메뉴 건너뛰기




Volumn 3, Issue 1, 2009, Pages 88-93

Oxidative stress in Alzheimer disease

Author keywords

Advanced glycation endproducts; Ageing; Alzheimer disease; Amyloid; Oxidative stress

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALPHA TOCOPHEROL; AMINOGUANIDINE; AMYLOID PROTEIN; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; DNA; FREE RADICAL; GLUCOSE; NONSTEROID ANTIINFLAMMATORY AGENT; PYRIDOXAMINE; THIOCTIC ACID;

EID: 67049134478     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.3.1.7402     Document Type: Review
Times cited : (337)

References (97)
  • 1
    • 0029657946 scopus 로고    scopus 로고
    • The neurochemistry of Alzheimer type, vascular type and mixed type dementias compared
    • Gsell W, Strein I, Riederer P. The neurochemistry of Alzheimer type, vascular type and mixed type dementias compared. J Neural Transm 1996; 47:73-101. (Pubitemid 26275591)
    • (1996) Journal of Neural Transmission, Supplement , Issue.47 , pp. 73-101
    • Gsell, W.1    Strein, I.2    Riederer, P.3
  • 2
    • 0031283226 scopus 로고    scopus 로고
    • Neurochemical abnormalities in Alzheimer's disease and Parkinson's disease - A comparative review
    • Gsell W, Strein I, Krause U, Riederer P. Neurochemical abnormalities in Alzheimer's disease and Parkinson's disease-a comparative review. J Neural Transm 1997; 51:145-159 (Pubitemid 28055697)
    • (1997) Journal of Neural Transmission, Supplement , Issue.51 , pp. 145-159
    • Gsell, W.1    Strein, I.2    Krause, U.3    Riederer, P.4
  • 14
    • 0025942074 scopus 로고
    • Age-related elevation of lipid peroxidation products: Diminution of superoxide dismutase activity in the central nervous system of rats
    • Gupta A, Hasan M, Chander R, Kapoor K. Age-related elevation of lipid peroxidation products: diminution of superoxide dismutase activity in the central nervous system of rats. Gerontology 1991; 37:305-309
    • (1991) Gerontology , vol.37 , pp. 305-309
    • Gupta, A.1    Hasan, M.2    Chander, R.3    Kapoor, K.4
  • 15
    • 0028854465 scopus 로고
    • Studies on lipid peroxidation and protein oxidation in the aging brain
    • Cini M, Moretti A. Studies on lipid peroxidation and protein oxidation in the aging brain. Neurobiol Aging 1995; 16:53-57
    • (1995) Neurobiol Aging , vol.16 , pp. 53-57
    • Cini, M.1    Moretti, A.2
  • 18
    • 0037281744 scopus 로고    scopus 로고
    • Lipoproteins and lipid peroxidation in Alzheimer's disease
    • Bassett CN, Montine TJ. Lipoproteins and lipid peroxidation in Alzheimer's disease. J Nutr Health Aging 2003; 7:24-29
    • (2003) J Nutr Health Aging , vol.7 , pp. 24-29
    • Bassett, C.N.1    Montine, T.J.2
  • 21
    • 38049010515 scopus 로고    scopus 로고
    • Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
    • Lovell MA, Markesbery WR. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res 2007; 35:7497-7504
    • (2007) Nucleic Acids Res , vol.35 , pp. 7497-7504
    • Lovell, M.A.1    Markesbery, W.R.2
  • 23
    • 0034492467 scopus 로고    scopus 로고
    • Cognitive impairment and oxidative stress in the elderly: Results of epidemiological studies
    • Berr C. Cognitive impairment and oxidative stress in the elderly: results of epidemiological studies. Biofactors 2000; 13:205-209 (Pubitemid 32107366)
    • (2000) BioFactors , vol.13 , Issue.1-4 , pp. 205-209
    • Berr, C.1
  • 24
    • 4244040278 scopus 로고    scopus 로고
    • Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: Involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors
    • DOI 10.1016/S0009-2797(97)00157-9, PII S0009279797001579
    • Thornalley PJ. Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system-involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors. Chem Biol Interactions 1998; 112:137-151 (Pubitemid 28271940)
    • (1998) Chemico-Biological Interactions , vol.111-112 , pp. 137-151
    • Thornalley, P.J.1
  • 27
    • 0035131601 scopus 로고    scopus 로고
    • Age-related changes of glutathione content, glucose transport and metabolism, and mitochondrial electron transfer function in mouse brain
    • DOI 10.1016/S0969-8051(00)00180-3, PII S0969805100001803
    • Sasaki T, Senda M, Kim S-N, Kojima S, Kubodera A. Age-related changes of glutathione content, glucose transport and metabolism, and mitochondrial electron transfer function in mouse brain. Nucl Med Biol 2001; 28:25-31. (Pubitemid 32155962)
    • (2001) Nuclear Medicine and Biology , vol.28 , Issue.1 , pp. 25-31
    • Sasaki, T.1    Senda, M.2    Kim, S.-N.3    Kojima, S.4    Kubodera, A.5
  • 28
    • 0036570038 scopus 로고    scopus 로고
    • Down-regulation of g-glutamylcysteine synthetase regulatory subunit gene expression in rat brain tissue during aging
    • DOI 10.1002/jnr.10217
    • Liu RM. Downregulation of g-glutamil cysteine synthetase regulatory subunit gene expression in rat brain tissue during aging. J Neurosci Res 2002; 68:344-351 (Pubitemid 34462540)
    • (2002) Journal of Neuroscience Research , vol.68 , Issue.3 , pp. 344-351
    • Liu, R.-M.1
  • 29
    • 0036082232 scopus 로고    scopus 로고
    • Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes
    • DOI 10.1023/A:1015643107449
    • Sandhu SK, Kaur G. Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes. Biogerontology 2002; 3:161-173 (Pubitemid 34678894)
    • (2002) Biogerontology , vol.3 , Issue.3 , pp. 161-173
    • Sandhu, S.K.1    Kaur, G.2
  • 30
    • 0037653659 scopus 로고    scopus 로고
    • Gender difference in glutathione metabolism during aging in mice
    • DOI 10.1016/S0531-5565(03)00036-6
    • Wang H, Liu H, Liu R. Gender difference in glutathione metabolism during aging in mice. Exp Gerontol 2003; 38:507-517 (Pubitemid 36549037)
    • (2003) Experimental Gerontology , vol.38 , Issue.5 , pp. 507-517
    • Wang, H.1    Liu, H.2    Liu, R.-M.3
  • 32
    • 28244472080 scopus 로고    scopus 로고
    • Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus
    • DOI 10.1016/j.mad.2005.09.003, PII S0047637405002228
    • Donahue AN, Aschner M, Lash LH, Syversen T, Sonntag WE. Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus. Mech Ageing Dev 2006; 127:57-63. (Pubitemid 41713514)
    • (2006) Mechanisms of Ageing and Development , vol.127 , Issue.1 , pp. 57-63
    • Donahue, A.N.1    Aschner, M.2    Lash, L.H.3    Syversen, T.4    Sonntag, W.E.5
  • 33
    • 33744525840 scopus 로고    scopus 로고
    • Age-related changes in glutathione and glutathione-related enzymes in rat brain
    • DOI 10.1016/j.brainres.2006.03.063, PII S0006899306008481
    • Zhu Y, Carvey PM, Ling Z. Age-related changes in glutathione and glutathione-related enzymes in rat brain. Brain Res 2006; 1090:35-44. (Pubitemid 43817938)
    • (2006) Brain Research , vol.1090 , Issue.1 , pp. 35-44
    • Zhu, Y.1    Carvey, P.M.2    Ling, Z.3
  • 34
    • 0028842244 scopus 로고
    • Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type
    • Gsell W, Conrad R, Hickethier M, Sofic E, Frölich L, Wichart I, et al. Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type. J Neurochem 1995; 64:1216-1223
    • (1995) J Neurochem , vol.64 , pp. 1216-1223
    • Gsell, W.1    Conrad, R.2    Hickethier, M.3    Sofic, E.4    Frölich, L.5    Wichart, I.6
  • 35
    • 12844278044 scopus 로고    scopus 로고
    • The oxidative environment and protein damage
    • DOI 10.1016/j.bbapap.2004.08.007, PII S1570963904002183, Mewthionine Oxidation and Methionine Sulfoxide Reductases
    • Davies MJ. The oxidative environment and protein damage. Biochim Biophys Acta 2005; 1703:93-109. (Pubitemid 40170433)
    • (2005) Biochimica et Biophysica Acta - Proteins and Proteomics , vol.1703 , Issue.2 , pp. 93-109
    • Davies, M.J.1
  • 36
    • 0030841350 scopus 로고    scopus 로고
    • Protein oxidation in aging, disease, and oxidative stress
    • DOI 10.1074/jbc.272.33.20313
    • Berlett BS, Stadtman ER. Protein oxidation in aging, disease and oxidative stress. J Biol Chem 1997; 272:20313-20316 (Pubitemid 27355575)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20313-20316
    • Berlett, B.S.1    Stadtman, E.R.2
  • 38
    • 0028291974 scopus 로고
    • Carbonyl assays for determination of oxidatively modified proteins
    • DOI 10.1016/S0076-6879(94)33040-9
    • Levine RL, Williams JA, Stadtman ER, Shacter E. Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol 1994; 233:346-357 (Pubitemid 24177560)
    • (1994) Methods in Enzymology , vol.233 , pp. 346-357
    • Levine, R.L.1    Williams, J.A.2    Stadtman, E.R.3    Shacter, E.4
  • 39
    • 0031776586 scopus 로고    scopus 로고
    • Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4- Dinitrophenylhydrazine
    • Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, et al. Cytochemical demonstration of oxidative damage in Alzheimer's disease by immunochemical enhancement of the carbonyl reaction with 2,4- dinitrophenylhydrazine. J Histochem Cytochem 1998; 46:731-735 (Pubitemid 28272207)
    • (1998) Journal of Histochemistry and Cytochemistry , vol.46 , Issue.6 , pp. 731-735
    • Smith, M.A.1    Sayre, L.M.2    Anderson, V.E.3    Harris, P.L.R.4    Beal, M.F.5    Kowall, N.6    Perry, G.7
  • 40
    • 34147221048 scopus 로고    scopus 로고
    • Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer disease
    • DOI 10.1373/clinchem.2006.078014
    • Korolainen MA, Nyman TA, Nyyssonen P, Hartikainen ES, Pirttila T. Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer's disease. Clin Chem 2007; 53:657-665 (Pubitemid 46580235)
    • (2007) Clinical Chemistry , vol.53 , Issue.4 , pp. 657-665
    • Korolainen, M.A.1    Nyman, T.A.2    Nyyssonen, P.3    Hartikainen, E.S.4    Pirttila, T.5
  • 42
    • 0029073455 scopus 로고
    • Elevated thiobarbituric acid- Reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
    • Lovell MA, Ehmann WD, Butler SM, Markesbery WR. Elevated thiobarbituric acid- reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 1995; 45:1594-1601
    • (1995) Neurology , vol.45 , pp. 1594-1601
    • Lovell, M.A.1    Ehmann, W.D.2    Butler, S.M.3    Markesbery, W.R.4
  • 43
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid b- Peptide
    • Mark RJ, Lovell MA, Markesbery WR, Uchida K, Mattson MP. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid b-peptide. J Neurochem 1997; 68:255-264 (Pubitemid 26427315)
