메뉴 건너뛰기




Volumn 43, Issue 6, 2015, Pages 3154-3166

Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; HISTONE H2AX; KAP1 PROTEIN; MRE11 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; RAD51 PROTEIN; UNCLASSIFIED DRUG; 2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE; 6-(4-HYDROXYPHENYL)-2-THIOXO-2,3-DIHYDRO-4(1H)-PYRIMIDINONE; ATM PROTEIN, HUMAN; DNA BINDING PROTEIN; HETEROCHROMATIN; MORPHOLINE DERIVATIVE; MRE11A PROTEIN, HUMAN; PYRIMIDINONE DERIVATIVE; PYRONE DERIVATIVE; RAD51 PROTEIN, HUMAN; THIOKETONE;

EID: 84942234504     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv160     Document Type: Article
Times cited : (105)

References (41)
  • 1
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh,Y. (2003) ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer, 3, 155-168.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 2
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist,C.J. and Kastan,M.B. (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature, 421, 499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 4
    • 0030750923 scopus 로고    scopus 로고
    • Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
    • Foray,N., Priestley,A., Alsbeih,G., Badie,C., Capulas,E.P., Arlett,C.F. and Malaise,E.P. (1997) Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks. Int. J. Radiat. Biol., 72, 271-283.
    • (1997) Int. J. Radiat. Biol. , vol.72 , pp. 271-283
    • Foray, N.1    Priestley, A.2    Alsbeih, G.3    Badie, C.4    Capulas, E.P.5    Arlett, C.F.6    Malaise, E.P.7
  • 5
    • 34249945536 scopus 로고    scopus 로고
    • DNA double-strand break repair: From mechanistic understanding to cancer treatment
    • Helleday,T., Lo,J., van Gent,D.C. and Engelward,B.P. (2007) DNA double-strand break repair: from mechanistic understanding to cancer treatment. DNA Repair (Amst), 6, 923-935.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 923-935
    • Helleday, T.1    Lo, J.2    Van Gent, D.C.3    Engelward, B.P.4
  • 6
    • 84866925311 scopus 로고    scopus 로고
    • Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
    • Kocher,S., Rieckmann,T., Rohaly,G., Mansour,W.Y., Dikomey,E., Dornreiter,I. and Dahm-Daphi,J. (2012) Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase. Nucleic Acids Res., 40, 8336-8347.
    • (2012) Nucleic Acids Res , vol.40 , pp. 8336-8347
    • Kocher, S.1    Rieckmann, T.2    Rohaly, G.3    Mansour, W.Y.4    Dikomey, E.5    Dornreiter, I.6    Dahm-Daphi, J.7
  • 7
    • 84877619314 scopus 로고    scopus 로고
    • DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair
    • Serrano,M.A., Li,Z., Dangeti,M., Musich,P.R., Patrick,S., Roginskaya,M., Cartwright,B. and Zou,Y. (2013) DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair. Oncogene, 32, 2452-2462.
    • (2013) Oncogene , vol.32 , pp. 2452-2462
    • Serrano, M.A.1    Li, Z.2    Dangeti, M.3    Musich, P.R.4    Patrick, S.5    Roginskaya, M.6    Cartwright, B.7    Zou, Y.8
  • 8
    • 3242891383 scopus 로고    scopus 로고
    • PARP-1, PARP-2 and ATM in the DNA damage response: Functional synergy in mouse development
    • Huber,A., Bai,P., de Murcia,J.M. and de Murcia,G. (2004) PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development. DNA Repair, 3, 1103-1108.
    • (2004) DNA Repair , vol.3 , pp. 1103-1108
    • Huber, A.1    Bai, P.2    De Murcia, J.M.3    De Murcia, G.4
  • 9
    • 0035131124 scopus 로고    scopus 로고
    • Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development
    • Menisser-de Murcia,J., Mark,M., Wendling,O., Wynshaw-Boris,A. and de Murcia,G. (2001) Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development. Mol. Cell. Biol., 21, 1828-1832.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1828-1832
    • Menisser-de Murcia, J.1    Mark, M.2    Wendling, O.3    Wynshaw-Boris, A.4    De Murcia, G.5
  • 10
    • 58149142799 scopus 로고    scopus 로고
    • Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair
    • Kirshner,M., Rathavs,M., Nizan,A., Essers,J., Kanaar,R., Shiloh,Y. and Barzilai,A. (2009) Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair. DNA Repair, 8, 253-261.
