β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

Journal of Neuroscience

Volumn 24, Issue 2, 2004, Pages 565-575

  Abramov, Andrey Y ^a   Canevari, Laura ^b   Duchen, Michael R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Alzheimer; Astrocyte; Astroglia; Calcium; Mitochondria; NADPH; Neuron

Indexed keywords

ACETOPHENONE DERIVATIVE; AMYLOID BETA PROTEIN; CALCIUM; DIPHENYLIODONIUM SALT; GLUTAMIC ACID; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN MITOCHONDRION; CELL MEMBRANE DEPOLARIZATION; CELL VIABILITY; CONTROLLED STUDY; MACROGLIA; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; RESPIRATORY CHAIN;

EID: 1642499152     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4042-03.2004     Document Type: Article

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