-
1
-
-
84960466895
-
A global view of pulmonary hypertension
-
[CrossRef]
-
Hoeper, M.M., Humbert, M., Souza, R., Idrees, M., Kawut, S.M., Sliwa-Hahnle, K., Jing, Z.-C., Gibbs, J.S.R. A global view of pulmonary hypertension. Lancet Respir. Med. 2016. [CrossRef]
-
(2016)
Lancet Respir. Med
-
-
Hoeper, M.M.1
Humbert, M.2
Souza, R.3
Idrees, M.4
Kawut, S.M.5
Sliwa-Hahnle, K.6
Jing, Z.-C.7
Gibbs, J.S.R.8
-
2
-
-
84960362801
-
Treatment of pulmonary hypertension
-
[CrossRef]
-
Hoeper, M.M., McLaughlin, V.V., Dalaan, A.M.A., Satoh, T., Galiè, N. Treatment of pulmonary hypertension. Lancet Respir. Med. 2016. [CrossRef]
-
(2016)
Lancet Respir. Med
-
-
Hoeper, M.M.1
McLaughlin, V.V.2
Dalaan, A.M.A.3
Satoh, T.4
Galiè, N.5
-
3
-
-
84890753066
-
Relevant issues in the pathology and pathobiology of pulmonary hypertension
-
[CrossRef] [PubMed]
-
Tuder, R.M., Archer, S.L., Dorfmüller, P., Erzurum, S.C., Guignabert, C., Michelakis, E., Rabinovitch, M., Schermuly, R., Stenmark, K.R., Morrell, N.W. Relevant issues in the pathology and pathobiology of pulmonary hypertension. J. Am. Coll. Cardiol. 2013, 62, D4–D12. [CrossRef] [PubMed]
-
(2013)
J. Am. Coll. Cardiol
, vol.62
, pp. DD4-D12
-
-
Tuder, R.M.1
Archer, S.L.2
Dorfmüller, P.3
Erzurum, S.C.4
Guignabert, C.5
Michelakis, E.6
Rabinovitch, M.7
Schermuly, R.8
Stenmark, K.R.9
Morrell, N.W.10
-
4
-
-
55249093143
-
Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Humbert, M., Montani, D., Perros, F., Dorfmüller, P., Adnot, S., Eddahibi, S. Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension. Vascul. Pharmacol. 2008, 49, 113–118. [CrossRef] [PubMed]
-
(2008)
Vascul. Pharmacol
, vol.49
, pp. 113-118
-
-
Humbert, M.1
Montani, D.2
Perros, F.3
Dorfmüller, P.4
Adnot, S.5
Eddahibi, S.6
-
5
-
-
84870523226
-
Molecular pathogenesis of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Rabinovitch, M. Molecular pathogenesis of pulmonary arterial hypertension. J. Clin. Investig. 2012, 122, 4306–4313. [CrossRef] [PubMed]
-
(2012)
J. Clin. Investig
, vol.122
, pp. 4306-4313
-
-
Rabinovitch, M.1
-
6
-
-
84906316920
-
Inflammation in pulmonary hypertension: What we know and what we could logically and safely target first
-
[CrossRef] [PubMed]
-
Cohen-Kaminsky, S., Hautefort, A., Price, L., Humbert, M., Perros, F. Inflammation in pulmonary hypertension: What we know and what we could logically and safely target first. Drug Discov. Today 2014, 19, 1251–1256. [CrossRef] [PubMed]
-
(2014)
Drug Discov. Today
, vol.19
, pp. 1251-1256
-
-
Cohen-Kaminsky, S.1
Hautefort, A.2
Price, L.3
Humbert, M.4
Perros, F.5
-
7
-
-
84925511350
-
Mitochondrial dynamics in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Ryan, J., Dasgupta, A., Huston, J., Chen, K.-H., Archer, S.L. Mitochondrial dynamics in pulmonary arterial hypertension. J. Mol. Med. 2015, 93, 229–242. [CrossRef] [PubMed]
-
(2015)
J. Mol. Med
, vol.93
, pp. 229-242
-
-
Ryan, J.1
Dasgupta, A.2
Huston, J.3
Chen, K.-H.4
Archer, S.L.5
-
8
-
-
84941360761
-
Downregulation of MicroRNA-126 Contributes to the Failing Right Ventricle in Pulmonary Arterial Hypertension
-
[CrossRef] [PubMed]
-
Potus, F., Ruffenach, G., Dahou, A., Thebault, C., Breuils-Bonnet, S., Tremblay, È., Nadeau, V., Paradis, R., Graydon, C., Wong, R., et al. Downregulation of MicroRNA-126 Contributes to the Failing Right Ventricle in Pulmonary Arterial Hypertension. Circulation 2015, 132, 932–943. [CrossRef] [PubMed]
-
(2015)
Circulation
, vol.132
, pp. 932-943
-
-
Potus, F.1
Ruffenach, G.2
Dahou, A.3
Thebault, C.4
Breuils-Bonnet, S.5
Tremblay, È.6
Nadeau, V.7
Paradis, R.8
Graydon, C.9
Wong, R.10
-
9
-
-
84905831453
-
Impaired angiogenesis and peripheral muscle microcirculation loss contribute to exercise intolerance in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Potus, F., Malenfant, S., Graydon, C., Mainguy, V., Tremblay, È., Breuils-Bonnet, S., Ribeiro, F., Porlier, A., Maltais, F., Bonnet, S., et al. Impaired angiogenesis and peripheral muscle microcirculation loss contribute to exercise intolerance in pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2014, 190, 318–328. [CrossRef] [PubMed]
-
(2014)
Am. J. Respir. Crit. Care Med
, vol.190
, pp. 318-328
-
-
Potus, F.1
Malenfant, S.2
Graydon, C.3
Mainguy, V.4
Tremblay, È.5
Breuils-Bonnet, S.6
Ribeiro, F.7
Porlier, A.8
Maltais, F.9
Bonnet, S.10
-
10
-
-
84929513782
-
Endothelial-to-mesenchymal transition in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Ranchoux, B., Antigny, F., Rucker-Martin, C., Hautefort, A., Péchoux, C., Bogaard, H.J., Dorfmüller, P., Remy, S., Lecerf, F., Planté, S., et al. Endothelial-to-mesenchymal transition in pulmonary hypertension. Circulation 2015, 131, 1006–1018. [CrossRef] [PubMed]
-
(2015)
Circulation
, vol.131
, pp. 1006-1018
-
-
Ranchoux, B.1
Antigny, F.2
Rucker-Martin, C.3
Hautefort, A.4
Péchoux, C.5
Bogaard, H.J.6
Dorfmüller, P.7
Remy, S.8
Lecerf, F.9
Planté, S.10
-
11
-
-
84872674552
-
The role of inflammation and autoimmunity in the pathophysiology of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Kherbeck, N., Tamby, M.C., Bussone, G., Dib, H., Perros, F., Humbert, M., Mouthon, L. The role of inflammation and autoimmunity in the pathophysiology of pulmonary arterial hypertension. Clin. Rev. Allergy Immunol. 2013, 44, 31–38. [CrossRef] [PubMed]
-
(2013)
Clin. Rev. Allergy Immunol
, vol.44
, pp. 31-38
-
-
Kherbeck, N.1
Tamby, M.C.2
Bussone, G.3
Dib, H.4
Perros, F.5
Humbert, M.6
Mouthon, L.7
-
12
-
-
84894362215
-
Signal transduction in the development of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Malenfant, S., Neyron, A.-S., Paulin, R., Potus, F., Meloche, J., Provencher, S., Bonnet, S. Signal transduction in the development of pulmonary arterial hypertension. Pulm. Circ. 2013, 3, 278–293. [CrossRef] [PubMed]
-
(2013)
Pulm. Circ
, vol.3
, pp. 278-293
-
-
Malenfant, S.1
Neyron, A.-S.2
Paulin, R.3
Potus, F.4
Meloche, J.5
Provencher, S.6
Bonnet, S.7
-
13
-
-
84880849903
-
Pulmonary arterial hypertension: A flavor of autoimmunity
-
Perros, F., Humbert, M., Cohen-Kaminsky, S. Pulmonary arterial hypertension: A flavor of autoimmunity. Méd. Sci. 2013, 29, 607–616.
-
(2013)
Méd. Sci
, vol.29
, pp. 607-616
-
-
Perros, F.1
Humbert, M.2
Cohen-Kaminsky, S.3
-
14
-
-
84879816142
-
Pulmonary arterial hypertension. Orphanet
-
[CrossRef] [PubMed]
-
Montani, D., Günther, S., Dorfmüller, P., Perros, F., Girerd, B., Garcia, G., Jaïs, X., Savale, L., Artaud-Macari, E., Price, L.C., et al. Pulmonary arterial hypertension. Orphanet J. Rare Dis. 2013, 8, 97. [CrossRef] [PubMed]
-
(2013)
J. Rare Dis
, vol.8
, pp. 97
-
-
Montani, D.1
Günther, S.2
Dorfmüller, P.3
Perros, F.4
Girerd, B.5
Garcia, G.6
Jaïs, X.7
Savale, L.8
Artaud-Macari, E.9
Price, L.C.10
-
15
-
-
84891863007
-
Targeted therapies in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Montani, D., Chaumais, M.-C., Guignabert, C., Günther, S., Girerd, B., Jaïs, X., Algalarrondo, V., Price, L.C., Savale, L., Sitbon, O., et al. Targeted therapies in pulmonary arterial hypertension. Pharmacol. Ther. 2014, 141, 172–191. [CrossRef] [PubMed]
-
(2014)
Pharmacol. Ther
, vol.141
, pp. 172-191
-
-
Montani, D.1
Chaumais, M.-C.2
Guignabert, C.3
Günther, S.4
Girerd, B.5
Jaïs, X.6
Algalarrondo, V.7
Price, L.C.8
Savale, L.9
Sitbon, O.10
-
16
-
-
77954758530
-
Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
-
[CrossRef] [PubMed]
-
Humbert, M., Sitbon, O., Chaouat, A., Bertocchi, M., Habib, G., Gressin, V., Yaïci, A., Weitzenblum, E., Cordier, J.-F., Chabot, F., et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 2010, 122, 156–163. [CrossRef] [PubMed]
-
(2010)
Circulation
, vol.122
, pp. 156-163
-
-
Humbert, M.1
Sitbon, O.2
Chaouat, A.3
Bertocchi, M.4
Habib, G.5
Gressin, V.6
Yaïci, A.7
Weitzenblum, E.8
Cordier, J.-F.9
Chabot, F.10
-
17
-
-
84902950876
-
Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Rabinovitch, M., Guignabert, C., Humbert, M., Nicolls, M.R. Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circ. Res. 2014, 115, 165–175. [CrossRef] [PubMed]
-
(2014)
Circ. Res
, vol.115
, pp. 165-175
-
-
Rabinovitch, M.1
Guignabert, C.2
Humbert, M.3
Nicolls, M.R.4
-
18
-
-
0035463112
-
Vascular remodeling in hypertension: Roles of apoptosis, inflammation, and fibrosis
-
[CrossRef] [PubMed]
-
Intengan, H.D., Schiffrin, E.L. Vascular remodeling in hypertension: Roles of apoptosis, inflammation, and fibrosis. Hypertension 2001, 38, 581–587. [CrossRef] [PubMed]
-
(2001)
Hypertension
, vol.38
, pp. 581-587
-
-
Intengan, H.D.1
Schiffrin, E.L.2
-
19
-
-
0003422388
-
DNA Damage and Repair and Their Role in Carcinogenesis
-
W.H. Freeman: New York, NY, USA
-
Lodish, H., Berk, A., Zipursky, S.L., Matsudaira, P., Baltimore, D., Darnell, J. DNA Damage and Repair and Their Role in Carcinogenesis. In Molecular Cell Biology, W.H. Freeman: New York, NY, USA, 2000.
-
(2000)
Molecular Cell Biology
-
-
Lodish, H.1
Berk, A.2
Zipursky, S.L.3
Matsudaira, P.4
Baltimore, D.5
Darnell, J.6
-
20
-
-
84964285738
-
Adaptation and remodelling of the pulmonary circulation in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Vaillancourt, M., Ruffenach, G., Meloche, J., Bonnet, S.: Adaptation and remodelling of the pulmonary circulation in pulmonary hypertension. Can. J. Cardiol. 2015, 31, 407–415. [CrossRef] [PubMed]
-
(2015)
Can. J. Cardiol
, vol.31
, pp. 407-415
-
-
Vaillancourt, M.1
Ruffenach, G.2
Meloche, J.3
Bonnet, S.4
-
21
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
[CrossRef] [PubMed]
-
Lindahl, T. Instability and decay of the primary structure of DNA. Nature 1993, 362, 709–715. [CrossRef] [PubMed]
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
22
-
-
0025305055
-
Possible mutagens derived from lipids and lipid precursors
-
[CrossRef]
-
Esterbauer, H., Eckl, P., Ortner, A. Possible mutagens derived from lipids and lipid precursors. Mutat. Res. 1990, 238, 223–233. [CrossRef]
-
(1990)
Mutat. Res
, vol.238
, pp. 223-233
-
-
Esterbauer, H.1
Eckl, P.2
Ortner, A.3
-
23
-
-
0032565572
-
Gene silencing and endogenous DNA methylation in mammalian cells
-
[CrossRef]
-
Holliday, R., Ho, T.: Gene silencing and endogenous DNA methylation in mammalian cells. Mutat. Res. 1998, 400, 361–368. [CrossRef]
-
(1998)
Mutat. Res
, vol.400
, pp. 361-368
-
-
Holliday, R.1
Ho, T.2
-
24
-
-
2942523593
-
Endogenous DNA damage in humans: A review of quantitative data
-
[CrossRef] [PubMed]
-
De Bont, R., van Larebeke, N.: Endogenous DNA damage in humans: A review of quantitative data. Mutagenesis 2004, 19, 169–185. [CrossRef] [PubMed]
-
(2004)
Mutagenesis
, vol.19
, pp. 169-185
-
-
De Bont, R.1
Van Larebeke, N.2
-
25
-
-
70349859881
-
DNA damage, aging, and cancer
-
[CrossRef] [PubMed]
-
Hoeijmakers, J.H.J.: DNA damage, aging, and cancer. N. Engl. J. Med. 2009, 361, 1475–1485. [CrossRef] [PubMed]
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 1475-1485
-
-
Hoeijmakers, J.H.J.1
-
26
-
-
84969218969
-
Systemic DNA damage responses in aging and diseases
-
[CrossRef] [PubMed]
-
Ribezzo, F., Shiloh, Y., Schumacher, B. Systemic DNA damage responses in aging and diseases. Semin. Cancer Biol. 2016. [CrossRef] [PubMed]
-
(2016)
Semin. Cancer Biol
-
-
Ribezzo, F.1
Shiloh, Y.2
Schumacher, B.3
-
27
-
-
84906303775
-
Mechanisms underlying mutational signatures in human cancers
-
[CrossRef] [PubMed]
-
Helleday, T., Eshtad, S., Nik-Zainal, S. Mechanisms underlying mutational signatures in human cancers. Nat. Rev. Genet. 2014, 15, 585–598. [CrossRef] [PubMed]
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 585-598
-
-
Helleday, T.1
Eshtad, S.2
Nik-Zainal, S.3
-
28
-
-
0015504248
-
Rate of depurination of native deoxyribonucleic acid
-
[CrossRef] [PubMed]
-
Lindahl, T., Nyberg, B. Rate of depurination of native deoxyribonucleic acid. Biochemistry 1972, 11, 3610–3618. [CrossRef] [PubMed]
-
(1972)
Biochemistry
, vol.11
, pp. 3610-3618
-
-
Lindahl, T.1
Nyberg, B.2
-
29
-
-
0348140585
-
Abasic sites in DNA: Repair and biological consequences in Saccharomyces cerevisiae
-
[CrossRef] [PubMed]
-
Boiteux, S., Guillet, M. Abasic sites in DNA: Repair and biological consequences in Saccharomyces cerevisiae. DNA Repair 2004, 3, 1–12. [CrossRef] [PubMed]
-
(2004)
DNA Repair
, vol.3
, pp. 1-12
-
-
Boiteux, S.1
Guillet, M.2
-
30
-
-
48249095920
-
Single-strand break repair and genetic disease
-
[PubMed]
-
Caldecott, K.W.: Single-strand break repair and genetic disease. Nat. Rev. Genet. 2008, 9, 619–631.[PubMed]
-
(2008)
Nat. Rev. Genet
, vol.9
, pp. 619-631
-
-
Caldecott, K.W.1
-
31
-
-
84975886810
-
Double-Strand Breaks in DNA Can Be Lethal to a Cell
-
accessed on 23 March 2016
-
Negritto, C. Double-Strand Breaks in DNA Can Be Lethal to a Cell. How Do Cells Fix Them? Available online: http://www.nature.com/scitable/topicpage/repairing-double-strand-dna-breaks-14432332 (accessed on 23 March 2016).
-
How Do Cells Fix Them?