    • (2009) DNA Repair , vol.8 , pp. 253-261
    • Kirshner, M.1    Rathavs, M.2    Nizan, A.3    Essers, J.4    Kanaar, R.5    Shiloh, Y.6    Barzilai, A.7
  • 11
    • 84887014745 scopus 로고    scopus 로고
    • ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks
    • Kocher,S., Spies-Naumann,A., Kriegs,M., Dahm-Daphi,J. and Dornreiter,I. (2013) ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks. Radiother. Oncol., 108, 409-414.
    • (2013) Radiother. Oncol. , vol.108 , pp. 409-414
    • Kocher, S.1    Spies-Naumann, A.2    Kriegs, M.3    Dahm-Daphi, J.4    Dornreiter, I.5
  • 12
    • 77955601230 scopus 로고    scopus 로고
    • SnapShot: Homologous recombination in DNA double-strand break repair
    • Mazon,G., Mimitou,E.P. and Symington,L.S. (2010) SnapShot: homologous recombination in DNA double-strand break repair. Cell, 142, 646.e1.
    • (2010) Cell , vol.142 , pp. 646.e1
    • Mazon, G.1    Mimitou, E.P.2    Symington, L.S.3
  • 14
    • 35648986560 scopus 로고    scopus 로고
    • Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination
    • Takeda,S., Nakamura,K., Taniguchi,Y. and Paull,T.T. (2007) Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination. Mol. Cell, 28, 351-352.
    • (2007) Mol. Cell , vol.28 , pp. 351-352
    • Takeda, S.1    Nakamura, K.2    Taniguchi, Y.3    Paull, T.T.4
  • 15
    • 66149114020 scopus 로고    scopus 로고
    • Human CtIP mediates cell cycle control of DNA end resection and double strand break repair
    • Huertas,P. and Jackson,S.P. (2009) Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. J. Biol. Chem., 284, 9558-9565.
    • (2009) J. Biol. Chem. , vol.284 , pp. 9558-9565
    • Huertas, P.1    Jackson, S.P.2
  • 16
    • 0027978039 scopus 로고
    • Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein
    • Sung,P. (1994) Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein. Science, 265, 1241-1243.
    • (1994) Science , vol.265 , pp. 1241-1243
    • Sung, P.1
  • 17
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Paques,F. and Haber,J.E. (1999) Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev., 63, 349-404.
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 18
    • 0036336673 scopus 로고    scopus 로고
    • DNA double-strand break repair by homologous recombination
    • van den Bosch,M., Lohman,P.H. and Pastink,A. (2002) DNA double-strand break repair by homologous recombination. Biol. Chem., 383, 873-892.
    • (2002) Biol. Chem. , vol.383 , pp. 873-892
    • Van Den Bosch, M.1    Lohman, P.H.2    Pastink, A.3
  • 19
    • 84884630330 scopus 로고    scopus 로고
    • ATM release at resected double-strand breaks provides heterochromatin reconstitution to facilitate homologous recombination
    • Geuting,V., Reul,C. and Lobrich,M. (2013) ATM release at resected double-strand breaks provides heterochromatin reconstitution to facilitate homologous recombination. PLoS Genet., 9, e1003667.
    • (2013) PLoS Genet. , vol.9
    • Geuting, V.1    Reul, C.2    Lobrich, M.3
  • 22
    • 79551531093 scopus 로고    scopus 로고
    • Sister chromatid exchanges occur in G2-irradiated cells
    • Conrad,S., Kunzel,J. and Lobrich,M. (2011) Sister chromatid exchanges occur in G2-irradiated cells. Cell Cycle, 10, 222-228.
    • (2011) Cell Cycle , vol.10 , pp. 222-228
    • Conrad, S.1    Kunzel, J.2    Lobrich, M.3
  • 25
    • 84874654073 scopus 로고    scopus 로고
    • Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma
    • Mansour,W.Y., Bogdanova,N.V., Kasten-Pisula,U., Rieckmann,T., Kocher,S., Borgmann,K., Baumann,M., Krause,M., Petersen,C., Hu,H. et al. (2013) Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma. Radiother. Oncol., 106, 147-154.
