Cyclophosphamide enhances TNF-α-induced apoptotic cell death in murine vascular endothelial cell

FEBS Letters

Volumn 580, Issue 6, 2006, Pages 1597-1600

  Ohtani, Toshio ^a   Nakamura, Tomoyuki ^a   Toda, Ken Ichi ^b   Furukawa, Fukumi ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b Kitano Hospital   (Japan)

Author keywords

Bax; Caspase; Cyclophosphamide; Endothelial cell; TNF

Indexed keywords

4 HYDROXYCYCLOPHOSPHAMIDE; CASPASE 3 INHIBITOR; CASPASE 8; CASPASE 9; CYCLOPHOSPHAMIDE; DNA FRAGMENT; PROTEIN BAX; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; FRAGMENTATION REACTION; INFLAMMATION; METABOLITE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIRHEUMATIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELLS, CULTURED; CYCLOPHOSPHAMIDE; CYSTEINE ENDOPEPTIDASES; DNA FRAGMENTATION; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; MICE; POLY(ADP-RIBOSE) POLYMERASES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

ANIMALIA; MURINAE;

EID: 33344473537     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.01.092     Document Type: Article

References (18)

1. K.C. Zimmermann, and D.R. Green How cells die: apoptosis pathways J. Allergy Clin. Immunol. 108 2001 S99 S103
2. A. Eigler, B. Sinha, G. Hartmann, and S. Endres Taming TNF: strategies to restrain this proinflammatory cytokine Immunol. Today 18 1997 487 492
3. I. Uthman Pharmacological therapy of vasculitis: an update Curr. Opin. Pharmacol. 4 2004 177 182
4. L.P. Zhu, T.R. Cupps, G. Whalen, and A.S. Fauci Selective effects of cyclophosphamide therapy on activation, proliferation, and differentiation of human B cells J. Clin. Invest. 79 1987 1082 1090
5. K. Toda, K. Tsujioka, Y. Maruguchi, K. Ishii, Y. Miyachi, K. Kuribayashi, and S. Imamura Establishment and characterization of a tumorigenic vascular endothelial cell line (F-2) Cancer Res. 50 1990 5526 5530
6. S. Ren, T.F. Kalhorn, G.B. McDonald, C. Anasetti, F.R. Appelbaum, and J.T. Slattery Pharmacokinetics of cyclophosphamide and its metabolites in bone marrow transplantation patients Clin Pharmacol. Ther. 64 1998 289 301
7. Y. Hamano, H. Sugimoto, M.A. Soubasakos, M. Kieran, B.R. Olsen, J. Lawler, A. Sudhakar, and R. Kalluri Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression Cancer Res. 64 2004 1570 1574
8. M.R. Slowik, W. Min, T. Ardito, A. Karsan, M. Kashgarian, and J.S. Pober Evidence that tumor necrosis factor triggers apoptosis in human endothelial cells by interleukin-1-comverting enzyme-like protease-dependent and -independent pathways Lab. Invest. 77 1997 257 267
9. A. Karsan, E. Yee, and J.M. Harlan Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1 J. Biol. Chem. 271 1996 27201 27204
10. D. Wissing, H. Mouritzen, and M. Jaattela TNF-induced mitochondrial changes and activation of apoptotic proteases are inhibited by A20 Free Radic. Biol. Med. 25 1998 57 65
11. E.J. Ackerman, J.K. Taylor, R. Narayana, and C.F. Bennett The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides J. Biol. Chem. 274 1999 11245 11252
12. U.K. Meßmer, G. Winkel, V.A. Briner, and J. Pfeilschifter Glucocorticoids potently block tumor necrosis factor-α and lipopolysaccharide-induced apoptotic cell death in bovine glomerular endothelial cells upstream of caspase 3 activation Br. J. Pharmacol. 127 1999 1633 1640
13. A.S. Fauci, D.C. Dale, and J.E. Balow Glucocorticosteroid therapy mechanism of action and clinical considerations Ann. Intern. Med. 84 1976 304 315
14. S.H. Kaufmann, S. Desnoyers, Y. Ottaviano, N.E. Davidson, and G.G. Poirier Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis Cancer Res. 53 1993 3976 3985
15. H.R. Stennicke, J.M. Jurgensmeier, H. Shin, Q. Deveraux, B.B. Wolf, X. Yang, Q. Zhou, H.M. Ellerby, D. Bredesen, D.R. Green, J.C. Reed, C.J. Froelich, and G.S. Salvesen Pro-caspase-3 is a major physiologic target of caspase-8 J. Biol. Chem. 273 1998 27084 27090
16. A. Gross, X.M. Yin, K. Wang, M.C. Wei, J. Jockel, C. Milliman, H. Erdjument-Bromage, P. Tempst, and S.J. Korsmeyer Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-xL prevents this release but not tumor necrosis factor-R1/Fas death J. Biol. Chem. 274 1999 1156 1163
17. P.S. Schwartz, and D.J. Waxman Cyclophosphamide induces caspase-9 dependent apoptosis in 9L tumor cells Mol. Pharmacol. 60 2001 1268 1279
18. V.P. Skulachev Cytochrome c in the apoptotic and antioxidant cascades FEBS Lett. 423 1998 275 280