-
-
Negritto, C.1
-
32
-
-
84938204945
-
DNA-protein crosslink repair
-
[CrossRef]
-
Stingele, J., Jentsch, S. DNA-protein crosslink repair. Nat. Rev. Mol. Cell Biol. 2015, 16, 455–460. [CrossRef]
-
(2015)
Nat. Rev. Mol. Cell Biol
, vol.16
, pp. 455-460
-
-
Stingele, J.1
Jentsch, S.2
-
33
-
-
33644623520
-
Formation and repair of interstrand cross-links in DNA
-
[CrossRef] [PubMed]
-
Noll, D.M., Mason, T.M., Miller, P.S.: Formation and repair of interstrand cross-links in DNA. Chem. Rev. 2006, 106, 277–301. [CrossRef] [PubMed]
-
(2006)
Chem. Rev
, vol.106
, pp. 277-301
-
-
Noll, D.M.1
Mason, T.M.2
Miller, P.S.3
-
34
-
-
84957106626
-
DNA, the central molecule of aging
-
[CrossRef] [PubMed]
-
Lenart, P., Krejci, L. DNA, the central molecule of aging. Mutat. Res. 2016, 786, 1–7. [CrossRef] [PubMed]
-
(2016)
Mutat. Res
, vol.786
, pp. 1-7
-
-
Lenart, P.1
Krejci, L.2
-
35
-
-
0037178748
-
Interfaces between the detection, signaling, and repair of DNA damage
-
[CrossRef] [PubMed]
-
Rouse, J., Jackson, S.P. Interfaces between the detection, signaling, and repair of DNA damage. Science 2002, 297, 547–551. [CrossRef] [PubMed]
-
(2002)
Science
, vol.297
, pp. 547-551
-
-
Rouse, J.1
Jackson, S.P.2
-
36
-
-
33751419716
-
Surviving the breakup: The DNA damage checkpoint
-
[CrossRef] [PubMed]
-
Harrison, J.C., Haber, J.E. Surviving the breakup: The DNA damage checkpoint. Annu. Rev. Genet. 2006, 40, 209–235. [CrossRef] [PubMed]
-
(2006)
Annu. Rev. Genet
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
37
-
-
36749022214
-
The DNA damage response: Ten years after
-
[CrossRef] [PubMed]
-
Harper, J.W., Elledge, S.J. The DNA damage response: Ten years after. Mol. Cell 2007, 28, 739–745. [CrossRef] [PubMed]
-
(2007)
Mol. Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
38
-
-
36949000941
-
DNA strand break repair and human genetic disease
-
[CrossRef] [PubMed]
-
McKinnon, P.J., Caldecott, K.W.: DNA strand break repair and human genetic disease. Annu. Rev. Genom. Hum. Genet. 2007, 8, 37–55. [CrossRef] [PubMed]
-
(2007)
Annu. Rev. Genom. Hum. Genet
, vol.8
, pp. 37-55
-
-
McKinnon, P.J.1
Caldecott, K.W.2
-
39
-
-
0035837587
-
The major human abasic endonuclease: Formation, consequences and repair of abasic lesions in DNA
-
[CrossRef]
-
Wilson, D.M., Barsky, D. The major human abasic endonuclease: Formation, consequences and repair of abasic lesions in DNA. Mutat. Res. 2001, 485, 283–307. [CrossRef]
-
(2001)
Mutat. Res
, vol.485
, pp. 283-307
-
-
Wilson, D.M.1
Barsky, D.2
-
40
-
-
27844501168
-
Molecular and biological roles of Ape1 protein in mammalian base excision repair
-
[CrossRef] [PubMed]
-
Demple, B., Sung, J.-S. Molecular and biological roles of Ape1 protein in mammalian base excision repair. DNA Repair 2005, 4, 1442–1449. [CrossRef] [PubMed]
-
(2005)
DNA Repair
, vol.4
, pp. 1442-1449
-
-
Demple, B.1
Sung, J.-S.2
-
41
-
-
0242268065
-
Mammalian DNA base excision repair proteins: Their interactions and role in repair of oxidative DNA damage
-
[CrossRef]
-
Izumi, T., Wiederhold, L.R., Roy, G., Roy, R., Jaiswal, A., Bhakat, K.K., Mitra, S., Hazra, T.K. Mammalian DNA base excision repair proteins: Their interactions and role in repair of oxidative DNA damage. Toxicology 2003, 193, 43–65. [CrossRef]
-
(2003)
Toxicology
, vol.193
, pp. 43-65
-
-
Izumi, T.1
Wiederhold, L.R.2
Roy, G.3
Roy, R.4
Jaiswal, A.5
Bhakat, K.K.6
Mitra, S.7
Hazra, T.K.8
-
42
-
-
0345448125
-
Repair of abasic sites in DNA
-
[CrossRef] [PubMed]
-
Dianov, G.L., Sleeth, K.M., Dianova, I.I., Allinson, S.L. Repair of abasic sites in DNA. Mutat. Res. 2003, 531, 157–163. [CrossRef] [PubMed]
-
(2003)
Mutat. Res
, vol.531
, pp. 157-163
-
-
Dianov, G.L.1
Sleeth, K.M.2
Dianova, I.I.3
Allinson, S.L.4
-
43
-
-
84862970400
-
Overview of base excision repair biochemistry
-
[CrossRef] [PubMed]
-
Kim, Y.-J., Wilson, D.M. Overview of base excision repair biochemistry. Curr. Mol. Pharmacol. 2012, 5, 3–13. [CrossRef] [PubMed]
-
(2012)
Curr. Mol. Pharmacol
, vol.5
, pp. 3-13
-
-
Kim, Y.-J.1
Wilson, D.M.2
-
44
-
-
0024456894
-
Zinc-binding domain of poly(ADP-ribose)polymerase participates in the recognition of single strand breaks on DNA
-
[CrossRef]
-
Ménissier-de Murcia, J., Molinete, M., Gradwohl, G., Simonin, F., de Murcia, G. Zinc-binding domain of poly(ADP-ribose)polymerase participates in the recognition of single strand breaks on DNA. J. Mol. Biol. 1989, 210, 229–233. [CrossRef]
-
(1989)
J. Mol. Biol
, vol.210
, pp. 229-233
-
-
Ménissier-De Murcia, J.1
Molinete, M.2
Gradwohl, G.3
Simonin, F.4
de Murcia, G.5
-
45
-
-
78650670562
-
Apurinic/apyrimidinic (AP) site recognition by the 51-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)
-
[CrossRef] [PubMed]
-
Khodyreva, S.N., Prasad, R., Ilina, E.S., Sukhanova, M.V., Kutuzov, M.M., Liu, Y., Hou, E.W., Wilson, S.H., Lavrik, O.I. Apurinic/apyrimidinic (AP) site recognition by the 51-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1). Proc. Natl. Acad. Sci. USA 2010, 107, 22090–22095. [CrossRef] [PubMed]
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 22090-22095
-
-
Khodyreva, S.N.1
Prasad, R.2
Ilina, E.S.3
Sukhanova, M.V.4
Kutuzov, M.M.5
Liu, Y.6
Hou, E.W.7
Wilson, S.H.8
Lavrik, O.I.9
-
46
-
-
34547225606
-
Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase
-
[CrossRef] [PubMed]
-
Fisher, A.E.O., Hochegger, H., Takeda, S., Caldecott, K.W. Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase. Mol. Cell. Biol. 2007, 27, 5597–5605. [CrossRef] [PubMed]
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 5597-5605
-
-
Fisher, A.E.O.1
Hochegger, H.2
Takeda, S.3
Caldecott, K.W.4
-
47
-
-
3042627356
-
XRCC1-DNA polymerase beta interaction is required for efficient base excision repair
-
[CrossRef] [PubMed]
-
Dianova, I.I., Sleeth, K.M., Allinson, S.L., Parsons, J.L., Breslin, C., Caldecott, K.W., Dianov, G.L. XRCC1-DNA polymerase beta interaction is required for efficient base excision repair. Nucleic Acids Res. 2004, 32, 2550–2555. [CrossRef] [PubMed]
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 2550-2555
-
-
Dianova, I.I.1
Sleeth, K.M.2
Allinson, S.L.3
Parsons, J.L.4
Breslin, C.5
Caldecott, K.W.6
Dianov, G.L.7
-
48
-
-
0029957245
-
XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular “nick-sensor” in vitro
-
[CrossRef] [PubMed]
-
Caldecott, K.W., Aoufouchi, S., Johnson, P., Shall, S. XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular “nick-sensor” in vitro. Nucleic Acids Res. 1996, 24, 4387–4394. [CrossRef] [PubMed]
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 4387-4394
-
-
Caldecott, K.W.1
Aoufouchi, S.2
Johnson, P.3
Shall, S.4
-
49
-
-
0031844311
-
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage
-
[CrossRef] [PubMed]
-
Masson, M., Niedergang, C., Schreiber, V., Muller, S., Menissier-de Murcia, J., de Murcia, G. XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell. Biol. 1998, 18, 3563–3571. [CrossRef] [PubMed]
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 3563-3571
-
-
Masson, M.1
Niedergang, C.2
Schreiber, V.3
Muller, S.4
Menissier-De Murcia, J.5
de Murcia, G.6
-
50
-
-
84871538934
-
Regulation of chromatin structure by poly(ADP-ribosyl)ation
-
[CrossRef] [PubMed]
-
Beneke, S. Regulation of chromatin structure by poly(ADP-ribosyl)ation. Front. Genet. 2012, 3, 169. [CrossRef] [PubMed]
-
(2012)
Front. Genet
, vol.3
, pp. 169
-
-
Beneke, S.1
-
51
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
[CrossRef] [PubMed]
-
Rouleau, M., Patel, A., Hendzel, M.J., Kaufmann, S.H., Poirier, G.G. PARP inhibition: PARP1 and beyond. Nat. Rev. Cancer 2010, 10, 293–301. [CrossRef] [PubMed]
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 293-301
-
-
Rouleau, M.1
Patel, A.2
Hendzel, M.J.3
Kaufmann, S.H.4
Poirier, G.G.5
-
52
-
-
33745867638
-
Poly(ADP-ribose): Novel functions for an old molecule
-
[CrossRef] [PubMed]
-
Schreiber, V., Dantzer, F., Ame, J.-C., de Murcia, G. Poly(ADP-ribose): Novel functions for an old molecule. Nat. Rev. Mol. Cell Biol. 2006, 7, 517–528. [CrossRef] [PubMed]
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 517-528
-
-
Schreiber, V.1
Dantzer, F.2
Ame, J.-C.3
de Murcia, G.4
-
53
-
-
84904642416
-
Understanding nucleotide excision repair and its roles in cancer and ageing
-
[CrossRef] [PubMed]
-
Marteijn, J.A., Lans, H., Vermeulen, W., Hoeijmakers, J.H.J. Understanding nucleotide excision repair and its roles in cancer and ageing. Nat. Rev. Mol. Cell Biol. 2014, 15, 465–481. [CrossRef] [PubMed]
-
(2014)
Nat. Rev. Mol. Cell Biol
, vol.15
, pp. 465-481
-
-
Marteijn, J.A.1
Lans, H.2
Vermeulen, W.3
Hoeijmakers, J.H.J.4
-
54
-
-
84940047092
-
Schumacher, B. DNA repair mechanisms in cancer development and therapy
-
[CrossRef] [PubMed]
-
Torgovnick, A., Schumacher, B. DNA repair mechanisms in cancer development and therapy. Front. Genet. 2015, 6, 157. [CrossRef] [PubMed]
-
(2015)
Front. Genet
, vol.6
, pp. 157
-
-
Torgovnick, A.1
-
55
-
-
56749157389
-
Transcription-coupled DNA repair: Two decades of progress and surprises
-
[CrossRef] [PubMed]
-
Hanawalt, P.C., Spivak, G. Transcription-coupled DNA repair: Two decades of progress and surprises. Nat. Rev. Mol. Cell Biol. 2008, 9, 958–970. [CrossRef] [PubMed]
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 958-970
-
-
Hanawalt, P.C.1
Spivak, G.2
-
56
-
-
84865387901
-
Rare hereditary diseases with defects in DNA-repair
-
[PubMed]
-
Knoch, J., Kamenisch, Y., Kubisch, C., Berneburg, M. Rare hereditary diseases with defects in DNA-repair. Eur. J. Dermatol. 2012, 22, 443–455.[PubMed]
-
(2012)
Eur. J. Dermatol
, vol.22
, pp. 443-455
-
-
Knoch, J.1
Kamenisch, Y.2
Kubisch, C.3
Berneburg, M.4
-
57
-
-
84919423844
-
Mismatch repair deficiency as a therapeutic strategy
-
[CrossRef] [PubMed]
-
Guillotin, D., Martin, S.A. Exploiting DNA mismatch repair deficiency as a therapeutic strategy. Exp. Cell Res. 2014, 329, 110–115. [CrossRef] [PubMed]
-
(2014)
Exp. Cell Res
, vol.329
, pp. 110-115
-
-
Guillotin, D.1
Martin, S.A.2
Exploiting, D.3
-
58
-
-
38049125557
-
Mechanisms and functions of DNA mismatch repair
-
[CrossRef] [PubMed]
-
Li, G.-M. Mechanisms and functions of DNA mismatch repair. Cell Res. 2008, 18, 85–98. [CrossRef] [PubMed]
-
(2008)
Cell Res
, vol.18
, pp. 85-98
-
-
Li, G.-M.1
-
59
-
-
0029943449
-
Mismatch repair in replication fidelity, genetic recombination, and cancer biology
-
[CrossRef] [PubMed]
-
Modrich, P., Lahue, R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 1996, 65, 101–133. [CrossRef] [PubMed]
-
(1996)
Annu. Rev. Biochem
, vol.65
, pp. 101-133
-
-
Modrich, P.1
Lahue, R.2
-
60
-
-
22244492665
-
DNA mismatch repair
-
[CrossRef] [PubMed]
-
Kunkel, T.A., Erie, D.A.: DNA mismatch repair. Annu. Rev. Biochem. 2005, 74, 681–710. [CrossRef] [PubMed]
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 681-710
-
-
Kunkel, T.A.1
Erie, D.A.2
-
61
-
-
33646187811
-
The multifaceted mismatch-repair system
-
[CrossRef] [PubMed]
-
Jiricny, J. The multifaceted mismatch-repair system. Nat. Rev. Mol. Cell Biol. 2006, 7, 335–346. [CrossRef] [PubMed]
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 335-346
-
-
Jiricny, J.1
-
62
-
-
84880586724
-
DNA repair mechanisms in dividing and non-dividing cells
-
[CrossRef] [PubMed]
-
Iyama, T., Wilson, D.M. DNA repair mechanisms in dividing and non-dividing cells. DNA Repair 2013, 12, 620–636. [CrossRef] [PubMed]
-
(2013)
DNA Repair
, vol.12
, pp. 620-636
-
-
Iyama, T.1
Wilson, D.M.2
-
63
-
-
0030860574
-
DNA mismatch repair in mammals: Role in disease and meiosis
-
[CrossRef]
-
Arnheim, N., Shibata, D. DNA mismatch repair in mammals: Role in disease and meiosis. Curr. Opin. Genet. Dev. 1997, 7, 364–370. [CrossRef]
-
(1997)
Curr. Opin. Genet. Dev
, vol.7
, pp. 364-370
-
-
Arnheim, N.1
Shibata, D.2
-
64
-
-
0035101436
-
DNA mismatch repair and cancer
-
[CrossRef]
-
Peltomäki, P. DNA mismatch repair and cancer. Mutat. Res. 2001, 488, 77–85. [CrossRef]
-
(2001)
Mutat. Res
, vol.488
, pp. 77-85
-
-
Peltomäki, P.1
-
65
-
-
0043133778
-
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
-
[CrossRef] [PubMed]
-
Ding, Q., Reddy, Y.V.R., Wang, W., Woods, T., Douglas, P., Ramsden, D.A., Lees-Miller, S.P., Meek, K. Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol. Cell. Biol. 2003, 23, 5836–5848. [CrossRef] [PubMed]
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5836-5848
-
-
Ding, Q.1
Reddy, Y.V.R.2
Wang, W.3
Woods, T.4
Douglas, P.5
Ramsden, D.A.6
Lees-Miller, S.P.7
Meek, K.8
-
66
-
-
34249945536
-
DNA double-strand break repair: From mechanistic understanding to cancer treatment
-
[CrossRef] [PubMed]
-
Helleday, T., Lo, J., van Gent, D.C., Engelward, B.P. DNA double-strand break repair: From mechanistic understanding to cancer treatment. DNA Repair 2007, 6, 923–935. [CrossRef] [PubMed]
-
(2007)
DNA Repair
, vol.6
, pp. 923-935
-
-
Helleday, T.1
Lo, J.2
van Gent, D.C.3
Engelward, B.P.4
-
67
-
-
84888626405
-
Modernizing the nonhomologous end-joining repertoire: Alternative and classical NHEJ share the stage
-
[CrossRef] [PubMed]
-
Deriano, L., Roth, D.B. Modernizing the nonhomologous end-joining repertoire: Alternative and classical NHEJ share the stage. Annu. Rev. Genet. 2013, 47, 433–455. [CrossRef] [PubMed]
-
(2013)
Annu. Rev. Genet
, vol.47
, pp. 433-455
-
-
Deriano, L.1
Roth, D.B.2
-
68
-
-
84958177765
-
DNA repair and aging: The impact of the p53 family
-
[CrossRef] [PubMed]
-
Nicolai, S., Rossi, A., di Daniele, N., Melino, G., Annicchiarico-Petruzzelli, M., Raschellà, G. DNA repair and aging: The impact of the p53 family. Aging 2015, 7, 1050–1065. [CrossRef] [PubMed]
-
(2015)
Aging
, vol.7
, pp. 1050-1065
-
-
Nicolai, S.1
Rossi, A.2
di Daniele, N.3
Melino, G.4
Annicchiarico-Petruzzelli, M.5
Raschellà, G.6
-
69
-
-
31044432090
-
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
-
[CrossRef] [PubMed]
-
Ahnesorg, P., Smith, P., Jackson, S.P. XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell 2006, 124, 301–313. [CrossRef] [PubMed]
-
(2006)
Cell
, vol.124
, pp. 301-313
-
-
Ahnesorg, P.1
Smith, P.2
Jackson, S.P.3
-
70
-
-
84938882573
-
XRCC4/XLF Interaction is variably required for DNA repair and is not required for ligase IV stimulation
-
[CrossRef] [PubMed]
-
Roy, S., de Melo, A.J., Xu, Y., Tadi, S.K., Négrel, A., Hendrickson, E., Modesti, M., Meek, K. XRCC4/XLF Interaction is variably required for DNA repair and is not required for ligase IV stimulation. Mol. Cell. Biol. 2015, 35, 3017–3028. [CrossRef] [PubMed]
-
(2015)
Mol. Cell. Biol
, vol.35
, pp. 3017-3028
-
-
Roy, S.1
de Melo, A.J.2
Xu, Y.3
Tadi, S.K.4
Négrel, A.5
Hendrickson, E.6
Modesti, M.7
Meek, K.8
-
71
-
-
80053212145
-
Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway
-
[CrossRef] [PubMed]
-
Della-Maria, J., Zhou, Y., Tsai, M.-S., Kuhnlein, J., Carney, J.P., Paull, T.T., Tomkinson, A.E. Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. J. Biol. Chem. 2011, 286, 33845–33853. [CrossRef] [PubMed]
-
(2011)
J. Biol. Chem
, vol.286
, pp. 33845-33853
-
-
Della-Maria, J.1
Zhou, Y.2
Tsai, M.-S.3
Kuhnlein, J.4
Carney, J.P.5
Paull, T.T.6
Tomkinson, A.E.7
-
72
-
-
84867386682
-
Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks
-
[PubMed]
-
Boboila, C., Alt, F.W., Schwer, B. Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks. Adv. Immunol. 2012, 116, 1–49.[PubMed]
-
(2012)
Adv. Immunol
, vol.116
, pp. 1-49
-
-
Boboila, C.1
Alt, F.W.2
Schwer, B.3
-
73
-
-
84878627489
-
PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks
-
[CrossRef] [PubMed]
-
Metzger, M.J., Stoddard, B.L., Monnat, R.J. PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks. DNA Repair 2013, 12, 529–534. [CrossRef] [PubMed]
-
(2013)
DNA Repair
, vol.12
, pp. 529-534
-
-
Metzger, M.J.1
Stoddard, B.L.2
Monnat, R.J.3
-
74
-
-
84881101184
-
End-joining, translocations and cancer
-
[CrossRef] [PubMed]
-
Bunting, S.F., Nussenzweig, A. End-joining, translocations and cancer. Nat. Rev. Cancer 2013, 13, 443–454. [CrossRef] [PubMed]
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 443-454
-
-
Bunting, S.F.1
Nussenzweig, A.2
-
75
-
-
11244280890
-
Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
-
[CrossRef] [PubMed]
-
Audebert, M., Salles, B., Calsou, P.: Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. J. Biol. Chem. 2004, 279, 55117–55126. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55117-55126
-
-
Audebert, M.1
Salles, B.2
Calsou, P.3
-
76
-
-
80053204232
-
The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes
-
[CrossRef] [PubMed]
-
Cuneo, M.J., Gabel, S.A., Krahn, J.M., Ricker, M.A., London, R.E. The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes. Nucleic Acids Res. 2011, 39, 7816–7827. [CrossRef] [PubMed]
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 7816-7827
-
-
Cuneo, M.J.1
Gabel, S.A.2
Krahn, J.M.3
Ricker, M.A.4
London, R.E.5
-
77
-
-
84945916597
-
Microhomology-mediated end joining: A back-up survival mechanismor dedicated pathway?
-
[CrossRef] [PubMed]
-
Sfeir, A., Symington, L.S. Microhomology-mediated end joining: A back-up survival mechanismor dedicated pathway? Trends Biochem. Sci. 2015, 40, 701–714. [CrossRef] [PubMed]
-
(2015)
Trends Biochem. Sci
, vol.40
, pp. 701-714
-
-
Sfeir, A.1
Symington, L.S.2
-
78
-
-
56649088073
-
Mystery of DNA repair: The role of the MRN complex and ATM kinase in DNA damage repair
-
[CrossRef] [PubMed]
-
Czornak, K., Chughtai, S., Chrzanowska, K.H. Mystery of DNA repair: The role of the MRN complex and ATM kinase in DNA damage repair. J. Appl. Genet. 2008, 49, 383–396. [CrossRef] [PubMed]
-
(2008)
J. Appl. Genet
, vol.49
, pp. 383-396
-
-
Czornak, K.1
Chughtai, S.2
Chrzanowska, K.H.3
-
79
-
-
77955841725
-
The MRN complex in double-strand break repair and telomere maintenance
-
[CrossRef] [PubMed]
-
Lamarche, B.J., Orazio, N.I., Weitzman, M.D. The MRN complex in double-strand break repair and telomere maintenance. FEBS Lett. 2010, 584, 3682–3695. [CrossRef] [PubMed]
-
(2010)
FEBS Lett
, vol.584
, pp. 3682-3695
-
-
Lamarche, B.J.1
Orazio, N.I.2
Weitzman, M.D.3
-
80
-
-
0034664813
-
SURVEY AND SUMMARY: Holliday junction resolvases and related nucleases: Identification of new families, phyletic distribution and evolutionary trajectories
-
[CrossRef] [PubMed]
-
Aravind, L., Makarova, K.S., Koonin, E.V. SURVEY AND SUMMARY: Holliday junction resolvases and related nucleases: Identification of new families, phyletic distribution and evolutionary trajectories. Nucleic Acids Res. 2000, 28, 3417–3432. [CrossRef] [PubMed]
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 3417-3432
-
-
Aravind, L.1
Makarova, K.S.2
Koonin, E.V.3
-
82
-
-
56749119855
-
Identification of Holliday junction resolvases from humans and yeast
-
[CrossRef] [PubMed]
-
Ip, S.C.Y., Rass, U., Blanco, M.G., Flynn, H.R., Skehel, J.M., West, S.C. Identification of Holliday junction resolvases from humans and yeast. Nature 2008, 456, 357–361. [CrossRef] [PubMed]
-
(2008)
Nature
, vol.456
, pp. 357-361
-
-
Ip, S.C.Y.1
Rass, U.2
Blanco, M.G.3
Flynn, H.R.4
Skehel, J.M.5
West, S.C.6
-
83
-
-
84903783162
-
The dissolution of double Holliday junctions
-
[CrossRef] [PubMed]
-
Bizard, A.H., Hickson, I.D. The dissolution of double Holliday junctions. Cold Spring Harb. Perspect. Biol. 2014, 6, a016477. [CrossRef] [PubMed]
-
(2014)
Cold Spring Harb. Perspect. Biol
, vol.6
-
-
Bizard, A.H.1
Hickson, I.D.2
-
84
-
-
84903877237
-
Molecular mechanism of double Holliday junction dissolution
-
[CrossRef] [PubMed]
-
Swuec, P., Costa, A. Molecular mechanism of double Holliday junction dissolution. Cell Biosci. 2014, 4, 36. [CrossRef] [PubMed]
-
(2014)
Cell Biosci
, vol.4
, pp. 36
-
-
Swuec, P.1
Costa, A.2
-
85
-
-
84895898969
-
Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1
-
[CrossRef] [PubMed]
-
Bocquet, N., Bizard, A.H., Abdulrahman, W., Larsen, N.B., Faty, M., Cavadini, S., Bunker, R.D., Kowalczykowski, S.C., Cejka, P., Hickson, I.D., et al. Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1. Nat. Struct. Mol. Biol. 2014, 21, 261–268. [CrossRef] [PubMed]
-
(2014)
Nat. Struct. Mol. Biol
, vol.21
, pp. 261-268
-
-
Bocquet, N.1
Bizard, A.H.2
Abdulrahman, W.3
Larsen, N.B.4
Faty, M.5
Cavadini, S.6
Bunker, R.D.7
Kowalczykowski, S.C.8
Cejka, P.9
Hickson, I.D.10
-
86
-
-
50649100744
-
Mechanism of eukaryotic homologous recombination
-
[CrossRef] [PubMed]
-
San Filippo, J., Sung, P., Klein, H. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 2008, 77, 229–257. [CrossRef] [PubMed]
-
(2008)
Annu. Rev. Biochem
, vol.77
, pp. 229-257
-
-
San Filippo, J.1
Sung, P.2
Klein, H.3
-
87
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
[CrossRef] [PubMed]
-
Moynahan, M.E., Jasin, M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 2010, 11, 196–207. [CrossRef] [PubMed]
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
88
-
-
80755187806
-
Double-strand break end resection and repair pathway choice
-
[CrossRef] [PubMed]
-
Symington, L.S., Gautier, J.: Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 2011, 45, 247–271. [CrossRef] [PubMed]
-
(2011)
Annu. Rev. Genet
, vol.45
, pp. 247-271
-
-
Symington, L.S.1
Gautier, J.2
-
89
-
-
84942234504
-
Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
-
[CrossRef] [PubMed]
-
Bakr, A., Oing, C., Köcher, S., Borgmann, K., Dornreiter, I., Petersen, C., Dikomey, E., Mansour, W.Y. Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation. Nucleic Acids Res. 2015, 43, 3154–3166. [CrossRef] [PubMed]
-
(2015)
Nucleic Acids Res
, vol.43
, pp. 3154-3166
-
-
Bakr, A.1
Oing, C.2
Köcher, S.3
Borgmann, K.4
Dornreiter, I.5
Petersen, C.6
Dikomey, E.7
Mansour, W.Y.8
-
90
-
-
14944342130
-
Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wild-type p53
-
[CrossRef] [PubMed]
-
Dahm-Daphi, J., Hubbe, P., Horvath, F., El-Awady, R.A., Bouffard, K.E., Powell, S.N., Willers, H. Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wild-type p53. Oncogene 2005, 24, 1663–1672. [CrossRef] [PubMed]
-
(2005)
Oncogene
, vol.24
, pp. 1663-1672
-
-
Dahm-Daphi, J.1
Hubbe, P.2
Horvath, F.3
El-Awady, R.A.4
Bouffard, K.E.5
Powell, S.N.6
Willers, H.7
-
91
-
-
84922394643
-
Involvement of p53 in the repair of DNA double strand breaks: Multifaceted roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)
-
[PubMed]
-
Menon, V., Povirk, L. Involvement of p53 in the repair of DNA double strand breaks: Multifaceted roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). Subcell. Biochem. 2014, 85, 321–336.[PubMed]
-
(2014)
Subcell. Biochem
, vol.85
, pp. 321-336
-
-
Menon, V.1
Povirk, L.2
-
92
-
-
84891014338
-
Double-strand break repair: 53BP1 comes into focus
-
[CrossRef] [PubMed]
-
Panier, S., Boulton, S.J. Double-strand break repair: 53BP1 comes into focus. Nat. Rev. Mol. Cell Biol. 2014, 15, 7–18. [CrossRef] [PubMed]
-
(2014)
Nat. Rev. Mol. Cell Biol
, vol.15
, pp. 7-18
-
-
Panier, S.1
Boulton, S.J.2
-
93
-
-
33745833032
-
The role of BRCA1 in non-homologous end-joining
-
[CrossRef] [PubMed]
-
Bau, D.-T., Mau, Y.-C., Shen, C.-Y. The role of BRCA1 in non-homologous end-joining. Cancer Lett. 2006, 240, 1–8. [CrossRef] [PubMed]
-
(2006)
Cancer Lett
, vol.240
, pp. 1-8
-
-
Bau, D.-T.1
Mau, Y.-C.2
Shen, C.-Y.3
-
94
-
-
0035057806
-
BRCA1 and BRCA2 and the genetics of breast and ovarian cancer
-
[CrossRef] [PubMed]
-
Welcsh, P.L., King, M.C. BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum. Mol. Genet. 2001, 10, 705–713. [CrossRef] [PubMed]
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 705-713
-
-
Welcsh, P.L.1
King, M.C.2
-
95
-
-
84958165181
-
Mutant p53 drives cancer by subverting multiple tumor suppression pathways
-
[CrossRef] [PubMed]
-
Haupt, S., Raghu, D., Haupt, Y. Mutant p53 drives cancer by subverting multiple tumor suppression pathways. Front. Oncol. 2016, 6, 12. [CrossRef] [PubMed]
-
(2016)
Front. Oncol
, vol.6
, pp. 12
-
-
Haupt, S.1
Raghu, D.2
Haupt, Y.3
-
96
-
-
84906245025
-
Is homologous recombination really an error-free process?
