Oligodendrocytes damage in Alzheimer's disease: Beta amyloid toxicity and inflammation

Biological Research

Volumn 38, Issue 4, 2005, Pages 381-387

  Roth, Alejandro D ^a,b   Ramírez, Gigliola ^a   Alarcón, Rodrigo ^a   Von Bernhardi, Rommy ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Cell death; Glial cells; Pro inflammatory cytokines

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA INTERFERON; LIPOPOLYSACCHARIDE;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL CULTURE; CELL DAMAGE; CELL PROTECTION; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; EXPERIMENTAL DESIGN; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; INFLAMMATION; METABOLIC ACTIVATION; MICROGLIA; MODULATION; MYELINATION; NEUROPATHOLOGY; OLIGODENDROGLIA; OXIDATIVE STRESS; WHITE MATTER;

EID: 33646050649     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602005000400011     Document Type: Article

References (58)

1. BACK SA, GAN X, LI Y, ROSEMBERG PA, VOLPE JJ (1998) Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion. J Neurosci 18: 6241-6253
2. BARTZOKIS G, CUMMINGS JL, SULTZER D, ENDERSON VW, NEUCHTERLEIN KH, MINTZ J (2003) White matter structural integrity in healthy aging adults and patients with Alzheimer's disease: A magnetic resonance imaging study. Arch Neurol 60: 393-398
3. BARTZOKIS G (2004) Age-related myelin breakdown: A developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging 25: 5-18
4. BARTZOKIS G, SULTZER D, LU PH, NEUCHTERLEIN KH, MINTZ J CUMMINGS JL (2004) Heterogeneous age-related breakdown of white matter structural integrity: Implications for cortical "disconnection" in aging and Alzheimer's disease. Neurobiol Aging 25: 843-851
5. BRAAK H, BRAAK E (1996) Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis. Acta Neuropathol (Berl) 92: 197-201
6. BRAAK H, DEL TREDICI K, SCHULTZ C, BRAAK E (2000) Vulnerability of select neuronal types to Alzheimer's disease. Ann NY Acad Sci 924: 53-61
7. BROWN WR, MOODY DM, THORE CR, CHALLA VR (2000) Cerebrovascular pathology in Alzheimer's disease and leukoaraiosis. Ann NY Acad Sci 903: 39-45
8. CAMMER W (2000) Effects of TNFα on immature and mature oligodendrocytes and their progenitors in vitro. Brain Research 864: 213-219
9. +2 homeostasis in health and disease. Biol Res 37: 653-660
10. 135-156 modulates copper induced neurotoxicity in vivo. Memory, morphology, oxidative stress and uptake of copper. Biol Res 36: R-31
11. COURT F, ÁLVAREZ J (2005) Local regulation of the axonal phenotype, a case of merotrophism. Biol Res 38: 365-374
12. CURTAIN CC, ALI F, VOLITAKIS I, CHERRY RA, NORTON RS, BEYREUTHER K, BARROW CJ, MASTERS CL, BUSH AI, BARNHAM KJ (2001) Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. J Biol Chem 276: 20466-20473
13. DAI X, LERCHER LD, CLINTON PM, DU Y, LIVINGSTON D, VIEIRA C, YANG L, SHEN MM, DREYFUS CF (2003) Trophic role of oligodendrocytes in the basal forebrain. J Neurosci 23: 5846-5853
14. DECARLI C (2004) Vascular factors in dementia: An overview. J Neurol Sci. 226: 19-23
15. DE LA MONTE SM (1989) Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer's disease. Ann Neurol 25: 450-459
16. DE LEEUW F-E, BARKHOF F, SCHELTENS P (2004) White matter lesions and hippocampal atrophy in Alzheimer's disease. Neurology 62: 310-312
17. DU YL, DREYFUSS CF (2002) Oligodendrocytes as providers of growth factors. J Neurosci Res 68: 647-654
18. ENGLUND E, BRUN A, AILING C (1988) White matter changes in dementia of Alzheimer's type. Brain 111: 1425-1439