    • (1997) Journal of Neurochemistry , vol.68 , Issue.1 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 44
    • 0031980065 scopus 로고    scopus 로고
    • Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
    • DOI 10.1016/S0197-4580(98)00009-8, PII S0197458098000098
    • Markesbery WR, Lovell MA. Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol Aging 1998; 19:33-36 (Pubitemid 28167792)
    • (1998) Neurobiology of Aging , vol.19 , Issue.1 , pp. 33-36
    • Markesbery, W.R.1    Lovell, M.A.2
  • 45
    • 0035985698 scopus 로고    scopus 로고
    • Lipid peroxidation in neurodegeneration: New insights into Alzheimer's disease
    • DOI 10.1097/00041433-200206000-00009
    • Arlt S, Beisiegel U, Kontush A. Lipid peroxidation in neurodegeneration: new insights into Alzheimer's disease. Curr Opin Lipidol 2002; 13:289-294 (Pubitemid 34592286)
    • (2002) Current Opinion in Lipidology , vol.13 , Issue.3 , pp. 289-294
    • Arlt, S.1    Beisiegel, U.2    Kontush, A.3
  • 46
    • 0036224435 scopus 로고    scopus 로고
    • The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease
    • DOI 10.1016/S0197-4580(01)00327-X, PII S019745800100327X
    • Selley ML, Close DR, Stern SE. The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease. Neurobiol Aging 2002; 23:383-388 (Pubitemid 34312021)
    • (2002) Neurobiology of Aging , vol.23 , Issue.3 , pp. 383-388
    • Selley, M.L.1    Close, D.R.2    Stern, S.E.3
  • 47
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta- Peptide: Role of the lipid peroxidation product 4-hydroxynonenal
    • Keller JN, Pang Z, Geddes JW, Begley JG, Germeyer A, Waeg G, et al. Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide-role of the lipid peroxidation product 4-hydroxynonenal. J Neurochem 1997; 69:273-284 (Pubitemid 27274182)
    • (1997) Journal of Neurochemistry , vol.69 , Issue.1 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, A.5    Waeg, G.6    Mattson, M.P.7
  • 48
    • 0042536471 scopus 로고    scopus 로고
    • Neuronal and glial calcium signaling in Alzheimer's disease
    • DOI 10.1016/S0143-4160(03)00128-3
    • Mattson MP, Chan SL. Neuronal and glial calcium signaling in Alzheimer's disease. Cell Calcium 2003; 34:385-397 (Pubitemid 37021231)
    • (2003) Cell Calcium , vol.34 , Issue.4-5 , pp. 385-397
    • Mattson, M.P.1    Chan, S.L.2
  • 49
    • 0037382957 scopus 로고    scopus 로고
    • H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating Jnos and p38MAPK
    • Tamagno E, Robino G, Obbili A, Bardini P, Aragno M, Parola M, et al. H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating Jnos and p38MAPK. Exp Neurol 2003; 180:144-155
    • (2003) Exp Neurol , vol.180 , pp. 144-155
    • Tamagno, E.1    Robino, G.2    Obbili, A.3    Bardini, P.4    Aragno, M.5    Parola, M.6
  • 51
    • 0031754202 scopus 로고    scopus 로고
    • Increased nuclear DNA oxidation in the brain in Alzheimer' s disease
    • Gabbita SP, Lovell MA, Markesbery WR. Increased nuclear DNA oxidation in the brain in Alzheimer's disease. J Neurochem 1998; 71:2034-2040 (Pubitemid 28491559)
    • (1998) Journal of Neurochemistry , vol.71 , Issue.5 , pp. 2034-2040
    • Gabbita, S.P.1    Lovell, M.A.2    Markesbery, W.R.3
  • 56
    • 0032933750 scopus 로고    scopus 로고
    • Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF
    • DOI 10.1046/j.1471-4159.1999.0720771.x