-
[CrossRef] [PubMed]
-
Guirouilh-Barbat, J., Lambert, S., Bertrand, P., Lopez, B.S. Is homologous recombination really an error-free process? Front. Genet. 2014, 5. [CrossRef] [PubMed]
-
(2014)
Front. Genet
, pp. 5
-
-
Guirouilh-Barbat, J.1
Lambert, S.2
Bertrand, P.3
Lopez, B.S.4
-
97
-
-
84965087141
-
Homology and enzymatic requirements of microhomology-dependent alternative end joining
-
[CrossRef] [PubMed]
-
Sharma, S., Javadekar, S.M., Pandey, M., Srivastava, M., Kumari, R., Raghavan, S.C. Homology and enzymatic requirements of microhomology-dependent alternative end joining. Cell Death Dis. 2015, 6, e1697. [CrossRef] [PubMed]
-
(2015)
Cell Death Dis
, vol.6
-
-
Sharma, S.1
Javadekar, S.M.2
Pandey, M.3
Srivastava, M.4
Kumari, R.5
Raghavan, S.C.6
-
98
-
-
84902116617
-
DNA double-strand break repair pathway choice and cancer
-
[CrossRef] [PubMed]
-
Aparicio, T., Baer, R., Gautier, J. DNA double-strand break repair pathway choice and cancer. DNA Repair 2014, 19, 169–175. [CrossRef] [PubMed]
-
(2014)
DNA Repair
, vol.19
, pp. 169-175
-
-
Aparicio, T.1
Baer, R.2
Gautier, J.3
-
99
-
-
84953790832
-
Risky business: Microhomology-mediated end joining
-
[CrossRef] [PubMed]
-
Sinha, S., Villarreal, D., Shim, E.Y., Lee, S.E. Risky business: Microhomology-mediated end joining. Mutat. Res. 2016. [CrossRef] [PubMed]
-
(2016)
Mutat. Res
-
-
Sinha, S.1
Villarreal, D.2
Shim, E.Y.3
Lee, S.E.4
-
100
-
-
84924232532
-
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
-
[CrossRef] [PubMed]
-
Kent, T., Chandramouly, G., McDevitt, S.M., Ozdemir, A.Y., Pomerantz, R.T. Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ. Nat. Struct. Mol. Biol. 2015, 22, 230–237. [CrossRef] [PubMed]
-
(2015)
Nat. Struct. Mol. Biol
, vol.22
, pp. 230-237
-
-
Kent, T.1
Chandramouly, G.2
McDevitt, S.M.3
Ozdemir, A.Y.4
Pomerantz, R.T.5
-
101
-
-
77955820979
-
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability
-
[CrossRef] [PubMed]
-
Lemée, F., Bergoglio, V., Fernandez-Vidal, A., Machado-Silva, A., Pillaire, M.-J., Bieth, A., Gentil, C., Baker, L., Martin, A.-L., Leduc, C., et al. DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Proc. Natl. Acad. Sci. USA 2010, 107, 13390–13395. [CrossRef] [PubMed]
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 13390-13395
-
-
Lemée, F.1
Bergoglio, V.2
Fernandez-Vidal, A.3
Machado-Silva, A.4
Pillaire, M.-J.5
Bieth, A.6
Gentil, C.7
Baker, L.8
Martin, A.-L.9
Leduc, C.10
-
102
-
-
79251525596
-
Overexpression of POLQ confers a poor prognosis in early breast cancer patients
-
[CrossRef] [PubMed]
-
Higgins, G.S., Harris, A.L., Prevo, R., Helleday, T., McKenna, W.G., Buffa, F.M. Overexpression of POLQ confers a poor prognosis in early breast cancer patients. Oncotarget 2010, 1, 175–184. [CrossRef] [PubMed]
-
(2010)
Oncotarget
, vol.1
, pp. 175-184
-
-
Higgins, G.S.1
Harris, A.L.2
Prevo, R.3
Helleday, T.4
McKenna, W.G.5
Buffa, F.M.6
-
103
-
-
0032031727
-
Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension
-
[CrossRef] [PubMed]
-
Lee, S.D., Shroyer, K.R., Markham, N.E., Cool, C.D., Voelkel, N.F., Tuder, R.M. Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. J. Clin. Investig. 1998, 101, 927–934. [CrossRef] [PubMed]
-
(1998)
J. Clin. Investig
, vol.101
, pp. 927-934
-
-
Lee, S.D.1
Shroyer, K.R.2
Markham, N.E.3
Cool, C.D.4
Voelkel, N.F.5
Tuder, R.M.6
-
104
-
-
0032433228
-
Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension
-
[CrossRef] [PubMed]
-
Tuder, R.M., Radisavljevic, Z., Shroyer, K.R., Polak, J.M., Voelkel, N.F. Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension. Am. J. Respir. Crit. Care Med. 1998, 158, 1999–2001. [CrossRef] [PubMed]
-
(1998)
Am. J. Respir. Crit. Care Med
, vol.158
, pp. 1999-2001
-
-
Tuder, R.M.1
Radisavljevic, Z.2
Shroyer, K.R.3
Polak, J.M.4
Voelkel, N.F.5
-
105
-
-
0035910729
-
Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension
-
[CrossRef] [PubMed]
-
Yeager, M.E., Halley, G.R., Golpon, H.A., Voelkel, N.F., Tuder, R.M.: Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension. Circ. Res. 2001, 88, E2–E11. [CrossRef] [PubMed]
-
(2001)
Circ. Res
, vol.88
, pp. EE2-E11
-
-
Yeager, M.E.1
Halley, G.R.2
Golpon, H.A.3
Voelkel, N.F.4
Tuder, R.M.5
-
106
-
-
78349266115
-
Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Aldred, M.A., Comhair, S.A., Varella-Garcia, M., Asosingh, K., Xu, W., Noon, G.P., Thistlethwaite, P.A., Tuder, R.M., Erzurum, S.C., Geraci, M.W., et al. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2010, 182, 1153–1160. [CrossRef] [PubMed]
-
(2010)
Am. J. Respir. Crit. Care Med
, vol.182
, pp. 1153-1160
-
-
Aldred, M.A.1
Comhair, S.A.2
Varella-Garcia, M.3
Asosingh, K.4
Xu, W.5
Noon, G.P.6
Thistlethwaite, P.A.7
Tuder, R.M.8
Erzurum, S.C.9
Geraci, M.W.10
-
107
-
-
84938075246
-
Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension
-
[CrossRef] [PubMed]
-
Federici, C., Drake, K.M., Rigelsky, C.M., McNelly, L.N., Meade, S.L., Comhair, S.A.A., Erzurum, S.C., Aldred, M.A. Increased Mutagen Sensitivity and DNA Damage in Pulmonary Arterial Hypertension. Am. J. Respir. Crit. Care Med. 2015, 192, 219–228. [CrossRef] [PubMed]
-
(2015)
Am. J. Respir. Crit. Care Med
, vol.192
, pp. 219-228
-
-
Federici, C.1
Drake, K.M.2
Rigelsky, C.M.3
McNelly, L.N.4
Meade, S.L.5
Comhair, S.A.A.6
Erzurum, S.C.7
Aldred, M.A.8
-
108
-
-
84890738424
-
Updated clinical classification of pulmonary hypertension
-
[CrossRef] [PubMed]
-
Simonneau, G., Gatzoulis, M.A., Adatia, I., Celermajer, D., Denton, C., Ghofrani, A., Gomez Sanchez, M.A., Krishna Kumar, R., Landzberg, M., Machado, R.F., et al. Updated clinical classification of pulmonary hypertension. J. Am. Coll. Cardiol. 2013, 62, D34–D41. [CrossRef] [PubMed]
-
(2013)
J. Am. Coll. Cardiol
, vol.62
, pp. D34-D41
-
-
Simonneau, G.1
Gatzoulis, M.A.2
Adatia, I.3
Celermajer, D.4
Denton, C.5
Ghofrani, A.6
Gomez Sanchez, M.A.7
Krishna Kumar, R.8
Landzberg, M.9
Machado, R.F.10
-
109
-
-
33746379082
-
Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Sanchez, O., Sitbon, O., Jaïs, X., Simonneau, G., Humbert, M. Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension. Chest 2006, 130, 182–189. [CrossRef] [PubMed]
-
(2006)
Chest
, vol.130
, pp. 182-189
-
-
Sanchez, O.1
Sitbon, O.2
Jaïs, X.3
Simonneau, G.4
Humbert, M.5
-
110
-
-
0029938442
-
Improvement of severe pulmonary hypertension in a patient with SLE
-
[CrossRef] [PubMed]
-
Karmochkine, M., Wechsler, B., Godeau, P., Brenot, F., Jagot, J.L., Simonneau, G. Improvement of severe pulmonary hypertension in a patient with SLE. Ann. Rheum. Dis. 1996, 55, 561–562. [CrossRef] [PubMed]
-
(1996)
Ann. Rheum. Dis
, vol.55
, pp. 561-562
-
-
Karmochkine, M.1
Wechsler, B.2
Godeau, P.3
Brenot, F.4
Jagot, J.L.5
Simonneau, G.6
-
111
-
-
84893129805
-
Anti-inflammatory and immunosuppressive agents in PAH. Handb
-
[PubMed]
-
Meloche, J., Renard, S., Provencher, S., Bonnet, S.: Anti-inflammatory and immunosuppressive agents in PAH. Handb. Exp. Pharmacol. 2013, 218, 437–476.[PubMed]
-
(2013)
Exp. Pharmacol
, vol.218
, pp. 437-476
-
-
Meloche, J.1
Renard, S.2
Provencher, S.3
Bonnet, S.4
-
112
-
-
33846125922
-
POEMS syndrome-related pulmonary hypertension is steroid-responsive
-
[CrossRef] [PubMed]
-
Jouve, P., Humbert, M., Chauveheid, M.-P., Jaïs, X., Papo, T. POEMS syndrome-related pulmonary hypertension is steroid-responsive. Respir. Med. 2007, 101, 353–355. [CrossRef] [PubMed]
-
(2007)
Respir. Med
, vol.101
, pp. 353-355
-
-
Jouve, P.1
Humbert, M.2
Chauveheid, M.-P.3
Jaïs, X.4
Papo, T.5
-
113
-
-
0043028479
-
Inflammation in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Dorfmüller, P., Perros, F., Balabanian, K., Humbert, M. Inflammation in pulmonary arterial hypertension. Eur. Respir. J. 2003, 22, 358–363. [CrossRef] [PubMed]
-
(2003)
Eur. Respir. J
, vol.22
, pp. 358-363
-
-
Dorfmüller, P.1
Perros, F.2
Balabanian, K.3
Humbert, M.4
-
114
-
-
84856802817
-
Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Perros, F., Dorfmüller, P., Montani, D., Hammad, H., Waelput, W., Girerd, B., Raymond, N., Mercier, O., Mussot, S., Cohen-Kaminsky, S., et al. Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2012, 185, 311–321. [CrossRef] [PubMed]
-
(2012)
Am. J. Respir. Crit. Care Med
, vol.185
, pp. 311-321
-
-
Perros, F.1
Dorfmüller, P.2
Montani, D.3
Hammad, H.4
Waelput, W.5
Girerd, B.6
Raymond, N.7
Mercier, O.8
Mussot, S.9
Cohen-Kaminsky, S.10
-
115
-
-
84893630181
-
CXCL13 in tertiary lymphoid tissues: Sites of production are different from sites of functional localization
-
[CrossRef] [PubMed]
-
Cohen-Kaminsky, S., Ranchoux, B., Perros, F. CXCL13 in tertiary lymphoid tissues: Sites of production are different from sites of functional localization. Am. J. Respir. Crit. Care Med. 2014, 189, 369–370. [CrossRef] [PubMed]
-
(2014)
Am. J. Respir. Crit. Care Med
, vol.189
, pp. 369-370
-
-
Cohen-Kaminsky, S.1
Ranchoux, B.2
Perros, F.3
-
116
-
-
84855467311
-
Inflammation in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Price, L.C., Wort, S.J., Perros, F., Dorfmüller, P., Huertas, A., Montani, D., Cohen-Kaminsky, S., Humbert, M. Inflammation in pulmonary arterial hypertension. Chest 2012, 141, 210–221. [CrossRef] [PubMed]
-
(2012)
Chest
, vol.141
, pp. 210-221
-
-
Price, L.C.1
Wort, S.J.2
Perros, F.3
Dorfmüller, P.4
Huertas, A.5
Montani, D.6
Cohen-Kaminsky, S.7
Humbert, M.8
-
117
-
-
84872578985
-
Cytotoxic cells and granulysin in pulmonary arterial hypertension and pulmonary veno-occlusive disease
-
[CrossRef] [PubMed]
-
Perros, F., Cohen-Kaminsky, S., Gambaryan, N., Girerd, B., Raymond, N., Klingelschmitt, I., Huertas, A., Mercier, O., Fadel, E., Simonneau, G., et al. Cytotoxic cells and granulysin in pulmonary arterial hypertension and pulmonary veno-occlusive disease. Am. J. Respir. Crit. Care Med. 2013, 187, 189–196. [CrossRef] [PubMed]
-
(2013)
Am. J. Respir. Crit. Care Med
, vol.187
, pp. 189-196
-
-
Perros, F.1
Cohen-Kaminsky, S.2
Gambaryan, N.3
Girerd, B.4
Raymond, N.5
Klingelschmitt, I.6
Huertas, A.7
Mercier, O.8
Fadel, E.9
Simonneau, G.10
-
118
-
-
79957982619
-
C-Kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Montani, D., Perros, F., Gambaryan, N., Girerd, B., Dorfmuller, P., Price, L.C., Huertas, A., Hammad, H., Lambrecht, B., Simonneau, G., et al. C-Kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2011, 184, 116–123. [CrossRef] [PubMed]
-
(2011)
Am. J. Respir. Crit. Care Med
, vol.184
, pp. 116-123
-
-
Montani, D.1
Perros, F.2
Gambaryan, N.3
Girerd, B.4
Dorfmuller, P.5
Price, L.C.6
Huertas, A.7
Hammad, H.8
Lambrecht, B.9
Simonneau, G.10
-
119
-
-
33847696236
-
Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension
-
[CrossRef] [PubMed]
-
Perros, F., Dorfmüller, P., Souza, R., Durand-Gasselin, I., Mussot, S., Mazmanian, M., Hervé, P., Emilie, D., Simonneau, G., Humbert, M. Dendritic cell recruitment in lesions of human and experimental pulmonary hypertension. Eur. Respir. J. 2007, 29, 462–468. [CrossRef] [PubMed]
-
(2007)
Eur. Respir. J
, vol.29
, pp. 462-468
-
-
Perros, F.1
Dorfmüller, P.2
Souza, R.3
Durand-Gasselin, I.4
Mussot, S.5
Mazmanian, M.6
Hervé, P.7
Emilie, D.8
Simonneau, G.9
Humbert, M.10
-
120
-
-
0029062419
-
Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension
-
[CrossRef] [PubMed]
-
Humbert, M., Monti, G., Brenot, F., Sitbon, O., Portier, A., Grangeot-Keros, L., Duroux, P., Galanaud, P., Simonneau, G., Emilie, D. Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension. Am. J. Respir. Crit. Care Med. 1995, 151, 1628–1631. [CrossRef] [PubMed]
-
(1995)
Am. J. Respir. Crit. Care Med
, vol.151
, pp. 1628-1631
-
-
Humbert, M.1
Monti, G.2
Brenot, F.3
Sitbon, O.4
Portier, A.5
Grangeot-Keros, L.6
Duroux, P.7
Galanaud, P.8
Simonneau, G.9
Emilie, D.10
-
121
-
-
77956390581
-
Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Soon, E., Holmes, A.M., Treacy, C.M., Doughty, N.J., Southgate, L., Machado, R.D., Trembath, R.C., Jennings, S., Barker, L., Nicklin, P., et al. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension. Circulation 2010, 122, 920–927. [CrossRef] [PubMed]
-
(2010)
Circulation
, vol.122
, pp. 920-927
-
-
Soon, E.1
Holmes, A.M.2
Treacy, C.M.3
Doughty, N.J.4
Southgate, L.5
Machado, R.D.6
Trembath, R.C.7
Jennings, S.8
Barker, L.9
Nicklin, P.10
-
122
-
-
84930893678
-
T-helper 17 cell polarization in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Hautefort, A., Girerd, B., Montani, D., Cohen-Kaminsky, S., Price, L., Lambrecht, B.N., Humbert, M., Perros, F. T-helper 17 cell polarization in pulmonary arterial hypertension. Chest 2015, 147, 1610–1620. [CrossRef] [PubMed]
-
(2015)
Chest
, vol.147
, pp. 1610-1620
-
-
Hautefort, A.1
Girerd, B.2
Montani, D.3
Cohen-Kaminsky, S.4
Price, L.5
Lambrecht, B.N.6
Humbert, M.7
Perros, F.8
-
123
-
-
33644824392
-
Increased plasma monocyte chemoattractant protein-1 level in idiopathic pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Itoh, T., Nagaya, N., Ishibashi-Ueda, H., Kyotani, S., Oya, H., Sakamaki, F., Kimura, H., Nakanishi, N. Increased plasma monocyte chemoattractant protein-1 level in idiopathic pulmonary arterial hypertension. Respirology 2006, 11, 158–163. [CrossRef] [PubMed]
-
(2006)
Respirology
, vol.11
, pp. 158-163
-
-
Itoh, T.1
Nagaya, N.2
Ishibashi-Ueda, H.3
Kyotani, S.4
Oya, H.5
Sakamaki, F.6
Kimura, H.7
Nakanishi, N.8
-
124
-
-
30144444546
-
Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice
-
[CrossRef] [PubMed]
-
Golembeski, S.M., West, J., Tada, Y., Fagan, K.A. Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice. Chest 2005, 128, 572S–573S. [CrossRef] [PubMed]
-
(2005)
Chest
, vol.128
, pp. 572S-573S
-
-
Golembeski, S.M.1
West, J.2
Tada, Y.3
Fagan, K.A.4
-
125
-
-
0028861014
-
Pulmonary hypertension in rats. 2. Role of interleukin-6
-
[CrossRef] [PubMed]
-
Miyata, M., Sakuma, F., Yoshimura, A., Ishikawa, H., Nishimaki, T., Kasukawa, R. Pulmonary hypertension in rats. 2. Role of interleukin-6. Int. Arch. Allergy Immunol. 1995, 108, 287–291. [CrossRef] [PubMed]
-
(1995)
Int. Arch. Allergy Immunol
, vol.108
, pp. 287-291
-
-
Miyata, M.1
Sakuma, F.2
Yoshimura, A.3
Ishikawa, H.4
Nishimaki, T.5
Kasukawa, R.6
-
126
-
-
59849118025
-
Interleukin-6 overexpression induces pulmonary hypertension
-
[CrossRef] [PubMed]
-
Steiner, M.K., Syrkina, O.L., Kolliputi, N., Mark, E.J., Hales, C.A., Waxman, A.B. Interleukin-6 overexpression induces pulmonary hypertension. Circ. Res. 2009, 104, 236–244. [CrossRef] [PubMed]
-
(2009)
Circ. Res
, vol.104
, pp. 236-244
-
-
Steiner, M.K.1
Syrkina, O.L.2
Kolliputi, N.3
Mark, E.J.4
Hales, C.A.5
Waxman, A.B.6
-
127
-
-
61549104663
-
Eddahibi, S. Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
-
[CrossRef] [PubMed]
-
Savale, L., Tu, L., Rideau, D., Izziki, M., Maitre, B., Adnot, S., Eddahibi, S. Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice. Respir. Res. 2009, 10, 6. [CrossRef] [PubMed]
-
(2009)
Respir. Res
, vol.10
, pp. 6
-
-
Savale, L.1
Tu, L.2
Rideau, D.3
Izziki, M.4
Maitre, B.5
Adnot, S.6
-
128
-
-
46749127004
-
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
-
[CrossRef] [PubMed]
-
Meira, L.B., Bugni, J.M., Green, S.L., Lee, C.-W., Pang, B., Borenshtein, D., Rickman, B.H., Rogers, A.B., Moroski-Erkul, C.A., McFaline, J.L., et al. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J. Clin. Investig. 2008, 118, 2516–2525. [CrossRef] [PubMed]
-
(2008)
J. Clin. Investig
, vol.118
, pp. 2516-2525
-
-
Meira, L.B.1
Bugni, J.M.2
Green, S.L.3
Lee, C.-W.4
Pang, B.5
Borenshtein, D.6
Rickman, B.H.7
Rogers, A.B.8
Moroski-Erkul, C.A.9
McFaline, J.L.10
-
129
-
-
17044417550
-
TNF-α induced DNA damage in primary murine hepatocytes
-
[CrossRef] [PubMed]
-
Wheelhouse, N.M., Chan, Y.-S., Gillies, S.E., Caldwell, H., Ross, J.A., Harrison, D.J., Prost, S.: TNF-α induced DNA damage in primary murine hepatocytes. Int. J. Mol. Med. 2003, 12, 889–894. [CrossRef] [PubMed]
-
(2003)
Int. J. Mol. Med
, vol.12
, pp. 889-894
-
-
Wheelhouse, N.M.1
Chan, Y.-S.2
Gillies, S.E.3
Caldwell, H.4
Ross, J.A.5
Harrison, D.J.6
Prost, S.7
