11114266 10.1006/nbdi.2000.0321 1:CAS:528:DC%2BD3cXoslSms7k%3D
-
I Blasko R Veerhuis M Stampfer-Kountchev M Saurwein-Teissl P Eikelenboom B Grubeck-Loebenstein 2000 Costimulatory effects of interferon-gamma and interleukin-1beta or tumor necrosis factor alpha on the synthesis of Abeta1-40 and Abeta1-42 by human astrocytes Neurobiol Dis 7 682 689 11114266 10.1006/nbdi.2000.0321 1:CAS:528:DC%2BD3cXoslSms7k%3D
-
(2000)
Neurobiol Dis
, vol.7
, pp. 682-689
-
-
Blasko, I.1
Veerhuis, R.2
Stampfer-Kountchev, M.3
Saurwein-Teissl, M.4
Eikelenboom, P.5
Grubeck-Loebenstein, B.6
-
31
-
-
1842728419
-
Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1)
-
15057522 10.1007/s00702-003-0095-6 1:CAS:528:DC%2BD2cXis1Ggs7Y%3D
-
I Blasko R Beer M Bigl J Apelt G Franz D Rudzki G Ransmayr A Kampfl R Schliebs 2004 Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1) J Neural Transm 111 523 536 15057522 10.1007/s00702-003-0095-6 1:CAS:528:DC%2BD2cXis1Ggs7Y%3D
-
(2004)
J Neural Transm
, vol.111
, pp. 523-536
-
-
Blasko, I.1
Beer, R.2
Bigl, M.3
Apelt, J.4
Franz, G.5
Rudzki, D.6
Ransmayr, G.7
Kampfl, A.8
Schliebs, R.9
-
32
-
-
0026702955
-
Microglial-produced nitric-oxide and reactive nitrogen-oxides mediate neuronal cell-death
-
1381982 10.1016/0006-8993(92)91004-X 1:CAS:528:DyaK38XlvV2ntro%3D
-
KM Boje PK Arora 1992 Microglial-produced nitric-oxide and reactive nitrogen-oxides mediate neuronal cell-death Brain Res 587 250 256 1381982 10.1016/0006-8993(92)91004-X 1:CAS:528:DyaK38XlvV2ntro%3D
-
(1992)
Brain Res
, vol.587
, pp. 250-256
-
-
Boje, K.M.1
Arora, P.K.2
-
33
-
-
42949175211
-
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
-
18417708 10.1523/JNEUROSCI.4814-07.2008 1:CAS:528:DC%2BD1cXltVOnu7Y%3D
-
T Bolmont F Haiss D Eicke R Radde CA Mathis WE Klunk S Kohsaka M Jucker ME Calhoun 2008 Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance J Neurosci 28 4283 4292 18417708 10.1523/JNEUROSCI.4814- 07.2008 1:CAS:528:DC%2BD1cXltVOnu7Y%3D
-
(2008)
J Neurosci
, vol.28
, pp. 4283-4292
-
-
Bolmont, T.1
Haiss, F.2
Eicke, D.3
Radde, R.4
Mathis, C.A.5
Klunk, W.E.6
Kohsaka, S.7
Jucker, M.8
Calhoun, M.E.9
-
34
-
-
0034713266
-
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
-
10839541 10.1038/35013070 1:CAS:528:DC%2BD3cXjslyltbY%3D
-
LV Borovikova S Ivanova M Zhang H Yang GI Botchkina LR Watkins H Wang N Abumrad JW Eaton KJ Tracey 2000 Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Nature 405 458 462 10839541 10.1038/35013070 1:CAS:528:DC%2BD3cXjslyltbY%3D
-
(2000)
Nature
, vol.405
, pp. 458-462
-
-
Borovikova, L.V.1
Ivanova, S.2
Zhang, M.3
Yang, H.4
Botchkina, G.I.5
Watkins, L.R.6
Wang, H.7
Abumrad, N.8
Eaton, J.W.9
Tracey, K.J.10
-
35
-
-
0031470830
-
Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia
-
9407552 1:CAS:528:DyaK1cXhvFY%3D
-
GI Botchkina ME Meistrell III IL Botchkina KJ Tracey 1997 Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia Mol Med 3 765 781 9407552 1:CAS:528:DyaK1cXhvFY%3D
-
(1997)
Mol Med
, vol.3
, pp. 765-781
-
-
Botchkina, G.I.1
Meistrell III, M.E.2
Botchkina, I.L.3
Tracey, K.J.4
-
36
-
-
0032462810
-
C1q knock-out mice for the study of complement deficiency in autoimmune disease
-
10072632 10.1159/000019076 1:CAS:528:DyaK1MXit1KrtLc%3D
-
M Botto 1998 C1q knock-out mice for the study of complement deficiency in autoimmune disease Exp Clin Immunogenet 15 231 234 10072632 10.1159/000019076 1:CAS:528:DyaK1MXit1KrtLc%3D
-
(1998)
Exp Clin Immunogenet
, vol.15
, pp. 231-234
-
-
Botto, M.1
-
37
-
-
0031596284
-
Evolution of neuronal changes in the course of Alzheimer's disease
-
9700651 1:STN:280:DyaK1czms1Sjug%3D%3D
-
H Braak E Braak 1998 Evolution of neuronal changes in the course of Alzheimer's disease J Neural Transm Suppl 53 127-40 127 140 9700651 1:STN:280:DyaK1czms1Sjug%3D%3D
-
(1998)
J Neural Transm Suppl
, vol.53
, pp. 12740-127140
-
-
Braak, H.1
Braak, E.2
-
38
-
-
3242723955
-
Cognitive function in young and adult IL (interleukin)-6 deficient mice
-
15265638 10.1016/j.bbr.2003.12.018 1:CAS:528:DC%2BD2cXlsl2jtrY%3D
-
D Braida P Sacerdote AE Panerai M Bianchi AM Aloisi S Iosue M Sala 2004 Cognitive function in young and adult IL (interleukin)-6 deficient mice Behav Brain Res 153 423 429 15265638 10.1016/j.bbr.2003.12.018 1:CAS:528: DC%2BD2cXlsl2jtrY%3D
-
(2004)
Behav Brain Res
, vol.153
, pp. 423-429
-
-
Braida, D.1
Sacerdote, P.2
Panerai, A.E.3
Bianchi, M.4
Aloisi, A.M.5
Iosue, S.6
Sala, M.7
-
39
-
-
0027483753
-
Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivity in the murine central nervous system
-
8288770 10.1002/cne.903370403 1:CAS:528:DyaK2cXhs1Whurk%3D
-
CD Breder M Tsujimoto Y Terano DW Scott CB Saper 1993 Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivity in the murine central nervous system J Comp Neurol 337 543 567 8288770 10.1002/cne.903370403 1:CAS:528:DyaK2cXhs1Whurk%3D
-
(1993)
J Comp Neurol
, vol.337
, pp. 543-567
-
-
Breder, C.D.1
Tsujimoto, M.2
Terano, Y.3
Scott, D.W.4
Saper, C.B.5
-
40
-
-
0025191219
-
Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme
-
1689048 10.1073/pnas.87.2.682 1:CAS:528:DyaK3cXhtlGjt70%3D
-
DS Bredt SH Snyder 1990 Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme Proc Natl Acad Sci USA 87 682 685 1689048 10.1073/pnas.87.2.682 1:CAS:528:DyaK3cXhtlGjt70%3D
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 682-685
-
-
Bredt, D.S.1
Snyder, S.H.2
-
41
-
-
0036326074
-
Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
-
12153485 10.1046/j.1471-4159.2002.00990.x 1:CAS:528:DC%2BD38Xmt1ejsLY%3D
-
T Breidert J Callebert MT Heneka G Landreth JM Launay EC Hirsch 2002 Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease J Neurochem 82 615 624 12153485 10.1046/j.1471-4159.2002.00990.x 1:CAS:528:DC%2BD38Xmt1ejsLY%3D
-
(2002)
J Neurochem
, vol.82
, pp. 615-624
-
-
Breidert, T.1
Callebert, J.2
Heneka, M.T.3
Landreth, G.4
Launay, J.M.5
Hirsch, E.C.6
-
42
-
-
0030250376
-
Inflammatory processes and antiinflammatory drugs in Alzheimer's disease: A current appraisal
-
8892353 10.1016/0197-4580(96)00109-1 1:STN:280:DyaK2s%2FkslCgsQ%3D%3D
-
JC Breitner 1996 Inflammatory processes and antiinflammatory drugs in Alzheimer's disease: a current appraisal Neurobiol Aging 17 789 794 8892353 10.1016/0197-4580(96)00109-1 1:STN:280:DyaK2s%2FkslCgsQ%3D%3D
-
(1996)
Neurobiol Aging
, vol.17
, pp. 789-794
-
-
Breitner, J.C.1
-
43
-
-
0035936009
-
Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease?
-
11794225 10.1056/NEJM200111223452110 1:STN:280:DC%2BD38%2FmsFGkuw%3D%3D
-
JC Breitner PP Zandi 2001 Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease? N Engl J Med 345 1567 1568 11794225 10.1056/NEJM200111223452110 1:STN:280:DC%2BD38%2FmsFGkuw%3D%3D
-
(2001)
N Engl J Med
, vol.345
, pp. 1567-1568
-
-
Breitner, J.C.1
Zandi, P.P.2
-
44
-
-
0029160270
-
Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs
-
8544901 10.1016/0197-4580(95)00049-K 1:STN:280:DyaK287ltleqsQ%3D%3D
-
JC Breitner KA Welsh MJ Helms PC Gaskell BA Gau AD Roses MA Pericak-Vance AM Saunders 1995 Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs Neurobiol Aging 16 523 530 8544901 10.1016/0197-4580(95)00049-K 1:STN:280:DyaK287ltleqsQ%3D%3D
-
(1995)
Neurobiol Aging
, vol.16
, pp. 523-530
-
-
Breitner, J.C.1
Welsh, K.A.2
Helms, M.J.3
Gaskell, P.C.4
Gau, B.A.5
Roses, A.D.6
Pericak-Vance, M.A.7
Saunders, A.M.8
-
45
-
-
0041784698
-
Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria
-
12845153 10.1385/MN:27:3:325 1:CAS:528:DC%2BD3sXmtVyktrY%3D
-
GC Brown A Bal-Price 2003 Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria Mol Neurobiol 27 325 355 12845153 10.1385/MN:27:3:325 1:CAS:528:DC%2BD3sXmtVyktrY%3D
-
(2003)
Mol Neurobiol
, vol.27
, pp. 325-355
-
-
Brown, G.C.1
Bal-Price, A.2
-
46
-
-
20444364844
-
Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective
-
15890528 10.1016/j.mcn.2005.03.005 1:CAS:528:DC%2BD2MXltFejt7c%3D
-
O Butovsky AE Talpalar K Ben Yaakov M Schwartz 2005 Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective Mol Cell Neurosci 29 381 393 15890528 10.1016/j.mcn.2005.03.005 1:CAS:528:DC%2BD2MXltFejt7c%3D
-
(2005)
Mol Cell Neurosci
, vol.29
, pp. 381-393
-
-
Butovsky, O.1
Talpalar, A.E.2
Ben Yaakov, K.3
Schwartz, M.4
-
47
-
-
0041302369
-
Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia
-
12859668 10.1046/j.1471-4159.2003.01812.x 1:CAS:528:DC%2BD3sXlvF2ntb8%3D
-
E Candelario-Jalil A Gonzalez-Falcon M Garcia-Cabrera D Alvarez S Al Dalain G Martinez OS Leon JE Springer 2003 Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia J Neurochem 86 545 555 12859668 10.1046/j.1471-4159.2003.01812.x 1:CAS:528: DC%2BD3sXlvF2ntb8%3D
-
(2003)
J Neurochem
, vol.86
, pp. 545-555
-
-
Candelario-Jalil, E.1
Gonzalez-Falcon, A.2
Garcia-Cabrera, M.3
Alvarez, D.4
Al Dalain, S.5
Martinez, G.6
Leon, O.S.7
Springer, J.E.8
-
48
-
-
33745573660
-
Control of microglial neurotoxicity by the fractalkine receptor
-
16732273 10.1038/nn1715 1:CAS:528:DC%2BD28XmtFCmsbw%3D
-
AE Cardona EP Pioro ME Sasse V Kostenko SM Cardona IM Dijkstra DR Huang G Kidd S Dombrowski R Dutta JC Lee DN Cook S Jung SA Lira DR Littman RM Ransohoff 2006 Control of microglial neurotoxicity by the fractalkine receptor Nat Neurosci 9 917 924 16732273 10.1038/nn1715 1:CAS:528:DC%2BD28XmtFCmsbw%3D
-
(2006)
Nat Neurosci
, vol.9
, pp. 917-924
-
-
Cardona, A.E.1
Pioro, E.P.2
Sasse, M.E.3
Kostenko, V.4
Cardona, S.M.5
Dijkstra, I.M.6
Huang, D.R.7
Kidd, G.8
Dombrowski, S.9
Dutta, R.10
Lee, J.C.11
Cook, D.N.12
Jung, S.13
Lira, S.A.14
Littman, D.R.15
Ransohoff, R.M.16
-
49
-
-
0024323353
-
Interleukin-6. The major regulator of acute-phase protein synthesis in man and rat
-
2472097 10.1111/j.1749-6632.1989.tb24001.x 1:CAS:528:DyaL1MXltlWqtLw%3D (discussion 100-1)
-
JV Castell T Andus D Kunz PC Heinrich 1989 Interleukin-6. The major regulator of acute-phase protein synthesis in man and rat Ann N Y Acad Sci 557 87 99 2472097 10.1111/j.1749-6632.1989.tb24001.x 1:CAS:528:DyaL1MXltlWqtLw%3D (discussion 100-1)
-
(1989)
Ann N y Acad Sci
, vol.557
, pp. 87-99
-
-
Castell, J.V.1
Andus, T.2
Kunz, D.3
Heinrich, P.C.4
-
50
-
-
76149092520
-
Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: Evidence against inflammation as a driving force for amyloid deposition
-
19825975 10.1096/fj.09-141754 1:CAS:528:DC%2BC3cXhs1Ggsr4%3D
-
P Chakrabarty K Jansen-West A Beccard C Ceballos-Diaz Y Levites C Verbeeck AC Zubair D Dickson TE Golde P Das 2010 Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition FASEB J 24 548 559 19825975 10.1096/fj.09-141754 1:CAS:528:DC%2BC3cXhs1Ggsr4%3D
-
(2010)
FASEB J
, vol.24
, pp. 548-559
-
-
Chakrabarty, P.1
Jansen-West, K.2
Beccard, A.3
Ceballos-Diaz, C.4
Levites, Y.5
Verbeeck, C.6
Zubair, A.C.7
Dickson, D.8
Golde, T.E.9
Das, P.10
-
51
-
-
0030108525
-
Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
-
8833198 10.1002/(SICI)1098-1136(199603)16:3 <276::AID-GLIA10>3.0. CO;2-X 1:STN:280:DyaK28vjtVSnug%3D%3D
-
CC Chao S Hu WS Sheng D Bu MI Bukrinsky PK Peterson 1996 Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism Glia 16 276 284 8833198 10.1002/(SICI)1098-1136(199603)16:3<276::AID- GLIA10>3.0.CO;2-X 1:STN:280:DyaK28vjtVSnug%3D%3D
-
(1996)
Glia
, vol.16
, pp. 276-284
-
-
Chao, C.C.1
Hu, S.2
Sheng, W.S.3
Bu, D.4
Bukrinsky, M.I.5
Peterson, P.K.6
-
52
-
-
32144454172
-
Mechanisms of disease - The many roles of chemokines and chemokine receptors in inflammation
-
16467548 10.1056/NEJMra052723 1:CAS:528:DC%2BD28XhtlKisro%3D
-
IF Charo RM Ransohoff 2006 Mechanisms of disease-the many roles of chemokines and chemokine receptors in inflammation N Engl J Med 354 610 621 16467548 10.1056/NEJMra052723 1:CAS:528:DC%2BD28XhtlKisro%3D
-
(2006)
N Engl J Med
, vol.354
, pp. 610-621
-
-
Charo, I.F.1
Ransohoff, R.M.2
-
53
-
-
0035132330
-
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
11135615 10.1038/83336 1:CAS:528:DC%2BD3MXmvV2nuw%3D%3D
-
A Chawla Y Barak L Nagy D Liao P Tontonoz RM Evans 2001 PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation Nat Med 7 48 52 11135615 10.1038/83336 1:CAS:528:DC%2BD3MXmvV2nuw%3D%3D
-
(2001)
Nat Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
54
-
-
33645650780
-
Activation of toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide
-
16339765 10.1074/jbc.M508125200 1:CAS:528:DC%2BD28XhtFSmt7o%3D
-
KQ Chen P Iribarren JY Hu JH Chen WH Gong EH Cho S Lockett NM Dunlop JM Wang 2006 Activation of toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide J Biol Chem 281 3651 3659 16339765 10.1074/jbc.M508125200 1:CAS:528:DC%2BD28XhtFSmt7o%3D
-
(2006)
J Biol Chem
, vol.281
, pp. 3651-3659
-
-
Chen, K.Q.1
Iribarren, P.2
Hu, J.Y.3
Chen, J.H.4
Gong, W.H.5
Cho, E.H.6
Lockett, S.7
Dunlop, N.M.8
Wang, J.M.9
-
55
-
-
0030700349
-
Effect of a carboxy-terminal fragment of the Alzheimer's amyloid precursor protein on expression of proinflammatory cytokines in rat glial cells
-
9408055 10.1016/S0024-3205(97)00936-3 1:CAS:528:DyaK2sXntl2it7s%3D
-
Y Chong 1997 Effect of a carboxy-terminal fragment of the Alzheimer's amyloid precursor protein on expression of proinflammatory cytokines in rat glial cells Life Sci 61 2323 2333 9408055 10.1016/S0024-3205(97)00936-3 1:CAS:528:DyaK2sXntl2it7s%3D
-
(1997)
Life Sci
, vol.61
, pp. 2323-2333
-
-
Chong, Y.1
-
56
-
-
33847649449
-
Chromogranin A triggers the expression of neurotoxic phenotype in microglia and induces apoptosis in neuronal/microglial cocultures
-
J Ciesielski-Treska G Ulrich D Aunis MF Bader 1998 Chromogranin A triggers the expression of neurotoxic phenotype in microglia and induces apoptosis in neuronal/microglial cocultures Eur J Neurosci 10 164
-
(1998)
Eur J Neurosci
, vol.10
, pp. 164
-
-
Ciesielski-Treska, J.1
Ulrich, G.2
Aunis, D.3
Bader, M.F.4
-
57
-
-
0032486395
-
Chromogranin A induces a neurotoxic phenotype in brain microglial cells
-
9603942 10.1074/jbc.273.23.14339 1:CAS:528:DyaK1cXjs1Oru74%3D
-
J Ciesielski-Treska G Ulrich L Taupenot S Chasserot-Golaz A Corti D Aunis MF Bader 1998 Chromogranin A induces a neurotoxic phenotype in brain microglial cells J Biol Chem 273 14339 14346 9603942 10.1074/jbc.273.23.14339 1:CAS:528:DyaK1cXjs1Oru74%3D
-
(1998)
J Biol Chem
, vol.273
, pp. 14339-14346
-
-
Ciesielski-Treska, J.1
Ulrich, G.2
Taupenot, L.3
Chasserot-Golaz, S.4
Corti, A.5
Aunis, D.6
Bader, M.F.7
-
58
-
-
0034651101
-
Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
-
10632585 1:CAS:528:DC%2BD3cXhtF2hsLk%3D
-
CK Combs DE Johnson JC Karlo SB Cannady GE Landreth 2000 Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists J Neurosci 20 558 567 10632585 1:CAS:528:DC%2BD3cXhtF2hsLk%3D
-
(2000)
J Neurosci
, vol.20
, pp. 558-567
-
-
Combs, C.K.1
Johnson, D.E.2
Karlo, J.C.3
Cannady, S.B.4
Landreth, G.E.5
-
59
-
-
0035866060
-
Beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
-
11160388 1:CAS:528:DC%2BD3MXhtFers7c%3D
-
CK Combs JC Karlo SC Kao GE Landreth 2001 beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis J Neurosci 21 1179 1188 11160388 1:CAS:528:DC%2BD3MXhtFers7c%3D
-
(2001)
J Neurosci
, vol.21
, pp. 1179-1188
-
-
Combs, C.K.1
Karlo, J.C.2
Kao, S.C.3
Landreth, G.E.4
-
60
-
-
0027563713
-
Inducible nitric oxide synthase activity of cloned murine microglial cells
-
7681038 10.1002/glia.440070309 1:STN:280:DyaK3s3gt1Ojsg%3D%3D
-
SB Corradin J Mauel SD Donini E Quattrocchi P Ricciardi-Castagnoli 1993 Inducible nitric oxide synthase activity of cloned murine microglial cells Glia 7 255 262 7681038 10.1002/glia.440070309 1:STN:280:DyaK3s3gt1Ojsg%3D%3D
-
(1993)
Glia
, vol.7
, pp. 255-262
-
-
Corradin, S.B.1
Mauel, J.2
Donini, S.D.3
Quattrocchi, E.4
Ricciardi-Castagnoli, P.5
-
61
-
-
2942618440
-
Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma
-
15187132 1:CAS:528:DC%2BD2cXks1ahu7s%3D
-
R Cunard Y Eto JT Muljadi CK Glass CJ Kelly M Ricote 2004 Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma J Immunol 172 7530 7536 15187132 1:CAS:528:DC%2BD2cXks1ahu7s%3D
-
(2004)
J Immunol
, vol.172
, pp. 7530-7536
-
-
Cunard, R.1
Eto, Y.2
Muljadi, J.T.3
Glass, C.K.4
Kelly, C.J.5
Ricote, M.6
-
62
-
-
2542431100
-
The microglial phagocytic role with specific plaque types in the Alzheimer disease brain
-
15172747 10.1016/j.neurobiolaging.2003.12.026 1:CAS:528: DC%2BD2cXksVGgtLs%3D
-
MR D'Andrea GM Cole MD Ard 2004 The microglial phagocytic role with specific plaque types in the Alzheimer disease brain Neurobiol Aging 25 675 683 15172747 10.1016/j.neurobiolaging.2003.12.026 1:CAS:528:DC%2BD2cXksVGgtLs%3D
-
(2004)
Neurobiol Aging
, vol.25
, pp. 675-683
-
-
D'Andrea, M.R.1
Cole, G.M.2
Ard, M.D.3
-
63
-
-
0042285737
-
What can rodent models tell us about cognitive decline in Alzheimer's disease?
