Degradation of soluble and fibrillar amyloid β-protein by matrix metalloproteinase (MT1-MMP) in vitro

Biochemistry

Volumn 49, Issue 6, 2010, Pages 1127-1136

  Liao, Mei Chen ^a   Van Nostrand, William E ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; AMYLOID DEPOSITS; AMYLOID PLAQUES; CELL EXPRESSION; CLEAVAGE SITES; DEGRADATION PRODUCTS; DEGRADING ACTIVITIES; IN-SITU EXPERIMENTS; IN-VITRO; MASS SPECTROMETRY ANALYSIS; MATRIX METALLOPROTEINASE-2; MATRIX METALLOPROTEINASES; MEMBRANE TYPES; MMP INHIBITOR; PRECURSOR PROTEINS; PROGRESSIVE ACCUMULATION; PROTEOLYTIC ENZYME; SENILE PLAQUES; TIME-DEPENDENT; TISSUE INHIBITOR OF METALLOPROTEINASES-2; TRANSGENIC MICE; VASCULATURE;

BLOOD VESSELS; GENE EXPRESSION; GLYCOPROTEINS; MASS SPECTROMETRY; PROTEINS; PURIFICATION; ULSI CIRCUITS;

DEGRADATION;

AMYLOID BETA PROTEIN; ILOMASTAT; MATRIX METALLOPROTEINASE 14; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL STRAIN COS1; ENZYME ACTIVITY; ENZYME ANALYSIS; IN VITRO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ASTROCYTES; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE MODELS, ANIMAL; HUMANS; HYDROLYSIS; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NEUROFIBRILLARY TANGLES; PEPTIDE FRAGMENTS; SOLUBILITY;

MUS MUSCULUS;

EID: 76749099393     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901994d     Document Type: Article

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