19. HERRERA-MOLINA R, VON BERNHARDI R (2005) Transforming growth factor-β1 produced by hippocampal cells modulates microglial reactivity in culture. Neurobiol Disease 19: 229-236
20. IWATSUBO T, ODAKA A, SUZUKI N, MIZUSAWA H, NUKINA N, IHARA Y (1994) Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific Abeta monoclonals: Evidence that an initially deposited species is A beta 42 (43). Neuron 13: 45-53
21. JANTARATNOTAI N, RYU JK, KIM SU, MCLARNON JG (2003) Amyloid β peptide-induced corpus callosum damage and glial activation in vivo. NeuroReport 14: 1429-1433
22. JUURLINK BH, THORBURNE SK, HERTZ L (1998) Peroxide-scavenging deficit underlies oligodendrocytes susceptibility to oxidative stress. Glia 22: 371-378
23. KIURU S, SALONEN O, HALTIA M (1999) Gelsolin-related spinal and cerebral amyloid angiopathy. Ann Neurol 45: 305-311
24. KOBAYASHI K, HAYASHI M, NAKANO H, FUKUTANI Y, SASAKI K, SHIMAZAKI M, KOSHINO Y (2002) Apoptosis of astrocytes with enhanced lysosomal activity and oligodendrocytes in white matter lesions in Alzheimer's disease. Neuropathol Appl Neurobiol 28: 238-251
25. LAZO O, SINGH AK, SINGH I (1991) Postnatal development and isolation of peroxisomes from brain. J Neurochem 56: 1343-53
26. LEE J-T, XU J, LEE J-M, KU G, HAN X, YANG D-I, CHEN S, HSU CY (2004) Amyloid-β peptide induces oligodendrocytes death by activating the neutral sphingomyelinase-ceramide pathway. J Cell Biol 164: 123-131
27. LEYTON L, QUEST AF (2004) Supramolecular complex formation in cell signaling and disease: An update on a current theme in cell life and death. Biol Res 37: 29-43
28. LORENZO A (2004) The neuronal dystrophy induced by the amyloid-β-peptide (Aβ) and its modulator agents. Biol Res 37: R-12
29. MCCARTHY KD, DE VELLIS J (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85: 890-902
30. MALONE MJ, SZOKE MC (1985) Neurochemical changes in white matter. Aged human brain and Alzheimer's disease. Arch Neurol 42: 1063-1066
31. MERRILL JE, IGNARRO LJ, SHERMAN MP, MELINEK J, LANE TE (1993) Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 151: 2132-2141
32. MINN A, GHERSI-EGEA JF, PERRIN R, LEININGER B, SIEST G (1991) Drug metabolizing enzymes in the brain and cerebral micro vessels. Brain Res Brain Res Rev 16: 65-82
33. NIELSEN K, PETERS A (2000) The effects of aging on the frequency of nerve fibers in rhesus monkey striate cortex. Neurobiol Aging 21: 621-628
34. NOBLE M (2004) The possible role of myelin destruction as a precipitating event in Alzheimer's disease. Neurobiol Aging 25: 25-31
35. NOBLE M, MAYER-PRÖSCHEL M (1998) Culture of astrocytes, oligodendrocytes and O-2 progenitor cells. In: BANKER G, GOSLIN K (ed) Culturing Nerve Cells. Cambridge, London: Bradford Book. pp: 499-544
36. POPOVIC N, SCHUBART A, GOETZ BD, ZHANG SC, LININGTON C, DUNCAN ID (2002) Inhibition of autoimmune encephalomyelitis by a tetracycline. Ann Neurol 51: 215-223
37. POWER J, MAYER-PROSCHEL M, SMITH J, NOBLE M (2002) Oligodendrocytes precursor cells from different brain regions express divergent properties consistent with the differing time courses of myelination in these regions. Dev Biol 245: 362-375
38. RAMÍREZ G, TORO R, DÖBELI H, VON BERNHARDI R (2005) Protection of rat primary hippocampal cultures from Aβ cytotoxicity by pro-inflammatory molecules is mediated by astrocytes. Neurobiol Disease 19: 243-254