    • Lovell MA, Gabbita SP, Markesbery WR. Increased DNA oxidation and decreassed levels of repair products in Alzheimer's disease ventricular CSF. J Neurochem 1999; 72:771-776 (Pubitemid 29055242)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.2 , pp. 771-776
    • Lovell, M.A.1    Gabbita, S.P.2    Markesbery, W.R.3
  • 57
    • 0028152717 scopus 로고
    • Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
    • DOI 10.1002/ana.410360510
    • Mecocci P, MacGarvey U, Beal MF. Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann Neurol 1994; 36:747-751 (Pubitemid 24337634)
    • (1994) Annals of Neurology , vol.36 , Issue.5 , pp. 747-751
    • Mecocci, P.1    MacGarvey, U.2    Beal, M.F.3
  • 60
    • 0028329916 scopus 로고
    • 14C]lysine into protein
    • DOI 10.1006/abio.1994.1046
    • Prabhakaram M, Ortwerth BJ. Determination of glycation crosslinking by the sugardependent incorporation of [14C]lysine into protein. Anal Biochem 1994; 216:305-312 (Pubitemid 24076012)
    • (1994) Analytical Biochemistry , vol.216 , Issue.2 , pp. 305-312
    • Prabhakaram, M.1    Ortwerth, B.J.2
  • 61
    • 0030908734 scopus 로고    scopus 로고
    • Enhanced binding of advanced glycation endproducts (AGE) by the ApoE4 isoform links the mechanism of plaque deposition in Alzheimer's disease
    • DOI 10.1016/S0304-3940(97)00266-8, PII S0304394097002668
    • Li YM, Dickson DW. Enhanced binding of advanced glycation endproducts (age) by the apoe4 isoform links the mechanism of plaque deposition in Alzheimer's disease. Neurosci Lett 1997; 226:155-158 (Pubitemid 27201967)
    • (1997) Neuroscience Letters , vol.226 , Issue.3 , pp. 155-158
    • Li, Y.M.1    Dickson, D.W.2
  • 62
    • 0032527056 scopus 로고    scopus 로고
    • Advanced glycation endproducts are associated with Hirano bodies in Alzheimer's disease
    • DOI 10.1016/S0006-8993(98)00328-X, PII S000689939800328X
    • Munch G, Cunningham AM, Riederer P, Braak E. Advanced glycation endproducts are associated with Hirano bodies in Alzheimer's disease. Brain Res 1998; 796:307-310 (Pubitemid 28343263)
    • (1998) Brain Research , vol.796 , Issue.1-2 , pp. 307-310
    • Munch, G.1    Cunningham, A.M.2    Riederer, P.3    Braak, E.4
  • 64
    • 0032196604 scopus 로고    scopus 로고
    • Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules
    • González C, Farías G, Maccioni RB. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules. Cell Mol Biol 1998; 44:1117-1127
    • (1998) Cell Mol Biol , vol.44 , pp. 1117-1127
    • González, C.1    Farías, G.2    Maccioni, R.B.3
  • 65
    • 0032197142 scopus 로고    scopus 로고
    • Tau glycation is involved in aggregation of the protein but not in the formation of filaments
    • Ledesma MD, Pérez M, Colaco C, Avila J. Tau glycation is involved in aggregation of the protein but not in the formation of filaments. Cell Mol Biol 1998; 44:1111-1116
    • (1998) Cell Mol Biol , vol.44 , pp. 1111-1116
    • Ledesma, M.D.1    Pérez, M.2    Colaco, C.3    Avila, J.4
  • 68
    • 0028230473 scopus 로고
    • Glycation: A pathological modification in neuropathies?: a hypothesis
    • Colaco CA, Harrington CR. Glycation: a pathological modification in neuropathies?: a hypothesis. Neuroreport 1994; 5:859-861
    • (1994) Neuroreport , vol.5 , pp. 859-861
    • Colaco, C.A.1    Harrington, C.R.2
  • 71
    • 0029414741 scopus 로고
    • Altered regulation of brain glucose metabolism as a cause of neurodegenerative disorders?