-
12845151 10.1385/MN:27:3:249 1:CAS:528:DC%2BD3sXmtVyktrg%3D
-
S Davis S Laroche 2003 What can rodent models tell us about cognitive decline in Alzheimer's disease? Mol Neurobiol 27 249 276 12845151 10.1385/MN:27:3:249 1:CAS:528:DC%2BD3sXmtVyktrg%3D
-
(2003)
Mol Neurobiol
, vol.27
, pp. 249-276
-
-
Davis, S.1
Laroche, S.2
-
64
-
-
0028089896
-
Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures
-
7532825 10.1016/0028-3908(94)90045-0 1:CAS:528:DyaK2cXmvFOqsbo%3D
-
VL Dawson HP Brahmbhatt JA Mong TM Dawson 1994 Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures Neuropharmacology 33 1425 1430 7532825 10.1016/0028-3908(94)90045-0 1:CAS:528:DyaK2cXmvFOqsbo%3D
-
(1994)
Neuropharmacology
, vol.33
, pp. 1425-1430
-
-
Dawson, V.L.1
Brahmbhatt, H.P.2
Mong, J.A.3
Dawson, T.M.4
-
65
-
-
0036779687
-
Emerging roles of PPARs in inflammation and immunity
-
12360213 10.1038/nri912 1:CAS:528:DC%2BD38XnsVGqsbY%3D
-
RA Daynes DC Jones 2002 Emerging roles of PPARs in inflammation and immunity Nat Rev Immunol 2 748 759 12360213 10.1038/nri912 1:CAS:528: DC%2BD38XnsVGqsbY%3D
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 748-759
-
-
Daynes, R.A.1
Jones, D.C.2
-
66
-
-
0037089102
-
APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy
-
11948811 10.1002/glia.10052
-
LA DeGiorgio Y Shimizu HS Chun BP Cho S Sugama TH Joh BT Volpe 2002 APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy Glia 38 174 178 11948811 10.1002/glia.10052
-
(2002)
Glia
, vol.38
, pp. 174-178
-
-
Degiorgio, L.A.1
Shimizu, Y.2
Chun, H.S.3
Cho, B.P.4
Sugama, S.5
Joh, T.H.6
Volpe, B.T.7
-
67
-
-
0347087323
-
Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with i kappa B alpha induction and block of NF kappa B and iNOS activation
-
14690537 10.1046/j.1471-4159.2003.02210.x 1:CAS:528: DC%2BD2cXntlWjug%3D%3D
-
T Dehmer MT Heneka M Sastre J Dichgans JB Schulz 2004 Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation J Neurochem 88 494 501 14690537 10.1046/j.1471-4159.2003.02210.x 1:CAS:528:DC%2BD2cXntlWjug%3D%3D
-
(2004)
J Neurochem
, vol.88
, pp. 494-501
-
-
Dehmer, T.1
Heneka, M.T.2
Sastre, M.3
Dichgans, J.4
Schulz, J.B.5
-
68
-
-
0033979993
-
Inflammation and stroke: Putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia
-
10668900 10.1111/j.1750-3639.2000.tb00247.x 1:CAS:528: DC%2BD3cXpslSrsg%3D%3D
-
G del Zoppo I Ginis JM Hallenbeck C Iadecola X Wang GZ Feuerstein 2000 Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia Brain Pathol 10 95 112 10668900 10.1111/j.1750-3639.2000.tb00247.x 1:CAS:528:DC%2BD3cXpslSrsg%3D%3D
-
(2000)
Brain Pathol
, vol.10
, pp. 95-112
-
-
Del Zoppo, G.1
Ginis, I.2
Hallenbeck, J.M.3
Iadecola, C.4
Wang, X.5
Feuerstein, G.Z.6
-
69
-
-
0027221653
-
Nitric oxide synthase induction in glial cells: Effect on neuronal survival
-
7684804 10.1016/0024-3205(93)90009-R 1:CAS:528:DyaK3sXkt1Giurc%3D
-
C Demerle-Pallardy MO Lonchampt PE Chabrier P Braquet 1993 Nitric oxide synthase induction in glial cells: effect on neuronal survival Life Sci 52 1883 1890 7684804 10.1016/0024-3205(93)90009-R 1:CAS:528:DyaK3sXkt1Giurc%3D
-
(1993)
Life Sci
, vol.52
, pp. 1883-1890
-
-
Demerle-Pallardy, C.1
Lonchampt, M.O.2
Chabrier, P.E.3
Braquet, P.4
-
70
-
-
18144453796
-
Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease
-
9500964 10.1006/exnr.1997.6738 1:STN:280:DyaK1c7mt1Clug%3D%3D
-
DA Dewitt G Perry M Cohen C Doller J Silver 1998 Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease Exp Neurol 149 329 340 9500964 10.1006/exnr.1997.6738 1:STN:280:DyaK1c7mt1Clug%3D%3D
-
(1998)
Exp Neurol
, vol.149
, pp. 329-340
-
-
Dewitt, D.A.1
Perry, G.2
Cohen, M.3
Doller, C.4
Silver, J.5
-
71
-
-
1242317642
-
Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis
-
14975592 10.1016/j.jneuroim.2003.11.010 1:CAS:528:DC%2BD2cXht1yksb8%3D
-
A Diab RZ Hussain AE Lovett-Racke JA Chavis PD Drew MK Racke 2004 Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis J Neuroimmunol 148 116 126 14975592 10.1016/j.jneuroim.2003. 11.010 1:CAS:528:DC%2BD2cXht1yksb8%3D
-
(2004)
J Neuroimmunol
, vol.148
, pp. 116-126
-
-
Diab, A.1
Hussain, R.Z.2
Lovett-Racke, A.E.3
Chavis, J.A.4
Drew, P.D.5
Racke, M.K.6
-
72
-
-
0027354484
-
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
-
8423065 10.1002/glia.440070113 1:STN:280:DyaK3s7jvVOntQ%3D%3D
-
DW Dickson SC Lee LA Mattiace SH Yen C Brosnan 1993 Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease Glia 7 75 83 8423065 10.1002/glia.440070113 1:STN:280:DyaK3s7jvVOntQ%3D%3D
-
(1993)
Glia
, vol.7
, pp. 75-83
-
-
Dickson, D.W.1
Lee, S.C.2
Mattiace, L.A.3
Yen, S.H.4
Brosnan, C.5
-
73
-
-
73649137143
-
Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid beta neurotoxicity in in vitro and in vivo models of Alzheimer's disease
-
19834064 10.2353/ajpath.2009.090418 1:CAS:528:DC%2BC3cXhslSjtbg%3D
-
Y Doi T Mizuno Y Maki S Jin H Mizoguchi M Ikeyama M Doi M Michikawa H Takeuchi A Suzumura 2009 Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid beta neurotoxicity in in vitro and in vivo models of Alzheimer's disease Am J Pathol 175 2121 2132 19834064 10.2353/ajpath.2009.090418 1:CAS:528:DC%2BC3cXhslSjtbg%3D
-
(2009)
Am J Pathol
, vol.175
, pp. 2121-2132
-
-
Doi, Y.1
Mizuno, T.2
Maki, Y.3
Jin, S.4
Mizoguchi, H.5
Ikeyama, M.6
Doi, M.7
Michikawa, M.8
Takeuchi, H.9
Suzumura, A.10
-
74
-
-
0000920292
-
Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
-
10.1073/pnas.94.21.11657
-
YS Du H Zhu J Fu SF Yan A Roher WW Tourtellotte T Rajavashisth X Chen GC Godman D Stern AM Schmidt 1997 Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease Proc Natl Acad Sci USA 94 5296 5301 10.1073/pnas.94.21.11657
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5296-5301
-
-
Du, Y.S.1
Zhu, H.2
Fu, J.3
Yan, S.F.4
Roher, A.5
Tourtellotte, W.W.6
Rajavashisth, T.7
Chen, X.8
Godman, G.C.9
Stern, D.10
Schmidt, A.M.11
-
76
-
-
1542283611
-
Neuroinflammatory perspectives on the two faces of Alzheimer's disease
-
14991455 10.1007/s00702-003-0055-1 1:CAS:528:DC%2BD2cXhsFequ7k%3D
-
P Eikelenboom WA van Gool 2004 Neuroinflammatory perspectives on the two faces of Alzheimer's disease J Neural Transm 111 281 294 14991455 10.1007/s00702-003-0055-1 1:CAS:528:DC%2BD2cXhsFequ7k%3D
-
(2004)
J Neural Transm
, vol.111
, pp. 281-294
-
-
Eikelenboom, P.1
Van Gool, W.A.2
-
77
-
-
0030250852
-
The role of complement and activated microglia in the pathogenesis of Alzheimer's disease
-
8892339 10.1016/0197-4580(96)00108-X 1:STN:280:DyaK2s%2FkslCiuw%3D%3D
-
P Eikelenboom R Veerhuis 1996 The role of complement and activated microglia in the pathogenesis of Alzheimer's disease Neurobiol Aging 17 673 680 8892339 10.1016/0197-4580(96)00108-X 1:STN:280:DyaK2s%2FkslCiuw%3D%3D
-
(1996)
Neurobiol Aging
, vol.17
, pp. 673-680
-
-
Eikelenboom, P.1
Veerhuis, R.2
-
78
-
-
0024543574
-
Complement activation in amyloid plaques in Alzheimers dementia
-
2565620 10.1007/BF02890024 1:STN:280:DyaL1M3isVWmsg%3D%3D
-
P Eikelenboom CE Hack JM Rozemuller FC Stam 1989 Complement activation in amyloid plaques in Alzheimers dementia Virchows Arch B Cell Pathol Incl Mol Pathol 56 259 262 2565620 10.1007/BF02890024 1:STN:280:DyaL1M3isVWmsg%3D%3D
-
(1989)
Virchows Arch B Cell Pathol Incl Mol Pathol
, vol.56
, pp. 259-262
-
-
Eikelenboom, P.1
Hack, C.E.2
Rozemuller, J.M.3
Stam, F.C.4
-
79
-
-
0028099622
-
Inflammatory mechanisms in Alzheimer's disease
-
7886816 10.1016/0165-6147(94)90057-4 1:CAS:528:DyaK2MXivFKku7o%3D
-
P Eikelenboom SS Zhan WA van Gool D Allsop 1994 Inflammatory mechanisms in Alzheimer's disease Trends Pharmacol Sci 15 447 450 7886816 10.1016/0165-6147(94)90057-4 1:CAS:528:DyaK2MXivFKku7o%3D
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 447-450
-
-
Eikelenboom, P.1
Zhan, S.S.2
Van Gool, W.A.3
Allsop, D.4
-
80
-
-
85047691727
-
NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo
-
12897211 1:CAS:528:DC%2BD3sXmtFemtrY%3D
-
JL Eriksen SA Sagi TE Smith S Weggen P Das DC McLendon VV Ozols KW Jessing KH Zavitz EH Koo TE Golde 2003 NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo J Clin Invest 112 440 449 12897211 1:CAS:528:DC%2BD3sXmtFemtrY%3D
-
(2003)
J Clin Invest
, vol.112
, pp. 440-449
-
-
Eriksen, J.L.1
Sagi, S.A.2
Smith, T.E.3
Weggen, S.4
Das, P.5
McLendon, D.C.6
Ozols, V.V.7
Jessing, K.W.8
Zavitz, K.H.9
Koo, E.H.10
Golde, T.E.11
-
81
-
-
0038375640
-
Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies
-
12869452 10.1136/bmj.327.7407.128 1:CAS:528:DC%2BD3sXmsl2nu7o%3D
-
M Etminan S Gill A Samii 2003 Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies BMJ 327 128 12869452 10.1136/bmj.327.7407.128 1:CAS:528:DC%2BD3sXmsl2nu7o%3D
-
(2003)
BMJ
, vol.327
, pp. 128
-
-
Etminan, M.1
Gill, S.2
Samii, A.3
-
82
-
-
1342332161
-
The LPS receptor (CD14) links innate immunity with Alzheimer's disease
-
14597556 1:CAS:528:DC%2BD2cXlvFymsg%3D%3D
-
K Fassbender S Walter S Kühl R Landmann K Ishii T Bertsch AK Stalder F Muehlhauser Y Liu AJ Ulmer S Rivest A Lentschat E Gulbins M Jucker M Staufenbiel K Brechtel J Walter G Multhaup B Penke Y Adachi T Hartmann K Beyreuther 2004 The LPS receptor (CD14) links innate immunity with Alzheimer's disease FASEB J 18 203 205 14597556 1:CAS:528:DC%2BD2cXlvFymsg%3D%3D
-
(2004)
FASEB J
, vol.18
, pp. 203-205
-
-
Fassbender, K.1
Walter, S.2
Kühl, S.3
Landmann, R.4
Ishii, K.5
Bertsch, T.6
Stalder, A.K.7
Muehlhauser, F.8
Liu, Y.9
Ulmer, A.J.10
Rivest, S.11
Lentschat, A.12
Gulbins, E.13
Jucker, M.14
Staufenbiel, M.15
Brechtel, K.16
Walter, J.17
Multhaup, G.18
Penke, B.19
Adachi, Y.20
Hartmann, T.21
Beyreuther, K.22
more..
-
83
-
-
0036260784
-
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis
-
12112074 10.1002/ana.10206 1:CAS:528:DC%2BD3sXhsFygsb0%3D
-
DL Feinstein E Galea V Gavrilyuk CF Brosnan CC Whitacre L Dumitrescu-Ozimek GE Landreth HA Pershadsingh G Weinberg MT Heneka 2002 Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis Ann Neurol 51 694 702 12112074 10.1002/ana.10206 1:CAS:528:DC%2BD3sXhsFygsb0%3D
-
(2002)
Ann Neurol
, vol.51
, pp. 694-702
-
-
Feinstein, D.L.1
Galea, E.2
Gavrilyuk, V.3
Brosnan, C.F.4
Whitacre, C.C.5
Dumitrescu-Ozimek, L.6
Landreth, G.E.7
Pershadsingh, H.A.8
Weinberg, G.9
Heneka, M.T.10
-
84
-
-
0035993240
-
Noradrenergic regulation of inflammatory gene expression in brain
-
12176079 10.1016/S0197-0186(02)00049-9 1:CAS:528:DC%2BD38Xmtlemt70%3D
-
DL Feinstein MT Heneka V Gavrilyuk RC Dello G Weinberg E Galea 2002 Noradrenergic regulation of inflammatory gene expression in brain Neurochem Int 41 357 365 12176079 10.1016/S0197-0186(02)00049-9 1:CAS:528:DC%2BD38Xmtlemt70%3D
-
(2002)
Neurochem Int
, vol.41
, pp. 357-365
-
-
Feinstein, D.L.1
Heneka, M.T.2
Gavrilyuk, V.3
Dello, R.C.4
Weinberg, G.5
Galea, E.6
-
85
-
-
20444497357
-
Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key?
-
15925327 10.1016/j.bcp.2005.03.033 1:CAS:528:DC%2BD2MXlt1Skt74%3D
-
DL Feinstein A Spagnolo C Akar G Weinberg P Murphy V Gavrilyuk CD Russo 2005 Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key? Biochem Pharmacol 70 177 188 15925327 10.1016/j.bcp.2005.03.033 1:CAS:528:DC%2BD2MXlt1Skt74%3D
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 177-188
-
-
Feinstein, D.L.1
Spagnolo, A.2
Akar, C.3
Weinberg, G.4
Murphy, P.5
Gavrilyuk, V.6
Russo, C.D.7
-
86
-
-
0028675999
-
Cytokines, inflammation, and brain injury: Role of tumor necrosis factor-alpha
-
7880718 1:STN:280:DyaK2M7os1emtQ%3D%3D
-
GZ Feuerstein T Liu FC Barone 1994 Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha Cerebrovasc Brain Metab Rev 6 341 360 7880718 1:STN:280:DyaK2M7os1emtQ%3D%3D
-
(1994)
Cerebrovasc Brain Metab Rev
, vol.6
, pp. 341-360
-
-
Feuerstein, G.Z.1
Liu, T.2
Barone, F.C.3
-
87
-
-
0035205575
-
Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: Possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase C
-
11739606 10.1046/j.1471-4159.2001.00652.x 1:CAS:528:DC%2BD3MXptFOhsLY%3D
-
BL Fiebich S Schleicher O Spleiss M Czygan M Hull 2001 Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase C J Neurochem 79 950 958 11739606 10.1046/j.1471-4159.2001.00652. x 1:CAS:528:DC%2BD3MXptFOhsLY%3D
-
(2001)
J Neurochem
, vol.79
, pp. 950-958
-
-
Fiebich, B.L.1
Schleicher, S.2
Spleiss, O.3
Czygan, M.4
Hull, M.5
-
88
-
-
26444553356
-
Hyperinsulinemia provokes synchronous increases in central inflammation and {beta}-amyloid in normal adults
-
16216936 10.1001/archneur.62.10.noc50112
-
MA Fishel GS Watson TJ Montine Q Wang PS Green JJ Kulstad DG Cook ER Peskind LD Baker D Goldgaber W Nie S Asthana SR Plymate MW Schwartz S Craft 2005 Hyperinsulinemia provokes synchronous increases in central inflammation and {beta}-amyloid in normal adults Arch Neurol 62 1539 1544 16216936 10.1001/archneur.62.10.noc50112
-
(2005)
Arch Neurol
, vol.62
, pp. 1539-1544
-
-
Fishel, M.A.1
Watson, G.S.2
Montine, T.J.3
Wang, Q.4
Green, P.S.5
Kulstad, J.J.6
Cook, D.G.7
Peskind, E.R.8
Baker, L.D.9
Goldgaber, D.10
Nie, W.11
Asthana, S.12
Plymate, S.R.13
Schwartz, M.W.14
Craft, S.15
-
89
-
-
33646841989
-
Beta-Amyloid stimulates murine postnatal and adult microglia cultures in a unique manner
-
16641245 10.1523/JNEUROSCI.4822-05.2006 1:CAS:528:DC%2BD28XksFWqurk%3D
-
AM Floden CK Combs 2006 beta-Amyloid stimulates murine postnatal and adult microglia cultures in a unique manner J Neurosci 26 4644 4648 16641245 10.1523/JNEUROSCI.4822-05.2006 1:CAS:528:DC%2BD28XksFWqurk%3D
-
(2006)
J Neurosci
, vol.26
, pp. 4644-4648
-
-
Floden, A.M.1
Combs, C.K.2
-
90
-
-
3242766671
-
Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
-
15269255 10.1523/JNEUROSCI.0901-04.2004 1:CAS:528:DC%2BD2cXmt1agu7c%3D
-
MI Fonseca J Zhou M Botto AJ Tenner 2004 Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease J Neurosci 24 6457 6465 15269255 10.1523/JNEUROSCI.0901-04.2004 1:CAS:528:DC%2BD2cXmt1agu7c%3D
-
(2004)
J Neurosci
, vol.24
, pp. 6457-6465
-
-
Fonseca, M.I.1
Zhou, J.2
Botto, M.3
Tenner, A.J.4
-
91
-
-
69249152289
-
Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease
-
19561098 10.4049/jimmunol.0901005 1:CAS:528:DC%2BD1MXotFWgsbg%3D
-
MI Fonseca RR Ager SH Chu O Yazan SD Sanderson FM Laferla SM Taylor TM Woodruff AJ Tenner 2009 Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease J Immunol 183 1375 1383 19561098 10.4049/jimmunol.0901005 1:CAS:528: DC%2BD1MXotFWgsbg%3D
-
(2009)
J Immunol
, vol.183
, pp. 1375-1383
-
-
Fonseca, M.I.1
Ager, R.R.2
Chu, S.H.3
Yazan, O.4
Sanderson, S.D.5
Laferla, F.M.6
Taylor, S.M.7
Woodruff, T.M.8
Tenner, A.J.9
-
92
-
-
0000892153
-
Pathology of Parkinsonism: A preliminary report of 24 cases
-
Forno L (1966) Pathology of Parkinsonism: a preliminary report of 24 cases. J Neurosurg (Supplement, Part II):266-271
-
(1966)
J Neurosurg
, Issue.SUPPL. AND PART II
, pp. 266-271
-
-
Forno, L.1
-
93
-
-
60949108812
-
Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice
-
19429012 10.1016/j.neulet.2009.01.075 1:CAS:528:DC%2BD1MXivVeiurs%3D
-
S Frank E Copanaki GJ Burbach UC Muller T Deller 2009 Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice Neurosci Lett 453 41 44 19429012 10.1016/j.neulet.2009.01.075 1:CAS:528:DC%2BD1MXivVeiurs%3D
-
(2009)
Neurosci Lett
, vol.453
, pp. 41-44
-
-
Frank, S.1
Copanaki, E.2
Burbach, G.J.3
Muller, U.C.4
Deller, T.5
-
95
-
-
0016717376
-
Histochemical characterization of a neocortical projection of the nucleus locus coeruleus in the squirrel monkey
-
810499 10.1002/cne.901640205 1:STN:280:DyaE28%2Fks1Kjtg%3D%3D
-
R Freedman SL Foote FE Bloom 1975 Histochemical characterization of a neocortical projection of the nucleus locus coeruleus in the squirrel monkey J Comp Neurol 164 209 231 810499 10.1002/cne.901640205 1:STN:280: DyaE28%2Fks1Kjtg%3D%3D
-
(1975)
J Comp Neurol
, vol.164
, pp. 209-231
-
-
Freedman, R.1
Foote, S.L.2
Bloom, F.E.3
-
96
-
-
0026660901
-
Production of macrophage colony-stimulating factor by astrocytes and brain macrophages
-
1430151 10.1016/0165-5728(92)90133-6 1:CAS:528:DyaK3sXnvFShsQ%3D%3D
-
K Frei K Nohava UV Malipiero C Schwerdel A Fontana 1992 Production of macrophage colony-stimulating factor by astrocytes and brain macrophages J Neuroimmunol 40 189 196 1430151 10.1016/0165-5728(92)90133-6 1:CAS:528:DyaK3sXnvFShsQ%3D%3D
-
(1992)
J Neuroimmunol
, vol.40
, pp. 189-196
-
-
Frei, K.1
Nohava, K.2
Malipiero, U.V.3
Schwerdel, C.4
Fontana, A.5
-
97
-
-
0024353437
-
Immunohistochemical analysis of the neurotoxic effects of DSP-4 identifies two populations of noradrenergic axon terminals
-
2747911 10.1016/0306-4522(89)90364-3 1:CAS:528:DyaL1MXkvFWrtb8%3D
-
JM Fritschy R Grzanna 1989 Immunohistochemical analysis of the neurotoxic effects of DSP-4 identifies two populations of noradrenergic axon terminals Neuroscience 30 181 197 2747911 10.1016/0306-4522(89)90364-3 1:CAS:528:DyaL1MXkvFWrtb8%3D
-
(1989)
Neuroscience
, vol.30
, pp. 181-197
-
-
Fritschy, J.M.1
Grzanna, R.2
-
98
-
-
77956956905
-
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
-
M Fuhrmann T Bittner CK Jung S Burgold RM Page G Mitteregger C Haass FM Laferla H Kretzschmar J Herms 2010 Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease Nat Neurosci 12 1358 1360
-
(2010)
Nat Neurosci
, vol.12
, pp. 1358-1360
-
-
Fuhrmann, M.1
Bittner, T.2
Jung, C.K.3
Burgold, S.4
Page, R.M.5
Mitteregger, G.6
Haass, C.7
Laferla, F.M.8
Kretzschmar, H.9
Herms, J.10
-
99
-
-
0026486613
-
Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures
-
1279698 10.1073/pnas.89.22.10945 1:CAS:528:DyaK3sXpvFGktw%3D%3D
-
E Galea DL Feinstein DJ Reis 1992 Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures Proc Natl Acad Sci USA 89 10945 10949 1279698 10.1073/pnas.89.22.10945 1:CAS:528:DyaK3sXpvFGktw%3D%3D
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10945-10949
-
-
Galea, E.1
Feinstein, D.L.2
Reis, D.J.3
-
100
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
7845465 10.1038/373523a0 1:CAS:528:DyaK2MXjs1Wns7w%3D
-
D Games D Adams R Alessandrini R Barbour P Berthelette C Blackwell T Carr J Clemens T Donaldson F Gillespie 1995 Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein Nature 373 523 527 7845465 10.1038/373523a0 1:CAS:528:DyaK2MXjs1Wns7w%3D
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
101
-
-
0029053689
-
Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines
-
7536777 1:CAS:528:DyaK2MXltF2nsr0%3D
-
P Gasque M Fontaine BP Morgan 1995 Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines J Immunol 154 4726 4733 7536777 1:CAS:528:DyaK2MXltF2nsr0%3D
-
(1995)
J Immunol
, vol.154
, pp. 4726-4733
-
-
Gasque, P.1
Fontaine, M.2
Morgan, B.P.3
-
102
-
-
0037119385
-
Norepinephrine increases i kappa B alpha expression in astrocytes
-
12050158 10.1074/jbc.M203256200 1:CAS:528:DC%2BD38XmsVKitb0%3D
-
V Gavrilyuk RC Dello MT Heneka D Pelligrino G Weinberg DL Feinstein 2002 Norepinephrine increases I kappa B alpha expression in astrocytes J Biol Chem 277 29662 29668 12050158 10.1074/jbc.M203256200 1:CAS:528:DC%2BD38XmsVKitb0%3D
-
(2002)
J Biol Chem
, vol.277
, pp. 29662-29668
-
-
Gavrilyuk, V.1
Dello, R.C.2
Heneka, M.T.3
Pelligrino, D.4
Weinberg, G.5
Feinstein, D.L.6
-
103
-
-
0026492005
-
Disease-specific patterns of locus coeruleus cell loss
-
1449247 10.1002/ana.410320510 1:STN:280:DyaK3s%2FotVaqtQ%3D%3D
-
DC German KF Manaye CL White III DJ Woodward DD McIntire WK Smith RN Kalaria DM Mann 1992 Disease-specific patterns of locus coeruleus cell loss Ann Neurol 32 667 676 1449247 10.1002/ana.410320510 1:STN:280:DyaK3s%2FotVaqtQ%3D%3D
-
(1992)
Ann Neurol
, vol.32
, pp. 667-676
-
-
German, D.C.1
Manaye, K.F.2
White III, C.L.3
Woodward, D.J.4
McIntire, D.D.5
Smith, W.K.6
Kalaria, R.N.7
Mann, D.M.8
-
104
-
-
0032943113
-
Chemokines and chemokine receptors in CNS pathology
-
10190685 10.3109/13550289909029740 1:CAS:528:DyaK1MXht1WmtLg%3D
-
AR Glabinski RM Ransohoff 1999 Chemokines and chemokine receptors in CNS pathology J Neurovirol 5 3 12 10190685 10.3109/13550289909029740 1:CAS:528:DyaK1MXht1WmtLg%3D
-
(1999)
J Neurovirol
, vol.5
, pp. 3-12
-
-
Glabinski, A.R.1
Ransohoff, R.M.2
-
105
-
-
0032504715
-
Cellular localization of tumor necrosis factor alpha following focal cerebral ischemia in mice
-
9729236 10.1016/S0006-8993(98)00489-2 1:CAS:528:DyaK1cXkslyht78%3D
-
C Gong Z Qin AL Betz XH Liu GY Yang 1998 Cellular localization of tumor necrosis factor alpha following focal cerebral ischemia in mice Brain Res 801 1 8 9729236 10.1016/S0006-8993(98)00489-2 1:CAS:528:DyaK1cXkslyht78%3D
-
(1998)
Brain Res
, vol.801
, pp. 1-8
-
-
Gong, C.1
Qin, Z.2
Betz, A.L.3
Liu, X.H.4
Yang, G.Y.5
-
106
-
-
0037300746
-
Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus
-
12663058 10.1016/S0891-0618(02)00100-X 1:CAS:528:DC%2BD3sXit12hurc%3D
-
AJ Graham MA Ray EK Perry E Jaros RH Perry SG Volsen S Bose N Evans J Lindstrom JA Court 2003 Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus J Chem Neuroanat 25 97 113 12663058 10.1016/S0891-0618(02)00100-X 1:CAS:528:DC%2BD3sXit12hurc%3D
-
(2003)
J Chem Neuroanat
, vol.25
, pp. 97-113
-
-
Graham, A.J.1
Ray, M.A.2
Perry, E.K.3
Jaros, E.4
Perry, R.H.5
Volsen, S.G.6
Bose, S.7
Evans, N.8
Lindstrom, J.9
Court, J.A.10
-
107
-
-
0035690770
-
Inflammatory factors are elevated in brain microvessels in Alzheimer's disease
-
11754990 10.1016/S0197-4580(01)00276-7 1:CAS:528:DC%2BD3MXptFylurs%3D
-
P Grammas R Ovase 2001 Inflammatory factors are elevated in brain microvessels in Alzheimer's disease Neurobiol Aging 22 837 842 11754990 10.1016/S0197-4580(01)00276-7 1:CAS:528:DC%2BD3MXptFylurs%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 837-842
-
-
Grammas, P.1
Ovase, R.2
-
108
-
-
74949127437
-
Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia
-
19838177 10.1038/nn.2432 1:CAS:528:DC%2BD1MXht1Ogsr3I
-
SA Grathwohl RE Kalin T Bolmont S Prokop G Winkelmann SA Kaeser J Odenthal R Radde T Eldh S Gandy A Aguzzi M Staufenbiel PM Mathews H Wolburg FL Heppner M Jucker 2009 Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia Nat Neurosci 12 1361 1363 19838177 10.1038/nn.2432 1:CAS:528:DC%2BD1MXht1Ogsr3I
-
(2009)
Nat Neurosci
, vol.12
, pp. 1361-1363
-
-
Grathwohl, S.A.1
Kalin, R.E.2
Bolmont, T.3
Prokop, S.4
Winkelmann, G.5
Kaeser, S.A.6
Odenthal, J.7
Radde, R.8
Eldh, T.9
Gandy, S.10
Aguzzi, A.11
Staufenbiel, M.12
Mathews, P.M.13
Wolburg, H.14
Heppner, F.L.15
Jucker, M.16
-
109
-
-
33847666729
-
IL-1 and the cytokine cycle in Alzheimer's disease
-
WST Griffin 2000 IL-1 and the cytokine cycle in Alzheimer's disease J Neurochem 74 S52
-
(2000)
J Neurochem
, vol.74
, pp. 52
-
-
Griffin, W.S.T.1
-
110
-
-
0031983986
-
Glial-neuronal interactions in Alzheimer's disease: The potential role of a 'cytokine cycle' in disease progression
-
9458167 10.1111/j.1750-3639.1998.tb00136.x 1:CAS:528:DyaK1cXjs1Ohu7k%3D
-
WS Griffin JG Sheng MC Royston SM Gentleman JE McKenzie DI Graham GW Roberts RE Mrak 1998 Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression Brain Pathol 8 65 72 9458167 10.1111/j.1750-3639.1998.tb00136.x 1:CAS:528:DyaK1cXjs1Ohu7k%3D
-
(1998)
Brain Pathol
, vol.8
, pp. 65-72
-
-
Griffin, W.S.1
Sheng, J.G.2
Royston, M.C.3
Gentleman, S.M.4
McKenzie, J.E.5
Graham, D.I.6
Roberts, G.W.7
Mrak, R.E.8
-
111
-
-
33846583006
-
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease
-
16574280 10.1016/j.neurobiolaging.2006.02.007 1:CAS:528: DC%2BD2sXhtlantrg%3D
-
A Grudzien P Shaw S Weintraub E Bigio DC Mash MM Mesulam 2007 Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease Neurobiol Aging 28 327 335 16574280 10.1016/j.neurobiolaging.2006.02.007 1:CAS:528:DC%2BD2sXhtlantrg%3D
-
(2007)
Neurobiol Aging
, vol.28
, pp. 327-335
-
-
Grudzien, A.1
Shaw, P.2
Weintraub, S.3
Bigio, E.4
Mash, D.C.5
Mesulam, M.M.6
-
112
-
-
0037101616
-
Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis
-
12122052 1:CAS:528:DC%2BD38XlsFOjsLo%3D
-
JT Guo J Yu D Grass FC de Beer MS Kindy 2002 Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis J Neurosci 22 5900 5909 12122052 1:CAS:528:DC%2BD38XlsFOjsLo%3D
-
(2002)
J Neurosci
, vol.22
, pp. 5900-5909
-
-
Guo, J.T.1
Yu, J.2
Grass, D.3
De Beer, F.C.4
Kindy, M.S.5
-
113
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
1383826 10.1038/359322a0 1:CAS:528:DyaK38XmtV2msro%3D
-
C Haass MG Schlossmacher AY Hung C Vigo-Pelfrey A Mellon BL Ostaszewski I Lieberburg EH Koo D Schenk DB Teplow 1992 Amyloid beta-peptide is produced by cultured cells during normal metabolism Nature 359 322 325 1383826 10.1038/359322a0 1:CAS:528:DyaK38XmtV2msro%3D
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
-
114
-
-
0036849018
-
Microglia as a source and target of cytokines
-
12379902 10.1002/glia.10161
-
UK Hanisch 2002 Microglia as a source and target of cytokines Glia 40 140 155 12379902 10.1002/glia.10161
-
(2002)
Glia
, vol.40
, pp. 140-155
-
-
Hanisch, U.K.1
-
115
-
-
35548986304
-
Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
-
17965659 10.1038/nn1997 1:CAS:528:DC%2BD2sXht1ajsbbE
-
UK Hanisch H Kettenmann 2007 Microglia: active sensor and versatile effector cells in the normal and pathologic brain Nat Neurosci 10 1387 1394 17965659 10.1038/nn1997 1:CAS:528:DC%2BD2sXht1ajsbbE
-
(2007)
Nat Neurosci
, vol.10
, pp. 1387-1394
-
-
Hanisch, U.K.1
Kettenmann, H.2
-
116
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
1763432 10.1016/0165-6147(91)90609-V 1:CAS:528:DyaK3MXmslKktr8%3D
-
J Hardy D Allsop 1991 Amyloid deposition as the central event in the aetiology of Alzheimer's disease Trends Pharmacol Sci 12 383 388 1763432 10.1016/0165-6147(91)90609-V 1:CAS:528:DyaK3MXmslKktr8%3D
-
(1991)
Trends Pharmacol Sci
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
117
-
-
0037440474
-
Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent
-
12509807 10.1002/glia.10178
-
M Hartlage-Rubsamen U Zeitschel J Apelt U Gartner H Franke T Stahl A Gunther R Schliebs M Penkowa V Bigl S Rossner 2003 Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent Glia 41 169 179 12509807 10.1002/glia.10178
-
(2003)
Glia
, vol.41
, pp. 169-179
-
-
Hartlage-Rubsamen, M.1
Zeitschel, U.2
Apelt, J.3
Gartner, U.4
Franke, H.5
Stahl, T.6
Gunther, A.7
Schliebs, R.8
Penkowa, M.9
Bigl, V.10
Rossner, S.11
-
118
-
-
34548316575
-
Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice
-
17724122 10.1083/jcb.200705042 1:CAS:528:DC%2BD2sXhtVSgtrjK
-
P He Z Zhong K Lindholm L Berning W Lee C Lemere M Staufenbiel R Li Y Shen 2007 Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice J Cell Biol 178 829 841 17724122 10.1083/jcb.200705042 1:CAS:528:DC%2BD2sXhtVSgtrjK
-
(2007)
J Cell Biol
, vol.178
, pp. 829-841
-
-
He, P.1
Zhong, Z.2
Lindholm, K.3
Berning, L.4
Lee, W.5
Lemere, C.6
Staufenbiel, M.7
Li, R.8
Shen, Y.9
-
119
-
-
72649097241
-
Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice
-
Hein AM, Stasko MR, Matousek SB, Scott-McKean JJ, Maier SF, Olschowka JA, Costa AC, O'Banion MK (2010) Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice. Brain Behav Immun 24(2):243-253
-
(2010)
Brain Behav Immun
, vol.24
, Issue.2
, pp. 243-253
-
-
Hein, A.M.1
Stasko, M.R.2
Matousek, S.B.3
Scott-Mckean, J.J.4
Maier, S.F.5
Olschowka, J.A.6
Costa, A.C.7
O'Banion, M.K.8
-
120
-
-
0035283321
-
Expression and function of inducible nitric oxide synthase in neurons
-
11240010 10.1016/S0165-5728(01)00246-6 1:CAS:528:DC%2BD3MXhs1CjtL4%3D
-
MT Heneka DL Feinstein 2001 Expression and function of inducible nitric oxide synthase in neurons J Neuroimmunol 114 8 18 11240010 10.1016/S0165- 5728(01)00246-6 1:CAS:528:DC%2BD3MXhs1CjtL4%3D
-
(2001)
J Neuroimmunol
, vol.114
, pp. 8-18
-
-
Heneka, M.T.1
Feinstein, D.L.2
-
121
-
-
33847613885
-
Inflammatory processes in Alzheimer's disease
-
17222916 10.1016/j.jneuroim.2006.11.017 1:CAS:528:DC%2BD2sXislejtLo%3D
-
MT Heneka MK O'Banion 2007 Inflammatory processes in Alzheimer's disease J Neuroimmunol 184 69 91 17222916 10.1016/j.jneuroim.2006.11.017 1:CAS:528:DC%2BD2sXislejtLo%3D
-
(2007)
J Neuroimmunol
, vol.184
, pp. 69-91
-
-
Heneka, M.T.1
O'Banion, M.K.2
-
122
-
-
2642605346
-
Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/ lipopolysaccharide
-
9648854 10.1046/j.1471-4159.1998.71010088.x 1:CAS:528:DyaK1cXktFams7s%3D
-
MT Heneka PA Loschmann M Gleichmann M Weller JB Schulz U Wullner T Klockgether 1998 Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide J Neurochem 71 88 94 9648854 10.1046/j.1471-4159.1998.71010088.x 1:CAS:528:DyaK1cXktFams7s%3D
-
(1998)
J Neurochem
, vol.71
, pp. 88-94
-
-
Heneka, M.T.1
Loschmann, P.A.2
Gleichmann, M.3
Weller, M.4
Schulz, J.B.5
Wullner, U.6
Klockgether, T.7
-
123
-
-
0033378706
-
Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase
-
10695726 10.1016/S0165-5728(99)00192-7 1:CAS:528:DC%2BD3cXltVehtA%3D%3D
-
MT Heneka DL Feinstein E Galea M Gleichmann U Wullner T Klockgether 1999 Peroxisome proliferator-activated receptor gamma agonists protect cerebellar
-
(1999)
J Neuroimmunol
, vol.100
, pp. 156-168
-
-
Heneka, M.T.1
Feinstein, D.L.2
Galea, E.3
Gleichmann, M.4
Wullner, U.5
Klockgether, T.6
-
124
-
-
0034666289
-
Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo
-
10995830 1:CAS:528:DC%2BD3cXmvVGhsrs%3D
-
MT Heneka T Klockgether DL Feinstein 2000 Peroxisome proliferator- activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo J Neurosci 20 6862 6867 10995830 1:CAS:528:DC%2BD3cXmvVGhsrs%3D
-
(2000)
J Neurosci
, vol.20
, pp. 6862-6867
-
-
Heneka, M.T.1
Klockgether, T.2
Feinstein, D.L.3
-
125
-
-
0034836593
-
Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease
-
11556547 1:CAS:528:DC%2BD3MXnt1SntL0%3D
-
MT Heneka H Wiesinger L Dumitrescu-Ozimek P Riederer DL Feinstein T Klockgether 2001 Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease J Neuropathol Exp Neurol 60 906 916 11556547 1:CAS:528:DC%2BD3MXnt1SntL0%3D
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 906-916
-
-
Heneka, M.T.1
Wiesinger, H.2
Dumitrescu-Ozimek, L.3
Riederer, P.4
Feinstein, D.L.5
Klockgether, T.6
-
126
-
-
0036546148
-
Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: Implications for Alzheimer's disease
-
11923407 1:CAS:528:DC%2BD38Xis1Wjs7s%3D
-
MT Heneka E Galea V Gavriluyk L Dumitrescu-Ozimek J Daeschner MK O'Banion G Weinberg T Klockgether DL Feinstein 2002 Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease J Neurosci 22 2434 2442 11923407 1:CAS:528:DC%2BD38Xis1Wjs7s%3D
-
(2002)
J Neurosci
, vol.22
, pp. 2434-2442
-
-
Heneka, M.T.1
Galea, E.2
Gavriluyk, V.3
Dumitrescu-Ozimek, L.4
Daeschner, J.5
O'Banion, M.K.6
Weinberg, G.7
Klockgether, T.8
Feinstein, D.L.9
-
127
-
-
0037387636
-
Noradrenergic depletion increases inflammatory responses in brain: Effects on IkappaB and HSP70 expression
-
12675915 10.1046/j.1471-4159.2003.01694.x 1:CAS:528:DC%2BD3sXjtlylsrg%3D
-
MT Heneka V Gavrilyuk GE Landreth MK O'Banion G Weinberg DL Feinstein 2003 Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression J Neurochem 85 387 398 12675915 10.1046/j.1471-4159.2003.01694.x 1:CAS:528:DC%2BD3sXjtlylsrg%3D
-
(2003)
J Neurochem
, vol.85
, pp. 387-398
-
-
Heneka, M.T.1
Gavrilyuk, V.2
Landreth, G.E.3
O'Banion, M.K.4
Weinberg, G.5
Feinstein, D.L.6
-
128
-
-
27644595378
-
Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice
-
16212664 10.1186/1742-2094-2-22 1:CAS:528:DC%2BD28XhsVejsrw%3D
-
MT Heneka M Sastre L Dumitrescu-Ozimek I Dewachter J Walter T Klockgether F Van Leuven 2005 Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice J Neuroinflammation 2 22 16212664 10.1186/1742-2094-2-22 1:CAS:528: DC%2BD28XhsVejsrw%3D
-
(2005)
J Neuroinflammation
, vol.2
, pp. 22
-
-
Heneka, M.T.1
Sastre, M.2
Dumitrescu-Ozimek, L.3
Dewachter, I.4
Walter, J.5
Klockgether, T.6
Van Leuven, F.7
-
129
-
-
20444499367
-
Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice
-
15817521 10.1093/brain/awh452
-
MT Heneka M Sastre L Dumitrescu-Ozimek A Hanke I Dewachter C Kuiperi K O'Banion T Klockgether F Van Leuven GE Landreth 2005 Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice Brain 128 1442 1453 15817521 10.1093/brain/awh452
-
(2005)
Brain
, vol.128
, pp. 1442-1453
-
-
Heneka, M.T.1
Sastre, M.2
Dumitrescu-Ozimek, L.3
Hanke, A.4
Dewachter, I.5
Kuiperi, C.6
O'Banion, K.7
Klockgether, T.8
Van Leuven, F.9
Landreth, G.E.10
-
130
-
-
32544449785
-
Locus Ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice
-
16452658 10.1523/JNEUROSCI.4236-05.2006 1:CAS:528:DC%2BD28XhsFaitrs%3D
-
MT Heneka M Ramanathan AH Jacobs L Dumitrescu-Ozimek A Bilkei-Gorzo T Debeir M Sastre N Galldiks A Zimmer M Hoehn WD Heiss T Klockgether M Staufenbiel 2006 Locus Ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice J Neurosci 26 1343 1354 16452658 10.1523/JNEUROSCI.4236-05.2006 1:CAS:528:DC%2BD28XhsFaitrs%3D
-
(2006)
J Neurosci
, vol.26
, pp. 1343-1354
-
-
Heneka, M.T.1
Ramanathan, M.2
Jacobs, A.H.3
Dumitrescu-Ozimek, L.4
Bilkei-Gorzo, A.5
Debeir, T.6
Sastre, M.7
Galldiks, N.8
Zimmer, A.9
Hoehn, M.10
Heiss, W.D.11
Klockgether, T.12
Staufenbiel, M.13
-
131
-
-
77950547609
-
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine
-
20231476 10.1073/pnas.0909586107
-
MT Heneka F Nadrigny T Regen A Martinez-Hernandez L Dumitrescu-Ozimek D Terwel D Jardanhazi-Kurutz J Walter F Kirchhoff UK Hanisch MP Kummer 2010 Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine Proc Natl Acad Sci USA 107 6058 6063 20231476 10.1073/pnas.0909586107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6058-6063
-
-
Heneka, M.T.1
Nadrigny, F.2
Regen, T.3
Martinez-Hernandez, A.4
Dumitrescu-Ozimek, L.5
Terwel, D.6
Jardanhazi-Kurutz, D.7
Walter, J.8
Kirchhoff, F.9
Hanisch, U.K.10
Kummer, M.P.11
-
132
-
-
0028180518
-
A model for beta-amyloid aggregation and neurotoxicity based on free-radical generation by the peptide-relevance to Alzheimer-disease
-
8159737 10.1073/pnas.91.8.3270 1:CAS:528:DyaK2cXivFGrt7s%3D
-
K Hensley JM Carney MP Mattson M Aksenova M Harris JF Wu RA Floyd DA Butterfield 1994 A model for beta-amyloid aggregation and neurotoxicity based on free-radical generation by the peptide-relevance to Alzheimer-disease Proc Natl Acad Sci USA 91 3270 3274 8159737 10.1073/pnas.91.8.3270 1:CAS:528: DyaK2cXivFGrt7s%3D
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
133
-
-
1542722942
-
Hematopoietic origin of microglial and perivascular cells in brain
-
15026252 10.1016/j.expneurol.2003.11.005 1:CAS:528:DC%2BD2cXitFKnsbc%3D
-
DC Hess T Abe WD Hill AM Studdard J Carothers M Masuya PA Fleming CJ Drake M Ogawa 2004 Hematopoietic origin of microglial and perivascular cells in brain Exp Neurol 186 134 144 15026252 10.1016/j.expneurol.2003.11.005 1:CAS:528:DC%2BD2cXitFKnsbc%3D
-
(2004)
Exp Neurol
, vol.186
, pp. 134-144
-
-
Hess, D.C.1
Abe, T.2
Hill, W.D.3
Studdard, A.M.4
Carothers, J.5
Masuya, M.6
Fleming, P.A.7
Drake, C.J.8
Ogawa, M.9
-
134
-
-
0032892888
-
Chemokine and chemokine receptor expression in the central nervous system
-
10190686 10.3109/13550289909029741 1:CAS:528:DyaK1MXht1WmtLk%3D
-
J Hesselgesser R Horuk 1999 Chemokine and chemokine receptor expression in the central nervous system J Neurovirol 5 13 26 10190686 10.3109/ 13550289909029741 1:CAS:528:DyaK1MXht1WmtLk%3D
-
(1999)
J Neurovirol
, vol.5
, pp. 13-26
-
-
Hesselgesser, J.1
Horuk, R.2
-
135
-
-
0027932457
-
Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS
-
7520256 10.1016/0896-6273(94)90362-X 1:CAS:528:DyaK2cXlslKktrY%3D
-
SJ Hewett CA Csernansky DW Choi 1994 Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS Neuron 13 487 494 7520256 10.1016/0896-6273(94)90362-X 1:CAS:528:DyaK2cXlslKktrY%3D
-
(1994)
Neuron
, vol.13
, pp. 487-494
-
-
Hewett, S.J.1
Csernansky, C.A.2
Choi, D.W.3
-
136
-
-
0031028141
-
Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain
-
9037082 10.1073/pnas.94.4.1500 1:CAS:528:DyaK2sXhtl2nt70%3D
-
CJ Heyser E Masliah A Samimi IL Campbell LH Gold 1997 Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain Proc Natl Acad Sci USA 94 1500 1505 9037082 10.1073/pnas.94.4.1500 1:CAS:528:DyaK2sXhtl2nt70%3D
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1500-1505
-
-
Heyser, C.J.1
Masliah, E.2
Samimi, A.3
Campbell, I.L.4
Gold, L.H.5
-
137
-
-
51149120624
-
Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice
-
18701698 10.1523/JNEUROSCI.0616-08.2008 1:CAS:528:DC%2BD1cXhtVaktLnE
-
SE Hickman EK Allison J El Khoury 2008 Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice J Neurosci 28 8354 8360 18701698 10.1523/JNEUROSCI.0616-08.2008 1:CAS:528:DC%2BD1cXhtVaktLnE
-
(2008)
J Neurosci
, vol.28
, pp. 8354-8360
-
-
Hickman, S.E.1
Allison, E.K.2
El Khoury, J.3
-
138
-
-
0035100231
-
Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease
-
11255454 10.1001/archneur.58.3.487 1:STN:280:DC%2BD3M7pvVChsQ%3D%3D
-
L Ho D Purohit V Haroutunian JD Luterman F Willis J Naslund JD Buxbaum RC Mohs PS Aisen GM Pasinetti 2001 Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease Arch Neurol 58 487 492 11255454 10.1001/archneur.58.3.487 1:STN:280:DC%2BD3M7pvVChsQ%3D%3D
-
(2001)
Arch Neurol
, vol.58
, pp. 487-492
-
-
Ho, L.1
Purohit, D.2
Haroutunian, V.3
Luterman, J.D.4
Willis, F.5
Naslund, J.6
Buxbaum, J.D.7
Mohs, R.C.8
Aisen, P.S.9
Pasinetti, G.M.10
-
139
-
-
21044448540
-
Mechanisms of cell signaling and inflammation in Alzheimer's disease
-
15853747 10.2174/1568010053586237 1:CAS:528:DC%2BD2MXlsFelsbY%3D
-
GJ Ho R Drego E Hakimian E Masliah 2005 Mechanisms of cell signaling and inflammation in Alzheimer's disease Curr Drug Targets Inflamm Allergy 4 247 256 15853747 10.2174/1568010053586237 1:CAS:528:DC%2BD2MXlsFelsbY%3D
-
(2005)
Curr Drug Targets Inflamm Allergy
, vol.4
, pp. 247-256
-
-
Ho, G.J.1
Drego, R.2
Hakimian, E.3
Masliah, E.4
-
141
-
-
33847640046
-
Neuronal immunoreactivity for COX-2 and phosphorylation of prb precede P38 MAPK activation and neurofibrillary changes in ad temporal cortex
-
10.1016/S0197-4580(04)81366-6
-
J Hoozemans R Veerhuis A Rozemuller T Arendt P Eikelenboom 2004 Neuronal immunoreactivity for COX-2 and phosphorylation of prb precede P38 MAPK activation and neurofibrillary changes in ad temporal cortex Neurobiol Aging 25 S416 10.1016/S0197-4580(04)81366-6
-
(2004)
Neurobiol Aging
, vol.25
, pp. 416
-
-
Hoozemans, J.1
Veerhuis, R.2
Rozemuller, A.3
Arendt, T.4
Eikelenboom, P.5
-
142
-
-
0033559312
-
Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: Astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome
-
10068656 1:CAS:528:DyaK1MXhvFSmtLo%3D
-
K Hori PR Burd K Furuke J Kutza KA Weih KA Clouse 1999 Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome Blood 93 1843 1850 10068656 1:CAS:528:DyaK1MXhvFSmtLo%3D
-
(1999)
Blood
, vol.93
, pp. 1843-1850
-
-
Hori, K.1
Burd, P.R.2
Furuke, K.3
Kutza, J.4
Weih, K.A.5
Clouse, K.A.6
-
143
-
-
0031569227
-
Expression of chemokine receptors by subsets of neurons in the central nervous system
-
9058825 1:CAS:528:DyaK2sXhvVOmu78%3D
-
R Horuk AW Martin ZX Wang L Schweitzer A Gerassimides HH Guo ZH Lu J Hesselgesser HD Perez J Kim J Parker TJ Hadley SC Peiper 1997 Expression of chemokine receptors by subsets of neurons in the central nervous system J Immunol 158 2882 2890 9058825 1:CAS:528:DyaK2sXhvVOmu78%3D
-
(1997)
J Immunol
, vol.158
, pp. 2882-2890
-
-
Horuk, R.1
Martin, A.W.2
Wang, Z.X.3
Schweitzer, L.4
Gerassimides, A.5
Guo, H.H.6
Lu, Z.H.7
Hesselgesser, J.8
Perez, H.D.9
Kim, J.10
Parker, J.11
Hadley, T.J.12
Peiper, S.C.13
-
144
-
-
67650561188
-
Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor
-
19407341 10.1074/jbc.M109.003269 1:CAS:528:DC%2BD1MXnslegu74%3D
-
T Hoshino T Namba M Takehara T Nakaya Y Sugimoto W Araki S Narumiya T Suzuki T Mizushima 2009 Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor J Biol Chem 284 18493 18502 19407341 10.1074/jbc.M109.003269 1:CAS:528:DC%2BD1MXnslegu74%3D
-
(2009)
J Biol Chem
, vol.284
, pp. 18493-18502
-
-
Hoshino, T.1
Namba, T.2
Takehara, M.3
Nakaya, T.4
Sugimoto, Y.5
Araki, W.6
Narumiya, S.7
Suzuki, T.8
Mizushima, T.9
-
145
-
-
0035936004
-
Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease
-
In t'Veld, Ruitenberg A, Hofman A, Launer LJ, van Duijn CM, Stijnen T, Breteler MM, Stricker BH (2001) Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease. N Engl J Med 345:1515-1521
-
(2001)
N Engl J Med
, vol.345
, pp. 1515-1521
-
-
T'Veld Ruitenberg, A.1
Hofman, A.2
Launer, L.J.3
Van Duijn, C.M.4
Stijnen, T.5
Breteler, M.M.6
Stricker, B.H.7
-
146
-
-
28744458578
-
CpG-containing oligodeoxynucleotide promotes microglial cell uptake of amyloid beta 1-42 peptide by up-regulating the expression of the G-protein-coupled receptor mFPR2
-
16219804 1:CAS:528:DC%2BD2MXhtlSmu7%2FP
-
P Iribarren KQ Chen JY Hu WH Gong EH Cho S Lockett B Uranchimeg JM Wang 2005 CpG-containing oligodeoxynucleotide promotes microglial cell uptake of amyloid beta 1-42 peptide by up-regulating the expression of the G-protein-coupled receptor mFPR2 FASEB J 19 2032 2034 16219804 1:CAS:528:DC%2BD2MXhtlSmu7%2FP
-
(2005)
FASEB J
, vol.19
, pp. 2032-2034
-
-
Iribarren, P.1
Chen, K.Q.2
Hu, J.Y.3
Gong, W.H.4
Cho, E.H.5
Lockett, S.6
Uranchimeg, B.7
Wang, J.M.8
-
147
-
-
0030988629
-
Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease
-
9225377 10.1111/j.1440-1819.1997.tb02375.x 1:STN:280:DyaK2szmvVOlsQ%3D%3D
-