39. RIEK R, GUNTERT P, DOBELI H, WIPF B, WUTHRICH K (2001) NMR studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two Alzheimer peptides with widely different plaque-competence, A beta(1-40)(ox) and A beta(1-42)(ox). Eur J Biochem 268: 5930-6
40. ROHER AE, WEISS N, KOKJOHN TA, KUO YM, KALBACK W, ANTHONY J, WATSON D, LUEHRS DC, SUE L, WALKER D, EMMERLING M, GOUX W, BEACH T (2002) Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease. Biochemistry 41: 11080-11090
41. SELKOE DJ (2004) Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases. Nat Cell Biol 6: 1054-61
42. SEVENNERHOLM L, GOTTFRIES CG (1994) Membrane lipids, selectively diminished in Alzheimer brains, suggests synapse loss as a primary event in early-onset form (type I) and demyelination in later-onset from (type II). J Neurochem 62: 1039-1047
43. SMITH KJ, KAPOOR R, FELTS PA (1999) Demyelination: The role of reactive oxygen and nitrogen species. Brain Pathol 9: 69-92
44. SUBASINGHE S, UNABIA S, BARROW CJ, MOK SS, AGUILAR MI, SMALL DH (2003) Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes. J Neurochem 84: 471-9
45. TANAKA F, KACHI T, YAMADA T, SOBUE G (1994) Auditory and visual event-related potentials and flash visual evoked potentials in Alzheimer's disease: Correlations with Mini-Mental State examination and Raven's coloured progressive matrices. J Neurol Sci 156: 83-88
46. THOMAS T, THOMAS G, MCLENDON C, SYTTON T, MULLAN M (1996) Beta-amyloid-mediated vasoactivity and vascular endothelial damage. Nature 380: 168-171
47. UMAHARA T, TSUCHIYA K, IKEDA K, KANAYA K, IWAMOTO T, TAKASAKI M, MUKAI K, SHIBATA N, KATO S (2002) Demonstration and distribution of tau-positive glial coiled body-like structures in white matter and white matter threads in early onset Alzheimer's disease. Neuropathology 22: 9-12
48. VERMEER SE, PRINS ND, DEN HEIJER T, HOFMAN A, KOUDSTAAL PJ, BRETELER MMB (2003) Silent brain infarcts and the risk of dementia and cognitive decline. N England J Med 348: 1215-1222
49. VOLPE JJ (1998) Brain injury in the premature infant: Overview of clinical aspects, neuropathology, and pathogenesis. Semin Pediatr Neurol 5: 135-151
50. VON BERNHARDI R, RAMÍREZ G (2001) Microglia-astrocyte interaction in Alzheimer's disease: Friends or foes for the nervous system? Biol Res 34: 123-128
51. VON BERNHARDI R, EUGENÍN J (2004) Microglial reactivity to Aβ is modulated by astrocytes and proinflammatory factors. Brain Res 1025: 186-193
52. WIESNIEWSKI HM, BANCHER C, BARCIKOWSKA M, WEN GY, CURRIE J (1989) Spectrum of morphological appearance of amyloid deposits in Alzheimer's disease. Acta Neuropathol (Berl) 78: 337-347
53. WILSON JX (1997) Antioxidant defense of the brain: A role for astrocytes. Can J Physiol Pharmacol 75: 1149-63
54. WHITMAN GT, COTMAN CW (2004) Oligodendrocyte degeneration in AD. Neurobiol Aging 25: 33-6
55. XIE Z, WIE M, MORGAN TE, FABRIZIO P, HAN D, FINCH CE, LONGO VD (2002) Peroxynitrite mediates neurotoxicity of amyloid beta-peptide 1 -42- and lipopolysaccharide-activated microglia. J Neurosci 22: 3484-3492
56. XU J, YEH CH. YEN S, HE L, SENSI SL, CANZONIERO LM, CHOI DW, HSU CY (1998) Involvement of de novo ceramide biosynthesis in tumor necrosis factoralpha/cycloheximide-induced cerebral endothelium cell death. J Biol Chem 273: 16521-16526
57. XU J, CHEN S, AHMED SH, CHEN H, KU G, GOLDBERG MP, HSU CY (2001) Amyloid-b peptides are cytotoxic to oligodendrocytes. J Neurosci 21: RC118 (1-5)
58. YANKNER BA, DAWES LR, FISHER S, VILLA-KOMAROFF I, OSTER-GRANITE ML, NEVE RI (1989) Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science 245: 417-420