In vitro and in vivo oxidative stress associated with Alzheimer's amyloid β-peptide (1-42)

Neurobiology of Aging

Volumn 20, Issue 3, 1999, Pages 325-330

  Yatin, Servet M ^a   Varadarajan, Sridhar ^a   Link, Christopher D ^b   Butterfield, D Allan ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; Amyloid peptide; C. elegans; Cell culture; Free radical; Methionine; Protein oxidation

Indexed keywords

AMYLOID BETA PROTEIN; CARBONYL DERIVATIVE; FREE RADICAL; METHIONINE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; NERVE DEGENERATION; NEUROTOXICITY; NEWBORN; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPIN TRAPPING;

EID: 0033133579     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(99)00056-1     Document Type: Note

References (47)

1. [1] Aksenov MY, Aksenova MV, Carney JM, Butterfield DA. Oxidative modification of glutamine synthetase by amyloid β-peptide. Free Rad Res 1997;27:267-81.
2. [2] Beal MF. Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann Neurol 1992;31: 119-30.
3. [3] Beal MF. Aging, energy and oxidative stress in neurodegenerative diseases. Ann Neurol 1995;38:357-66.
4. [4] Behl C, Davis J, Cole GM, Shubert D. Vitamin E protects nerve cells from amyloid β protein toxicity. Biochem Biophys Res Commun 1992;186:944-50.
5. [5] Behl C, Davis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid β protein toxicity. Cell 1994;77:817-27.
6. [6] Brewer GJ, Torricelli JR, Evege EK, Price PJ. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res 1993;35:567-76.
7. [7] Bruce AJ, Malfroy B, Baudry M. β-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc Natl Acad Sci USA 1996;93:2312-16.
8. [8] Butterfield DA. β-amyloid-associated free radical oxidative stress and neurotoxicity: implications for Alzheimer's disease. Chem Res Toxicol 1997;10:495-506.
9. [9] Butterfield DA, Stadtman ER. Protein oxidation process in aging brain. Adv Cell Aging Gerontol 1997;2:161-91.
10. [10] Davis JB. Oxidative mechanisms in β-amyloid cytotoxicity. Neurodegeneration 1996;5:441-4.
11. [11] Dyrks T, Hartmann T, Masters C, Beyreuther K. Amyloidgenicity of βA4 and βA4-bearing amyloid precursor fragments by metal-catalyzed oxidation. J Biol Chem 1992;267:18210-17.
12. [12] Fay DS, Fluet A, Johnson CJ, Link CD. In vivo aggregation of β-amyloid peptide variants. J Neurochem 1998;71:1616-25.
13. [13] Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F, Guido T, Hagoplan S, Johnson-Wood K, Khan K, Lee M, Leibowitz P, Lierburg I, Little S, Masliah E, McConlogue L, Montoya-Zavala M, Mucke L, Paganini L, Penniman E, Power M, Schenk D, Seubert P, Synmder B, Soriano F, Tan F, Vital J, Wadsworth S, Wolozin B, Zhao J. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 1995;373:523-7.
14. [14] Glenney JR. Antibody probing on Western blots have been stained with India ink. Anal Biochem 1986;156:315-18.
15. [15] Goate A, Chartier-Harlin M-C, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor M, Owen M, Hardy J. Segregation of missense mutation in the amyloid precursor protein. Biochem Biophys Res Commun 1991;155:608-14.
16. [16] Guo Q, Robinson N, Mattson MP. Secreted β-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NFκB and stabilization of calcium homeostasis. J Biol Chem 273;1998:12341-51.
17. [17] Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski BL, Lieberburg I, Koo EH, Schenk D, Teplow DB, Selkoe DJ. Amyloid β-peptide is produced by cultured cells during normal metabolism. Nature 1992;359:322-5.
18. [18] Harris M, Hensley K, Butterfield DA, Leedle RA, Carney JM. Direct evidence of oxidative injury produced by the Alzheimer's β amyloid peptide (1-40) in cultured hippocampal neurons. Exp Neurol 1995; 131:193-202.
19. [19] Hensley K, Carney JM, Mattsonm MP, Aksenova MV, Harris ME, Wu JF, Floyd RA, Butterfield DA. A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer's disease. Proc Natl Acad Sci USA 1994;91: 3270-4.
20. [20] Hensley K, Hall N, Subramaniam R, Cole P, Harris M, Aksenova M, Aksenov M, Gabbita P, Carney J, Markesberry W, Butterfield DA. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. J Neurochem 1995;65: 2146-56.
21. [21] Huang X, Atwood CS, Goldstein LE, Hartshorn MA, Scarpa RC, Multhaup G, Cuajungco M, Moir RD, Tanzi RE, Bush AI. Metal- and oxygen-dependent generation of reactive oxygen species by Aβ: differential effects of carboxyl terminus and peptide variants. Neurobiol Aging 1998;19:S263.
