Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 10, 2001, Pages 1805-1814

  Cheng, Tzu Hurng ^d   Shih, Neng Lang ^b,d   Chen, Shin Yee ^d,e   Loh, Shih Hurng ^c   Cheng, Pao Yun ^c   Tsai, Chien Sung ^c   Liu, Shing Hwa ^b   Wang, Danny Ling ^d   Chen, Jin Jer ^a,b,d  

^a ACADEMIA SINICA   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^e QUEEN S UNIVERSITY   (Canada)

Author keywords

Activator protein 1; Cyclic strain; Endothelin 1; Ras Raf ERK signaling pathway; Reactive oxygen species

Indexed keywords

CATALASE; CHLORAMPHENICOL ACETYLTRANSFERASE; ENDOTHELIN 1; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE;

ARTICLE; BINDING SITE; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

BOVINAE;

EID: 0034771241     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1444     Document Type: Article

References (36)

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
2. Cyclical strain increases endothelin-1 secretion and gene expression in human endothelial cells
3. Mechanical strain increases endothelin-1 gene expression via protein kinase C pathway in human endothelial cells
4. Effects of mechanical forces on signal transduction and gene expression in endothelial cells
5. Mitogenic signaling mediated by oxidants in ras-transformed fibroblasts
6. Oxygen radicals as second messengers for expression of the monocyte chemo-attractant protein. JE/MCP-1. and the monocyte colony-stimulating factor, CSF-1. in response to tumor necrosis factor-α and immunoglobin G
7. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kB transcription factor and HIV-1
8. Nuclear factor-kB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress
9. Exposure of endothelial cells to cyclic strains induces c-fos, fosB and c-jun but not junB or junD and increases the transcriptional factor AP-1
10. Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion
11. 2 induces c-fos and c-jun gene expression and increases AP-1 activity
12. Cyclic strain-induced plasminogen activator inhibitor-1 (PAI-1) release from endothelial cells involves reactive oxygen species
13. Cyclic strain-induced monocyte chemotactic protein-1 gene expression involves reactive oxygen species activation of AP-1
14. Modulation of Ras/Raf/extracellular signal-regulated kinase pathway by reactive oxygen species is involved in cyclic strain-induced early growth response-1 gene expression in endothelial cells
15. Cooperative interaction of GATA-2 and AP-1 regulates transcription of the endothelin-l gene
16. Reactive oxygen species modulate endothelin-1-induced c-fos gene expression in eardiomyocytes
17. Endothelin-1 gene suppression by shear stress: Pharmacological evaluation of the role of tyrosine kinase, intracellular calcium, cytoskeleton, and mechanosensitive channels
18. Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells
19. Mechanical perturbation of cultured human endothelial cells causes rapid increases of intracellular calcium
20. Shear stress regulates endothelin-1 release via protein kinase C and cGMP in cultured endothelial cells
21. Protein kinase C is a mediator of the adaptation of vascular endothelial cells to cyclic strain in vitro
22. MAP kinase activation by flow in endothelial cells: Role of β1 integrins and tyrosine kinases
23. p21fas as a common signaling target of reactive free radicals and cellular redox stress
24. 2 and tumor necrosis factor-α activate intercellular adhesion molecule-1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter
25. 2-terminal kinase
26. Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter
27. Role of free radicals and catalytic metal ions in human disease: An overview
28. The effects of alpha-to-copherol supplementation on monocyte function
29. 2
30. Induction of c-fos expression through JNK-mediated TCF/Elk1 phosphorylation
31. Integration of MAP kinase signal transduction pathways at the serum response element
32. Role of P38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors
33. Mechanical strain induces monocyte chemotactic protein-1 gene expression in endothelial cells: Effects of mechanical strain on monocyte adhesion to endothelial cells
34. Fluid shear stress induces a biphasic response of human monocyte chemotactic protein-1 gene expression in vascular endothelium
35. Functional analysis of the endothelin-1 gene promotor: Evidence for an endothelial cell-specific cis-acting sequence
36. Regulation of endothelin-1 gene expression by Fos and Jun