메뉴 건너뛰기




Volumn 12, Issue SUPPL. 2, 1998, Pages

Interfering with the pathologic activation of microglial cells and astrocytes in dementia

Author keywords

Adenosine; Ca2+; Cyclic nucleotides; Dementia; Endogenous modulator; Glial cell modulator; Homeostatic regulation; Intracellular signaling; Neuroprotection; Propentofylline; Second messengers

Indexed keywords

ADENOSINE; AMYLOID BETA PROTEIN; CALCIUM ION; CYCLIC AMP; CYTOKINE; GLUTAMIC ACID; INTERLEUKIN 1BETA; NEUROTROPHIC FACTOR; NITRIC OXIDE; OXYGEN RADICAL; PEROXYNITRITE; PHOSPHODIESTERASE; POTASSIUM ION; PROPENTOFYLLINE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 0032460149     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (38)

References (44)
  • 1
    • 0024498291 scopus 로고
    • Alzheimer's disease: Recent advances in understanding the brain amyloid deposits
    • Abraham CA, Potter H. Alzheimer's disease: recent advances in understanding the brain amyloid deposits. Biotechnology 1989;7:147-53.
    • (1989) Biotechnology , vol.7 , pp. 147-153
    • Abraham, C.A.1    Potter, H.2
  • 2
    • 0026602079 scopus 로고
    • β-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease
    • Araujo DM, Cotman CW. β-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease. Brain Res 1992;569:141-5.
    • (1992) Brain Res , vol.569 , pp. 141-145
    • Araujo, D.M.1    Cotman, C.W.2
  • 3
    • 0028118593 scopus 로고
    • Modulation of intracellular reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by propentofylline
    • Banati R, Schubert P, Rothe G, Gehrmann J, Rudolphi K, Valet G, Kreutzberg GW. Modulation of intracellular reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by propentofylline. J Cereb Blood Flow Metab 1994;14: 145-9.
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 145-149
    • Banati, R.1    Schubert, P.2    Rothe, G.3    Gehrmann, J.4    Rudolphi, K.5    Valet, G.6    Kreutzberg, G.W.7
  • 4
    • 0345001706 scopus 로고    scopus 로고
    • Alzheimer's disease: Does intracellular transport hold the key?
    • Dementia Issue
    • Beyreuther K, Masters C. Alzheimer's disease: does intracellular transport hold the key? The News [Dementia Issue] 1997;3:2-4.
    • (1997) The News , vol.3 , pp. 2-4
    • Beyreuther, K.1    Masters, C.2
  • 5
    • 0030589145 scopus 로고    scopus 로고
    • Human APOE protein localized in brains of transgenic mice
    • Bowman BH, Yang F, Buchanan JM, et al. Human APOE protein localized in brains of transgenic mice. Neurosci Lett 1996;219:57-9.
    • (1996) Neurosci Lett , vol.219 , pp. 57-59
    • Bowman, B.H.1    Yang, F.2    Buchanan, J.M.3
  • 6
    • 0028207004 scopus 로고
    • Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner
    • Buxbaum JD, Ruefli AA, Parker CA, Cypess AM, Greengard P. Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. Proc Natl Acad Sci USA 1994;91:4489-93.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4489-4493
    • Buxbaum, J.D.1    Ruefli, A.A.2    Parker, C.A.3    Cypess, A.M.4    Greengard, P.5
  • 7
    • 0028889206 scopus 로고
    • Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1
    • Das S, Potter H. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron 1995;14:447-56.
    • (1995) Neuron , vol.14 , pp. 447-456
    • Das, S.1    Potter, H.2
  • 8
    • 0023549563 scopus 로고
    • Ischemia-induced neuronal cell death, calcium accumulation and glial response in the hippocampus of the gerbil and protection by the xanthine derivative HWA 285
    • DeLeo J, Tóth L, Schubert P, Rudolphi K, Kreutzberg GW. Ischemia-induced neuronal cell death, calcium accumulation and glial response in the hippocampus of the gerbil and protection by the xanthine derivative HWA 285. J Cereb Blood Flow Metab 1987; 7:745-52.
    • (1987) J Cereb Blood Flow Metab , vol.7 , pp. 745-752
    • Deleo, J.1    Tóth, L.2    Schubert, P.3    Rudolphi, K.4    Kreutzberg, G.W.5
  • 10
    • 0029047781 scopus 로고
    • Two distinct inward rectifying conductances are expressed in cultured rat cortical astrocytes after long term dibutyryl-cyclic-AMP treatment