K Ishizuka T Kimura R Igata-yi S Katsuragi J Takamatsu T Miyakawa 1997 Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease Psychiatry Clin Neurosci 51 135 138 9225377 10.1111/j.1440-1819.1997.tb02375.x 1:STN:280:DyaK2szmvVOlsQ%3D%3D
-
(1997)
Psychiatry Clin Neurosci
, vol.51
, pp. 135-138
-
-
Ishizuka, K.1
Kimura, T.2
Igata-Yi, R.3
Katsuragi, S.4
Takamatsu, J.5
Miyakawa, T.6
-
148
-
-
0024436506
-
Relationship of Microglia and Astrocytes to Amyloid Deposits of Alzheimer-Disease
-
2808689 10.1016/0165-5728(89)90115-X 1:STN:280:DyaK3c%2FjslGnsg%3D%3D
-
S Itagaki PL McGeer H Akiyama S Zhu D Selkoe 1989 Relationship of Microglia and Astrocytes to Amyloid Deposits of Alzheimer-Disease J Neuroimmunol 24 173 182 2808689 10.1016/0165-5728(89)90115-X 1:STN:280: DyaK3c%2FjslGnsg%3D%3D
-
(1989)
J Neuroimmunol
, vol.24
, pp. 173-182
-
-
Itagaki, S.1
McGeer, P.L.2
Akiyama, H.3
Zhu, S.4
Selkoe, D.5
-
149
-
-
0020513205
-
Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of Alzheimer's type
-
6633940 10.1016/0304-3940(83)90171-4 1:CAS:528:DyaL3sXltlCgsbY%3D
-
LL Iversen MN Rossor GP Reynolds R Hills M Roth CQ Mountjoy SL Foote JH Morrison FE Bloom 1983 Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of Alzheimer's type Neurosci Lett 39 95 100 6633940 10.1016/0304-3940(83)90171-4 1:CAS:528:DyaL3sXltlCgsbY%3D
-
(1983)
Neurosci Lett
, vol.39
, pp. 95-100
-
-
Iversen, L.L.1
Rossor, M.N.2
Reynolds, G.P.3
Hills, R.4
Roth, M.5
Mountjoy, C.Q.6
Foote, S.L.7
Morrison, J.H.8
Bloom, F.E.9
-
150
-
-
58149181978
-
Fibrillar amyloid-beta peptides activate microglia via TLR2: Implications for Alzheimer's disease
-
18981147 1:CAS:528:DC%2BD1cXhtlaisrjE
-
M Jana CA Palencia K Pahan 2008 Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease J Immunol 181 7254 7262 18981147 1:CAS:528:DC%2BD1cXhtlaisrjE
-
(2008)
J Immunol
, vol.181
, pp. 7254-7262
-
-
Jana, M.1
Palencia, C.A.2
Pahan, K.3
-
151
-
-
57149101898
-
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice
-
18974297 10.2353/ajpath.2008.080528 1:CAS:528:DC%2BD1MXkt1Cqsw%3D%3D
-
MC Janelsins MA Mastrangelo KM Park KL Sudol WC Narrow S Oddo FM Laferla LM Callahan HJ Federoff WJ Bowers 2008 Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice Am J Pathol 173 1768 1782 18974297 10.2353/ajpath.2008.080528 1:CAS:528:DC%2BD1MXkt1Cqsw%3D%3D
-
(2008)
Am J Pathol
, vol.173
, pp. 1768-1782
-
-
Janelsins, M.C.1
Mastrangelo, M.A.2
Park, K.M.3
Sudol, K.L.4
Narrow, W.C.5
Oddo, S.6
Laferla, F.M.7
Callahan, L.M.8
Federoff, H.J.9
Bowers, W.J.10
-
152
-
-
58149216131
-
Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic
-
18987201 10.1523/JNEUROSCI.3024-08.2008 1:CAS:528:DC%2BD1cXhtlOgt7%2FK
-
S Jimenez D Baglietto-Vargas C Caballero I Moreno-Gonzalez M Torres R Sanchez-Varo D Ruano M Vizuete A Gutierrez J Vitorica 2008 Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic J Neurosci 28 11650 11661 18987201 10.1523/JNEUROSCI.3024-08.2008 1:CAS:528:DC%2BD1cXhtlOgt7%2FK
-
(2008)
J Neurosci
, vol.28
, pp. 11650-11661
-
-
Jimenez, S.1
Baglietto-Vargas, D.2
Caballero, C.3
Moreno-Gonzalez, I.4
Torres, M.5
Sanchez-Varo, R.6
Ruano, D.7
Vizuete, M.8
Gutierrez, A.9
Vitorica, J.10
-
153
-
-
0024445028
-
Adrenergic receptors in aging and Alzheimer's disease: Increased beta 2-receptors in prefrontal cortex and hippocampus
-
2553864 10.1111/j.1471-4159.1989.tb09242.x 1:CAS:528:DyaK3cXhvFGktg%3D%3D
-
RN Kalaria AC Andorn M Tabaton PJ Whitehouse SI Harik JR Unnerstall 1989 Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus J Neurochem 53 1772 1781 2553864 10.1111/j.1471-4159.1989.tb09242.x 1:CAS:528:DyaK3cXhvFGktg%3D%3D
-
(1989)
J Neurochem
, vol.53
, pp. 1772-1781
-
-
Kalaria, R.N.1
Andorn, A.C.2
Tabaton, M.3
Whitehouse, P.J.4
Harik, S.I.5
Unnerstall, J.R.6
-
154
-
-
0028990941
-
APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism
-
7670501 10.1038/ng0895-486 1:CAS:528:DyaK2MXnsVWks7w%3D
-
MI Kamboh DK Sanghera RE Ferrell ST DeKosky 1995 APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism Nat Genet 10 486 488 7670501 10.1038/ng0895-486 1:CAS:528:DyaK2MXnsVWks7w%3D
-
(1995)
Nat Genet
, vol.10
, pp. 486-488
-
-
Kamboh, M.I.1
Sanghera, D.K.2
Ferrell, R.E.3
Dekosky, S.T.4
-
155
-
-
0032887341
-
Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2
-
10487857 1:CAS:528:DyaK1MXmsVCrurw%3D
-
KA Kelley L Ho D Winger J Freire-Moar CB Borelli PS Aisen GM Pasinetti 1999 Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2 Am J Pathol 155 995 1004 10487857 1:CAS:528:DyaK1MXmsVCrurw%3D
-
(1999)
Am J Pathol
, vol.155
, pp. 995-1004
-
-
Kelley, K.A.1
Ho, L.2
Winger, D.3
Freire-Moar, J.4
Borelli, C.B.5
Aisen, P.S.6
Pasinetti, G.M.7
-
156
-
-
0347756655
-
Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
-
14691478 10.1038/ni1018 1:CAS:528:DC%2BD3sXhtVWhtrzL
-
D Kelly JI Campbell TP King G Grant EA Jansson AG Coutts S Pettersson S Conway 2004 Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA Nat Immunol 5 104 112 14691478 10.1038/ni1018 1:CAS:528:DC%2BD3sXhtVWhtrzL
-
(2004)
Nat Immunol
, vol.5
, pp. 104-112
-
-
Kelly, D.1
Campbell, J.I.2
King, T.P.3
Grant, G.4
Jansson, E.A.5
Coutts, A.G.6
Pettersson, S.7
Conway, S.8
-
157
-
-
11844269951
-
Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis
-
15649489 10.1016/j.expneurol.2004.10.007 1:CAS:528:DC%2BD2MXksFKisw%3D%3D
-
M Kiaei K Kipiani JY Chen NY Calingasan MF Beal 2005 Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis Exp Neurol 191 331 336 15649489 10.1016/j.expneurol.2004.10.007 1:CAS:528:DC%2BD2MXksFKisw%3D%3D
-
(2005)
Exp Neurol
, vol.191
, pp. 331-336
-
-
Kiaei, M.1
Kipiani, K.2
Chen, J.Y.3
Calingasan, N.Y.4
Beal, M.F.5
-
158
-
-
0033608169
-
Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains
-
9920782 10.1006/bbrc.1998.9981 1:CAS:528:DyaK1MXhtVegsbk%3D
-
Y Kitamura S Shimohama H Koike J Kakimura Y Matsuoka Y Nomura PJ Gebicke-Haerter T Taniguchi 1999 Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains Biochem Biophys Res Commun 254 582 586 9920782 10.1006/bbrc.1998.9981 1:CAS:528:DyaK1MXhtVegsbk%3D
-
(1999)
Biochem Biophys Res Commun
, vol.254
, pp. 582-586
-
-
Kitamura, Y.1
Shimohama, S.2
Koike, H.3
Kakimura, J.4
Matsuoka, Y.5
Nomura, Y.6
Gebicke-Haerter, P.J.7
Taniguchi, T.8
-
159
-
-
25644456097
-
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
-
16192374 10.1523/JNEUROSCI.2868-05.2005 1:CAS:528:DC%2BD2MXhtVOqs7rP
-
M Kitazawa S Oddo TR Yamasaki KN Green FM Laferla 2005 Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease J Neurosci 25 8843 8853 16192374 10.1523/JNEUROSCI.2868-05.2005 1:CAS:528:DC%2BD2MXhtVOqs7rP
-
(2005)
J Neurosci
, vol.25
, pp. 8843-8853
-
-
Kitazawa, M.1
Oddo, S.2
Yamasaki, T.R.3
Green, K.N.4
Laferla, F.M.5
-
160
-
-
0028321529
-
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
-
8041794 10.1073/pnas.91.15.7355 1:CAS:528:DyaK2cXmsFajtb0%3D
-
SA Kliewer BM Forman B Blumberg ES Ong U Borgmeyer DJ Mangelsdorf K Umesono RM Evans 1994 Differential expression and activation of a family of murine peroxisome proliferator-activated receptors Proc Natl Acad Sci USA 91 7355 7359 8041794 10.1073/pnas.91.15.7355 1:CAS:528:DyaK2cXmsFajtb0%3D
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7355-7359
-
-
Kliewer, S.A.1
Forman, B.M.2
Blumberg, B.3
Ong, E.S.4
Borgmeyer, U.5
Mangelsdorf, D.J.6
Umesono, K.7
Evans, R.M.8
-
161
-
-
7744235869
-
Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism
-
15525768 10.1523/JNEUROSCI.2557-04.2004 1:CAS:528:DC%2BD2cXhtVWhtrfF
-
J Koenigsknecht G Landreth 2004 Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism J Neurosci 24 9838 9846 15525768 10.1523/JNEUROSCI.2557-04.2004 1:CAS:528:DC%2BD2cXhtVWhtrfF
-
(2004)
J Neurosci
, vol.24
, pp. 9838-9846
-
-
Koenigsknecht, J.1
Landreth, G.2
-
162
-
-
0030222037
-
Microglia: A sensor for pathological events in the CNS
-
8843599 10.1016/0166-2236(96)10049-7 1:STN:280:DyaK2s%2FgtVGitg%3D%3D
-
GW Kreutzberg 1996 Microglia: a sensor for pathological events in the CNS Trends Neurosci 19 312 318 8843599 10.1016/0166-2236(96)10049-7 1:STN:280:DyaK2s%2FgtVGitg%3D%3D
-
(1996)
Trends Neurosci
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
163
-
-
61349096009
-
Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
-
19251629 10.1126/science.1169096 1:CAS:528:DC%2BD1MXit1eltbY%3D
-
KV Kuchibhotla CR Lattarulo BT Hyman BJ Bacskai 2009 Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice Science 323 1211 1215 19251629 10.1126/science.1169096 1:CAS:528: DC%2BD1MXit1eltbY%3D
-
(2009)
Science
, vol.323
, pp. 1211-1215
-
-
Kuchibhotla, K.V.1
Lattarulo, C.R.2
Hyman, B.T.3
Bacskai, B.J.4
-
164
-
-
0035693506
-
Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease
-
11755002 10.1016/S0197-4580(01)00296-2 1:CAS:528:DC%2BD3MXptFylu7k%3D
-
GE Landreth MT Heneka 2001 Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease Neurobiol Aging 22 937 944 11755002 10.1016/S0197-4580(01)00296-2 1:CAS:528: DC%2BD3MXptFylu7k%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 937-944
-
-
Landreth, G.E.1
Heneka, M.T.2
-
165
-
-
0032707107
-
Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: Association with Hirano bodies, neurofibrillary tangles, and senile plaques
-
10560659 10.1097/00005072-199911000-00006 1:CAS:528:DyaK1MXnvVartrc%3D
-
SC Lee ML Zhao A Hirano DW Dickson 1999 Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques J Neuropathol Exp Neurol 58 1163 1169 10560659 10.1097/00005072-199911000-00006 1:CAS:528:DyaK1MXnvVartrc%3D
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1163-1169
-
-
Lee, S.C.1
Zhao, M.L.2
Hirano, A.3
Dickson, D.W.4
-
167
-
-
0036644961
-
Cytokines, chemokines, and cytokine receptors in human microglia
-
12111820 10.1002/jnr.10253 1:CAS:528:DC%2BD38Xlt1Kqs7g%3D
-
YB Lee A Nagai SU Kim 2002 Cytokines, chemokines, and cytokine receptors in human microglia J Neurosci Res 69 94 103 12111820 10.1002/jnr.10253 1:CAS:528:DC%2BD38Xlt1Kqs7g%3D
-
(2002)
J Neurosci Res
, vol.69
, pp. 94-103
-
-
Lee, Y.B.1
Nagai, A.2
Kim, S.U.3
-
168
-
-
4444271426
-
Mechanisms involved in prostaglandin E2-mediated neuroprotection against TNF-alpha: Possible involvement of multiple signal transduction and beta-catenin/T-cell factor
-
15342193 10.1016/j.jneuroim.2004.05.012 1:CAS:528:DC%2BD2cXntlSnsro%3D
-
EO Lee YJ Shin YH Chong 2004 Mechanisms involved in prostaglandin E2-mediated neuroprotection against TNF-alpha: possible involvement of multiple signal transduction and beta-catenin/T-cell factor J Neuroimmunol 155 21 31 15342193 10.1016/j.jneuroim.2004.05.012 1:CAS:528:DC%2BD2cXntlSnsro%3D
-
(2004)
J Neuroimmunol
, vol.155
, pp. 21-31
-
-
Lee, E.O.1
Shin, Y.J.2
Chong, Y.H.3
-
169
-
-
0031013395
-
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
9013583 10.1074/jbc.272.6.3406 1:CAS:528:DyaK2sXhtFeltLc%3D
-
JM Lehmann JM Lenhard BB Oliver GM Ringold SA Kliewer 1997 Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs J Biol Chem 272 3406 3410 9013583 10.1074/jbc.272.6.3406 1:CAS:528:DyaK2sXhtFeltLc%3D
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
170
-
-
0034121698
-
Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene
-
10848596 10.1128/MCB.20.13.4699-4707.2000 1:CAS:528:DC%2BD3cXksVOjurs%3D
-
M Li G Pascual CK Glass 2000 Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene Mol Cell Biol 20 4699 4707 10848596 10.1128/MCB.20.13.4699-4707.2000 1:CAS:528: DC%2BD3cXksVOjurs%3D
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4699-4707
-
-
Li, M.1
Pascual, G.2
Glass, C.K.3
-
171
-
-
0037336701
-
Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway
-
12629164 1:CAS:528:DC%2BD3sXjtFylt7c%3D
-
YK Li L Liu SW Barger WST Griffin 2003 Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway J Neurosci 23 1605 1611 12629164 1:CAS:528:DC%2BD3sXjtFylt7c%3D
-
(2003)
J Neurosci
, vol.23
, pp. 1605-1611
-
-
Li, Y.K.1
Liu, L.2
Barger, S.W.3
Griffin, W.S.T.4
-
172
-
-
27744462871
-
Deletion of the prostaglandin E-2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease
-
16267225 10.1523/JNEUROSCI.3591-05.2005 1:CAS:528:DC%2BD2MXht1Wqt77I
-
XB Liang Q Wang T Hand LJ Wu RM Breyer TJ Montine K Andreasson 2005 Deletion of the prostaglandin E-2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease J Neurosci 25 10180 10187 16267225 10.1523/JNEUROSCI.3591-05.2005 1:CAS:528:DC%2BD2MXht1Wqt77I
-
(2005)
J Neurosci
, vol.25
, pp. 10180-10187
-
-
Liang, X.B.1
Wang, Q.2
Hand, T.3
Wu, L.J.4
Breyer, R.M.5
Montine, T.J.6
Andreasson, K.7
-
173
-
-
0034254924
-
Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease
-
10908610 1:CAS:528:DC%2BD3cXlt1Gltbk%3D
-
GP Lim F Yang T Chu P Chen W Beech B Teter T Tran O Ubeda KH Ashe SA Frautschy GM Cole 2000 Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease J Neurosci 20 5709 5714 10908610 1:CAS:528:DC%2BD3cXlt1Gltbk%3D
-
(2000)
J Neurosci
, vol.20
, pp. 5709-5714
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Chen, P.4
Beech, W.5
Teter, B.6
Tran, T.7
Ubeda, O.8
Ashe, K.H.9
Frautschy, S.A.10
Cole, G.M.11
-
174
-
-
0035691115
-
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
-
11755007 10.1016/S0197-4580(01)00299-8 1:CAS:528:DC%2BD3MXptFyksrw%3D
-
GP Lim F Yang T Chu E Gahtan O Ubeda W Beech JB Overmier K Hsiao-Ashec SA Frautschy GM Cole 2001 Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice Neurobiol Aging 22 983 991 11755007 10.1016/S0197-4580(01)00299-8 1:CAS:528:DC%2BD3MXptFyksrw%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 983-991
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Gahtan, E.4
Ubeda, O.5
Beech, W.6
Overmier, J.B.7
Hsiao-Ashec, K.8
Frautschy, S.A.9
Cole, G.M.10
-
175
-
-
23444455475
-
Beta-Amyloid protein structure determines the nature of cytokine release from rat microglia
-
16055942 10.1385/JMN:27:1:001 1:CAS:528:DC%2BD2MXotFantLY%3D
-
C Lindberg MLB Selenica A Westlind-Danielsson M Schultzberg 2005 beta-Amyloid protein structure determines the nature of cytokine release from rat microglia J Mol Neurosci 27 1 12 16055942 10.1385/JMN:27:1:001 1:CAS:528:DC%2BD2MXotFantLY%3D
-
(2005)
J Mol Neurosci
, vol.27
, pp. 1-12
-
-
Lindberg, C.1
Selenica, M.L.B.2
Westlind-Danielsson, A.3
Schultzberg, M.4
-
176
-
-
0037215645
-
Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
-
12490568 10.1124/jpet.102.035048 1:CAS:528:DC%2BD3sXhtF2qug%3D%3D
-
B Liu JS Hong 2003 Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention J Pharmacol Exp Ther 304 1 7 12490568 10.1124/jpet.102.035048 1:CAS:528:DC%2BD3sXhtF2qug%3D%3D
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1-7
-
-
Liu, B.1
Hong, J.S.2
-
177
-
-
23444448277
-
LPS receptor (CD14): A receptor for phagocytosis of Alzheimer's amyloid peptide
-
15857927 10.1093/brain/awh531
-
Y Liu S Walter M Stagi D Cherny M Letiembre W Schulz-Schaeffer H Heine B Penke H Neumann K Fassbender 2005 LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide Brain 128 1778 1789 15857927 10.1093/brain/awh531
-
(2005)
Brain
, vol.128
, pp. 1778-1789
-
-
Liu, Y.1
Walter, S.2
Stagi, M.3
Cherny, D.4
Letiembre, M.5
Schulz-Schaeffer, W.6
Heine, H.7
Penke, B.8
Neumann, H.9
Fassbender, K.10
-
178
-
-
7044254509
-
Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation
-
15448688 10.1038/nm1112 1:CAS:528:DC%2BD2cXnvFyntbk%3D
-
A Lleo O Berezovska L Herl S Raju A Deng BJ Bacskai MP Frosch M Irizarry BT Hyman 2004 Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation Nat Med 10 1065 1066 15448688 10.1038/nm1112 1:CAS:528:DC%2BD2cXnvFyntbk%3D
-
(2004)
Nat Med
, vol.10
, pp. 1065-1066
-
-
Lleo, A.1
Berezovska, O.2
Herl, L.3
Raju, S.4
Deng, A.5
Bacskai, B.J.6
Frosch, M.P.7
Irizarry, M.8
Hyman, B.T.9
-
179
-
-
22244456028
-
Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures
-
15998280 10.1111/j.1471-4159.2005.03188.x 1:CAS:528:DC%2BD2MXmsVarsL8%3D
-
M Lotz S Ebert H Esselmann AI Iliev M Prinz N Wiazewicz J Wiltfang J Gerber R Nau 2005 Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures J Neurochem 94 289 298 15998280 10.1111/j.1471-4159.2005.03188.x 1:CAS:528:DC%2BD2MXmsVarsL8%3D
-
(2005)
J Neurochem
, vol.94
, pp. 289-298
-
-
Lotz, M.1
Ebert, S.2
Esselmann, H.3
Iliev, A.I.4
Prinz, M.5
Wiazewicz, N.6
Wiltfang, J.7
Gerber, J.8
Nau, R.9
-
180
-
-
0034948192
-
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro
-
11424194 10.1002/glia.1072 1:STN:280:DC%2BD3Mzmt1aluw%3D%3D
-
LF Lue R Rydel EF Brigham LB Yang H Hampel GM Murphy L Brachova SD Yan DG Walker Y Shen J Rogers 2001 Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro Glia 35 72 79 11424194 10.1002/glia.1072 1:STN:280:DC%2BD3Mzmt1aluw%3D%3D
-
(2001)
Glia
, vol.35
, pp. 72-79
-
-
Lue, L.F.1
Rydel, R.2
Brigham, E.F.3
Yang, L.B.4
Hampel, H.5
Murphy, G.M.6
Brachova, L.7
Yan, S.D.8
Walker, D.G.9
Shen, Y.10
Rogers, J.11
-
181
-
-
0031453714
-
Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex
-
9452008 10.1002/(SICI)1097-4547(19971215)50:6 <937::AID-JNR4>3.0. CO;2-E 1:CAS:528:DyaK1cXis1Krtg%3D%3D
-
WJ Lukiw NG Bazan 1997 Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex J Neurosci Res 50 937 945 9452008 10.1002/(SICI)1097-4547(19971215)50:6<937::AID-JNR4>3.0.CO;2-E 1:CAS:528:DyaK1cXis1Krtg%3D%3D
-
(1997)
J Neurosci Res
, vol.50
, pp. 937-945
-
-
Lukiw, W.J.1
Bazan, N.G.2
-
182
-
-
57649119790
-
An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells
-
18801740 10.1074/jbc.M805371200 1:CAS:528:DC%2BD1cXhtlCjsLfF
-
WJ Lukiw Y Zhao JG Cui 2008 An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells J Biol Chem 283 31315 31322 18801740 10.1074/jbc.M805371200 1:CAS:528:DC%2BD1cXhtlCjsLfF
-
(2008)
J Biol Chem
, vol.283
, pp. 31315-31322
-
-
Lukiw, W.J.1
Zhao, Y.2
Cui, J.G.3
-
183
-
-
0032509889
-
Chemokines-chemotactic cytokines that mediate inflammation
-
9459648 10.1056/NEJM199802123380706 1:CAS:528:DyaK1cXht1Wrsrc%3D
-
AD Luster 1998 Chemokines-chemotactic cytokines that mediate inflammation N Engl J Med 338 436 445 9459648 10.1056/NEJM199802123380706 1:CAS:528:DyaK1cXht1Wrsrc%3D
-
(1998)
N Engl J Med
, vol.338
, pp. 436-445
-
-
Luster, A.D.1
-
184
-
-
0028173205
-
Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein e promote assembly of Alzheimer beta-protein into filaments
-
7969426 10.1038/372092a0 1:CAS:528:DyaK2cXmvFygur0%3D
-
J Ma A Yee HB Brewer Jr S Das H Potter 1994 Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments Nature 372 92 94 7969426 10.1038/372092a0 1:CAS:528:DyaK2cXmvFygur0%3D
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, Jr.H.B.3
Das, S.4
Potter, H.5
-
185
-
-
0035696167
-
Postmortem studies of the effect of anti-inflammatory drugs on Alzheimer-type pathology and associated inflammation
-
11754988 10.1016/S0197-4580(01)00304-9 1:CAS:528:DC%2BD3MXptFylur0%3D
-
IR Mackenzie 2001 Postmortem studies of the effect of anti-inflammatory drugs on Alzheimer-type pathology and associated inflammation Neurobiol Aging 22 819 822 11754988 10.1016/S0197-4580(01)00304-9 1:CAS:528:DC%2BD3MXptFylur0%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 819-822
-
-
MacKenzie, I.R.1
-
186
-
-
0031900411
-
Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging
-
9566383 1:CAS:528:DyaK1cXivVajt78%3D
-
IR Mackenzie DG Munoz 1998 Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging Neurology 50 986 990 9566383 1:CAS:528:DyaK1cXivVajt78%3D
-
(1998)
Neurology
, vol.50
, pp. 986-990
-
-
MacKenzie, I.R.1
Munoz, D.G.2
-
187
-
-
0027494752
-
Electrophysiological changes accompanying DSP-4 lesions of rat locus coeruleus neurons
-
8313164 10.1016/0006-8993(93)90972-P 1:CAS:528:DyaK2cXnsVOgtA%3D%3D
-
DS Magnuson WA Staines KC Marshall 1993 Electrophysiological changes accompanying DSP-4 lesions of rat locus coeruleus neurons Brain Res 628 317 320 8313164 10.1016/0006-8993(93)90972-P 1:CAS:528:DyaK2cXnsVOgtA%3D%3D
-
(1993)
Brain Res
, vol.628
, pp. 317-320
-
-
Magnuson, D.S.1
Staines, W.A.2
Marshall, K.C.3
-
188
-
-
11844255779
-
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
-
15649704 10.1016/j.nbd.2004.09.009 1:CAS:528:DC%2BD2MXkslOgtg%3D%3D
-
TM Malm M Koistinaho M Parepalo T Vatanen A Ooka S Karlsson J Koistinaho 2005 Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice Neurobiol Dis 18 134 142 15649704 10.1016/j.nbd.2004.09.009 1:CAS:528:DC%2BD2MXkslOgtg%3D%3D
-
(2005)
Neurobiol Dis
, vol.18
, pp. 134-142
-
-
Malm, T.M.1
Koistinaho, M.2
Parepalo, M.3
Vatanen, T.4
Ooka, A.5
Karlsson, S.6
Koistinaho, J.7
-
189
-
-
0018857625
-
Changes in the monoamine containing neurones of the human CNS in senile dementia
-
6155966 10.1192/bjp.136.6.533 1:STN:280:DyaL3c3itFKmuw%3D%3D
-
