Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: Riboregulation against neural oxidative damage in Alzheimer's disease

Biochemical Society Transactions

Volumn 36, Issue 6, 2008, Pages 1282-1287

  Rogers, Jack T ^a   Bush, Ashley I ^b   Cho, Hyan Hee ^a   Smith, Deborah H ^c   Thomson, Andrew M ^d   Friedrlich, Avi L ^a   Lahiri, Debomoy K ^e   Leedman, Peter J ^f   Huang, Xudong ^a,g   Cahill, Catherine M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GENOME INSTITUTE OF SINGAPORE   (Singapore)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Amyloid precursor protein (APP); Copper; Ferritin; Iron; Oxidative stress; Zinc

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; COPPER ION; CYTOKINE; FERRITIN; INTERLEUKIN 1; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; MESSENGER RNA; RNA BINDING PROTEIN; TRANSFERRIN RECEPTOR; ZINC ION;

5' UNTRANSLATED REGION; ALZHEIMER DISEASE; ARTICLE; BRAIN CORTEX; CATALYSIS; GENETIC LINKAGE; HOMEOSTASIS; HUMAN; IRON RESPONSIVE ELEMENT; NERVE CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; REGULATORY MECHANISM; REPERFUSION; RNA STABILITY; STROKE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; FERRITINS; HUMANS; IRON; NEURONS; OXIDATIVE STRESS; PROTEIN BIOSYNTHESIS;

EID: 59149101704     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0361282     Document Type: Article

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