    • Ferroni S, Marchini C, Schubert P, Rapisarda C. Two distinct inward rectifying conductances are expressed in cultured rat cortical astrocytes after long term dibutyryl-cyclic-AMP treatment. FEBS Lett 1995;267:319-25.
    • (1995) FEBS Lett , vol.267 , pp. 319-325
    • Ferroni, S.1    Marchini, C.2    Schubert, P.3    Rapisarda, C.4
  • 11
    • 0030268068 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors
    • Fiebich BL, Biber K, Lieb K, et al. Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors. Glia 1996;18: 152-60.
    • (1996) Glia , vol.18 , pp. 152-160
    • Fiebich, B.L.1    Biber, K.2    Lieb, K.3
  • 12
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor
    • Fischer W, Wictorin K, Björklund A, Williams LR, Varon S, Cage FH. Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature 1987;329: 65-8.
    • (1987) Nature , vol.329 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Björklund, A.3    Williams, L.R.4    Varon, S.5    Cage, F.H.6
  • 13
    • 0026452028 scopus 로고
    • Expression of amyloid precursor protein mRNA in endothelial, neuronal and glial cells: Modulation by interleukin-1
    • Forloni G, Demicheli F, Giorgi S, Bendotti C, Angeretti N. Expression of amyloid precursor protein mRNA in endothelial, neuronal and glial cells: modulation by interleukin-1. Mol Brain Res 1992;16: 128-34.
    • (1992) Mol Brain Res , vol.16 , pp. 128-134
    • Forloni, G.1    Demicheli, F.2    Giorgi, S.3    Bendotti, C.4    Angeretti, N.5
  • 15
    • 0023614999 scopus 로고
    • Ameboid microglia as effector of inflammation in the central nervous system
    • Giulian D. Ameboid microglia as effector of inflammation in the central nervous system. J Neurosci Res 1987;18:155-71.
    • (1987) J Neurosci Res , vol.18 , pp. 155-171
    • Giulian, D.1
  • 16
    • 0025043211 scopus 로고
    • Cultured microglia have a distinct pattern of membrane channels different from peritoneal macrophages
    • Kettenmann H, Hoppe D, Gottmann K, Banati R, Kreutzberg G. Cultured microglia have a distinct pattern of membrane channels different from peritoneal macrophages. J Neurosci Res 1990;26:278-87.
    • (1990) J Neurosci Res , vol.26 , pp. 278-287
    • Kettenmann, H.1    Hoppe, D.2    Gottmann, K.3    Banati, R.4    Kreutzberg, G.5
  • 17
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurol Sci 1996;19:312-8.
    • (1996) Trends Neurol Sci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 18
    • 0028173205 scopus 로고
    • Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of beta-protein into filaments
    • Ma J, Yee A, Brewer HB, Das S, Potter H. Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of beta-protein into filaments. Nature 1994;372:92-4.
    • (1994) Nature , vol.372 , pp. 92-94
    • Ma, J.1    Yee, A.2    Brewer, H.B.3    Das, S.4    Potter, H.5
  • 19
    • 0026487634 scopus 로고
    • Synthesis and release of neuroactive substances by glial cells
    • Martin DL. Synthesis and release of neuroactive substances by glial cells. Glia 1992;5:81-94.
    • (1992) Glia , vol.5 , pp. 81-94
    • Martin, D.L.1
  • 20
    • 0026570528 scopus 로고
    • β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson MP, Cheng B, Davis D, Bryant K, Leieberburg I, Rydel R. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992;12:376-89.
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Leieberburg, I.5    Rydel, R.6
  • 22
    • 0028244558 scopus 로고
    • Propentofylline depresses amyloid and Alzheimer's CSF microglial antigens after ischemia
    • McRae A, Rudolphi K, Schubert P. Propentofylline depresses amyloid and Alzheimer's CSF microglial antigens after ischemia. Neuroreport 1994;5:1193-6.
    • (1994) Neuroreport , vol.5 , pp. 1193-1196
    • McRae, A.1    Rudolphi, K.2    Schubert, P.3
  • 23
    • 0028953529 scopus 로고
    • Activation of microglial cells by β-amyloid protein and interferon-γ
    • Meda L, Cassatella MA, Szendrei I. Activation of microglial cells by β-amyloid protein and interferon-γ. Nature 1995;374:647-50.
