Age-related loss of phospholipid asymmetry in APPNLh/APPNLh x PS-1P264L/PS-1P264L human double mutant knock-in mice: Relevance to Alzheimer disease

Neurobiology of Disease

Volumn 38, Issue 1, 2010, Pages 104-115

  Bader Lange, Miranda L ^a   St Clair, Daret ^a   Markesbery, William R ^b   Studzinski, Christa M ^b   Murphy, M Paul ^b   Butterfield, D Allan ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Amyloid precursor protein (APP); Apoptosis; Caspase 3; Familial Alzheimer disease (FAD); Lipid peroxidation; Oxidative stress; Phosphatidylserine (PtdSer); Phospholipid asymmetry; Presenilin 1 (PS 1); Toxic A (1 42) oligomers

Indexed keywords

ADENOSINE TRIPHOSPHATASE (MAGNESIUM); AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CARRIER PROTEIN; CASPASE 3; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PRESENILIN 1;

AGE; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; ENZYME DEGRADATION; FAMILIAL DISEASE; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SYNAPTOSOME; WILD TYPE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANNEXIN A5; APOPTOSIS; BRAIN; BRAIN CHEMISTRY; CASPASE 3; DISEASE MODELS, ANIMAL; GENE KNOCK-IN TECHNIQUES; HUMANS; LIPID METABOLISM; MICE; MICE, TRANSGENIC; NERVE DEGENERATION; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; PHOSPHATIDYLSERINES; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHOLIPIDS; PRESENILIN-1; SYNAPTOSOMES;

EID: 77549087405     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.01.004     Document Type: Article

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