Oxidative stress mediates tumor necrosis factor-α-induced mitochondrial DNA damage and dysfunction in cardiac myocytes

Circulation

Volumn 107, Issue 10, 2003, Pages 1418-1423

  Suematsu, Nobuhiro ^a   Tsutsui, Hiroyuki ^a   Wen, Jing ^a   Kang, Dongchon ^a   Ikeuchi, Masaki ^a   Ide, Tomomi ^a   Hayashidani, Shunji ^a   Shiomi, Tetsuya ^a   Kubota, Toru ^a   Hamasaki, Naotaka ^a   Takeshita, Akira ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Antioxidants; Free radicals; Genes; Heart failure; Myocytes

Indexed keywords

ALPHA TOCOPHEROL; ANGIOTENSIN; ANTIOXIDANT; CERAMIDE; HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE INHIBITOR; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; HEART FAILURE; HEART VENTRICLE REMODELING; MUSCLE CELL; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SOUTHERN BLOTTING;

ANGIOTENSIN II; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CERAMIDES; DNA DAMAGE; DNA, MITOCHONDRIAL; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPHINGOMYELINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037453028     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000055318.09997.1F     Document Type: Article

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