-
130
-
-
0037453028
-
Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes
-
[CrossRef] [PubMed]
-
Suematsu, N., Tsutsui, H., Wen, J., Kang, D., Ikeuchi, M., Ide, T., Hayashidani, S., Shiomi, T., Kubota, T., Hamasaki, N., et al. Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes. Circulation 2003, 107, 1418–1423. [CrossRef] [PubMed]
-
(2003)
Circulation
, vol.107
, pp. 1418-1423
-
-
Suematsu, N.1
Tsutsui, H.2
Wen, J.3
Kang, D.4
Ikeuchi, M.5
Ide, T.6
Hayashidani, S.7
Shiomi, T.8
Kubota, T.9
Hamasaki, N.10
-
131
-
-
84866150897
-
Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention
-
[CrossRef] [PubMed]
-
Poltz, R., Naumann, M. Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention. BMC Syst. Biol. 2012, 6, 125. [CrossRef] [PubMed]
-
(2012)
BMC Syst. Biol
, vol.6
, pp. 125
-
-
Poltz, R.1
Naumann, M.2
-
132
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
[CrossRef] [PubMed]
-
Pikarsky, E., Porat, R.M., Stein, I., Abramovitch, R., Amit, S., Kasem, S., Gutkovich-Pyest, E., Urieli-Shoval, S., Galun, E., Ben-Neriah, Y. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004, 431, 461–466. [CrossRef] [PubMed]
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
Gutkovich-Pyest, E.7
Urieli-Shoval, S.8
Galun, E.9
Ben-Neriah, Y.10
-
133
-
-
84896322230
-
Interplay between DNA repair and inflammation, and the link to cancer
-
[CrossRef] [PubMed]
-
Kidane, D., Chae, W.J., Czochor, J., Eckert, K.A., Glazer, P.M., Bothwell, A.L.M., Sweasy, J.B. Interplay between DNA repair and inflammation, and the link to cancer. Crit. Rev. Biochem. Mol. Biol. 2014, 49, 116–139. [CrossRef] [PubMed]
-
(2014)
Crit. Rev. Biochem. Mol. Biol
, vol.49
, pp. 116-139
-
-
Kidane, D.1
Chae, W.J.2
Czochor, J.3
Eckert, K.A.4
Glazer, P.M.5
Bothwell, A.L.M.6
Sweasy, J.B.7
-
134
-
-
35648983903
-
Inflammation and cancer: An ancient link with novel potentials
-
[CrossRef] [PubMed]
-
Hussain, S.P., Harris, C.C. Inflammation and cancer: An ancient link with novel potentials. Int. J. Cancer 2007, 121, 2373–2380. [CrossRef] [PubMed]
-
(2007)
Int. J. Cancer
, vol.121
, pp. 2373-2380
-
-
Hussain, S.P.1
Harris, C.C.2
-
135
-
-
74049140048
-
Inflammation and cancer: Interweaving microRNA, free radical, cytokine and p53 pathways
-
[CrossRef] [PubMed]
-
Schetter, A.J., Heegaard, N.H.H., Harris, C.C. Inflammation and cancer: Interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 2010, 31, 37–49. [CrossRef] [PubMed]
-
(2010)
Carcinogenesis
, vol.31
, pp. 37-49
-
-
Schetter, A.J.1
Heegaard, N.H.H.2
Harris, C.C.3
-
136
-
-
84925934160
-
Inflammation-induced DNA damage and damage-induced inflammation: A vicious cycle
-
[CrossRef] [PubMed]
-
Pálmai-Pallag, T., Bachrati, C.Z.: Inflammation-induced DNA damage and damage-induced inflammation: A vicious cycle. Microbes Infect. Inst. Pasteur 2014, 16, 822–832. [CrossRef] [PubMed]
-
(2014)
Microbes Infect. Inst. Pasteur
, vol.16
, pp. 822-832
-
-
Pálmai-Pallag, T.1
Bachrati, C.Z.2
-
137
-
-
84946829704
-
DNA damage response (DDR) and senescence: Shuttled inflamma-miRNAs on the stage of inflamm-aging
-
[PubMed]
-
Olivieri, F., Albertini, M.C., Orciani, M., Ceka, A., Cricca, M., Procopio, A.D., Bonafè, M.: DNA damage response (DDR) and senescence: Shuttled inflamma-miRNAs on the stage of inflamm-aging. Oncotarget 2015, 6, 35509–35521.[PubMed]
-
(2015)
Oncotarget
, vol.6
, pp. 35509-35521
-
-
Olivieri, F.1
Albertini, M.C.2
Orciani, M.3
Ceka, A.4
Cricca, M.5
Procopio, A.D.6
Bonafè, M.7
-
138
-
-
84863104297
-
DNA damage induces the IL-6/STAT3 signaling pathway, which has anti-senescence and growth-promoting functions in human tumors
-
[CrossRef] [PubMed]
-
Yun, U.J., Park, S.E., Jo, Y.S., Kim, J., Shin, D.Y. DNA damage induces the IL-6/STAT3 signaling pathway, which has anti-senescence and growth-promoting functions in human tumors. Cancer Lett. 2012, 323, 155–160. [CrossRef] [PubMed]
-
(2012)
Cancer Lett
, vol.323
, pp. 155-160
-
-
Yun, U.J.1
Park, S.E.2
Jo, Y.S.3
Kim, J.4
Shin, D.Y.5
-
139
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
[CrossRef] [PubMed]
-
Grivennikov, S., Karin, E., Terzic, J., Mucida, D., Yu, G.-Y., Vallabhapurapu, S., Scheller, J., Rose-John, S., Cheroutre, H., Eckmann, L., et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 2009, 15, 103–113. [CrossRef] [PubMed]
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.-Y.5
Vallabhapurapu, S.6
Scheller, J.7
Rose-John, S.8
Cheroutre, H.9
Eckmann, L.10
-
140
-
-
58649100056
-
Inflammation and cancer: IL-6 and STAT3 complete the link
-
[CrossRef] [PubMed]
-
Bromberg, J., Wang, T.C. Inflammation and cancer: IL-6 and STAT3 complete the link. Cancer Cell 2009, 15, 79–80. [CrossRef] [PubMed]
-
(2009)
Cancer Cell
, vol.15
, pp. 79-80
-
-
Bromberg, J.1
Wang, T.C.2
-
141
-
-
33751227533
-
Pulmonary hypertension due to BMPR2 mutation: A new paradigm for tissue remodeling
-
[CrossRef] [PubMed]
-
Morrell, N.W. Pulmonary hypertension due to BMPR2 mutation: A new paradigm for tissue remodeling? Proc. Am. Thorac. Soc. 2006, 3, 680–686. [CrossRef] [PubMed]
-
(2006)
Proc. Am. Thorac. Soc
, vol.3
, pp. 680-686
-
-
Morrell, N.W.1
-
142
-
-
34447534205
-
Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle
-
[CrossRef] [PubMed]
-
Hagen, M., Fagan, K., Steudel, W., Carr, M., Lane, K., Rodman, D.M., West, J. Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 292, L1473–L1479. [CrossRef] [PubMed]
-
(2007)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.292
, pp. L1473-L1479
-
-
Hagen, M.1
Fagan, K.2
Steudel, W.3
Carr, M.4
Lane, K.5
Rodman, D.M.6
West, J.7
-
143
-
-
84943257033
-
Bone morphogenetic protein receptor type II and inflammation are bringing old concepts into the new pulmonary arterial hypertension world
-
[CrossRef] [PubMed]
-
Perros, F., Bonnet, S.: Bone morphogenetic protein receptor type II and inflammation are bringing old concepts into the new pulmonary arterial hypertension world. Am. J. Respir. Crit. Care Med. 2015, 192, 777–779. [CrossRef] [PubMed]
-
(2015)
Am. J. Respir. Crit. Care Med
, vol.192
, pp. 777-779
-
-
Perros, F.1
Bonnet, S.2
-
144
-
-
84943266030
-
Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Soon, E., Crosby, A., Southwood, M., Yang, P., Tajsic, T., Toshner, M., Appleby, S., Shanahan, C.M., Bloch, K.D., Pepke-Zaba, J., et al. Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2015, 192, 859–872. [CrossRef] [PubMed]
-
(2015)
Am. J. Respir. Crit. Care Med
, vol.192
, pp. 859-872
-
-
Soon, E.1
Crosby, A.2
Southwood, M.3
Yang, P.4
Tajsic, T.5
Toshner, M.6
Appleby, S.7
Shanahan, C.M.8
Bloch, K.D.9
Pepke-Zaba, J.10
-
145
-
-
84904260870
-
STAT3 signaling in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Paulin, R., Meloche, J., Bonnet, S. STAT3 signaling in pulmonary arterial hypertension. JAK-STAT 2012, 1, 223–233. [CrossRef] [PubMed]
-
(2012)
JAK-STAT
, vol.1
, pp. 223-233
-
-
Paulin, R.1
Meloche, J.2
Bonnet, S.3
-
146
-
-
46349109892
-
Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Perros, F., Montani, D., Dorfmüller, P., Durand-Gasselin, I., Tcherakian, C., Le Pavec, J., Mazmanian, M., Fadel, E., Mussot, S., Mercier, O., et al. Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2008, 178, 81–88. [CrossRef] [PubMed]
-
(2008)
Am. J. Respir. Crit. Care Med
, vol.178
, pp. 81-88
-
-
Perros, F.1
Montani, D.2
Dorfmüller, P.3
Durand-Gasselin, I.4
Tcherakian, C.5
Le Pavec, J.6
Mazmanian, M.7
Fadel, E.8
Mussot, S.9
Mercier, O.10
-
147
-
-
84891671846
-
Reactive oxygen species in pulmonary vascular remodeling
-
[PubMed]
-
Aggarwal, S., Gross, C.M., Sharma, S., Fineman, J.R., Black, S.M. Reactive oxygen species in pulmonary vascular remodeling. Compr. Physiol. 2013, 3, 1011–1034.[PubMed]
-
(2013)
Compr. Physiol
, vol.3
, pp. 1011-1034
-
-
Aggarwal, S.1
Gross, C.M.2
Sharma, S.3
Fineman, J.R.4
Black, S.M.5
-
148
-
-
1542511743
-
Oxidative stress in severe pulmonary hypertension
-
[CrossRef] [PubMed]
-
Bowers, R., Cool, C., Murphy, R.C., Tuder, R.M., Hopken, M.W., Flores, S.C., Voelkel, N.F. Oxidative stress in severe pulmonary hypertension. Am. J. Respir. Crit. Care Med. 2004, 169, 764–769. [CrossRef] [PubMed]
-
(2004)
Am. J. Respir. Crit. Care Med
, vol.169
, pp. 764-769
-
-
Bowers, R.1
Cool, C.2
Murphy, R.C.3
Tuder, R.M.4
Hopken, M.W.5
Flores, S.C.6
Voelkel, N.F.7
-
149
-
-
80053899412
-
Contribution of oxidative stress to pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Demarco, V.G., Whaley-Connell, A.T., Sowers, J.R., Habibi, J., Dellsperger, K.C. Contribution of oxidative stress to pulmonary arterial hypertension. World J. Cardiol. 2010, 2, 316–324. [CrossRef] [PubMed]
-
(2010)
World J. Cardiol
, vol.2
, pp. 316-324
-
-
Demarco, V.G.1
Whaley-Connell, A.T.2
Sowers, J.R.3
Habibi, J.4
Dellsperger, K.C.5
-
150
-
-
80052572916
-
Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension
-
[CrossRef] [PubMed]
-
Dorfmüller, P., Chaumais, M.-C., Giannakouli, M., Durand-Gasselin, I., Raymond, N., Fadel, E., Mercier, O., Charlotte, F., Montani, D., Simonneau, G., et al. Increased oxidative stress and severe arterial remodeling induced by permanent high-flow challenge in experimental pulmonary hypertension. Respir. Res. 2011, 12, 119. [CrossRef] [PubMed]
-
(2011)
Respir. Res
, vol.12
, pp. 119
-
-
Dorfmüller, P.1
Chaumais, M.-C.2
Giannakouli, M.3
Durand-Gasselin, I.4
Raymond, N.5
Fadel, E.6
Mercier, O.7
Charlotte, F.8
Montani, D.9
Simonneau, G.10
-
151
-
-
38649139122
-
Regulation of fibroblast growth factor-2 expression in pulmonary arterial smooth muscle cells involves increased reactive oxygen species generation
-
[CrossRef] [PubMed]
-
Black, S.M., DeVol, J.M., Wedgwood, S. Regulation of fibroblast growth factor-2 expression in pulmonary arterial smooth muscle cells involves increased reactive oxygen species generation. Am. J. Physiol. Cell Physiol. 2008, 294, C345–C354. [CrossRef] [PubMed]
-
(2008)
Am. J. Physiol. Cell Physiol
, vol.294
, pp. C345-C354
-
-
Black, S.M.1
Devol, J.M.2
Wedgwood, S.3
-
152
-
-
0027008295
-
2 increases expression of pulmonary artery endothelial cell platelet-derived growth factor mRNA
-
[PubMed]
-
2 increases expression of pulmonary artery endothelial cell platelet-derived growth factor mRNA. J. Appl. Physiol. 1992, 73, 2255–2262.[PubMed]
-
(1992)
J. Appl. Physiol
, vol.73
, pp. 2255-2262
-
-
Montisano, D.F.1
Mann, T.2
Spragg, R.G.3
-
153
-
-
0035195281
-
ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species
-
[PubMed]
-
Wedgwood, S., Dettman, R.W., Black, S.M. ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001, 281, L1058–1067.[PubMed]
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.281
, pp. L1058-L1067
-
-
Wedgwood, S.1
Dettman, R.W.2
Black, S.M.3
-
154
-
-
34247250752
-
NAD(P)H oxidases regulate HIF-2alpha protein expression
-
[CrossRef] [PubMed]
-
Block, K., Gorin, Y., Hoover, P., Williams, P., Chelmicki, T., Clark, R.A., Yoneda, T., Abboud, H.E. NAD(P)H oxidases regulate HIF-2alpha protein expression. J. Biol. Chem. 2007, 282, 8019–8026. [CrossRef] [PubMed]
-
(2007)
J. Biol. Chem
, vol.282
, pp. 8019-8026
-
-
Block, K.1
Gorin, Y.2
Hoover, P.3
Williams, P.4
Chelmicki, T.5
Clark, R.A.6
Yoneda, T.7
Abboud, H.E.8
-
155
-
-
0034682786
-
2 SENSING
-
[CrossRef] [PubMed]
-
2 SENSING. J. Biol. Chem. 2000, 275, 25130–25138. [CrossRef] [PubMed]
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
Wood, T.M.4
Melendez, J.A.5
Rodriguez, A.M.6
Schumacker, P.T.7
-
156
-
-
50949133897
-
Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2α mutation
-
[CrossRef] [PubMed]
-
Gale, D.P., Harten, S.K., Reid, C.D.L., Tuddenham, E.G.D., Maxwell, P.H. Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2α mutation. Blood 2008, 112, 919–921. [CrossRef] [PubMed]
-
(2008)
Blood
, vol.112
, pp. 919-921
-
-
Gale, D.P.1
Harten, S.K.2
Reid, C.D.L.3
Tuddenham, E.G.D.4
Maxwell, P.H.5
-
157
-
-
85047691081
-
Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
-
[CrossRef] [PubMed]
-
Brusselmans, K., Compernolle, V., Tjwa, M., Wiesener, M.S., Maxwell, P.H., Collen, D., Carmeliet, P. Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J. Clin. Investig. 2003, 111, 1519–1527. [CrossRef] [PubMed]
-
(2003)
J. Clin. Investig
, vol.111
, pp. 1519-1527
-
-
Brusselmans, K.1
Compernolle, V.2
Tjwa, M.3
Wiesener, M.S.4
Maxwell, P.H.5
Collen, D.6
Carmeliet, P.7
-
158
-
-
0034771241
-
Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells
-
[CrossRef] [PubMed]
-
Cheng, T.H., Shih, N.L., Chen, S.Y., Loh, S.H., Cheng, P.Y., Tsai, C.S., Liu, S.H., Wang, D.L., Chen, J.J. Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells. J. Mol. Cell. Cardiol. 2001, 33, 1805–1814. [CrossRef] [PubMed]
-
(2001)
J. Mol. Cell. Cardiol
, vol.33
, pp. 1805-1814
-
-
Cheng, T.H.1
Shih, N.L.2
Chen, S.Y.3
Loh, S.H.4
Cheng, P.Y.5
Tsai, C.S.6
Liu, S.H.7
Wang, D.L.8
Chen, J.J.9
-
159
-
-
0021170386
-
Oxygen metabolites stimulate thromboxane production and vasoconstriction in isolated saline-perfused rabbit lungs
-
[CrossRef] [PubMed]
-
Tate, R.M., Morris, H.G., Schroeder, W.R., Repine, J.E. Oxygen metabolites stimulate thromboxane production and vasoconstriction in isolated saline-perfused rabbit lungs. J. Clin. Investig. 1984, 74, 608–613. [CrossRef] [PubMed]
-
(1984)
J. Clin. Investig
, vol.74
, pp. 608-613
-
-
Tate, R.M.1
Morris, H.G.2
Schroeder, W.R.3
Repine, J.E.4
-
160
-
-
0024544697
-
Effects of reactive oxygen species on prostacyclin production in perinatal rat lung cells
-
[PubMed]
-
Lee, D.S., McCallum, E.A., Olson, D.M. Effects of reactive oxygen species on prostacyclin production in perinatal rat lung cells. J. Appl. Physiol. 1989, 66, 1321–1327.[PubMed]
-
(1989)
J. Appl. Physiol
, vol.66
, pp. 1321-1327
-
-
Lee, D.S.1
McCallum, E.A.2
Olson, D.M.3
-
161
-
-
84930753441
-
Oxidative stress in hypertension: Mechanisms and therapeutic opportunities
-
[CrossRef] [PubMed]
-
Brito, R., Castillo, G., González, J., Valls, N., Rodrigo, R. Oxidative stress in hypertension: Mechanisms and therapeutic opportunities. Exp. Clin. Endocrinol. Diabetes 2015, 123, 325–335. [CrossRef] [PubMed]
-
(2015)
Exp. Clin. Endocrinol. Diabetes
, vol.123
, pp. 325-335
-
-
Brito, R.1
Castillo, G.2
González, J.3
Valls, N.4
Rodrigo, R.5
-
162
-
-
0035001399
-
NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs
-
[PubMed]
-
Weissmann, N., Winterhalder, S., Nollen, M., Voswinckel, R., Quanz, K., Ghofrani, H.A., Schermuly, R.T., Seeger, W., Grimminger, F. NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001, 280, L638–L645.[PubMed]
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.280
, pp. L638-L645
-
-
Weissmann, N.1
Winterhalder, S.2
Nollen, M.3
Voswinckel, R.4
Quanz, K.5
Ghofrani, H.A.6
Schermuly, R.T.7
Seeger, W.8
Grimminger, F.9
-
163
-
-
0037131391
-
Mitochondrial Reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes
-
[CrossRef] [PubMed]
-
Waypa, G.B., Marks, J.D., Mack, M.M., Boriboun, C., Mungai, P.T., Schumacker, P.T. Mitochondrial Reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes. Circ. Res. 2002, 91, 719–726. [CrossRef] [PubMed]
-
(2002)
Circ. Res
, vol.91
, pp. 719-726
-
-
Waypa, G.B.1
Marks, J.D.2
Mack, M.M.3
Boriboun, C.4
Mungai, P.T.5
Schumacker, P.T.6
-
164
-
-
0035100461
-
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia
-
[PubMed]
-
Hoshikawa, Y., Ono, S., Suzuki, S., Tanita, T., Chida, M., Song, C., Noda, M., Tabata, T., Voelkel, N.F., Fujimura, S. Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia. J. Appl. Physiol. 2001, 90, 1299–1306.[PubMed]
-
(2001)
J. Appl. Physiol
, vol.90
, pp. 1299-1306
-
-
Hoshikawa, Y.1
Ono, S.2
Suzuki, S.3
Tanita, T.4
Chida, M.5
Song, C.6
Noda, M.7
Tabata, T.8
Voelkel, N.F.9
Fujimura, S.10
-
165
-
-
39149119639
-
Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats
-
[CrossRef] [PubMed]
-
Jankov, R.P., Kantores, C., Pan, J., Belik, J. Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats. Am. J. Physiol. 2008, 294, L233–L245. [CrossRef] [PubMed]
-
(2008)
Am. J. Physiol
, vol.294
, pp. L233-L245
-
-
Jankov, R.P.1
Kantores, C.2
Pan, J.3
Belik, J.4
-
166
-
-