DM Mann J Lincoln PO Yates JE Stamp S Toper 1980 Changes in the monoamine containing neurones of the human CNS in senile dementia Br J Psychiatry 136 533 541 6155966 10.1192/bjp.136.6.533 1:STN:280:DyaL3c3itFKmuw%3D%3D
-
(1980)
Br J Psychiatry
, vol.136
, pp. 533-541
-
-
Mann, D.M.1
Lincoln, J.2
Yates, P.O.3
Stamp, J.E.4
Toper, S.5
-
190
-
-
0020059233
-
The noradrenergic system in Alzheimer and multi-infarct dementias
-
7069423 10.1136/jnnp.45.2.113 1:STN:280:DyaL387mvFCgtg%3D%3D
-
DM Mann PO Yates J Hawkes 1982 The noradrenergic system in Alzheimer and multi-infarct dementias J Neurol Neurosurg Psychiatry 45 113 119 7069423 10.1136/jnnp.45.2.113 1:STN:280:DyaL387mvFCgtg%3D%3D
-
(1982)
J Neurol Neurosurg Psychiatry
, vol.45
, pp. 113-119
-
-
Mann, D.M.1
Yates, P.O.2
Hawkes, J.3
-
191
-
-
0023001412
-
The topography of cell loss from locus caeruleus in Alzheimer's disease
-
3794754 10.1016/0022-510X(86)90179-6 1:STN:280:DyaL2s%2FosFKrtA%3D%3D
-
B Marcyniuk DM Mann PO Yates 1986 The topography of cell loss from locus caeruleus in Alzheimer's disease J Neurol Sci 76 335 345 3794754 10.1016/0022-510X(86)90179-6 1:STN:280:DyaL2s%2FosFKrtA%3D%3D
-
(1986)
J Neurol Sci
, vol.76
, pp. 335-345
-
-
Marcyniuk, B.1
Mann, D.M.2
Yates, P.O.3
-
192
-
-
1942516961
-
Noradrenergic mechanisms in neurodegenerative diseases: A theory
-
15063099 10.1016/j.brainresrev.2004.02.002 1:CAS:528:DC%2BD2cXivVWlur4%3D
-
MR Marien FC Colpaert AC Rosenquist 2004 Noradrenergic mechanisms in neurodegenerative diseases: a theory Brain Res Brain Res Rev 45 38 78 15063099 10.1016/j.brainresrev.2004.02.002 1:CAS:528:DC%2BD2cXivVWlur4%3D
-
(2004)
Brain Res Brain Res Rev
, vol.45
, pp. 38-78
-
-
Marien, M.R.1
Colpaert, F.C.2
Rosenquist, A.C.3
-
193
-
-
0035067311
-
Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease
-
11290552 1:CAS:528:DC%2BD3MXjtVWhsbY%3D
-
Y Matsuoka M Picciano B Malester J LaFrancois C Zehr JM Daeschner JA Olschowka MI Fonseca MK O'Banion AJ Tenner CA Lemere K Duff 2001 Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease Am J Pathol 158 1345 1354 11290552 1:CAS:528:DC%2BD3MXjtVWhsbY%3D
-
(2001)
Am J Pathol
, vol.158
, pp. 1345-1354
-
-
Matsuoka, Y.1
Picciano, M.2
Malester, B.3
Lafrancois, J.4
Zehr, C.5
Daeschner, J.M.6
Olschowka, J.A.7
Fonseca, M.I.8
O'Banion, M.K.9
Tenner, A.J.10
Lemere, C.A.11
Duff, K.12
-
194
-
-
0025853857
-
Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in monkeys: A possible role for the locus coeruleus in the progression of Parkinson's disease
-
1870701 10.1016/0306-4522(91)90345-O 1:STN:280:DyaK3MzjtlOktw%3D%3D
-
M Mavridis AD Degryse AJ Lategan MR Marien FC Colpaert 1991 Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in monkeys: a possible role for the locus coeruleus in the progression of Parkinson's disease Neuroscience 41 507 523 1870701 10.1016/0306-4522(91)90345-O 1:STN:280:DyaK3MzjtlOktw%3D%3D
-
(1991)
Neuroscience
, vol.41
, pp. 507-523
-
-
Mavridis, M.1
Degryse, A.D.2
Lategan, A.J.3
Marien, M.R.4
Colpaert, F.C.5
-
195
-
-
0842322738
-
Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia
-
14715958 10.1523/JNEUROSCI.4485-03.2004 1:CAS:528:DC%2BD2cXotF2ltQ%3D%3D
-
L McCullough L Wu N Haughey X Liang T Hand Q Wang RM Breyer K Andreasson 2004 Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia J Neurosci 24 257 268 14715958 10.1523/JNEUROSCI.4485-03.2004 1:CAS:528: DC%2BD2cXotF2ltQ%3D%3D
-
(2004)
J Neurosci
, vol.24
, pp. 257-268
-
-
McCullough, L.1
Wu, L.2
Haughey, N.3
Liang, X.4
Hand, T.5
Wang, Q.6
Breyer, R.M.7
Andreasson, K.8
-
196
-
-
0035835451
-
Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: A case-control study
-
11273064 10.1016/S0140-6736(00)04008-3 1:CAS:528:DC%2BD3MXhtFaktr0%3D
-
SM McCusker MD Curran KB Dynan CD McCullagh DD Urquhart D Middleton CC Patterson SP McIlroy AP Passmore 2001 Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study Lancet 357 436 439 11273064 10.1016/S0140-6736(00)04008-3 1:CAS:528:DC%2BD3MXhtFaktr0%3D
-
(2001)
Lancet
, vol.357
, pp. 436-439
-
-
McCusker, S.M.1
Curran, M.D.2
Dynan, K.B.3
McCullagh, C.D.4
Urquhart, D.D.5
Middleton, D.6
Patterson, C.C.7
McIlroy, S.P.8
Passmore, A.P.9
-
197
-
-
0029610011
-
The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
-
8866675 10.1016/0165-0173(95)00011-9 1:STN:280:DyaK2s%2FitVaqsg%3D%3D
-
PL McGeer EG McGeer 1995 The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases Brain Res Brain Res Rev 21 195 218 8866675 10.1016/0165-0173(95)00011-9 1:STN:280:DyaK2s%2FitVaqsg%3D%3D
-
(1995)
Brain Res Brain Res Rev
, vol.21
, pp. 195-218
-
-
McGeer, P.L.1
McGeer, E.G.2
-
198
-
-
0032731763
-
Brain inflammation in Alzheimer disease and the therapeutic implications
-
10526088 1:CAS:528:DyaK1MXntFSisbg%3D
-
EG McGeer PL McGeer 1999 Brain inflammation in Alzheimer disease and the therapeutic implications Curr Pharm Des 5 821 836 10526088 1:CAS:528: DyaK1MXntFSisbg%3D
-
(1999)
Curr Pharm des
, vol.5
, pp. 821-836
-
-
McGeer, E.G.1
McGeer, P.L.2
-
199
-
-
0036841667
-
The possible role of complement activation in Alzheimer disease
-
12421685 10.1016/S1471-4914(02)02422-X 1:CAS:528:DC%2BD38XotlygsLo%3D
-
PL McGeer EG McGeer 2002 The possible role of complement activation in Alzheimer disease Trends Mol Med 8 519 523 12421685 10.1016/S1471-4914(02)02422- X 1:CAS:528:DC%2BD38XotlygsLo%3D
-
(2002)
Trends Mol Med
, vol.8
, pp. 519-523
-
-
McGeer, P.L.1
McGeer, E.G.2
-
200
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
8757015 1:CAS:528:DyaK28Xls1Gltrw%3D
-
PL McGeer M Schulzer EG McGeer 1996 Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies Neurology 47 425 432 8757015 1:CAS:528:DyaK28Xls1Gltrw%3D
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
201
-
-
0032891880
-
Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35]
-
10378868 10.1016/S0165-5728(98)00188-X 1:CAS:528:DyaK1MXhslahtA%3D%3D
-
L Meda P Baron E Prat E Scarpini G Scarlato MA Cassatella F Rossi 1999 Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35] J Neuroimmunol 93 45 52 10378868 10.1016/S0165-5728(98)00188-X 1:CAS:528:DyaK1MXhslahtA%3D%3D
-
(1999)
J Neuroimmunol
, vol.93
, pp. 45-52
-
-
Meda, L.1
Baron, P.2
Prat, E.3
Scarpini, E.4
Scarlato, G.5
Cassatella, M.A.6
Rossi, F.7
-
202
-
-
0034237388
-
Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology
-
10817926 10.1016/S0736-5748(00)00012-5 1:CAS:528:DC%2BD3cXks1Sqs78%3D
-
G Mehlhorn M Hollborn R Schliebs 2000 Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology Int J Dev Neurosci 18 423 431 10817926 10.1016/S0736- 5748(00)00012-5 1:CAS:528:DC%2BD3cXks1Sqs78%3D
-
(2000)
Int J Dev Neurosci
, vol.18
, pp. 423-431
-
-
Mehlhorn, G.1
Hollborn, M.2
Schliebs, R.3
-
203
-
-
38949123792
-
Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease
-
Meyer-Luehmann M, Spires-Jones TL, Prada C, Garcia-Alloza M, de Calignon A, Rozkalne A, Koenigsknecht-Talboo J, Holtzman DM, Bacskai BJ, Hyman BT (2008) Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. Nature 451:720-724
-
(2008)
Nature
, vol.451
, pp. 720-724
-
-
Meyer-Luehmann, M.1
Spires-Jones, T.L.2
Prada, C.3
Garcia-Alloza, M.4
De Calignon, A.5
Rozkalne, A.6
Koenigsknecht-Talboo, J.7
Holtzman, D.M.8
Bacskai, B.J.9
Hyman, B.T.10
-
204
-
-
36448955070
-
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
-
18026096 10.1038/nn2015 1:CAS:528:DC%2BD2sXhtlKltLbI
-
A Mildner H Schmidt M Nitsche D Merkler UK Hanisch M Mack M Heikenwalder W Bruck J Priller M Prinz 2007 Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions Nat Neurosci 10 1544 1553 18026096 10.1038/nn2015 1:CAS:528:DC%2BD2sXhtlKltLbI
-
(2007)
Nat Neurosci
, vol.10
, pp. 1544-1553
-
-
Mildner, A.1
Schmidt, H.2
Nitsche, M.3
Merkler, D.4
Hanisch, U.K.5
MacK, M.6
Heikenwalder, M.7
Bruck, W.8
Priller, J.9
Prinz, M.10
-
205
-
-
0030994412
-
Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs
-
9182946 10.1111/j.1460-9568.1997.tb01444.x 1:STN:280:DyaK2szisF2gtg%3D%3D
-
L Minghetti E Polazzi A Nicolini C Creminon G Levi 1997 Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs Eur J Neurosci 9 934 940 9182946 10.1111/j.1460-9568.1997.tb01444.x 1:STN:280:DyaK2szisF2gtg%3D%3D
-
(1997)
Eur J Neurosci
, vol.9
, pp. 934-940
-
-
Minghetti, L.1
Polazzi, E.2
Nicolini, A.3
Creminon, C.4
Levi, G.5
-
206
-
-
0026663451
-
Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions
-
1382661 10.1097/00001756-199206000-00020 1:CAS:528:DyaK38Xlt1Gju7o%3D
-
C Moncada D Lekieffre B Arvin B Meldrum 1992 Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions Neuroreport 3 530 532 1382661 10.1097/00001756-199206000-00020 1:CAS:528:DyaK38Xlt1Gju7o%3D
-
(1992)
Neuroreport
, vol.3
, pp. 530-532
-
-
Moncada, C.1
Lekieffre, D.2
Arvin, B.3
Meldrum, B.4
-
208
-
-
17844378699
-
Regulation of prostaglandin E-2 synthesis after brain irradiation
-
15850932 10.1016/j.ijrobp.2005.01.035 1:CAS:528:DC%2BD2MXjsFKjsbw%3D
-
AH Moore JA Olschowka JP Williams P Okunieff MK O'Banion 2005 Regulation of prostaglandin E-2 synthesis after brain irradiation Int J Radiat Oncol Biol Phys 62 267 272 15850932 10.1016/j.ijrobp.2005.01.035 1:CAS:528: DC%2BD2MXjsFKjsbw%3D
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.62
, pp. 267-272
-
-
Moore, A.H.1
Olschowka, J.A.2
Williams, J.P.3
Okunieff, P.4
O'Banion, M.K.5
-
209
-
-
70449518278
-
Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory
-
Moore AH, Wu M, Shaftel SS, Graham KA, O'Banion MK (2009) Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory. Neuroscience 164(4):1484-1495
-
(2009)
Neuroscience
, vol.164
, Issue.4
, pp. 1484-1495
-
-
Moore, A.H.1
Wu, M.2
Shaftel, S.S.3
Graham, K.A.4
O'Banion, M.K.5
-
210
-
-
19344361883
-
Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models
-
15688088 10.1038/sj.npp.1300668 1:CAS:528:DC%2BD2MXltlWmtrY%3D
-
T Morihara B Teter F Yang GP Lim S Boudinot FD Boudinot SA Frautschy GM Cole 2005 Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models Neuropsychopharmacology 30 1111 1120 15688088 10.1038/sj.npp.1300668 1:CAS:528:DC%2BD2MXltlWmtrY%3D
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1111-1120
-
-
Morihara, T.1
Teter, B.2
Yang, F.3
Lim, G.P.4
Boudinot, S.5
Boudinot, F.D.6
Frautschy, S.A.7
Cole, G.M.8
-
211
-
-
0036434305
-
Acute neuroinflammation exacerbates excitotoxicity in rat hippocampus in vivo
-
12429214 10.1006/exnr.2002.7991 1:CAS:528:DC%2BD38XosVantbk%3D
-
K Morimoto T Murasugi T Oda 2002 Acute neuroinflammation exacerbates excitotoxicity in rat hippocampus in vivo Exp Neurol 177 95 104 12429214 10.1006/exnr.2002.7991 1:CAS:528:DC%2BD38XosVantbk%3D
-
(2002)
Exp Neurol
, vol.177
, pp. 95-104
-
-
Morimoto, K.1
Murasugi, T.2
Oda, T.3
-
212
-
-
0035690976
-
Interleukin-1, neuroinflammation, and Alzheimer's disease
-
11754997 10.1016/S0197-4580(01)00287-1 1:CAS:528:DC%2BD3MXptFylu7w%3D
-
RE Mrak WS Griffin 2001 Interleukin-1, neuroinflammation, and Alzheimer's disease Neurobiol Aging 22 903 908 11754997 10.1016/S0197-4580(01)00287-1 1:CAS:528:DC%2BD3MXptFylu7w%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 903-908
-
-
Mrak, R.E.1
Griffin, W.S.2
-
213
-
-
0033562393
-
Nature of the retrograde signal from injured nerves that induces interleukin-6 mRNA in neurons
-
10234011 1:CAS:528:DyaK1MXjtV2rt7s%3D
-
PG Murphy LS Borthwick RS Johnston G Kuchel PM Richardson 1999 Nature of the retrograde signal from injured nerves that induces interleukin-6 mRNA in neurons J Neurosci 19 3791 3800 10234011 1:CAS:528:DyaK1MXjtV2rt7s%3D
-
(1999)
J Neurosci
, vol.19
, pp. 3791-3800
-
-
Murphy, P.G.1
Borthwick, L.S.2
Johnston, R.S.3
Kuchel, G.4
Richardson, P.M.5
-
214
-
-
0032523168
-
Evidence that increased hippocampal expression of the cytokine interleukin-1 beta is a common trigger for age- and stress-induced impairments in long-term potentiation
-
9526014 1:CAS:528:DyaK1cXis1ejtb4%3D
-
CA Murray MA Lynch 1998 Evidence that increased hippocampal expression of the cytokine interleukin-1 beta is a common trigger for age- and stress-induced impairments in long-term potentiation J Neurosci 18 2974 2981 9526014 1:CAS:528:DyaK1cXis1ejtb4%3D
-
(1998)
J Neurosci
, vol.18
, pp. 2974-2981
-
-
Murray, C.A.1
Lynch, M.A.2
-
215
-
-
14744296610
-
Inflammatory process in Parkinson's disease: Role for cytokines
-
15777250 10.2174/1381612053381620 1:CAS:528:DC%2BD2MXhvVChurk%3D
-
T Nagatsu M Sawada 2005 Inflammatory process in Parkinson's disease: role for cytokines Curr Pharm Des 11 999 1016 15777250 10.2174/1381612053381620 1:CAS:528:DC%2BD2MXhvVChurk%3D
-
(2005)
Curr Pharm des
, vol.11
, pp. 999-1016
-
-
Nagatsu, T.1
Sawada, M.2
-
216
-
-
0037427384
-
Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
-
12706236 10.1016/S0006-8993(03)02361-8 1:CAS:528:DC%2BD3sXivFequ7k%3D
-
RG Nagele MR D'Andrea H Lee V Venkataraman HY Wang 2003 Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains Brain Res 971 197 209 12706236 10.1016/S0006-8993(03)02361-8 1:CAS:528:DC%2BD3sXivFequ7k%3D
-
(2003)
Brain Res
, vol.971
, pp. 197-209
-
-
Nagele, R.G.1
D'Andrea, M.R.2
Lee, H.3
Venkataraman, V.4
Wang, H.Y.5
-
217
-
-
0032823306
-
Prostanoid receptors: Structures, properties, and functions
-
10508233 1:CAS:528:DyaK1MXmvVymtL0%3D
-
S Narumiya Y Sugimoto F Ushikubi 1999 Prostanoid receptors: structures, properties, and functions Physiol Rev 79 1193 1226 10508233 1:CAS:528: DyaK1MXmvVymtL0%3D
-
(1999)
Physiol Rev
, vol.79
, pp. 1193-1226
-
-
Narumiya, S.1
Sugimoto, Y.2
Ushikubi, F.3
-
218
-
-
0036546185
-
Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
-
11960303 10.1038/sj.gene.6363832 1:CAS:528:DC%2BD38XivFOrurw%3D
-
C Natarajan JJ Bright 2002 Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation Genes Immun 3 59 70 11960303 10.1038/sj.gene.6363832 1:CAS:528:DC%2BD38XivFOrurw%3D
-
(2002)
Genes Immun
, vol.3
, pp. 59-70
-
-
Natarajan, C.1
Bright, J.J.2
-
219
-
-
0034053173
-
Association of interleukin-1 gene polymorphisms with Alzheimer's disease
-
10716257 10.1002/1531-8249(200003)47:3 <365::AID-ANA13>3.0.CO;2-G 1:CAS:528:DC%2BD3cXitFaktLc%3D
-
JA Nicoll RE Mrak DI Graham J Stewart G Wilcock S MacGowan MM Esiri LS Murray D Dewar S Love T Moss WS Griffin 2000 Association of interleukin-1 gene polymorphisms with Alzheimer's disease Ann Neurol 47 365 368 10716257 10.1002/1531-8249(200003)47:3<365::AID-ANA13>3.0.CO;2-G 1:CAS:528:DC%2BD3cXitFaktLc%3D
-
(2000)
Ann Neurol
, vol.47
, pp. 365-368
-
-
Nicoll, J.A.1
Mrak, R.E.2
Graham, D.I.3
Stewart, J.4
Wilcock, G.5
MacGowan, S.6
Esiri, M.M.7
Murray, L.S.8
Dewar, D.9
Love, S.10
Moss, T.11
Griffin, W.S.12
-
220
-
-
0035341427
-
Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma
-
11311328 10.1016/S0165-5728(01)00285-5 1:CAS:528:DC%2BD3MXislGks7Y%3D
-
M Niino K Iwabuchi S Kikuchi M Ato T Morohashi A Ogata K Tashiro K Onoe 2001 Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma J Neuroimmunol 116 40 48 11311328 10.1016/S0165-5728(01)00285-5 1:CAS:528:DC%2BD3MXislGks7Y%3D
-
(2001)
J Neuroimmunol
, vol.116
, pp. 40-48
-
-
Niino, M.1
Iwabuchi, K.2
Kikuchi, S.3
Ato, M.4
Morohashi, T.5
Ogata, A.6
Tashiro, K.7
Onoe, K.8
-
221
-
-
0025742695
-
DSP4 treatment worsens hippocampal pyramidal cell damage after transient ischemia
-
1656318 10.1016/0306-4522(91)90300-D 1:CAS:528:DyaK3MXkvFSht7k%3D
-
K Nishino CS Lin JK Morse JN Davis 1991 DSP4 treatment worsens hippocampal pyramidal cell damage after transient ischemia Neuroscience 43 361 367 1656318 10.1016/0306-4522(91)90300-D 1:CAS:528:DyaK3MXkvFSht7k%3D
-
(1991)
Neuroscience
, vol.43
, pp. 361-367
-
-
Nishino, K.1
Lin, C.S.2
Morse, J.K.3
Davis, J.N.4
-
222
-
-
0032896588
-
Cyclooxygenase-2: Molecular biology, pharmacology, and neurobiology
-
10223523
-
MK O'Banion 1999 Cyclooxygenase-2: Molecular biology, pharmacology, and neurobiology Crit Rev Neurobiol 13 45 82 10223523
-
(1999)
Crit Rev Neurobiol
, vol.13
, pp. 45-82
-
-
O'Banion, M.K.1
-
223
-
-
0029953089
-
Interleukin-1 beta induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures
-
8632179 10.1046/j.1471-4159.1996.66062532.x
-
MK O'Banion JC Miller JW Chang MD Kaplan PD Coleman 1996 Interleukin-1 beta induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures J Neurochem 66 2532 2540 8632179 10.1046/j.1471-4159.1996. 66062532.x
-
(1996)
J Neurochem
, vol.66
, pp. 2532-2540
-
-
O'Banion, M.K.1
Miller, J.C.2
Chang, J.W.3
Kaplan, M.D.4
Coleman, P.D.5
-
224
-
-
0030395410
-
Decreased expression of prostaglandin G/H synthase-2 (PGHS-2) in Alzheimer's disease brain
-
9321949
-
MK O'Banion JW Chang PD Coleman 1997 Decreased expression of prostaglandin G/H synthase-2 (PGHS-2) in Alzheimer's disease brain Adv Exp Med Biol 407 171 177 9321949
-
(1997)
Adv Exp Med Biol
, vol.407
, pp. 171-177
-
-
O'Banion, M.K.1
Chang, J.W.2
Coleman, P.D.3
-
225
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular A beta and synaptic dysfunction
-
12895417 10.1016/S0896-6273(03)00434-3 1:CAS:528:DC%2BD3sXmsFOksro%3D
-
S Oddo A Caccamo JD Shepherd MP Murphy TE Golde R Kayed R Metherate MP Mattson Y Akbari FM Laferla 2003 Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular A beta and synaptic dysfunction Neuron 39 409 421 12895417 10.1016/S0896-6273(03)00434-3 1:CAS:528:DC%2BD3sXmsFOksro%3D
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
Laferla, F.M.10
-
226
-
-
33144487701
-
Temporal profile of amyloid-beta (A beta) oligomerization in an in vivo model of Alzheimer disease-A link between A beta and tau pathology
-
16282321 10.1074/jbc.M507892200 1:CAS:528:DC%2BD28XksFOlsg%3D%3D
-
S Oddo A Caccamo L Tran MP Lambert CG Glabe WL Klein FM Laferla 2006 Temporal profile of amyloid-beta (A beta) oligomerization in an in vivo model of Alzheimer disease-A link between A beta and tau pathology J Biol Chem 281 1599 1604 16282321 10.1074/jbc.M507892200 1:CAS:528:DC%2BD28XksFOlsg%3D%3D
-
(2006)
J Biol Chem
, vol.281
, pp. 1599-1604
-
-
Oddo, S.1
Caccamo, A.2
Tran, L.3
Lambert, M.P.4
Glabe, C.G.5
Klein, W.L.6
Laferla, F.M.7
-
227
-
-
0030951257
-
Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: Specific localization in affected neurones and axons
-
9175105 10.1097/00001756-199703240-00020 1:CAS:528:DyaK2sXjvF2isrc%3D
-
A Oka S Takashima 1997 Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons Neuroreport 8 1161 1164 9175105 10.1097/00001756-199703240-00020 1:CAS:528:DyaK2sXjvF2isrc%3D
-
(1997)
Neuroreport
, vol.8
, pp. 1161-1164
-
-
Oka, A.1
Takashima, S.2
-
228
-
-
60449109146
-
Toll-like receptors in neurodegeneration
-
18822314 10.1016/j.brainresrev.2008.09.001 1:CAS:528:DC%2BD1MXit1SgsrY%3D
-
E Okun KJ Griffioen JD Lathia SC Tang MP Mattson TV Arumugam 2009 Toll-like receptors in neurodegeneration Brain Res Rev 59 278 292 18822314 10.1016/j.brainresrev.2008.09.001 1:CAS:528:DC%2BD1MXit1SgsrY%3D
-
(2009)
Brain Res Rev
, vol.59
, pp. 278-292
-
-
Okun, E.1
Griffioen, K.J.2
Lathia, J.D.3
Tang, S.C.4
Mattson, M.P.5
Arumugam, T.V.6
-
229
-
-
0020528723
-
Decreased activity of locus coeruleus neurons in the rat after DSP-4 treatment
-
6633969 10.1016/0304-3940(83)90096-4 1:CAS:528:DyaL3sXlvVygurg%3D
-
HR Olpe J Laszlo DJ Dooley J Heid MW Steinmann 1983 Decreased activity of locus coeruleus neurons in the rat after DSP-4 treatment Neurosci Lett 40 81 84 6633969 10.1016/0304-3940(83)90096-4 1:CAS:528:DyaL3sXlvVygurg%3D
-
(1983)
Neurosci Lett
, vol.40
, pp. 81-84
-
-
Olpe, H.R.1
Laszlo, J.2
Dooley, D.J.3
Heid, J.4
Steinmann, M.W.5
-
230
-
-
0344141389
-
Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1beta and interleukin-6 in the rat hippocampus after transient global ischemia
-
10218914 10.1016/S0304-3940(99)00043-9 1:CAS:528:DyaK1MXhvVClt7c%3D
-
O Orzylowska B Oderfeld-Nowak M Zaremba S Januszewski M Mossakowski 1999 Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1beta and interleukin-6 in the rat hippocampus after transient global ischemia Neurosci Lett 263 72 76 10218914 10.1016/S0304-3940(99)00043-9 1:CAS:528:DyaK1MXhvVClt7c%3D
-
(1999)
Neurosci Lett
, vol.263
, pp. 72-76
-
-
Orzylowska, O.1
Oderfeld-Nowak, B.2
Zaremba, M.3
Januszewski, S.4
Mossakowski, M.5
-
231
-
-
0033562337
-
Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity
-
10321830 10.1002/(SICI)1097-4644(19990601)73:3 <303::AID-JCB2>3.0. CO;2-2 1:CAS:528:DyaK1MXivVejs7w%3D
-
H Osaka P Mukherjee PS Aisen GM Pasinetti 1999 Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity J Cell Biochem 73 303 311 10321830 10.1002/(SICI)1097-4644(19990601)73:3<303::AID- JCB2>3.0.CO;2-2 1:CAS:528:DyaK1MXivVejs7w%3D
-
(1999)
J Cell Biochem
, vol.73
, pp. 303-311
-
-
Osaka, H.1
Mukherjee, P.2
Aisen, P.S.3
Pasinetti, G.M.4
-
232
-
-
17844392320
-
Cytokine and chemokine inter-regulation in the inflamed or injured CNS
-