    • Blum-Degen D, Frölich L, Hoyer S, Riederer P. Altered regulation of brain glucose metabolism as a cause of neurodegenerative disorders? J Neural Transm 1995; 46:139-147
    • (1995) J Neural Transm , vol.46 , pp. 139-147
    • Blum-Degen, D.1    Frölich, L.2    Hoyer, S.3    Riederer, P.4
  • 72
    • 0031928535 scopus 로고    scopus 로고
    • Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? a challenging hypothesis
    • DOI 10.1007/s007020050067
    • Hoyer S. Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J Neural Transm 1998; 105:415-422 (Pubitemid 28365026)
    • (1998) Journal of Neural Transmission , vol.105 , Issue.4-5 , pp. 415-422
    • Hoyer, S.1
  • 73
    • 0032468013 scopus 로고    scopus 로고
    • Risk factors for vascular disease and dementia
    • Breteler MM, Bots ML, Ott A, Hofman A. Risk factors for vascular disease and dementia. Haemostasis 1998; 28:167-173 (Pubitemid 29309598)
    • (1998) Haemostasis , vol.28 , Issue.3-4 , pp. 167-173
    • Breteler, M.M.B.1    Bots, M.L.2    Ott, A.3    Hofman, A.4
  • 77
    • 0032707190 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, cognitive impairment and dementia
    • Stewart R, Liolitsa D. Type 2 diabetes mellitus, cognitive impairment and dementia. Diabet Med 1999; 16:93-112.
    • (1999) Diabet Med , vol.16 , pp. 93-112
    • Stewart, R.1    Liolitsa, D.2
  • 78
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta- Peptide: Role of the lipid peroxidation product 4-hydroxynonenal
    • Keller JN, Pang Z, Geddes JW, Begley JG, Germeyer A, Waeg G, et al. Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal. J Neurochem 1997; 69:273-284 (Pubitemid 27274182)
    • (1997) Journal of Neurochemistry , vol.69 , Issue.1 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, A.5    Waeg, G.6    Mattson, M.P.7
  • 80
    • 0029058571 scopus 로고
    • Alzheimer neurofibrillary lesions: Molecular nature and potential roles of different components
    • Yen SH, Liu WK, Hall FL, Yan SD, Stern D, Dickson DW. Alzheimer neurofibrillary lesions: molecular nature and potential roles of different components. Neurobiol Aging 1995; 16:381-387
    • (1995) Neurobiol Aging , vol.16 , pp. 381-387
    • Yen, S.H.1    Liu, W.K.2    Hall, F.L.3    Yan, S.D.4    Stern, D.5    Dickson, D.W.6
  • 81
    • 0028237566 scopus 로고
    • In vivo phosphorylation in the rat basal nucleus induces PHF-like and APP immunoreactivity
    • Arendt T, Hanisch F, Holzer M, Brückner MK. In vivo phosphorylation in the rat basal nucleus induces PHF-like and APP immunoreactivity. Neuroreport 1994; 5:1397-1400
    • (1994) Neuroreport , vol.5 , pp. 1397-1400
    • Arendt, T.1    Hanisch, F.2    Holzer, M.3    Brückner, M.K.4
  • 82
    • 0028786849 scopus 로고
    • Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A
    • Arendt T, Holzer M, Fruth R, Brückner MK, Gärtner U. Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A. Neuroscience 1995; 69:691-698
    • (1995) Neuroscience , vol.69 , pp. 691-698
    • Arendt, T.1    Holzer, M.2    Fruth, R.3    Brückner, M.K.4    Gärtner, U.5
  • 83
    • 23744449436 scopus 로고    scopus 로고
    • Reversible in vivo phosphorylation of tau induced by okadaic acid and by unspecific brain lesion in rat
    • Janke C, Gartner U, Holzer M, Arendt T. Reversible in vivo phosphorylation of tau induced by okadaic acid and by unspecific brain lesion in rat. J Hirnforsch 1998; 39:143-153 (Pubitemid 128682841)
    • (1998) Journal of Brain Research , vol.39 , Issue.2 , pp. 143-153
    • Janke, G.1    Gartner, U.2    Holzer, M.3    Arendt, T.4
  • 84
    • 0031719122 scopus 로고    scopus 로고
    • Advanced glycation end products in neurodegeneration: More than early markers of oxidative stress?