84962245418
-
Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension
-
[CrossRef] [PubMed]
-
Rafikova, O., Rafikov, R., Kangath, A., Qu, N., Aggarwal, S., Sharma, S., Desai, J., Fields, T., Ludewig, B., Yuan, J.X.-Y., et al. Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension. Free Radic. Biol. Med. 2016. [CrossRef] [PubMed]
-
(2016)
Free Radic. Biol. Med
-
-
Rafikova, O.1
Rafikov, R.2
Kangath, A.3
Qu, N.4
Aggarwal, S.5
Sharma, S.6
Desai, J.7
Fields, T.8
Ludewig, B.9
Yuan, J.X.10
-
167
-
-
84922481952
-
Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure
-
[CrossRef] [PubMed]
-
Rawat, D.K., Alzoubi, A., Gupte, R., Chettimada, S., Watanabe, M., Kahn, A.G., Okada, T., McMurtry, I.F., Gupte, S.A.: Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure. Hypertension 2014, 64, 1266–1274. [CrossRef] [PubMed]
-
(2014)
Hypertension
, vol.64
, pp. 1266-1274
-
-
Rawat, D.K.1
Alzoubi, A.2
Gupte, R.3
Chettimada, S.4
Watanabe, M.5
Kahn, A.G.6
Okada, T.7
McMurtry, I.F.8
Gupte, S.A.9
-
168
-
-
33644798841
-
Hypoxic pulmonary hypertension: Role of superoxide and NADPH oxidase (gp91phox)
-
[CrossRef] [PubMed]
-
Liu, J.Q., Zelko, I.N., Erbynn, E.M., Sham, J.S.K., Folz, R.J. Hypoxic pulmonary hypertension: Role of superoxide and NADPH oxidase (gp91phox). Am. J. Physiol. Lung Cell. Mol. Physiol. 2006, 290, L2–L10. [CrossRef] [PubMed]
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.290
, pp. LL2-L10
-
-
Liu, J.Q.1
Zelko, I.N.2
Erbynn, E.M.3
Sham, J.S.K.4
Folz, R.J.5
-
169
-
-
2442619096
-
Adrenomedullin can protect against pulmonary vascular remodeling induced by hypoxia
-
[CrossRef] [PubMed]
-
Matsui, H., Shimosawa, T., Itakura, K., Guanqun, X., Ando, K., Fujita, T. Adrenomedullin can protect against pulmonary vascular remodeling induced by hypoxia. Circulation 2004, 109, 2246–2251. [CrossRef] [PubMed]
-
(2004)
Circulation
, vol.109
, pp. 2246-2251
-
-
Matsui, H.1
Shimosawa, T.2
Itakura, K.3
Guanqun, X.4
Ando, K.5
Fujita, T.6
-
170
-
-
84904718340
-
Fasudil reversed MCT-induced and chronic hypoxia-induced pulmonary hypertension by attenuating oxidative stress and inhibiting the expression of Trx1 and HIF-1α
-
[CrossRef] [PubMed]
-
Liu, M., Wang, Y., Zheng, L., Zheng, W., Dong, K., Chen, S., Zhang, B., Li, Z. Fasudil reversed MCT-induced and chronic hypoxia-induced pulmonary hypertension by attenuating oxidative stress and inhibiting the expression of Trx1 and HIF-1α. Respir. Physiol. Neurobiol. 2014, 201, 38–46. [CrossRef] [PubMed]
-
(2014)
Respir. Physiol. Neurobiol
, vol.201
, pp. 38-46
-
-
Liu, M.1
Wang, Y.2
Zheng, L.3
Zheng, W.4
Dong, K.5
Chen, S.6
Zhang, B.7
Li, Z.8
-
171
-
-
84894123701
-
Oxymatrine prevents hypoxia- and monocrotaline-induced pulmonary hypertension in rats
-
[CrossRef] [PubMed]
-
Zhang, B., Niu, W., Xu, D., Li, Y., Liu, M., Wang, Y., Luo, Y., Zhao, P., Liu, Y., Dong, M., et al. Oxymatrine prevents hypoxia- and monocrotaline-induced pulmonary hypertension in rats. Free Radic. Biol. Med. 2014, 69, 198–207. [CrossRef] [PubMed]
-
(2014)
Free Radic. Biol. Med
, vol.69
, pp. 198-207
-
-
Zhang, B.1
Niu, W.2
Xu, D.3
Li, Y.4
Liu, M.5
Wang, Y.6
Luo, Y.7
Zhao, P.8
Liu, Y.9
Dong, M.10
-
172
-
-
84904694156
-
N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats
-
[CrossRef] [PubMed]
-
Chaumais, M.-C., Ranchoux, B., Montani, D., Dorfmüller, P., Tu, L., Lecerf, F., Raymond, N., Guignabert, C., Price, L., Simonneau, G., et al. N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats. Respir. Res. 2014, 15, 65. [CrossRef] [PubMed]
-
(2014)
Respir. Res
, vol.15
, pp. 65
-
-
Chaumais, M.-C.1
Ranchoux, B.2
Montani, D.3
Dorfmüller, P.4
Tu, L.5
Lecerf, F.6
Raymond, N.7
Guignabert, C.8
Price, L.9
Simonneau, G.10
-
173
-
-
34548330008
-
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature
-
[CrossRef] [PubMed]
-
Mittal, M., Roth, M., König, P., Hofmann, S., Dony, E., Goyal, P., Selbitz, A.-C., Schermuly, R.T., Ghofrani, H.A., Kwapiszewska, G., et al. Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature. Circ. Res. 2007, 101, 258–267. [CrossRef] [PubMed]
-
(2007)
Circ. Res
, vol.101
, pp. 258-267
-
-
Mittal, M.1
Roth, M.2
König, P.3
Hofmann, S.4
Dony, E.5
Goyal, P.6
Selbitz, A.-C.7
Schermuly, R.T.8
Ghofrani, H.A.9
Kwapiszewska, G.10
-
174
-
-
0034458228
-
The NADPH oxidase of endothelial cells
-
[CrossRef] [PubMed]
-
Babior, B.M. The NADPH oxidase of endothelial cells. IUBMB Life 2000, 50, 267–269. [CrossRef] [PubMed]
-
(2000)
IUBMB Life
, vol.50
, pp. 267-269
-
-
Babior, B.M.1
-
175
-
-
0036710445
-
The superoxide-generating NADPH oxidase: Structural aspects and activation mechanism
-
[CrossRef] [PubMed]
-
Vignais, P.V. The superoxide-generating NADPH oxidase: Structural aspects and activation mechanism. Cell. Mol. Life Sci. 2002, 59, 1428–1459. [CrossRef] [PubMed]
-
(2002)
Cell. Mol. Life Sci
, vol.59
, pp. 1428-1459
-
-
Vignais, P.V.1
-
176
-
-
33745713119
-
Role of reactive oxygen species and gp91phox in endothelial dysfunction of pulmonary arteries induced by chronic hypoxia
-
[CrossRef] [PubMed]
-
Fresquet, F., Pourageaud, F., Leblais, V., Brandes, R.P., Savineau, J.-P., Marthan, R., Muller, B. Role of reactive oxygen species and gp91phox in endothelial dysfunction of pulmonary arteries induced by chronic hypoxia. Br. J. Pharmacol. 2006, 148, 714–723. [CrossRef] [PubMed]
-
(2006)
Br. J. Pharmacol
, vol.148
, pp. 714-723
-
-
Fresquet, F.1
Pourageaud, F.2
Leblais, V.3
Brandes, R.P.4
Savineau, J.-P.5
Marthan, R.6
Muller, B.7
-
177
-
-
0037067455
-
Increased NADPH oxidase activity, gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits
-
[CrossRef] [PubMed]
-
Paravicini, T.M., Gulluyan, L.M., Dusting, G.J., Drummond, G.R.: Increased NADPH oxidase activity, gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits. Circ. Res. 2002, 91, 54–61. [CrossRef] [PubMed]
-
(2002)
Circ. Res
, vol.91
, pp. 54-61
-
-
Paravicini, T.M.1
Gulluyan, L.M.2
Dusting, G.J.3
Drummond, G.R.4
-
178
-
-
49749100079
-
NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts
-
[CrossRef] [PubMed]
-
Li, S., Tabar, S.S., Malec, V., Eul, B.G., Klepetko, W., Weissmann, N., Grimminger, F., Seeger, W., Rose, F., Hänze, J. NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts. Antioxid. Redox Signal. 2008, 10, 1687–1698. [CrossRef] [PubMed]
-
(2008)
Antioxid. Redox Signal
, vol.10
, pp. 1687-1698
-
-
Li, S.1
Tabar, S.S.2
Malec, V.3
Eul, B.G.4
Klepetko, W.5
Weissmann, N.6
Grimminger, F.7
Seeger, W.8
Rose, F.9
Hänze, J.10
-
179
-
-
33646593852
-
Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells
-
[CrossRef] [PubMed]
-
Sturrock, A., Cahill, B., Norman, K., Huecksteadt, T.P., Hill, K., Sanders, K., Karwande, S.V., Stringham, J.C., Bull, D.A., Gleich, M., et al. Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 2006, 290, L661–L673. [CrossRef] [PubMed]
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.290
, pp. L661-L673
-
-
Sturrock, A.1
Cahill, B.2
Norman, K.3
Huecksteadt, T.P.4
Hill, K.5
Sanders, K.6
Karwande, S.V.7
Stringham, J.C.8
Bull, D.A.9
Gleich, M.10
-
180
-
-
70349157154
-
Growth factors and interleukin-6 across the lung circulation in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Selimovic, N., Bergh, C.-H., Andersson, B., Sakiniene, E., Carlsten, H., Rundqvist, B. Growth factors and interleukin-6 across the lung circulation in pulmonary hypertension. Eur. Respir. J. 2009, 34, 662–668. [CrossRef] [PubMed]
-
(2009)
Eur. Respir. J
, vol.34
, pp. 662-668
-
-
Selimovic, N.1
Bergh, C.-H.2
Ersson, B.3
Sakiniene, E.4
Carlsten, H.5
Rundqvist, B.6
-
181
-
-
0037399439
-
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
-
[CrossRef] [PubMed]
-
Landmesser, U., Dikalov, S., Price, S.R., McCann, L., Fukai, T., Holland, S.M., Mitch, W.E., Harrison, D.G. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J. Clin. Investig. 2003, 111, 1201–1209. [CrossRef] [PubMed]
-
(2003)
J. Clin. Investig
, vol.111
, pp. 1201-1209
-
-
Landmesser, U.1
Dikalov, S.2
Price, S.R.3
McCann, L.4
Fukai, T.5
Holland, S.M.6
Mitch, W.E.7
Harrison, D.G.8
-
182
-
-
21444441271
-
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease
-
[CrossRef] [PubMed]
-
Morris, C.R., Kato, G.J., Poljakovic, M., Wang, X., Blackwelder, W.C., Sachdev, V., Hazen, S.L., Vichinsky, E.P., Morris, S.M., Gladwin, M.T. Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. JAMA 2005, 294, 81–90. [CrossRef] [PubMed]
-
(2005)
JAMA
, vol.294
, pp. 81-90
-
-
Morris, C.R.1
Kato, G.J.2
Poljakovic, M.3
Wang, X.4
Blackwelder, W.C.5
Sachdev, V.6
Hazen, S.L.7
Vichinsky, E.P.8
Morris, S.M.9
Gladwin, M.T.10
-
183
-
-
21744452294
-
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension
-
[CrossRef]
-
Pullamsetti, S., Kiss, L., Ghofrani, H.A., Voswinckel, R., Haredza, P., Klepetko, W., Aigner, C., Fink, L., Muyal, J.P., Weissmann, N., et al. Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension. FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol. 2005, 19, 1175–1177. [CrossRef]
-
(2005)
FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol
, vol.19
, pp. 1175-1177
-
-
Pullamsetti, S.1
Kiss, L.2
Ghofrani, H.A.3
Voswinckel, R.4
Haredza, P.5
Klepetko, W.6
Aigner, C.7
Fink, L.8
Muyal, J.P.9
Weissmann, N.10
-
184
-
-
84904639338
-
MiR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia
-
[CrossRef] [PubMed]
-
Iannone, L., Zhao, L., Dubois, O., Duluc, L., Rhodes, C.J., Wharton, J., Wilkins, M.R., Leiper, J., Wojciak-Stothard, B. miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia. Biochem. J. 2014, 462, 103–112. [CrossRef] [PubMed]
-
(2014)
Biochem. J
, vol.462
, pp. 103-112
-
-
Iannone, L.1
Zhao, L.2
Dubois, O.3
Duluc, L.4
Rhodes, C.J.5
Wharton, J.6
Wilkins, M.R.7
Leiper, J.8
Wojciak-Stothard, B.9
-
185
-
-
78349279285
-
Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension
-
[CrossRef] [PubMed]
-
Li, X.-H., Peng, J., Tan, N., Wu, W.-H., Li, T.-T., Shi, R.-Z., Li, Y.-J. Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension. Vascul. Pharmacol. 2010, 53, 223–229. [CrossRef] [PubMed]
-
(2010)
Vascul. Pharmacol
, vol.53
, pp. 223-229
-
-
Li, X.-H.1
Peng, J.2
Tan, N.3
Wu, W.-H.4
Li, T.-T.5
Shi, R.-Z.6
Li, Y.-J.7
-
186
-
-
77954083190
-
Epigenetic attenuation of mitochondrial superoxide dismutase 2 (SOD2) in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Archer, S.L., Marsboom, G., Kim, G.H., Zhang, H.J., Toth, P.T., Svensson, E.C., Dyck, J.R.B., Gomberg-Maitland, M., Thébaud, B., Husain, A.N., et al. Epigenetic attenuation of mitochondrial superoxide dismutase 2 (SOD2) in pulmonary arterial hypertension. Circulation 2010, 121, 2661–2671. [CrossRef] [PubMed]
-
(2010)
Circulation
, vol.121
, pp. 2661-2671
-
-
Archer, S.L.1
Marsboom, G.2
Kim, G.H.3
Zhang, H.J.4
Toth, P.T.5
Svensson, E.C.6
Dyck, J.R.B.7
Gomberg-Maitland, M.8
Thébaud, B.9
Husain, A.N.10
-
187
-
-
84905441029
-
Oxidative-stress biomarkers in patients with pulmonary hypertension
-
[CrossRef] [PubMed]
-
Reis, G.S., Augusto, V.S., Silveira, A.P.C., Jordão, A.A., Baddini-Martinez, J., Poli Neto, O., Rodrigues, A.J., Evora, P.R.B. Oxidative-stress biomarkers in patients with pulmonary hypertension. Pulm. Circ. 2013, 3, 856–861. [CrossRef] [PubMed]
-
(2013)
Pulm. Circ
, vol.3
, pp. 856-861
-
-
Reis, G.S.1
Augusto, V.S.2
Silveira, A.P.C.3
Jordão, A.A.4
Baddini-Martinez, J.5
Poli Neto, O.6
Rodrigues, A.J.7
Evora, P.R.B.8
-
188
-
-
0035883591
-
Increased lipid peroxidation in patients with pulmonary hypertension
-
[CrossRef] [PubMed]
-
Cracowski, J.L., Cracowski, C., Bessard, G., Pepin, J.L., Bessard, J., Schwebel, C., Stanke-Labesque, F., Pison, C. Increased lipid peroxidation in patients with pulmonary hypertension. Am. J. Respir. Crit. Care Med. 2001, 164, 1038–1042. [CrossRef] [PubMed]
-
(2001)
Am. J. Respir. Crit. Care Med
, vol.164
, pp. 1038-1042
-
-
Cracowski, J.L.1
Cracowski, C.2
Bessard, G.3
Pepin, J.L.4
Bessard, J.5
Schwebel, C.6
Stanke-Labesque, F.7
Pison, C.8
-
189
-
-
84875924476
-
Reactive oxygen species and antioxidants in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Wong, C.-M., Bansal, G., Pavlickova, L., Marcocci, L., Suzuki, Y.J. Reactive oxygen species and antioxidants in pulmonary hypertension. Antioxid. Redox Signal. 2013, 18, 1789–1796. [CrossRef] [PubMed]
-
(2013)
Antioxid. Redox Signal
, vol.18
, pp. 1789-1796
-
-
Wong, C.-M.1
Bansal, G.2
Pavlickova, L.3
Marcocci, L.4
Suzuki, Y.J.5
-
190
-
-
84859644104
-
Reactive oxygen and nitrogen species in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Tabima, D.M., Frizzell, S., Gladwin, M.T. Reactive oxygen and nitrogen species in pulmonary hypertension. Free Radic. Biol. Med. 2012, 52, 1970–1986. [CrossRef] [PubMed]
-
(2012)
Free Radic. Biol. Med
, vol.52
, pp. 1970-1986
-
-
Tabima, D.M.1
Frizzell, S.2
Gladwin, M.T.3
-
191
-
-
75149192272
-
Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Crosswhite, P., Sun, Z. Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension. J. Hypertens. 2010, 28, 201–212. [CrossRef] [PubMed]
-
(2010)
J. Hypertens
, vol.28
, pp. 201-212
-
-
Crosswhite, P.1
Sun, Z.2
-
192
-
-
84893721705
-
Tracing the fates of site-specifically introduced DNA adducts in the human genome
-
[CrossRef] [PubMed]
-
Yasui, M., Kanemaru, Y., Kamoshita, N., Suzuki, T., Arakawa, T., Honma, M. Tracing the fates of site-specifically introduced DNA adducts in the human genome. DNA Repair 2014, 15, 11–20. [CrossRef] [PubMed]
-
(2014)
DNA Repair
, vol.15
, pp. 11-20
-
-
Yasui, M.1
Kanemaru, Y.2
Kamoshita, N.3
Suzuki, T.4
Arakawa, T.5
Honma, M.6
-
193
-
-
10744231806
-
Oxidative and alkylating damage in DNA
-
[CrossRef] [PubMed]
-
Martinez, G.R., Loureiro, A.P.M., Marques, S.A., Miyamoto, S., Yamaguchi, L.F., Onuki, J., Almeida, E.A., Garcia, C.C.M., Barbosa, L.F., Medeiros, M.H.G., et al. Oxidative and alkylating damage in DNA. Mutat. Res. 2003, 544, 115–127. [CrossRef] [PubMed]
-
(2003)
Mutat. Res
, vol.544
, pp. 115-127
-
-
Martinez, G.R.1
Loureiro, A.P.M.2
Marques, S.A.3
Miyamoto, S.4
Yamaguchi, L.F.5
Onuki, J.6
Almeida, E.A.7
Garcia, C.C.M.8
Barbosa, L.F.9
Medeiros, M.H.G.10
-
194
-
-
77950023207
-
Oxidative stress and oxidative damage in carcinogenesis
-
[CrossRef] [PubMed]
-
Klaunig, J.E., Kamendulis, L.M., Hocevar, B.A. Oxidative stress and oxidative damage in carcinogenesis. Toxicol. Pathol. 2010, 38, 96–109. [CrossRef] [PubMed]
-
(2010)
Toxicol. Pathol
, vol.38
, pp. 96-109
-
-
Klaunig, J.E.1
Kamendulis, L.M.2
Hocevar, B.A.3
-
195
-
-
0021986849
-
Aminorex and pulmonary hypertension
-
[PubMed]
-
Gurtner, H.P. Aminorex and pulmonary hypertension. A review. Cor et Vasa 1985, 27, 160–171.[PubMed]
-
(1985)
A Review. Cor Et Vasa
, vol.27
, pp. 160-171
-
-
Gurtner, H.P.1
-
196
-
-
0031718736
-
Primary pulmonary hypertension associated with the use of fenfluramine derivatives
-
[CrossRef] [PubMed]
-
Simonneau, G., Fartoukh, M., Sitbon, O., Humbert, M., Jagot, J.L., Hervé, P. Primary pulmonary hypertension associated with the use of fenfluramine derivatives. Chest 1998, 114, 195S–199S. [CrossRef] [PubMed]
-
(1998)
Chest
, vol.114
, pp. 195S-199S
-
-
Simonneau, G.1
Fartoukh, M.2
Sitbon, O.3
Humbert, M.4
Jagot, J.L.5
Hervé, P.6
-
197
-
-
0019369617
-
Pulmonary hypertension and fenfluramine
-
[CrossRef] [PubMed]
-
Douglas, J.G., Munro, J.F., Kitchin, A.H., Muir, A.L., Proudfoot, A.T.: Pulmonary hypertension and fenfluramine. Br. Med. J. Clin. Res. Ed. 1981, 283, 881–883. [CrossRef] [PubMed]
-
(1981)
Br. Med. J. Clin. Res. Ed
, vol.283
, pp. 881-883
-
-
Douglas, J.G.1
Munro, J.F.2
Kitchin, A.H.3
Muir, A.L.4
Proudfoot, A.T.5
-
198
-
-
84975819865
-
Pulmonary hypertension related to appetite suppressants
-
3rd ed., CRC Press: Boca Raton, FL, USA
-
Sitbon, O., Humbert, M., Simonneau, G. Pulmonary hypertension related to appetite suppressants. In Pulmonary Circulation: Diseases and Their Treatment, 3rd ed., CRC Press: Boca Raton, FL, USA, 2011.
-
(2011)
Pulmonary Circulation: Diseases and Their Treatment
-
-
Sitbon, O.1
Humbert, M.2
Simonneau, G.3
-
199
-
-
33845942152
-
Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?