15850656 10.1016/j.brainresrev.2004.12.007 1:CAS:528:DC%2BD2MXjs1Cmurw%3D
-
T Owens AA Babcock JM Millward H Toft-Hansen 2005 Cytokine and chemokine inter-regulation in the inflamed or injured CNS Brain Res Brain Res Rev 48 178 184 15850656 10.1016/j.brainresrev.2004.12.007 1:CAS:528:DC%2BD2MXjs1Cmurw%3D
-
(2005)
Brain Res Brain Res Rev
, vol.48
, pp. 178-184
-
-
Owens, T.1
Babcock, A.A.2
Millward, J.M.3
Toft-Hansen, H.4
-
233
-
-
0032914896
-
A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease
-
10319892 10.1002/1531-8249(199905)45:5 <666::AID-ANA18>3.0.CO;2-3 1:STN:280:DyaK1M3ltFKisg%3D%3D
-
A Papassotiropoulos M Bagli F Jessen TA Bayer W Maier ML Rao R Heun 1999 A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease Ann Neurol 45 666 668 10319892 10.1002/1531-8249(199905)45:5<666::AID-ANA18>3.0.CO;2- 3 1:STN:280:DyaK1M3ltFKisg%3D%3D
-
(1999)
Ann Neurol
, vol.45
, pp. 666-668
-
-
Papassotiropoulos, A.1
Bagli, M.2
Jessen, F.3
Bayer, T.A.4
Maier, W.5
Rao, M.L.6
Heun, R.7
-
234
-
-
0030248270
-
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
-
8816718 10.1016/S0896-6273(00)80187-7 1:CAS:528:DyaK28XlvFans70%3D
-
DM Paresce RN Ghosh FR Maxfield 1996 Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor Neuron 17 553 565 8816718 10.1016/S0896-6273(00)80187-7 1:CAS:528:DyaK28XlvFans70%3D
-
(1996)
Neuron
, vol.17
, pp. 553-565
-
-
Paresce, D.M.1
Ghosh, R.N.2
Maxfield, F.R.3
-
235
-
-
0030175273
-
Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions
-
8980020 10.1006/nbdi.1996.0020 1:STN:280:DyaK2svlsVOlsQ%3D%3D
-
GM Pasinetti G Tocco S Sakhi WD Musleh MG DeSimoni P Mascarucci S Schreiber M Baudry CE Finch 1996 Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions Neurobiol Dis 3 197 204 8980020 10.1006/nbdi.1996.0020 1:STN:280:DyaK2svlsVOlsQ%3D%3D
-
(1996)
Neurobiol Dis
, vol.3
, pp. 197-204
-
-
Pasinetti, G.M.1
Tocco, G.2
Sakhi, S.3
Musleh, W.D.4
Desimoni, M.G.5
Mascarucci, P.6
Schreiber, S.7
Baudry, M.8
Finch, C.E.9
-
236
-
-
16644381634
-
Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance
-
15535425 1:CAS:528:DC%2BD2cXhtVSjs7rE
-
D Patsouris M Muller S Kersten 2004 Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance Curr Opin Investig Drugs 5 1045 1050 15535425 1:CAS:528:DC%2BD2cXhtVSjs7rE
-
(2004)
Curr Opin Investig Drugs
, vol.5
, pp. 1045-1050
-
-
Patsouris, D.1
Muller, M.2
Kersten, S.3
-
237
-
-
26044437911
-
The cholinergic anti-inflammatory pathway
-
15922555 10.1016/j.bbi.2005.03.015 1:CAS:528:DC%2BD2MXhtVymsrnO
-
VA Pavlov KJ Tracey 2005 The cholinergic anti-inflammatory pathway Brain Behav Immun 19 493 499 15922555 10.1016/j.bbi.2005.03.015 1:CAS:528: DC%2BD2MXhtVymsrnO
-
(2005)
Brain Behav Immun
, vol.19
, pp. 493-499
-
-
Pavlov, V.A.1
Tracey, K.J.2
-
238
-
-
0035826546
-
Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls
-
11378846 10.1002/ajmg.1371 1:STN:280:DC%2BD3M3pslSisg%3D%3D
-
RT Perry JS Collins LE Harrell RT Acton RC Go 2001 Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls Am J Med Genet 105 332 342 11378846 10.1002/ajmg.1371 1:STN:280:DC%2BD3M3pslSisg%3D%3D
-
(2001)
Am J Med Genet
, vol.105
, pp. 332-342
-
-
Perry, R.T.1
Collins, J.S.2
Harrell, L.E.3
Acton, R.T.4
Go, R.C.5
-
239
-
-
0035696345
-
The role of TNF and its receptors in Alzheimer's disease
-
11754994 10.1016/S0197-4580(01)00291-3 1:CAS:528:DC%2BD3MXptFylurc%3D
-
RT Perry JS Collins H Wiener R Acton RC Go 2001 The role of TNF and its receptors in Alzheimer's disease Neurobiol Aging 22 873 883 11754994 10.1016/S0197-4580(01)00291-3 1:CAS:528:DC%2BD3MXptFylurc%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 873-883
-
-
Perry, R.T.1
Collins, J.S.2
Wiener, H.3
Acton, R.4
Go, R.C.5
-
240
-
-
0028864801
-
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha
-
7479982 10.1073/pnas.92.24.11294 1:CAS:528:DyaK2MXps1altLg%3D
-
L Probert K Akassoglou M Pasparakis G Kontogeorgos G Kollias 1995 Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha Proc Natl Acad Sci USA 92 11294 11298 7479982 10.1073/pnas.92.24.11294 1:CAS:528:DyaK2MXps1altLg%3D
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11294-11298
-
-
Probert, L.1
Akassoglou, K.2
Pasparakis, M.3
Kontogeorgos, G.4
Kollias, G.5
-
241
-
-
0000398342
-
Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation
-
9830016 10.1074/jbc.273.49.32730 1:CAS:528:DyaK1cXnvFOnur4%3D
-
WQ Qiu DM Walsh Z Ye K Vekrellis J Zhang MB Podlisny MR Rosner A Safavi LB Hersh DJ Selkoe 1998 Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation J Biol Chem 273 32730 32738 9830016 10.1074/jbc.273.49.32730 1:CAS:528:DyaK1cXnvFOnur4%3D
-
(1998)
J Biol Chem
, vol.273
, pp. 32730-32738
-
-
Qiu, W.Q.1
Walsh, D.M.2
Ye, Z.3
Vekrellis, K.4
Zhang, J.5
Podlisny, M.B.6
Rosner, M.R.7
Safavi, A.8
Hersh, L.B.9
Selkoe, D.J.10
-
242
-
-
75449102536
-
Alzheimer's disease
-
20107219 10.1056/NEJMra0909142 1:CAS:528:DC%2BC3cXht1aqt7s%3D
-
HW Querfurth FM LaFerla 2010 Alzheimer's disease N Engl J Med 362 329 344 20107219 10.1056/NEJMra0909142 1:CAS:528:DC%2BC3cXht1aqt7s%3D
-
(2010)
N Engl J Med
, vol.362
, pp. 329-344
-
-
Querfurth, H.W.1
Laferla, F.M.2
-
243
-
-
0037728592
-
Different chromogranin immunoreactivity between prion and a-beta amyloid plaque
-
12692477 10.1097/00001756-200304150-00019 1:CAS:528:DC%2BD3sXivVCksrw%3D
-
CM Rangon S Haik BA Faucheux MH Metz-Boutigue F Fierville JP Fuchs JJ Hauw D Aunis 2003 Different chromogranin immunoreactivity between prion and a-beta amyloid plaque Neuroreport 14 755 758 12692477 10.1097/00001756- 200304150-00019 1:CAS:528:DC%2BD3sXivVCksrw%3D
-
(2003)
Neuroreport
, vol.14
, pp. 755-758
-
-
Rangon, C.M.1
Haik, S.2
Faucheux, B.A.3
Metz-Boutigue, M.H.4
Fierville, F.5
Fuchs, J.P.6
Hauw, J.J.7
Aunis, D.8
-
244
-
-
70449525704
-
Chemokines and chemokine receptors: Standing at the crossroads of immunobiology and neurobiology
-
19836265 10.1016/j.immuni.2009.09.010 1:CAS:528:DC%2BD1MXhsFylsbvF
-
RM Ransohoff 2009 Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology Immunity 31 711 721 19836265 10.1016/j.immuni.2009.09.010 1:CAS:528:DC%2BD1MXhsFylsbvF
-
(2009)
Immunity
, vol.31
, pp. 711-721
-
-
Ransohoff, R.M.1
-
245
-
-
0031791135
-
Binding of amyloid beta-protein to intracellular brain proteins in rat and human
-
9804283 10.1023/A:1020744216699 1:CAS:528:DyaK1cXmvVOrs78%3D
-
I Ray A Chauhan HM Wisniewski J Wegiel KS Kim VP Chauhan 1998 Binding of amyloid beta-protein to intracellular brain proteins in rat and human Neurochem Res 23 1277 1282 9804283 10.1023/A:1020744216699 1:CAS:528:DyaK1cXmvVOrs78%3D
-
(1998)
Neurochem Res
, vol.23
, pp. 1277-1282
-
-
Ray, I.1
Chauhan, A.2
Wisniewski, H.M.3
Wegiel, J.4
Kim, K.S.5
Chauhan, V.P.6
-
246
-
-
70349323417
-
CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation
-
19776284 10.1523/JNEUROSCI.3158-09.2009 1:CAS:528:DC%2BD1MXht1ertb3E
-
EG Reed-Geaghan JC Savage AG Hise GE Landreth 2009 CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation J Neurosci 29 11982 11992 19776284 10.1523/JNEUROSCI.3158-09.2009 1:CAS:528:DC%2BD1MXht1ertb3E
-
(2009)
J Neurosci
, vol.29
, pp. 11982-11992
-
-
Reed-Geaghan, E.G.1
Savage, J.C.2
Hise, A.G.3
Landreth, G.E.4
-
247
-
-
0345830739
-
Rofecoxib-no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study
-
14718699 1:CAS:528:DC%2BD3sXhtVWjtrrL
-
SA Reines GA Block JC Morris G Liu ML Nessly CR Lines BA Norman CC Baranak 2004 Rofecoxib-no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study Neurology 62 66 71 14718699 1:CAS:528: DC%2BD3sXhtVWjtrrL
-
(2004)
Neurology
, vol.62
, pp. 66-71
-
-
Reines, S.A.1
Block, G.A.2
Morris, J.C.3
Liu, G.4
Nessly, M.L.5
Lines, C.R.6
Norman, B.A.7
Baranak, C.C.8
-
249
-
-
45949106077
-
Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
-
18509040 10.1523/JNEUROSCI.1146-08.2008 1:CAS:528:DC%2BD1cXmvFWmsb8%3D
-
KL Richard M Filali P Prefontaine S Rivest 2008 Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease J Neurosci 28 5784 5793 18509040 10.1523/JNEUROSCI.1146-08.2008 1:CAS:528:DC%2BD1cXmvFWmsb8%3D
-
(2008)
J Neurosci
, vol.28
, pp. 5784-5793
-
-
Richard, K.L.1
Filali, M.2
Prefontaine, P.3
Rivest, S.4
-
250
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
9422508 10.1038/34178 1:CAS:528:DyaK1cXktVShtQ%3D%3D
-
M Ricote AC Li TM Willson CJ Kelly CK Glass 1998 The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 391 79 82 9422508 10.1038/34178 1:CAS:528:DyaK1cXktVShtQ%3D%3D
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
251
-
-
3543067962
-
Neurodegenerative disorders associated with diabetes mellitus
-
15175861 10.1007/s00109-004-0552-1
-
M Ristow 2004 Neurodegenerative disorders associated with diabetes mellitus J Mol Med 82 510 529 15175861 10.1007/s00109-004-0552-1
-
(2004)
J Mol Med
, vol.82
, pp. 510-529
-
-
Ristow, M.1
-
252
-
-
60849109489
-
Astroglia in dementia and Alzheimer's disease
-
10.1038/cdd.2008.172 1:CAS:528:DC%2BD1MXit1Wkur8%3D
-
JJ Rodriguez M Olabarria A Chvatal A Verkhratsky 2009 Astroglia in dementia and Alzheimer's disease Cell Death Diff 16 378 385 10.1038/cdd.2008.172 1:CAS:528:DC%2BD1MXit1Wkur8%3D
-
(2009)
Cell Death Diff
, vol.16
, pp. 378-385
-
-
Rodriguez, J.J.1
Olabarria, M.2
Chvatal, A.3
Verkhratsky, A.4
-
253
-
-
0026447529
-
Complement activation by beta-amyloid in Alzheimer-disease
-
1438191 10.1073/pnas.89.21.10016 1:CAS:528:DyaK3sXitVektg%3D%3D
-
J Rogers NR Cooper S Webster J Schultz PL McGeer SD Styren WH Civin L Brachova B Bradt P Ward I Lieberburg 1992 Complement activation by beta-amyloid in Alzheimer-disease Proc Natl Acad Sci USA 89 10016 10020 1438191 10.1073/pnas.89.21.10016 1:CAS:528:DyaK3sXitVektg%3D%3D
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10016-10020
-
-
Rogers, J.1
Cooper, N.R.2
Webster, S.3
Schultz, J.4
McGeer, P.L.5
Styren, S.D.6
Civin, W.H.7
Brachova, L.8
Bradt, B.9
Ward, P.10
Lieberburg, I.11
-
254
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
8351023 1:STN:280:DyaK3szlsVGrtw%3D%3D
-
J Rogers LC Kirby SR Hempelman DL Berry PL McGeer AW Kaszniak J Zalinski M Cofield L Mansukhani P Willson 1993 Clinical trial of indomethacin in Alzheimer's disease Neurology 43 1609 1611 8351023 1:STN:280: DyaK3szlsVGrtw%3D%3D
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
Berry, D.L.4
McGeer, P.L.5
Kaszniak, A.W.6
Zalinski, J.7
Cofield, M.8
Mansukhani, L.9
Willson, P.10
-
255
-
-
0033525735
-
Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-untranslated region sequences
-
10037734 10.1074/jbc.274.10.6421 1:CAS:528:DyaK1MXhs1Cjsrs%3D
-
JT Rogers LM Leiter J McPhee CM Cahill SS Zhan H Potter LN Nilsson 1999 Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-untranslated region sequences J Biol Chem 274 6421 6431 10037734 10.1074/jbc.274.10.6421 1:CAS:528:DyaK1MXhs1Cjsrs%3D
-
(1999)
J Biol Chem
, vol.274
, pp. 6421-6431
-
-
Rogers, J.T.1
Leiter, L.M.2
McPhee, J.3
Cahill, C.M.4
Zhan, S.S.5
Potter, H.6
Nilsson, L.N.7
-
256
-
-
0030583248
-
Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes
-
8753786 10.1006/bbrc.1996.1197 1:CAS:528:DyaK28XltVelsLo%3D
-
F Rossi E Bianchini 1996 Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes Biochem Biophys Res Commun 225 474 478 8753786 10.1006/bbrc.1996.1197 1:CAS:528:DyaK28XltVelsLo%3D
-
(1996)
Biochem Biophys Res Commun
, vol.225
, pp. 474-478
-
-
Rossi, F.1
Bianchini, E.2
-
257
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of i kappa B kinase
-
10638762 10.1038/47520 1:CAS:528:DC%2BD3cXlvVWjsw%3D%3D
-
A Rossi P Kapahi G Natoli T Takahashi Y Chen M Karin MG Santoro 2000 Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of I kappa B kinase Nature 403 103 108 10638762 10.1038/47520 1:CAS:528: DC%2BD3cXlvVWjsw%3D%3D
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
Takahashi, T.4
Chen, Y.5
Karin, M.6
Santoro, M.G.7
-
258
-
-
13244264935
-
Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme
-
15663471 10.1111/j.1471-4159.2004.02857.x 1:CAS:528: DC%2BD2MXptFamtw%3D%3D
-
S Rossner C Lange-Dohna U Zeitschel JR Perez-Polo 2005 Alzheimer's disease beta-secretase BACE1 is not a neuron-specific enzyme J Neurochem 92 226 234 15663471 10.1111/j.1471-4159.2004.02857.x 1:CAS:528:DC%2BD2MXptFamtw%3D%3D
-
(2005)
J Neurochem
, vol.92
, pp. 226-234
-
-
Rossner, S.1
Lange-Dohna, C.2
Zeitschel, U.3
Perez-Polo, J.R.4
-
259
-
-
33745252827
-
Increased intrathecal TGF-beta 1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients
-
16688597 10.1007/s10072-006-0562-6 1:STN:280:DC%2BD283mtlKqsA%3D%3D
-
E Rota G Bellone P Rocca B Bergamasco G Emanuelli P Ferrero 2006 Increased intrathecal TGF-beta 1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients Neurol Sci 27 33 39 16688597 10.1007/s10072-006- 0562-6 1:STN:280:DC%2BD283mtlKqsA%3D%3D
-
(2006)
Neurol Sci
, vol.27
, pp. 33-39
-
-
Rota, E.1
Bellone, G.2
Rocca, P.3
Bergamasco, B.4
Emanuelli, G.5
Ferrero, P.6
-
260
-
-
0024428072
-
A4-protein in Alzheimers-disease-primary and secondary cellular events in extracellular amyloid deposition
-
2677252 10.1097/00005072-198911000-00009 1:STN:280:DyaK3c%2FhtFWksw%3D%3D
-
JM Rozemuller P Eikelenboom FC Stam K Beyreuther CL Masters 1989 A4-protein in Alzheimers-disease-primary and secondary cellular events in extracellular amyloid deposition J Neuropath Exp Neurol 48 674 691 2677252 10.1097/00005072-198911000-00009 1:STN:280:DyaK3c%2FhtFWksw%3D%3D
-
(1989)
J Neuropath Exp Neurol
, vol.48
, pp. 674-691
-
-
Rozemuller, J.M.1
Eikelenboom, P.2
Stam, F.C.3
Beyreuther, K.4
Masters, C.L.5
-
261
-
-
64249169414
-
Activation of Microglia by Amyloid beta Requires P2X(7) Receptor Expression
-
19299738 10.4049/jimmunol.0803612 1:CAS:528:DC%2BD1MXjsVSju70%3D
-
JM Sanz P Chiozzi D Ferrari M Colaianna M Idzko S Falzoni R Fellin L Trabace F Di Virgilio 2009 Activation of Microglia by Amyloid beta Requires P2X(7) Receptor Expression J Immunol 182 4378 4385 19299738 10.4049/jimmunol. 0803612 1:CAS:528:DC%2BD1MXjsVSju70%3D
-
(2009)
J Immunol
, vol.182
, pp. 4378-4385
-
-
Sanz, J.M.1
Chiozzi, P.2
Ferrari, D.3
Colaianna, M.4
Idzko, M.5
Falzoni, S.6
Fellin, R.7
Trabace, L.8
Di Virgilio, F.9
-
262
-
-
0242609178
-
Nonsteroidal anti-inflammatory drugs and peroxisome proliferator- activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
-
14586007 1:CAS:528:DC%2BD3sXovVKis7w%3D
-
M Sastre I Dewachter GE Landreth TM Willson T Klockgether F Van Leuven MT Heneka 2003 Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase J Neurosci 23 9796 9804 14586007 1:CAS:528:DC%2BD3sXovVKis7w%3D
-
(2003)
J Neurosci
, vol.23
, pp. 9796-9804
-
-
Sastre, M.1
Dewachter, I.2
Landreth, G.E.3
Willson, T.M.4
Klockgether, T.5
Van Leuven, F.6
Heneka, M.T.7
-
263
-
-
31044445398
-
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPAR gamma
-
16407166 10.1073/pnas.0503839103 1:CAS:528:DC%2BD28XpsVSluw%3D%3D
-
M Sastre I Dewachter S Rossner N Bogdanovic E Rosen P Borghgraef BO Evert L Dumitrescu-Ozimek DR Thal G Landreth J Walter T Klockgether F Van Leuven MT Heneka 2006 Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPAR gamma Proc Natl Acad Sci USA 103 443 448 16407166 10.1073/pnas.0503839103 1:CAS:528:DC%2BD28XpsVSluw%3D%3D
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 443-448
-
-
Sastre, M.1
Dewachter, I.2
Rossner, S.3
Bogdanovic, N.4
Rosen, E.5
Borghgraef, P.6
Evert, B.O.7
Dumitrescu-Ozimek, L.8
Thal, D.R.9
Landreth, G.10
Walter, J.11
Klockgether, T.12
Van Leuven, F.13
Heneka, M.T.14
-
264
-
-
60849137841
-
Induction of toll-like receptor 9 signaling as a method for ameliorating Alzheimer's disease-related pathology
-
19211891 10.1523/JNEUROSCI.5715-08.2009 1:CAS:528:DC%2BD1MXit1Wiur8%3D
-
H Scholtzova RJ Kascsak KA Bates A Boutajangout DJ Kerr HC Meeker PD Mehta DS Spinner T Wisniewski 2009 Induction of toll-like receptor 9 signaling as a method for ameliorating Alzheimer's disease-related pathology J Neurosci 29 1846 1854 19211891 10.1523/JNEUROSCI.5715-08.2009 1:CAS:528: DC%2BD1MXit1Wiur8%3D
-
(2009)
J Neurosci
, vol.29
, pp. 1846-1854
-
-
Scholtzova, H.1
Kascsak, R.J.2
Bates, K.A.3
Boutajangout, A.4
Kerr, D.J.5
Meeker, H.C.6
Mehta, P.D.7
Spinner, D.S.8
Wisniewski, T.9
-
265
-
-
0034114456
-
Cascading glia reactions: A common pathomechanism and its differentiated control by cyclic nucleotide signaling
-
Schubert P, Morino T, Miyazaki H, Ogata T, Nakamura Y, Marchini C, Ferroni S (2000) Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling. Ann N Y Acad Sci 903:24-33
-
(2000)
Ann N y Acad Sci
, vol.903
, pp. 24-33
-
-
Schubert, P.1
Morino, T.2
Miyazaki, H.3
Ogata, T.4
Nakamura, Y.5
Marchini, C.6
Ferroni, S.7
-
266
-
-
23944490153
-
The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice
-
16120782 10.1523/JNEUROSCI.2038-05.2005 1:CAS:528:DC%2BD2MXpvVKgu7k%3D
-
B Schutz J Reimann L Dumitrescu-Ozimek K Kappes-Horn GE Landreth B Schurmann A Zimmer MT Heneka 2005 The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice J Neurosci 25 7805 7812 16120782 10.1523/JNEUROSCI.2038-05.2005 1:CAS:528:DC%2BD2MXpvVKgu7k%3D
-
(2005)
J Neurosci
, vol.25
, pp. 7805-7812
-
-
Schutz, B.1
Reimann, J.2
Dumitrescu-Ozimek, L.3
Kappes-Horn, K.4
Landreth, G.E.5
Schurmann, B.6
Zimmer, A.7
Heneka, M.T.8
-
267
-
-
13444293174
-
Defining molecular targets to prevent Alzheimer disease
-
15710846 10.1001/archneur.62.2.192
-
DJ Selkoe 2005 Defining molecular targets to prevent Alzheimer disease Arch Neurol 62 192 195 15710846 10.1001/archneur.62.2.192
-
(2005)
Arch Neurol
, vol.62
, pp. 192-195
-
-
Selkoe, D.J.1
-
268
-
-
0025092159
-
Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor
-
2104886 1:CAS:528:DyaK3cXps1KrsQ%3D%3D
-
KW Selmaj M Farooq WT Norton CS Raine CF Brosnan 1990 Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor J Immunol 144 129 135 2104886 1:CAS:528:DyaK3cXps1KrsQ%3D%3D
-
(1990)
J Immunol
, vol.144
, pp. 129-135
-
-
Selmaj, K.W.1
Farooq, M.2
Norton, W.T.3
Raine, C.S.4
Brosnan, C.F.5
-
269
-
-
25144435958
-
Systemic inflammation induces apoptosis with variable vulnerability of different brain regions
-
16122904 10.1016/j.jchemneu.2005.07.003 1:CAS:528:DC%2BD2MXhtVegurnJ
-
A Semmler T Okulla M Sastre L Dumitrescu-Ozimek MT Heneka 2005 Systemic inflammation induces apoptosis with variable vulnerability of different brain regions J Chem Neuroanat 30 144 157 16122904 10.1016/j.jchemneu.2005.07.003 1:CAS:528:DC%2BD2MXhtVegurnJ
-
(2005)
J Chem Neuroanat
, vol.30
, pp. 144-157
-
-
Semmler, A.1
Okulla, T.2
Sastre, M.3
Dumitrescu-Ozimek, L.4
Heneka, M.T.5
-
270
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
1406936 10.1038/359325a0 1:CAS:528:DyaK38XmtFSisrc%3D
-
P Seubert C Vigo-Pelfrey F Esch M Lee H Dovey D Davis S Sinha M Schlossmacher J Whaley C Swindlehurst 1992 Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids Nature 359 325 327 1406936 10.1038/359325a0 1:CAS:528:DyaK38XmtFSisrc%3D
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
-
271
-
-
34249899174
-
Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
-
17549256 10.1172/JCI31450 1:CAS:528:DC%2BD2sXmsVWkurg%3D
-
SS Shaftel S Kyrkanides JA Olschowka JN Miller RE Johnson MK O'Banion 2007 Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology J Clin Invest 117 1595 1604 17549256 10.1172/JCI31450 1:CAS:528:DC%2BD2sXmsVWkurg%3D
-
(2007)
J Clin Invest
, vol.117
, pp. 1595-1604
-
-
Shaftel, S.S.1
Kyrkanides, S.2
Olschowka, J.A.3
Miller, J.N.4
Johnson, R.E.5
O'Banion, M.K.6
-
272
-
-
0141991166
-
Yin and Yang: Complement activation and regulation in Alzheimer's disease
-
14568360 1:CAS:528:DC%2BD3sXotVCjsr4%3D
-
Y Shen S Meri 2003 Yin and Yang: complement activation and regulation in Alzheimer's disease Prog Neurobiol 70 463 472 14568360 1:CAS:528: DC%2BD3sXotVCjsr4%3D
-
(2003)
Prog Neurobiol
, vol.70
, pp. 463-472
-
-
Shen, Y.1
Meri, S.2
-
273
-
-
0034042595
-
Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo
-
10.1006/exnr.2000.7393 1:CAS:528:DC%2BD3cXjs12gsL4%3D
-
JG Sheng SG Zhu RA Jones WST Griffin RE Mrak 2000 Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo Ex Neurol 163 388 391 10.1006/exnr.2000.7393 1:CAS:528:DC%2BD3cXjs12gsL4%3D
-
(2000)
Ex Neurol
, vol.163
, pp. 388-391
-
-
Sheng, J.G.1
Zhu, S.G.2
Jones, R.A.3
Griffin, W.S.T.4
Mrak, R.E.5
-
274
-
-
0042835437
-
Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice
-
13678674 10.1016/S0969-9961(03)00069-X 1:CAS:528:DC%2BD3sXnt1amtL8%3D
-
JG Sheng SH Bora G Xu DR Borchelt DL Price VE Koliatsos 2003 Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice Neurobiol Dis 14 133 145 13678674 10.1016/S0969-9961(03)00069-X 1:CAS:528:DC%2BD3sXnt1amtL8%3D
-
(2003)
Neurobiol Dis
, vol.14
, pp. 133-145
-
-
Sheng, J.G.1
