Depletion of CXCR2 inhibits γ-secretase activity and amyloid-β production in a murine model of Alzheimer's disease

Cytokine

Volumn 53, Issue 2, 2011, Pages 163-169

  Bakshi, Pancham ^a   Margenthaler, Elaina ^a   Reed, Jon ^a   Crawford, Fiona ^a   Mullan, Michael ^a  

^a ROSKAMP INSTITUTE   (United States)

Author keywords

secretase; Alzheimer's disease; Amyloid ; CXCR2; Inflammation

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CHEMOKINE RECEPTOR CXCR2; GAMMA SECRETASE; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME INHIBITION; ENZYME SUBSTRATE; FEMALE; HUMAN; HUMAN CELL; MALE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; ENDOCYTOSIS; HUMANS; MICE; MICE, KNOCKOUT; MUTATION; PRESENILINS; RECEPTORS, INTERLEUKIN-8B; SOLUBILITY;

MURINAE; MUS;

EID: 78651074925     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.10.008     Document Type: Article

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