-
[CrossRef] [PubMed]
-
Chin, K.M., Channick, R.N., Rubin, L.J. Is methamphetamine use associated with idiopathic pulmonary arterial hypertension? Chest 2006, 130, 1657–1663. [CrossRef] [PubMed]
-
(2006)
Chest
, vol.130
, pp. 1657-1663
-
-
Chin, K.M.1
Channick, R.N.2
Rubin, L.J.3
-
200
-
-
0027237417
-
Pulmonary hypertension associated with long-term inhalation of “crank” methamphetamine
-
[CrossRef] [PubMed]
-
Schaiberger, P.H., Kennedy, T.C., Miller, F.C., Gal, J., Petty, T.L. Pulmonary hypertension associated with long-term inhalation of “crank” methamphetamine. Chest 1993, 104, 614–616. [CrossRef] [PubMed]
-
(1993)
Chest
, vol.104
, pp. 614-616
-
-
Schaiberger, P.H.1
Kennedy, T.C.2
Miller, F.C.3
Gal, J.4
Petty, T.L.5
-
201
-
-
84883366292
-
Drug-induced pulmonary arterial hypertension: A recent outbreak
-
[CrossRef] [PubMed]
-
Montani, D., Seferian, A., Savale, L., Simonneau, G., Humbert, M. Drug-induced pulmonary arterial hypertension: A recent outbreak. Eur. Respir. Rev. 2013, 22, 244–250. [CrossRef] [PubMed]
-
(2013)
Eur. Respir. Rev
, vol.22
, pp. 244-250
-
-
Montani, D.1
Seferian, A.2
Savale, L.3
Simonneau, G.4
Humbert, M.5
-
202
-
-
84879793620
-
Effects of acute and chronic administration of fenproporex on DNA damage parameters in young and adult rats
-
[CrossRef] [PubMed]
-
Gonçalves, C.L., Rezin, G.T., Ferreira, G.K., Jeremias, I.C., Cardoso, M.R., Valvassori, S.S., Munhoz, B.J.P., Borges, G.D., Bristot, B.N., Leffa, D.D., et al. Effects of acute and chronic administration of fenproporex on DNA damage parameters in young and adult rats. Mol. Cell. Biochem. 2013, 380, 171–176. [CrossRef] [PubMed]
-
(2013)
Mol. Cell. Biochem
, vol.380
, pp. 171-176
-
-
Gonçalves, C.L.1
Rezin, G.T.2
Ferreira, G.K.3
Jeremias, I.C.4
Cardoso, M.R.5
Valvassori, S.S.6
Munhoz, B.J.P.7
Borges, G.D.8
Bristot, B.N.9
Leffa, D.D.10
-
203
-
-
71949091609
-
Single exposure to cocaine or ecstasy induces DNA damage in brain and other organs of mice
-
[CrossRef] [PubMed]
-
Alvarenga, T.A., Andersen, M.L., Ribeiro, D.A., Araujo, P., Hirotsu, C., Costa, J.L., Battisti, M.C., Tufik, S. Single exposure to cocaine or ecstasy induces DNA damage in brain and other organs of mice. Addict. Biol. 2010, 15, 96–99. [CrossRef] [PubMed]
-
(2010)
Addict. Biol
, vol.15
, pp. 96-99
-
-
Alvarenga, T.A.1
Ersen, M.L.2
Ribeiro, D.A.3
Araujo, P.4
Hirotsu, C.5
Costa, J.L.6
Battisti, M.C.7
Tufik, S.8
-
204
-
-
56349115455
-
Effects of mood stabilizers on DNA damage in an animal model of mania
-
[PubMed]
-
Andreazza, A.C., Kauer-Sant’Anna, M., Frey, B.N., Stertz, L., Zanotto, C., Ribeiro, L., Giasson, K., Valvassori, S.S., Réus, G.Z., Salvador, M., et al. Effects of mood stabilizers on DNA damage in an animal model of mania. J. Psychiatry Neurosci. 2008, 33, 516–524.[PubMed]
-
(2008)
J. Psychiatry Neurosci
, vol.33
, pp. 516-524
-
-
Andreazza, A.C.1
Kauer-Sant’anna, M.2
Frey, B.N.3
Stertz, L.4
Zanotto, C.5
Ribeiro, L.6
Giasson, K.7
Valvassori, S.S.8
Réus, G.Z.9
Salvador, M.10
-
205
-
-
0026683944
-
Clastogenic effect of fenfluramine in mice bone marrow cells in vivo
-
[CrossRef] [PubMed]
-
Agarwal, K., Mukherjee, A., Sharma, A., Sharma, R., Bhardwaj, K.R., Sen, S. Clastogenic effect of fenfluramine in mice bone marrow cells in vivo. Environ. Mol. Mutagen. 1992, 19, 323–326. [CrossRef] [PubMed]
-
(1992)
Environ. Mol. Mutagen
, vol.19
, pp. 323-326
-
-
Agarwal, K.1
Mukherjee, A.2
Sharma, A.3
Sharma, R.4
Bhardwaj, K.R.5
Sen, S.6
-
206
-
-
84930322627
-
Methamphetamine induces DNA damage in specific regions of the female rat brain
-
[CrossRef] [PubMed]
-
Johnson, Z., Venters, J., Guarraci, F.A., Zewail-Foote, M. Methamphetamine induces DNA damage in specific regions of the female rat brain. Clin. Exp. Pharmacol. Physiol. 2015, 42, 570–575. [CrossRef] [PubMed]
-
(2015)
Clin. Exp. Pharmacol. Physiol
, vol.42
, pp. 570-575
-
-
Johnson, Z.1
Venters, J.2
Guarraci, F.A.3
Zewail-Foote, M.4
-
207
-
-
33750715112
-
ATP-generating glycolytic substrates prevent N-nitrosofenfluramine-induced cytotoxicity in isolated rat hepatocytes
-
[CrossRef] [PubMed]
-
Nakagawa, Y., Tayama, S., Ogata, A., Suzuki, T., Ishii, H. ATP-generating glycolytic substrates prevent N-nitrosofenfluramine-induced cytotoxicity in isolated rat hepatocytes. Chem. Biol. Interact. 2006, 164, 93–101. [CrossRef] [PubMed]
-
(2006)
Chem. Biol. Interact
, vol.164
, pp. 93-101
-
-
Nakagawa, Y.1
Tayama, S.2
Ogata, A.3
Suzuki, T.4
Ishii, H.5
-
208
-
-
84953723708
-
Amphetamine exposure imbalanced antioxidant activity in the bivalve Dreissena polymorpha causing oxidative and genetic damage
-
[CrossRef] [PubMed]
-
Parolini, M., Magni, S., Castiglioni, S., Binelli, A. Amphetamine exposure imbalanced antioxidant activity in the bivalve Dreissena polymorpha causing oxidative and genetic damage. Chemosphere 2016, 144, 207–213. [CrossRef] [PubMed]
-
(2016)
Chemosphere
, vol.144
, pp. 207-213
-
-
Parolini, M.1
Magni, S.2
Castiglioni, S.3
Binelli, A.4
-
209
-
-
77749282863
-
An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex
-
[CrossRef] [PubMed]
-
Da Silva, C.J., dos Santos, J.E., Satie Takahashi, C. An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex. Hum. Exp. Toxicol. 2010, 29, 187–197. [CrossRef] [PubMed]
-
(2010)
Hum. Exp. Toxicol
, vol.29
, pp. 187-197
-
-
Da Silva, C.J.1
Dos Santos, J.E.2
Satie Takahashi, C.3
-
210
-
-
84884889978
-
Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse
-
[CrossRef] [PubMed]
-
Perfeito, R., Cunha-Oliveira, T., Rego, A.C. Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse. Free Radic. Biol. Med. 2013, 62, 186–201. [CrossRef] [PubMed]
-
(2013)
Free Radic. Biol. Med
, vol.62
, pp. 186-201
-
-
Perfeito, R.1
Cunha-Oliveira, T.2
Rego, A.C.3
-
211
-
-
0032517109
-
The appetite suppressant d-fenfluramine induces apoptosis in human serotonergic cells
-
[CrossRef] [PubMed]
-
Bengel, D., Isaacs, K.R., Heils, A., Lesch, K.P., Murphy, D.L. The appetite suppressant d-fenfluramine induces apoptosis in human serotonergic cells. Neuroreport 1998, 9, 2989–2993. [CrossRef] [PubMed]
-
(1998)
Neuroreport
, vol.9
, pp. 2989-2993
-
-
Bengel, D.1
Isaacs, K.R.2
Heils, A.3
Lesch, K.P.4
Murphy, D.L.5
-
212
-
-
25444451561
-
Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: Lessons for the future in pathogenesis
-
[CrossRef] [PubMed]
-
Eddahibi, S., Adnot, S. Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: Lessons for the future in pathogenesis. Respir. Res. 2002, 3, 9. [CrossRef] [PubMed]
-
(2002)
Respir. Res
, vol.3
, pp. 9
-
-
Eddahibi, S.1
Adnot, S.2
-
213
-
-
84966659553
-
Maternal use of selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn
-
[CrossRef] [PubMed]
-
Alwan, S., Bandoli, G., Chambers, C.D. Maternal use of selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. Clin. Pharmacol. Ther. 2016. [CrossRef] [PubMed]
-
(2016)
Clin. Pharmacol. Ther
-
-
Alwan, S.1
Bandoli, G.2
Chambers, C.D.3
-
214
-
-
36248944133
-
Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat
-
[CrossRef] [PubMed]
-
Fornaro, E., Li, D., Pan, J., Belik, J. Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat. Am. J. Respir. Crit. Care Med. 2007, 176, 1035–1040. [CrossRef] [PubMed]
-
(2007)
Am. J. Respir. Crit. Care Med
, vol.176
, pp. 1035-1040
-
-
Fornaro, E.1
Li, D.2
Pan, J.3
Belik, J.4
-
215
-
-
84881535681
-
Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Sadoughi, A., Roberts, K.E., Preston, I.R., Lai, G.P., McCollister, D.H., Farber, H.W., Hill, N.S. Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension. Chest 2013, 144, 531–541. [CrossRef] [PubMed]
-
(2013)
Chest
, vol.144
, pp. 531-541
-
-
Sadoughi, A.1
Roberts, K.E.2
Preston, I.R.3
Lai, G.P.4
McCollister, D.H.5
Farber, H.W.6
Hill, N.S.7
-
216
-
-
84856731450
-
Selective serotonin reuptake inhibitors and pulmonary arterial hypertension: A case-control study
-
[CrossRef] [PubMed]
-
Dhalla, I.A., Juurlink, D.N., Gomes, T., Granton, J.T., Zheng, H., Mamdani, M.M. Selective serotonin reuptake inhibitors and pulmonary arterial hypertension: A case-control study. Chest 2012, 141, 348–353. [CrossRef] [PubMed]
-
(2012)
Chest
, vol.141
, pp. 348-353
-
-
Dhalla, I.A.1
Juurlink, D.N.2
Gomes, T.3
Granton, J.T.4
Zheng, H.5
Mamdani, M.M.6
-
217
-
-
0034776773
-
Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
-
[CrossRef] [PubMed]
-
Eddahibi, S., Humbert, M., Fadel, E., Raffestin, B., Darmon, M., Capron, F., Simonneau, G., Dartevelle, P., Hamon, M., Adnot, S. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J. Clin. Investig. 2001, 108, 1141–1150. [CrossRef] [PubMed]
-
(2001)
J. Clin. Investig
, vol.108
, pp. 1141-1150
-
-
Eddahibi, S.1
Humbert, M.2
Fadel, E.3
Raffestin, B.4
Darmon, M.5
Capron, F.6
Simonneau, G.7
Dartevelle, P.8
Hamon, M.9
Adnot, S.10
-
218
-
-
0034096980
-
Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
-
[CrossRef] [PubMed]
-
Eddahibi, S., Hanoun, N., Lanfumey, L., Lesch, K.P., Raffestin, B., Hamon, M., Adnot, S. Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J. Clin. Investig. 2000, 105, 1555–1562. [CrossRef] [PubMed]
-
(2000)
J. Clin. Investig
, vol.105
, pp. 1555-1562
-
-
Eddahibi, S.1
Hanoun, N.2
Lanfumey, L.3
Lesch, K.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
-
219
-
-
84865020265
-
Genotoxic evaluation of selective serotonin-reuptake inhibitors by use of the somatic mutation and recombination test in Drosophila melanogaster
-
[CrossRef] [PubMed]
-
Gürbüzel, M., Oral, E., Kizilet, H., Halici, Z., Gulec, M.: Genotoxic evaluation of selective serotonin-reuptake inhibitors by use of the somatic mutation and recombination test in Drosophila melanogaster. Mutat. Res. 2012, 748, 17–20. [CrossRef] [PubMed]
-
(2012)
Mutat. Res
, vol.748
, pp. 17-20
-
-
Gürbüzel, M.1
Oral, E.2
Kizilet, H.3
Halici, Z.4
Gulec, M.5
-
220
-
-
79958828800
-
Fluoxetine affects antioxidant system and promotes apoptotic signaling inWistar rat liver
-
[CrossRef] [PubMed]
-
Djordjevic, J., Djordjevic, A., Adzic, M., Elaković, I., Matić, G., Radojcic, M.B. Fluoxetine affects antioxidant system and promotes apoptotic signaling inWistar rat liver. Eur. J. Pharmacol. 2011, 659, 61–66. [CrossRef] [PubMed]
-
(2011)
Eur. J. Pharmacol
, vol.659
, pp. 61-66
-
-
Djordjevic, J.1
Djordjevic, A.2
Adzic, M.3
Elaković, I.4
Matić, G.5
Radojcic, M.B.6
-
221
-
-
84878804122
-
Sister chromatid exchanges and sperm abnormalities produced by antidepressant drug fluoxetine in mouse treated in vivo
-
[PubMed]
-
Alzahrani, H.A.S. Sister chromatid exchanges and sperm abnormalities produced by antidepressant drug fluoxetine in mouse treated in vivo. Eur. Rev. Med. Pharmacol. Sci. 2012, 16, 2154–2161.[PubMed]
-
(2012)
Eur. Rev. Med. Pharmacol. Sci
, vol.16
, pp. 2154-2161
-
-
Alzahrani, H.A.S.1
-
222
-
-
84931039950
-
Effects of selective serotonin reuptake inhibitors on sperm and male fertility
-
Riggin, L., Koren, G. Effects of selective serotonin reuptake inhibitors on sperm and male fertility. Can. Fam. Physician 2015, 61, 529–530.
-
(2015)
Can. Fam. Physician
, vol.61
, pp. 529-530
-
-
Riggin, L.1
Koren, G.2
-
223
-
-
84872191874
-
Citalopram at the recommended human doses after long-term treatment is genotoxic for male germ cell
-
[CrossRef] [PubMed]
-
Attia, S.M., Bakheet, S.A. Citalopram at the recommended human doses after long-term treatment is genotoxic for male germ cell. Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc. 2013, 53, 281–285. [CrossRef] [PubMed]
-
(2013)
Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc
, vol.53
, pp. 281-285
-
-
Attia, S.M.1
Bakheet, S.A.2
-
224
-
-
77955587006
-
Adverse effect of paroxetine on sperm
-
[CrossRef] [PubMed]
-
Tanrikut, C., Feldman, A.S., Altemus, M., Paduch, D.A., Schlegel, P.N. Adverse effect of paroxetine on sperm. Fertil. Steril. 2010, 94, 1021–1026. [CrossRef] [PubMed]
-
(2010)
Fertil. Steril
, vol.94
, pp. 1021-1026
-
-
Tanrikut, C.1
Feldman, A.S.2
Altemus, M.3
Paduch, D.A.4
Schlegel, P.N.5
-
225
-
-
84919845550
-
The use of antidepressants and the risk of idiopathic pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Fox, B.D., Azoulay, L., Dell’Aniello, S., Langleben, D., Lapi, F., Benisty, J., Suissa, S. The use of antidepressants and the risk of idiopathic pulmonary arterial hypertension. Can. J. Cardiol. 2014, 30, 1633–1639. [CrossRef] [PubMed]
-
(2014)
Can. J. Cardiol
, vol.30
, pp. 1633-1639
-
-
Fox, B.D.1
Azoulay, L.2
Dell’Aniello, S.3
Langleben, D.4
Lapi, F.5
Benisty, J.6
Suissa, S.7
-
226
-
-
84922374295
-
Elevated level of DNA damage and impaired repair of oxidative DNA damage in patients with recurrent depressive disorder
-
Czarny, P., Kwiatkowski, D., Kacperska, D., Kawczyńska, D., Talarowska, M., Orzechowska, A., Bielecka-Kowalska, A., Szemraj, J., Gałecki, P., Śliwiński, T. Elevated level of DNA damage and impaired repair of oxidative DNA damage in patients with recurrent depressive disorder. Med. Sci. Monit. Int. Med. J. Exp. Clin. Res. 2015, 21, 412–418.
-
(2015)
Med. Sci. Monit. Int. Med. J. Exp. Clin. Res
, vol.21
, pp. 412-418
-
-
Czarny, P.1
Kwiatkowski, D.2
Kacperska, D.3
Kawczyńska, D.4
Talarowska, M.5
Orzechowska, A.6
Bielecka-Kowalska, A.7
Szemraj, J.8
Gałecki, P.9
Śliwiński, T.10
-
227
-
-
84920572199
-
Is depression associated with increased oxidative stress? A systematic review and meta-analysis
-
[CrossRef] [PubMed]
-
Black, C.N., Bot, M., Scheffer, P.G., Cuijpers, P., Penninx, B.W.J.H. Is depression associated with increased oxidative stress? A systematic review and meta-analysis. Psychoneuroendocrinology 2015, 51, 164–175. [CrossRef] [PubMed]
-
(2015)
Psychoneuroendocrinology
, vol.51
, pp. 164-175
-
-
Black, C.N.1
Bot, M.2
Scheffer, P.G.3
Cuijpers, P.4
Penninx, B.W.J.H.5
-
228
-
-
85052416341
-
-
John Libbey Eurotext: Paris, France
-
Lacave, R., Larsen, C.-J., Robert, J. Cancérologie Fondamentale, John Libbey Eurotext: Paris, France, 2005.