22. [22] Koppal T, Subramaniam R, Drake J, Prasad MR, Butterfield DA. Vitamin E protects against Alzheimer's amyloid peptide (25-35)-induced changes in neocortical synaptosomal membrane lipid structure and composition. Brain Res 1998;786:270-3.
23. [23] Laemmli, U. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
24. [24] Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shaltiel S, Stadtman ER. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990;186:464-78.
25. [25] Levine RL, Williams JA, Stadtman ER, Shacter E. Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol 1994;233:346-57.
26. [26] Link CD. Expression of human β-amyloid peptide in transgenic Caenorhabditis elegans. Proc Natl Acad Sci USA 1995;92:9368-72.
27. [27] Lovell MA, Ehmann WD, Mattson MP, Markesbery WR. Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiol Aging 1997;18:457-61.
28. [28] Manelli AM, Puttfarcken PS. β-amyloid-induced toxicity in rat hippocampal cells: in vitro evidence for the involvement of free radicals. Brain Res Bulletin 1995;38:569-76.
29. [29] Mark R, Hensley K, Butterfield DA, Mattson MP. Amyloid β-peptide impairs ion-motive ATPase activities; evidence for a role in loss of neuronal Ca-homeostasis and cell death. J Neurosci 1995;15:6239-49.
30. [30] Markesbery WR, Lovell MA. Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol Aging 1998;19:33-6.
31. 2+ homeostasis Alzheimer's disease. Trends Neurosci 1993;16:409-14.
32. [32] Mattson MP, Begley JG, Mark RJ, Furukawa K. Aβ(25-35) induces rapid lysis of red blood cells: contrast with Aβ(1-42) and examination of underlying mechanisms. Brain Res 1997;771:147-53.
33. [33] Murrell J, Farlow M, Ghetti B, Benson M. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science 1991;254:97-9.
34. [34] Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. Aggregation-related toxicity of synthetic β-amyloid protein in hippocampal cultures. Eur J Pharmacol 1991;207:367-8.
35. [35] Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman CW. Structure-activity analyses of β-amyloid peptides: contributions of the β 25-35 region to aggregation and neurotoxicity. J Neurochem 1995;64:253-65.
36. [36] Richardson JS. Free radicals in the genesis of Alzheimer's disease. Ann N Y Acad Sci 1994;695:73-6.
37. [37] Schubert D, Behl C, Lesley R, Brack A, Dargusch R, Sagara Y, Kimura H. Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci USA 1995;92:1989-93.
38. [38] Selkoe DJ. The deposition of amyloid proteins in the aging mammalian brain: implications for Alzheimer's disease. Ann Med 1989;21: 73-6.
39. [39] Selkoe DJ. Amyloid beta-protein and the genetics of Alzheimer's disease. J Biol Chem 1996;271:18295-8.
40. [40] Sims NR, Finegan JM, Blass JP, Bowen DM, Neary D. Mitochondrial function in brain tissue in primary degenerative dementia. Brain Res 1987;436:30-8.
41. [41] Smith MA, Hirai K, Hsiao K, Pappolla MA, Harris PL, Siedlak SL, Tabaton M, Perry G. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress. J Neurochem 1998;70: 2212-15.
42. [42] Subramaniam R, Koppal T, Yatin S, Jordan B, Butterfield DA. The free radical antioxidant vitamin E protects cortical synaptosomal membrane proteins from amyloid β-peptide (25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease. Neurochem Res 1998;23:1403-10.
43. 2+ channels: a possible involvement of free radicals. J Neurochem 1997;68:265-71.
44. [44] Yankner BA, Mesulam MM. Seminars in medicine of the Beth Israel Hospital, Boston. β-amyloid and the pathogenesis of Alzheimer's disease. New Engl J Med 1991;325:1849-57.
45. [45] Yatin SM, Aksenov M, Butterfield DA. The antioxidant vitamin E modulates amyloid β-peptide induced creatine kinase activity inhibition and increased protein oxidation: implications for the free radical hypothesis of Alzheimer's disease. Neurochem Res 1999;24:427-35.
46. [46] Yatin SM, Aksenova M, Aksenov M, Markesbery WR, Aulick T, Butterfield DA. Amyloid β-peptide (25-35)-induced oxidative stress in neuronal hippocampal culture: temporal modulation of neuronal survival, protein oxidation, CK expression, ROS formation, and Cu, Zn. Mn SOD mRNA levels. J Molec Neurosci 1998;11:183-97.
47. [47] Yatin SM, Yatin M, Aulick T, Ain KB, Butterfiled DA. Alzheimer's Aβ-associated free radicals increase neuronal polyuamine uptake and ODC activity. Neurosci Lett 1999;263:17-20.