From aging to Alzheimer's disease: Unveiling "The switch" with the senescence-accelerated mouse model (SAMP8)

Journal of Alzheimer's Disease

Volumn 15, Issue 4, 2008, Pages 615-624

  Pallas, Merce ^a   Camins, Antoni ^a   Smith, Mark A ^b   Perry, George ^b,c   Lee, Hyoung Gon ^b   Casadesus, Gemma ^b,d  

^a UNIVERSITY OF BARCELONA   (Spain)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c University of San Antonio   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Alzheimer's disease; Amyloid ; Animal models; Cognition; Gliosis; Neurodegeneration; Oxidative stress; SAMP8; Tau phosphorylation

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; GLIAL FIBRILLARY ACIDIC PROTEIN; LITHIUM CHLORIDE; MELATONIN; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; TAU PROTEIN;

AGED; AGING; ALZHEIMER DISEASE; BEHAVIOR CHANGE; BRAIN CORTEX; CHRONOLOGY; CLINICAL FEATURE; COGNITION; COGNITIVE DEFECT; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; FAMILIAL DISEASE; GENE MUTATION; GLIOSIS; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEARNING; MAZE TEST; MEMORY; NERVE DEGENERATION; NEUROCHEMISTRY; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; SENESCENCE ACCELERATED MOUSE; SENILE PLAQUE; STATE DEPENDENT LEARNING;

EID: 58149380018     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2008-15408     Document Type: Review

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