Bora, S.H.2
Xu, G.3
Borchelt, D.R.4
Price, D.L.5
Koliatsos, V.E.6
-
275
-
-
17144380506
-
Microglia lacking e Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity
-
15793296 1:CAS:528:DC%2BD2MXjsFaksLc%3D
-
FS Shie RM Breyer TJ Montine 2005 Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity Am J Pathol 166 1163 1172 15793296 1:CAS:528:DC%2BD2MXjsFaksLc%3D
-
(2005)
Am J Pathol
, vol.166
, pp. 1163-1172
-
-
Shie, F.S.1
Breyer, R.M.2
Montine, T.J.3
-
276
-
-
27444436866
-
Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity
-
15920732 10.1002/glia.20220
-
FS Shie KS Montine RM Breyer TJ Montine 2005 Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity Glia 52 70 77 15920732 10.1002/glia.20220
-
(2005)
Glia
, vol.52
, pp. 70-77
-
-
Shie, F.S.1
Montine, K.S.2
Breyer, R.M.3
Montine, T.J.4
-
277
-
-
58749093072
-
IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia
-
18941241 1:CAS:528:DC%2BD1cXht1Krt77N
-
E Shimizu K Kawahara M Kajizono M Sawada H Nakayama 2008 IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia J Immunol 181 6503 6513 18941241 1:CAS:528:DC%2BD1cXht1Krt77N
-
(2008)
J Immunol
, vol.181
, pp. 6503-6513
-
-
Shimizu, E.1
Kawahara, K.2
Kajizono, M.3
Sawada, M.4
Nakayama, H.5
-
278
-
-
0026760261
-
Production of the Alzheimer amyloid beta protein by normal proteolytic processing
-
1439760 10.1126/science.1439760 1:CAS:528:DyaK38XmtlSrs70%3D
-
M Shoji TE Golde J Ghiso TT Cheung S Estus LM Shaffer XD Cai DM McKay R Tintner B Frangione 1992 Production of the Alzheimer amyloid beta protein by normal proteolytic processing Science 258 126 129 1439760 10.1126/science. 1439760 1:CAS:528:DyaK38XmtlSrs70%3D
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.E.2
Ghiso, J.3
Cheung, T.T.4
Estus, S.5
Shaffer, L.M.6
Cai, X.D.7
McKay, D.M.8
Tintner, R.9
Frangione, B.10
-
279
-
-
6944234040
-
Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia
-
15084516 1:CAS:528:DC%2BD2cXkslWit7g%3D
-
AR Simard S Rivest 2004 Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia FASEB J 18 998 1000 15084516 1:CAS:528:DC%2BD2cXkslWit7g%3D
-
(2004)
FASEB J
, vol.18
, pp. 998-1000
-
-
Simard, A.R.1
Rivest, S.2
-
280
-
-
37049028157
-
Neuroprotective effects of resident microglia following acute brain injury
-
17722035 10.1002/cne.21469 1:CAS:528:DC%2BD2sXhtFKju7%2FE
-
AR Simard S Rivest 2007 Neuroprotective effects of resident microglia following acute brain injury J Comp Neurol 504 716 729 17722035 10.1002/cne.21469 1:CAS:528:DC%2BD2sXhtFKju7%2FE
-
(2007)
J Comp Neurol
, vol.504
, pp. 716-729
-
-
Simard, A.R.1
Rivest, S.2
-
281
-
-
32344440522
-
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
-
16476660 10.1016/j.neuron.2006.01.022 1:CAS:528:DC%2BD28XhvFyjsbs%3D
-
AR Simard D Soulet G Gowing JP Julien S Rivest 2006 Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease Neuron 49 489 502 16476660 10.1016/j.neuron.2006.01.022 1:CAS:528:DC%2BD28XhvFyjsbs%3D
-
(2006)
Neuron
, vol.49
, pp. 489-502
-
-
Simard, A.R.1
Soulet, D.2
Gowing, G.3
Julien, J.P.4
Rivest, S.5
-
282
-
-
0026774797
-
Induction of nitric oxide synthase in glial cells
-
1379633 10.1111/j.1471-4159.1992.tb08328.x 1:CAS:528:DyaK38XlsVyju7w%3D
-
ML Simmons S Murphy 1992 Induction of nitric oxide synthase in glial cells J Neurochem 59 897 905 1379633 10.1111/j.1471-4159.1992.tb08328.x 1:CAS:528:DyaK38XlsVyju7w%3D
-
(1992)
J Neurochem
, vol.59
, pp. 897-905
-
-
Simmons, M.L.1
Murphy, S.2
-
283
-
-
0028896346
-
Inflammatory mediator stimulation of astrocytes and meningeal fibroblasts induces neuronal degeneration via the nitridergic pathway
-
7798922 10.1046/j.1471-4159.1995.64010266.x 1:CAS:528:DyaK2MXislSjsbk%3D
-
SD Skaper L Facci A Leon 1995 Inflammatory mediator stimulation of astrocytes and meningeal fibroblasts induces neuronal degeneration via the nitridergic pathway J Neurochem 64 266 276 7798922 10.1046/j.1471-4159.1995. 64010266.x 1:CAS:528:DyaK2MXislSjsbk%3D
-
(1995)
J Neurochem
, vol.64
, pp. 266-276
-
-
Skaper, S.D.1
Facci, L.2
Leon, A.3
-
284
-
-
4444274138
-
Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum
-
15234107 10.1016/j.neuint.2004.04.007 1:CAS:528:DC%2BD2cXmtlChtrY%3D
-
H Slawik B Volk B Fiebich M Hull 2004 Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum Neurochem Int 45 653 660 15234107 10.1016/j.neuint.2004.04.007 1:CAS:528: DC%2BD2cXmtlChtrY%3D
-
(2004)
Neurochem Int
, vol.45
, pp. 653-660
-
-
Slawik, H.1
Volk, B.2
Fiebich, B.3
Hull, M.4
-
285
-
-
0035704245
-
Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease
-
11786245 10.1016/S0361-9230(01)00730-4 1:CAS:528:DC%2BD38XitlWltA%3D%3D
-
LM Sly RF Krzesicki JR Brashler AE Buhl DD McKinley DB Carter JE Chin 2001 Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease Brain Res Bull 56 581 588 11786245 10.1016/S0361-9230(01) 00730-4 1:CAS:528:DC%2BD38XitlWltA%3D%3D
-
(2001)
Brain Res Bull
, vol.56
, pp. 581-588
-
-
Sly, L.M.1
Krzesicki, R.F.2
Brashler, J.R.3
Buhl, A.E.4
McKinley, D.D.5
Carter, D.B.6
Chin, J.E.7
-
286
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
9092586 1:CAS:528:DyaK2sXisValtL4%3D
-
MA Smith PL Richey Harris LM Sayre JS Beckman G Perry 1997 Widespread peroxynitrite-mediated damage in Alzheimer's disease J Neurosci 17 2653 2657 9092586 1:CAS:528:DyaK2sXisValtL4%3D
-
(1997)
J Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
287
-
-
0028168596
-
Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury
-
10.1046/j.1471-4159.1994.63020781.x 1:CAS:528:DyaK2cXltVGqsbg%3D
-
VL Smithswintosky LC Pettigrew SD Craddock AR Culwell RE Rydel MP Mattson 1994 Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury J Neurochem 63 781 784 10.1046/j.1471-4159.1994.63020781.x 1:CAS:528:DyaK2cXltVGqsbg%3D
-
(1994)
J Neurochem
, vol.63
, pp. 781-784
-
-
Smithswintosky, V.L.1
Pettigrew, L.C.2
Craddock, S.D.3
Culwell, A.R.4
Rydel, R.E.5
Mattson, M.P.6
-
288
-
-
0036277146
-
Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes
-
12044988 10.1016/S0165-5728(02)00112-1 1:CAS:528:DC%2BD38XktFKis7g%3D
-
HA Smits A Rijsmus JH van Loon JWY Wat J Verhoef LA Boven HSLM Nottet 2002 Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes J Neuroimmunol 127 160 168 12044988 10.1016/S0165-5728(02)00112-1 1:CAS:528:DC%2BD38XktFKis7g%3D
-
(2002)
J Neuroimmunol
, vol.127
, pp. 160-168
-
-
Smits, H.A.1
Rijsmus, A.2
Van Loon, J.H.3
Wat, J.W.Y.4
Verhoef, J.5
Boven, L.A.6
Nottet, H.S.L.M.7
-
289
-
-
0027966134
-
Complement C1Q does not bind monomeric beta-amyloid
-
8070518 10.1006/exnr.1994.1121 1:CAS:528:DyaK2MXhsl2jsLw%3D
-
SW Snyder GT Wang L Barrett US Ladror D Casuto CM Lee GA Krafft RB Holzman TF Holzman 1994 Complement C1Q does not bind monomeric beta-amyloid Exp Neurol 128 136 142 8070518 10.1006/exnr.1994.1121 1:CAS:528:DyaK2MXhsl2jsLw%3D
-
(1994)
Exp Neurol
, vol.128
, pp. 136-142
-
-
Snyder, S.W.1
Wang, G.T.2
Barrett, L.3
Ladror, U.S.4
Casuto, D.5
Lee, C.M.6
Krafft, G.A.7
Holzman, R.B.8
Holzman, T.F.9
-
290
-
-
0031656782
-
Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor
-
9736027 1:CAS:528:DyaK1cXmtFKnu78%3D
-
AK Stalder MJ Carson A Pagenstecher VC Asensio C Kincaid M Benedict HC Powell E Masliah IL Campbell 1998 Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor Am J Pathol 153 767 783 9736027 1:CAS:528:DyaK1cXmtFKnu78%3D
-
(1998)
Am J Pathol
, vol.153
, pp. 767-783
-
-
Stalder, A.K.1
Carson, M.J.2
Pagenstecher, A.3
Asensio, V.C.4
Kincaid, C.5
Benedict, M.6
Powell, H.C.7
Masliah, E.8
Campbell, I.L.9
-
291
-
-
30644479563
-
Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice
-
16319312 10.1523/JNEUROSCI.2545-05.2005 1:CAS:528:DC%2BD2MXhtlWlt7vJ
-
AK Stalder F Ermini L Bondolfi W Krenger GJ Burbach T Deller J Coomaraswamy M Staufenbiel R Landmann M Jucker 2005 Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice J Neurosci 25 11125 11132 16319312 10.1523/JNEUROSCI.2545-05.2005 1:CAS:528:DC%2BD2MXhtlWlt7vJ
-
(2005)
J Neurosci
, vol.25
, pp. 11125-11132
-
-
Stalder, A.K.1
Ermini, F.2
Bondolfi, L.3
Krenger, W.4
Burbach, G.J.5
Deller, T.6
Coomaraswamy, J.7
Staufenbiel, M.8
Landmann, R.9
Jucker, M.10
-
292
-
-
36849076770
-
The classical complement cascade mediates CNS synapse elimination
-
18083105 10.1016/j.cell.2007.10.036 1:CAS:528:DC%2BD1cXksFGnsw%3D%3D
-
B Stevens NJ Allen LE Vazquez GR Howell KS Christopherson N Nouri KD Micheva AK Mehalow AD Huberman B Stafford A Sher AM Litke JD Lambris SJ Smith SWM John BA Barres 2007 The classical complement cascade mediates CNS synapse elimination Cell 131 1164 1178 18083105 10.1016/j.cell.2007.10.036 1:CAS:528:DC%2BD1cXksFGnsw%3D%3D
-
(2007)
Cell
, vol.131
, pp. 1164-1178
-
-
Stevens, B.1
Allen, N.J.2
Vazquez, L.E.3
Howell, G.R.4
Christopherson, K.S.5
Nouri, N.6
Micheva, K.D.7
Mehalow, A.K.8
Huberman, A.D.9
Stafford, B.10
Sher, A.11
Litke, A.M.12
Lambris, J.D.13
Smith, S.J.14
John, S.W.M.15
Barres, B.A.16
-
293
-
-
0030897133
-
Risk of Alzheimer's disease and duration of NSAID use
-
9065537 1:STN:280:DyaK2s3hslyktA%3D%3D
-
WF Stewart C Kawas M Corrada EJ Metter 1997 Risk of Alzheimer's disease and duration of NSAID use Neurology 48 626 632 9065537 1:STN:280: DyaK2s3hslyktA%3D%3D
-
(1997)
Neurology
, vol.48
, pp. 626-632
-
-
Stewart, W.F.1
Kawas, C.2
Corrada, M.3
Metter, E.J.4
-
294
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
20037584 10.1038/ni.1836 1:CAS:528:DC%2BD1MXhs1SktbvE
-
CR Stewart LM Stuart K Wilkinson JM van Gils J Deng A Halle KJ Rayner L Boyer R Zhong WA Frazier A Lacy-Hulbert JE Khoury DT Golenbock KJ Moore 2010 CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer Nat Immunol 11 155 161 20037584 10.1038/ni.1836 1:CAS:528:DC%2BD1MXhs1SktbvE
-
(2010)
Nat Immunol
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
Van Gils, J.M.4
Deng, J.5
Halle, A.6
Rayner, K.J.7
Boyer, L.8
Zhong, R.9
Frazier, W.A.10
Lacy-Hulbert, A.11
Khoury, J.E.12
Golenbock, D.T.13
Moore, K.J.14
-
295
-
-
20244390429
-
The functional role of the ELR motif in CXC chemokine-mediated angiogenesis
-
7592998 10.1074/jbc.270.45.27348 1:CAS:528:DyaK2MXpsVGltbc%3D
-
RM Strieter PJ Polverini SL Kunkel DA Arenberg MD Burdick J Kasper J Dzuiba J Van Damme A Walz D Marriott 1995 The functional role of the ELR motif in CXC chemokine-mediated angiogenesis J Biol Chem 270 27348 27357 7592998 10.1074/jbc.270.45.27348 1:CAS:528:DyaK2MXpsVGltbc%3D
-
(1995)
J Biol Chem
, vol.270
, pp. 27348-27357
-
-
Strieter, R.M.1
Polverini, P.J.2
Kunkel, S.L.3
Arenberg, D.A.4
Burdick, M.D.5
Kasper, J.6
Dzuiba, J.7
Van Damme, J.8
Walz, A.9
Marriott, D.10
-
296
-
-
0001509578
-
Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide
-
3906650 10.1073/pnas.82.22.7738 1:CAS:528:DyaL28XksFOi
-
DJ Stuehr MA Marletta 1985 Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide Proc Natl Acad Sci USA 82 7738 7742 3906650 10.1073/pnas.82.22.7738 1:CAS:528:DyaL28XksFOi
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 7738-7742
-
-
Stuehr, D.J.1
Marletta, M.A.2
-
297
-
-
9644275598
-
Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease
-
15579461 1:CAS:528:DC%2BD2MXhs1Kmtw%3D%3D
-
S Sung H Yang K Uryu EB Lee L Zhao D Shineman JQ Trojanowski VM Lee D Pratico 2004 Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease Am J Pathol 165 2197 2206 15579461 1:CAS:528: DC%2BD2MXhs1Kmtw%3D%3D
-
(2004)
Am J Pathol
, vol.165
, pp. 2197-2206
-
-
Sung, S.1
Yang, H.2
Uryu, K.3
Lee, E.B.4
Zhao, L.5
Shineman, D.6
Trojanowski, J.Q.7
Lee, V.M.8
Pratico, D.9
-
298
-
-
0033525574
-
Cerebral neurons express interleukin-6 after transient forebrain ischemia in gerbils
-
10203245 10.1016/S0304-3940(99)00051-8 1:CAS:528:DyaK1MXhs1Onur0%3D
-
S Suzuki K Tanaka E Nagata D Ito T Dembo Y Fukuuchi 1999 Cerebral neurons express interleukin-6 after transient forebrain ischemia in gerbils Neurosci Lett 262 117 120 10203245 10.1016/S0304-3940(99)00051-8 1:CAS:528: DyaK1MXhs1Onur0%3D
-
(1999)
Neurosci Lett
, vol.262
, pp. 117-120
-
-
Suzuki, S.1
Tanaka, K.2
Nagata, E.3
Ito, D.4
Dembo, T.5
Fukuuchi, Y.6
-
299
-
-
0035255055
-
IL-4, IL-10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
-
11137576 10.1016/S0165-5728(00)00404-5 1:CAS:528:DC%2BD3MXhsVSrtr0%3D
-
AM Szczepanik S Funes W Petko GE Ringheim 2001 IL-4, IL-10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line J Neuroimmunol 113 49 62 11137576 10.1016/S0165-5728(00)00404-5 1:CAS:528:DC%2BD3MXhsVSrtr0%3D
-
(2001)
J Neuroimmunol
, vol.113
, pp. 49-62
-
-
Szczepanik, A.M.1
Funes, S.2
Petko, W.3
Ringheim, G.E.4
-
300
-
-
0035085610
-
Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo
-
11279286 10.1046/j.1471-4159.2001.t01-1-00240.x 1:CAS:528: DC%2BD3MXis1Kltbg%3D
-
AM Szczepanik D Rampe GE Ringheim 2001 Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo J Neurochem 77 304 317 11279286 10.1046/j.1471-4159.2001.t01-1-00240.x 1:CAS:528:DC%2BD3MXis1Kltbg%3D
-
(2001)
J Neurochem
, vol.77
, pp. 304-317
-
-
Szczepanik, A.M.1
Rampe, D.2
Ringheim, G.E.3
-
302
-
-
3042601107
-
Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons
-
15234114 10.1016/j.neuint.2004.02.005 1:CAS:528:DC%2BD2cXlsVart7g%3D
-
T Takadera Y Shiraishi T Ohyashiki 2004 Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons Neurochem Int 45 713 719 15234114 10.1016/j.neuint.2004.02.005 1:CAS:528:DC%2BD2cXlsVart7g%3D
-
(2004)
Neurochem Int
, vol.45
, pp. 713-719
-
-
Takadera, T.1
Shiraishi, Y.2
Ohyashiki, T.3
-
303
-
-
0036403838
-
Oxidative stress increases expression and activity of BACE in NT2 neurons
-
12270690 10.1006/nbdi.2002.0515 1:CAS:528:DC%2BD38XmvFais7Y%3D
-
E Tamagno P Bardini A Obbili A Vitali R Borghi D Zaccheo MA Pronzato O Danni MA Smith G Perry M Tabaton 2002 Oxidative stress increases expression and activity of BACE in NT2 neurons Neurobiol Dis 10 279 288 12270690 10.1006/nbdi.2002.0515 1:CAS:528:DC%2BD38XmvFais7Y%3D
-
(2002)
Neurobiol Dis
, vol.10
, pp. 279-288
-
-
Tamagno, E.1
Bardini, P.2
Obbili, A.3
Vitali, A.4
Borghi, R.5
Zaccheo, D.6
Pronzato, M.A.7
Danni, O.8
Smith, M.A.9
Perry, G.10
Tabaton, M.11
-
304
-
-
0033579382
-
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation
-
10600748 10.1126/science.286.5448.2352 1:CAS:528:DC%2BD3cXjvVSl
-
J Tan T Town D Paris T Mori Z Suo F Crawford MP Mattson RA Flavell M Mullan 1999 Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation Science 286 2352 2355 10600748 10.1126/science.286. 5448.2352 1:CAS:528:DC%2BD3cXjvVSl
-
(1999)
Science
, vol.286
, pp. 2352-2355
-
-
Tan, J.1
Town, T.2
Paris, D.3
Mori, T.4
Suo, Z.5
Crawford, F.6
Mattson, M.P.7
Flavell, R.A.8
Mullan, M.9
-
305
-
-
0026442657
-
Tumor necrosis factor alters synaptic transmission in rat hippocampal slices
-
1337194 10.1016/0304-3940(92)90071-E 1:CAS:528:DyaK3sXhtVSjtb8%3D
-
V Tancredi G D'Arcangelo F Grassi P Tarroni G Palmieri A Santoni F Eusebi 1992 Tumor necrosis factor alters synaptic transmission in rat hippocampal slices Neurosci Lett 146 176 178 1337194 10.1016/0304-3940(92)90071-E 1:CAS:528:DyaK3sXhtVSjtb8%3D
-
(1992)
Neurosci Lett
, vol.146
, pp. 176-178
-
-
Tancredi, V.1
D'Arcangelo, G.2
Grassi, F.3
Tarroni, P.4
Palmieri, G.5
Santoni, A.6
Eusebi, F.7
-
306
-
-
0033943842
-
The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK
-
10899938 10.1046/j.1471-4159.2000.0750634.x 1:CAS:528: DC%2BD3cXltFClt7c%3D
-
V Tancredi M D'Antuono C Cafe S Giovedi MC Bue G D'Arcangelo F Onofri F Benfenati 2000 The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK J Neurochem 75 634 643 10899938 10.1046/j.1471-4159.2000. 0750634.x 1:CAS:528:DC%2BD3cXltFClt7c%3D
-
(2000)
J Neurochem
, vol.75
, pp. 634-643
-
-
Tancredi, V.1
D'Antuono, M.2
Cafe, C.3
Giovedi, S.4
Bue, M.C.5
D'Arcangelo, G.6
Onofri, F.7
Benfenati, F.8
-
307
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
15734686 10.1016/j.cell.2005.02.008 1:CAS:528:DC%2BD2MXitVWnu7k%3D
-
RE Tanzi L Bertram 2005 Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective Cell 120 545 555 15734686 10.1016/j.cell.2005. 02.008 1:CAS:528:DC%2BD2MXitVWnu7k%3D
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
308
-
-
0029964265
-
Chromogranin a triggers a phenotypic transformation and the generation of nitric oxide in brain microglial cells
-
8737408 10.1016/0306-4522(96)83172-1 1:CAS:528:DyaK28XisFCksrg%3D
-
L Taupenot J CiesielskiTreska G Ulrich S ChasserotGolaz D Aunis MF Bader 1996 Chromogranin a triggers a phenotypic transformation and the generation of nitric oxide in brain microglial cells Neuroscience 72 377 389 8737408 10.1016/0306-4522(96)83172-1 1:CAS:528:DyaK28XisFCksrg%3D
-
(1996)
Neuroscience
, vol.72
, pp. 377-389
-
-
Taupenot, L.1
Ciesielskitreska, J.2
Ulrich, G.3
Chasserotgolaz, S.4
Aunis, D.5
Bader, M.F.6
-
309
-
-
0034618113
-
A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo
-
10934224 10.1084/jem.192.3.359 1:CAS:528:DC%2BD3cXlsFygt70%3D
-
PR Taylor A Carugati VA Fadok HT Cook M Andrews MC Carroll JS Savill PM Henson M Botto MJ Walport 2000 A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo J Exp Med 192 359 366 10934224 10.1084/jem.192.3.359 1:CAS:528:DC%2BD3cXlsFygt70%3D
-
(2000)
J Exp Med
, vol.192
, pp. 359-366
-
-
Taylor, P.R.1
Carugati, A.2
Fadok, V.A.3
Cook, H.T.4
Andrews, M.5
Carroll, M.C.6
Savill, J.S.7
Henson, P.M.8
Botto, M.9
Walport, M.J.10
-
310
-
-
0028203479
-
TNF alpha gene expression is induced in neurones after a hippocampal lesion
-
8025249 10.1097/00001756-199401000-00013 1:STN:280:DyaK2c3pslWrsA%3D%3D
-
JL Tchelingerian L Vignais C Jacque 1994 TNF alpha gene expression is induced in neurones after a hippocampal lesion Neuroreport 5 585 588 8025249 10.1097/00001756-199401000-00013 1:STN:280:DyaK2c3pslWrsA%3D%3D
-
(1994)
Neuroreport
, vol.5
, pp. 585-588
-
-
Tchelingerian, J.L.1
Vignais, L.2
Jacque, C.3
-
311
-
-
0037440372
-
Alzheimer's disease is associated with a selective increase in alpha 7 nicotinic acetylcholine receptor immunoreactivity in astrocytes
-
12509811 10.1002/glia.10132
-
T Teaktong A Graham J Court R Perry E Jaros M Johnson R Hall E Perry 2003 Alzheimer's disease is associated with a selective increase in alpha 7 nicotinic acetylcholine receptor immunoreactivity in astrocytes Glia 41 207 211 12509811 10.1002/glia.10132
-
(2003)
Glia
, vol.41
, pp. 207-211
-
-
Teaktong, T.1
Graham, A.2
Court, J.3
Perry, R.4
Jaros, E.5
Johnson, M.6
Hall, R.7
Perry, E.8
-
312
-
-
21144447586
-
A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment
-
15742005 10.1038/sj.npp.1300690 1:CAS:528:DC%2BD2MXltlWmt7c%3D
-
LJ Thal SH Ferris L Kirby GA Block CR Lines E Yuen C Assaid ML Nessly BA Norman CC Baranak SA Reines 2005 A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment Neuropsychopharmacology 30 1204 1215 15742005 10.1038/sj.npp.1300690 1:CAS:528:DC%2BD2MXltlWmt7c%3D
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1204-1215
-
-
Thal, L.J.1
Ferris, S.H.2
Kirby, L.3
Block, G.A.4
Lines, C.R.5
Yuen, E.6
Assaid, C.7
Nessly, M.L.8
Norman, B.A.9
Baranak, C.C.10
Reines, S.A.11
-
313
-
-
0026722679
-
Interleukin-1 and tumor-necrosis-factor-alpha stimulate the production of colony-stimulating factor-I by murine astrocytes
-
1494907 10.1111/j.1471-4159.1992.tb08366.x 1:CAS:528:DyaK38XlsV2jtLc%3D
-
C Thery ER Stanley M Mallat 1992 Interleukin-1 and tumor-necrosis-factor- alpha stimulate the production of colony-stimulating factor-I by murine astrocytes J Neurochem 59 1183 1186 1494907 10.1111/j.1471-4159.1992.tb08366.x 1:CAS:528:DyaK38XlsV2jtLc%3D
-
(1992)
J Neurochem
, vol.59
, pp. 1183-1186
-
-
Thery, C.1
Stanley, E.R.2
Mallat, M.3
-
314
-
-
0028248331
-
The role of the l-arginine: Nitric oxide pathway in circulatory shock
-
Thiemermann C (1994) The role of the l-arginine: nitric oxide pathway in circulatory shock. Adv Pharmacol 28:45-79
-
(1994)
Adv Pharmacol
, vol.28
, pp. 45-79
-
-
Thiemermann, C.1
-
315
-
-
0035968743
-
Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation
-
11711868 10.1097/00001756-200110290-00024 1:CAS:528:DC%2BD3MXotl2isrk%3D
-
T Thomas TG Nadackal K Thomas 2001 Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation Neuroreport 12 3263 3267 11711868 10.1097/00001756-200110290-00024 1:CAS:528:DC%2BD3MXotl2isrk%3D
-
(2001)
Neuroreport
, vol.12
, pp. 3263-3267
-
-
Thomas, T.1
Nadackal, T.G.2
Thomas, K.3
-
316
-
-
0031127741
-
Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: Implications for Alzheimer's disease
-
9168834 10.1006/exnr.1997.6429 1:CAS:528:DyaK2sXjtlOjuro%3D
-
G Tocco J Freire-Moar SS Schreiber SH Sakhi PS Aisen GM Pasinetti 1997 Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease Exp Neurol 144 339 349 9168834 10.1006/exnr.1997.6429 1:CAS:528:DyaK2sXjtlOjuro%3D
-
(1997)
