Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility

Asian Journal of Andrology

Volumn 6, Issue 1, 2004, Pages 59-65

  Garrido, Nicolás ^a   Meseguer, Marcos ^a   Simon, Carlos ^a,b   Pellicer, Antonio ^a,b,c   Remohi, José ^a,c  

^a INSTITUTO VALENCIANO DE INFERTILIDAD   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c HOSPITAL UNIVERSITARIO DR PESET   (Spain)

Author keywords

Antioxidants; Male fertility; Oxidative stress; Semen; Spermatozoa

Indexed keywords

ADRENALIN; ALPHA TOCOPHEROL; ANTIOXIDANT; CATALASE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; HYPOTAURINE; LACTIC ACID; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TAURINE;

COCHRANE LIBRARY; EMBASE; FERTILIZATION; HUMAN; IMMUNITY; MALE; MALE FERTILITY; MALE INFERTILITY; MEDICAL LITERATURE; MEDLINE; MOLECULAR BIOLOGY; OXIDATIVE STRESS; PREGNANCY; PUBLICATION; RESPIRATORY FUNCTION; REVIEW; SAMPLING; SCAVENGING SYSTEM; SCISEARCH; SEMEN ANALYSIS; SEMINAL PLASMA; SPERM; SPERMATOZOON;

ANTIOXIDANTS; FERTILITY; HUMANS; INFERTILITY, MALE; MALE; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SEMEN; SPERMATOZOA;

