ATP-generating glycolytic substrates prevent N-nitrosofenfluramine-induced cytotoxicity in isolated rat hepatocytes

Chemico-Biological Interactions

Volumn 164, Issue 1-2, 2006, Pages 93-101

  Nakagawa, Yoshio ^a   Tayama, Sumiko ^a   Ogata, Akio ^a   Suzuki, Toshinari ^a   Ishii, Hidemi ^b  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adenosine triphosphate; Appetite suppressant; Comet assay; Fructose; Hepatotoxicity; N Nitrosofenfluramine; Rat hepatocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; FENFLURAMINE; FRUCTOSE; GLUCOSE; GLUTATHIONE; MALONALDEHYDE; N NITROSOFENFLURAMINE; NITROSO DERIVATIVE; SUCROSE; UNCLASSIFIED DRUG; XYLITOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL PROTECTION; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; INCUBATION TIME; LIPID PEROXIDATION; LIVER CELL; MALE; MITOCHONDRIAL MEMBRANE; NONHUMAN; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL DEATH; CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FENFLURAMINE; GLUTATHIONE; GLYCOLYSIS; HEPATOCYTES; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; RATS; RATS, INBRED F344; TIME FACTORS;

EID: 33750715112     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2006.08.024     Document Type: Article

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