-
(2005)
Cancérologie Fondamentale
-
-
Lacave, R.1
Larsen, C.-J.2
Robert, J.3
-
229
-
-
84857126520
-
DNA damage induced by alkylating agents and repair pathways
-
[CrossRef] [PubMed]
-
Kondo, N., Takahashi, A., Ono, K., Ohnishi, T. DNA damage induced by alkylating agents and repair pathways. J. Nucleic Acids 2010, 2010, 543531. [CrossRef] [PubMed]
-
(2010)
J. Nucleic Acids
, vol.2010
-
-
Kondo, N.1
Takahashi, A.2
Ono, K.3
Ohnishi, T.4
-
230
-
-
84856233300
-
Balancing repair and tolerance of DNA damage caused by alkylating agents
-
[CrossRef] [PubMed]
-
Fu, D., Calvo, J.A., Samson, L.D. Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat. Rev. Cancer 2012, 12, 104–120. [CrossRef] [PubMed]
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 104-120
-
-
Fu, D.1
Calvo, J.A.2
Samson, L.D.3
-
231
-
-
0028839115
-
Toxicity of mitomycin C toward cultured pulmonary artery endothelium
-
[CrossRef] [PubMed]
-
Hoorn, C.M., Wagner, J.G., Petry, T.W., Roth, R.A. Toxicity of mitomycin C toward cultured pulmonary artery endothelium. Toxicol. Appl. Pharmacol. 1995, 130, 87–94. [CrossRef] [PubMed]
-
(1995)
Toxicol. Appl. Pharmacol
, vol.130
, pp. 87-94
-
-
Hoorn, C.M.1
Wagner, J.G.2
Petry, T.W.3
Roth, R.A.4
-
232
-
-
80755186917
-
Ultrastructurural picture of cyclophosphamide-induced damage to the liver
-
[CrossRef] [PubMed]
-
Lushnikova, E.L., Molodykh, O.P., Nepomnyashchikh, L.M., Bakulina, A.A., Sorokina, Y.A. Ultrastructurural picture of cyclophosphamide-induced damage to the liver. Bull. Exp. Biol. Med. 2011, 151, 751–756. [CrossRef] [PubMed]
-
(2011)
Bull. Exp. Biol. Med
, vol.151
, pp. 751-756
-
-
Lushnikova, E.L.1
Molodykh, O.P.2
Nepomnyashchikh, L.M.3
Bakulina, A.A.4
Sorokina, Y.A.5
-
233
-
-
84922311080
-
Chemotherapy-induced pulmonary hypertension: Role of alkylating agents
-
[CrossRef] [PubMed]
-
Ranchoux, B., Günther, S., Quarck, R., Chaumais, M.-C., Dorfmüller, P., Antigny, F., Dumas, S.J., Raymond, N., Lau, E., Savale, L., et al. Chemotherapy-induced pulmonary hypertension: Role of alkylating agents. Am. J. Pathol. 2015, 185, 356–371. [CrossRef] [PubMed]
-
(2015)
Am. J. Pathol
, vol.185
, pp. 356-371
-
-
Ranchoux, B.1
Günther, S.2
Quarck, R.3
Chaumais, M.-C.4
Dorfmüller, P.5
Antigny, F.6
Dumas, S.J.7
Raymond, N.8
Lau, E.9
Savale, L.10
-
234
-
-
84940417913
-
Mitomycin-induced pulmonary veno-occlusive disease: Evidence from human disease and animal models
-
[CrossRef] [PubMed]
-
Perros, F., Günther, S., Ranchoux, B., Godinas, L., Antigny, F., Chaumais, M.-C., Dorfmüller, P., Hautefort, A., Raymond, N., Savale, L., et al. Mitomycin-induced pulmonary veno-occlusive disease: Evidence from human disease and animal models. Circulation 2015, 132, 834–847. [CrossRef] [PubMed]
-
(2015)
Circulation
, vol.132
, pp. 834-847
-
-
Perros, F.1
Günther, S.2
Ranchoux, B.3
Godinas, L.4
Antigny, F.5
Chaumais, M.-C.6
Dorfmüller, P.7
Hautefort, A.8
Raymond, N.9
Savale, L.10
-
235
-
-
84969751421
-
Pulmonary veno-occlusive disease
-
[CrossRef] [PubMed]
-
Montani, D., Lau, E.M., Dorfmüller, P., Girerd, B., Jaïs, X., Savale, L., Perros, F., Nossent, E., Garcia, G., Parent, F., et al. Pulmonary veno-occlusive disease. Eur. Respir. J. 2016, 47, 1518–1534. [CrossRef] [PubMed]
-
(2016)
Eur. Respir. J
, vol.47
, pp. 1518-1534
-
-
Montani, D.1
Lau, E.M.2
Dorfmüller, P.3
Girerd, B.4
Jaïs, X.5
Savale, L.6
Perros, F.7
Nossent, E.8
Garcia, G.9
Parent, F.10
-
236
-
-
0031666337
-
Immunohistochemical detection of NAD(P)H:Quinone oxidoreductase in human lung and lung tumors
-
[PubMed]
-
Siegel, D., Franklin, W.A., Ross, D. Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors. Clin. Cancer Res. 1998, 4, 2065–2070.[PubMed]
-
(1998)
Clin. Cancer Res
, vol.4
, pp. 2065-2070
-
-
Siegel, D.1
Franklin, W.A.2
Ross, D.3
-
237
-
-
0022453121
-
Cyclophosphamide modulation of bronchoalveolar cellular populations and macrophage oxidative metabolism. Possible mechanisms of pulmonary pharmacotoxicity
-
[PubMed]
-
Cooper, J.A., Merrill, W.W., Reynolds, H.Y. Cyclophosphamide modulation of bronchoalveolar cellular populations and macrophage oxidative metabolism. Possible mechanisms of pulmonary pharmacotoxicity. Am. Rev. Respir. Dis. 1986, 134, 108–114.[PubMed]
-
(1986)
Am. Rev. Respir. Dis
, vol.134
, pp. 108-114
-
-
Cooper, J.A.1
Merrill, W.W.2
Reynolds, H.Y.3
-
238
-
-
1642368865
-
Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression
-
[CrossRef] [PubMed]
-
Hamano, Y., Sugimoto, H., Soubasakos, M.A., Kieran, M., Olsen, B.R., Lawler, J., Sudhakar, A., Kalluri, R. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res. 2004, 64, 1570–1574. [CrossRef] [PubMed]
-
(2004)
Cancer Res
, vol.64
, pp. 1570-1574
-
-
Hamano, Y.1
Sugimoto, H.2
Soubasakos, M.A.3
Kieran, M.4
Olsen, B.R.5
Lawler, J.6
Sudhakar, A.7
Kalluri, R.8
-
239
-
-
33344473537
-
Cyclophosphamide enhances TNF-α-induced apoptotic cell death in murine vascular endothelial cell
-
[CrossRef] [PubMed]
-
Ohtani, T., Nakamura, T., Toda, K.-I., Furukawa, F. Cyclophosphamide enhances TNF-α-induced apoptotic cell death in murine vascular endothelial cell. FEBS Lett. 2006, 580, 1597–1600. [CrossRef] [PubMed]
-
(2006)
FEBS Lett
, vol.580
, pp. 1597-1600
-
-
Ohtani, T.1
Nakamura, T.2
Toda, K.-I.3
Furukawa, F.4
-
240
-
-
0036767657
-
Glutathione depletion and oxidative stress
-
[CrossRef]
-
Mytilineou, C., Kramer, B.C., Yabut, J.A.: Glutathione depletion and oxidative stress. Parkinsonism Relat. Disord. 2002, 8, 385–387. [CrossRef]
-
(2002)
Parkinsonism Relat. Disord
, vol.8
, pp. 385-387
-
-
Mytilineou, C.1
Kramer, B.C.2
Yabut, J.A.3
-
241
-
-
4444259109
-
Glutathione S-transferase M1 polymorphism: A risk factor for hepatic venoocclusive disease in bone marrow transplantation
-
[CrossRef] [PubMed]
-
Srivastava, A., Poonkuzhali, B., Shaji, R.V., George, B., Mathews, V., Chandy, M., Krishnamoorthy, R. Glutathione S-transferase M1 polymorphism: A risk factor for hepatic venoocclusive disease in bone marrow transplantation. Blood 2004, 104, 1574–1577. [CrossRef] [PubMed]
-
(2004)
Blood
, vol.104
, pp. 1574-1577
-
-
Srivastava, A.1
Poonkuzhali, B.2
Shaji, R.V.3
George, B.4
Mathews, V.5
Chandy, M.6
Krishnamoorthy, R.7
-
242
-
-
0029809978
-
Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation
-
[CrossRef] [PubMed]
-
DeLeve, L.D.: Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation. Hepatology 1996, 24, 830–837. [CrossRef] [PubMed]
-
(1996)
Hepatology
, vol.24
, pp. 830-837
-
-
Deleve, L.D.1
-
243
-
-
84948968052
-
Occupational exposure to organic solvents: A risk factor for pulmonary veno-occlusive disease
-
[CrossRef] [PubMed]
-
Montani, D., Lau, E.M., Descatha, A., Jaïs, X., Savale, L., Andujar, P., Bensefa-Colas, L., Girerd, B., Zendah, I., Le Pavec, J., et al. Occupational exposure to organic solvents: A risk factor for pulmonary veno-occlusive disease. Eur. Respir. J. 2015, 46, 1721–1731. [CrossRef] [PubMed]
-
(2015)
Eur. Respir. J
, vol.46
, pp. 1721-1731
-
-
Montani, D.1
Lau, E.M.2
Descatha, A.3
Jaïs, X.4
Savale, L.5
Ujar, P.6
Bensefa-Colas, L.7
Girerd, B.8
Zendah, I.9
Le Pavec, J.10
-
244
-
-
40849084970
-
Possible involvement of oxidative stress in trichloroethylene-induced genotoxicity in human HepG2 cells
-
[CrossRef] [PubMed]
-
Hu, C., Jiang, L., Geng, C., Zhang, X., Cao, J., Zhong, L. Possible involvement of oxidative stress in trichloroethylene-induced genotoxicity in human HepG2 cells. Mutat. Res. 2008, 652, 88–94. [CrossRef] [PubMed]
-
(2008)
Mutat. Res
, vol.652
, pp. 88-94
-
-
Hu, C.1
Jiang, L.2
Geng, C.3
Zhang, X.4
Cao, J.5
Zhong, L.6
-
245
-
-
0026076103
-
Lung vascular injury from monocrotaline pyrrole, a putative hepatic metabolite
-
[PubMed]
-
Roth, R.A., Reindel, J.F. Lung vascular injury from monocrotaline pyrrole, a putative hepatic metabolite. Adv. Exp. Med. Biol. 1991, 283, 477–487.[PubMed]
-
(1991)
Adv. Exp. Med. Biol
, vol.283
, pp. 477-487
-
-
Roth, R.A.1
Reindel, J.F.2
-
246
-
-
0028261162
-
Release of an alkylating metabolite, dehydromonocrotaline, from the isolated liver perfused with the pyrrolizidine alkaloid, monocrotaline
-
[PubMed]
-
Yan, C.C., Huxtable, R.J. Release of an alkylating metabolite, dehydromonocrotaline, from the isolated liver perfused with the pyrrolizidine alkaloid, monocrotaline. Proc. West. Pharmacol. Soc. 1994, 37, 107–108.[PubMed]
-
(1994)
Proc. West. Pharmacol. Soc
, vol.37
, pp. 107-108
-
-
Yan, C.C.1
Huxtable, R.J.2
-
247
-
-
0025117978
-
Trapping and measurement of short-lived alkylating agents in a recirculating flow system
-
[CrossRef]
-
Mattocks, A.R., Jukes, R. Trapping and measurement of short-lived alkylating agents in a recirculating flow system. Chem. Biol. Interact. 1990, 76, 19–30. [CrossRef]
-
(1990)
Chem. Biol. Interact
, vol.76
, pp. 19-30
-
-
Mattocks, A.R.1
Jukes, R.2
-
248
-
-
84894382202
-
Role for DNA damage signaling in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Meloche, J., Pflieger, A., Vaillancourt, M., Paulin, R., Potus, F., Zervopoulos, S., Graydon, C., Courboulin, A., Breuils-Bonnet, S., Tremblay, E., et al. Role for DNA damage signaling in pulmonary arterial hypertension. Circulation 2014, 129, 786–797. [CrossRef] [PubMed]
-
(2014)
Circulation
, vol.129
, pp. 786-797
-
-
Meloche, J.1
Pflieger, A.2
Vaillancourt, M.3
Paulin, R.4
Potus, F.5
Zervopoulos, S.6
Graydon, C.7
Courboulin, A.8
Breuils-Bonnet, S.9
Tremblay, E.10
-
249
-
-
84941671128
-
MiR-223 reverses experimental pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Meloche, J., Le Guen, M., Potus, F., Vinck, J., Ranchoux, B., Johnson, I., Antigny, F., Tremblay, E., Breuils-Bonnet, S., Perros, F., et al. miR-223 reverses experimental pulmonary arterial hypertension. Am. J. Physiol. Cell Physiol. 2015, 309, C363–C372. [CrossRef] [PubMed]
-
(2015)
Am. J. Physiol. Cell Physiol
, vol.309
, pp. C363-C372
-
-
Meloche, J.1
Le Guen, M.2
Potus, F.3
Vinck, J.4
Ranchoux, B.5
Johnson, I.6
Antigny, F.7
Tremblay, E.8
Breuils-Bonnet, S.9
Perros, F.10
-
250
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
[CrossRef] [PubMed]
-
Zhong, Z., Wen, Z., Darnell, J.E. Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994, 264, 95–98. [CrossRef] [PubMed]
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell, J.E.3
-
251
-
-
84940503934
-
Bromodomain-containing protein 4: The epigenetic origin of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Meloche, J.; Potus, F.; Vaillancourt, M.; Bourgeois, A.; Johnson, I.; Deschamps, L.; Chabot, S.; Ruffenach, G.; Henry, S.; Breuils-Bonnet, S. et al. Bromodomain-containing protein 4: The epigenetic origin of pulmonary arterial hypertension. Circ. Res. 2015, 117, 525–535.[CrossRef] [PubMed]
-
(2015)
Circ. Res
, vol.117
, pp. 525-535
-
-
Meloche, J.1
Potus, F.2
Vaillancourt, M.3
Bourgeois, A.4
Johnson, I.5
Deschamps, L.6
Chabot, S.7
Ruffenach, G.8
Henry, S.9
Breuils-Bonnet, S.10
-
252
-
-
33845657443
-
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
-
[CrossRef] [PubMed]
-
Wang, M.; Wu, W.; Wu, W.; Rosidi, B.; Zhang, L.; Wang, H.; Iliakis, G. PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Res. 2006, 34, 6170–6182.[CrossRef] [PubMed]
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 6170-6182
-
-
Wang, M.1
Wu, W.2
Wu, W.3
Rosidi, B.4
Zhang, L.5
Wang, H.6
Iliakis, G.7
-
253
-
-
84896277262
-
Mechanisms of oncogenic chromosomal translocations
-
[CrossRef] [PubMed]
-
Byrne, M.; Wray, J.; Reinert, B.; Wu, Y.; Nickoloff, J.; Lee, S.-H.; Hromas, R.; Williamson, E. Mechanisms of oncogenic chromosomal translocations. Ann. N. Y. Acad. Sci. 2014, 1310, 89–97.[CrossRef] [PubMed]
-
(2014)
Ann. N. Y. Acad. Sci
, vol.1310
, pp. 89-97
-
-
Byrne, M.1
Wray, J.2
Reinert, B.3
Wu, Y.4
Nickoloff, J.5
Lee, S.-H.6
Hromas, R.7
Williamson, E.8
-
254
-
-
84880415836
-
PARP1 is required for chromosomal translocations
-
[CrossRef] [PubMed]
-
Wray, J.; Williamson, E.A.; Singh, S.B.; Wu, Y.; Cogle, C.R.; Weinstock, D.M.; Zhang, Y.; Lee, S.-H.; Zhou, D.; Shao, L. et al. PARP1 is required for chromosomal translocations. Blood 2013, 121, 4359–4365.[CrossRef] [PubMed]
-
(2013)
Blood
, vol.121
, pp. 4359-4365
-
-
Wray, J.1
Williamson, E.A.2
Singh, S.B.3
Wu, Y.4
Cogle, C.R.5
Weinstock, D.M.6
Zhang, Y.7
Lee, S.-H.8
Zhou, D.9
Shao, L.10
-
255
-
-
84903167737
-
Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining
-
[CrossRef] [PubMed]
-
Soni, A.; Siemann, M.; Grabos, M.; Murmann, T.; Pantelias, G.E.; Iliakis, G. Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining. Nucleic Acids Res. 2014, 42, 6380–6392.[CrossRef] [PubMed]
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 6380-6392
-
-
Soni, A.1
Siemann, M.2
Grabos, M.3
Murmann, T.4
Pantelias, G.E.5
Iliakis, G.6
-
257
-
-
84884194843
-
Nuclear survivin and its relationship to DNA damage repair genes in non-small cell lung cancer investigated using tissue array
-
[CrossRef]
-
Hu, S.; Qu, Y.; Xu, X.; Xu, Q.; Geng, J.; Xu, J. Nuclear survivin and its relationship to DNA damage repair genes in non-small cell lung cancer investigated using tissue array. PLoS ONE 2013, 8, e74161.[CrossRef]
-
(2013)
Plos ONE
, pp. 8
-
-
Hu, S.1
Qu, Y.2
Xu, X.3
Xu, Q.4
Geng, J.5
Xu, J.6
-
258
-
-
80355128997
-
Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Paulin, R.; Meloche, J.; Jacob, M.H.; Bisserier, M.; Courboulin, A.; Bonnet, S. Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension. Am. J. Physiol. Heart Circ. Physiol. 2011, 301, H1798–H1809.[CrossRef] [PubMed]
-
(2011)
Am. J. Physiol. Heart Circ. Physiol
, vol.301
, pp. H1798-H1809
-
-
Paulin, R.1
Meloche, J.2
Jacob, M.H.3
Bisserier, M.4
Courboulin, A.5
Bonnet, S.6
-
259
-
-
20444483234
-
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
McMurtry, M.S.; Archer, S.L.; Altieri, D.C.; Bonnet, S.; Haromy, A.; Harry, G.; Bonnet, S.; Puttagunta, L.; Michelakis, E.D. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J. Clin. Investig. 2005, 115, 1479–1491.[CrossRef] [PubMed]
-
(2005)
J. Clin. Investig
, vol.115
, pp. 1479-1491
-
-
McMurtry, M.S.1
Archer, S.L.2
Altieri, D.C.3
Bonnet, S.4
Haromy, A.5
Harry, G.6
Bonnet, S.7
Puttagunta, L.8
Michelakis, E.D.9
-
260
-
-
84901784829
-
Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Li, M.; Vattulainen, S.; Aho, J.; Orcholski, M.; Rojas, V.; Yuan, K.; Helenius, M.; Taimen, P.; Myllykangas, S.; de Jesus Perez, V.; et al. Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension. Am. J. Respir. Cell Mol. Biol. 2014, 50, 1118–1128.[CrossRef] [PubMed]
-
(2014)
Am. J. Respir. Cell Mol. Biol
, vol.50
, pp. 1118-1128
-
-
Li, M.1
Vattulainen, S.2
Aho, J.3
Orcholski, M.4
Rojas, V.5
Yuan, K.6
Helenius, M.7
Taimen, P.8
Myllykangas, S.9
de Jesus Perez, V.10
-
261
-
-
84901047991
-
Whole-exome sequencing reveals topbp1 as a novel gene in idiopathic pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
De Jesus Perez, V.A.; Yuan, K.; Lyuksyutova, M.A.; Dewey, F.; Orcholski, M.E.; Shuffle, E.M.; Mathur, M.; Yancy, L.; Rojas, V.; Li, C.G. et al. Whole-exome sequencing reveals topbp1 as a novel gene in idiopathic pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 2014, 189, 1260–1272.[CrossRef] [PubMed]
-
(2014)
Am. J. Respir. Crit. Care Med
, vol.189
, pp. 1260-1272
-
-
de Jesus Perez, V.A.1
Yuan, K.2
Lyuksyutova, M.A.3
Dewey, F.4
Orcholski, M.E.5
Shuffle, E.M.6
Mathur, M.7
Yancy, L.8
Rojas, V.9
Li, C.G.10
-
262
-
-
84861572426
-
Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors
-
[CrossRef] [PubMed]
-
Lee, Y.; Katyal, S.; Downing, S.M.; Zhao, J.; Russell, H.R.; McKinnon, P.J. Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors. Nat. Neurosci. 2012, 15, 819–826.[CrossRef] [PubMed]
-
(2012)
Nat. Neurosci
, vol.15
, pp. 819-826
-
-
Lee, Y.1
Katyal, S.2
Downing, S.M.3
Zhao, J.4
Russell, H.R.5
McKinnon, P.J.6
-
263
-
-
0036134979
-
A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival
-
[CrossRef] [PubMed]
-
Yamane, K.; Wu, X.; Chen, J. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival. Mol. Cell. Biol. 2002, 22, 555–566.[CrossRef] [PubMed]
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 555-566
-
-
Yamane, K.1
Wu, X.2
Chen, J.3
-
264
-
-
0242456024
-
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response
-
[CrossRef] [PubMed]
-
Mäkiniemi, M.; Hillukkala, T.; Tuusa, J.; Reini, K.; Vaara, M.; Huang, D.; Pospiech, H.; Majuri, I.; Westerling, T.; Mäkelä, T.P.; et al. BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J. Biol. Chem. 2001, 276, 30399–30406.[CrossRef] [PubMed]
-
(2001)
J. Biol. Chem
, vol.276
, pp. 30399-30406
-
-
Mäkiniemi, M.1
Hillukkala, T.2
Tuusa, J.3
Reini, K.4
Vaara, M.5
Huang, D.6
Pospiech, H.7
Majuri, I.8
Westerling, T.9
Mäkelä, T.P.10
-
265
-
-
84965085545
-
Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases
-
[CrossRef] [PubMed]
-
Ngo, J.; Matsuyama, M.; Kim, C.; Poventud-Fuentes, I.; Bates, A.; Siedlak, S.L.; Lee, H.; Doughman, Y.Q.; Watanabe, M.; Liner, A. et al. Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. Cell Death Dis. 2015, 6, e1706.[CrossRef] [PubMed]
-
(2015)
Cell Death Dis
, pp. 6
-
-
Ngo, J.1
Matsuyama, M.2
Kim, C.3
Poventud-Fuentes, I.4
Bates, A.5
Siedlak, S.L.6
Lee, H.7
Doughman, Y.Q.8
Watanabe, M.9
Liner, A.10
-
266
-
-
84938718311
-
Inactivation of p53 is sufficient to induce development of pulmonary hypertension in rats
-
[CrossRef] [PubMed]
-
Jacquin, S.; Rincheval, V.; Mignotte, B.; Richard, S.; Humbert, M.; Mercier, O.; Londoño-Vallejo, A.; Fadel, E.; Eddahibi, S. Inactivation of p53 is sufficient to induce development of pulmonary hypertension in rats. PLoS ONE 2015, 10, e0131940.[CrossRef] [PubMed]
-
(2015)
Plos ONE
, pp. 10
-
-
Jacquin, S.1
Rincheval, V.2
Mignotte, B.3
Richard, S.4
Humbert, M.5
Mercier, O.6
Londoño-Vallejo, A.7
Fadel, E.8
Eddahibi, S.9
-
267
-
-
79955772507
-
P53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice
-
[CrossRef] [PubMed]
-
Mizuno, S.; Bogaard, H.J.; Kraskauskas, D.; Alhussaini, A.; Gomez-Arroyo, J.; Voelkel, N.F.; Ishizaki, T. p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 2011, 300, L753–L761.[CrossRef] [PubMed]
-
(2011)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.300
, pp. L753-L761
-
-
Mizuno, S.1
Bogaard, H.J.2
Kraskauskas, D.3
Alhussaini, A.4
Gomez-Arroyo, J.5
Voelkel, N.F.6
Ishizaki, T.7
-
268
-
-
84876577725
-
Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension
-
[CrossRef] [PubMed]
-
Mouraret, N.; Marcos, E.; Abid, S.; Gary-Bobo, G.; Saker, M.; Houssaini, A.; Dubois-Rande, J.-L.; Boyer, L.; Boczkowski, J.; Derumeaux, G. et al. Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension. Circulation 2013, 127, 1664–1676.[CrossRef] [PubMed]
-
(2013)
Circulation
, vol.127
, pp. 1664-1676
-
-
Mouraret, N.1
Marcos, E.2
Abid, S.3
Gary-Bobo, G.4
Saker, M.5
Houssaini, A.6
Dubois-Rande, J.-L.7
Boyer, L.8
Boczkowski, J.9
Derumeaux, G.10
-
269
-
-
84975828484
-
DNA damage at the dawn of micro-RNA pathway impairment in pulmonary arterial hypertension
-
[CrossRef]
-
Potus, F.; LeGuen, M.; Provencher, S.; Meloche, J.; Bonnet, S. DNA damage at the dawn of micro-RNA pathway impairment in pulmonary arterial hypertension. RNA Dis. 2015, 2.[CrossRef]
-
(2015)
RNA Dis
, pp. 2
-
-
Potus, F.1
Leguen, M.2
Provencher, S.3
Meloche, J.4
Bonnet, S.5
-
270
-
-
84951569500
-
MicroRNA networks in pulmonary arterial hypertension: Share mechanisms with cancer
-
[CrossRef] [PubMed]
-
Courboulin, A.; Ranchoux, B.; Cohen-Kaminsky, S.; Perros, F.; Bonnet, S. MicroRNA networks in pulmonary arterial hypertension: Share mechanisms with cancer? Curr. Opin. Oncol. 2016, 28, 72–82.[CrossRef] [PubMed]
-
(2016)
Curr. Opin. Oncol
, vol.28
, pp. 72-82
-
-
Courboulin, A.1
Ranchoux, B.2
Cohen-Kaminsky, S.3
Perros, F.4
Bonnet, S.5
-
271
-
-
84960194831
-
Nuclear DNA damage signalling to mitochondria in ageing
-
[CrossRef] [PubMed]
-
Fang, E.F.; Scheibye-Knudsen, M.; Chua, K.F.; Mattson, M.P.; Croteau, D.L.; Bohr, V.A. Nuclear DNA damage signalling to mitochondria in ageing. Nat. Rev. Mol. Cell Biol. 2016.[CrossRef] [PubMed]
-
(2016)
Nat. Rev. Mol. Cell Biol
-
-
Fang, E.F.1
Scheibye-Knudsen, M.2
Chua, K.F.3
Mattson, M.P.4
Croteau, D.L.5
Bohr, V.A.6
-
272
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
[CrossRef] [PubMed]
-
King, A.; Selak, M.A.; Gottlieb, E. Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer. Oncogene 2006, 25, 4675–4682.[CrossRef] [PubMed]
-
(2006)
Oncogene
, vol.25
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
273
-
-
84892404204
-
Mitochondrial dysfunction in cancer
-
[CrossRef] [PubMed]
-
Boland, M.L.; Chourasia, A.H.; Macleod, K.F. Mitochondrial dysfunction in cancer. Front. Oncol. 2013, 3, 292.[CrossRef] [PubMed]
-
(2013)
Front. Oncol
, vol.3
, pp. 292
-
-
Boland, M.L.1
Chourasia, A.H.2
Macleod, K.F.3
-
274
-
-
84891679916
-
Targeting mitochondrial dysfunction in lung diseases: Emphasis on mitophagy
-
[CrossRef] [PubMed]
-
Sureshbabu, A.; Bhandari, V. Targeting mitochondrial dysfunction in lung diseases: Emphasis on mitophagy. Front. Physiol. 2013, 4.[CrossRef] [PubMed]
-
(2013)
Front. Physiol
, pp. 4
-
-
Sureshbabu, A.1
Bhandari, V.2
-
275
-
-
84904321037
-
Mitochondria, endothelial cell function, and vascular diseases
-
[CrossRef] [PubMed]
-
Tang, X.; Luo, Y.-X.; Chen, H.-Z.; Liu, D.-P. Mitochondria, endothelial cell function, and vascular diseases. Front. Physiol. 2014, 5.[CrossRef] [PubMed]
-
(2014)
Front. Physiol
, pp. 5
-
-
Tang, X.1
Luo, Y.-X.2
Chen, H.-Z.3
Liu, D.-P.4
-
276
-
-
33846614655
-
Alterations of cellular bioenergetics in pulmonary artery endothelial cells
-
[CrossRef] [PubMed]
-
Xu, W.; Koeck, T.; Lara, A.R.; Neumann, D.; DiFilippo, F.P.; Koo, M.; Janocha, A.J.; Masri, F.A.; Arroliga, A.C.; Jennings, C. et al. Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc. Natl. Acad. Sci. USA 2007, 104, 1342–1347.[CrossRef] [PubMed]
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1342-1347
-
-
Xu, W.1
Koeck, T.2
Lara, A.R.3
Neumann, D.4
Difilippo, F.P.5
Koo, M.6
Janocha, A.J.7
Masri, F.A.8
Arroliga, A.C.9
Jennings, C.10
-
277
-
-
84873681470
-
Mitochondria in vascular health and disease
-
[CrossRef] [PubMed]
-
Dromparis, P.; Michelakis, E.D. Mitochondria in vascular health and disease. Annu. Rev. Physiol. 2013, 75, 95–126.[CrossRef] [PubMed]
-
(2013)
Annu. Rev. Physiol
, vol.75
, pp. 95-126
-
-
Dromparis, P.1
Michelakis, E.D.2
-
278
-
-
78149409004
-
The role of mitochondria in pulmonary vascular remodeling
-
[CrossRef] [PubMed]
-
Dromparis, P.; Sutendra, G.; Michelakis, E.D. The role of mitochondria in pulmonary vascular remodeling. J. Mol. Med. 2010, 88, 1003–1010.[CrossRef] [PubMed]
-
(2010)
J. Mol. Med
, vol.88
, pp. 1003-1010
-
-
Dromparis, P.1
Sutendra, G.2
Michelakis, E.D.3
-
279
-
-
33645770953
-
Mitochondria as signaling organelles in the vascular endothelium
-
[CrossRef] [PubMed]
-
Quintero, M.; Colombo, S.L.; Godfrey, A.; Moncada, S. Mitochondria as signaling organelles in the vascular endothelium. Proc. Natl. Acad. Sci. USA 2006, 103, 5379–5384.[CrossRef] [PubMed]
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 5379-5384
-
-
Quintero, M.1
Colombo, S.L.2
Godfrey, A.3
Moncada, S.4
-
280
-
-
84876347779
-
Mitochondria and Endothelial Function
-
[CrossRef] [PubMed]
-
Kluge, M.A.; Fetterman, J.L.; Vita, J.A. Mitochondria and Endothelial Function. Circ. Res. 2013, 112, 1171–1188.[CrossRef] [PubMed]
-
(2013)
Circ. Res
, vol.112
, pp. 1171-1188
-
-
Kluge, M.A.1
Fetterman, J.L.2
Vita, J.A.3
-
281
-
-
67349086630
-
The mitochondrial p53 pathway
-
[CrossRef] [PubMed]
-
Vaseva, A.V.; Moll, U.M. The mitochondrial p53 pathway. Biochim. Biophys. Acta Bioenerg. 2009, 1787, 414–420.[CrossRef] [PubMed]
-
(2009)
Biochim. Biophys. Acta Bioenerg
, vol.1787
, pp. 414-420
-
-
Vaseva, A.V.1
Moll, U.M.2
-
282
-
-
33745155785
-
An abnormal mitochondrial–hypoxia inducible factor-1α–Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats similarities to human pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Bonnet, S.; Michelakis, E.D.; Porter, C.J.; Andrade-Navarro, M.A.; Thébaud, B.; Bonnet, S.; Haromy, A.; Harry, G.; Moudgil, R.; McMurtry, M.S. et al. An abnormal mitochondrial–hypoxia inducible factor-1α–Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats similarities to human pulmonary arterial hypertension. Circulation 2006, 113, 2630–2641.[CrossRef] [PubMed]
-
(2006)
Circulation
, vol.113
, pp. 2630-2641
-
-
Bonnet, S.1
Michelakis, E.D.2
Porter, C.J.3
Andrade-Navarro, M.A.4
Thébaud, B.5
Bonnet, S.6
Haromy, A.7
Harry, G.8
Moudgil, R.9
McMurtry, M.S.10
-
283
-
-
84902968590
-
The metabolic theory of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Paulin, R.; Michelakis, E.D. The metabolic theory of pulmonary arterial hypertension. Circ. Res. 2014, 115, 148–164.[CrossRef] [PubMed]
-
(2014)
Circ. Res
, vol.115
, pp. 148-164
-
-
Paulin, R.1
Michelakis, E.D.2
-
284
-
-
79959464127
-
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Sutendra, G.; Dromparis, P.; Wright, P.; Bonnet, S.; Haromy, A.; Hao, Z.; McMurtry, M.S.; Michalak, M.; Vance, J.E.; Sessa, W.C.; et al. The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Sci. Transl. Med. 2011, 3, 88ra55.[CrossRef] [PubMed]
-
(2011)
Sci. Transl. Med
, vol.3
-
-
Sutendra, G.1
Dromparis, P.2
Wright, P.3
Bonnet, S.4
Haromy, A.5
Hao, Z.6
McMurtry, M.S.7
Michalak, M.8
Vance, J.E.9
Sessa, W.C.10
-
285
-
-
84872082742
-
Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Dromparis, P.; Paulin, R.; Stenson, T.H.; Haromy, A.; Sutendra, G.; Michelakis, E.D. Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension. Circulation 2013, 127, 115–125.[CrossRef] [PubMed]
-
(2013)
Circulation
, vol.127
, pp. 115-125
-
-
Dromparis, P.1
Paulin, R.2
Stenson, T.H.3
Haromy, A.4
Sutendra, G.5
Michelakis, E.D.6
-
286
-
-
84880735860
-
Metabolic dysfunction in pulmonary hypertension: The expanding relevance of the Warburg effect
-
[CrossRef] [PubMed]
-
Cottrill, K.A.; Chan, S.Y. Metabolic dysfunction in pulmonary hypertension: The expanding relevance of the Warburg effect. Eur. J. Clin. Investig. 2013, 43, 855–865.[CrossRef] [PubMed]
-
(2013)
Eur. J. Clin. Investig
, vol.43
, pp. 855-865
-
-
Cottrill, K.A.1
Chan, S.Y.2
-
287
-
-
84959213145
-
Potassium-channel subfamily k-member 3 (KCNK3) contributes to the development of pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Antigny, F.; Hautefort, A.; Meloche, J.; Belacel-Ouari, M.; Manoury, B.; Rucker-Martin, C.; Péchoux, C.; Potus, F.; Nadeau, V.; Tremblay, E. et al. Potassium-channel subfamily k-member 3 (KCNK3) contributes to the development of pulmonary arterial hypertension. Circulation 2016.[CrossRef] [PubMed]
-
(2016)
Circulation
-
-
Antigny, F.1
Hautefort, A.2
Meloche, J.3
Belacel-Ouari, M.4
Manoury, B.5
Rucker-Martin, C.6
Péchoux, C.7
Potus, F.8
Nadeau, V.9
Tremblay, E.10
-
288
-
-
84943236265
-
Potassium channels in pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Boucherat, O.; Chabot, S.; Antigny, F.; Perros, F.; Provencher, S.; Bonnet, S. Potassium channels in pulmonary arterial hypertension. Eur. Respir. J. 2015, 46, 1167–1177.[CrossRef] [PubMed]
-
(2015)
Eur. Respir. J
, vol.46
, pp. 1167-1177
-
-
Boucherat, O.1
Chabot, S.2
Antigny, F.3
Perros, F.4
Provencher, S.5
Bonnet, S.6
-
289
-
-
6344257102
-
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
-
[CrossRef] [PubMed]
-
McMurtry, M.S.; Bonnet, S.; Wu, X.; Dyck, J.R.B.; Haromy, A.; Hashimoto, K.; Michelakis, E.D. Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ. Res. 2004, 95, 830–840.[CrossRef] [PubMed]
-
(2004)
Circ. Res
, vol.95
, pp. 830-840
-
-
McMurtry, M.S.1
Bonnet, S.2
Wu, X.3
Dyck, J.R.B.4
Haromy, A.5
Hashimoto, K.6
Michelakis, E.D.7
-
290
-
-
0037080541
-
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels
-
[CrossRef] [PubMed]
-
Michelakis, E.D.; McMurtry, M.S.; Wu, X.-C.; Dyck, J.R.B.; Moudgil, R.; Hopkins, T.A.; Lopaschuk, G.D.; Puttagunta, L.; Waite, R.; Archer, S.L. Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels. Circulation 2002, 105, 244–250.[CrossRef] [PubMed]
-
(2002)
Circulation
, vol.105
, pp. 244-250
-
-
Michelakis, E.D.1
McMurtry, M.S.2
Wu, X.-C.3
Dyck, J.R.B.4
Moudgil, R.5
Hopkins, T.A.6
Lopaschuk, G.D.7
Puttagunta, L.8
Waite, R.9
Archer, S.L.10
-
291
-
-
84928404144
-
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension
-
[CrossRef] [PubMed]
-
Diebold, I.; Hennigs, J.K.; Miyagawa, K.; Li, C.G.; Nickel, N.P.; Kaschwich, M.; Cao, A.; Wang, L.; Reddy, S.; Chen, P.-I. et al. BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension. Cell Metab. 2015, 21, 596–608.[CrossRef] [PubMed]
-
(2015)
Cell Metab
, vol.21
, pp. 596-608
-
-
Diebold, I.1
Hennigs, J.K.2
Miyagawa, K.3
Li, C.G.4
Nickel, N.P.5
Kaschwich, M.6
Cao, A.7
Wang, L.8
Reddy, S.9
Chen, P.-I.10
-
292
-
-
84887080883
-
Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension
-
[CrossRef] [PubMed]
-
Fessel, J.P.; Flynn, C.R.; Robinson, L.J.; Penner, N.L.; Gladson, S.; Kang, C.J.; Wasserman, D.H.; Hemnes, A.R.; West, J.D. Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension. Am. J. Respir. Cell Mol. Biol. 2013, 49, 778–787.[CrossRef] [PubMed]
-
(2013)
Am. J. Respir. Cell Mol. Biol
, vol.49
, pp. 778-787
-
-
Fessel, J.P.1
Flynn, C.R.2
Robinson, L.J.3
Penner, N.L.4
Gladson, S.5
Kang, C.J.6
Wasserman, D.H.7
Hemnes, A.R.8
West, J.D.9
-
293
-
-
84873647966
-
Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy due to pulmonary arterial hypertension
-
[CrossRef] [PubMed]
-
Gomez-Arroyo, J.; Mizuno, S.; Szczepanek, K.; van Tassell, B.; Natarajan, R.; dos Remedios, C.G.; Drake, J.I.; Farkas, L.; Kraskauskas, D.; Wijesinghe, D.S. et al. Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy due to pulmonary arterial hypertension. Circ. Heart Fail. 2013, 6, 136–144.[CrossRef] [PubMed]
-
(2013)
Circ. Heart Fail
, vol.6
, pp. 136-144
-
-
Gomez-Arroyo, J.1
Mizuno, S.2
Szczepanek, K.3
Van Tassell, B.4
Natarajan, R.5
Dos Remedios, C.G.6
Drake, J.I.7
Farkas, L.8
Kraskauskas, D.9
Wijesinghe, D.S.10
-
294
-
-
84888636768
-
A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Sutendra, G.; Dromparis, P.; Paulin, R.; Zervopoulos, S.; Haromy, A.; Nagendran, J.; Michelakis, E.D. A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension. J. Mol. Med. 2013, 91, 1315–1327.[CrossRef] [PubMed]
-
(2013)
J. Mol. Med
, vol.91
, pp. 1315-1327
-
-
Sutendra, G.1
Dromparis, P.2
Paulin, R.3
Zervopoulos, S.4
Haromy, A.5
Nagendran, J.6
Michelakis, E.D.7
-
295
-
-
84890601822
-
Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension
-
[CrossRef] [PubMed]
-
Archer, S.L.; Fang, Y.-H.; Ryan, J.J.; Piao, L. Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension. Pulm. Circ. 2013, 3, 144–152.[CrossRef] [PubMed]
-
(2013)
Pulm. Circ
, vol.3
, pp. 144-152
-
-
Archer, S.L.1
Fang, Y.-H.2
Ryan, J.J.3
Piao, L.4
-
296
-
-
84864304711
-
Mitochondrial DNA damage and its consequences for mitochondrial gene expression
-
[CrossRef] [PubMed]
-
Cline, S.D. Mitochondrial DNA damage and its consequences for mitochondrial gene expression. Biochim. Biophys. Acta 2012, 1819, 979–991.[CrossRef] [PubMed]
-
(2012)
Biochim. Biophys. Acta
, vol.1819
, pp. 979-991
-
-
Cline, S.D.1
-
297
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
[PubMed]
-
Barja, G.; Herrero, A. Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J. 2000, 14, 312–318.[PubMed]
-
(2000)
FASEB J
, vol.14
, pp. 312-318
-
-
Barja, G.1
Herrero, A.2
-
298
-
-
0031032817
-
Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
-
[CrossRef] [PubMed]
-
Yakes, F.M.; Van Houten, B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA 1997, 94, 514–519.[CrossRef] [PubMed]
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 514-519
-
-
Yakes, F.M.1
Van Houten, B.2
-
299
-
-
84954494418
-
Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions
-
[CrossRef] [PubMed]
-
Tadi, S.K.; Sebastian, R.; Dahal, S.; Babu, R.K.; Choudhary, B.; Raghavan, S.C. Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions. Mol. Biol. Cell 2016, 27, 223–235.[CrossRef] [PubMed]
-
(2016)
Mol. Biol. Cell
, vol.27
, pp. 223-235
-
-
Tadi, S.K.1
Sebastian, R.2
Dahal, S.3
Babu, R.K.4
Choudhary, B.5
Raghavan, S.C.6
-
300
-
-
0034983837
-
Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes
-
Grishko, V.; Solomon, M.; Wilson, G.L.; LeDoux, S.P.; Gillespie, M.N. Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes. Am. J. Physiol. 2001, 280, L1300–L1308.
-
(2001)
Am. J. Physiol
, vol.280
, pp. L1300-L1308
-
-
Grishko, V.1
Solomon, M.2
Wilson, G.L.3
Ledoux, S.P.4
Gillespie, M.N.5
-
301
-
-
84928164761
-
Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with systemic lupus erythematosus
-
[CrossRef] [PubMed]
-
López-López, L.; Nieves-Plaza, M.; del Castro, M.R.; Font, Y.M.; Torres-Ramos, C.A.; Vilá, L.M.; Ayala-Peña, S. Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with systemic lupus erythematosus. Lupus 2014, 23, 1133–1141.[CrossRef] [PubMed]
-
(2014)
Lupus
, vol.23
, pp. 1133-1141
-
-
López-López, L.1
Nieves-Plaza, M.2
Del Castro, M.R.3
Font, Y.M.4
Torres-Ramos, C.A.5
Vilá, L.M.6
Ayala-Peña, S.7
-
302
-
-
84889251375
-
Pulmonary hypertension in systemic lupus erythematosus: Pulmonary thromboembolism is the leading cause
-
[CrossRef] [PubMed]
-
Akdogan, A.; Kilic, L.; Dogan, I.; Okutucu, S.; Er, E.; Kaya, B.; Coplu, L.; Calguneri, M.; Tokgozoglu, L.; Ertenli, I. Pulmonary hypertension in systemic lupus erythematosus: Pulmonary thromboembolism is the leading cause. J. Clin. Rheumatol. Pract. Rep. Rheum. Musculoskelet. Dis. 2013, 19, 421–425.[CrossRef] [PubMed]
-
(2013)
J. Clin. Rheumatol. Pract. Rep. Rheum. Musculoskelet. Dis
, vol.19
, pp. 421-425
-
-
Akdogan, A.1
Kilic, L.2
Dogan, I.3
Okutucu, S.4
Er, E.5
Kaya, B.6
Coplu, L.7
Calguneri, M.8
Tokgozoglu, L.9
Ertenli, I.10
-
303
-
-
0025217865
-
Pulmonary hypertension in systemic lupus erythematosus
-
[CrossRef] [PubMed]
-
Asherson, R.A. Pulmonary hypertension in systemic lupus erythematosus. J. Rheumatol. 1990, 17, 414–415.[CrossRef] [PubMed]
-
(1990)
J. Rheumatol
, vol.17
, pp. 414-415
-
-
Asherson, R.A.1
-
304
-
-
84977505897
-
Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease
-
[CrossRef] [PubMed]
-
Fetterman, J.L.; Holbrook, M.; Westbrook, D.G.; Brown, J.A.; Feeley, K.P.; Bretón-Romero, R.; Linder, E.A.; Berk, B.D.; Weisbrod, R.M.; Widlansky, M.E.; et al. Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease. Cardiovasc. Diabetol. 2016, 15, 53.[CrossRef] [PubMed]
-
(2016)
Cardiovasc. Diabetol
, vol.15
, pp. 53
-
-
Fetterman, J.L.1
Holbrook, M.2
Westbrook, D.G.3
Brown, J.A.4
Feeley, K.P.5
Bretón-Romero, R.6
Linder, E.A.7
Berk, B.D.8
Weisbrod, R.M.9
Widlansky, M.E.10
-
305
-
-
84881076472
-
Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress
-
[CrossRef] [PubMed]
-
Cheng, Y.; Ren, X.; Gowda, A.S.P.; Shan, Y.; Zhang, L.; Yuan, Y.-S.; Patel, R.; Wu, H.; Huber-Keener, K.; Yang, J.W. et al. Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress. Cell Death Dis. 2013, 4, e731.[CrossRef] [PubMed]
-
(2013)
Cell Death Dis
, pp. 4
-
-
Cheng, Y.1
Ren, X.2
Gowda, A.S.P.3
Shan, Y.4
Zhang, L.5
Yuan, Y.-S.6
Patel, R.7
Wu, H.8
Huber-Keener, K.9
Yang, J.W.10
-
306
-
-
84910135589
-
Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans
-
[CrossRef] [PubMed]
-
Paulin, R.; Dromparis, P.; Sutendra, G.; Gurtu, V.; Zervopoulos, S.; Bowers, L.; Haromy, A.; Webster, L.; Provencher, S.; Bonnet, S. et al. Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans. Cell Metab. 2014, 20, 827–839.[CrossRef] [PubMed]
-
(2014)
Cell Metab
, vol.20
, pp. 827-839
-
-
Paulin, R.1
Dromparis, P.2
Sutendra, G.3
Gurtu, V.4
Zervopoulos, S.5
Bowers, L.6
Haromy, A.7
Webster, L.8
Provencher, S.9
Bonnet, S.10
-
307
-
-
84941028477
-
Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: Implications for the regulation of mitochondrial function
-
[CrossRef] [PubMed]
-
Szczesny, B.; Brunyanszki, A.; Olah, G.; Mitra, S.; Szabo, C. Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: Implications for the regulation of mitochondrial function. Nucleic Acids Res. 2014, 42, 13161–13173.[CrossRef] [PubMed]
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 13161-13173
-
-
Szczesny, B.1
Brunyanszki, A.2
Olah, G.3
Mitra, S.4
Szabo, C.5
-
308
-
-
84900344357
-
+SIRT1 Reduction
-
[CrossRef] [PubMed]
-
+SIRT1 Reduction. Cell 2014, 157, 882–896.[CrossRef] [PubMed]
-
(2014)
Cell
, vol.157
, pp. 882-896
-
-
Fang, E.F.1
Scheibye-Knudsen, M.2
Brace, L.E.3
Kassahun, H.4
Sengupta, T.5
Nilsen, H.6
Mitchell, J.R.7
Croteau, D.L.8
Bohr, V.A.9
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