EID: 1842483365     PISSN: 1008682X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Carlsen E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during past 50 years. Br Med J 1992; 305: 609-13.
2. Auger J, Kuntsmann JM, Czyglik F, Jouannet P. Decline in semen quality among fertile men in Paris during the past 20 years. N Engl J Med 1995; 332: 281-5.
3. Bhardwaj A, Verma A, Majumdar S, Khanduja KL. Status of vitamin E and reduced glutathione in semen of oligozoospermic and azoospermic patients. Asian J Androl 2000; 2: 225-8.
4. World Health Organization. WHO laboratory Manual for the examination of human semen and sperm-cervical mucus interaction. 4th Edition. Cambridge: Cambridge University Press, 1999.
5. Saleh RA, Agarwal A. Oxidative stress and male infertility: from research bench to clinical practice. J Androl 2002; 23: 737-52.
6. Agarwal A, Saleh RA, Bedaiwy MA. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 2003; 79: 829-43.
7. Fujii J, Iuchi Y, Matsuki S, Ishii T. Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues. Asian J Androl 2003; 5: 231-42.
8. Padron OF, Brackett NL, Sharma RK, Lynne CM, Thomas AJ Jr, Agarwal A. Seminal reactive oxygen species and sperm motility and morphology in men with spinal cord injury. Fertil Steril 1997; 67: 1115-20.
9. Sikka SC. Oxidative stress and role of antioxidants in normal and abnormal sperm function. Front Biosci 1996; 1: e78-86.
10. Gil-Guzman E, Ollero M, Lopez MC, Sharma RK, Alvarez JG, Thomas AJ Jr, et al. Differential production of reactive oxygen species by subsets of human spermatozoa at different stages of maturation. Hum Reprod 2001; 16: 1922-30.
11. Ollero M, Gil-Guzman E, Lopez MC, Sharma RK, Agarwal A, Larson K, et al. Characterization of subsets of human spermatozoa at different stages of maturation: implications in the diagnosis and treatment of male infertility. Hum Reprod 2001; 16: 1912-21.
12. Sharma RK, Pasqualotto AE, Nelson DR, Thomas AJ Jr, Agarwal A. Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic. J Androl 2001; 22: 575-83.
13. Saleh RA, Agarwal A, Kandirali E, Sharma RK, Thomas AJ, Nada EA, et al. Leukocytospermia is associated with increased reactive oxygen species production by human spermatozoa. Fertil Steril 2002; 78: 1215-24.
14. Mennella MR, Jones R. Properties of spermatozoal superoxide dismutase and lack of involvement of superoxides in metal-ion-catalysed lipid-peroxidation and reactions in semen. Biochem J 1980; 191: 289-97.
15. Kobayashi T, Miyazaki T, Natori M, Nozawa S. Protective role of superoxide dismutase in human sperm motility: superoxide dismutase activity and lipid peroxide in human seminal plasma and spermatozoa. Hum Reprod 1991; 6: 987-91.
16. Hsieh YY, Sun YL, Chang CC, Lee YS, Tsai HD, Lin CS. Superoxide dismutase activities of spermatozoa and seminal plasma are not correlated with male infertility. J Clin Lab Anal 2002; 16: 127-31.
17. Miesel R, Jedrzejczak P, Sanocka D, Kurpisz MK. Severe antioxidase deficiency in human semen samples with pathological spermiogram parameters. Andrologia 1997; 29: 77-83.
18. Zini A, de Lamirande E, Gagnon C. Reactive oxygen species in semen of infertile patients: levels of superoxide dismutase- and catalase-like activities in seminal plasma and spermatozoa. Int J Androl 1993; 16: 183-8.
19. Jeulin C, Soufir JC, Weber P, Laval-Martin D, Calvayrac R. Catalase activity in human spermatozoa and seminal plasma. Gamete Res 1989; 24: 185-96.
20. Siciliano L, Tarantino P, Longobardi F, Rago V, De Stefano C, Carpino A. Impaired seminal antioxidant capacity in human semen with hyperviscosity or oligoasthenozoospermia. J Androl 2001; 22: 798-803.
21. Zini A, Fischer MA, Mak V, Phang D, Jarvi K. Catalase-like and superoxide dismutase-like activities in human seminal plasma. Urol Res 2002; 30: 321-3.
22. Giannattasio A, De Rosa M, Smeraglia R, Zarrilli S, Cimmino A, Di Rosario B, et al. Glutathione peroxidase (GPX) activity in seminal plasma of healthy and infertile males. J Endocrinol Invest 2002; 25: 983-6.
23. Alvarez JG, Storey BT. Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility. Biol Reprod 1983; 29: 548-55.
24. Holmes RP, Goodman HO, Shihabi ZK, Jarow JP. The taurine and hypotaurine content of human semen. J Androl 1992; 13: 289-92.
25. Ostermeier GC, Dix DJ, Miller D, Khatri P, Krawetz SA. Spermatozoal RNA profiles of normal fertile men. Lancet 2002; 360: 772-7.
26. Alvarez JG, Touchstone JC, Blasco L, Storey BT. Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity. J Androl 1987; 8: 338-48.
27. de Lamirande E, Gagnon C. Impact of reactive oxygen species on spermatozoa: a balancing act between beneficial and detrimental effects. Hum Reprod 1995; 10: 15-21.
28. Aitken RJ, Paterson M, Fisher H, Buckingham DW, van Duin M. Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function. J Cell Sci 1995; 108: 2017-25.
29. Yeung CH, Cooper TG, De Geyter M, De Geyter C, Rolf C, Kamischke A, et al. Studies on the origin of redox enzymes in seminal plasma and their relationship with results of in- vitro fertilization. Mol Hum Reprod 1998; 4: 835-9.
30. Hendin BN, Kolettis PN, Sharma RK, Thomas AJ Jr, Agarwal A. Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity. J Urol 1999; 161: 1831-4.
31. Alkan I, Simsek F, Haklar G, Kervancioglu E, Ozveri H, Yalcin S, et al. Reactive oxygen species production by the spermatozoa of patients with idiopathic infertility: relationship to seminal plasma antioxidants. J Urol 1997; 157: 140-3.
32. Nakamura H, Kimura T, Nakajima A, Shimoya K, Takemura M, Hashimoto K, et al. Detection of oxidative stress in seminal plasma and fractionated sperm from subfertile male patients. Eur J Obstet Gynecol Reprod Biol 2002; 105: 155-60.
33. Agarwal A, Saleh RA. Role of oxidants in male infertility: rationale, significance, and treatment. Urol Clin North Am 2002; 29: 817-27.
34. Sharma RK, Pasqualotto FF, Nelson DR, Thomas AJ Jr, Agarwal A. The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility. Hum Reprod 1999; 14: 2801-7.