    • Münch G, Gerlach M, Sian J, Wong A, Riederer P. Advanced glycation end products in neurodegeneration: more than early markers of oxidative stress? Ann Neurol 1998; 44:85-88
    • (1998) Ann Neurol , vol.44 , pp. 85-88
    • Münch, G.1    Gerlach, M.2    Sian, J.3    Wong, A.4    Riederer, P.5
  • 85
    • 0029833134 scopus 로고    scopus 로고
    • New hypothesis on etiopathogenesis of Alzheimer syndrome. Advanced glycation end products (AGEs)
    • Thome J, Kornhuber J, Münch G, Schinzel R, Taneli Y, Zielke B, et al. New hypothesis on etiopathogenesis of Alzheimer syndrome. Advanced glycation end products (AGEs) Nervenarzt 1996; 67:924-929
    • (1996) Nervenarzt , vol.67 , pp. 924-929
    • Thome, J.1    Kornhuber, J.2    Münch, G.3    Schinzel, R.4    Taneli, Y.5    Zielke, B.6
  • 87
    • 0034795140 scopus 로고    scopus 로고
    • The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
    • DOI 10.1172/JCI200114002
    • Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 2001; 108:949-955 (Pubitemid 32946067)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.7 , pp. 949-955
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 90
    • 28244474852 scopus 로고    scopus 로고
    • Micronutrients and Alzheimer's disease
    • Staehelin HB. Micronutrients and Alzheimer's disease. Proc Nutr Soc 2005; 64:565-570
    • (2005) Proc Nutr Soc , vol.64 , pp. 565-570
    • Staehelin, H.B.1
  • 91
    • 0032576959 scopus 로고    scopus 로고
    • Implication of altered redox regulation by antioxidant enzymes in the increased plasma pentosidine, an advanced glycation end product, in uremia
    • DOI 10.1006/bbrc.1998.8523
    • Ueda Y, Miyata T, Hashimoto T, Yamada H, Izuhara Y, Sakai H, et al. Implication of altered redox regulation by antioxidant enzymes in the increased plasma pentosidine, an advanced glycation end product, in uremia. Biochem Biophys Res Commun 1998; 245:785-790 (Pubitemid 28413995)
    • (1998) Biochemical and Biophysical Research Communications , vol.245 , Issue.3 , pp. 785-790
    • Ueda, Y.1    Miyata, T.2    Hashimoto, T.3    Yamada, H.4    Izuhara, Y.5    Sakai, H.6    Kurokawa, K.7
  • 92
    • 0028951461 scopus 로고
    • Mechanism of autoxidative glycosylation: Identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose
    • Wells-Knecht KJ, Zyzak DV, Litchfield JE, Thorpe SR, Baynes JW. Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose. Biochemistry 1995; 34:3702-3709
    • (1995) Biochemistry , vol.34 , pp. 3702-3709
    • Wells-Knecht, K.J.1    Zyzak, D.V.2    Litchfield, J.E.3    Thorpe, S.R.4    Baynes, J.W.5
  • 94
    • 0033958696 scopus 로고    scopus 로고
    • Vitamin E and Alzheimer's disease: The basis for additional clinical trials
    • Grundman M. Vitamin E and Alzheimer's disease: the basis for additional clinical trials. Am J Clin Nutr 2000; 71:630-636
    • (2000) Am J Clin Nutr , vol.71 , pp. 630-636
    • Grundman, M.1
  • 96
    • 0029160270 scopus 로고
    • Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs
    • Breitner JC, Welsh KA, Helms MJ, Gaskell PC, Gau BA, Roses AD, et al. Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs. Neurobiol Aging 1995; 16:523-530
    • (1995) Neurobiol Aging , vol.16 , pp. 523-530
    • Breitner, J.C.1    Welsh, K.A.2    Helms, M.J.3    Gaskell, P.C.4    Gau, B.A.5    Roses, A.D.6
  • 97
    • 0037971180 scopus 로고    scopus 로고
    • 2 release in primary rat microglia
    • DOI 10.1046/j.1471-4159.2003.01822.x
    • Fiebich BL, Lieb K, Kammerer N, Hull M. Synergistic inhibitory effect of ascorbic acid and acetylsalicylic acid on prostaglandin E2 release in primary rat microglia. J Neurochem 2003; 86:173-178 (Pubitemid 36753858)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.1 , pp. 173-178
    • Fiebich, B.L.1    Lieb, K.2    Kammerer, N.3    Hull, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.