Exp Neurol
, vol.144
, pp. 339-349
-
-
Tocco, G.1
Freire-Moar, J.2
Schreiber, S.S.3
Sakhi, S.H.4
Aisen, P.S.5
Pasinetti, G.M.6
-
317
-
-
0028180070
-
MPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
-
7926726 10.1101/gad.8.10.1224 1:CAS:528:DyaK2cXlsFSgsbc%3D
-
P Tontonoz E Hu RA Graves AI Budavari BM Spiegelman 1994 mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer Genes Dev 8 1224 1234 7926726 10.1101/gad.8.10.1224 1:CAS:528:DyaK2cXlsFSgsbc%3D
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
318
-
-
0026541591
-
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
-
1537328 1:CAS:528:DyaK3sXhtFyjsLk%3D
-
JD Tugwood I Issemann RG Anderson KR Bundell WL McPheat S Green 1992 The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene EMBO J 11 433 439 1537328 1:CAS:528:DyaK3sXhtFyjsLk%3D
-
(1992)
EMBO J
, vol.11
, pp. 433-439
-
-
Tugwood, J.D.1
Issemann, I.2
Anderson, R.G.3
Bundell, K.R.4
McPheat, W.L.5
Green, S.6
-
319
-
-
4944258716
-
The role of inflammation in Alzheimer's disease
-
15474976 10.1016/j.biocel.2004.07.009 1:CAS:528:DC%2BD2cXotlCntbw%3D
-
EE Tuppo HR Arias 2005 The role of inflammation in Alzheimer's disease Int J Biochem Cell Biol 37 289 305 15474976 10.1016/j.biocel.2004.07.009 1:CAS:528:DC%2BD2cXotlCntbw%3D
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 289-305
-
-
Tuppo, E.E.1
Arias, H.R.2
-
320
-
-
37349069999
-
Toll-like receptors 2 and 4 mediate Abeta(1-42) activation of the innate immune response in a human monocytic cell line
-
17986235 1:CAS:528:DC%2BD1cXhtlSqs7c%3D
-
ML Udan D Ajit NR Crouse MR Nichols 2008 Toll-like receptors 2 and 4 mediate Abeta(1-42) activation of the innate immune response in a human monocytic cell line J Neurochem 104 524 533 17986235 1:CAS:528: DC%2BD1cXhtlSqs7c%3D
-
(2008)
J Neurochem
, vol.104
, pp. 524-533
-
-
Udan, M.L.1
Ajit, D.2
Crouse, N.R.3
Nichols, M.R.4
-
321
-
-
0033542873
-
Medical significance of peroxisome proliferator-activated receptors
-
10408502 10.1016/S0140-6736(98)10364-1 1:CAS:528:DyaK1MXkvFeitbc%3D
-
J Vamecq N Latruffe 1999 Medical significance of peroxisome proliferator-activated receptors Lancet 354 141 148 10408502 10.1016/S0140-6736(98)10364-1 1:CAS:528:DyaK1MXkvFeitbc%3D
-
(1999)
Lancet
, vol.354
, pp. 141-148
-
-
Vamecq, J.1
Latruffe, N.2
-
322
-
-
0037791771
-
Activation of complement in the central nervous system: Roles in neurodegeneration and neuroprotection
-
van Beek J, Elward K, Gasque P (2003) Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection. Ann N Y Acad Sci 992:56-71
-
(2003)
Ann N y Acad Sci
, vol.992
, pp. 56-71
-
-
Van Beek, J.1
Elward, K.2
Gasque, P.3
-
323
-
-
72849109858
-
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
-
19907078 1:CAS:528:DC%2BD1MXhsFCit7nO
-
NH Varvel K Bhaskar MZ Kounnas SL Wagner Y Yang BT Lamb K Herrup 2009 NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease J Clin Invest 119 3692 3702 19907078 1:CAS:528: DC%2BD1MXhsFCit7nO
-
(2009)
J Clin Invest
, vol.119
, pp. 3692-3702
-
-
Varvel, N.H.1
Bhaskar, K.2
Kounnas, M.Z.3
Wagner, S.L.4
Yang, Y.5
Lamb, B.T.6
Herrup, K.7
-
324
-
-
17444390124
-
Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q
-
15837583 10.1016/j.nbd.2005.01.005 1:CAS:528:DC%2BD2MXjtlajtrY%3D
-
R Veerhuis RS Boshuizen M Morbin G Mazzoleni JJM Hoozemans JPM Langedijk F Tagliavini JPM Langeveld P Eikelenboom 2005 Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q Neurobiol Dis 19 273 282 15837583 10.1016/j.nbd.2005.01.005 1:CAS:528:DC%2BD2MXjtlajtrY%3D
-
(2005)
Neurobiol Dis
, vol.19
, pp. 273-282
-
-
Veerhuis, R.1
Boshuizen, R.S.2
Morbin, M.3
Mazzoleni, G.4
Hoozemans, J.J.M.5
Langedijk, J.P.M.6
Tagliavini, F.7
Langeveld, J.P.M.8
Eikelenboom, P.9
-
325
-
-
10244235267
-
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease
-
8879214 10.1084/jem.184.4.1425 1:CAS:528:DyaK28XmtlKhsrk%3D
-
Y Vodovotz MS Lucia KC Flanders L Chesler QW Xie TW Smith J Weidner R Mumford R Webber C Nathan AB Roberts CF Lippa MB Sporn 1996 Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease J Exp Med 184 1425 1433 8879214 10.1084/jem.184.4.1425 1:CAS:528: DyaK28XmtlKhsrk%3D
-
(1996)
J Exp Med
, vol.184
, pp. 1425-1433
-
-
Vodovotz, Y.1
Lucia, M.S.2
Flanders, K.C.3
Chesler, L.4
Xie, Q.W.5
Smith, T.W.6
Weidner, J.7
Mumford, R.8
Webber, R.9
Nathan, C.10
Roberts, A.B.11
Lippa, C.F.12
Sporn, M.B.13
-
326
-
-
0031127418
-
Nitric oxide synthase in reactive astrocytes adjacent to beta-amyloid plaques
-
9168828 10.1006/exnr.1996.6373 1:CAS:528:DyaK2sXjtlOjtbY%3D
-
MN Wallace JG Geddes DA Farquhar MR Masson 1997 Nitric oxide synthase in reactive astrocytes adjacent to beta-amyloid plaques Exp Neurol 144 266 272 9168828 10.1006/exnr.1996.6373 1:CAS:528:DyaK2sXjtlOjtbY%3D
-
(1997)
Exp Neurol
, vol.144
, pp. 266-272
-
-
Wallace, M.N.1
Geddes, J.G.2
Farquhar, D.A.3
Masson, M.R.4
-
327
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
15450169 10.1016/j.neuron.2004.09.010 1:CAS:528:DC%2BD2cXovVOks78%3D
-
DM Walsh DJ Selkoe 2004 Deciphering the molecular basis of memory failure in Alzheimer's disease Neuron 44 181 193 15450169 10.1016/j.neuron.2004.09.010 1:CAS:528:DC%2BD2cXovVOks78%3D
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
328
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
11932745 10.1038/416535a 1:CAS:528:DC%2BD38XivVOntL8%3D
-
DM Walsh I Klyubin JV Fadeeva WK Cullen R Anwyl MS Wolfe MJ Rowan DJ Selkoe 2002 Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo Nature 416 535 539 11932745 10.1038/416535a 1:CAS:528:DC%2BD38XivVOntL8%3D
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
329
-
-
0036669881
-
Amyloid-beta oligomers: Their production, toxicity and therapeutic inhibition
-
12196135 10.1042/BST0300552 1:CAS:528:DC%2BD38XntVentLk%3D
-
DM Walsh I Klyubin JV Fadeeva MJ Rowan DJ Selkoe 2002 Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition Biochem Soc Trans 30 552 557 12196135 10.1042/BST0300552 1:CAS:528:DC%2BD38XntVentLk%3D
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 552-557
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Rowan, M.J.4
Selkoe, D.J.5
-
330
-
-
0035805592
-
Phosphorylation regulates intracellular trafficking of beta-secretase
-
11278841 10.1074/jbc.M011116200 1:CAS:528:DC%2BD3MXjs1Oktb8%3D
-
J Walter R Fluhrer B Hartung M Willem C Kaether A Capell S Lammich G Multhaup C Haass 2001 Phosphorylation regulates intracellular trafficking of beta-secretase J Biol Chem 276 14634 14641 11278841 10.1074/jbc.M011116200 1:CAS:528:DC%2BD3MXjs1Oktb8%3D
-
(2001)
J Biol Chem
, vol.276
, pp. 14634-14641
-
-
Walter, J.1
Fluhrer, R.2
Hartung, B.3
Willem, M.4
Kaether, C.5
Capell, A.6
Lammich, S.7
Multhaup, G.8
Haass, C.9
-
331
-
-
35848963223
-
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease
-
17982277 10.1159/000110455 1:CAS:528:DC%2BD2sXht1Cku7zP
-
S Walter M Letiembre Y Liu H Heine B Penke W Hao B Bode N Manietta J Walter W Schulz-Schuffer K Fassbender 2007 Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease Cell Physiol Biochem 20 947 956 17982277 10.1159/000110455 1:CAS:528:DC%2BD2sXht1Cku7zP
-
(2007)
Cell Physiol Biochem
, vol.20
, pp. 947-956
-
-
Walter, S.1
Letiembre, M.2
Liu, Y.3
Heine, H.4
Penke, B.5
Hao, W.6
Bode, B.7
Manietta, N.8
Walter, J.9
Schulz-Schuffer, W.10
Fassbender, K.11
-
332
-
-
0037461768
-
Nicotinic acetylcholine receptor alpha 7 subunit is an essential regulator of inflammation
-
12508119 10.1038/nature01339 1:CAS:528:DC%2BD3sXlsVantA%3D%3D
-
H Wang M Yu M Ochani CA Amella M Tanovic S Susarla JH Li HC Wang H Yang L Ulloa Y Al Abed CJ Czura KJ Tracey 2003 Nicotinic acetylcholine receptor alpha 7 subunit is an essential regulator of inflammation Nature 421 384 388 12508119 10.1038/nature01339 1:CAS:528:DC%2BD3sXlsVantA%3D%3D
-
(2003)
Nature
, vol.421
, pp. 384-388
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
Amella, C.A.4
Tanovic, M.5
Susarla, S.6
Li, J.H.7
Wang, H.C.8
Yang, H.9
Ulloa, L.10
Al Abed, Y.11
Czura, C.J.12
Tracey, K.J.13
-
333
-
-
3042798841
-
Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
-
15240796 10.1523/JNEUROSCI.0233-04.2004 1:CAS:528:DC%2BD2cXlvFKrtLg%3D
-
Q Wang MJ Rowan R Anwyl 2004 Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide J Neurosci 24 6049 6056 15240796 10.1523/JNEUROSCI.0233-04.2004 1:CAS:528:DC%2BD2cXlvFKrtLg%3D
-
(2004)
J Neurosci
, vol.24
, pp. 6049-6056
-
-
Wang, Q.1
Rowan, M.J.2
Anwyl, R.3
-
334
-
-
70449678686
-
NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits
-
19906966 10.1523/JNEUROSCI.3238-09.2009 1:CAS:528:DC%2BD1MXhsVGrsrvE
-
M Weberpals M Hermes S Hermann MP Kummer D Terwel A Semmler M Berger M Schafers MT Heneka 2009 NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits J Neurosci 29 14177 14184 19906966 10.1523/JNEUROSCI.3238-09.2009 1:CAS:528:DC%2BD1MXhsVGrsrvE
-
(2009)
J Neurosci
, vol.29
, pp. 14177-14184
-
-
Weberpals, M.1
Hermes, M.2
Hermann, S.3
Kummer, M.P.4
Terwel, D.5
Semmler, A.6
Berger, M.7
Schafers, M.8
Heneka, M.T.9
-
335
-
-
0030978135
-
Charge-based binding of complement component C1q to the Alzheimer amyloid beta-peptide
-
9137079 1:CAS:528:DyaK2sXjtlertLw%3D
-
S Webster B Bonnell J Rogers 1997 Charge-based binding of complement component C1q to the Alzheimer amyloid beta-peptide Am J Pathol 150 1531 1536 9137079 1:CAS:528:DyaK2sXjtlertLw%3D
-
(1997)
Am J Pathol
, vol.150
, pp. 1531-1536
-
-
Webster, S.1
Bonnell, B.2
Rogers, J.3
-
336
-
-
0030817147
-
Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease
-
9330973 10.1016/S0197-4580(97)00042-0 1:CAS:528:DyaK2sXmslChtL8%3D
-
S Webster LF Lue L Brachova AJ Tenner PL McGeer K Terai DG Walker B Bradt NR Cooper J Rogers 1997 Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease Neurobiol Aging 18 415 421 9330973 10.1016/S0197-4580(97)00042-0 1:CAS:528:DyaK2sXmslChtL8%3D
-
(1997)
Neurobiol Aging
, vol.18
, pp. 415-421
-
-
Webster, S.1
Lue, L.F.2
Brachova, L.3
Tenner, A.J.4
McGeer, P.L.5
Terai, K.6
Walker, D.G.7
Bradt, B.8
Cooper, N.R.9
Rogers, J.10
-
337
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity
-
11700559 10.1038/35102591 1:CAS:528:DC%2BD3MXosFahsLc%3D
-
S Weggen JL Eriksen P Das SA Sagi R Wang CU Pietrzik KA Findlay TE Smith MP Murphy T Bulter DE Kang N Marquez-Sterling TE Golde EH Koo 2001 A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity Nature 414 212 216 11700559 10.1038/35102591 1:CAS:528:DC%2BD3MXosFahsLc%3D
-
(2001)
Nature
, vol.414
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrzik, C.U.6
Findlay, K.A.7
Smith, T.E.8
Murphy, M.P.9
Bulter, T.10
Kang, D.E.11
Marquez-Sterling, N.12
Golde, T.E.13
Koo, E.H.14
-
338
-
-
0032521111
-
Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo
-
9482801 1:CAS:528:DyaK1cXhs1ylsLk%3D
-
DT Weldon SD Rogers JR Ghilardi MP Finke JP Cleary E O'Hare WP Esler JE Maggio PW Mantyh 1998 Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo J Neurosci 18 2161 2173 9482801 1:CAS:528:DyaK1cXhs1ylsLk%3D
-
(1998)
J Neurosci
, vol.18
, pp. 2161-2173
-
-
Weldon, D.T.1
Rogers, S.D.2
Ghilardi, J.R.3
Finke, M.P.4
Cleary, J.P.5
O'Hare, E.6
Esler, W.P.7
Maggio, J.E.8
Mantyh, P.W.9
-
339
-
-
0023952347
-
The differential involvement of subcortical nuclei in senile dementia of Alzheimer's type
-
3404192 10.1136/jnnp.51.6.842 1:STN:280:DyaL1czgtVWjtA%3D%3D
-
GK Wilcock MM Esiri DM Bowen AO Hughes 1988 The differential involvement of subcortical nuclei in senile dementia of Alzheimer's type J Neurol Neurosurg Psychiatry 51 842 849 3404192 10.1136/jnnp.51.6.842 1:STN:280: DyaL1czgtVWjtA%3D%3D
-
(1988)
J Neurol Neurosurg Psychiatry
, vol.51
, pp. 842-849
-
-
Wilcock, G.K.1
Esiri, M.M.2
Bowen, D.M.3
Hughes, A.O.4
-
340
-
-
0033571331
-
IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
-
10553050 1:CAS:528:DyaK1MXntlKku7Y%3D
-
DO Willenborg SA Fordham MA Staykova IA Ramshaw WB Cowden 1999 IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide J Immunol 163 5278 5286 10553050 1:CAS:528:DyaK1MXntlKku7Y%3D
-
(1999)
J Immunol
, vol.163
, pp. 5278-5286
-
-
Willenborg, D.O.1
Fordham, S.A.2
Staykova, M.A.3
Ramshaw, I.A.4
Cowden, W.B.5
-
341
-
-
0033400628
-
Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: A review
-
10695712 10.1016/S0165-5728(99)00212-X 1:CAS:528:DC%2BD3cXltVeisA%3D%3D
-
DO Willenborg MA Staykova WB Cowden 1999 Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: a review J Neuroimmunol 100 21 35 10695712 10.1016/S0165-5728(99)00212-X 1:CAS:528:DC%2BD3cXltVeisA%3D%3D
-
(1999)
J Neuroimmunol
, vol.100
, pp. 21-35
-
-
Willenborg, D.O.1
Staykova, M.A.2
Cowden, W.B.3
-
342
-
-
0030764732
-
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease
-
9335500 10.1038/39321 1:CAS:528:DyaK2sXmslWgu70%3D
-
T Wyss-Coray E Masliah M Mallory L McConlogue K Johnson-Wood C Lin L Mucke 1997 Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease Nature 389 603 606 9335500 10.1038/39321 1:CAS:528:DyaK2sXmslWgu70%3D
-
(1997)
Nature
, vol.389
, pp. 603-606
-
-
Wyss-Coray, T.1
Masliah, E.2
Mallory, M.3
McConlogue, L.4
Johnson-Wood, K.5
Lin, C.6
Mucke, L.7
-
343
-
-
0033900999
-
Chronic overproduction of transforming growth factor-beta 1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice
-
10623661 1:CAS:528:DC%2BD3cXns1yltg%3D%3D
-
T Wyss-Coray C Lin DA Sanan L Mucke E Masliah 2000 Chronic overproduction of transforming growth factor-beta 1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice Am J Pathol 156 139 150 10623661 1:CAS:528:DC%2BD3cXns1yltg%3D%3D
-
(2000)
Am J Pathol
, vol.156
, pp. 139-150
-
-
Wyss-Coray, T.1
Lin, C.2
Sanan, D.A.3
Mucke, L.4
Masliah, E.5
-
344
-
-
0036679142
-
Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice
-
12119423 10.1073/pnas.162350199 1:CAS:528:DC%2BD38Xmt1ChtLY%3D
-
T Wyss-Coray F Yan AH Lin JD Lambris JJ Alexander RJ Quigg E Masliah 2002 Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice Proc Natl Acad Sci USA 99 10837 10842 12119423 10.1073/pnas.162350199 1:CAS:528:DC%2BD38Xmt1ChtLY%3D
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10837-10842
-
-
Wyss-Coray, T.1
Yan, F.2
Lin, A.H.3
Lambris, J.D.4
Alexander, J.J.5
Quigg, R.J.6
Masliah, E.7
-
345
-
-
0037394788
-
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ
-
12612547 10.1038/nm838 1:CAS:528:DC%2BD3sXisVOmurc%3D
-
T Wyss-Coray JD Loike TC Brionne E Lu R Anankov F Yan SC Silverstein J Husemann 2003 Adult mouse astrocytes degrade amyloid-beta in vitro and in situ Nat Med 9 453 457 12612547 10.1038/nm838 1:CAS:528:DC%2BD3sXisVOmurc%3D
-
(2003)
Nat Med
, vol.9
, pp. 453-457
-
-
Wyss-Coray, T.1
Loike, J.D.2
Brionne, T.C.3
Lu, E.4
Anankov, R.5
Yan, F.6
Silverstein, S.C.7
Husemann, J.8
-
346
-
-
0032917904
-
Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
-
10190688 10.3109/13550289909029743 1:CAS:528:DyaK1MXht1WmtLc%3D
-
MQ Xia BT Hyman 1999 Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease J Neurovirol 5 32 41 10190688 10.3109/13550289909029743 1:CAS:528:DyaK1MXht1WmtLc%3D
-
(1999)
J Neurovirol
, vol.5
, pp. 32-41
-
-
Xia, M.Q.1
Hyman, B.T.2
-
347
-
-
0031848322
-
Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains
-
9665462 1:CAS:528:DyaK1cXks1Grs7o%3D
-
MQ Xia SX Qin LJ Wu CR Mackay BT Hyman 1998 Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains Am J Pathol 153 31 37 9665462 1:CAS:528: DyaK1cXks1Grs7o%3D
-
(1998)
Am J Pathol
, vol.153
, pp. 31-37
-
-
Xia, M.Q.1
Qin, S.X.2
Wu, L.J.3
MacKay, C.R.4
Hyman, B.T.5
-
348
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neurons-regulation by synaptic activity and glucocorticoids
-
8352945 10.1016/0896-6273(93)90192-T 1:CAS:528:DyaK2cXht1Ghu7k%3D
-
K Yamagata KI Andreasson WE Kaufmann CA Barnes PF Worley 1993 Expression of a mitogen-inducible cyclooxygenase in brain neurons-regulation by synaptic activity and glucocorticoids Neuron 11 371 386 8352945 10.1016/0896-6273(93) 90192-T 1:CAS:528:DyaK2cXht1Ghu7k%3D
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.I.2
Kaufmann, W.E.3
Barnes, C.A.4
Worley, P.F.5
-
349
-
-
0029076397
-
Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide
-
7585153 10.1038/nm0795-693 1:CAS:528:DyaK2MXms1Kgtr8%3D
-
SD Yan SF Yan X Chen J Fu M Chen P Kuppusamy MA Smith G Perry GC Godman P Nawroth 1995 Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide Nat Med 1 693 699 7585153 10.1038/nm0795-693 1:CAS:528:DyaK2MXms1Kgtr8%3D
-
(1995)
Nat Med
, vol.1
, pp. 693-699
-
-
Yan, S.D.1
Yan, S.F.2
Chen, X.3
Fu, J.4
Chen, M.5
Kuppusamy, P.6
Smith, M.A.7
Perry, G.8
Godman, G.C.9
Nawroth, P.10
-
351
-
-
0041921071
-
Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease
-
12930788 1:CAS:528:DC%2BD3sXmvFaisLg%3D
-
Q Yan J Zhang H Liu S Babu-Khan R Vassar AL Biere M Citron G Landreth 2003 Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease J Neurosci 23 7504 7509 12930788 1:CAS:528:DC%2BD3sXmvFaisLg%3D
-
(2003)
J Neurosci
, vol.23
, pp. 7504-7509
-
-
Yan, Q.1
Zhang, J.2
Liu, H.3
Babu-Khan, S.4
Vassar, R.5
Biere, A.L.6
Citron, M.7
Landreth, G.8
-
352
-
-
0033526660
-
Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs
-
10366679 10.1016/S0006-8993(99)01389-X 1:CAS:528:DyaK1MXjtl2qsLk%3D
-
K Yasojima C Schwab EG McGeer PL McGeer 1999 Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs Brain Res 830 226 236 10366679 10.1016/S0006-8993(99)01389-X 1:CAS:528:DyaK1MXjtl2qsLk%3D
-
(1999)
Brain Res
, vol.830
, pp. 226-236
-
-
Yasojima, K.1
Schwab, C.2
McGeer, E.G.3
McGeer, P.L.4
-
353
-
-
0033061855
-
Up-regulated production and activation of the complement system in Alzheimer's disease brain
-
10079271 1:CAS:528:DyaK1MXitVelur0%3D
-
K Yasojima C Schwab EG McGeer PL McGeer 1999 Up-regulated production and activation of the complement system in Alzheimer's disease brain Am J Pathol 154 927 936 10079271 1:CAS:528:DyaK1MXitVelur0%3D
-
(1999)
Am J Pathol
, vol.154
, pp. 927-936
-
-
Yasojima, K.1
Schwab, C.2
McGeer, E.G.3
McGeer, P.L.4
-
354
-
-
0021049766
-
Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome
-
6228286 10.1016/0006-8993(83)91179-4 1:CAS:528:DyaL2cXitFaguw%3D%3D
-
CM Yates J Simpson A Gordon AF Maloney Y Allison IM Ritchie A Urquhart 1983 Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome Brain Res 280 119 126 6228286 10.1016/0006-8993(83)91179-4 1:CAS:528:DyaL2cXitFaguw%3D%3D
-
(1983)
Brain Res
, vol.280
, pp. 119-126
-
-
Yates, C.M.1
Simpson, J.2
Gordon, A.3
Maloney, A.F.4
Allison, Y.5
Ritchie, I.M.6
Urquhart, A.7
-
355
-
-
0033694033
-
Cyclooxygenases in the central nervous system: Implications for treatment of neurological disorders
-
11203433 10.2174/1381612003398672 1:CAS:528:DC%2BD3cXosVGlt7k%3D
-
A Yermakova MK O'Banion 2000 Cyclooxygenases in the central nervous system: implications for treatment of neurological disorders Curr Pharm Des 6 1755 1776 11203433 10.2174/1381612003398672 1:CAS:528:DC%2BD3cXosVGlt7k%3D
-
(2000)
Curr Pharm des
, vol.6
, pp. 1755-1776
-
-
Yermakova, A.1
O'Banion, M.K.2
-
356
-
-
0035693794
-
Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease
-
11754989 10.1016/S0197-4580(01)00303-7 1:CAS:528:DC%2BD3MXptFyluro%3D
-
AV Yermakova MK O'Banion 2001 Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease Neurobiol Aging 22 823 836 11754989 10.1016/S0197-4580(01)00303-7 1:CAS:528:DC%2BD3MXptFyluro%3D
-
(2001)
Neurobiol Aging
, vol.22
, pp. 823-836
-
-
Yermakova, A.V.1
O'Banion, M.K.2
-
357
-
-
0032725481
-
Cyclooxygenase-1 in human Alzheimer and control brain: Quantitative analysis of expression by microglia and CA3 hippocampal neurons
-
10560656 10.1097/00005072-199911000-00003 1:CAS:528:DyaK1MXnvVartrY%3D
-
AV Yermakova J Rollins LM Callahan J Rogers MK O'Banion 1999 Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons J Neuropathol Exp Neurol 58 1135 1146 10560656 10.1097/00005072-199911000-00003 1:CAS:528:DyaK1MXnvVartrY%3D
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1135-1146
-
-
Yermakova, A.V.1
Rollins, J.2
Callahan, L.M.3
Rogers, J.4
O'Banion, M.K.5
-
358
-
-
19244365650
-
Thiazolidinediones
-
15356308 10.1056/NEJMra041001
-
H Yki-Jarvinen 2004 Thiazolidinediones N Engl J Med 351 1106 1118 15356308 10.1056/NEJMra041001
-
(2004)
N Engl J Med
, vol.351
, pp. 1106-1118
-
-
Yki-Jarvinen, H.1
-
359
-
-
0037337815
-
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
-
12633144 10.1001/archneur.60.3.337
-
C Zarow SA Lyness JA Mortimer HC Chui 2003 Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases Arch Neurol 60 337 341 12633144 10.1001/archneur.60.3.337
-
(2003)
Arch Neurol
, vol.60
, pp. 337-341
-
-
Zarow, C.1
Lyness, S.A.2
Mortimer, J.A.3
Chui, H.C.4
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