    • (1995) Nature , vol.374 , pp. 647-650
    • Meda, L.1    Cassatella, M.A.2    Szendrei, I.3
  • 24
    • 0028348063 scopus 로고
    • Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation
    • Meskini N, Némoz G, Okyayuz-Baklouti I, Lagard M, Prigent AF. Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation. Biochem Pharmacol 1994;47:781-8.
    • (1994) Biochem Pharmacol , vol.47 , pp. 781-788
    • Meskini, N.1    Némoz, G.2    Okyayuz-Baklouti, I.3    Lagard, M.4    Prigent, A.F.5
  • 25
    • 0345001698 scopus 로고    scopus 로고
    • Inhibitory effects of adenosine agonists and propentofylline on the proliferation and transformation of cultured microglia
    • Okada Y, ed. Amsterdam, New York, Tokyo: Elsevier
    • Nakamura Y, Si QS, Kataoka K, Ogata T, Schubert P. Inhibitory effects of adenosine agonists and propentofylline on the proliferation and transformation of cultured microglia. In: Okada Y, ed. The role of adenosine in the nervous system. Amsterdam, New York, Tokyo: Elsevier, 1997:97-102.
    • (1997) The Role of Adenosine in the Nervous System , pp. 97-102
    • Nakamura, Y.1    Si, Q.S.2    Kataoka, K.3    Ogata, T.4    Schubert, P.5
  • 26
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka Y. Studies and perspectives of protein kinase C. Science 1986;233:305-12.
    • (1986) Science , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 28
    • 0028278611 scopus 로고
    • 2+ mobilization in conjunction with metabotropic glutamate receptor activation by t-ACPD in cultured hippocampal astrocytes
    • 2+ mobilization in conjunction with metabotropic glutamate receptor activation by t-ACPD in cultured hippocampal astrocytes. Neurosci Lett 1994;170:5-8.
    • (1994) Neurosci Lett , vol.170 , pp. 5-8
    • Ogata, T.1    Nakamura, Y.2    Tsuji, K.3    Shibata, T.4    Kataoka, K.5    Schubert, P.6
  • 29
    • 0030296271 scopus 로고    scopus 로고
    • Programmed cell death in rat microglia is controlled by extracellular adenosine
    • Ogata T, Schubert P. Programmed cell death in rat microglia is controlled by extracellular adenosine. Neurosci Lett 1996;218:91-4.
    • (1996) Neurosci Lett , vol.218 , pp. 91-94
    • Ogata, T.1    Schubert, P.2
  • 30
    • 0028326247 scopus 로고
    • G-protein coupled signal transduction systems in the Alzheimer's disease brain
    • O'Neill C, Fowler CJ, Winblad B, Cowburn RF. G-protein coupled signal transduction systems in the Alzheimer's disease brain. Biochem Soc Trans 1994;22:167-71.
    • (1994) Biochem Soc Trans , vol.22 , pp. 167-171
    • O'Neill, C.1    Fowler, C.J.2    Winblad, B.3    Cowburn, R.F.4
  • 31
    • 0025895767 scopus 로고
    • 2 receptors and nitrobenzylthioinosine-sensitive nucleoside transporters: Quantitative autoradiographic analysis
    • 2 receptors and nitrobenzylthioinosine-sensitive nucleoside transporters: quantitative autoradiographic analysis. Eur J Pharmacol 1991;202:361-6.
    • (1991) Eur J Pharmacol , vol.202 , pp. 361-366
    • Parkinson, F.E.1    Fredholm, B.B.2
  • 32
    • 0015504388 scopus 로고
    • Neuroplasmic transport in dendrites: Effect of colchicine on morphology and physiology of motoneurons in the cat
    • Schubert P, Kreutzberg GW, Lux HD. Neuroplasmic transport in dendrites: effect of colchicine on morphology and physiology of motoneurons in the cat. Brain Res 1972;47:331-43.
    • (1972) Brain Res , vol.47 , pp. 331-343
    • Schubert, P.1    Kreutzberg, G.W.2    Lux, H.D.3
  • 33
    • 0344139169 scopus 로고    scopus 로고
    • Depression of TNF-α release from microglial cells by adenosine and propentofylline
    • Schubert P, Ogata T, Rudolphi K. Depression of TNF-α release from microglial cells by adenosine and propentofylline. J Cereb Blood Flow Cell Metab 1997a;17(suppl 1):S718.
    • (1997) J Cereb Blood Flow Cell Metab , vol.17 , Issue.SUPPL. 1
    • Schubert, P.1    Ogata, T.2    Rudolphi, K.3
  • 34
    • 0030725599 scopus 로고    scopus 로고
    • Support of homeostatic glial cell signalling: A novel therapeutic approach by propentofylline