    • (2013) Radiother. Oncol. , vol.106 , pp. 147-154
    • Mansour, W.Y.1    Bogdanova, N.V.2    Kasten-Pisula, U.3    Rieckmann, T.4    Kocher, S.5    Borgmann, K.6    Baumann, M.7    Krause, M.8    Petersen, C.9    Hu, H.10
  • 26
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: All's well that ends well
    • Wyman,C. and Kanaar,R. (2006) DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet., 40, 363-383.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 27
    • 84911953126 scopus 로고    scopus 로고
    • Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells
    • Kotter,A., Cornils,K., Borgmann,K., Dahm-Daphi,J., Petersen,C., Dikomey,E. and Mansour,W.Y. (2014) Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells. Mol. Oncol., 8, 1616-1625.
    • (2014) Mol. Oncol. , vol.8 , pp. 1616-1625
    • Kotter, A.1    Cornils, K.2    Borgmann, K.3    Dahm-Daphi, J.4    Petersen, C.5    Dikomey, E.6    Mansour, W.Y.7
  • 28
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • Goodarzi,A.A., Noon,A.T., Deckbar,D., Ziv,Y., Shiloh,Y., Lobrich,M. and Jeggo,P.A. (2008) ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell, 31, 167-177.
    • (2008) Mol. Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6    Jeggo, P.A.7
  • 30
    • 80052168685 scopus 로고    scopus 로고
    • The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
    • Helleday,T. (2011) The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings. Mol. Oncol., 5, 387-393.
    • (2011) Mol. Oncol. , vol.5 , pp. 387-393
    • Helleday, T.1
  • 31
    • 59949092789 scopus 로고    scopus 로고
    • A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair
    • Jain,S., Sugawara,N., Lydeard,J., Vaze,M., Tanguy Le Gac,N. and Haber,J.E. (2009) A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair. Genes Dev., 23, 291-303.
    • (2009) Genes Dev. , vol.23 , pp. 291-303
    • Jain, S.1    Sugawara, N.2    Lydeard, J.3    Vaze, M.4    Tanguy Le Gac, N.5    Haber, J.E.6
  • 36
    • 0037900075 scopus 로고    scopus 로고
    • A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament
    • Mazin,A.V., Alexeev,A.A. and Kowalczykowski,S.C. (2003) A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament. J. Biol. Chem., 278, 14029-14036.
    • (2003) J. Biol. Chem. , vol.278 , pp. 14029-14036
    • Mazin, A.V.1    Alexeev, A.A.2    Kowalczykowski, S.C.3
  • 37
    • 0036864703 scopus 로고    scopus 로고
    • Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments
    • Solinger,J.A., Kiianitsa,K. and Heyer,W.D. (2002) Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments. Mol. Cell, 10, 1175-1188.
    • (2002) Mol. Cell , vol.10 , pp. 1175-1188
    • Solinger, J.A.1    Kiianitsa, K.2    Heyer, W.D.3
  • 38
    • 33745484708 scopus 로고    scopus 로고
    • Terminal association of Rad54 protein with the Rad51-dsDNA filament
    • Kiianitsa,K., Solinger,J.A. and Heyer,W.D. (2006) Terminal association of Rad54 protein with the Rad51-dsDNA filament. Proc. Natl. Acad. Sci. U.S.A., 103, 9767-9772.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 9767-9772
    • Kiianitsa, K.1    Solinger, J.A.2    Heyer, W.D.3
  • 39
    • 0034141562 scopus 로고    scopus 로고
    • The controlling role of ATM in homologous recombinational repair of DNA damage
    • Morrison,C., Sonoda,E., Takao,N., Shinohara,A., Yamamoto,K. and Takeda,S. (2000) The controlling role of ATM in homologous recombinational repair of DNA damage. EMBO J., 19, 463-471.
    • (2000) EMBO J. , vol.19 , pp. 463-471
    • Morrison, C.1    Sonoda, E.2    Takao, N.3    Shinohara, A.4    Yamamoto, K.5    Takeda, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.