P53 gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 300, Issue 5, 2011, Pages

  Mizuno, Shiro ^a,b   Bogaard, Herman J ^b   Kraskauskas, Donatas ^b   Alhussaini, Aysar ^b   Gomez Arroyo, Jose ^b   Voelkel, Norbert F ^b   Ishizaki, Takeshi ^c  

^a Fukui Medical University   (Japan)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c UNIVERSITY OF FUKUI   (Japan)

Author keywords

Hypoxia inducible factor 1 ; P21; Platelet derived growth factor; Vascular endothelial growth factor

Indexed keywords

CYCLINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLATELET DERIVED GROWTH FACTOR; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE SILENCING; GENOTYPE; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE PRESSURE; HEART WEIGHT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; SYSTOLIC BLOOD PRESSURE; THICKNESS; WILD TYPE;

ANIMALS; ANOXIA; GENES, P53; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, KNOCKOUT; MICRORNAS; P21-ACTIVATED KINASES;

EID: 79955772507     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00286.2010     Document Type: Article

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