    • Schubert P, Ogata T, Rudolphi K, Marchini C, McRae A. Support of homeostatic glial cell signalling: a novel therapeutic approach by propentofylline. Ann NY Acad Sci 1997b;826:337-47.
    • (1997) Ann NY Acad Sci , vol.826 , pp. 337-347
    • Schubert, P.1    Ogata, T.2    Rudolphi, K.3    Marchini, C.4    McRae, A.5
  • 35
    • 0028172835 scopus 로고
    • Modulation of nerve and glial cell function by adenosine - Role in the development of ischemic brain damage
    • Schubert P, Rudolphi K, Fredholm F, Nakamura Y. Modulation of nerve and glial cell function by adenosine - role in the development of ischemic brain damage. Int J Biochem 1994;26:1227-36.
    • (1994) Int J Biochem , vol.26 , pp. 1227-1236
    • Schubert, P.1    Rudolphi, K.2    Fredholm, F.3    Nakamura, Y.4
  • 36
    • 0029757510 scopus 로고    scopus 로고
    • Apolipoprotein E distribution among different plaque types in Alzheimer's disease: Implications for its role in plaque progression
    • Sheng JG, Mrak RE, Griffin WS. Apolipoprotein E distribution among different plaque types in Alzheimer's disease: implications for its role in plaque progression. Neuropathol Appl Neurobiol 1996;22: 334-41.
    • (1996) Neuropathol Appl Neurobiol , vol.22 , pp. 334-341
    • Sheng, J.G.1    Mrak, R.E.2    Griffin, W.S.3
  • 37
    • 0025350664 scopus 로고
    • Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells
    • Shinoda J, Furukawa Y, Furukawa S. Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells. Biochem Pharmacol 1990;39:1813-6.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1813-1816
    • Shinoda, J.1    Furukawa, Y.2    Furukawa, S.3
  • 38
    • 0030007344 scopus 로고    scopus 로고
    • Adenosine and propentofylline inhibit phorbol ester-induced proliferation of cultured microglia
    • Si Q, Nakamura Y, Schubert P, Rudolphi K, Kataoka K. Adenosine and propentofylline inhibit phorbol ester-induced proliferation of cultured microglia. Exp Neurol 1996;137:345-9.
    • (1996) Exp Neurol , vol.137 , pp. 345-349
    • Si, Q.1    Nakamura, Y.2    Schubert, P.3    Rudolphi, K.4    Kataoka, K.5
  • 39
    • 0028577208 scopus 로고
    • Immunohistochemical evidence for apoptosis in Alzheimer's disease
    • Su JH, Anderson AJ, Cummings BJ, Cotman CW. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 1994;5:2529-33.
    • (1994) Neuroreport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.J.3    Cotman, C.W.4
  • 40
    • 0029868452 scopus 로고    scopus 로고
    • Peroxynitrite inhibits glutamate transporter subtypes
    • Trotti D, Rossi D, Gjesdal O, et al. Peroxynitrite inhibits glutamate transporter subtypes. J Biol Chem 1996;271:5976-9.
    • (1996) J Biol Chem , vol.271 , pp. 5976-5979
    • Trotti, D.1    Rossi, D.2    Gjesdal, O.3
  • 41
    • 0018634064 scopus 로고
    • Adenosine regulates via different types of receptors the accumulation of cyclic AMP in cultured brain cells
    • van Calker D, Müller M, Hamprecht G. Adenosine regulates via different types of receptors the accumulation of cyclic AMP in cultured brain cells. J Neurochem 1979;33:999-1005.
    • (1979) J Neurochem , vol.33 , pp. 999-1005
    • Van Calker, D.1    Müller, M.2    Hamprecht, G.3
  • 42
    • 0028226885 scopus 로고
    • Astroglial differentiation is required for support of neunte outgrowth
    • Wang C, Baird DH, Hatten ME, Mason CA. Astroglial differentiation is required for support of neunte outgrowth. J Neurosci 1994;14: 3195-207.
    • (1994) J Neurosci , vol.14 , pp. 3195-3207
    • Wang, C.1    Baird, D.H.2    Hatten, M.E.3    Mason, C.A.4
  • 44
    • 0026542786 scopus 로고
    • Apolipoprotein E: A pathological chaperone in patients with cerebral and systemic amyloid
    • Wisniewsky T, Frangione B. Apolipoprotein E: a pathological chaperone in patients with cerebral and systemic amyloid. Neurosci Lett 1992;135:235-8.
    • (1992) Neurosci Lett , vol.135 , pp. 235-238
    • Wisniewsky, T.1    Frangione, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.